[ { "uniprot_canonical_ac": "A0A9J7K956-1", "uniprot_ac": "A0A9J7K956", "uniprot_id": "A0A9J7K956_CRIGR", "mass": { "chemical_mass": 32763.0, "monoisotopic_mass": 32763.0 }, "refseq": { "ac": "XP_035300921", "name": "LIM and cysteine-rich domains protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300921" }, "gene_names": [ { "name": "Lmcd1", "type": "recommended", "evidence": [ { "id": "A0A9J7K956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K956" } ] }, { "name": "Lmcd1", "type": "synonym", "evidence": [ { "id": "XP_035300921", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300921" } ] } ], "protein_names": [ { "name": "LIM and cysteine-rich domains protein 1", "type": "recommended", "evidence": [ { "id": "A0A9J7K956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K956/entry#names_and_taxonomy" } ] }, { "name": "LIM and cysteine-rich domains protein 1", "type": "synonym", "evidence": [ { "id": "XP_035300921", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300921" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613678.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035300921", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300921" } ] }, { "annotation": "Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter. Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K956", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K956#function" }, { "database": "UniProtKB", "id": "ARBA00054580", "url": "https://www.uniprot.org/uniprotkb/ARBA00054580#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K956", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K956" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Lmcd1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K956", "locus": {} } ], "crossref": [ { "id": "A0A9J7K956", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7K956", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09340", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09340", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09829", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09829", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100773779", "url": "https://www.ncbi.nlm.nih.gov/gene/100773779", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010442", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010442", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033724", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033724", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047120", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047120", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773779", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773779", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7K956", "url": "https://www.orthodb.org/?gene=A0A9J7K956", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24211", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24211", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24211:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24211:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06297", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06297", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035300921", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300921", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7K956", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K956", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K956-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K956-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSKYATLTARVKGGDGIRIYKRNRMIMTNPIATGKDPTFDTITYEWAPPGVTQKLGLQYMELIPKEKQPVTGTEGALYRRRQLMHQLPIYDQDPSRCRGLVESELKAMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKTQEKLEGPETTAPTTNGSLGDPSKEVEYVCELCKGAAPADSPVVYADRAGYSKQWHPTCFVCIKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFSEDYQRVEDLAWHRKHFICEGCEQLLSGRAYIVTKGQLLCPTCSKSKRS", "length": 292, "header": "tr|A0A9J7K956-1|A0A9J7K956_CRIGR Isoform 1 of LIM and cysteine-rich domains protein 1 OS=Cricetulus griseus OX=10029 GN=Lmcd1 PE=4 SV=1 CANONICAL=A0A9J7K956-1" }, "isoforms": [ { "isoform_ac": "A0A9J7K956-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K956/entry#A0A9J7K956-1", "sequence": { "sequence": "MDSKYATLTARVKGGDGIRIYKRNRMIMTNPIATGKDPTFDTITYEWAPPGVTQKLGLQYMELIPKEKQPVTGTEGALYRRRQLMHQLPIYDQDPSRCRGLVESELKAMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKTQEKLEGPETTAPTTNGSLGDPSKEVEYVCELCKGAAPADSPVVYADRAGYSKQWHPTCFVCIKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFSEDYQRVEDLAWHRKHFICEGCEQLLSGRAYIVTKGQLLCPTCSKSKRS", "length": 292, "header": "tr|A0A9J7K956-1|A0A9J7K956_CRIGR Isoform 1 of LIM and cysteine-rich domains protein 1 OS=Cricetulus griseus OX=10029 GN=Lmcd1 PE=4 SV=1 CANONICAL=A0A9J7K956-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K956", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K956" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K956", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K956" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773779", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773779", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K956", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K956" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K956", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K956" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K956", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K956" } ], "pmid": "" }, { "name": "regulation of cardiac muscle hypertrophy", "id": "GO:0010611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010611", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K956", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K956" } ], "pmid": "" }, { "name": "positive regulation of calcineurin-NFAT signaling cascade", "id": "GO:0070886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K956", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K956" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K956", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K956" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K956", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K956" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7K956", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K956" }, { "id": "PS50023", "database": "PROSITE", "url": 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"sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7K964-1", "uniprot_ac": "A0A9J7K964", "uniprot_id": "A0A9J7K964_CRIGR", "mass": { "chemical_mass": 53082.0, "monoisotopic_mass": 53082.0 }, "refseq": { "ac": "XP_035300954", "name": "serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300954" }, "gene_names": [ { "name": "Ppp2r3c", "type": "recommended", "evidence": [ { "id": "A0A9J7K964", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K964" } ] }, { "name": "Ppp2r3c", "type": "synonym", "evidence": [ { "id": "XP_035300954", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300954" } ] } ], "protein_names": [ { "name": "Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma", "type": "recommended", "evidence": [ { "id": "A0A9J7K964", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K964/entry#names_and_taxonomy" } ] }, { "name": "serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035300954", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300954" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035300954", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300954" } ] }, { "annotation": "May regulate MCM3AP phosphorylation through phosphatase recruitment. May act as a negative regulator of ABCB1 expression and function through the dephosphorylation of ABCB1 by TFPI2/PPP2R3C complex. May play a role in the activation-induced cell death of B-cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K964", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K964#function" }, { "database": "UniProtKB", "id": "ARBA00057358", "url": "https://www.uniprot.org/uniprotkb/ARBA00057358#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K964", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K964" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ppp2r3c", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K964", "locus": {} } ], "crossref": [ { "id": "A0A9J7K964", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7K964", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd21505", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21505", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100752573", "url": "https://www.ncbi.nlm.nih.gov/gene/100752573", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041534", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041534", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR12085", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12085", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12085:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12085:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF17958", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17958", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035300954", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300954", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7K964", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K964", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K964-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K964-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYQPLKARFTSKKKNNHGKKSEQELKEEEMDLFTKYYSEWKGGRKNTNEFYKTIPRFYYRLPAEDEVLLQKLREESRAVFLQRKSRELLDNEELQNLWFLLDKHQIPPVIGEEAMINYENFLKVGEKAGPKCKQFFTAKVFAKLLHTDSYGRISIMQFFNYVMRKVWLHQTRIGLSLYDVAGQGYLRESDLENYILELIPTLPQLDGLEKSFYSFYVCTAVRKFFFFLDPLRTGKIKIQDILACSFLDDLLELRDEELSKESQETNWFSAPSALRVYGQYLNLDKDHNGMLSKEELSRYGTATMTNVFLDRVFQECLTYDGEMDYKTYLDFVLALENRKEPAALQYIFKLLDIENKGYLNVFSLNYFFRAIQELMKIHGQDPVSFQDVKDEIFDMVKPKDPLKISLQDLINSNQGDTVTTILIDLNGFWTYENREALVANDNENSADLDDT", "length": 451, "header": "tr|A0A9J7K964-1|A0A9J7K964_CRIGR Isoform 1 of Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma OS=Cricetulus griseus OX=10029 GN=Ppp2r3c PE=4 SV=1 CANONICAL=A0A9J7K964-1" }, "isoforms": [ { "isoform_ac": "A0A9J7K964-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K964/entry#A0A9J7K964-1", "sequence": { "sequence": "MYQPLKARFTSKKKNNHGKKSEQELKEEEMDLFTKYYSEWKGGRKNTNEFYKTIPRFYYRLPAEDEVLLQKLREESRAVFLQRKSRELLDNEELQNLWFLLDKHQIPPVIGEEAMINYENFLKVGEKAGPKCKQFFTAKVFAKLLHTDSYGRISIMQFFNYVMRKVWLHQTRIGLSLYDVAGQGYLRESDLENYILELIPTLPQLDGLEKSFYSFYVCTAVRKFFFFLDPLRTGKIKIQDILACSFLDDLLELRDEELSKESQETNWFSAPSALRVYGQYLNLDKDHNGMLSKEELSRYGTATMTNVFLDRVFQECLTYDGEMDYKTYLDFVLALENRKEPAALQYIFKLLDIENKGYLNVFSLNYFFRAIQELMKIHGQDPVSFQDVKDEIFDMVKPKDPLKISLQDLINSNQGDTVTTILIDLNGFWTYENREALVANDNENSADLDDT", "length": 451, "header": "tr|A0A9J7K964-1|A0A9J7K964_CRIGR Isoform 1 of Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma OS=Cricetulus griseus OX=10029 GN=Ppp2r3c PE=4 SV=1 CANONICAL=A0A9J7K964-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K964", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K964" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K964", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K964" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "regulation of dephosphorylation", "id": "GO:0035303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035303", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K964", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K964" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K964", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K964" } ], "pmid": "" }, { "name": "T cell homeostasis", "id": "GO:0043029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043029", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K964", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K964" } ], "pmid": "" }, { "name": "B cell homeostasis", "id": "GO:0001782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001782", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K964", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K964" } ], "pmid": "" }, { "name": "positive regulation of B cell differentiation", "id": "GO:0045579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045579", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K964", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K964" } ], "pmid": "" }, { "name": "cortical cytoskeleton organization", "id": "GO:0030865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030865", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K964", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K964" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K964", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K964" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K964", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K964" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K964", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K964" } ], "pmid": "" }, { "name": "spindle", "id": "GO:0005819", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005819", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K964", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K964" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K964", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K964" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7K964", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K964" }, { "id": "PF17958", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17958" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PP2A regulatory subunit B'' EF-hand", "eco_id": "ECO_0000259", "start_pos": 180, "end_pos": 256, "start_aa": "Val", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7K974-1", "uniprot_ac": "A0A9J7K974", "uniprot_id": "A0A9J7K974_CRIGR", "mass": { "chemical_mass": 56270.0, "monoisotopic_mass": 56270.0 }, "refseq": { "ac": "XP_035300989", "name": "polypyrimidine tract-binding protein 1 isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300989" }, "gene_names": [ { "name": "Ptbp1", "type": "recommended", "evidence": [ { "id": "A0A9J7K974", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K974" } ] }, { "name": "Ptbp1", "type": "synonym", "evidence": [ { "id": "XP_035300989", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300989" } ] } ], "protein_names": [ { "name": "Polypyrimidine tract-binding protein 1", "type": "recommended", "evidence": [ { "id": "A0A9J7K974", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K974/entry#names_and_taxonomy" } ] }, { "name": "Heterogeneous nuclear ribonucleoprotein I", "type": "synonym", "evidence": [ { "id": "A0A9J7K974", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K974/entry#names_and_taxonomy" } ] }, { "name": "polypyrimidine tract-binding protein 1 isoform X4", "type": "synonym", "evidence": [ { "id": "XP_035300989", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300989" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035300989", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300989" } ] }, { "annotation": "Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10. Binds to polypyrimidine-rich controlling element (PCE) of CFTR and promotes exon skipping of CFTR exon 9, thereby antagonizing TIA1 and its role in exon inclusion of CFTR exon 9. Plays a role in the splicing of pyruvate kinase PKM by binding repressively to a polypyrimidine tract flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K974", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K974#function" }, { "database": "UniProtKB", "id": "ARBA00055436", "url": "https://www.uniprot.org/uniprotkb/ARBA00055436#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K974", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K974" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ptbp1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K974", "locus": {} } ], "crossref": [ { "id": "A0A9J7K974", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7K974", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12695", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12695", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12777", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12777", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12782", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12782", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100752134", "url": "https://www.ncbi.nlm.nih.gov/gene/100752134", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021790", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021790", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055204", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055204", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15592", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15592", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11835", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11835", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13893", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13893", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22976", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22976", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035300989", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300989", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7K974", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K974", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K974-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K974-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSSTSAANGNDSKKFKGDNRSTGVPSRVIHVRKLPSDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAANTMVNYYTSVAPVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQSGNLALAASAAAVDAGMAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYTRPDLPSGDSQPSLDQTMAAAFGAPGIMSASPYAGAGFPPTFAIPQAAGLSVPNVHGALAPLAIPSAAAAAAAGRIAIPGLAGAGNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGSQAQLAMSHLNGHKLHGKSVRITLSKHQSVQLPREGQEDQGLTKDYGSSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEDDLKNLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIELHNHDLGENHHLRVSFSKSTI", "length": 525, "header": "tr|A0A9J7K974-1|A0A9J7K974_CRIGR Isoform 1 of Polypyrimidine tract-binding protein 1 OS=Cricetulus griseus OX=10029 GN=Ptbp1 PE=4 SV=1 CANONICAL=A0A9J7K974-1" }, "isoforms": [ { "isoform_ac": "A0A9J7K974-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K974/entry#A0A9J7K974-1", "sequence": { "sequence": "MSSSTSAANGNDSKKFKGDNRSTGVPSRVIHVRKLPSDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAANTMVNYYTSVAPVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQSGNLALAASAAAVDAGMAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYTRPDLPSGDSQPSLDQTMAAAFGAPGIMSASPYAGAGFPPTFAIPQAAGLSVPNVHGALAPLAIPSAAAAAAAGRIAIPGLAGAGNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGSQAQLAMSHLNGHKLHGKSVRITLSKHQSVQLPREGQEDQGLTKDYGSSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEDDLKNLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIELHNHDLGENHHLRVSFSKSTI", "length": 525, "header": "tr|A0A9J7K974-1|A0A9J7K974_CRIGR Isoform 1 of Polypyrimidine tract-binding protein 1 OS=Cricetulus griseus OX=10029 GN=Ptbp1 PE=4 SV=1 CANONICAL=A0A9J7K974-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K974", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K974" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K974", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K974" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K974", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K974" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K974", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K974" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K974", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K974" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K974", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K974" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K974", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K974" } ], "pmid": "" }, { "name": "negative regulation of mRNA metabolic process", "id": "GO:1903312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903312", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K974", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K974" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 11, "end_pos": 13, "annotation": "n_glycosylation_sequon" }, { "start_pos": 20, "end_pos": 22, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7K974", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K974" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 28, "end_pos": 112, "start_aa": "Arg", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 11, "end_pos": 13 }, { "start_pos": 20, "end_pos": 22 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7K982-1", "uniprot_ac": "A0A9J7K982", "uniprot_id": "A0A9J7K982_CRIGR", "mass": { "chemical_mass": 109017.0, "monoisotopic_mass": 109017.0 }, "refseq": { "ac": "XP_035302693", "name": "sodium-driven chloride bicarbonate exchanger isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302693" }, "gene_names": [ { "name": "Slc4a10", "type": "recommended", "evidence": [ { "id": "A0A9J7K982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K982" } ] }, { "name": "Slc4a10", "type": "synonym", "evidence": [ { "id": "XP_035302693", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302693" } ] } ], "protein_names": [ { "name": "Anion exchange protein", "type": "recommended", "evidence": [ { "id": "A0A9J7K982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K982/entry#names_and_taxonomy" } ] }, { "name": "sodium-driven chloride bicarbonate exchanger isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035302693", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302693" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035302693", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302693" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K982", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K982" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Slc4a10", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K982", "locus": {} } ], "crossref": [ { "id": "A0A9J7K982", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7K982", "database": "AlphaFoldDB", "categories": [] }, { "id": "100766143", "url": "https://www.ncbi.nlm.nih.gov/gene/100766143", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011531", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011531", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013769", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013769", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766143", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766143", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7K982", "url": "https://www.orthodb.org/?gene=A0A9J7K982", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11453:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11453:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00955", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00955", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07565", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07565", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035302693", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302693", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H0P1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0P1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H0P1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0P1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1I1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1I1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1I1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1I1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K982", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K982", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K982-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K982-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHLYRWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCVLNGTVLLDMHANTLEEIANMVLDQQVSSGQLNEDVRHRVHEALMKQHHHQNQKKLTNRIPIVRSFADIGKKQSEPNSMDKNAGQLVSPQSAPACAENKNDVSRENSTVDFSKVDLHFMKKIPPGAEASNILVGELEFLERTVVAFVRLSPAVLLQGLAEVPIPSRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPAVPNGTAAHGEAEQHGGHSGPELQRTGRIFGGLILDIKRKAPFFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSEAYPINMHNDLELLTQYSCNCVEPHSPSNDTLKEWRESNISASDIIWGNLSVSECRSLHGEYVGRACGHGHPYVPDVLFWSVILFFSTVTMSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPTRDDRGWFVTPLGPNPWWTIIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQLFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTVIQMSCLGLLWIIKVSRAAIVFPMMVLALVFVRKLMDFLFTKRELSWLDDLMPESKKKKLEDAEKEEEQSMLAMEEEGTVQLPLEGHYRDDPSVINISDEMSKTAMWGNLLVTADNSKDKESRFPSKSIESRKEKKADSGKGVDRETCL", "length": 972, "header": "tr|A0A9J7K982-1|A0A9J7K982_CRIGR Isoform 1 of Anion exchange protein OS=Cricetulus griseus OX=10029 GN=Slc4a10 PE=3 SV=1 CANONICAL=A0A9J7K982-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H0P1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K982/entry#A0A9J7H0P1-1", "sequence": { "sequence": "MHANTLEEIANMVLDQQVSSGQLNEDVRHRVHEALMKQHHHQNQKKLTNRIPIVRSFADIGKKQSEPNSMDKNGQLVSPQSAPACAENKNDVSRENSTVDFSKVDLHFMKKIPPGAEASNILVGELEFLERTVVAFVRLSPAVLLQGLAEVPIPSRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPAVPNGTAAHGEAEQHGGHSGPELQRTGRIFGGLILDIKRKAPFFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSEAYPINMHNDLELLTQYSCNCVEPHSPSNDTLKEWRESNISASDIIWGNLSVSECRSLHGEYVGRACGHGHPYVPDVLFWSVILFFSTVTMSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPTRDDRGWFVTPLGPNPWWTIIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQLFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTVIQMSCLGLLWIIKVSRAAIVFPMMVLALVFVRKLMDFLFTKRELSWLDDLMPESKKKKLEDAEKEEEQSMLAMEEEGTVQLPLEGHYRDDPSVINISDEMSKTAMWGNLLVTADNSKDKESRFPSKSIESRKEKKADSGKGVDRETCL", "length": 923, "header": "tr|A0A9J7H0P1-1|A0A9J7H0P1_CRIGR Computationally mapped isoform of Anion exchange protein OS=Cricetulus griseus OX=10029 GN=Slc4a10 PE=3 SV=1 CANONICAL=A0A9J7K982-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H1I1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K982/entry#A0A9J7H1I1-1", "sequence": { "sequence": "MHANTLEEIANMVLDQQVSSGQLNEDVRHRVHEALMKQHHHQNQKKLTNRIPIVRSFADIGKKQSEPNSMDKNAGQLVSPQSAPACAENKNDVSRENSTVDFSKVDLHFMKKIPPGAEASNILVGELEFLERTVVAFVRLSPAVLLQGLAEVPIPSRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPAVPNGTAAHGEAEQHGGHSGPELQRTGRIFGGLILDIKRKAPFFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSEAYPINMHNDLELLTQYSCNCVEPHSPSNDTLKEWRESNISASDIIWGNLSVSECRSLHGEYVGRACGHGHPYVPDVLFWSVILFFSTVTMSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPTRDDRGWFVTPLGPNPWWTIIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQLFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTVIQMSCLGLLWIIKVSRAAIVFPMMVLALVFVRKLMDFLFTKRELSWLDDLMPESKKKKLEDAEKEEEQSMLAMEEEGTVQLPLEGHYRDDPSVINISDEMSKTAMWGNLLVTADNSKDKESRFPSKSIESRKEKKADSGKGVDRETCL", "length": 924, "header": "tr|A0A9J7H1I1-1|A0A9J7H1I1_CRIGR Computationally mapped isoform of Anion exchange protein OS=Cricetulus griseus OX=10029 GN=Slc4a10 PE=3 SV=1 CANONICAL=A0A9J7K982-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K982-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K982/entry#A0A9J7K982-1", "sequence": { "sequence": "MHLYRWLKFEEDVEDGGERWSKPYVATLSLHSLFELRSCVLNGTVLLDMHANTLEEIANMVLDQQVSSGQLNEDVRHRVHEALMKQHHHQNQKKLTNRIPIVRSFADIGKKQSEPNSMDKNAGQLVSPQSAPACAENKNDVSRENSTVDFSKVDLHFMKKIPPGAEASNILVGELEFLERTVVAFVRLSPAVLLQGLAEVPIPSRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLDQVTVLPPGEWDPSIRIEPPKNVPSQEKRKIPAVPNGTAAHGEAEQHGGHSGPELQRTGRIFGGLILDIKRKAPFFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEATEGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRASIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSEAYPINMHNDLELLTQYSCNCVEPHSPSNDTLKEWRESNISASDIIWGNLSVSECRSLHGEYVGRACGHGHPYVPDVLFWSVILFFSTVTMSATLKQFKTSRYFPTKVRSIVSDFAVFLTILCMVLIDYAIGIPSPKLQVPSVFKPTRDDRGWFVTPLGPNPWWTIIAAIIPALLCTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFLYMGASSLKGIQLFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTVIQMSCLGLLWIIKVSRAAIVFPMMVLALVFVRKLMDFLFTKRELSWLDDLMPESKKKKLEDAEKEEEQSMLAMEEEGTVQLPLEGHYRDDPSVINISDEMSKTAMWGNLLVTADNSKDKESRFPSKSIESRKEKKADSGKGVDRETCL", "length": 972, "header": "tr|A0A9J7K982-1|A0A9J7K982_CRIGR Isoform 1 of Anion exchange protein OS=Cricetulus griseus OX=10029 GN=Slc4a10 PE=3 SV=1 CANONICAL=A0A9J7K982-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K982", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K982" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K982", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K982" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766143", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766143", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K982", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K982" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K982", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K982" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "monoatomic anion transmembrane transporter activity", "id": "GO:0008509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008509", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K982", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K982" } ], "pmid": "" }, { "name": "solute:inorganic anion antiporter activity", "id": "GO:0005452", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005452", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K982", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K982" } ], "pmid": "" }, { "name": "sodium:bicarbonate symporter activity", "id": "GO:0008510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008510", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K982", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K982" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of intracellular pH", "id": "GO:0051453", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051453", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K982", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K982" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 293, "end_pos": 295, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 513, "end_pos": 515, "annotation": "n_glycosylation_sequon" }, { "start_pos": 523, "end_pos": 525, "annotation": "n_glycosylation_sequon" }, { "start_pos": 533, "end_pos": 535, "annotation": "n_glycosylation_sequon" }, { "start_pos": 919, "end_pos": 921, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7K982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K982" }, { "id": "PF07565", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07565" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Band 3 cytoplasmic", "eco_id": "ECO_0000259", "start_pos": 5, "end_pos": 270, "start_aa": "Arg", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7K982", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K982" }, { "id": "PF00955", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00955" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Bicarbonate transporter-like transmembrane", "eco_id": "ECO_0000259", "start_pos": 317, "end_pos": 876, "start_aa": "Arg", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 145, "end_pos": 147 }, { "start_pos": 293, "end_pos": 295 }, { "start_pos": 42, "end_pos": 44 }, { "start_pos": 513, "end_pos": 515 }, { "start_pos": 523, "end_pos": 525 }, { "start_pos": 533, "end_pos": 535 }, { "start_pos": 919, "end_pos": 921 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7K983-1", "uniprot_ac": "A0A9J7K983", "uniprot_id": "A0A9J7K983_CRIGR", "mass": { "chemical_mass": 53016.0, "monoisotopic_mass": 53016.0 }, "refseq": { "ac": "XP_035304996", "name": "carcinoembryonic antigen-related cell adhesion molecule 6 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304996" }, "gene_names": [ { "name": "LOC100756319", "type": "recommended", "evidence": [ { "id": "A0A9J7K983", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K983" } ] }, { "name": "LOC100756319", "type": "synonym", "evidence": [ { "id": "XP_035304996", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304996" } ] } ], "protein_names": [ { "name": "Carcinoembryonic antigen-related cell adhesion molecule 6 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7K983", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K983/entry#names_and_taxonomy" } ] }, { "name": "carcinoembryonic antigen-related cell adhesion molecule 6 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035304996", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304996" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 5% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304996", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304996" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K983", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K983" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100756319", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K983", "locus": {} } ], "crossref": [ { "id": "A0A9J7K983", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7K983", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05774", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05774", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100756319", "url": "https://www.ncbi.nlm.nih.gov/gene/100756319", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050831", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050831", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756319", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756319", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7K983", "url": "https://www.orthodb.org/?gene=A0A9J7K983", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44427", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44427", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44427:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44427:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13895", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13895", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304996", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304996", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7K983", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K983", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K983-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K983-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPPSALLPTCVPWQGLLLTASLLAMCNVPTTAEATTESVPPAVLEGSSVLLLAHNLPGNLSAYHWFKGEKPLDKNLIVTYDITSQEMKRGKLHDGRETLYPNGSLMLQNVTLKQSGIYNLNIQSAESDQKSVLVEVFVYPRLSKPSIRSNGTTAVEGQEAVELTCDPPFLKTTYVWRLNGKELPGDNNVSLSQSNTTLTLLKVSRHFTGHYECEVQNPLSAFRSNPFTLDVYYGPDTPKIFPPYKYFEEGQSLWLSCQATSYPEAQYSWIINGKPRKSDQEVFIHKVSPSNSGLYTCLVNNPTTGRDNFKVKEVTVVEKLRKPHIQIKNKTVLEHHFVDLTCVSENPGISIWWTFNNKRLKTTDRVVFTLNNRSLTIGPITKEDAGAYQCEVSNPFNSRLSDPVSLAVLYEPSKRNYPISAPMAAALVVEFLAGLAILGGLAYFVFFKKLHTRAETEKAASAKKAGDKGDYKSIPT", "length": 477, "header": "tr|A0A9J7K983-1|A0A9J7K983_CRIGR Isoform 1 of Carcinoembryonic antigen-related cell adhesion molecule 6 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100756319 PE=3 SV=1 CANONICAL=A0A9J7K983-1" }, "isoforms": [ { "isoform_ac": "A0A9J7K983-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K983/entry#A0A9J7K983-1", "sequence": { "sequence": "MDPPSALLPTCVPWQGLLLTASLLAMCNVPTTAEATTESVPPAVLEGSSVLLLAHNLPGNLSAYHWFKGEKPLDKNLIVTYDITSQEMKRGKLHDGRETLYPNGSLMLQNVTLKQSGIYNLNIQSAESDQKSVLVEVFVYPRLSKPSIRSNGTTAVEGQEAVELTCDPPFLKTTYVWRLNGKELPGDNNVSLSQSNTTLTLLKVSRHFTGHYECEVQNPLSAFRSNPFTLDVYYGPDTPKIFPPYKYFEEGQSLWLSCQATSYPEAQYSWIINGKPRKSDQEVFIHKVSPSNSGLYTCLVNNPTTGRDNFKVKEVTVVEKLRKPHIQIKNKTVLEHHFVDLTCVSENPGISIWWTFNNKRLKTTDRVVFTLNNRSLTIGPITKEDAGAYQCEVSNPFNSRLSDPVSLAVLYEPSKRNYPISAPMAAALVVEFLAGLAILGGLAYFVFFKKLHTRAETEKAASAKKAGDKGDYKSIPT", "length": 477, "header": "tr|A0A9J7K983-1|A0A9J7K983_CRIGR Isoform 1 of Carcinoembryonic antigen-related cell adhesion molecule 6 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100756319 PE=3 SV=1 CANONICAL=A0A9J7K983-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K983", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K983" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"https://www.uniprot.org/uniprotkb/A0A9J7K983" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K983", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K983" } ], "pmid": "" }, { "name": "regulation of immune system process", "id": "GO:0002682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002682", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K983", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K983" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein tyrosine kinase binding", "id": "GO:1990782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990782", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K983", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K983" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { 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"https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 141, "end_pos": 231, "start_aa": "Pro", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 }, { "start_pos": 110, "end_pos": 112 }, { "start_pos": 151, "end_pos": 153 }, { "start_pos": 189, "end_pos": 191 }, { "start_pos": 196, "end_pos": 198 }, { "start_pos": 330, "end_pos": 332 }, { "start_pos": 373, "end_pos": 375 }, { "start_pos": 60, "end_pos": 62 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"uniprot_ac": "A0A9J7K995", "uniprot_id": "A0A9J7K995_CRIGR", "mass": { "chemical_mass": 96868.0, "monoisotopic_mass": 96868.0 }, "refseq": { "ac": "XP_035305029", "name": "zinc finger protein 54 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305029" }, "gene_names": [ { "name": "LOC100751297", "type": "recommended", "evidence": [ { "id": "A0A9J7K995", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K995" } ] }, { "name": "LOC100751297", "type": "synonym", "evidence": [ { "id": "XP_035305029", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305029" } ] } ], "protein_names": [ { "name": "Zinc finger protein 54 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7K995", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K995/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 54 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035305029", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305029" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 15% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305029", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305029" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K995", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K995" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100751297", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K995", "locus": {} } ], "crossref": [ { "id": "A0A9J7K995", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7K995", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100751297", "url": "https://www.ncbi.nlm.nih.gov/gene/100751297", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751297", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751297", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7K995", "url": "https://www.orthodb.org/?gene=A0A9J7K995", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14003:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14003:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305029", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305029", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7K995", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K995", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K995-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K995-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQPETEVVPWKGGIAWCRLGRLENSPQLPEPQGRPGKVSSQQRSGGNRSPAALEAPRSEELRGWDPGGRERASGGASGFSAAHQEAGSEILLWISFLKDPRGFNLKTLGDLSIRYGMVFLGLLGMSASEGLLTFSDVTVYFTKDEWECLDCAQRALYIDVILENYSNLLSVENYYKCDPVHQHVKTEKESCQCNEPGKVLHDPSTCARYRTSETTENSNNYTCSNHREASVDSSNPDRHESMHSGEEPCRSIDCEKSLNLCSNITKDQRVYTAKKEHRQGECDDCFTFVYSPLQQPIYTGEKQHQSEKCFSSASSKIHTGKKPYKCNICDKSFTQCSNLKAHQRIHTGEKPYKCEGPLITQTCSPVQQNRGAWKMERKETEPKDAGRQAVYSSRHLVFLKEKFKEEKQEMADSPEHVSQGVLTFFDVAVNFSREEWQCLDSAQRALCIDVMLENYSNLAYVENYYKCDPVHRHVKTEKESCQCNELGKVPHDPSTCALYRTSEIAENSDNYTCSNHRDASADSSNPDRHESMHTGEEPCISKDCEKSLNLCSDITQDQRVYTTKKVQRQRKYDDSLSSTYGFMQQTIYIGKKPHQCGKCGECFKTTSNLSRHQRIHTGARPYRCKVCDKSFYTSPMLKQHHRIHTGEKPYKCNVCEKSFNWCLSFVRHQRVHTGEKPYKCAVCDKSFNVSSNLKVHQKTHTGEKPYKCMECDKSFTRNAHLQRHQRVHTGEKPYRCTECGKSFCKYSSVREHQKIHTGEKTYKCEACGISFSQYSNLRKHQRVHPKERPYSCKECGKFYTSTTYLKVHQKIHTGEKRYKCKKCGKSFSQYANLREHYSVHTQETP", "length": 845, "header": "tr|A0A9J7K995-1|A0A9J7K995_CRIGR Isoform 1 of Zinc finger protein 54 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100751297 PE=3 SV=1 CANONICAL=A0A9J7K995-1" }, "isoforms": [ { "isoform_ac": "A0A9J7K995-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K995/entry#A0A9J7K995-1", "sequence": { "sequence": "MQPETEVVPWKGGIAWCRLGRLENSPQLPEPQGRPGKVSSQQRSGGNRSPAALEAPRSEELRGWDPGGRERASGGASGFSAAHQEAGSEILLWISFLKDPRGFNLKTLGDLSIRYGMVFLGLLGMSASEGLLTFSDVTVYFTKDEWECLDCAQRALYIDVILENYSNLLSVENYYKCDPVHQHVKTEKESCQCNEPGKVLHDPSTCARYRTSETTENSNNYTCSNHREASVDSSNPDRHESMHSGEEPCRSIDCEKSLNLCSNITKDQRVYTAKKEHRQGECDDCFTFVYSPLQQPIYTGEKQHQSEKCFSSASSKIHTGKKPYKCNICDKSFTQCSNLKAHQRIHTGEKPYKCEGPLITQTCSPVQQNRGAWKMERKETEPKDAGRQAVYSSRHLVFLKEKFKEEKQEMADSPEHVSQGVLTFFDVAVNFSREEWQCLDSAQRALCIDVMLENYSNLAYVENYYKCDPVHRHVKTEKESCQCNELGKVPHDPSTCALYRTSEIAENSDNYTCSNHRDASADSSNPDRHESMHTGEEPCISKDCEKSLNLCSDITQDQRVYTTKKVQRQRKYDDSLSSTYGFMQQTIYIGKKPHQCGKCGECFKTTSNLSRHQRIHTGARPYRCKVCDKSFYTSPMLKQHHRIHTGEKPYKCNVCEKSFNWCLSFVRHQRVHTGEKPYKCAVCDKSFNVSSNLKVHQKTHTGEKPYKCMECDKSFTRNAHLQRHQRVHTGEKPYRCTECGKSFCKYSSVREHQKIHTGEKTYKCEACGISFSQYSNLRKHQRVHPKERPYSCKECGKFYTSTTYLKVHQKIHTGEKRYKCKKCGKSFSQYANLREHYSVHTQETP", "length": 845, "header": "tr|A0A9J7K995-1|A0A9J7K995_CRIGR Isoform 1 of Zinc finger protein 54 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100751297 PE=3 SV=1 CANONICAL=A0A9J7K995-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035302929", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302929" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9F3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9F3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tgm3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9F3", "locus": {} } ], "crossref": [ { "id": "A0A9J7K9F3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7K9F3", "database": "AlphaFoldDB", "categories": [] }, { "id": "100752403", "url": "https://www.ncbi.nlm.nih.gov/gene/100752403", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001102", 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9F3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9F3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9F3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9F3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752403", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752403", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9F3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9F3" } ], "pmid": "" }, { "name": "protein-glutamine gamma-glutamyltransferase activity", "id": "GO:0003810", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003810", "evidence": [ { "database": 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Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616291.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: incomplete on the amino end.", "evidence": [ { "database": "RefSeq", "id": "XP_035293532", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293532" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9H4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9H4#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9H4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9H4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100763730", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9H4", "locus": {} } ], "crossref": [ { "id": "A0A9J7K9H4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7K9H4", "database": "AlphaFoldDB", "categories": [] }, { "id": "100763730", "url": "https://www.ncbi.nlm.nih.gov/gene/100763730", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050758", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050758", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763730", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763730", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7K9H4", "url": "https://www.orthodb.org/?gene=A0A9J7K9H4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035293532", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293532", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7K9H4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9H4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9H4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9H4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "PEAILKMKKVDFPHQRCLCRGKSQHDSSHQICVKPAFPNDVSKEITERGSYHSTTEDLWKDGDPTKRDQQNQIPLLSSGAFFNQKTLRSDNSYEWEATGRSIPLGLHLISTQKRLPKCCSIEKTLQPNSNLQANSEHQSSSTKQPNGIVESCQFFTQGPSNAVCTIPNREEKAFKGKDFERILNPKQPLLQHEILSEDQPVEYTKYTALCQQQITNTIETPFICHICGKSFLQKSQLSSHPGTNRGETASECPDCLKSLTSPSSLQVPQEVHTKEKPYKCHDCGKSFSYASHLKVHLRIHTGERPYVCSDCGKAFSQKSVLTTHQRIHTGEKPYTCSHCGKMFVYASDLKKHSRFHTGEKPYECPDCGKLFSNKSHLPVHHRIHTGERPYKCRDCGKSFRRKCHLKVHNRVHTGEKPYICSECGKAFSHSSVLSTHQRIHTGEKPYTCSDCGKAMSSKAQLSEHQRIHTGEKPFVCMECGRAFSGRSSLQAHRRTHSSEKPFVCPKCGKGFLRRSQLSSHQQTHTAESP", "length": 529, "header": "tr|A0A9J7K9H4-1|A0A9J7K9H4_CRIGR Isoform 1 of Zinc finger protein 660 OS=Cricetulus griseus OX=10029 GN=LOC100763730 PE=3 SV=1 CANONICAL=A0A9J7K9H4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7K9H4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9H4/entry#A0A9J7K9H4-1", "sequence": { "sequence": "PEAILKMKKVDFPHQRCLCRGKSQHDSSHQICVKPAFPNDVSKEITERGSYHSTTEDLWKDGDPTKRDQQNQIPLLSSGAFFNQKTLRSDNSYEWEATGRSIPLGLHLISTQKRLPKCCSIEKTLQPNSNLQANSEHQSSSTKQPNGIVESCQFFTQGPSNAVCTIPNREEKAFKGKDFERILNPKQPLLQHEILSEDQPVEYTKYTALCQQQITNTIETPFICHICGKSFLQKSQLSSHPGTNRGETASECPDCLKSLTSPSSLQVPQEVHTKEKPYKCHDCGKSFSYASHLKVHLRIHTGERPYVCSDCGKAFSQKSVLTTHQRIHTGEKPYTCSHCGKMFVYASDLKKHSRFHTGEKPYECPDCGKLFSNKSHLPVHHRIHTGERPYKCRDCGKSFRRKCHLKVHNRVHTGEKPYICSECGKAFSHSSVLSTHQRIHTGEKPYTCSDCGKAMSSKAQLSEHQRIHTGEKPFVCMECGRAFSGRSSLQAHRRTHSSEKPFVCPKCGKGFLRRSQLSSHQQTHTAESP", "length": 529, "header": "tr|A0A9J7K9H4-1|A0A9J7K9H4_CRIGR Isoform 1 of Zinc finger protein 660 OS=Cricetulus griseus OX=10029 GN=LOC100763730 PE=3 SV=1 CANONICAL=A0A9J7K9H4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9H4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9H4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9H4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9H4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763730", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763730", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9H4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9H4" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9H4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9H4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9H4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9H4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9H4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9H4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 373, "end_pos": 375, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7K9H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9H4" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 222, "end_pos": 249, "start_aa": "Phe", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 373, "end_pos": 375 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7K9I1-1", "uniprot_ac": "A0A9J7K9I1", "uniprot_id": "A0A9J7K9I1_CRIGR", "mass": { "chemical_mass": 145355.0, "monoisotopic_mass": 145355.0 }, "refseq": { "ac": "XP_035301334", "name": "contactin-associated protein-like 5 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301334" }, "gene_names": [ { "name": "Cntnap5", "type": "recommended", "evidence": [ { "id": "A0A9J7K9I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9I1" } ] }, { "name": "Cntnap5", "type": "synonym", "evidence": [ { "id": "XP_035301334", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301334" } ] } ], "protein_names": [ { "name": "Contactin-associated protein-like 5 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7K9I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9I1/entry#names_and_taxonomy" } ] }, { "name": "contactin-associated protein-like 5 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035301334", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301334" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035301334", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301334" } ] }, { "annotation": "May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercellular communication.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9I1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9I1#function" }, { "database": "UniProtKB", "id": "ARBA00003165", "url": "https://www.uniprot.org/uniprotkb/ARBA00003165#function" }, { "database": "UniProtKB", "id": "A0A8C2MYX6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYX6#function" }, { "database": "UniProtKB", "id": "A0A9J7GZ64", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZ64#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9I1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9I1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cntnap5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9I1", "locus": {} } ], "crossref": [ { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00057", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00057", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00110", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00110", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100766518", "url": "https://www.ncbi.nlm.nih.gov/gene/100766518", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000421", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000421", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001791", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001791", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766518", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766518", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7K9I1", "url": "https://www.orthodb.org/?gene=A0A9J7K9I1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15036", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15036", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15036:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15036:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00754", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00754", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02210", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02210", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035301334", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301334", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MYX6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MYX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYX6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZ64", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZ64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZ64-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZ64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9I1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9I1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9I1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9I1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSVPRLTSVLTLMLSGLWHLGLTATNYNCDDPLASFLSPTAFSSSSDLTGSSSQAQLNWRMGTGGWSPADSNAQQWLQMDLGNRVEITAVATQGRYGSSDWVTSYRLMFSDTGHNWQQYKQEDSIWTFVGNMNADSVVHHKLLHSMRTRFVRFVPLGWNPSGKIGMRVEVYGCSYKSDVADFDGRSSLLYRFNQKMMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLALYLNLDDSKARLSSIAPSAILGSLLDDQHWHSVLLERVGKQANFTVDTNTQHFRTKGETDVLDIDYELSFGGIPVPSKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQIYTVGNVTFSCSEPQIVPITFVNSRSSYLLLPGTPQIDGLSVSFQFRTWNRDGLLLSTELSEGSGTLMLMLEGGALRLLIKKVAGQGIEILTGSDLNDGLWHSVSINARRNRVTLTLDNDAASPTPDTSRLQIYSGNSYYFGGCPDNLTESQCLNPIKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLHIDLCSIKDRCLPNYCEHGGHCAQSWTTFDCNCSDTGYTGATCHDSIYEQSCEVYRYRGNKAGFFYVDSDGSGPLGPLQVYCNITEDKIWMTVQHNNTELTRVQGFNSEKPYAMTLNYGGSMEQLEALIDGSEHCEQEVAYHCRRSRLLNTPDGAPFTWWIGRSNEKHPYWGGSVPGVQQCGCGLEESCLDIRHFCNCDADTEEWTKDTGVLSFKDHLPVTQIIITDTNRSNSEAAWRIGPLRCYGDRHYWNAVSFSTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGIKDFIRLEMSSPSEVTFAIDVGNGPVELLVQSLSPLNDNQWHYIRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQLFVGGTSSRQKGFLGCIRSLHLNGQKVDLEERAKVTSGVRPGCPGHCSSYGSNCHNGGKCVEKHSGYSCDCTNSPYEGPFCQKEISAHFDSGSSVTYMFQEPYPVTKNTSLSSSAIYTDTAPSKETITLSFVTAHAPSLLLFVNSSSQDFLAILLCKNGSLQVRYRLSKEESHVFTISTENLANRRVHQVKISREGPELSIQVDQQLFSYNLSPEVEFRTARSLILGKVTETLGLDPEVARANTLGFVGCLSSVQYNHIAPLKAALRHANIAPVTVQGTLTESNCGSMVDSDMNAVTTVHSSSDTFGKTDEREPLTNAVRSDSAVIGGVIAVVTFITFCVIGIMTRFLYQHKQSHRTNQMKEKEYPENLDSSFRNDIDLQNTASECKREYFI", "length": 1306, "header": "tr|A0A9J7K9I1-1|A0A9J7K9I1_CRIGR Isoform 1 of Contactin-associated protein-like 5 isoform X2 OS=Cricetulus griseus OX=10029 GN=Cntnap5 PE=3 SV=1 CANONICAL=A0A9J7K9I1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MYX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9I1/entry#A0A8C2MYX6-1", "sequence": { "sequence": "MDSVPRLTSVLTLMLSGLWHLGLTATNYNCDDPLASFLSPTAFSSSSDLTGSSSQAQLNWRMGTGGWSPADSNAQQWLQMDLGNRVEITAVATQGRYGSSDWVTSYRLMFSDTGHNWQQYKQEDSIWTFVGNMNADSVVHHKLLHSMRTRFVRFVPLGWNPSGKIGMRVEVYGCSYKSDVADFDGRSSLLYRFNQKMMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLALYLNLDDSKARLSSIAPSAILGSLLDDQHWHSVLLERVGKQANFTVDTNTQHFRTKGETDVLDIDYELSFGGIPVPSKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQIYTGNVTFSCSEPQIVPITFVNSRSSYLLLPGTPQIDGLSVSFQFRTWNRDGLLLSTELSEGSGTLMLMLEGGALRLLIKKVAGQGIEILTGSDLNDGLWHSVSINARRNRVTLTLDNDAASPTPDTSRLQIYSGNSYYFGGCPDNLTESQCLNPIKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLHIDLCSIKDRCLPNYCEHGGHCAQSWTTFDCNCSDTGYTGATCHDSIYEQSCEVYRYRGNKAGFFYVDSDGSGPLGPLQVYCNITEDKIWMTVQHNNTELTRVQGFNSEKPYAMTLNYGGSMEQLEALIDGSEHCEQEVAYHCRRSRLLNTPDGAPFTWWIGRSNEKHPYWGGSVPGVQQCGCGLEESCLDIRHFCNCDADTEEWTKDTGVLSFKDHLPVTQIIITDTNRSNSEAAWRIGPLRCYGDRHYWNAVSFSTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGIKDFIRLEMSSPSEVTFAIDVGNGPVELLVQSLSPLNDNQWHYIRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQLFVGGTSSRQKGFLGCIRSLHLNGQKVDLEERAKVTSGVRPGCPGHCSSYGSNCHNGGKCVEKHSGYSCDCTNSPYEGPFCQKEISAHFDSGSSVTYMFQEPYPVTKNTSLSSSAIYTDTAPSKETITLSFVTAHAPSLLLFVNSSSQDFLAILLCKNGSLQVRYRLSKEESHVFTISTENLANRRVHQVKISREGPELSIQVDQQLFSYNLSPEVEFRTARSLILGKVTETLGLDPEVARANTLGFVGCLSSVQYNHIAPLKAALRHANIAPVTVQGTLTESNCGSMVDSDMNAVTTVHSSSDTFGKTDEREPLTNAVRSDSAVIGGVIAVVTFITFCVIGIMTRFLYQHKQSHRTNQMKEKEYPENLDSSFRNDIDLQNTASECKREYFI", "length": 1305, "header": "tr|A0A8C2MYX6-1|A0A8C2MYX6_CRIGR Computationally mapped isoform of Contactin-associated protein-like 5 isoform X3 OS=Cricetulus griseus OX=10029 GN=Cntnap5 PE=3 SV=1 CANONICAL=A0A9J7K9I1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GZ64-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9I1/entry#A0A9J7GZ64-1", "sequence": { "sequence": "MDSVPRLTSVLTLMLSGLWHLGLTATNYNCDDPLASFLSPTAFSSSSDLTGSSSQAQLNWRMGTGGWSPADSNAQQWLQMDLGNRVEITAVATQGRYGSSDWVTSYRLMFSDTGHNWQQYKQEDSIWTFVGNMNADSVVHHKLLHSMRTRFVRFVPLGWNPSGKIGMRVEVYGCSYKSDVADFDGRSSLLYRFNQKMMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLALYLNLDDSKARLSSIAPSAILGSLLDDQHWHSVLLERVGKQANFTVDTNTQHFRTKGETDVLDIDYELSFGGIPVPSKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQIYTGNVTFSCSEPQIVPITFVNSRSSYLLLPGTPQIDGLSVSFQFRTWNRDGLLLSTELSEGSGTLMLMLEGGALRLLIKKVAGQGIEILTGSDLNDGLWHSVSINARRNRVTLTLDNDAASPTPDTSRLQIYSGNSYYFGGCPDNLTESQCLNPIKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLHIDLCSIKDRCLPNYCEHGGHCAQSWTTFDCNCSDTGYTGATCHDSIYEQSCEVYRYRGNKAGFFYVDSDGSGPLGPLQVYCNITEDKIWMTVQHNNTELTRVQGFNSEKPYAMTLNYGGSMEQLEALIDGSEHCEQEVAYHCRRSRLLNTPDGAPFTWWIGRSNEKHPYWGGSVPGVQQCGCGLEESCLDMTKDTGVLSFKDHLPVTQIIITDTNRSNSEAAWRIGPLRCYGDRHYWNAVSFSTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGIKDFIRLEMSSPSEVTFAIDVGNGPVELLVQSLSPLNDNQWHYIRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQLFVGGTSSRQKGFLGCIRSLHLNGQKVDLEERAKVTSGVRPGCPGHCSSYGSNCHNGGKCVEKHSGYSCDCTNSPYEGPFCQKEISAHFDSGSSVTYMFQEPYPVTKNTSLSSSAIYTDTAPSKETITLSFVTAHAPSLLLFVNSSSQDFLAILLCKNGSLQVRYRLSKEESHVFTISTENLANRRVHQVKISREGPELSIQVDQQLFSYNLSPEVEFRTARSLILGKVTETLGLDPEVARANTLGFVGCLSSVQYNHIAPLKAALRHANIAPVTVQGTLTESNCGSMVDSDMNAVTTVHSSSDTFGKTDEREPLTNAVRSDSAVIGGVIAVVTFITFCVIGIMTRFLYQHKQSHRTNQMKEKEYPENLDSSFRNDIDLQNTASECKREYFI", "length": 1292, "header": "tr|A0A9J7GZ64-1|A0A9J7GZ64_CRIGR Computationally mapped isoform of Contactin-associated protein-like 5 isoform X4 OS=Cricetulus griseus OX=10029 GN=Cntnap5 PE=3 SV=1 CANONICAL=A0A9J7K9I1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K9I1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9I1/entry#A0A9J7K9I1-1", "sequence": { "sequence": "MDSVPRLTSVLTLMLSGLWHLGLTATNYNCDDPLASFLSPTAFSSSSDLTGSSSQAQLNWRMGTGGWSPADSNAQQWLQMDLGNRVEITAVATQGRYGSSDWVTSYRLMFSDTGHNWQQYKQEDSIWTFVGNMNADSVVHHKLLHSMRTRFVRFVPLGWNPSGKIGMRVEVYGCSYKSDVADFDGRSSLLYRFNQKMMSTLKDVISLKFKSMQGDGVLFHGEGQRGDHITLELQKGRLALYLNLDDSKARLSSIAPSAILGSLLDDQHWHSVLLERVGKQANFTVDTNTQHFRTKGETDVLDIDYELSFGGIPVPSKPGTFLKKNFHGCIENLYYNGVNIIDLAKRRKHQIYTVGNVTFSCSEPQIVPITFVNSRSSYLLLPGTPQIDGLSVSFQFRTWNRDGLLLSTELSEGSGTLMLMLEGGALRLLIKKVAGQGIEILTGSDLNDGLWHSVSINARRNRVTLTLDNDAASPTPDTSRLQIYSGNSYYFGGCPDNLTESQCLNPIKAFQGCMRLIFIDNQPKDLISVQQGSLGNFSDLHIDLCSIKDRCLPNYCEHGGHCAQSWTTFDCNCSDTGYTGATCHDSIYEQSCEVYRYRGNKAGFFYVDSDGSGPLGPLQVYCNITEDKIWMTVQHNNTELTRVQGFNSEKPYAMTLNYGGSMEQLEALIDGSEHCEQEVAYHCRRSRLLNTPDGAPFTWWIGRSNEKHPYWGGSVPGVQQCGCGLEESCLDIRHFCNCDADTEEWTKDTGVLSFKDHLPVTQIIITDTNRSNSEAAWRIGPLRCYGDRHYWNAVSFSTEASYLHFPTFHAEFSADISFFFKTTALSGVFLENLGIKDFIRLEMSSPSEVTFAIDVGNGPVELLVQSLSPLNDNQWHYIRAERNLKETSLQVDNLPRSTRETSEEGHFRLQLNSQLFVGGTSSRQKGFLGCIRSLHLNGQKVDLEERAKVTSGVRPGCPGHCSSYGSNCHNGGKCVEKHSGYSCDCTNSPYEGPFCQKEISAHFDSGSSVTYMFQEPYPVTKNTSLSSSAIYTDTAPSKETITLSFVTAHAPSLLLFVNSSSQDFLAILLCKNGSLQVRYRLSKEESHVFTISTENLANRRVHQVKISREGPELSIQVDQQLFSYNLSPEVEFRTARSLILGKVTETLGLDPEVARANTLGFVGCLSSVQYNHIAPLKAALRHANIAPVTVQGTLTESNCGSMVDSDMNAVTTVHSSSDTFGKTDEREPLTNAVRSDSAVIGGVIAVVTFITFCVIGIMTRFLYQHKQSHRTNQMKEKEYPENLDSSFRNDIDLQNTASECKREYFI", "length": 1306, "header": "tr|A0A9J7K9I1-1|A0A9J7K9I1_CRIGR Isoform 1 of Contactin-associated protein-like 5 isoform X2 OS=Cricetulus griseus OX=10029 GN=Cntnap5 PE=3 SV=1 CANONICAL=A0A9J7K9I1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 475, "start_aa": "Thr", "end_pos": 475, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr475", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9I1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9I1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9I1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9I1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766518", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766518", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9I1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9I1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9I1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9I1" } ], "pmid": "" }, { "name": "cell junction", "id": "GO:0030054", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030054", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9I1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9I1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1022, "end_pos": 1024, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1058, "end_pos": 1060, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1072, "end_pos": 1074, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1125, "end_pos": 1127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 356, "end_pos": 358, "annotation": "n_glycosylation_sequon" }, { "start_pos": 497, "end_pos": 499, "annotation": "n_glycosylation_sequon" }, { "start_pos": 536, "end_pos": 538, "annotation": "n_glycosylation_sequon" }, { "start_pos": 572, "end_pos": 574, "annotation": "n_glycosylation_sequon" }, { "start_pos": 623, "end_pos": 625, "annotation": "n_glycosylation_sequon" }, { "start_pos": 636, "end_pos": 638, "annotation": "n_glycosylation_sequon" }, { "start_pos": 769, "end_pos": 771, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7K9I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9I1" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 547, "end_pos": 584, "start_aa": "Ile", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7K9I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9I1" }, { "id": "PS50022", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50022" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F5/8 type C", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 174, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7K9I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9I1" }, { "id": "PS51406", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51406" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibrinogen C-terminal", "eco_id": "ECO_0000259", "start_pos": 583, "end_pos": 635, "start_aa": "Cys", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7K9I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9I1" }, { "id": "PS50025", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50025" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Laminin G", "eco_id": "ECO_0000259", "start_pos": 180, "end_pos": 361, "start_aa": "Val", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 475 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1022, "end_pos": 1024 }, { "start_pos": 1058, "end_pos": 1060 }, { "start_pos": 1072, "end_pos": 1074 }, { "start_pos": 1125, "end_pos": 1127 }, { "start_pos": 282, "end_pos": 284 }, { "start_pos": 356, "end_pos": 358 }, { "start_pos": 497, "end_pos": 499 }, { "start_pos": 536, "end_pos": 538 }, { "start_pos": 572, "end_pos": 574 }, { "start_pos": 623, "end_pos": 625 }, { "start_pos": 636, "end_pos": 638 }, { "start_pos": 769, "end_pos": 771 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7K9K0-1", "uniprot_ac": "A0A9J7K9K0", "uniprot_id": "A0A9J7K9K0_CRIGR", "mass": { "chemical_mass": 168114.0, "monoisotopic_mass": 168114.0 }, "refseq": { "ac": "XP_035301238", "name": "pleckstrin homology domain-containing family H member 2 isoform X1", "summary": "", "url": 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:: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035301238", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301238" } ] }, { "annotation": "In the kidney glomerulus may play a role in linking podocyte foot processes to the glomerular basement membrane. May be involved in stabilization of F-actin by attenuating its depolymerization. Can recruit TGFB1I1 from focal adhesions to podocyte lamellipodia.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9K0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9K0#function" }, { "database": "UniProtKB", "id": "ARBA00054898", "url": "https://www.uniprot.org/uniprotkb/ARBA00054898#function" }, { "database": "UniProtKB", "id": "A0A9J7H1K0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1K0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9K0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9K0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Plekhh2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9K0", "locus": {} } ], "crossref": [ { "id": "cd13206", "url": 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"InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019749", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019749", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760655", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760655", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7K9K0", "url": "https://www.orthodb.org/?gene=A0A9J7K9K0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22903", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22903", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22903:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22903:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00373", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00373", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00784", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00784", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21989", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21989", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035301238", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301238", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H1K0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1K0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1K0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1K0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9K0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9K0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9K0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9K0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEISEPEGPVDWKERCVLLESQLMKFRVQASKIRELLAEKMQQLERQVIDAERQAEKAFQQVQVMEEKLKAANIQTSESETRLYKKYQDLESVMQEKDGIIQNLEFRLEEQKQVRIQEAKIIEEKAAKIKEWVTVKLNELEVENQNLRFINQAQTEEIRAIQSKLQELQGKKVSCVSTPKLSEGQNLSSLTFGCFLSRAKSPSHVVRSEEISKMACKEPEFTEEKCIEEMEIAEKPADNQVQENRSQRKLHETPCSSEPNRKTRASFATDGGTSQNSGAPASDWSSDEEDQSKGRSKSRCTSILSSHTSEEGVQCDRMGSEAYLTASDDSSSIFEEEAFGVSRPEPKKLYSWQQKAPWKAQNSLAKGNSQAGIKEQDSSSDELNKKFQSQRLDYSSSSSEANTPSPILTPALTPKHPNSLPRKGTQLVPPVYLPPPKLRIPNVFSISVALTKRHLSQPQLCSDRMFGMNRNAISMIRPLRPQETDLDVVDGDGLEVVESMDTGCDDRLFSYDSLDSPNADDQETSEPTKKASCSKPPTPPLHRFPSWESRIYAVAKSGIRMSEVFNMENANENSATILSYSASGLYTSLLYKNMTIPVYTTLKGKATQISSSPFLDDSSGSEEEDSSRCSSRTSESDTRNRSGPSSPRAMKRGVSVSSMASESDYAIPPDAYCIDSECSQPEQKLPKTCSSSSENGKNELLEKSGYLLKMSGKVKTWKRRWFVLKGGELLYYKSPSDVIRKPQGHIELNASCSIIRGNNKQTVQLTTEKHTYYLTADSPNLLEEWIKVLQNVLRVQAANPLCLQPEGKPTAKGLLTKVKHGYSKRVWCMIVGKTLYYFRSQEDKFPLGQIKLWEAKVEEVDRSCDSDEDYEASGRCLLSTHYTIVIHPKDQGPTYLLIGSKHEKDTWLYHLTVAAGSNNVNVGSEFEQLVFKLLNIEGEPSSQIWRHPMLCHSKEGILSPLTTLPSEALQTEAIKLFKTCQLFINAAVDSPAIDYHISLAQSALQVCLTHPELQNEIFCQLIKQTRRRQPQNQQGPLQGWQLLALCVGLFLPHHPFLWLLQLHLKRNADSRTEFGKYAIYCQRCVERTQQNGDREARPSRMEILSTLLRNPYHHSLPFSIPVHFMNGIYQVVGFDASTTVEEFLNTLNQDTGMRKPAQSGFALFTDDPSGRDLEHCLQGNIKICDIISKWEQASKEQQSGKCEGTRTVRLTYKNRLYFSVQTRGETDREKLLLLYQTNDQIINGLFPLNKDLALEMAALLAQVEIGDFERPFSTPAGHVTNQCKASQNLKQVIEKFYPKRYRDSCSEEQLRQLYQRLSTRWMALRGHNAADCVRIYLTVARKWPFFGAKLFFAKPIAPSLSGNIFVWLAIHENGLSILEYTSMRLMVSYVYKSLMTFGGCQDDFMVVINTHSKDRPTEKLLFAMAKPKILEITLLIASYINNSYQQKAFHHLSAPALLSARTQEPPARAMGSQPLPSNSRPSKGPTLL", 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"length": 1188, "header": "tr|A0A9J7H1K0-1|A0A9J7H1K0_CRIGR Computationally mapped isoform of Pleckstrin homology domain-containing family H member 2 OS=Cricetulus griseus OX=10029 GN=Plekhh2 PE=4 SV=1 CANONICAL=A0A9J7K9K0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K9K0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9K0/entry#A0A9J7K9K0-1", "sequence": { "sequence": "MAEISEPEGPVDWKERCVLLESQLMKFRVQASKIRELLAEKMQQLERQVIDAERQAEKAFQQVQVMEEKLKAANIQTSESETRLYKKYQDLESVMQEKDGIIQNLEFRLEEQKQVRIQEAKIIEEKAAKIKEWVTVKLNELEVENQNLRFINQAQTEEIRAIQSKLQELQGKKVSCVSTPKLSEGQNLSSLTFGCFLSRAKSPSHVVRSEEISKMACKEPEFTEEKCIEEMEIAEKPADNQVQENRSQRKLHETPCSSEPNRKTRASFATDGGTSQNSGAPASDWSSDEEDQSKGRSKSRCTSILSSHTSEEGVQCDRMGSEAYLTASDDSSSIFEEEAFGVSRPEPKKLYSWQQKAPWKAQNSLAKGNSQAGIKEQDSSSDELNKKFQSQRLDYSSSSSEANTPSPILTPALTPKHPNSLPRKGTQLVPPVYLPPPKLRIPNVFSISVALTKRHLSQPQLCSDRMFGMNRNAISMIRPLRPQETDLDVVDGDGLEVVESMDTGCDDRLFSYDSLDSPNADDQETSEPTKKASCSKPPTPPLHRFPSWESRIYAVAKSGIRMSEVFNMENANENSATILSYSASGLYTSLLYKNMTIPVYTTLKGKATQISSSPFLDDSSGSEEEDSSRCSSRTSESDTRNRSGPSSPRAMKRGVSVSSMASESDYAIPPDAYCIDSECSQPEQKLPKTCSSSSENGKNELLEKSGYLLKMSGKVKTWKRRWFVLKGGELLYYKSPSDVIRKPQGHIELNASCSIIRGNNKQTVQLTTEKHTYYLTADSPNLLEEWIKVLQNVLRVQAANPLCLQPEGKPTAKGLLTKVKHGYSKRVWCMIVGKTLYYFRSQEDKFPLGQIKLWEAKVEEVDRSCDSDEDYEASGRCLLSTHYTIVIHPKDQGPTYLLIGSKHEKDTWLYHLTVAAGSNNVNVGSEFEQLVFKLLNIEGEPSSQIWRHPMLCHSKEGILSPLTTLPSEALQTEAIKLFKTCQLFINAAVDSPAIDYHISLAQSALQVCLTHPELQNEIFCQLIKQTRRRQPQNQQGPLQGWQLLALCVGLFLPHHPFLWLLQLHLKRNADSRTEFGKYAIYCQRCVERTQQNGDREARPSRMEILSTLLRNPYHHSLPFSIPVHFMNGIYQVVGFDASTTVEEFLNTLNQDTGMRKPAQSGFALFTDDPSGRDLEHCLQGNIKICDIISKWEQASKEQQSGKCEGTRTVRLTYKNRLYFSVQTRGETDREKLLLLYQTNDQIINGLFPLNKDLALEMAALLAQVEIGDFERPFSTPAGHVTNQCKASQNLKQVIEKFYPKRYRDSCSEEQLRQLYQRLSTRWMALRGHNAADCVRIYLTVARKWPFFGAKLFFAKPIAPSLSGNIFVWLAIHENGLSILEYTSMRLMVSYVYKSLMTFGGCQDDFMVVINTHSKDRPTEKLLFAMAKPKILEITLLIASYINNSYQQKAFHHLSAPALLSARTQEPPARAMGSQPLPSNSRPSKGPTLL", "length": 1489, "header": "tr|A0A9J7K9K0-1|A0A9J7K9K0_CRIGR Isoform 1 of Pleckstrin homology domain-containing family H member 2 OS=Cricetulus griseus OX=10029 GN=Plekhh2 PE=4 SV=1 CANONICAL=A0A9J7K9K0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 539, "start_aa": "Thr", "end_pos": 539, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr539", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9K0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9K0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9K0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9K0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760655", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760655", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of actin filament depolymerization", "id": "GO:0030835", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030835", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9K0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9K0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9K0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9K0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9K0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9K0" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9K0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9K0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9K0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9K0" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", 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Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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OS=Cricetulus griseus OX=10029 GN=LOC100761617 PE=3 SV=1 CANONICAL=A0A9J7K9K4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9K4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9K4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9K4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9K4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761617", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761617", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9K4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9K4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9K4", "url": 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"sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7K9Q2-1", "uniprot_ac": "A0A9J7K9Q2", "uniprot_id": "A0A9J7K9Q2_CRIGR", "mass": { "chemical_mass": 22388.0, "monoisotopic_mass": 22388.0 }, "refseq": { "ac": "XP_035301565", "name": "LOW QUALITY PROTEIN: major histocompatibility complex class I-related gene protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301565" }, "gene_names": [ { "name": "LOC100753615", "type": "recommended", "evidence": [ { "id": "A0A9J7K9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9Q2" } ] }, { "name": "LOC100753615", "type": "synonym", "evidence": [ { "id": "XP_035301565", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301565" } ] } ], "protein_names": [ { "name": "LOW QUALITY PROTEIN: major histocompatibility complex class I-related gene protein", "type": "synonym", "evidence": [ { "id": "XP_035301565", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301565" }, { "id": "A0A9J7K9Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9Q2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035301565", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301565" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9Q2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9Q2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100753615", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9Q2", "locus": {} } ], "crossref": [ { "id": "A0A9J7K9Q2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7K9Q2", "database": "AlphaFoldDB", "categories": [] }, { "id": "100753615", "url": "https://www.ncbi.nlm.nih.gov/gene/100753615", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001039", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001039", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050208", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050208", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753615", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753615", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7K9Q2", "url": "https://www.orthodb.org/?gene=A0A9J7K9Q2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16675", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16675", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16675:SF242", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16675:SF242", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00129", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00129", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035301565", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301565", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7K9Q2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9Q2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9Q2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMGCKLLEDSSTTGFLQYASDGQDFIISNKDALSWVAVDNNVAHISKQAWEVNLQELQYQKNWLEEECIAWLKRFLEYGKDTLERTESESILLTVKVISGPIILTIVLAGAGVLTWRRSREQEEVIYHPTKSAGTALPFRRAPTCPLSGVSAMHLTQWGLRELSICDKKTGATNFSLFFGSRKAVNFQALDGLLYHSRL", "length": 199, "header": "tr|A0A9J7K9Q2-1|A0A9J7K9Q2_CRIGR Isoform 1 of LOW QUALITY PROTEIN: major histocompatibility complex class I-related gene protein OS=Cricetulus griseus OX=10029 GN=LOC100753615 PE=3 SV=1 CANONICAL=A0A9J7K9Q2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7K9Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9Q2/entry#A0A9J7K9Q2-1", "sequence": { "sequence": "MMGCKLLEDSSTTGFLQYASDGQDFIISNKDALSWVAVDNNVAHISKQAWEVNLQELQYQKNWLEEECIAWLKRFLEYGKDTLERTESESILLTVKVISGPIILTIVLAGAGVLTWRRSREQEEVIYHPTKSAGTALPFRRAPTCPLSGVSAMHLTQWGLRELSICDKKTGATNFSLFFGSRKAVNFQALDGLLYHSRL", "length": 199, "header": "tr|A0A9J7K9Q2-1|A0A9J7K9Q2_CRIGR Isoform 1 of LOW QUALITY PROTEIN: major histocompatibility complex class I-related gene protein OS=Cricetulus griseus OX=10029 GN=LOC100753615 PE=3 SV=1 CANONICAL=A0A9J7K9Q2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"url": "https://www.uniprot.org/uniprotkb/A0A9J7K9Q2" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9Q2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9Q2" } ], "pmid": "" }, { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9Q2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9Q2" } ], "pmid": "" }, { "name": "late endosome membrane", "id": "GO:0031902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031902", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9Q2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9Q2" } ], "pmid": "" }, { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9Q2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9Q2" } ], "pmid": "" }, { "name": "MHC class I protein complex", "id": "GO:0042612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042612", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9Q2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9Q2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9Q2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9Q2" } ], "pmid": "" }, { "name": "antigen processing and presentation of peptide antigen via MHC class I", "id": "GO:0002474", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002474", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9Q2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9Q2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 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computational analysis. This record is derived from a genomic sequence (NC_048603.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305533", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305533" } ] }, { "annotation": "Component of hair-cell stereocilia coat. Required for normal hearing.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9R3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9R3#function" }, { "database": "UniProtKB", "id": "ARBA00057100", "url": "https://www.uniprot.org/uniprotkb/ARBA00057100#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9R3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9R3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pkhd1l1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9R3", "locus": {} } ], "crossref": [ { "id": "cd00102", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00102", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00603", "url": 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Classification" ] }, { "id": "IPR012334", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012334", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019316", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019316", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037524", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037524", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055401", "database": 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"Other" ] }, { "id": "PF10162", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10162", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24606", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24606", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305533", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305533", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7K9R3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9R3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9R3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9R3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGHLWLSGTWFLSGLLVCAADPGTDGPETTPKVTEVIPKYGSVNGATRLTIKGEGFSQANQFNYGADNPALGNHVQLVSSLQSITCDVEKDSSHSTQITCYTRAMPEDTYTVRVSVDGVPIAEKNTCKGLTSSRACSFSAKSFRTPTIRSITPLSGTPGTLITIQGRLFTDVYGSNTALSSNGRNVRILRVYIGGMPCELLHPHSDDLYGLRLDQPNGDIGSVTCKTTGTYIGHHNVSFILDSDYGRSFPEKMTYFVSSLNKISMFQTYAEVTMTSPSKGSTQGGTALTIHGRFFDQTDLPVRVLVGGQACDILNVTENTIYCKTPPRPEILKTLYPGGRGLKLEVWNNSRPVHLEEIFEYNEHTPGYMGASWLDSASYVWPMEQDTFVARFSGFLVPPDSDVYRFYIRGDDRYAIYFSQTGRPEDKVRIAYHSANANSYYSSSTQRSDEIYLQKGKAYYIEILLQEYTLSAFVDVGLYQYNNVFTEQQTGDAVNEEQVIKSQSTVIPEVQIITLENWETTNATHEIQQVAVSSPCVGTNSCSLSQYRFIYNMEKTVWLPADASDFTLQSALNELWSIKPDSVQVTSERDLQRSIYTVTFMSTRGDFDLLGYEVFEGNNVTLDITEQTRGKPSLETFTLNWDGIASTPLAPESSEAEFQEAVQEMVSAKCAPEISNLEEGFLVKYFRDYETDFDLDHINRGQKSSETDAYCGRYSLKNPAVLFDSADVKPNKLPYGDILLFPYNQLCLAYKGSLANYLGLKFKYQDSGNVIRSADIQFEYNFSSGNQWTYTCIDLLDFLQTKYAGTSFSLQRISLQKSSEFQPIYVDAVYIGQTPTVSALGEMPKRRPPALANKGIFLKYFQVNKTKVNGSAMGIQYSVSMTSYNCSHNIPMMAVSFAQIITNETKDESVYRGNNWPGESKIRIQKIHEASPPISGSFDIQAYGHTLKGILAAVSASDLQFALQSLEDIGRVSVRREGTCAGHTWTIEWKSPCGRQPLLQINDSNIIGEKANVTVTKTKEGGLFRQRIPGDMLRTPNQQPQVEVYVNGIPAKCSGDCGFTWDPMTTPLVLTTTPSEGSYAESTILTIAGSGFSSTSAVSVSVGSTSCSLLSVDENEIKCQILNGSAGHAPVLVSIADAGLAQNLEGEGSTFVYRSQISHVWPDSGSLAGGTLLTVSGFGFSENSTVLVGNETCNVIEGDLNTITCRTSKRIEGTVDISVITNGIQATAKDSFSYNCLQTPVITDFSPKERAVWGDINLAIKGYNFGNELAQNMVYVGGKACQVLQSNFTDISCLLPKLPPGKHDIHVNVRNWGLASTRNKLNASIWYVLEVTHLFPQRGSLYGGTELTIKGLGFSTVPTENSVFLGSFPCDITSSSEDVIKCTLHSTGTVFRITNNGSHLEHGLGYAWSPSILNVTVGDTVVWHWQAHPFLRSIGYRVFSVSSPGSVTYDGKGFINGRQKSASGSFSYQFTSPGIHYYSSGYVDDIHSISLQGVINVLPAETRRIPLHLFVGNTEAMYAPAGPENLHWTSTAASCLATEPLCGLNDTNAKNPNQLLFELSSCVSPSISNVTPSAGTVNELITISGHGFSSLACANKVTVGGYPCVVEESSESSIICHIDPQNSMDVGIREIVTLIVYNLGTAINTAPGEFDRRFVLLPNIDMVLPNEGSTTGMTRVTIQGSGFVVSSSNVEVFMGDFPCKVLTVTYTTIECETSPAPQQLALVDLLIHGIPAQCQGNCSFSYLESIAPCVTRVSPNSIKGSVHVLIEGEGFGTVLEEVSIFIGSQQFSAIEVTENNITALITPLAAGLHSLSVVVGSKGLALGNVTVSSPTLASLSPTSGSIAGGTTLTITGNGFSPGNTTVTVGNKPCQIVFINSSEVYCSTPAGRAGTTNLKISVNEVVYSPLSFTYTMEDTPFLKGIVPNRGPPGTEVEITGSNLGFDISDVSVMIKDSACNVTSVNDSMLQCIVGEHAGGIFPVTMLHKTKGSALSSVLFEYPLYIQDIYPKQGSFGGGQTMTVTGTGFDPQNSALLVCGSQCAVDKLGSDSKTLFCEIPPNNGSGPDQACGVSVVNGKDSSQSTMPFTYSLSLTPLVTEISPRRGSTAGGTRLTVTGSGFSENTRDVHVSIANDQCDVQYSNKTHIICVTSPHVPSGWAPVHISIRNFGMAKVENPDFLYVDVWSSNASWGGKPPPEEGSLAVITEGQIILLDQSTPILKMLLIQGGTLIFDEADIELQAENILITDGGVLQIGTEASPFQHQAVITLHGHLRSPELPVYGAKTLAVREGTLDLHGLPVPVVWTRLAHTANAGEWTLIVQEAVTWKAGDSIVIASTGHRHSQGENEKRTIASVSADGMHITLTRPLNYTHLGITVTLPDGTVFEARAEVGILTRNILIRGSDNVEWNDKIPSCPDGFDTGEFATQTCLQGKFGEEIGSDQFGGCIMLHAPLPGANMVTGRIEYVEVFHAGQSFRLGRYPIHWHLLGDLQFKSYVRGCAIHQAYNRAVTIHNTHHLLVERNIIYDIKGGAFFIEDGIEHGNILQYNLAIFVQQSTSLLNDDVTPAAFWVTNPNNTIRHNVAAGGTHFGFWYRMNNHPDGPSYDRNICQKRIPLGEFSNNTVHSQGWFGLWIFEEYFPMQTGSCTSTMPVPAVFNSLTVWNCQKGAEWVNGGALQFHNFVVVNNYEAGIETKRIVASYVGGWGETNGAVIKNAKIVGHLDELGMGSAFCTSKGLVLPFSQGLTVSSVRFMNFDRQDCVALGVTSITGVCNDRCGGWSTKFVDIQYFHAPNKAGFRWEHEAVLIDVDGSLTGHRGHTVIPHSSLLDPSHCTQEAEWSFGFPGSICDASVSFHRLAFNKPSPVSLLEKDVVLSDSFGTSIVPFQKKRLTHMSGWMALIPNANHINWYFRGAEHLTNISYTSTFYGFKEEDYVIISHNFTQNPDVFNVVDMRNGSSNPLNWNTSKNGDWHLEVNTSTLYYLVSGRSDLPQSQPIPGTLDPDAKDVIINFQAYCCVLQDCFPVHPPSRKPMPRTRPASYNLWSNESFWQSSPENNYTIPHPGANVVIPEGSWIVADTDIPPMEKLIIWGVLELEDRSEVESATPSYRKVVLNATYISVQGGRLIGGWEDNPFKGELQIVLRGNHSTPEWAFPEGPNQGAKVLGVFGELDLHGLPHSVYKTKLSETAEAGSRILSLMDAVDWQEGEDIVITTTSYDLHQTETRRIAKILHGHKILVLNDTLSYTHLAERQQIPETGQTYTLAADVGLLSRNIKIFGEDYPGWSKDSFGARILVGSLTGNTVTFKGNARISNVEFYHSGQEGFRDSTDPRYSVTFLNLGQVQEHGLSYVRGCAFHHGFSPAIGVFGTDGLDIDDNIIHFTVGEGIRIWGDANRVRGNLVTLSVWPGTYQNRKDLSSTLWHAAIEVNRGTNTVLQNNVVAGFGRVGYRIDGEPCSRQANPMENWFDNEAHGGLYGIYMNQDGLPGCSLIQGFTIWTCWDYGIYFQTTESVHIYNVTLVNNGMGIFPMIYTPPSVSHKISSKTVKIKNSLIVGSSPEFNCSDVLTNDSPDVELTSAHRSSRPPSGGRGGICWPTFASAHNMAPRKPHAGIMSYNAISGLLDVSGSTFVGFKDVCSGETNVIFITNPLNEDLQHPIHVKNVQLLDTTEQSKVFIHRPDISKVNPSDCVDMVCDAKRKSLLRDMDGSFLGSSGSVIPQAEYEWDGNSRLGIGDYRIPKAMLTFLNGSRIPIAEKAPHKGIIRDSTCKYISAWQSYRCSGMEYAMLVIESLDSDTETRRLSPVAIMSNGYVDLINGPQDHGWCAGYTCQRRLSLFHSIVALNKMYEVYFTGTSPQNLRLMLLNVEHNKAVLVGIFFSTLQRLDVYVNNSLVCPKNTAWNAQKRFCELDRHLNAEQLLPNLGSTTPGENYFDRNYQTLYILVKGTTPVEVHTATVIFVSFQLPAVTEDDFFSSRNLVRNLALFLKIPNDKIRVSRIIGVSLRRKRSTGRVMELEIGAAPARFLQNSTTGQMQLSELQEISGTLGQAVILGKISTVLGFNISSMSITSPIPQPTDSGWVKVTAQPVERSAFPVHYLAFVSSLSLVAQPVAAQPGQPFPQQPSVKAVDHEGNCVSVGITSLTLKALLKDSNNNQVGGLGGNTTIPFSNCWANYTDLTLHRTGKNYKIEFVLDNTVRVESRTFSLSAQTVPGGGGSSPSSGGSGGHSKAAALATPFQTLIVVTGCLVGRLLLLEVFTAAVFILNTTIGSSSSAY", "length": 4252, "header": "tr|A0A9J7K9R3-1|A0A9J7K9R3_CRIGR Isoform 1 of Fibrocystin-L OS=Cricetulus griseus OX=10029 GN=Pkhd1l1 PE=4 SV=1 CANONICAL=A0A9J7K9R3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7K9R3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9R3/entry#A0A9J7K9R3-1", "sequence": { "sequence": "MGHLWLSGTWFLSGLLVCAADPGTDGPETTPKVTEVIPKYGSVNGATRLTIKGEGFSQANQFNYGADNPALGNHVQLVSSLQSITCDVEKDSSHSTQITCYTRAMPEDTYTVRVSVDGVPIAEKNTCKGLTSSRACSFSAKSFRTPTIRSITPLSGTPGTLITIQGRLFTDVYGSNTALSSNGRNVRILRVYIGGMPCELLHPHSDDLYGLRLDQPNGDIGSVTCKTTGTYIGHHNVSFILDSDYGRSFPEKMTYFVSSLNKISMFQTYAEVTMTSPSKGSTQGGTALTIHGRFFDQTDLPVRVLVGGQACDILNVTENTIYCKTPPRPEILKTLYPGGRGLKLEVWNNSRPVHLEEIFEYNEHTPGYMGASWLDSASYVWPMEQDTFVARFSGFLVPPDSDVYRFYIRGDDRYAIYFSQTGRPEDKVRIAYHSANANSYYSSSTQRSDEIYLQKGKAYYIEILLQEYTLSAFVDVGLYQYNNVFTEQQTGDAVNEEQVIKSQSTVIPEVQIITLENWETTNATHEIQQVAVSSPCVGTNSCSLSQYRFIYNMEKTVWLPADASDFTLQSALNELWSIKPDSVQVTSERDLQRSIYTVTFMSTRGDFDLLGYEVFEGNNVTLDITEQTRGKPSLETFTLNWDGIASTPLAPESSEAEFQEAVQEMVSAKCAPEISNLEEGFLVKYFRDYETDFDLDHINRGQKSSETDAYCGRYSLKNPAVLFDSADVKPNKLPYGDILLFPYNQLCLAYKGSLANYLGLKFKYQDSGNVIRSADIQFEYNFSSGNQWTYTCIDLLDFLQTKYAGTSFSLQRISLQKSSEFQPIYVDAVYIGQTPTVSALGEMPKRRPPALANKGIFLKYFQVNKTKVNGSAMGIQYSVSMTSYNCSHNIPMMAVSFAQIITNETKDESVYRGNNWPGESKIRIQKIHEASPPISGSFDIQAYGHTLKGILAAVSASDLQFALQSLEDIGRVSVRREGTCAGHTWTIEWKSPCGRQPLLQINDSNIIGEKANVTVTKTKEGGLFRQRIPGDMLRTPNQQPQVEVYVNGIPAKCSGDCGFTWDPMTTPLVLTTTPSEGSYAESTILTIAGSGFSSTSAVSVSVGSTSCSLLSVDENEIKCQILNGSAGHAPVLVSIADAGLAQNLEGEGSTFVYRSQISHVWPDSGSLAGGTLLTVSGFGFSENSTVLVGNETCNVIEGDLNTITCRTSKRIEGTVDISVITNGIQATAKDSFSYNCLQTPVITDFSPKERAVWGDINLAIKGYNFGNELAQNMVYVGGKACQVLQSNFTDISCLLPKLPPGKHDIHVNVRNWGLASTRNKLNASIWYVLEVTHLFPQRGSLYGGTELTIKGLGFSTVPTENSVFLGSFPCDITSSSEDVIKCTLHSTGTVFRITNNGSHLEHGLGYAWSPSILNVTVGDTVVWHWQAHPFLRSIGYRVFSVSSPGSVTYDGKGFINGRQKSASGSFSYQFTSPGIHYYSSGYVDDIHSISLQGVINVLPAETRRIPLHLFVGNTEAMYAPAGPENLHWTSTAASCLATEPLCGLNDTNAKNPNQLLFELSSCVSPSISNVTPSAGTVNELITISGHGFSSLACANKVTVGGYPCVVEESSESSIICHIDPQNSMDVGIREIVTLIVYNLGTAINTAPGEFDRRFVLLPNIDMVLPNEGSTTGMTRVTIQGSGFVVSSSNVEVFMGDFPCKVLTVTYTTIECETSPAPQQLALVDLLIHGIPAQCQGNCSFSYLESIAPCVTRVSPNSIKGSVHVLIEGEGFGTVLEEVSIFIGSQQFSAIEVTENNITALITPLAAGLHSLSVVVGSKGLALGNVTVSSPTLASLSPTSGSIAGGTTLTITGNGFSPGNTTVTVGNKPCQIVFINSSEVYCSTPAGRAGTTNLKISVNEVVYSPLSFTYTMEDTPFLKGIVPNRGPPGTEVEITGSNLGFDISDVSVMIKDSACNVTSVNDSMLQCIVGEHAGGIFPVTMLHKTKGSALSSVLFEYPLYIQDIYPKQGSFGGGQTMTVTGTGFDPQNSALLVCGSQCAVDKLGSDSKTLFCEIPPNNGSGPDQACGVSVVNGKDSSQSTMPFTYSLSLTPLVTEISPRRGSTAGGTRLTVTGSGFSENTRDVHVSIANDQCDVQYSNKTHIICVTSPHVPSGWAPVHISIRNFGMAKVENPDFLYVDVWSSNASWGGKPPPEEGSLAVITEGQIILLDQSTPILKMLLIQGGTLIFDEADIELQAENILITDGGVLQIGTEASPFQHQAVITLHGHLRSPELPVYGAKTLAVREGTLDLHGLPVPVVWTRLAHTANAGEWTLIVQEAVTWKAGDSIVIASTGHRHSQGENEKRTIASVSADGMHITLTRPLNYTHLGITVTLPDGTVFEARAEVGILTRNILIRGSDNVEWNDKIPSCPDGFDTGEFATQTCLQGKFGEEIGSDQFGGCIMLHAPLPGANMVTGRIEYVEVFHAGQSFRLGRYPIHWHLLGDLQFKSYVRGCAIHQAYNRAVTIHNTHHLLVERNIIYDIKGGAFFIEDGIEHGNILQYNLAIFVQQSTSLLNDDVTPAAFWVTNPNNTIRHNVAAGGTHFGFWYRMNNHPDGPSYDRNICQKRIPLGEFSNNTVHSQGWFGLWIFEEYFPMQTGSCTSTMPVPAVFNSLTVWNCQKGAEWVNGGALQFHNFVVVNNYEAGIETKRIVASYVGGWGETNGAVIKNAKIVGHLDELGMGSAFCTSKGLVLPFSQGLTVSSVRFMNFDRQDCVALGVTSITGVCNDRCGGWSTKFVDIQYFHAPNKAGFRWEHEAVLIDVDGSLTGHRGHTVIPHSSLLDPSHCTQEAEWSFGFPGSICDASVSFHRLAFNKPSPVSLLEKDVVLSDSFGTSIVPFQKKRLTHMSGWMALIPNANHINWYFRGAEHLTNISYTSTFYGFKEEDYVIISHNFTQNPDVFNVVDMRNGSSNPLNWNTSKNGDWHLEVNTSTLYYLVSGRSDLPQSQPIPGTLDPDAKDVIINFQAYCCVLQDCFPVHPPSRKPMPRTRPASYNLWSNESFWQSSPENNYTIPHPGANVVIPEGSWIVADTDIPPMEKLIIWGVLELEDRSEVESATPSYRKVVLNATYISVQGGRLIGGWEDNPFKGELQIVLRGNHSTPEWAFPEGPNQGAKVLGVFGELDLHGLPHSVYKTKLSETAEAGSRILSLMDAVDWQEGEDIVITTTSYDLHQTETRRIAKILHGHKILVLNDTLSYTHLAERQQIPETGQTYTLAADVGLLSRNIKIFGEDYPGWSKDSFGARILVGSLTGNTVTFKGNARISNVEFYHSGQEGFRDSTDPRYSVTFLNLGQVQEHGLSYVRGCAFHHGFSPAIGVFGTDGLDIDDNIIHFTVGEGIRIWGDANRVRGNLVTLSVWPGTYQNRKDLSSTLWHAAIEVNRGTNTVLQNNVVAGFGRVGYRIDGEPCSRQANPMENWFDNEAHGGLYGIYMNQDGLPGCSLIQGFTIWTCWDYGIYFQTTESVHIYNVTLVNNGMGIFPMIYTPPSVSHKISSKTVKIKNSLIVGSSPEFNCSDVLTNDSPDVELTSAHRSSRPPSGGRGGICWPTFASAHNMAPRKPHAGIMSYNAISGLLDVSGSTFVGFKDVCSGETNVIFITNPLNEDLQHPIHVKNVQLLDTTEQSKVFIHRPDISKVNPSDCVDMVCDAKRKSLLRDMDGSFLGSSGSVIPQAEYEWDGNSRLGIGDYRIPKAMLTFLNGSRIPIAEKAPHKGIIRDSTCKYISAWQSYRCSGMEYAMLVIESLDSDTETRRLSPVAIMSNGYVDLINGPQDHGWCAGYTCQRRLSLFHSIVALNKMYEVYFTGTSPQNLRLMLLNVEHNKAVLVGIFFSTLQRLDVYVNNSLVCPKNTAWNAQKRFCELDRHLNAEQLLPNLGSTTPGENYFDRNYQTLYILVKGTTPVEVHTATVIFVSFQLPAVTEDDFFSSRNLVRNLALFLKIPNDKIRVSRIIGVSLRRKRSTGRVMELEIGAAPARFLQNSTTGQMQLSELQEISGTLGQAVILGKISTVLGFNISSMSITSPIPQPTDSGWVKVTAQPVERSAFPVHYLAFVSSLSLVAQPVAAQPGQPFPQQPSVKAVDHEGNCVSVGITSLTLKALLKDSNNNQVGGLGGNTTIPFSNCWANYTDLTLHRTGKNYKIEFVLDNTVRVESRTFSLSAQTVPGGGGSSPSSGGSGGHSKAAALATPFQTLIVVTGCLVGRLLLLEVFTAAVFILNTTIGSSSSAY", "length": 4252, "header": "tr|A0A9J7K9R3-1|A0A9J7K9R3_CRIGR Isoform 1 of Fibrocystin-L OS=Cricetulus griseus OX=10029 GN=Pkhd1l1 PE=4 SV=1 CANONICAL=A0A9J7K9R3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 157, "start_aa": "Thr", "end_pos": 157, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr157", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3092, "start_aa": "Thr", "end_pos": 3092, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3092", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9R3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9R3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9R3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9R3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768621", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768621", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "stereocilium membrane", "id": "GO:0060171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060171", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9R3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9R3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1002, "end_pos": 1004, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1012, "end_pos": 1014, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1123, "end_pos": 1125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1183, "end_pos": 1185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1190, "end_pos": 1192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1287, "end_pos": 1289, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1322, "end_pos": 1324, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1396, "end_pos": 1398, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1414, "end_pos": 1416, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1545, "end_pos": 1547, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1569, "end_pos": 1571, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1737, "end_pos": 1739, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1796, "end_pos": 1798, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1824, "end_pos": 1826, "annotation": "n_glycosylation_sequon" 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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"MLLRGDCLGKTSVNGVCCCCSALRPRYKRLVDNIFPEDPKDGLVKADMEKLTFYAVSAPEKLDRIGAYLAERLSRDVVRHRSGYVLIAMEALDQLLMACHSQSIKPFVESFLHMVAKLLESGEPKLQVLGTNSFVKFANIEEDTPSYHRRYDFFVSRFSAMCHSCHSDPEIRTEIRIAGIRGIQGVVRKTVNDELRATIWEPQHMDKIVPSLLFNMQKVEEADSRLGPPSSPSAADKEENPAVLAESCFRELLGRATFGNMNNAVRPVFAHLDHHKLWDPNEFAVHCFKIIMYSIQAQYSHHVIQEILGHLDARKKDSPRVRAGIIQVLLEAVAIAAKGSIGPTVLEVFNTLLKHLRLSVELEANDPQRGSMGSIAVSSKDNDEKIVQNAIIQTIGFFGSNLPDYQRSEIMMFIMGKVPVFGTSTHALDVSQLGDLGTRRIQIMLLRSLLMVTSGYKAKTIVTALPGSFLDPLLSPSLMEDYELRQLVLEVMHNLMDRHDNRAKLRGIRIIPDVADLKIKREKICRQDTSFMKKNGQQLYRHIYLGCKEEDNVQKNYELLYTSLALITIELANEEVVIDLIRLAIALQDSAIVNEDNLSMFHRCGIMALVAAYLNFVSQMIAVPAFCQHASKVIETRTMEAPYFLPEHIFRDKCMLPKSLEKHDKSLYFLTNKIAESLGGSGYSVERLSVPYVPQVTDEDRLSRRKSIVDTVSIQVDILSNSVPSDDVVSNTEEITFEALKKAIDTNGMEEQEKEKRRLVIEKFQKAPFEEIAAQCESKANLLHDRLAQILELTIRPPPSPSGTLTITSGHAQYQSVPVYEMKFPDLCVY", "length": 830, "header": "tr|A0A9J7K9S2-1|A0A9J7K9S2_CRIGR Isoform 1 of Protein EFR3 homolog A OS=Cricetulus griseus OX=10029 GN=LOC103158858 PE=3 SV=1 CANONICAL=A0A9J7K9S2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 344, "start_aa": "Thr", "end_pos": 344, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr344", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9S2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:103158858", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103158858", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9S2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9S2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9S2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 597, "end_pos": 599, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 344 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 597, "end_pos": 599 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": 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"other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 822, "start_aa": "Thr", "end_pos": 822, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr822", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9T0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9T0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9T0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9T0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100772869", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772869", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9T0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9T0" } ], "pmid": "" }, { "name": "collagen type IV trimer", "id": "GO:0005587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005587", "evidence": [ { "database": "UniProtKB", "id": 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"length": 1010, "header": "tr|A0A9J7K9V1-1|A0A9J7K9V1_CRIGR Isoform 1 of Ras and Rab interactor 3 OS=Cricetulus griseus OX=10029 GN=Rin3 PE=3 SV=1 CANONICAL=A0A9J7K9V1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9V1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9V1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752649", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752649", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9V1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V1" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9V1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V1" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9V1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9V1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V1" } ], "pmid": "" }, { "name": "endocytic vesicle", "id": "GO:0030139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030139", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9V1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", 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ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035301602", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301602" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9V2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Kcnh1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V2", "locus": {} } ], "crossref": [ { "id": "A0A9J7K9V2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7K9V2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00038", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00038", "database": "CDD", "categories": [ "Protein Classification" ] }, 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"database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035301602", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301602", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7H283", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H283", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H283-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H283-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9V2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9V2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTMAGGRRGLVAPQNTFLENIVRRSNDTNFVLGNAQIVDWPIVYSNDGFCKLSGYHRAEVMQKSSACSFMYGELTDKDTIEKVRQTFENYEMNSFEILMYKRNRTPVWFFVKIAPIRNEQDKVVLFLCTFSDITAFKQPIEDDSCKGWGKFARLTRALTSSRGVLQQLAPSVQKGENVHKHSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCVFKTTWDWIILILTFYTAILVPYNVSFKTRQNNVAWLVVDSIVDVIFLVDIVLNFHTTFVGPAGEVISDPKLIRMNYLKTWFVIDLLSCLPYDVINAFENVDEVSAFMGDPGKIGFADEIPPPLEGRESQGISSLFSSLKVVRLLRLGRVARKLDHYIEYGAAVLVLLVCVFGLAAHWMACIWYSIGDYEIFDEDTKTIRNNSWLYQLAMDIGTPYQFNGSGSGKWEGGPSKNSVYISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTTIFQQMYANTNRYHEMLNSVRDFLKLYQVPKGLSERVMDYIVSTWSMSRGIDTEKVLQICPKDMRADICVHLNRKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQDDEVVAILGKGDVFGDVFWKEATLAQSCANVRALTYCDLHVIKRDALQKVLEFYTAFSHSFSRNLILTYNLRKRIVFRKISDVKREEEERMKRKNEAPLILPPDHPVRRLFQRFRQQKEARLAAERGGRDLDDLDVEKGNALTDHTSANHSLVKASVVTVRESPATPVSFQAASTSTVSDHARLHAPGSECLGPKAGGGDCAKRKGWARFRDACGKGEDWNKVSKAESMETLPERTKASGEATLKKTDSCDSGITKSDLRLDNVGEARSPQDRSPILAEVKHSFYPIPEQTLQATVLEVKHELKEDIKALNAKMTAIEKQLSEILRILMSRGPAQSPQEMCEISRPQSPESDRDIFGAS", "length": 989, "header": "tr|A0A9J7K9V2-1|A0A9J7K9V2_CRIGR Isoform 1 of Potassium voltage-gated channel subfamily H member 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Kcnh1 PE=4 SV=1 CANONICAL=A0A9J7K9V2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H283-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V2/entry#A0A9J7H283-1", "sequence": { "sequence": 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"tr|A0A9J7H283-1|A0A9J7H283_CRIGR Computationally mapped isoform of Potassium voltage-gated channel subfamily H member 1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Kcnh1 PE=4 SV=1 CANONICAL=A0A9J7K9V2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K9V2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V2/entry#A0A9J7K9V2-1", "sequence": { "sequence": "MTMAGGRRGLVAPQNTFLENIVRRSNDTNFVLGNAQIVDWPIVYSNDGFCKLSGYHRAEVMQKSSACSFMYGELTDKDTIEKVRQTFENYEMNSFEILMYKRNRTPVWFFVKIAPIRNEQDKVVLFLCTFSDITAFKQPIEDDSCKGWGKFARLTRALTSSRGVLQQLAPSVQKGENVHKHSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCVFKTTWDWIILILTFYTAILVPYNVSFKTRQNNVAWLVVDSIVDVIFLVDIVLNFHTTFVGPAGEVISDPKLIRMNYLKTWFVIDLLSCLPYDVINAFENVDEVSAFMGDPGKIGFADEIPPPLEGRESQGISSLFSSLKVVRLLRLGRVARKLDHYIEYGAAVLVLLVCVFGLAAHWMACIWYSIGDYEIFDEDTKTIRNNSWLYQLAMDIGTPYQFNGSGSGKWEGGPSKNSVYISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTTIFQQMYANTNRYHEMLNSVRDFLKLYQVPKGLSERVMDYIVSTWSMSRGIDTEKVLQICPKDMRADICVHLNRKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQDDEVVAILGKGDVFGDVFWKEATLAQSCANVRALTYCDLHVIKRDALQKVLEFYTAFSHSFSRNLILTYNLRKRIVFRKISDVKREEEERMKRKNEAPLILPPDHPVRRLFQRFRQQKEARLAAERGGRDLDDLDVEKGNALTDHTSANHSLVKASVVTVRESPATPVSFQAASTSTVSDHARLHAPGSECLGPKAGGGDCAKRKGWARFRDACGKGEDWNKVSKAESMETLPERTKASGEATLKKTDSCDSGITKSDLRLDNVGEARSPQDRSPILAEVKHSFYPIPEQTLQATVLEVKHELKEDIKALNAKMTAIEKQLSEILRILMSRGPAQSPQEMCEISRPQSPESDRDIFGAS", "length": 989, "header": "tr|A0A9J7K9V2-1|A0A9J7K9V2_CRIGR Isoform 1 of Potassium voltage-gated channel subfamily H member 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Kcnh1 PE=4 SV=1 CANONICAL=A0A9J7K9V2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9V2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9V2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764830", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764830", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "delayed rectifier potassium channel activity", "id": "GO:0005251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005251", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9V2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V2" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9V2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of membrane potential", "id": "GO:0042391", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042391", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9V2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "voltage-gated potassium channel complex", "id": "GO:0008076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008076", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9V2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" }, { "start_pos": 26, "end_pos": 28, 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"XP_035303475", "name": "LOW QUALITY PROTEIN: annexin A7-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303475" }, "gene_names": [ { "name": "LOC113836595", "type": "recommended", "evidence": [ { "id": "A0A9J7K9V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V3" } ] }, { "name": "LOC113836595", "type": "synonym", "evidence": [ { "id": "XP_035303475", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303475" } ] } ], "protein_names": [ { "name": "Annexin", "type": "recommended", "evidence": [ { "id": "A0A9J7K9V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V3/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: annexin A7-like", "type": "synonym", "evidence": [ { "id": "XP_035303475", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303475" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035303475", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303475" } ] }, { "annotation": "Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9V3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V3#function" }, { "database": "UniProtKB", "id": "ARBA00037210", "url": "https://www.uniprot.org/uniprotkb/ARBA00037210#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9V3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113836595", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V3", "locus": {} } ], "crossref": [ { "id": "113836595", "url": "https://www.ncbi.nlm.nih.gov/gene/113836595", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001464", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001464", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037104", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037104", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113836595", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113836595", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7K9V3", "url": "https://www.orthodb.org/?gene=A0A9J7K9V3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10502", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10502", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10502:SF239", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10502:SF239", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00191", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00191", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035303475", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303475", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7K9V3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9V3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGGAYPPAPSVGYPGAGGYATPGGYPAPGGYPVSPSPGGVPVYPGGQGFGAPPGGASFSGYPQPPASLXGGPAQVPVPGGFPGGQMPSQYPGGHAPYPSQPAAMTQGTQGTIRAASNFDAMRDAEILRKAMKGFGTDEQAIVDVVSSRSNDQRQQIKTAFKTMYGKDLIKDLKSELSGNMEELILALFMPSTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIRDIVRCYQSEFGRDLEKDIKSDTSGHFERLLVSMCQGNRDENQSVNHQMAQDDAQHLYQAGEGKLGTDESCFNMILATRSFPQLKATMEAYSRMANRDLLSSVSREFSGYIESGLKTILQCALNRPAFFAERLYYSMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFTQMYQKTLSTMIASDTSGDYRKLLLAIVGQ", "length": 422, "header": "tr|A0A9J7K9V3-1|A0A9J7K9V3_CRIGR Isoform 1 of Annexin OS=Cricetulus griseus OX=10029 GN=LOC113836595 PE=3 SV=1 CANONICAL=A0A9J7K9V3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7K9V3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V3/entry#A0A9J7K9V3-1", "sequence": { "sequence": "MGGGAYPPAPSVGYPGAGGYATPGGYPAPGGYPVSPSPGGVPVYPGGQGFGAPPGGASFSGYPQPPASLXGGPAQVPVPGGFPGGQMPSQYPGGHAPYPSQPAAMTQGTQGTIRAASNFDAMRDAEILRKAMKGFGTDEQAIVDVVSSRSNDQRQQIKTAFKTMYGKDLIKDLKSELSGNMEELILALFMPSTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIRDIVRCYQSEFGRDLEKDIKSDTSGHFERLLVSMCQGNRDENQSVNHQMAQDDAQHLYQAGEGKLGTDESCFNMILATRSFPQLKATMEAYSRMANRDLLSSVSREFSGYIESGLKTILQCALNRPAFFAERLYYSMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFTQMYQKTLSTMIASDTSGDYRKLLLAIVGQ", "length": 422, "header": "tr|A0A9J7K9V3-1|A0A9J7K9V3_CRIGR Isoform 1 of Annexin OS=Cricetulus griseus OX=10029 GN=LOC113836595 PE=3 SV=1 CANONICAL=A0A9J7K9V3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 22, "start_aa": "Thr", "end_pos": 22, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr22", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9V3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9V3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:113836595", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113836595", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9V3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9V3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9V3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V3" } ], "pmid": "" }, { "name": "vesicle membrane", "id": "GO:0012506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012506", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9V3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9V3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V3" } ], "pmid": "" }, { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9V3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V3" } ], "pmid": "" }, { "name": "phosphatidylserine binding", "id": "GO:0001786", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001786", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9V3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 22 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 268, "end_pos": 270 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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"name": "Cdhr3", "type": "recommended", "evidence": [ { "id": "A0A9J7K9V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V6" } ] }, { "name": "Cdhr3", "type": "synonym", "evidence": [ { "id": "XP_035293111", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293111" } ] } ], "protein_names": [ { "name": "Cadherin-related family member 3", "type": "recommended", "evidence": [ { "id": "A0A9J7K9V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V6/entry#names_and_taxonomy" } ] }, { "name": "Cadherin-like protein 28", "type": "synonym", "evidence": [ { "id": "A0A9J7K9V6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V6/entry#names_and_taxonomy" } ] }, { "name": "cadherin-related family member 3", "type": "synonym", "evidence": [ { "id": "XP_035293111", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293111" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615813.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035293111", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293111" } ] }, { "annotation": "Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9V6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V6#function" }, { "database": "UniProtKB", "id": "ARBA00037319", "url": "https://www.uniprot.org/uniprotkb/ARBA00037319#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9V6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cdhr3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9V6", "locus": {} } ], "crossref": [ { "id": "A0A9J7K9V6", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7K9V6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100760935", "url": "https://www.ncbi.nlm.nih.gov/gene/100760935", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760935", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760935", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7K9V6", "url": 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This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035301701", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301701" } ] }, { "annotation": "Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. 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"XP_035301716", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301716" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 23% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035301731", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301731" } ] }, { "annotation": "May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. 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"A0A9J7K9Z2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9Z2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cadherin binding involved in cell-cell adhesion", "id": "GO:0098641", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098641", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9Z2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9Z2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 250, "end_pos": 252, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7K9Z2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9Z2" }, { "id": "PS51162", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51162" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Thyroglobulin type-1", "eco_id": "ECO_0000259", "start_pos": 114, "end_pos": 187, "start_aa": "Ala", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 }, { "start_pos": 163, "end_pos": 165 }, { "start_pos": 250, "end_pos": 252 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 32% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035301746", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301746" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K9Z8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9Z8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC118238936", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9Z8", "locus": {} } ], "crossref": [ { "id": "A0A9J7K9Z8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7K9Z8", "database": "AlphaFoldDB", "categories": [] }, { "id": "118238936", "url": "https://www.ncbi.nlm.nih.gov/gene/118238936", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028745", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028745", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:118238936", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:118238936", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7K9Z8", "url": "https://www.orthodb.org/?gene=A0A9J7K9Z8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44981", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44981", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44981:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44981:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_035301746", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301746", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7K9Z8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9Z8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K9Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9Z8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATAAVVAAAAERDMQAMRVPGKLKDPEDSKHWECDKGSTDILIICHDQLNVFGQDGHHIDDTRKRISLASSHSEEAAHCSPTHVEMTENDLAGKQHEIEELTQQLEGMRAIYGTEVLQRVSYEFEAAIKKRDSIITRLAANMQQSRKKTDQILEEFFQLTERSEKVQIQEQHVLSVFNFQARETLQRSPHSSAAAELVLLKQQVHDQQQLLEQQYRLLKDSQKKEEEFKNEVTFLQERLKVYEMVKLDVSWLVTAL", "length": 257, "header": "tr|A0A9J7K9Z8-1|A0A9J7K9Z8_CRIGR Isoform 1 of A-kinase anchor protein 9-like OS=Cricetulus griseus OX=10029 GN=LOC118238936 PE=4 SV=1 CANONICAL=A0A9J7K9Z8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7K9Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K9Z8/entry#A0A9J7K9Z8-1", "sequence": { "sequence": "MATAAVVAAAAERDMQAMRVPGKLKDPEDSKHWECDKGSTDILIICHDQLNVFGQDGHHIDDTRKRISLASSHSEEAAHCSPTHVEMTENDLAGKQHEIEELTQQLEGMRAIYGTEVLQRVSYEFEAAIKKRDSIITRLAANMQQSRKKTDQILEEFFQLTERSEKVQIQEQHVLSVFNFQARETLQRSPHSSAAAELVLLKQQVHDQQQLLEQQYRLLKDSQKKEEEFKNEVTFLQERLKVYEMVKLDVSWLVTAL", "length": 257, "header": "tr|A0A9J7K9Z8-1|A0A9J7K9Z8_CRIGR Isoform 1 of A-kinase anchor protein 9-like OS=Cricetulus griseus OX=10029 GN=LOC118238936 PE=4 SV=1 CANONICAL=A0A9J7K9Z8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7KAC9-1", "uniprot_ac": "A0A9J7KAC9", "uniprot_id": "A0A9J7KAC9_CRIGR", "mass": { "chemical_mass": 72009.0, "monoisotopic_mass": 72009.0 }, "refseq": { "ac": "XP_035304060", "name": "proton channel OTOP3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304060" }, "gene_names": [ { "name": "Otop3", "type": "recommended", "evidence": [ { "id": "A0A9J7KAC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAC9" } ] }, { "name": "Otop3", "type": "synonym", "evidence": [ { "id": "XP_035304060", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304060" } ] } ], "protein_names": [ { "name": "Proton channel OTOP3", "type": "synonym", "evidence": [ { "id": "A0A9J7KAC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAC9/entry#names_and_taxonomy" } ] }, { "name": "proton channel OTOP3", "type": "synonym", "evidence": [ { "id": 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This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304060", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304060" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAC9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAC9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Otop3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAC9", "locus": {} } ], "crossref": [ { "id": "A0A9J7KAC9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7KAC9", "database": "AlphaFoldDB", "categories": [] }, { "id": "100758515", "url": "https://www.ncbi.nlm.nih.gov/gene/100758515", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758515", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758515", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KAC9", "url": "https://www.orthodb.org/?gene=A0A9J7KAC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21522", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21522", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21522:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21522:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03189", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03189", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304060", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304060", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "34979", "url": "https://www.rhea-db.org/rhea/34979", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KAC9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAC9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGCRSSPKGHWGSGAGSTQKQQKHAGEERCPKWPRGTALQLLGGPRVGPSSVDSGWPEKKLLLGLSTLSSSPAPAKVAPMSSSETETTEAASTYDQADMAAKPIGLPCPPKQKSWLARHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNNVAVTLGDVWILLAALKALSLLWLLYYAVGTTRKPHAVLYRDPHAGPIWVRGSLVLFGSCTICLNVFRMGYDVSHIHCKSEVELIFPVVEIVFMSVQTWVLWRHCKDCVQVQTNFTRCGLMLTLATNLLLWVLAVTNDSMHREIEAELDALMEKFSGNETNTCMCLNATVCEVFRKGYLMLYPFSTEYCLICCAVLFVMWKNVGRHLTAHSGAHPNRPPFRLHGAIFGPLLGLLALVAGVCVFVLFQIEASGPNIGRQYFTLYYAFYVVVLPTMSLACLAGTAMHGLEERELDTLKNPTRSLDVVLLMCAALGQMGIAYFSIVAIVATQPHELLNQLILAYSLLLILQHITQNLFIIEGLHRRPLWEPVLSDVTDVTGKPDAELPRRGSLRELGQDLRRASRAYIHSYSHLNWKRRMLKEISLFLILCNITLWMMPAFGIHPEFENGLEKEFYGYRTWFTIVNFGLPVGVFYRMHSVGGLVEVYLGA", "length": 647, "header": "tr|A0A9J7KAC9-1|A0A9J7KAC9_CRIGR Isoform 1 of Proton channel OTOP3 OS=Cricetulus griseus OX=10029 GN=Otop3 PE=3 SV=1 CANONICAL=A0A9J7KAC9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KAC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAC9/entry#A0A9J7KAC9-1", "sequence": { "sequence": "MPGCRSSPKGHWGSGAGSTQKQQKHAGEERCPKWPRGTALQLLGGPRVGPSSVDSGWPEKKLLLGLSTLSSSPAPAKVAPMSSSETETTEAASTYDQADMAAKPIGLPCPPKQKSWLARHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNNVAVTLGDVWILLAALKALSLLWLLYYAVGTTRKPHAVLYRDPHAGPIWVRGSLVLFGSCTICLNVFRMGYDVSHIHCKSEVELIFPVVEIVFMSVQTWVLWRHCKDCVQVQTNFTRCGLMLTLATNLLLWVLAVTNDSMHREIEAELDALMEKFSGNETNTCMCLNATVCEVFRKGYLMLYPFSTEYCLICCAVLFVMWKNVGRHLTAHSGAHPNRPPFRLHGAIFGPLLGLLALVAGVCVFVLFQIEASGPNIGRQYFTLYYAFYVVVLPTMSLACLAGTAMHGLEERELDTLKNPTRSLDVVLLMCAALGQMGIAYFSIVAIVATQPHELLNQLILAYSLLLILQHITQNLFIIEGLHRRPLWEPVLSDVTDVTGKPDAELPRRGSLRELGQDLRRASRAYIHSYSHLNWKRRMLKEISLFLILCNITLWMMPAFGIHPEFENGLEKEFYGYRTWFTIVNFGLPVGVFYRMHSVGGLVEVYLGA", "length": 647, "header": "tr|A0A9J7KAC9-1|A0A9J7KAC9_CRIGR Isoform 1 of Proton channel OTOP3 OS=Cricetulus griseus OX=10029 GN=Otop3 PE=3 SV=1 CANONICAL=A0A9J7KAC9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. 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}, { "start_pos": 265, "end_pos": 267 }, { "start_pos": 298, "end_pos": 300 }, { "start_pos": 339, "end_pos": 341 }, { "start_pos": 499, "end_pos": 501 }, { "start_pos": 692, "end_pos": 694 }, { "start_pos": 721, "end_pos": 723 }, { "start_pos": 725, "end_pos": 727 }, { "start_pos": 736, "end_pos": 738 }, { "start_pos": 881, "end_pos": 883 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7KAS4-1", "uniprot_ac": "A0A9J7KAS4", "uniprot_id": "A0A9J7KAS4_CRIGR", "mass": { "chemical_mass": 124211.0, "monoisotopic_mass": 124211.0 }, "refseq": { "ac": "XP_035292715", "name": "myelin transcription factor 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035292715" }, "gene_names": [ { "name": "Myt1", "type": "recommended", "evidence": [ { "id": "A0A9J7KAS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAS4" } ] }, { "name": "Myt1", "type": "synonym", "evidence": [ { "id": "XP_035292715", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035292715" } ] } ], "protein_names": [ { "name": "Myelin transcription factor 1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7KAS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAS4/entry#names_and_taxonomy" } ] }, { "name": "myelin transcription factor 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035292715", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035292715" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615430.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035292715", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035292715" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAS4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAS4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Myt1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAS4", "locus": {} } ], "crossref": [ { "id": "A0A9J7KAS4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7KAS4", "database": "AlphaFoldDB", "categories": [] }, { "id": "100765954", "url": "https://www.ncbi.nlm.nih.gov/gene/100765954", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002515", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002515", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013681", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013681", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765954", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765954", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KAS4", "url": "https://www.orthodb.org/?gene=A0A9J7KAS4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10816", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10816", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10816:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10816:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01530", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01530", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08474", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08474", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035292715", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035292715", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H3D4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3D4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H3D4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3D4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H3Z4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3Z4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H3Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3Z4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAS4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAS4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLESDDKRARTRSKTLRGPPETTGADLSCPTPGCTGSGHVRGKYSRHRSLQSCPLAKKRKLEDAEAEHLVSKRKSHPLRLALDEGYRMDSDGSEDAEVKDASVSDESEGPLEETEAEMSGQEEIHHPQPAEGKSLIKSHFGSNPTSSPSGFSKGSYSSYQGIIATSLLNLGQIAEETLVQEDSVPVAKLGPTVVHQLQDEAAIAAPNDEDEKDLFIHPEDVEEVIEVTSERSQEPCPQSLEDMISEESSKQKGVLGHEEEGEDDDEEEEEEEEEEEEGEEEEEEEEEEEEEEEEVEEEEEEEEEEEEEEETTPNVIFGEDTSHTSAQKVSPEFRSPELSSPKPEYSVIVEVRSDDDKDEDSHSQKSAVTDESEMYDMMTRGNLGLLEQAIALKAEQVRAVCEPGCLPAEQGHLGPGEPGKVAKPLDVVRKSCYSKDPSRVEKREIKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRIPPEILAMHENVLKCPTPGCTGQGHVNSNRNTHRSLSGCPIAAAEKLAKSHEKQQLQTGDPPKNNSNSDRILRPMCFVKQLEVPPYGSYRPNVAPATPRANLAKELEKFSKVTFDYASFDAQVFGKRMLAPKIQTSETSPKAFQCFDYSHDAEAAHMAATAILNLSTRCWEMPENLSTKPQDLPSKAVDIEVDENGTLDLSMHKHRKRENTFPSSSSCSSSPGVKSPDVSQRQNTTSAPSSSMTSPQSSQASRQDEWDRPLDYTKPSRLREEETEESEPAAHSFASSEADDQEVSEENFEERKYPGEVTLTNFKLKFLSKDIKKELLTCPTPGCDGSGHITGNYASHRSLSGCPLADKSLRNLMAAHSADLKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGLKVAPTKDDKEDPELMKCPVPGCVGLGHISGKYASHRSASGCPLAARRQKEGALNGSSFSWKSLKNEGPTCPTPGCDGSGHANGSFLTHRSLSGCPRATFAGKKGKLSGDEILSPKFKTSDVLENDEEIKQLNQEIRDLNESNSEMEAAMVQLQSQISSMEKNLKNIEEENKLIEEQNEALFLELSGLSQALIQSLANIRLPHMEPICEQNFDAYVNTLTDMYSNQDCYQNPENKGLLETIKQAVRGIQV", "length": 1131, "header": "tr|A0A9J7KAS4-1|A0A9J7KAS4_CRIGR Isoform 1 of Myelin transcription factor 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Myt1 PE=3 SV=1 CANONICAL=A0A9J7KAS4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H3D4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAS4/entry#A0A9J7H3D4-1", "sequence": { "sequence": 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"length": 1088, "header": "tr|A0A9J7H3D4-1|A0A9J7H3D4_CRIGR Computationally mapped isoform of Myelin transcription factor 1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Myt1 PE=3 SV=1 CANONICAL=A0A9J7KAS4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H3Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAS4/entry#A0A9J7H3Z4-1", "sequence": { "sequence": "MSLESDDKRARTRSKTLRGPPETTGADLSCPTPGCTGSGHVRGKYSRHRSLQSCPLAKKRKLEDAEAEHLVSKRKSHPLRLALDEGYRMDSDGSEDAEVKDASVSDESEGPLEETEAEMSGQEEIHHPQPAEGKSLIKSHFGSNPTSSPSGFSKGSYSSYQGIIATSLLNLGQIAEETLVQEDSVPVAKLGPTVVHQLQDEAAIAAPNDEDEKDLFIHPEDVEEVIEVTSERSQEPCPQSLEDMISEESSKQKGVLGHEEEGEDDDEEEEEEEEEEEEGEEEEEEEEEEEVEEEEEEEEEEEEEEETTPNVIFGEDTSHTSAQKVSPEFRSPELSSPKPEYSVIVEVRSDDDKDEDSHSQKSAVTDESEMYDMMTRGNLGLLEQAIALKAEQVRAVCEPGCLPAEQGHLGPGEPGKVAKPLDVVRKSCYSKDPSRVEKREIKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRIPPEILAMHENVLKCPTPGCTGQGHVNSNRNTHRSLSGCPIAAAEKLAKSHEKQQLQTGDPPKNNSNSDRILRPMCFVKQLEVPPYGSYRPNVAPATPRANLAKELEKFSKVTFDYASFDAQVFGKRMLAPKIQTSETSPKAFQCFDYSHDAEAAHMAATAILNLSTRCWEMPENLSTKPQDLPSKAVDIEVDENGTLDLSMHKHRKRENTFPSSSSCSSSPGVKSPDVSQRQNTTSAPSSSMTSPQSSQASRQDEWDRPLDYTKPSRLREEETEESEPAAHSFASSEADDQEVSEENFEERKYPGEVTLTNFKLKFLSKDIKKELLTCPTPGCDGSGHITGNYASHRSLSGCPLADKSLRNLMAAHSADLKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGLKVAPTKDDKEDPELMKCPVPGCVGLGHISGKYASHRSASGCPLAARRQKEGALNGSSFSWKSLKNEGPTCPTPGCDGSGHANGSFLTHRSLSGCPRATFAGKKGKLSGDEILSPKFKTSDVLENDEEIKQLNQEIRDLNESNSEMEAAMVQLQSQISSMEKNLKNIEEENKLIEEQNEALFLELSGLSQALIQSLANIRLPHMEPICEQNFDAYVNTLTDMYSNQDCYQNPENKGLLETIKQAVRGIQV", "length": 1126, "header": "tr|A0A9J7H3Z4-1|A0A9J7H3Z4_CRIGR Computationally mapped isoform of Myelin transcription factor 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Myt1 PE=3 SV=1 CANONICAL=A0A9J7KAS4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KAS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAS4/entry#A0A9J7KAS4-1", "sequence": { "sequence": "MSLESDDKRARTRSKTLRGPPETTGADLSCPTPGCTGSGHVRGKYSRHRSLQSCPLAKKRKLEDAEAEHLVSKRKSHPLRLALDEGYRMDSDGSEDAEVKDASVSDESEGPLEETEAEMSGQEEIHHPQPAEGKSLIKSHFGSNPTSSPSGFSKGSYSSYQGIIATSLLNLGQIAEETLVQEDSVPVAKLGPTVVHQLQDEAAIAAPNDEDEKDLFIHPEDVEEVIEVTSERSQEPCPQSLEDMISEESSKQKGVLGHEEEGEDDDEEEEEEEEEEEEGEEEEEEEEEEEEEEEEVEEEEEEEEEEEEEEETTPNVIFGEDTSHTSAQKVSPEFRSPELSSPKPEYSVIVEVRSDDDKDEDSHSQKSAVTDESEMYDMMTRGNLGLLEQAIALKAEQVRAVCEPGCLPAEQGHLGPGEPGKVAKPLDVVRKSCYSKDPSRVEKREIKCPTPGCDGTGHVTGLYPHHRSLSGCPHKDRIPPEILAMHENVLKCPTPGCTGQGHVNSNRNTHRSLSGCPIAAAEKLAKSHEKQQLQTGDPPKNNSNSDRILRPMCFVKQLEVPPYGSYRPNVAPATPRANLAKELEKFSKVTFDYASFDAQVFGKRMLAPKIQTSETSPKAFQCFDYSHDAEAAHMAATAILNLSTRCWEMPENLSTKPQDLPSKAVDIEVDENGTLDLSMHKHRKRENTFPSSSSCSSSPGVKSPDVSQRQNTTSAPSSSMTSPQSSQASRQDEWDRPLDYTKPSRLREEETEESEPAAHSFASSEADDQEVSEENFEERKYPGEVTLTNFKLKFLSKDIKKELLTCPTPGCDGSGHITGNYASHRSLSGCPLADKSLRNLMAAHSADLKCPTPGCDGSGHITGNYASHRSLSGCPRAKKSGLKVAPTKDDKEDPELMKCPVPGCVGLGHISGKYASHRSASGCPLAARRQKEGALNGSSFSWKSLKNEGPTCPTPGCDGSGHANGSFLTHRSLSGCPRATFAGKKGKLSGDEILSPKFKTSDVLENDEEIKQLNQEIRDLNESNSEMEAAMVQLQSQISSMEKNLKNIEEENKLIEEQNEALFLELSGLSQALIQSLANIRLPHMEPICEQNFDAYVNTLTDMYSNQDCYQNPENKGLLETIKQAVRGIQV", 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This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035302928", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302928" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAW2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAW2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tmc2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAW2", "locus": {} } ], "crossref": [ { "id": "A0A9J7KAW2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7KAW2", "database": "AlphaFoldDB", "categories": [] }, { "id": "100751244", "url": "https://www.ncbi.nlm.nih.gov/gene/100751244", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038900", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038900", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751244", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751244", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KAW2", "url": "https://www.orthodb.org/?gene=A0A9J7KAW2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23302", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23302", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23302:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23302:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07810", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07810", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035302928", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302928", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KAW2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAW2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTLCIAMSTSVASSVSTGESLSEEEMAQILEQVEEKKKLIATMRNKPWPMAKKLRELREAQAFVEKYEGALGKGKGKHLYAYRMLMTKLRVLSVSFQKWIKFKRDFDNFKTQCIPWEMKIKDIESHFGSSVASYFIFLRWMYGVNLVLFALIFGLVIIPEVLMGMPYGSIPRKTVPRAEEEKAMDFAVLWDFEGYIKYSALFYGYYNNQRTIGWLRYRLPMAYFMVGVSVFGYSLMIVIRSMASNTQGSTGEGESDNFTFSFKMFTSWDYLIGNSETADNKYVSITTSFKESIVDEQESNKEENIHLTRFLRVLANFLILCCLCGSGYLIYFVVKRSQEFSKMQNVSWYERNEVEIVMSLLGMFCPPLFETIAALENYHPRTGLKWQLGRIFALFLGNLYTFLLALMDDVHLKLSNEEKIKNITHWTLFNYYNSSGGNESVPRPPPHPADVPRGSCWETAVGIEFMRLTVSDMLVTYLTILVGDFLRACFVRFMNHCWCWDLEAGFPSYAEFDISGNVLGLIFNQGMIWMGSFYAPGLVGINVLRLLTSMYFQCWAVMSSNVPHERVFKASRSNNFYMGLLLLVLFLSLLPVAYTVMSLPPSFDCGPFSGKNRMYDVLHETIENDFPKFLGKIFAFLANPGLIIPAILLMFLAIYYLNSVSKSLSRANAQLRKKIQALREVEKNHKSIKGRAIITNSEDTLKNSSKNATQLQLTKEEPTSYSPSQIQTMDKKVKGPGSSSTNGRASQPTSRHLVGSQPPRVRPDSGQPQSQTYICRSASGKSTKRPHN", "length": 788, "header": "tr|A0A9J7KAW2-1|A0A9J7KAW2_CRIGR Isoform 1 of Transmembrane channel-like protein OS=Cricetulus griseus OX=10029 GN=Tmc2 PE=3 SV=1 CANONICAL=A0A9J7KAW2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KAW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAW2/entry#A0A9J7KAW2-1", "sequence": { "sequence": "MTLCIAMSTSVASSVSTGESLSEEEMAQILEQVEEKKKLIATMRNKPWPMAKKLRELREAQAFVEKYEGALGKGKGKHLYAYRMLMTKLRVLSVSFQKWIKFKRDFDNFKTQCIPWEMKIKDIESHFGSSVASYFIFLRWMYGVNLVLFALIFGLVIIPEVLMGMPYGSIPRKTVPRAEEEKAMDFAVLWDFEGYIKYSALFYGYYNNQRTIGWLRYRLPMAYFMVGVSVFGYSLMIVIRSMASNTQGSTGEGESDNFTFSFKMFTSWDYLIGNSETADNKYVSITTSFKESIVDEQESNKEENIHLTRFLRVLANFLILCCLCGSGYLIYFVVKRSQEFSKMQNVSWYERNEVEIVMSLLGMFCPPLFETIAALENYHPRTGLKWQLGRIFALFLGNLYTFLLALMDDVHLKLSNEEKIKNITHWTLFNYYNSSGGNESVPRPPPHPADVPRGSCWETAVGIEFMRLTVSDMLVTYLTILVGDFLRACFVRFMNHCWCWDLEAGFPSYAEFDISGNVLGLIFNQGMIWMGSFYAPGLVGINVLRLLTSMYFQCWAVMSSNVPHERVFKASRSNNFYMGLLLLVLFLSLLPVAYTVMSLPPSFDCGPFSGKNRMYDVLHETIENDFPKFLGKIFAFLANPGLIIPAILLMFLAIYYLNSVSKSLSRANAQLRKKIQALREVEKNHKSIKGRAIITNSEDTLKNSSKNATQLQLTKEEPTSYSPSQIQTMDKKVKGPGSSSTNGRASQPTSRHLVGSQPPRVRPDSGQPQSQTYICRSASGKSTKRPHN", "length": 788, "header": "tr|A0A9J7KAW2-1|A0A9J7KAW2_CRIGR Isoform 1 of Transmembrane channel-like protein OS=Cricetulus griseus OX=10029 GN=Tmc2 PE=3 SV=1 CANONICAL=A0A9J7KAW2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAW2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAW2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAW2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAW2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751244", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751244", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "vestibular reflex", "id": "GO:0060005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060005", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAW2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAW2" } ], "pmid": "" }, { "name": "detection of mechanical stimulus involved in sensory perception of sound", "id": "GO:0050910", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050910", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAW2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAW2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAW2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAW2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "mechanosensitive monoatomic ion channel activity", "id": "GO:0008381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008381", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAW2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAW2" } ], "pmid": "" }, { "name": "voltage-gated calcium channel activity", "id": "GO:0005245", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005245", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAW2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAW2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 422, "end_pos": 424, "annotation": "n_glycosylation_sequon" }, { "start_pos": 433, "end_pos": 435, "annotation": "n_glycosylation_sequon" }, { "start_pos": 438, "end_pos": 440, "annotation": "n_glycosylation_sequon" }, { "start_pos": 703, "end_pos": 705, "annotation": "n_glycosylation_sequon" }, { "start_pos": 707, "end_pos": 709, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7KAW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAW2" }, { "id": "PF07810", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07810" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TMC", "eco_id": "ECO_0000259", "start_pos": 456, "end_pos": 571, "start_aa": "Cys", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 257, "end_pos": 259 }, { "start_pos": 345, "end_pos": 347 }, { "start_pos": 422, "end_pos": 424 }, { "start_pos": 433, "end_pos": 435 }, { "start_pos": 438, "end_pos": 440 }, { "start_pos": 703, "end_pos": 705 }, { "start_pos": 707, "end_pos": 709 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"A0A9J7KAW8", "uniprot_id": "A0A9J7KAW8_CRIGR", "mass": { "chemical_mass": 107891.0, "monoisotopic_mass": 107891.0 }, "refseq": { "ac": "XP_035302781", "name": "zinc fingers and homeoboxes protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302781" }, "gene_names": [ { "name": "Zhx3", "type": "recommended", "evidence": [ { "id": "A0A9J7KAW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAW8" } ] }, { "name": "Zhx3", "type": "synonym", "evidence": [ { "id": "XP_035302781", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302781" } ] } ], "protein_names": [ { "name": "Zinc fingers and homeoboxes protein 3", "type": "recommended", "evidence": [ { "id": "A0A9J7KAW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAW8/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger and homeodomain protein 3", "type": "synonym", "evidence": [ { "id": "A0A9J7KAW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAW8/entry#names_and_taxonomy" } ] }, { "name": "zinc fingers and homeoboxes protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035302781", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302781" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035302781", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302781" } ] }, { "annotation": "Acts as a transcriptional repressor. Involved in the early stages of mesenchymal stem cell (MSC) osteogenic differentiation. Is a regulator of podocyte gene expression during primary glomerula disease. Binds to promoter DNA.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAW8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAW8#function" }, { "database": "UniProtKB", "id": "ARBA00059166", "url": "https://www.uniprot.org/uniprotkb/ARBA00059166#function" }, { "database": "UniProtKB", "id": "A0A9J7H1C2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1C2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAW8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAW8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Zhx3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAW8", "locus": {} } ], "crossref": [ { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100770846", "url": "https://www.ncbi.nlm.nih.gov/gene/100770846", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041057", "url": 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"database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18387", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18387", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035302781", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302781", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H1C2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1C2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1C2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1C2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAW8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAW8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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987, "header": "tr|A0A9J7KAW8-1|A0A9J7KAW8_CRIGR Isoform 1 of Zinc fingers and homeoboxes protein 3 OS=Cricetulus griseus OX=10029 GN=Zhx3 PE=3 SV=1 CANONICAL=A0A9J7KAW8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H1C2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAW8/entry#A0A9J7H1C2-1", "sequence": { "sequence": "MASKRKSTTPCMIPVKTVVLQGASTEAQPVDTLPEGPQQDLPSEAPAASSEAVPNPSSTDGSALANGHRSTLDGYVYSCKDCDFRSQDMTQFVGHMNSEHTDFNKDPNFVCTGCNFLAKTPEGLSLHNAKCHSGEASFLWNVTTPDNHMVVEQNVPESPGTCDLAGESATEGIDGQAEIIITKTPIMKIMKGKAEAKKIHMLKENAPNQPVGEALPKPLTGEAEVKEGDHTFANGAAPVSQASASSSKPPHAANGPLIGTVPVLPAGIAQFLSLQQQPPVHAQHHTHQPLPTSKALPKVMIPLSSIPTYNAAMDSNSFLKNSFHKFPYPTKAELCYLTVVTKYPEEQLKIWFTAQRLKQGISWSPEEIEDARKKMFNTVIQSVPQPTITVLNTPLVASTGNVQHLIQAALPGHVVGQPEGTAGGLLVTQPLMTNGLQGSSSSLPLTTASVPKSTVAPINTVCSNTTSAVKVVNAAQSLLTACPSITSQAFLDANIYKNKKSHEQLSALKGSFCRNQFPGQSEVEHLTKVTGLSTREVRKWFSDRRYHCRNLKGSRTMMPGEHGSVLIDSVPEVPFPLSSKVPEVTCIPTTTSLASHPATKRQSWHQTPDFTPTKYKERAPEQLRVLESSFAQNPLPPEEELDRLRSETKMTRREIDGWFSERRKKVNAEDTKKAEGQVYQEEEEGAEVEGGDEELASELRVLGENGSPEMFLSHTLAERKVSPIKINLKNLRVTEASGKNELPGLGVCETEEDGLNKLVEQPPGKVSYKKTAQQRHLLRQLFVQTQWPSNQDYDSIMAQTGLPRPEVVRWFGDSRYALKNGQLKWYEDYKRGNFPPGLLVIAPGNRELLQDYYMTHKMLCEGDLQTLCDKTQMSAQQVKQWFAEKMGEETRAVADTSSEDKGPGTGEPVAVHRVLGDAYSEMSENSESWEPSAPEASSEPFDTLSPQSGRQLETD", "length": 955, "header": "tr|A0A9J7H1C2-1|A0A9J7H1C2_CRIGR Computationally mapped isoform of Zinc fingers and homeoboxes protein 3 OS=Cricetulus griseus OX=10029 GN=Zhx3 PE=3 SV=1 CANONICAL=A0A9J7KAW8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KAW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAW8/entry#A0A9J7KAW8-1", "sequence": { "sequence": "MASKRKSTTPCMIPVKTVVLQGASTEAQPVDTLPEGPQQDLPSEAPAASSEAVPNPSSTDGSALANGHRSTLDGYVYSCKDCDFRSQDMTQFVGHMNSEHTDFNKDPNFVCTGCNFLAKTPEGLSLHNAKCHSGEASFLWNVTTPDNHMVVEQNVPESPGTCDLAGESATEGIDGQAEIIITKTPIMKIMKGKAEAKKIHMLKENAPNQPVGEALPKPLTGEAEVKEGDHTFANGAAPVSQASASSSKPPHAANGPLIGTVPVLPAGIAQFLSLQQQPPVHAQHHTHQPLPTSKALPKVMIPLSSIPTYNAAMDSNSFLKNSFHKFPYPTKAELCYLTVVTKYPEEQLKIWFTAQRLKQGISWSPEEIEDARKKMFNTVIQSVPQPTITVLNTPLVASTGNVQHLIQAALPGHVVGQPEGTAGGLLVTQPLMTNGLQGSSSSLPLTTASVPKSTVAPINTVCSNTTSAVKVVNAAQSLLTACPSITSQAFLDANIYKNKKSHEQLSALKGSFCRNQFPGQSEVEHLTKVTGLSTREVRKWFSDRRYHCRNLKGSRTMMPGEHGSVLIDSVPEVPFPLSSKVPEVTCIPTTTSLASHPATKRQSWHQTPDFTPTKYKERAPEQLRVLESSFAQNPLPPEEELDRLRSETKMTRREIDGWFSERRKKVNAEDTKKAEGQVYQEEEEGAEVEGGDEELASELRVLGENGSPEMFLSHTLAERKVSPIKINLKNLRVTEASGKNELPGLGVCETEEDGLNKLVEQPPGKVSYKKTAQQRHLLRQLFVQTQWPSNQDYDSIMAQTGLPRPEVVRWFGDSRYALKNGQLKWYEDYKRGNFPPGLLVIAPGNRELLQDYYMTHKMLCEGDLQTLCDKTQMSAQQVKQWFAEKMGEETRAVADTSSEDKGPGTGEPVAVHRVLGDAYSEMSENSESWEPSAPEASSEPFDTLSPQSGRQLGKGLMGFMHDFPLNLREDTVTEWAQGAGTVASKAT", "length": 987, "header": "tr|A0A9J7KAW8-1|A0A9J7KAW8_CRIGR Isoform 1 of Zinc fingers and homeoboxes protein 3 OS=Cricetulus griseus OX=10029 GN=Zhx3 PE=3 SV=1 CANONICAL=A0A9J7KAW8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAW8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAW8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAW8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAW8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770846", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770846", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAW8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAW8" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAW8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAW8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAW8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAW8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAW8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAW8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAW8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAW8" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAW8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAW8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 464, "end_pos": 466, "annotation": "n_glycosylation_sequon" }, { "start_pos": 705, "end_pos": 707, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7KAW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAW8" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Homeobox", "eco_id": "ECO_0000259", "start_pos": 319, "end_pos": 362, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 141, "end_pos": 143 }, { "start_pos": 464, "end_pos": 466 }, { "start_pos": 705, "end_pos": 707 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { 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}, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7KCE9-1", "uniprot_ac": "A0A9J7KCE9", "uniprot_id": "A0A9J7KCE9_CRIGR", "mass": { "chemical_mass": 85071.0, "monoisotopic_mass": 85071.0 }, "refseq": { "ac": "XP_035304704", "name": "ATP-dependent RNA helicase DQX1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304704" }, "gene_names": [ { "name": "Dqx1", "type": "recommended", "evidence": [ { "id": "A0A9J7KCE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE9" } ] }, { "name": "Dqx1", "type": "synonym", "evidence": [ { "id": "XP_035304704", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304704" } ] } ], "protein_names": [ { "name": "ATP-dependent RNA helicase homolog DQX1", "type": "recommended", "evidence": [ { "id": "A0A9J7KCE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE9/entry#names_and_taxonomy" } ] }, { "name": "ATP-dependent RNA helicase DQX1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035304704", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304704" } ] }, { "name": "DEAQ box polypeptide 1", "type": "synonym", "evidence": [ { "id": "A0A9J7KCE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304704", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304704" } ] }, { "annotation": "Might be involved in RNA metabolism; it is missing helicase motif III and may not have helicase activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCE9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE9#function" }, { "database": "UniProtKB", "id": "ARBA00093385", "url": "https://www.uniprot.org/uniprotkb/ARBA00093385#function" }, { "database": "UniProtKB", "id": "A0A9J7KAY0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAY0#function" }, { "database": "UniProtKB", "id": "A0A8C2LS76", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS76#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCE9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dqx1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE9", "locus": {} } ], "crossref": [ { "id": "A0A9J7KCE9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7KCE9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18791", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18791", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100761206", "url": "https://www.ncbi.nlm.nih.gov/gene/100761206", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011709", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011709", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014001", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014001", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761206", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761206", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PPQWVLY", "url": "https://omabrowser.org/oma/group/PPQWVLY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LS76", "url": "https://www.orthodb.org/?gene=A0A8C2LS76", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7KCE9", "url": "https://www.orthodb.org/?gene=A0A9J7KCE9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18934", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18934", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18934:SF108", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18934:SF108", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04408", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04408", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07717", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07717", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304704", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304704", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LS76", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LS76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS76-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAY0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KCE9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KCE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLHVTPAAPVLVTRSLRPNYKQGKSPLVVAPQKHPALLPGKQVPLGRMDPKALSSVLWTATMASGRAEESEPSLGESELAVNPFDGLPFSSCYYELLEQRRALPIWAARFLFLEHLESSPTGVVLVSGEPGSGKSTQIPQWCAEFALARGFQTGQVTVTQPYPLAAMSLASRVADEMDLTLGHEIGYSIPQEDCTGPNTMLRFCWDRLLLQEVASTRGPGAWSVLIVDEAQERSVASDLLQGLLRDTKLRNLPGDPRVVVVTDPALEPKLQAFWANSPIVRVPREPGGNPTLVYRDTVPTDLVEAACQAVLELCRQEEAPGDVLVYLPSEEEISLCCESLSRELGMLAVPGPPPRVLPLHPGCGQAIQAVYEDTDMSVRKIVVTHWLADFSFSLPSIQHVIDSGLELRSVYSPRIRAESQVLRPISKCQAEARRLRARGFPPGSCLRLYSKSILELEAPPLPHPKVLEENLSSLVLLLKRKQIAEPGECHFLDRPAPEALMQALEDLDYLAALDDDGDLSDLGIILSEFPLLPELAKALLASCEFNCVDEMLTLSAMLTAAPGFTRPPLCAEEAALRRALEHADGDHSSLIQIYEAFVQSGADEVWCQARGLNWAALCQARKLRAELVELMQQIELPLSQPAFGSEQNRRDLQKALLSGFFLKVAQDIDGTGNYLLLTHKHVAQLSSCCSYRNRRAPAQPPAWVLYHSFSISKDNCLCIVSEIQPQMLVELAPPYFLSNLPPSESRDFLNQLREGPAAEAESSSPQEYGDGCVLQ", "length": 775, "header": "tr|A0A9J7KCE9-1|A0A9J7KCE9_CRIGR Isoform 1 of ATP-dependent RNA helicase homolog DQX1 OS=Cricetulus griseus OX=10029 GN=Dqx1 PE=4 SV=1 CANONICAL=A0A9J7KCE9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LS76-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE9/entry#A0A8C2LS76-1", "sequence": { "sequence": "MASGRAEESEPSLGESELAVNPFDGLPFSSCYYELLEQRRALPIWAARFLFLEHLESSPTGVVLVSGEPGSGKSTQIPQWCAEFALARGFQTGQVTVTQPYPLAAMSLASRVADEMDLTLGHEIGYSIPQEDCTGPNTMLRFCWDRLLLQEVASTRGPGAWSVLIVDEAQERSVASDLLQGLLRDTKLRNLPGDPRVVVVTDPALEPKLQAFWANSPIVRVPREPGGNPTLVYRDTVPTDLVEAACQAVLELCRQEEAPGDVLVYLPSEEEISLCCESLSRELGMLAVPGPPPRVLPLHPGCGQAIQAVYEDTDMSVRKIVVTHWLADFSFSLPSIQHVIDSGLELRSVYSPRIRAESQVLRPISKCQAEARRLRARGFPPGSCLRLYSKSILELEAPPLPHPKVLEENLSSLVLLLKRKQIAEPGECHFLDRPAPEALMQALEDLDYLAALDDDGDLSDLGIILSEFPLLPELAKALLASCEFNCVDEMLTLSAMLTAAPGFTRPPLCAEEAALRRALEHADGDHSSLIQIYEAFVQSGADEVWCQARGLNWAALCQARKLRAELVELMQQIELPLSQPAFGSEQNRRDLQKALLSGFFLKVAQDIDGTGNYLLLTHKHVAQLSSCCSYRNRRAPAQPPAWVLYHSFSISKDNCLCIVSEIQPQMLVELAPPYFLSNLPPSESRDFLNQLREGPAAEAESSSPQEYGDGCVLQ", "length": 714, "header": "tr|A0A8C2LS76-1|A0A8C2LS76_CRIGR Computationally mapped isoform of ATP-dependent RNA helicase homolog DQX1 OS=Cricetulus griseus OX=10029 GN=Dqx1 PE=4 SV=1 CANONICAL=A0A9J7KCE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KAY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE9/entry#A0A9J7KAY0-1", "sequence": { "sequence": "MLHVTPAAPVLVTRSLRPNYKQGKSPLVVAPQKHPALLPGKQVPLGRMDPKALSSVLWTATMASGRAEESEPSLGESELAVNPFDGLPFSSCYYELLEQRRALPIWAARFLFLEHLESSPTGVVLVSGEPGSGKSTQIPQWCAEFALARGFQTGQVTVTQPYPLAAMSLASRVADEMDLTLGHEIGYSIPQEDCTGPNTMLRFCWDRLLLQEVASTRGPGAWSVLIVDEAQERSVASDLLQGLLRDTKLRNLPGDPRVVVVTDPALEPKLQAFWANSPIVRVPREPGGNPTLVYRDTVPTDLVEAACQAVLELCRQEEAPGDVLVYLPSEEEISLCCESLSRELGMLAVPGPPPRVLPLHPGCGQAIQAVYEDTDMSVRKIVVTHWLADFSFSLPSIQHVIDSGLELRSVYSPRIRAESQVLRPISKCQAEARRLRARGFPPGSCLRLYSKSILELEAPPLPHPKVLEENLSSLVLLLKRKQIAEPGECHFLDRPAPEALMQALEDLDYLAALDDDGDLSDLGIILSEFPLLPELAKALLASCEFNCVDEMLTLSAMLTAAPGFTRPPLCAEEAALRRALEHADGDHSSLIQIYEAFVQSGADEVWCQARGLNWAALCQARKLRAELVELMQQIELPLSQPAFGSEQNRRDLQKALLSGFFLKT", "length": 664, "header": "tr|A0A9J7KAY0-1|A0A9J7KCE9_CRIGR Computationally mapped isoform of ATP-dependent RNA helicase homolog DQX1 OS=Cricetulus griseus OX=10029 GN=Dqx1 PE=4 SV=1 CANONICAL=A0A9J7KCE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KCE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE9/entry#A0A9J7KCE9-1", "sequence": { "sequence": "MLHVTPAAPVLVTRSLRPNYKQGKSPLVVAPQKHPALLPGKQVPLGRMDPKALSSVLWTATMASGRAEESEPSLGESELAVNPFDGLPFSSCYYELLEQRRALPIWAARFLFLEHLESSPTGVVLVSGEPGSGKSTQIPQWCAEFALARGFQTGQVTVTQPYPLAAMSLASRVADEMDLTLGHEIGYSIPQEDCTGPNTMLRFCWDRLLLQEVASTRGPGAWSVLIVDEAQERSVASDLLQGLLRDTKLRNLPGDPRVVVVTDPALEPKLQAFWANSPIVRVPREPGGNPTLVYRDTVPTDLVEAACQAVLELCRQEEAPGDVLVYLPSEEEISLCCESLSRELGMLAVPGPPPRVLPLHPGCGQAIQAVYEDTDMSVRKIVVTHWLADFSFSLPSIQHVIDSGLELRSVYSPRIRAESQVLRPISKCQAEARRLRARGFPPGSCLRLYSKSILELEAPPLPHPKVLEENLSSLVLLLKRKQIAEPGECHFLDRPAPEALMQALEDLDYLAALDDDGDLSDLGIILSEFPLLPELAKALLASCEFNCVDEMLTLSAMLTAAPGFTRPPLCAEEAALRRALEHADGDHSSLIQIYEAFVQSGADEVWCQARGLNWAALCQARKLRAELVELMQQIELPLSQPAFGSEQNRRDLQKALLSGFFLKVAQDIDGTGNYLLLTHKHVAQLSSCCSYRNRRAPAQPPAWVLYHSFSISKDNCLCIVSEIQPQMLVELAPPYFLSNLPPSESRDFLNQLREGPAAEAESSSPQEYGDGCVLQ", "length": 775, "header": "tr|A0A9J7KCE9-1|A0A9J7KCE9_CRIGR Isoform 1 of ATP-dependent RNA helicase homolog DQX1 OS=Cricetulus griseus OX=10029 GN=Dqx1 PE=4 SV=1 CANONICAL=A0A9J7KCE9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAY0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAY0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAY0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAY0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761206", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761206", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A474-1", "protein_name": "ATP-dependent RNA helicase homolog DQX1", "gene_name": "Dqx1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASGLAEESEPSPGESELAVNPFDGLPFSSCYYELLEQRRALPIWAARFLFLEHLESSPTGVVLVSGEPGSGKSTQIPQWCAEFALARGFQTGQVTVTQPYPLAAMSLASRVADEMDLTLGHEIGYSIPQEDCTGPNTMLRFCWDRLFLQEVASTRGPGAWSVLVLDEAQERSVASDLLQGLLRDTRLRNLPGDPRVVIVTDSALEPKFQAFWGNSPTVHVPREPGENPTLTYKDTVPADLVEAACQAVLELCQREEAPGDVLVYLPSEEKWALVFLSLSKREMGMLAVPGPLPRVLPLHPGCGQAIQTVYEDTDVSVRKIVVTHWLADFSFSLPFIQHVIDSGLELRSVYNPRIRAESQVLRRISKCQAEARLLRARGFPPGTCLRLYSKSTLDLEAPPLPHPKVCEENLSSLVLLLKRKQIAEPGECHFLDRPAPEALMQALEDLDYLAALDDDGDLSDLGIILSEFPLPPELAKALLASCEFNCVDEMLTLAAMLTAAPGFTRPPLCAGEAALRRGLEHADGDHSSLIQVYEAFVQSGADETWCQARGLSWEALCQARKLRAELLELMQRIELPLSLPAFGSEQNRRDLQKALLSGYFLKVARDTDGTGNYLLLTHKHVAQLSPYCVYRNRRTPAQPPTWVLYHRFSISKDNCLCTVSEIQPEMLVELAPPYFLSNLPPSESRDLLNQLREGTEPSAAVTETASPQEYGDGCVLQ", "length": 718 }, "evidence": [ { "id": "A0A9J7KCE9", "url": "https://omabrowser.org/oma/group/A0A9J7KCE9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LG93-1", "protein_name": "ATP-dependent RNA helicase homolog DQX1", "gene_name": "DQX1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASQLLRLEESGPNPGESELAGNPFDGLPFSSRYYELLEQRRALPVWAARFIFLEQLESSPSGVVLVSGEPGSGKSTQIPQWCAEFVLARGFQKGRVTVTQPYPLAARSLALRVADEMDLTLGHEVGYSIPQEDCTGPDTLLRFCWDRLLLQEVASTRGTGAWGVLVLDEAQERSVASDLLQGLLRDARLGNLPGDARVVVITDPAFEPKLQAFWGNPPIVHVPREPGRWPIPVYRDTVPTDRVEAACQAVLKLCQKEAPGDVLVYLPSEEEISLCCESLSREVGSLENQGPPPRVLPLHPGRGQAVQAVYEDTDSGARKVVVTHWLADFSFSLPSVRHVIDSGLELRSVYNPQIRAESQVLRPISKCQAEARRLRATGVPPGSCLCLYPKSFLELEAPPLPQPRVCEENLSPLVLLLKRRQIAEPGKCDFLDRPAPEALMQALEDLDYLAALDDDGDLSDLGIILSEFPLAPELAKALLASCEFNCVDEMLTLAAMLTAAPGFTRPPLCAEEAALRRALEHVDGDHSSLIQVYEAFIQSGADEAWCQARGLNWAALCQACKLRGELLELMQRIELPLSPPAFGSEQNRRDLQKALVSGYFLKVARDTDGTGNYLLLTHKHVAQLSPYCCYRNRRAPARPPPWVLYHNFSISKDNCLSIVSEIQPEMLVELAPPYFLSNLPPSESRDLLNQLREEMADSSMGSDSSSTQELGHACVLQ", "length": 718 }, "evidence": [ { "id": "A0A9J7KCE9", "url": "https://omabrowser.org/oma/group/A0A9J7KCE9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3ZBE0-1", "protein_name": "ATP-dependent RNA helicase homolog DQX1", "gene_name": "DQX1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASQLLGLEEESGPNPEESELAVNPFDGLPFSSRYYKLLEQRRSLPVWAARFIFLEHLESSPSGVVLVSGEPGCGKSTQIPQWCAEFVLARGFQKGWVTVTQPYPLAALSLALRVADEMDLTLGHEVGYSIPQEDCTGPDTLLRFCWDRLLLQEVASTRGTGARGVLILDEAQERSVASDLLQGLLRDARLGSLPGDLRVVVVTDPSLEPKLQDFWGGPPTVCVPRKTGSCPTPVYRDSLPADRVDAACQAVLEWCQEEAPGDVLVYLPSEEEISLCCESLSRKVRSLENQGPPPRVLPLHPGCGQAVQAVYEDTESGARKVVVTHWLADFSFSLPSIRHVIDSGLELRSVYSPQIRAESQVLRPVSKCQAEARRLRAAGIPPGSCLCLYPKSFLELEAPYLPQPRVWAENLSSLMLLLKRRQIAEPGKCHFLDRPAPEALMQALEDLDYLAALDDDGDLSDLGVILSEFPLAPELAKALLASCEFDCVDEMLTLAAMLTAAPGFTRPPVCAEEAALRRALEHVDGDHSSLIQVYEAFIQSGADKAWCQARGLNWAALCQARKLRGELLELMQRIELPLSQPAFGSERNRRDLQKALVSGYFLKVARDTDGTGNYLLLTHKHVAQLSPNCCYRSRRAPARPPLWVLYHSFSISKDNCLSIVSEIQPQMLVELAPPYFLSNLPPSESRDFLNQLREERTDSSIRSESSSTQELENACALQ", "length": 719 }, "evidence": [ { "id": "A0A9J7KCE9", "url": "https://omabrowser.org/oma/group/A0A9J7KCE9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8TE96-1", "protein_name": "ATP-dependent RNA helicase homolog DQX1", "gene_name": "DQX1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSQPLRLAEEYGPSPGESELAVNPFDGLPFSSRYYELLKQRQALPIWAARFTFLEQLESNPTGVVLVSGEPGSGKSTQIPQWCAEFALARGFQKGQVTVTQPYPLAARSLALRVADEMDLTLGHEVGYSIPQEDCTGPNTLLRFCWDRLLLQEVASTRGTGAWGVLVLDEAQERSVASDSLQGLLQDARLEKLPGDLRVVVVTDPALEPKLRAFWGNPPIVHIPREPGERPSPIYWDTIPPDRVEAACQAVLELCRKELPGDVLVFLPSEEEISLCCESLSREVESLLLQGLPPRVLPLHPDCGRAVQAVYEDMDARKVVVTHWLADFSFSLPSIQHVIDSGLELRSVYNPRIRAEFQVLRPISKCQAEARRLRARGFPPGSCLCLYPKSFLELEAPPLPQPRVCEENLSSLVLLLKRRQIAEPGECHFLDQPAPEALMQALEDLDYLAALDDDGDLSDLGVILSEFPLAPELAKALLASCEFDCVDEMLTLAAMLTAAPGFTRPPLSAEEAALRRALEHTDGDHSSLIQVYEAFIQSGADEAWCQARGLNWAALCQAHKLRGELLELMQRIELPLSLPAFGSEQNRRDLQKALVSGYFLKVARDTDGTGNYLLLTHKHVAQLSSYCCYRSRRAPARPPPWVLYHNFTISKDNCLSIVSEIQPQMLVELAPPYFLSNLPPSESRDLLNQLREGMADSTAGSKSSSAQEFRDPCVLQ", "length": 717 }, "evidence": [ { "id": "A0A9J7KCE9", "url": "https://omabrowser.org/oma/group/A0A9J7KCE9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q924H9-1", "protein_name": "ATP-dependent RNA helicase homolog DQX1", "gene_name": "Dqx1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASGLAEESELSPGESELAVNPFDGLPFSSCYYELLEQRRALPIWAARFLFLEHLESSPTGVVLVSGDPGSGKSTQIPQWCAEFALARGFQTGQVTVTQPYPLAAMSLASRVADEMDLTLGHEIGYSIPQEDCTGPNTMLRFCWDRLFLQEVASTRGPGAWSVLILDEAQERSVASDLLQGLLRDTRLRNLPGDPRVVVVTDPALEPKFQAFWGNSPIVRVPREPGGDPTLAYKDTVPTDLVEAACQAVLELCQQEEAPGDVLVYLPSEEEISLCCESLSGEMGTLAVPGPPPRVLPLHPGCAQAIQTVYEDTDVSVRKIVVTHWLADFSFSLPSIQHVIDSGLELRSVYNPRIRAESQVLRPISKCQAEARLLRAKGFPPGSCLRLYSKSTLELEAPPLPHPKVCEENLSSLVLLLMRKQIAEPGECHFLDRPAPEALMRALEDLDYLAALNDDGELSDLGVILSEFPLPPELAKALLASCEFNCVDEMLTLAAMLTAAPGFTRPPLSAGEAALRRALEHADGDHSSLIQVYEAFVQSGADEAWCQARGLNWESLCQARKLRAELVELMQRIELPLSQPAFGSEQNRRDLQKALLSGYFLKVARDTDGTGNYLLLTHKHVAQLSPYCSYRNRRTPAQPPTWVLYHSFSISKDNCLCIVSEIQPEMLVELAPPYFLSNLPPSESRDLLNQLREGTAEPPAAATETSSPQEYGDGCVLQ", "length": 718 }, "evidence": [ { "id": "A0A9J7KCE9", "url": "https://omabrowser.org/oma/group/A0A9J7KCE9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCE9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE9" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCE9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE9" } ], "pmid": "" }, { "name": "helicase activity", "id": "GO:0004386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004386", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCE9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "spliceosomal complex", "id": "GO:0005681", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005681", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCE9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 470, "end_pos": 472, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7KCE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE9" }, { "id": "PS51192", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51192" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Helicase ATP-binding", "eco_id": "ECO_0000259", "start_pos": 115, "end_pos": 283, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 470, "end_pos": 472 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7KAY7-1", "uniprot_ac": "A0A9J7KAY7", "uniprot_id": "A0A9J7KAY7_CRIGR", "mass": { "chemical_mass": 64039.0, "monoisotopic_mass": 64039.0 }, "refseq": { "ac": "XP_035293354", "name": "sodium-dependent phosphate transport protein 2C isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293354" }, "gene_names": [ { "name": "Slc34a3", "type": "recommended", "evidence": [ { "id": "A0A9J7KAY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAY7" } ] }, { "name": "Slc34a3", "type": "synonym", "evidence": [ { "id": "XP_035293354", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293354" } ] } ], "protein_names": [ { "name": "Sodium-dependent phosphate transport protein 2C isoform X3", "type": "synonym", "evidence": [ { "id": "A0A9J7KAY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAY7/entry#names_and_taxonomy" } ] }, { "name": "sodium-dependent phosphate transport protein 2C isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035293354", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293354" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616080.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035293354", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293354" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAY7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Slc34a3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAY7", "locus": {} } ], "crossref": [ { "id": "A0A9J7KAY7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7KAY7", "database": "AlphaFoldDB", "categories": [] }, { "id": "100773189", "url": "https://www.ncbi.nlm.nih.gov/gene/100773189", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773189", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773189", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VHSIFNW", "url": "https://omabrowser.org/oma/group/VHSIFNW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7KAY7", "url": "https://www.orthodb.org/?gene=A0A9J7KAY7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10010", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10010", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10010:SF35", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10010:SF35", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035293354", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293354", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H4E9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4E9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H4E9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4E9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAY7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPNSLAGGQFPNPTLDAIDLEDRNPRNAGTSSSIPGLEEGSTDPWAFPQLKNTGQLKEVSMASRLRKVVIGFLKLCGLLGSLYFFICSLDILSSAFQLLGSKMAGDIFKDNVVLSNPVAGLVIGVLVTVLVQSSSTSSSIVVSMVASKLLTVQVSVPIIMGVNVGTSITSTLVSMAQSGDRDEFQRAFSGSAVHGIFNWLTVLVLLPLECATAALERLSELALGAASLQPGGQAPDILKALTQPFTHLIIQLDSSVITGSATSNNTNSSLIKQWCGVREETPQGSNEECSIFNPCTENSTASPEESKVPCNHLFVGTGLTDLAVGFILLAGSLLVLCTCLVLIVKLLNSVLQGRIAQAVRTVINADFPFPFGWLSGYLAILVGAGLTFLLQSSSVFTAAIVPLMGVGVINLERAYPLFLGSNIGTTTTALLAALASPADMMLFAVQVALIHFFFNLAGILLWYLVPVLRLPIPLAKRFGDLTAQYRWVAIVYLLFTFLLLPLAAFGLSLAGGSVLAAVGGPLVGLVLLIILVNILQRHRPSWLPHCLRSWAWLPLWLHSLEPWDRLVTGCCPCRACKSNSSMASKVANCYENPEIIASQQL", "length": 601, "header": "tr|A0A9J7KAY7-1|A0A9J7KAY7_CRIGR Isoform 1 of Sodium-dependent phosphate transport protein 2C isoform X3 OS=Cricetulus griseus OX=10029 GN=Slc34a3 PE=3 SV=1 CANONICAL=A0A9J7KAY7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H4E9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAY7/entry#A0A9J7H4E9-1", "sequence": { "sequence": "MPNSLAGGQFPNPTLDAIDLEDRNPRNAGTSSSIPGLEEGSTDPWAFPQLKNTGQLKEVSMASRLRKVVIGFLKLCGLLGSLYFFICSLDILSSAFQLLGSKMAGDIFKDNVVLSNPVAGLVIGVLVTVLVQSSSTSSSIVVSMVASKLLTVQVSVPIIMGVNVGTSITSTLVSMAQSGDRDEFQRAFSGSAVHGIFNWLTVLVLLPLECATAALERLSELALGAASLQPGGQAPDILKALTQPFTHLIIQLDSSVITGSATSNNTNSSLIKQWCGATPQPQGSNEECSIFNPCTENSTASPEESKVPCNHLFVGTGLTDLAVGFILLAGSLLVLCTCLVLIVKLLNSVLQGRIAQAVRTVINADFPFPFGWLSGYLAILVGAGLTFLLQSSSVFTAAIVPLMGVGVINLERAYPLFLGSNIGTTTTALLAALASPADMMLFAVQVALIHFFFNLAGILLWYLVPVLRLPIPLAKRFGDLTAQYRWVAIVYLLFTFLLLPLAAFGLSLAGGSVLAAVGGPLVGLVLLIILVNILQRHRPSWLPHCLRSWAWLPLWLHSLEPWDRLVTGCCPCRACKSNSSMASKVANCYENPEIIASQQL", "length": 600, "header": "tr|A0A9J7H4E9-1|A0A9J7H4E9_CRIGR Computationally mapped isoform of Sodium-dependent phosphate transport protein 2C isoform X2 OS=Cricetulus griseus OX=10029 GN=Slc34a3 PE=3 SV=1 CANONICAL=A0A9J7KAY7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KAY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAY7/entry#A0A9J7KAY7-1", "sequence": { "sequence": "MPNSLAGGQFPNPTLDAIDLEDRNPRNAGTSSSIPGLEEGSTDPWAFPQLKNTGQLKEVSMASRLRKVVIGFLKLCGLLGSLYFFICSLDILSSAFQLLGSKMAGDIFKDNVVLSNPVAGLVIGVLVTVLVQSSSTSSSIVVSMVASKLLTVQVSVPIIMGVNVGTSITSTLVSMAQSGDRDEFQRAFSGSAVHGIFNWLTVLVLLPLECATAALERLSELALGAASLQPGGQAPDILKALTQPFTHLIIQLDSSVITGSATSNNTNSSLIKQWCGVREETPQGSNEECSIFNPCTENSTASPEESKVPCNHLFVGTGLTDLAVGFILLAGSLLVLCTCLVLIVKLLNSVLQGRIAQAVRTVINADFPFPFGWLSGYLAILVGAGLTFLLQSSSVFTAAIVPLMGVGVINLERAYPLFLGSNIGTTTTALLAALASPADMMLFAVQVALIHFFFNLAGILLWYLVPVLRLPIPLAKRFGDLTAQYRWVAIVYLLFTFLLLPLAAFGLSLAGGSVLAAVGGPLVGLVLLIILVNILQRHRPSWLPHCLRSWAWLPLWLHSLEPWDRLVTGCCPCRACKSNSSMASKVANCYENPEIIASQQL", "length": 601, "header": "tr|A0A9J7KAY7-1|A0A9J7KAY7_CRIGR Isoform 1 of Sodium-dependent phosphate transport protein 2C isoform X3 OS=Cricetulus griseus OX=10029 GN=Slc34a3 PE=3 SV=1 CANONICAL=A0A9J7KAY7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAY7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAY7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773189", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773189", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q80SU6-1", "protein_name": "Sodium-dependent phosphate transport protein 2C", "gene_name": "Slc34a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPNSLAGGQVPNPTLDAFDLVDRSLRNAGISGSIPGLEEGGTDPWTFSPLKNADQLKEVGMASRLRRVVSSFLKACGLLGSLYFFICSLDILSSAFQLLGSKMAGDIFKDNVVLSNPVAGLVIGVLVTVLVQSSSTSSSIVVSMVASKLLTVQVSVPIIMGVNVGTSITSTLVSMAQSGDRDEFQRAFSGSAVHGIFNWLTVLVLLPLESATAALERLSELALGAASLQPGQQAPDILKALTRPFTHLIIQLDSSVITSGITSNTTNSSLIKHWCGFRGETPQGSSEGCGLFSSCTERNSSASPEEDRLLCHHLFAGSKLTDLAVGFILLAGSLLVLCVCLVLIVKLLNSVLKGRIAQAVKTVINADFPFPFGWLSGYLAILVGAGLTFLLQSSSVFTAAIVPLMGVGVIDLERAYPLFLGSNIGTTTTALLAALASPADMLIFAVQVALIHFFFNLAGILLWYLVPVLRLPIPLAKRFGNLTAQYRWVAIVYLLLTFLLLPLAAFGLSLAGGTVLAAVGGPLVGLVLLIILVNVLQQHRPSWLPRCLQSWAWLPLWLHSLEPWDRLVTACCPCRACSNSPMTSKVAHCYENPQVIASQQL", "length": 601 }, "evidence": [ { "id": "A0A9J7KAY7", "url": "https://omabrowser.org/oma/group/A0A9J7KAY7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N130-1", "protein_name": "Sodium-dependent phosphate transport protein 2C", "gene_name": "SLC34A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPSSLPGSQVPHPTLDAVDLVEKTLRNEGTSSSAPVLEEGDTDPWTLPQLKDTSQPWKELRVAGRLRRVAGSVLKACGLLGSLYFFICSLDVLSSAFQLLGSKVAGDIFKDNVVLSNPVAGLVIGVLVTALVQSSSTSSSIVVSMVAAKLLTVRVSVPIIMGVNVGTSITSTLVSMAQSGDRDEFQRAFSGSAVHGIFNWLTVLVLLPLESATALLERLSELALGAASLTPRAQAPDILKVLTKPLTHLIVQLDSDMIMSSATGNATNSSLIKHWCGTTGQPTQENSSCGAFGPCTEKNSTAPADRLPCRHLFAGTELTDLAVGCILLAGSLLVLCGCLVLIVKLLNSVLRGRVAQVVRTVINADFPFPLGWLGGYLAVLAGAGLTFALQSSSVFTAAVVPLMGVGVISLDRAYPLLLGSNIGTTTTALLAALASPADRMLSALQVALIHFFFNLAGILLWYLVPALRLPIPLARHFGVVTARYRWVAGVYLLLGFLLLPLAAFGLSLAGGMELAAVGGPLVGLVLLVILVTVLQRRRPAWLPVRLRSWAWLPVWLHSLEPWDRLVTRCCPCNVCSPPKATTKEAYCYENPEILASQQL", "length": 599 }, "evidence": [ { "id": "A0A9J7KAY7", "url": "https://omabrowser.org/oma/group/A0A9J7KAY7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "brush border", "id": "GO:0005903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005903", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAY7" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAY7" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAY7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "sodium:phosphate symporter activity", "id": "GO:0005436", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005436", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAY7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular phosphate ion homeostasis", "id": "GO:0030643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030643", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAY7" } ], "pmid": "" }, { "name": "sodium-dependent phosphate transport", "id": "GO:0044341", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044341", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KAY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAY7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 267, "end_pos": 269, "annotation": "n_glycosylation_sequon" }, { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 579, "end_pos": 581, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], 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"Protein Classification" ] }, { "id": "cge:100758326", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758326", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KB20", "url": "https://www.orthodb.org/?gene=A0A9J7KB20", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45636", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45636", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45636:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45636:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00292", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00292", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12403", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12403", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035302968", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302968", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KB20", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KB20-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB20-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASEGSEEQVQEQMWGGAYTIVPAFPGVSPNTYHLVLTIVPDNPVFLGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGLLGIAQPGSDNKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLDCPFERQHYSEAYASPSHTKGEQGLYPLPLLNSALDDGKATLTPSNTPLGRNLSTHQTYPVVADPHSPFAIKQETPELSSSSSTPSSLSSSAFLDLQQVGSGGPAGASVPPFNAFPHAASVYGQFTGQALLSGREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYSHTPYSSYSEAWRFPNSSLLSSPYYYSSTTRPSAPPTSATAFDHL", "length": 496, "header": "tr|A0A9J7KB20-1|A0A9J7KB20_CRIGR Isoform 1 of Paired box protein Pax-8 OS=Cricetulus griseus OX=10029 GN=Pax8 PE=4 SV=1 CANONICAL=A0A9J7KB20-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KB20-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB20/entry#A0A9J7KB20-1", "sequence": { "sequence": "MASEGSEEQVQEQMWGGAYTIVPAFPGVSPNTYHLVLTIVPDNPVFLGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTYSINGLLGIAQPGSDNKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDAFSQHHLEPLDCPFERQHYSEAYASPSHTKGEQGLYPLPLLNSALDDGKATLTPSNTPLGRNLSTHQTYPVVADPHSPFAIKQETPELSSSSSTPSSLSSSAFLDLQQVGSGGPAGASVPPFNAFPHAASVYGQFTGQALLSGREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYSHTPYSSYSEAWRFPNSSLLSSPYYYSSTTRPSAPPTSATAFDHL", "length": 496, "header": "tr|A0A9J7KB20-1|A0A9J7KB20_CRIGR Isoform 1 of Paired box protein Pax-8 OS=Cricetulus griseus OX=10029 GN=Pax8 PE=4 SV=1 CANONICAL=A0A9J7KB20-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 205, "start_aa": "Thr", "end_pos": 205, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr205", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 360, "start_aa": "Thr", "end_pos": 360, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr360", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KB20", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB20" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KB20", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB20" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758326", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758326", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KB20", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB20" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KB20", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB20" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KB20", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB20" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KB20", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB20" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KB20", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB20" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 467, "end_pos": 469, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7KB20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB20" }, { "id": "PS51057", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51057" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Paired", "eco_id": "ECO_0000259", "start_pos": 48, "end_pos": 174, "start_aa": "Gly", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 205, 360 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 158, "end_pos": 160 }, { "start_pos": 328, "end_pos": 330 }, { "start_pos": 467, "end_pos": 469 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", 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], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"uniprot_canonical_ac": "A0A9J7KB25-1", "uniprot_ac": "A0A9J7KB25", "uniprot_id": "A0A9J7KB25_CRIGR", "mass": { "chemical_mass": 87949.0, "monoisotopic_mass": 87949.0 }, "refseq": { "ac": "XP_035304844", "name": "CD177 antigen isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304844" }, "gene_names": [ { "name": "LOC100753760", "type": "recommended", "evidence": [ { "id": "A0A9J7KB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB25" } ] }, { "name": "LOC100753760", "type": "synonym", "evidence": [ { "id": "XP_035304844", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304844" } ] } ], "protein_names": [ { "name": "CD177 antigen isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035304844", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304844" }, { "id": "A0A9J7KB25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB25/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304844", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304844" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KB25", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB25" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100753760", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB25", "locus": {} } ], "crossref": [ { "id": "A0A9J7KB25", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7KB25", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd23623", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23623", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23624", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23624", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23636", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23636", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23637", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23637", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100753760", "url": "https://www.ncbi.nlm.nih.gov/gene/100753760", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016054", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016054", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753760", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753760", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KB25", "url": "https://www.orthodb.org/?gene=A0A9J7KB25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16529", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16529", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16529:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16529:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00021", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00021", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304844", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304844", 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"MNLTPVLTLLGVTVLLPCVPALSCRRATIETVRNASELPLEWKTGEKTCEVGEGCQDLVMLLENGPRINLVIIKDCVKAEDQEPRVTWLRTGPGLSIVSYTRVCRHSDFCNDVSSTEVLGDLPSPTVPGTLRCPLCLSKDGCEDTLEQVCPIGSTHCYNGVLRLRGAHITTNLRVQGCMPQPDCNLLNGTKAIGTLDVSENCGLQLGPQALDCNSVALDTVRNVSDLHLSWTTDWKTCEAGQGCQETLMLIQNGQEFHMVLTKGCTSDANRKPEITRHRTGPGISIITYVHVCRHGDFCNDLSTTRNLWTPHPDTVPGTLSCPHCLSTRGCEQASQQACPAGSSHCYNGVLRLRGGGLISDLKVQGCMSQPGCNLLNGTQIIGPIDVREDCGFQLGALKCQHGTLEITRDVSQLPLQWTAGQTTCDVGEGCQDTLMMIENGEQVYLSLTKGCTTTEDQEAKVTEHRTGPGLSVTSYTRVCRLRDLCNDLYTTAPLWAPPPAAAPGTLLCPLCFSKDDCGNPPRQVCPAGSTHCYHGVLRLRGGEITSNLRVQGCMSQPGCSLLNGTQKIGPMDVREDCSPPSTDTVTCYKGTMLRLGVGFATEAVQWSVSATQVCEPEETCQETLLLVDIGPRTLLIGSKGCARARAEDKVDISIHSSPPGMLVASYSVFCSSDRCNEASNSSVLLSRLPRLTAPPPGDLQCPVCVEFFGSCFGSTNFVTCPQGTSHCYQGDIVLQGGGVSSTVSLQGCMSSPAKTLLGGSKSIGVFSVKELSEGTKDLPEDENDKNPLGGGASASSLTWLLGLGIVLALCLSSFVLSAEPIPL", "length": 824, "header": "tr|A0A9J7KB25-1|A0A9J7KB25_CRIGR Isoform 1 of CD177 antigen isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100753760 PE=4 SV=1 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Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035303249", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303249" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KB53", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB53" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100769794", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB53", "locus": {} } ], "crossref": [ { "id": "A0A9J7KB53", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7KB53", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd20982", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20982", "database": "CDD", "categories": [ "Protein 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"url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KB54", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KB54", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KB54", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { 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"A0A8C2N3U2-1", "A0A8C2M4P9-1", "A0A8C2QHS8-1", "A0A8C2QIA1-1", "A0A8C2QMB3-1", "A0A9J7F8T9-1", "A0A9J7FN52-1", "O55076-1", "P68180-1", "A0A061IJW6-1", "A0A3L7HQF4-1", "A0A3L7HRZ8-1", "A0A8C2LI15-1", "A0A8C2M497-1", "A0A8C2MAD7-1", "G3HBD4-1", "P25321-1", "A0A8C2MBP2-1", "A0A9J7JGR2-1", "A0A8C2QLT0-1", "G3HDE8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HUS7", "gene_name": "Srpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] } ] }, { "uniprot_ac": "A0A061HVM6", "gene_name": "Hipk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] } ] }, { "uniprot_ac": "A0A061HZ27", "gene_name": "Pik3cg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] } ] }, { "uniprot_ac": "A0A061I033", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] } ] }, { "uniprot_ac": "A0A061I8L6", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] } ] }, { "uniprot_ac": "A0A061I9F9", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] } ] }, { "uniprot_ac": "A0A061IJA8", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] } ] }, { "uniprot_ac": "A0A061IJW6", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] } ] }, { "uniprot_ac": "A0A061ILI7", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] } ] }, { "uniprot_ac": "A0A3L7GMP6", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] } ] }, { "uniprot_ac": "A0A3L7GPC7", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] } ] }, { "uniprot_ac": "A0A3L7HK04", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] } ] }, { "uniprot_ac": "A0A3L7HKC4", "gene_name": "Cdkl4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] } ] }, { "uniprot_ac": "A0A3L7HMX8", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] } ] }, { "uniprot_ac": "A0A3L7HQF4", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] } ] }, { "uniprot_ac": "A0A3L7HRZ8", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] } ] }, { "uniprot_ac": "A0A3L7HV37", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] } ] }, { "uniprot_ac": "A0A3L7I1E7", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0A3L7I1E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1E7" } ] } ] }, { "uniprot_ac": "A0A3L7I1R2", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] } ] }, { "uniprot_ac": "A0A3L7I4E3", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] } ] }, { "uniprot_ac": "A0A3L7I5Y4", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] } ] }, { "uniprot_ac": "A0A3L7I870", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] } ] }, { "uniprot_ac": "A0A3L7IB60", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] } ] }, { "uniprot_ac": "A0A3L7IBX6", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] } ] }, { "uniprot_ac": "A0A3L7ID00", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] } ] }, { "uniprot_ac": "A0A3L7IEL5", "gene_name": "LOC113833388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] } ] }, { "uniprot_ac": "A0A3L7IER1", "gene_name": "Stk38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] } ] }, { "uniprot_ac": "A0A8C2L7R1", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] } ] }, { "uniprot_ac": "A0A8C2LA64", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] } ] }, { "uniprot_ac": "A0A8C2LC89", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] } ] }, { "uniprot_ac": "A0A8C2LCN7", "gene_name": "Csnk2a2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] } ] }, { "uniprot_ac": "A0A8C2LDE5", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] } ] }, { "uniprot_ac": "A0A8C2LDQ8", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] } ] }, { "uniprot_ac": "A0A8C2LDU9", "gene_name": "Ern1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] } ] }, { "uniprot_ac": "A0A8C2LE67", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] } ] }, { "uniprot_ac": "A0A8C2LEI8", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] } ] }, { "uniprot_ac": "A0A8C2LFT9", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] } ] }, { "uniprot_ac": "A0A8C2LH99", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] } ] }, { "uniprot_ac": "A0A8C2LHE9", "gene_name": "Camk1d", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] } ] }, { "uniprot_ac": "A0A8C2LI14", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] } ] }, { "uniprot_ac": "A0A8C2LI15", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] } ] }, { "uniprot_ac": "A0A8C2LII0", "gene_name": "Cdk6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] } ] }, { "uniprot_ac": "A0A8C2LK72", "gene_name": "Rps6ka4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] } ] }, { "uniprot_ac": "A0A8C2LMC9", "gene_name": "Mknk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] } ] }, { "uniprot_ac": "A0A8C2LMJ0", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] } ] }, { "uniprot_ac": "A0A8C2LPE9", "gene_name": "Mast3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": 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[ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] } ] }, { "uniprot_ac": "A0A8C2LTT6", "gene_name": "Prkd2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] } ] }, { "uniprot_ac": "A0A8C2LTW4", "gene_name": "Dclk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] } ] }, { "uniprot_ac": "A0A8C2LTZ7", "gene_name": "Tssk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] } ] }, { "uniprot_ac": "A0A8C2LVR4", "gene_name": "LOC100775051", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", 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"url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] } ] }, { "uniprot_ac": "A0A8C2LY52", "gene_name": "Dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] } ] }, { "uniprot_ac": "A0A8C2LZT2", "gene_name": "Uhmk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] } ] }, { "uniprot_ac": "A0A8C2M0A2", "gene_name": "Mapk4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] } ] }, { "uniprot_ac": "A0A8C2M165", "gene_name": "Cdk4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] } ] }, { "uniprot_ac": "A0A8C2M187", "gene_name": "Map2k2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] } ] }, { "uniprot_ac": "A0A8C2M1F6", "gene_name": "Cdk19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] } ] }, { "uniprot_ac": "A0A8C2MAD7", "gene_name": "Pim1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] } ] }, { "uniprot_ac": "A0A8C2MB66", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] } ] }, { "uniprot_ac": "A0A8C2MBI9", "gene_name": "Tnk1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] } ] }, { "uniprot_ac": "A0A8C2MBP2", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] } ] }, { "uniprot_ac": "A0A8C2MBW2", "gene_name": "Tp53rk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] } ] }, { "uniprot_ac": "A0A8C2MC09", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] } ] }, { "uniprot_ac": "A0A8C2MCI5", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] } ] }, { "uniprot_ac": "A0A8C2MCX3", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] } ] }, { "uniprot_ac": "A0A8C2MEU5", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] } ] }, { "uniprot_ac": "A0A8C2MFN1", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] } ] }, { "uniprot_ac": "A0A8C2MH43", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] } ] }, { "uniprot_ac": "A0A8C2MJ02", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] } ] }, { "uniprot_ac": "A0A8C2ML15", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] } ] }, { "uniprot_ac": "A0A8C2MMI4", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] } ] }, { "uniprot_ac": "A0A8C2MMQ4", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] } ] }, { "uniprot_ac": "A0A8C2MMZ5", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] } ] }, { "uniprot_ac": "A0A8C2MP62", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] } ] }, { "uniprot_ac": "A0A8C2MQ42", "gene_name": "Cdkl5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] } ] }, { "uniprot_ac": "A0A8C2MQ73", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] } ] }, { "uniprot_ac": "A0A8C2MQL9", "gene_name": "LOC100766643", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] } ] }, { "uniprot_ac": "A0A8C2MQM0", "gene_name": "Camkk2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] } ] }, { "uniprot_ac": "A0A8C2MQS3", "gene_name": "Taok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] } ] }, { "uniprot_ac": "A0A8C2MR08", "gene_name": "Stk36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] } ] }, { "uniprot_ac": "A0A8C2MSQ2", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] } ] }, { "uniprot_ac": "A0A8C2MTI7", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] } ] }, { "uniprot_ac": "A0A8C2MUQ5", "gene_name": "Mapkapk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] } ] }, { "uniprot_ac": "A0A8C2MV78", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] } ] }, { "uniprot_ac": "A0A8C2MYH0", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] } ] }, { "uniprot_ac": "A0A8C2N0J6", "gene_name": "Camk4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0J6" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2N0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0J6" } ] } ] }, { "uniprot_ac": "A0A8C2N185", "gene_name": "Mak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N185" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N185" } ] } ] }, { "uniprot_ac": "A0A8C2N210", "gene_name": "Nek10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N210" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N210" } ] } ] }, { "uniprot_ac": "A0A8C2N310", "gene_name": "Rps6kl1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] } ] }, { "uniprot_ac": "A0A8C2N3C9", "gene_name": "LOC100773612", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3C9", "database": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QHS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QHS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHS8" } ] } ] }, { "uniprot_ac": "A0A8C2QI80", "gene_name": "Mapk3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QI80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QI80" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2QI80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QI80" } ] } ] }, { "uniprot_ac": "A0A8C2QIA1", "gene_name": "Prkce", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { 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"ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2QL63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QL63" } ] } ] }, { "uniprot_ac": "A0A8C2QLT0", "gene_name": "Nek9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QLT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLT0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8C2QLT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLT0" } ] } ] }, { "uniprot_ac": "A0A8C2QMB3", "gene_name": "Mapk1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMB3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2QMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMB3" } ] } ] }, { "uniprot_ac": "A0A8C2QND0", "gene_name": "Sgk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QND0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QND0" } ] } ] }, { "uniprot_ac": "A0A8C2QNX2", "gene_name": "Taok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QNX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QNX2", "database": "UniProtKB", "url": 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H(+).", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] } ] }, { "uniprot_ac": "A0A9J7F0N6", "gene_name": "LOC100770091", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] } ] }, { "uniprot_ac": "A0A9J7F0Y2", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0Y2", "database": 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} ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7F2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2F1" } ] } ] }, { "uniprot_ac": "A0A9J7F2L0", "gene_name": "Ripk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] } ] }, { "uniprot_ac": "A0A9J7F383", "gene_name": "LOC113833167", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] } ] }, { "uniprot_ac": "A0A9J7F3R3", "gene_name": "Braf", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] } ] }, { "uniprot_ac": "A0A9J7F4P4", "gene_name": "Tnni3k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] } ] }, { "uniprot_ac": "A0A9J7F5B0", "gene_name": "Plk4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] } ] }, { "uniprot_ac": "A0A9J7F773", "gene_name": "Pklr", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] } ] }, { "uniprot_ac": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] } ] }, { "uniprot_ac": "A0A9J7F8T0", "gene_name": "Pask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T0" } ] } ] }, { "uniprot_ac": "A0A9J7F8T9", "gene_name": "Mtor", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] } ] }, { "uniprot_ac": "A0A9J7F8V5", "gene_name": "Nek3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] } ] }, { "uniprot_ac": "A0A9J7F927", "gene_name": "Map3k12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] } ] }, { "uniprot_ac": "A0A9J7F985", "gene_name": "LOC118237656", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] } ] }, { "uniprot_ac": "A0A9J7F9C4", "gene_name": "Nek5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] } ] }, { "uniprot_ac": "A0A9J7FBT0", "gene_name": "Speg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] } ] }, { "uniprot_ac": "A0A9J7FC43", "gene_name": "Cdk15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] } ] }, { "uniprot_ac": "A0A9J7FC95", "gene_name": "Lrrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": 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"L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] } ] }, { "uniprot_ac": "A0A9J7FF13", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] } ] }, { "uniprot_ac": "A0A9J7FF35", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] } ] }, { "uniprot_ac": "A0A9J7FFS7", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] } ] }, { "uniprot_ac": "A0A9J7FGD3", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] } ] }, { "uniprot_ac": "A0A9J7FGF7", "gene_name": "LOC100751450", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] } ] }, { "uniprot_ac": "A0A9J7FI14", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FKM1", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] } ] }, { "uniprot_ac": "A0A9J7FKM9", "gene_name": "LOC113834545", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] } ] }, { "uniprot_ac": "A0A9J7FLY5", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] } ] }, { "uniprot_ac": "A0A9J7FN24", "gene_name": "Alpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] } ] }, { "uniprot_ac": "A0A9J7FN52", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] } ] }, { "uniprot_ac": "A0A9J7FN68", "gene_name": "Mast1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] } ] }, { "uniprot_ac": "A0A9J7FNF0", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] } ] }, { "uniprot_ac": "A0A9J7FS53", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] } ] }, { "uniprot_ac": "A0A9J7FUL0", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] } ] }, { "uniprot_ac": "A0A9J7FVR6", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] } ] }, { "uniprot_ac": "A0A9J7FYJ6", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FYY3", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] } ] }, { "uniprot_ac": "A0A9J7FZ18", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] } ] }, { "uniprot_ac": "A0A9J7FZA7", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] } ] }, { "uniprot_ac": "A0A9J7FZH7", "gene_name": "LOC113835540", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] } ] }, { "uniprot_ac": "A0A9J7FZW1", "gene_name": "Mok", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] } ] }, { "uniprot_ac": "A0A9J7FZY8", "gene_name": "Pik3cb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] } ] }, { "uniprot_ac": "A0A9J7G180", "gene_name": "Dstyk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] } ] }, { "uniprot_ac": "A0A9J7G1D9", "gene_name": "Ulk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] } ] }, { "uniprot_ac": "A0A9J7G1H0", "gene_name": "Map4k5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] } ] }, { "uniprot_ac": "A0A9J7G270", "gene_name": "LOC100754226", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] } ] }, { "uniprot_ac": "A0A9J7G368", "gene_name": "Stk11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] } ] }, { "uniprot_ac": "A0A9J7G3C1", "gene_name": "Dapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] } ] }, { "uniprot_ac": "A0A9J7G4B8", "gene_name": "Cdk18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] } ] }, { "uniprot_ac": "A0A9J7G5F3", "gene_name": "Plk5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5F3" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5F3" } ] } ] }, { "uniprot_ac": "A0A9J7G5N9", "gene_name": "Stk35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] } ] }, { "uniprot_ac": "A0A9J7G6S5", "gene_name": "Trpm7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] } ] }, { "uniprot_ac": "A0A9J7G8N0", "gene_name": "LOC100770044", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G8N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N0" } ] } ] }, { "uniprot_ac": "A0A9J7G8N4", "gene_name": "Sgk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G8N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N4" } ] } ] }, { "uniprot_ac": "A0A9J7G969", "gene_name": "LOC100754771", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G969", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G969" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G969", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G969" } ] } ] }, { "uniprot_ac": "A0A9J7G9D1", "gene_name": "Hipk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G9D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G9D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D1" } ] } ] }, { "uniprot_ac": "A0A9J7GAB0", "gene_name": "Pkn3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GAB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB0" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GAB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB0" } ] } ] }, { "uniprot_ac": "A0A9J7GAF4", "gene_name": "Stk10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ] } ] }, { "uniprot_ac": "A0A9J7GBF4", "gene_name": "Csnk1d", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ] } ] }, { "uniprot_ac": "A0A9J7GBI2", "gene_name": "LOC100771767", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBI2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBI2" } ] } ] }, { "uniprot_ac": "A0A9J7GBL6", "gene_name": "Ttbk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GBL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6" } ] } ] }, { "uniprot_ac": "A0A9J7GD76", "gene_name": "Taok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD76" } ] } ] }, { "uniprot_ac": "A0A9J7GES8", "gene_name": "Tlk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] } ] }, { "uniprot_ac": "A0A9J7GF22", "gene_name": "Aatk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] } ] }, { "uniprot_ac": "A0A9J7GF26", "gene_name": "LOC100752478", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF26" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF26" } ] } ] }, { "uniprot_ac": "A0A9J7GF59", "gene_name": "LOC103160391", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] } ] }, { "uniprot_ac": "A0A9J7GFS3", "gene_name": "Aak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] } ] }, { "uniprot_ac": "A0A9J7GG74", "gene_name": "Cdkl3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] } ] }, { "uniprot_ac": "A0A9J7GGP1", "gene_name": "Map4k1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] } ] }, { "uniprot_ac": "A0A9J7GHB3", "gene_name": "Map2k4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] } ] }, { "uniprot_ac": "A0A9J7GHK2", "gene_name": "LOC100753695", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] } ] }, { "uniprot_ac": "A0A9J7GHV2", "gene_name": "LOC100773845", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] } ] }, { "uniprot_ac": "A0A9J7GI33", "gene_name": "Map3k10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] } ] }, { "uniprot_ac": "A0A9J7GIC4", "gene_name": "Stk26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] } ] }, { "uniprot_ac": "A0A9J7GIR8", "gene_name": "Prkcg", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": 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= O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] } ] }, { "uniprot_ac": "A0A9J7JJV6", "gene_name": "Mark1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] } ] }, { "uniprot_ac": "A0A9J7JKJ1", "gene_name": "Sik2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] } ] }, { "uniprot_ac": "A0A9J7JLH7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] } ] }, { "uniprot_ac": "A0A9J7JNT2", "gene_name": "LOC113835854", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] } ] }, { "uniprot_ac": "A0A9J7JNU2", "gene_name": "Tnk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] } ] }, { "uniprot_ac": "A0A9J7JPD7", "gene_name": "Lmtk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] } ] }, { "uniprot_ac": "A0A9J7JPE2", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] } ] }, { "uniprot_ac": "A0A9J7JPF2", "gene_name": "LOC100765388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] } ] }, { "uniprot_ac": "A0A9J7JPI2", "gene_name": "Ksr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] } ] }, { "uniprot_ac": "A0A9J7JPY1", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] } ] }, { "uniprot_ac": "A0A9J7JQD1", "gene_name": "Ulk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] } ] }, { "uniprot_ac": "A0A9J7JQV6", "gene_name": "Pkm", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] } ] }, { "uniprot_ac": "A0A9J7JQZ1", "gene_name": "Wnk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQZ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JQZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQZ1" } ] } ] }, { "uniprot_ac": "A0A9J7JRI3", "gene_name": "Cdc42bpb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] } ] }, { "uniprot_ac": "A0A9J7JRJ8", "gene_name": "Mark3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] } ] }, { "uniprot_ac": "A0A9J7JSB5", "gene_name": "LOC113836186", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] } ] }, { "uniprot_ac": "A0A9J7JTJ0", "gene_name": "LOC113838440", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] } ] }, { "uniprot_ac": "A0A9J7JTL3", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] } ] }, { "uniprot_ac": "A0A9J7JU24", "gene_name": "Camk2a", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] } ] }, { "uniprot_ac": "A0A9J7JXM2", "gene_name": "Dcaf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] } ] }, { "uniprot_ac": "A0A9J7JXX3", "gene_name": "Map3k3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] } ] }, { "uniprot_ac": "A0A9J7JYC5", "gene_name": "Nme7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] } ] }, { "uniprot_ac": "A0A9J7JYU7", "gene_name": "Mink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] } ] }, { "uniprot_ac": "A0A9J7JZS0", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] } ] }, { "uniprot_ac": "A0A9J7K1H4", "gene_name": "LOC113837295", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] } ] }, { "uniprot_ac": "A0A9J7K2Q7", "gene_name": "LOC100773089", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] } ] }, { "uniprot_ac": "A0A9J7K2S5", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] } ] }, { "uniprot_ac": "A0A9J7K3L1", "gene_name": "LOC100755238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] } ] }, { "uniprot_ac": "A0A9J7K3S4", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] } ] }, { "uniprot_ac": "A0A9J7K4N6", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] } ] }, { "uniprot_ac": "A0A9J7K6R5", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] } ] }, { "uniprot_ac": "A0A9J7K7C7", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] } ] }, { "uniprot_ac": "A0A9J7K7D8", "gene_name": "LOC100757073", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] } ] }, { "uniprot_ac": "A0A9J7K851", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] } ] }, { "uniprot_ac": "A0A9J7K8Y1", "gene_name": "Lmtk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] } ] }, { "uniprot_ac": "A0A9J7K953", "gene_name": "Cdkl1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] } ] }, { "uniprot_ac": "A0A9J7KB54", "gene_name": "LOC118237737", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] } ] }, { "uniprot_ac": "A0A9J7KC95", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] } ] }, { "uniprot_ac": "A0A9J7KCM5", "gene_name": "LOC113837018", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] } ] }, { "uniprot_ac": "A0A9J7KCN2", "gene_name": "LOC107977720", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] } ] }, { "uniprot_ac": "A0A9J7KDV7", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] } ] }, { "uniprot_ac": "A0A9J7KE81", "gene_name": "Nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] } ] }, { "uniprot_ac": "A0A9J7KFV8", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] } ] }, { "uniprot_ac": "G3GRI0", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] } ] }, { "uniprot_ac": "G3GRR1", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] } ] }, { "uniprot_ac": "G3GUA6", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] } ] }, { "uniprot_ac": "G3GVI7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] } ] }, { "uniprot_ac": "G3GWJ3", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] } ] }, { "uniprot_ac": "G3GWN1", "gene_name": "LOC100755333", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] } ] }, { "uniprot_ac": "G3GX92", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] } ] }, { "uniprot_ac": "G3GY19", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] } ] }, { "uniprot_ac": "G3GYQ3", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] } ] }, { "uniprot_ac": "G3H3C3", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] } ] }, { "uniprot_ac": "G3H3S6", "gene_name": "Lats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] } ] }, { "uniprot_ac": "G3H5L5", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] } ] }, { "uniprot_ac": "G3H8I4", "gene_name": "Lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] } ] }, { "uniprot_ac": "G3HAZ9", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] } ] }, { "uniprot_ac": "G3HBD4", "gene_name": "LOC100765914", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] } ] }, { "uniprot_ac": "G3HBI7", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] } ] }, { "uniprot_ac": "G3HCC1", "gene_name": "Chek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] } ] }, { "uniprot_ac": "G3HDE8", "gene_name": "Pck2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] } ] }, { "uniprot_ac": "G3HEH4", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] } ] }, { "uniprot_ac": "G3HER3", "gene_name": "Tssk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] } ] }, { "uniprot_ac": "G3HLS6", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] } ] }, { "uniprot_ac": "G3HMY1", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] } ] }, { "uniprot_ac": "G3HT38", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] } ] }, { "uniprot_ac": "G3HTW4", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] } ] }, { "uniprot_ac": "G3HV08", "gene_name": "Cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] } ] }, { "uniprot_ac": "G3HVB0", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] } ] }, { "uniprot_ac": "G3HVN3", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] } ] }, { "uniprot_ac": "G3HX91", "gene_name": "Prkd3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] } ] }, { "uniprot_ac": "G3HXQ8", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] } ] }, { "uniprot_ac": "G3HY42", "gene_name": "Akt3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] } ] }, { "uniprot_ac": "G3HZ18", "gene_name": "LOC100756665", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] } ] }, { "uniprot_ac": "G3HZH7", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] } ] }, { "uniprot_ac": "G3HZU1", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] } ] }, { "uniprot_ac": "G3I0W5", "gene_name": "Stk38l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] } ] }, { "uniprot_ac": "G3I3E2", "gene_name": "Pdik1l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] } ] }, { "uniprot_ac": "G3I3Z8", "gene_name": "Rps6kb2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] } ] }, { "uniprot_ac": "G3I472", "gene_name": "LOC100760228", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] } ] }, { "uniprot_ac": "G3I5H0", "gene_name": "Cilk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] } ] }, { "uniprot_ac": "G3I724", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] } ] }, { "uniprot_ac": "G3I7I8", "gene_name": "Chek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] } ] }, { "uniprot_ac": "G3I8T5", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] } ] }, { "uniprot_ac": "G3IB29", "gene_name": "Irak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] } ] }, { "uniprot_ac": "G3ICC3", "gene_name": "Cdk20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] } ] }, { "uniprot_ac": "G3IDN3", "gene_name": "Map3k11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] } ] }, { "uniprot_ac": "G3IFB6", "gene_name": "Pkmyt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] } ] }, { "uniprot_ac": "G3IGI9", "gene_name": "Slk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] } ] }, { "uniprot_ac": "G3IKJ7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] } ] }, { "uniprot_ac": "G3IN30", "gene_name": "Plk1", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IN30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IN30" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "G3IN30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IN30" } ] } ] }, { "uniprot_ac": "O55076", "gene_name": "CDK2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "O55076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O55076" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "O55076", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O55076" } ] } ] }, { "uniprot_ac": "P25321", "gene_name": "PRKACA", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "P25321", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25321" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "P25321", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P25321" } ] } ] }, { "uniprot_ac": "P50310", "gene_name": "PGK1", "activity": [ { "ec_number": "2.7.2.3", "activity": "(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP.", "evidence": [ { "id": "P50310", "database": 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{ "id": "A0A9J7KB98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB98" }, { "id": "PS51092", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51092" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-II", "eco_id": "ECO_0000259", "start_pos": 51, "end_pos": 95, "start_aa": "Ile", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 83, "end_pos": 85 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7KBA2-1", "uniprot_ac": "A0A9J7KBA2", "uniprot_id": "A0A9J7KBA2_CRIGR", "mass": { "chemical_mass": 258959.0, "monoisotopic_mass": 258959.0 }, "refseq": { "ac": "XP_035305096", "name": "LOW QUALITY PROTEIN: protein capicua homolog isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305096" }, "gene_names": [ { "name": "Cic", "type": "recommended", "evidence": [ { "id": "A0A9J7KBA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBA2" } ] }, { "name": "Cic", "type": "synonym", "evidence": [ { "id": "XP_035305096", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305096" } ] } ], "protein_names": [ { "name": "Protein capicua homolog", "type": "recommended", "evidence": [ { "id": "A0A9J7KBA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBA2/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: protein capicua homolog isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035305096", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305096" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305096", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305096" } ] }, { "annotation": "Transcriptional repressor which plays a role in development of the central nervous system (CNS). In concert with ATXN1 and ATXN1L, involved in brain development.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KBA2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBA2#function" }, { "database": "UniProtKB", "id": "ARBA00053962", "url": "https://www.uniprot.org/uniprotkb/ARBA00053962#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KBA2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBA2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cic", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBA2", "locus": {} } ], "crossref": [ { "id": "cd21990", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21990", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100756465", "url": "https://www.ncbi.nlm.nih.gov/gene/100756465", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032147", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032147", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058606", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058606", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058607", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058607", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756465", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756465", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KBA2", "url": "https://www.orthodb.org/?gene=A0A9J7KBA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13059", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13059", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13059:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13059:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00505", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00505", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25981", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25981", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305096", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305096", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KBA2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBA2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKPMKKVCPGLAGSASGSKSPPATRAKALRRRGAGEGDKPEEEDEEAQPQEQTGPEEADEGEEEEAERDPGAEGPPPELQPNDPTPGLAEDPKGDGEAGRWEPSLSRKTATFKSRAPKKKYVEEHGAGSGGVGGAPEEHERTPEDASALGVPPRPPTSTRSSSTDTASEHSADLEDEPAEACGPGPWPSSTTSGGYDLRQLRSQRVLARRRDGLFLPAVVRQVRRSQDLGVQFPGDRALTFYDGMSGGGVDVVLDATPPPGALMVGTAVCTCVEPGMAAYREGVVVEVATKPAAYKVRLSPGPSSHPGPPGPLPQAQQPLHREPEEAVWVTRSSLRLLRRPWDPEALLRKHPAGPEEEQAEPGVTLPPCPSSLEPKQPEDAEVSNISFGSNLGTHCEEGEEKHPPALGTPVLLPLPPPQLLSPPPKSPAFAGPGRPGEQPSPCQEGSQGGSRSSSVASLEKGAAPAARARTPLTAAQQKYKKGDVVCTPNGIRKKFNGKQWRRLCSRDGCMKESQRRGYCSRHLSMRTKEMEGLADGGPGGTGRPAGVAAREGSTEFDWGDETSRDSEASSVAARGDSRPRLVAPADLSRFEFDECEAAVMLVSLGSSRSGTPSFSPVSTQSPFSPAPSPSPSPLFGFRPANFSPINASPVIQRTAVRSRHLSASTPKAGVLTPPDLGPHPPPPAPRERHSSGILPTFQTNLTFTVPISPGRRKTELLPHPGTLGASGAGGGGAAPDFPKGDSLDSGVDSVSHTPTPSTPAGFRAVSPAVPFSRSRQPSPLLLLSPPAGLTSDPGPSVRRVPAVQRDSPVIVRNPDVPLPSKFPGEASEARAGGPGRGCRETAVPPGVASGKPGLPPPLPAPVPITVPPAAPTAVAQPMPTLGLASSPFQPVAFHPSPAALLPVLVPSSYPSHPAPKKEVIMGRPGTVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHEQPPGGAGSADPGRPPGATCPESPGPGPPLTVGSVDPGKSLPPTTEEEAPGPPGESRLDSETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPASLGLAGGHKETRERSMSETGTAAAPGVSSELLSVAAQTLLSSDTKPPGSGPCGAERLHTVGGPGSARPRAFSHSGVHSLDGGEVDSQALQELTQMVSGPTSYSGPKPSSQYGAPGSFAAPGEGGTLATSGRPPLLPSRASRSQRAASEDMTSDEERMVICEEEGDDDVIADDSFGTTDIDLKCKERVTDSESGDSSGEDPEGNKGFGRKVFSPVIRSSFTHCRPTLDPEPPGPPDPPAAFGKGYGPTPSSSSPASTSVSTSFSLGSGTFKTQESGQGSTAVPLRPPPPGAGGPTTPSKATRFLPTDPATFRRKRPESVGSLEAPGPSVIAAPPSAGGNILQTLVLPPSKEEREGSGTRVPSAPAPAPAPAPALAYGAPAAPLSRPAATMVTNVVRPVSSTPVPIASKPFPPSGRAEASSNDTVGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPASSAVQFIAQGAPGSATPAGSGASAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTAGIPILQSVPSAPPPKAQSVSPVQATPSGGSAQLLPGKVLVPLAAPSMSSVRGGGAGQPLPLVSSPFSVPVQNGAQQPSKIIQLTPVPVSTPSGLVPPLSPATMPGPTSQPQKVLLPSSTRITYVQSAGGHTLPLGTSPACSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACTAPGGPVITAFYPGSPAPTSAPLGPPSQAPPSLVYTVATSTTPPAATILPKGPPASATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFESGTTGRPGPTPRQSLDSGAAREPAAPESELEGQPPPPVPPPPPETWPAARSSPPPPLPAEERPGTKGPETASKFPSSSSDWRVPGLGLESRGEPPAPPSPAPAPATVPSGSNSGSGSGSSEGSSGRAAGDTPERKEVTGSVKKMKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTETEDVLGELEYEKVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPGPPPTGMAATPVPTPSPAGGPDPTSPGSDSGTAQTAPPLPPPPEPGPGQPGWEGAPQPSPPPSGPSTAATGR", "length": 2521, "header": "tr|A0A9J7KBA2-1|A0A9J7KBA2_CRIGR Isoform 1 of Protein capicua homolog OS=Cricetulus griseus OX=10029 GN=Cic PE=4 SV=1 CANONICAL=A0A9J7KBA2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KBA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBA2/entry#A0A9J7KBA2-1", "sequence": { "sequence": "MKPMKKVCPGLAGSASGSKSPPATRAKALRRRGAGEGDKPEEEDEEAQPQEQTGPEEADEGEEEEAERDPGAEGPPPELQPNDPTPGLAEDPKGDGEAGRWEPSLSRKTATFKSRAPKKKYVEEHGAGSGGVGGAPEEHERTPEDASALGVPPRPPTSTRSSSTDTASEHSADLEDEPAEACGPGPWPSSTTSGGYDLRQLRSQRVLARRRDGLFLPAVVRQVRRSQDLGVQFPGDRALTFYDGMSGGGVDVVLDATPPPGALMVGTAVCTCVEPGMAAYREGVVVEVATKPAAYKVRLSPGPSSHPGPPGPLPQAQQPLHREPEEAVWVTRSSLRLLRRPWDPEALLRKHPAGPEEEQAEPGVTLPPCPSSLEPKQPEDAEVSNISFGSNLGTHCEEGEEKHPPALGTPVLLPLPPPQLLSPPPKSPAFAGPGRPGEQPSPCQEGSQGGSRSSSVASLEKGAAPAARARTPLTAAQQKYKKGDVVCTPNGIRKKFNGKQWRRLCSRDGCMKESQRRGYCSRHLSMRTKEMEGLADGGPGGTGRPAGVAAREGSTEFDWGDETSRDSEASSVAARGDSRPRLVAPADLSRFEFDECEAAVMLVSLGSSRSGTPSFSPVSTQSPFSPAPSPSPSPLFGFRPANFSPINASPVIQRTAVRSRHLSASTPKAGVLTPPDLGPHPPPPAPRERHSSGILPTFQTNLTFTVPISPGRRKTELLPHPGTLGASGAGGGGAAPDFPKGDSLDSGVDSVSHTPTPSTPAGFRAVSPAVPFSRSRQPSPLLLLSPPAGLTSDPGPSVRRVPAVQRDSPVIVRNPDVPLPSKFPGEASEARAGGPGRGCRETAVPPGVASGKPGLPPPLPAPVPITVPPAAPTAVAQPMPTLGLASSPFQPVAFHPSPAALLPVLVPSSYPSHPAPKKEVIMGRPGTVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHEQPPGGAGSADPGRPPGATCPESPGPGPPLTVGSVDPGKSLPPTTEEEAPGPPGESRLDSETESDHDDAFLSIMSPEIQLPLPPGKRRTQSLSALPKERDSSSEKDGRSPNKREKDHIRRPMNAFMIFSKRHRALVHQRHPNQDNRTVSKILGEWWYALGPKEKQKYHDLAFQVKEAHFKAHPDWKWCNKDRKKSSSEAKPASLGLAGGHKETRERSMSETGTAAAPGVSSELLSVAAQTLLSSDTKPPGSGPCGAERLHTVGGPGSARPRAFSHSGVHSLDGGEVDSQALQELTQMVSGPTSYSGPKPSSQYGAPGSFAAPGEGGTLATSGRPPLLPSRASRSQRAASEDMTSDEERMVICEEEGDDDVIADDSFGTTDIDLKCKERVTDSESGDSSGEDPEGNKGFGRKVFSPVIRSSFTHCRPTLDPEPPGPPDPPAAFGKGYGPTPSSSSPASTSVSTSFSLGSGTFKTQESGQGSTAVPLRPPPPGAGGPTTPSKATRFLPTDPATFRRKRPESVGSLEAPGPSVIAAPPSAGGNILQTLVLPPSKEEREGSGTRVPSAPAPAPAPAPALAYGAPAAPLSRPAATMVTNVVRPVSSTPVPIASKPFPPSGRAEASSNDTVGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPASSAVQFIAQGAPGSATPAGSGASAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTAGIPILQSVPSAPPPKAQSVSPVQATPSGGSAQLLPGKVLVPLAAPSMSSVRGGGAGQPLPLVSSPFSVPVQNGAQQPSKIIQLTPVPVSTPSGLVPPLSPATMPGPTSQPQKVLLPSSTRITYVQSAGGHTLPLGTSPACSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACTAPGGPVITAFYPGSPAPTSAPLGPPSQAPPSLVYTVATSTTPPAATILPKGPPASATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFESGTTGRPGPTPRQSLDSGAAREPAAPESELEGQPPPPVPPPPPETWPAARSSPPPPLPAEERPGTKGPETASKFPSSSSDWRVPGLGLESRGEPPAPPSPAPAPATVPSGSNSGSGSGSSEGSSGRAAGDTPERKEVTGSVKKMKVRPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTETEDVLGELEYEKVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPGPPPTGMAATPVPTPSPAGGPDPTSPGSDSGTAQTAPPLPPPPEPGPGQPGWEGAPQPSPPPSGPSTAATGR", 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May have some role in extracellular matrix engulfment or growth factor receptor recycling, both of which can modulate cell survival.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KBD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBD4#function" }, { "database": "UniProtKB", "id": "ARBA00045144", "url": "https://www.uniprot.org/uniprotkb/ARBA00045144#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KBD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBD4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tmem150b", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBD4", "locus": {} } ], "crossref": [ { "id": "A0A9J7KBD4", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7KBD4", "database": "AlphaFoldDB", "categories": [] }, { "id": "100772661", "url": "https://www.ncbi.nlm.nih.gov/gene/100772661", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772661", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772661", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KBD4", "url": "https://www.orthodb.org/?gene=A0A9J7KBD4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21324", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21324", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21324:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21324:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10277", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10277", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305187", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305187", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KBD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBD4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWSYLSLLPVILALWAIAGIWLVFAIAVANRSVDLKKGFPFISNCGSYAPQSCIFGQILNTGAALAIWICIVRYHQLRDWGVKKWQNQLILWAGLLCALGTSIVGNFQEKNQKGAHMAGAFLAFILGNLYFWLQFLLSWIKGLPQPGPRWVKLLRLSFCVISTILIVAMIVLYSQRMRSASAACEWAVAMVLFLLFGLFAVDFSRLRGCTLHLQPNLDASLPQATFGSPHIQASQAL", "length": 237, "header": "tr|A0A9J7KBD4-1|A0A9J7KBD4_CRIGR Isoform 1 of Modulator of macroautophagy TMEM150B isoform X2 OS=Cricetulus griseus OX=10029 GN=Tmem150b PE=3 SV=1 CANONICAL=A0A9J7KBD4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KBD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBD4/entry#A0A9J7KBD4-1", "sequence": { "sequence": "MWSYLSLLPVILALWAIAGIWLVFAIAVANRSVDLKKGFPFISNCGSYAPQSCIFGQILNTGAALAIWICIVRYHQLRDWGVKKWQNQLILWAGLLCALGTSIVGNFQEKNQKGAHMAGAFLAFILGNLYFWLQFLLSWIKGLPQPGPRWVKLLRLSFCVISTILIVAMIVLYSQRMRSASAACEWAVAMVLFLLFGLFAVDFSRLRGCTLHLQPNLDASLPQATFGSPHIQASQAL", "length": 237, "header": "tr|A0A9J7KBD4-1|A0A9J7KBD4_CRIGR Isoform 1 of Modulator of macroautophagy TMEM150B isoform X2 OS=Cricetulus griseus OX=10029 GN=Tmem150b PE=3 SV=1 CANONICAL=A0A9J7KBD4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KBD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBD4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KBD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBD4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100772661", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772661", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "autophagosome membrane", "id": "GO:0000421", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000421", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KBD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBD4" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KBD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBD4" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KBD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBD4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KBD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBD4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 30, "end_pos": 32, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7KBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBD4" }, { "id": "PF10277", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10277" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CWH43-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 5, "end_pos": 204, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 30, "end_pos": 32 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7KBE8-1", "uniprot_ac": "A0A9J7KBE8", "uniprot_id": "A0A9J7KBE8_CRIGR", "mass": { "chemical_mass": 78670.0, "monoisotopic_mass": 78670.0 }, "refseq": { "ac": "XP_035305240", "name": "carcinoembryonic antigen-related cell adhesion molecule 3-like isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305240" }, "gene_names": [ { "name": "LOC107976976", "type": "recommended", "evidence": [ { "id": "A0A9J7KBE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBE8" } ] }, { "name": "LOC107976976", "type": "synonym", "evidence": [ { "id": "XP_035305240", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305240" } ] } ], "protein_names": [ { "name": "Carcinoembryonic antigen-related cell adhesion molecule 3-like isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7KBE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBE8/entry#names_and_taxonomy" } ] }, { "name": "carcinoembryonic antigen-related cell adhesion molecule 3-like isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035305240", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305240" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305240", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305240" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KBE8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBE8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC107976976", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBE8", "locus": {} } ], "crossref": [ { "id": "A0A9J7KBE8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7KBE8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05740", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05740", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05774", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05774", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "107976976", "url": "https://www.ncbi.nlm.nih.gov/gene/107976976", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050831", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050831", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:107976976", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:107976976", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KBE8", "url": "https://www.orthodb.org/?gene=A0A9J7KBE8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44427", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44427", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44427:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44427:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305240", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305240", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KBE8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBE8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEMPSVLLCNGCTPWQGLLLTASLLACWHFHTTSASVNIESVPPHVVEGENVLLLVHNLPENLSTLVWSKGENIRDNAIGLYTLSQDVSAPGPLHSGRETVYHNGSLLLRNVTRKDTGFYTLQSLNSHEDIASRTTIYLHVHTSNCGCPSTCAQITIESVPSSIVEGESVLLVVYNLPENLRAFFWYKGGIVSKNIEVAWHQIARNTTGFGPAYSGREIVYSNGSLLLQNVTWNDTGFYTLRTLSRDLETELVRVQLQLDSCVCKYKNPTTNAQPTVESVPPSVAEGGNALLVVPNLPKDTRAIFWYKGAVAFKNQEVARRKIAAKSSVLGPAHSGRETMYSNGSLLLQNVTRNDAGFYTLRTVTTDLKVGLVHVKLLVDTSLSVCCNSLTSVQLMIEPVPQNAVKGDSVLFLVHNLPEDLRAFAWYKLGHNNQKFKIAEFSRVTNYITHGPAYSERAVVYTNGSLLLQDVMQTDAGVYVLQTLNRDFKTEKAYVQLHVYTCRLPPPNGQLSIELMPTNVAEGKNALLLAHNMPENLVAFHWYLEVAILNSRLIAQKDTIDNKIWIAAAYSGRVTVYHNGSLLFHNATQDDTGFYSLVTISTRVKTQQTHVDLRIYKPVTQPFIQVTSTTVTAQSSVVFTCLSGDTGVSICWIFNNRNLQLTERMTLSPTKCQLSIDPVRREDAGDYQCEVFNPVSSRISLPVSLAVTNE", "length": 710, "header": "tr|A0A9J7KBE8-1|A0A9J7KBE8_CRIGR Isoform 1 of Carcinoembryonic antigen-related cell adhesion molecule 3-like isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC107976976 PE=3 SV=1 CANONICAL=A0A9J7KBE8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KBE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBE8/entry#A0A9J7KBE8-1", "sequence": { "sequence": "MEMPSVLLCNGCTPWQGLLLTASLLACWHFHTTSASVNIESVPPHVVEGENVLLLVHNLPENLSTLVWSKGENIRDNAIGLYTLSQDVSAPGPLHSGRETVYHNGSLLLRNVTRKDTGFYTLQSLNSHEDIASRTTIYLHVHTSNCGCPSTCAQITIESVPSSIVEGESVLLVVYNLPENLRAFFWYKGGIVSKNIEVAWHQIARNTTGFGPAYSGREIVYSNGSLLLQNVTWNDTGFYTLRTLSRDLETELVRVQLQLDSCVCKYKNPTTNAQPTVESVPPSVAEGGNALLVVPNLPKDTRAIFWYKGAVAFKNQEVARRKIAAKSSVLGPAHSGRETMYSNGSLLLQNVTRNDAGFYTLRTVTTDLKVGLVHVKLLVDTSLSVCCNSLTSVQLMIEPVPQNAVKGDSVLFLVHNLPEDLRAFAWYKLGHNNQKFKIAEFSRVTNYITHGPAYSERAVVYTNGSLLLQDVMQTDAGVYVLQTLNRDFKTEKAYVQLHVYTCRLPPPNGQLSIELMPTNVAEGKNALLLAHNMPENLVAFHWYLEVAILNSRLIAQKDTIDNKIWIAAAYSGRVTVYHNGSLLFHNATQDDTGFYSLVTISTRVKTQQTHVDLRIYKPVTQPFIQVTSTTVTAQSSVVFTCLSGDTGVSICWIFNNRNLQLTERMTLSPTKCQLSIDPVRREDAGDYQCEVFNPVSSRISLPVSLAVTNE", "length": 710, "header": "tr|A0A9J7KBE8-1|A0A9J7KBE8_CRIGR Isoform 1 of Carcinoembryonic antigen-related cell adhesion molecule 3-like isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC107976976 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Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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LOC100768301 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7KBS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBS7/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC100768301 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035305620", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305620" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 43% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305620", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305620" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KBS7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBS7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100768301", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBS7", "locus": {} } ], "crossref": [ { "id": "A0A9J7KBS7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7KBS7", "database": "AlphaFoldDB", "categories": [] }, { "id": "100768301", "url": "https://www.ncbi.nlm.nih.gov/gene/100768301", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051487", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051487", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768301", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768301", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KBS7", "url": "https://www.orthodb.org/?gene=A0A9J7KBS7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24256", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24256", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305620", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305620", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KBS7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBS7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAARVCRPSASSLVPPHAGICGRLDKMAAGLADSLPPRAAVRHEASPQLGQQRLLSRRDAQKLTRFIKYQIDAILEKPVLVHYHRLAALDSELPDDNNPPPSPNPVLPDRGIKTLPKPAQTPAQSSTPKLTPITPSISPDPGTVDRLFNLLWPQIKYYSGEILVSQAQRRVMREPVSMTIALMLGIGGLVAVSVLQIPRPSLGSSPLIGNLPPADSYIDVPWLVSMPGNCQGIVLTPWLILSTANCLKKSKMSHLDISGVNDPESIPRGQRICLYPKFDPQDENDPVKADIGLVILEEPLYGEEIPISQSSNISLKSCSKCQYRSCEVYEYQSSRKLGTTTVKKIAVQLLDFSTCYHQHSYLEKTEGLCIQSQPREDCWIQRASPVLCLLKNHWELVGLIHKTSRICQNPTVIIRTAPYFSWMKRFIKWILLNRLLIKSWQI", "length": 443, "header": "tr|A0A9J7KBS7-1|A0A9J7KBS7_CRIGR Isoform 1 of Uncharacterized protein LOC100768301 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100768301 PE=3 SV=1 CANONICAL=A0A9J7KBS7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KBS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBS7/entry#A0A9J7KBS7-1", "sequence": { "sequence": "MAAARVCRPSASSLVPPHAGICGRLDKMAAGLADSLPPRAAVRHEASPQLGQQRLLSRRDAQKLTRFIKYQIDAILEKPVLVHYHRLAALDSELPDDNNPPPSPNPVLPDRGIKTLPKPAQTPAQSSTPKLTPITPSISPDPGTVDRLFNLLWPQIKYYSGEILVSQAQRRVMREPVSMTIALMLGIGGLVAVSVLQIPRPSLGSSPLIGNLPPADSYIDVPWLVSMPGNCQGIVLTPWLILSTANCLKKSKMSHLDISGVNDPESIPRGQRICLYPKFDPQDENDPVKADIGLVILEEPLYGEEIPISQSSNISLKSCSKCQYRSCEVYEYQSSRKLGTTTVKKIAVQLLDFSTCYHQHSYLEKTEGLCIQSQPREDCWIQRASPVLCLLKNHWELVGLIHKTSRICQNPTVIIRTAPYFSWMKRFIKWILLNRLLIKSWQI", "length": 443, "header": "tr|A0A9J7KBS7-1|A0A9J7KBS7_CRIGR Isoform 1 of Uncharacterized protein LOC100768301 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100768301 PE=3 SV=1 CANONICAL=A0A9J7KBS7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 135, "start_aa": "Thr", "end_pos": 135, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr135", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KBS7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBS7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KBS7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBS7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7KBS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBS7" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 208, "end_pos": 429, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], 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{ "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 15% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035308308", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308308" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KBV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBV1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113832237", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBV1", "locus": {} } ], "crossref": [ { "id": "A0A9J7KBV1", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7KBV1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14126", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14126", "database": "CDD", "categories": [ "Protein 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"OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11909", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11909", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12605", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12605", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035308308", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308308", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "17989", "url": "https://www.rhea-db.org/rhea/17989", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "46608", "url": "https://www.rhea-db.org/rhea/46608", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KBV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBV1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDHSNREKDDRQQTTQTMAQRNTHCSRPSGTSASSGGLMVGPNFSVGKKIGCGKFGELRLGKNLYTNEYVAIKVEQIKSRGPPLHLEYRFYEQLGSAGEGIPQVYYFGTCGKYNAMVLELLGPSLQDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYGEHKSLTGTARYVSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQELKADTLKERRQKIGDSKRNTPIEVLCENFPEETATYLRYVRRLDFFEKPDYEYLRTLFTDMLERKGYTFDYAYDWVGRPFPTPVGSVHVDSGASVITRESHTHRDLPSQQKQPLRNHPASSERRGEWEIHPSRQTNTSFLMSHLAADCHGGSVQGRNCQQDKEFEIEANIIASPLEEDILENDFRILKSLDCGSFGEVKLACHLPTNTEVAIKVVEKNHKPSADHISEAEILQSLEHRNTVRFFHVMDTLKLTYVVMEYVAGKDLAMILNGKAYLKEDEGGPIFLQVVSAVHFLHKRHIAYCGIKLENILVDRAGDIKLCDFGMAIQLKERKMLMKVCGTLLYMAPEILARKTL", "length": 607, "header": "tr|A0A9J7KBV1-1|A0A9J7KBV1_CRIGR Isoform 1 of LOW QUALITY PROTEIN: casein kinase I-like OS=Cricetulus griseus OX=10029 GN=LOC113832237 PE=4 SV=1 CANONICAL=A0A9J7KBV1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KBV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBV1/entry#A0A9J7KBV1-1", "sequence": { "sequence": "MDHSNREKDDRQQTTQTMAQRNTHCSRPSGTSASSGGLMVGPNFSVGKKIGCGKFGELRLGKNLYTNEYVAIKVEQIKSRGPPLHLEYRFYEQLGSAGEGIPQVYYFGTCGKYNAMVLELLGPSLQDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYGEHKSLTGTARYVSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQELKADTLKERRQKIGDSKRNTPIEVLCENFPEETATYLRYVRRLDFFEKPDYEYLRTLFTDMLERKGYTFDYAYDWVGRPFPTPVGSVHVDSGASVITRESHTHRDLPSQQKQPLRNHPASSERRGEWEIHPSRQTNTSFLMSHLAADCHGGSVQGRNCQQDKEFEIEANIIASPLEEDILENDFRILKSLDCGSFGEVKLACHLPTNTEVAIKVVEKNHKPSADHISEAEILQSLEHRNTVRFFHVMDTLKLTYVVMEYVAGKDLAMILNGKAYLKEDEGGPIFLQVVSAVHFLHKRHIAYCGIKLENILVDRAGDIKLCDFGMAIQLKERKMLMKVCGTLLYMAPEILARKTL", "length": 607, "header": "tr|A0A9J7KBV1-1|A0A9J7KBV1_CRIGR Isoform 1 of LOW QUALITY PROTEIN: casein kinase I-like OS=Cricetulus griseus OX=10029 GN=LOC113832237 PE=4 SV=1 CANONICAL=A0A9J7KBV1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 335, "start_aa": "Thr", "end_pos": 335, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr335", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KBV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBV1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KBV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBV1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:113832237", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113832237", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KBV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBV1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KBV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBV1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KBV1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBV1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRI0-1", "G3GWJ3-1", "G3GYQ3-1", "A0A9J7GY39-1", "G3H3C3-1", "G3HAZ9-1", "G3HLS6-1", "G3HVB0-1", "G3HVN3-1", "G3I7I8-1", 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{ "uniprot_ac": "A0A061HUS7", "gene_name": "Srpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] } ] }, { "uniprot_ac": "A0A061HVM6", "gene_name": "Hipk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] } ] }, { "uniprot_ac": "A0A061HZ27", "gene_name": "Pik3cg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] } ] }, { "uniprot_ac": "A0A061I033", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] } ] }, { "uniprot_ac": "A0A061I8L6", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] } ] }, { "uniprot_ac": "A0A061I9F9", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] } ] }, { "uniprot_ac": "A0A061IJA8", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] } ] }, { "uniprot_ac": "A0A061IJW6", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] } ] }, { "uniprot_ac": "A0A061ILI7", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] } ] }, { "uniprot_ac": "A0A3L7GMP6", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] } ] }, { "uniprot_ac": "A0A3L7GPC7", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] } ] }, { "uniprot_ac": "A0A3L7HK04", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] } ] }, { "uniprot_ac": "A0A3L7HKC4", "gene_name": "Cdkl4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] } ] }, { "uniprot_ac": "A0A3L7HMX8", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] } ] }, { "uniprot_ac": "A0A3L7HQF4", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] } ] }, { "uniprot_ac": "A0A3L7HRZ8", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] } ] }, { "uniprot_ac": "A0A3L7HV37", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] } ] }, { "uniprot_ac": "A0A3L7I1E7", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0A3L7I1E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1E7" } ] } ] }, { "uniprot_ac": "A0A3L7I1R2", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] } ] }, { "uniprot_ac": "A0A3L7I4E3", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] } ] }, { "uniprot_ac": "A0A3L7I5Y4", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] } ] }, { "uniprot_ac": "A0A3L7I870", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] } ] }, { "uniprot_ac": "A0A3L7IB60", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] } ] }, { "uniprot_ac": "A0A3L7IBX6", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] } ] }, { "uniprot_ac": "A0A3L7ID00", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] } ] }, { "uniprot_ac": "A0A3L7IEL5", "gene_name": "LOC113833388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] } ] }, { "uniprot_ac": "A0A3L7IER1", "gene_name": "Stk38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] } ] }, { "uniprot_ac": "A0A8C2L7R1", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] } ] }, { "uniprot_ac": "A0A8C2LA64", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] } ] }, { "uniprot_ac": "A0A8C2LC89", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] } ] }, { "uniprot_ac": "A0A8C2LCN7", "gene_name": "Csnk2a2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] } ] }, { "uniprot_ac": "A0A8C2LDE5", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] } ] }, { "uniprot_ac": "A0A8C2LDQ8", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] } ] }, { "uniprot_ac": "A0A8C2LDU9", "gene_name": "Ern1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] } ] }, { "uniprot_ac": "A0A8C2LE67", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] } ] }, { "uniprot_ac": "A0A8C2LEI8", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] } ] }, { "uniprot_ac": "A0A8C2LFT9", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] } ] }, { "uniprot_ac": "A0A8C2LH99", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] } ] }, { "uniprot_ac": "A0A8C2LHE9", "gene_name": "Camk1d", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] } ] }, { "uniprot_ac": "A0A8C2LI14", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] } ] }, { "uniprot_ac": "A0A8C2LI15", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] } ] }, { "uniprot_ac": "A0A8C2LII0", "gene_name": "Cdk6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] } ] }, { "uniprot_ac": "A0A8C2LK72", "gene_name": "Rps6ka4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] } ] }, { "uniprot_ac": "A0A8C2LMC9", "gene_name": "Mknk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] } ] }, { "uniprot_ac": "A0A8C2LMJ0", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] } ] }, { "uniprot_ac": "A0A8C2LPE9", "gene_name": "Mast3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] } ] }, { "uniprot_ac": "A0A8C2LPR4", "gene_name": "Mapkapk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] } ] }, { "uniprot_ac": "A0A8C2LQB2", "gene_name": "Pak5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] } ] }, { "uniprot_ac": "A0A8C2LQS5", "gene_name": "Rps6kb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] } ] }, { "uniprot_ac": "A0A8C2LRT3", "gene_name": "Map3k5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] } ] }, { "uniprot_ac": "A0A8C2LTD1", "gene_name": "Prkcb", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] } ] }, { "uniprot_ac": "A0A8C2LTT6", "gene_name": "Prkd2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] } ] }, { "uniprot_ac": "A0A8C2LTW4", "gene_name": "Dclk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] } ] }, { "uniprot_ac": "A0A8C2LTZ7", "gene_name": "Tssk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] } ] }, { "uniprot_ac": "A0A8C2LVR4", "gene_name": "LOC100775051", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] } ] }, { "uniprot_ac": "A0A8C2LVV5", "gene_name": "Camk1g", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] } ] }, { "uniprot_ac": "A0A8C2LY02", "gene_name": "Mapk11", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] } ] }, { "uniprot_ac": "A0A8C2LY52", "gene_name": "Dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY52", "database": 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"https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] } ] }, { "uniprot_ac": "A0A8C2M165", "gene_name": "Cdk4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] } ] }, { "uniprot_ac": "A0A8C2M187", "gene_name": "Map2k2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] } ] }, { "uniprot_ac": "A0A8C2M1F6", "gene_name": "Cdk19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] } ] }, { "uniprot_ac": "A0A8C2M3Y9", "gene_name": "Aurka", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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[ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] } ] }, { "uniprot_ac": "A0A8C2M6X8", "gene_name": "Prkcq", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] } ] }, { "uniprot_ac": "A0A8C2M7I3", "gene_name": "Camkk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] 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[ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] } ] }, { "uniprot_ac": "A0A8C2MB66", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] } ] }, { "uniprot_ac": "A0A8C2MBI9", "gene_name": "Tnk1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] } ] }, { "uniprot_ac": "A0A8C2MBP2", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] } ] }, { "uniprot_ac": "A0A8C2MBW2", "gene_name": "Tp53rk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] } ] }, { "uniprot_ac": "A0A8C2MC09", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] } ] }, { "uniprot_ac": "A0A8C2MCI5", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] } ] }, { "uniprot_ac": "A0A8C2MCX3", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] } ] }, { "uniprot_ac": "A0A8C2MEU5", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] } ] }, { "uniprot_ac": "A0A8C2MFN1", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] } ] }, { "uniprot_ac": "A0A8C2MH43", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] } ] }, { "uniprot_ac": "A0A8C2MJ02", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] } ] }, { "uniprot_ac": "A0A8C2ML15", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] } ] }, { "uniprot_ac": "A0A8C2MMI4", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] } ] }, { "uniprot_ac": "A0A8C2MMQ4", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] } ] }, { "uniprot_ac": "A0A8C2MMZ5", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] } ] }, { "uniprot_ac": "A0A8C2MP62", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] } ] }, { "uniprot_ac": "A0A8C2MQ42", "gene_name": "Cdkl5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] } ] }, { "uniprot_ac": "A0A8C2MQ73", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] } ] }, { "uniprot_ac": "A0A8C2MQL9", "gene_name": "LOC100766643", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] } ] }, { "uniprot_ac": "A0A8C2MQM0", "gene_name": "Camkk2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] } ] }, { "uniprot_ac": "A0A8C2MQS3", "gene_name": "Taok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] } ] }, { "uniprot_ac": "A0A8C2MR08", "gene_name": "Stk36", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MR08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MR08" } ] } ] }, { "uniprot_ac": "A0A8C2MSQ2", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MSQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSQ2" } ] } ] }, { "uniprot_ac": "A0A8C2MTI7", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTI7" } ] } ] }, { "uniprot_ac": "A0A8C2MUQ5", "gene_name": "Mapkapk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MUQ5" } ] } ] }, { "uniprot_ac": "A0A8C2MV78", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2MV78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MV78" } ] } ] }, { "uniprot_ac": "A0A8C2MYH0", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MYH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MYH0" } ] } ] }, { "uniprot_ac": "A0A8C2N0J6", "gene_name": "Camk4", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0J6" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2N0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N0J6" } ] } ] }, { "uniprot_ac": "A0A8C2N185", "gene_name": "Mak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N185" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N185", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N185" } ] } ] }, { "uniprot_ac": "A0A8C2N210", "gene_name": "Nek10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N210" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N210", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N210" } ] } ] }, { "uniprot_ac": "A0A8C2N310", "gene_name": "Rps6kl1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N310", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N310" } ] } ] }, { "uniprot_ac": "A0A8C2N3C9", "gene_name": "LOC100773612", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3C9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3C9" } ] } ] }, { "uniprot_ac": "A0A8C2N3I1", "gene_name": "Nuak2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N3I1", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QHF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHF9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QHF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHF9" } ] } ] }, { "uniprot_ac": "A0A8C2QHS8", "gene_name": "Ripk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QHS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QHS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHS8" } ] } ] }, { "uniprot_ac": "A0A8C2QI80", "gene_name": "Mapk3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QI80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QI80" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2QI80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QI80" } ] } ] }, { "uniprot_ac": "A0A8C2QIA1", "gene_name": "Prkce", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QIA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QIA1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2QIA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QIA1" } ] } ] }, { "uniprot_ac": "A0A8C2QJ34", "gene_name": "Oxsr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QJ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QJ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJ34" } ] } ] }, { "uniprot_ac": "A0A8C2QJA4", "gene_name": "Pak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJA4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QJA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJA4" } ] } ] }, { "uniprot_ac": "A0A8C2QKP7", "gene_name": "Nlk", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QKP7", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8C2QLT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLT0" } ] } ] }, { "uniprot_ac": "A0A8C2QMB3", "gene_name": "Mapk1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMB3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2QMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMB3" } ] } ] }, { "uniprot_ac": "A0A8C2QND0", "gene_name": "Sgk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QND0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] } ] }, { "uniprot_ac": "A0A9J7EZ53", "gene_name": "Map4k4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] } ] }, { "uniprot_ac": "A0A9J7F0G6", "gene_name": "Camk2b", "activity": [ { "ec_number": "2.7.11.17", "activity": 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ADP + H(+).", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] } ] }, { "uniprot_ac": "A0A9J7F0Y2", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0Y2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0Y2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0Y2" } ] } ] }, { "uniprot_ac": "A0A9J7F1D2", "gene_name": "Tnik", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F1D2", "database": 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"https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] } ] }, { "uniprot_ac": "A0A9J7F383", "gene_name": "LOC113833167", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] } ] }, { "uniprot_ac": "A0A9J7F3R3", "gene_name": "Braf", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] } ] }, { "uniprot_ac": "A0A9J7F4P4", "gene_name": "Tnni3k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] } ] }, { "uniprot_ac": "A0A9J7F5B0", "gene_name": "Plk4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] } ] }, { "uniprot_ac": "A0A9J7F773", "gene_name": "Pklr", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] } ] }, { "uniprot_ac": "A0A9J7F821", "gene_name": "Hipk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] } ] }, { "uniprot_ac": "A0A9J7F842", "gene_name": "Pikfyve", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": 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"activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] } ] }, { "uniprot_ac": "A0A9J7F9C4", "gene_name": "Nek5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] } ] }, { "uniprot_ac": "A0A9J7FBT0", "gene_name": "Speg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] } ] }, { "uniprot_ac": "A0A9J7FC43", "gene_name": "Cdk15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC43", "database": 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"ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] } ] }, { "uniprot_ac": "A0A9J7FEY2", "gene_name": "Csnk1a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] } ] }, { "uniprot_ac": "A0A9J7FF13", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] } ] }, { "uniprot_ac": "A0A9J7FF35", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] } ] }, { "uniprot_ac": "A0A9J7FFS7", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] } ] }, { "uniprot_ac": "A0A9J7FGD3", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] } ] }, { "uniprot_ac": "A0A9J7FGF7", "gene_name": "LOC100751450", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] } ] }, { "uniprot_ac": "A0A9J7FI14", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FKM1", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] } ] }, { "uniprot_ac": "A0A9J7FKM9", "gene_name": "LOC113834545", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] } ] }, { "uniprot_ac": "A0A9J7FLY5", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] } ] }, { "uniprot_ac": "A0A9J7FN24", "gene_name": "Alpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] } ] }, { "uniprot_ac": "A0A9J7FN52", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] } ] }, { "uniprot_ac": "A0A9J7FN68", "gene_name": "Mast1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] } ] }, { "uniprot_ac": "A0A9J7FNF0", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] } ] }, { "uniprot_ac": "A0A9J7FS53", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] } ] }, { "uniprot_ac": "A0A9J7FUL0", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] } ] }, { "uniprot_ac": "A0A9J7FVR6", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] } ] }, { "uniprot_ac": "A0A9J7FYJ6", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FYY3", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] } ] }, { "uniprot_ac": "A0A9J7FZ18", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] } ] }, { "uniprot_ac": "A0A9J7FZA7", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] } ] }, { "uniprot_ac": "A0A9J7FZH7", "gene_name": "LOC113835540", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7FZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZH7" } ] } ] }, { "uniprot_ac": "A0A9J7FZW1", "gene_name": "Mok", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FZW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] } ] }, { "uniprot_ac": "A0A9J7FZY8", "gene_name": "Pik3cb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] } ] }, { "uniprot_ac": "A0A9J7G180", "gene_name": "Dstyk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7G180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G180" } ] } ] }, { "uniprot_ac": "A0A9J7G1D9", "gene_name": "Ulk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1D9" } ] } ] }, { "uniprot_ac": "A0A9J7G1H0", "gene_name": "Map4k5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G1H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1H0" } ] } ] }, { "uniprot_ac": "A0A9J7G270", "gene_name": "LOC100754226", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G270", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G270" } ] } ] }, { "uniprot_ac": "A0A9J7G368", "gene_name": "Stk11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] } ] }, { "uniprot_ac": "A0A9J7G3C1", "gene_name": "Dapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] } ] }, { "uniprot_ac": "A0A9J7G4B8", "gene_name": "Cdk18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] } ] }, { "uniprot_ac": "A0A9J7G5F3", "gene_name": "Plk5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5F3" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5F3" } ] } ] }, { "uniprot_ac": "A0A9J7G5N9", "gene_name": "Stk35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] } ] }, { "uniprot_ac": "A0A9J7G6S5", "gene_name": "Trpm7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] } ] }, { "uniprot_ac": "A0A9J7G8N0", "gene_name": "LOC100770044", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G8N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N0" } ] } ] }, { "uniprot_ac": "A0A9J7G8N4", "gene_name": "Sgk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G8N4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G8N4" } ] } ] }, { "uniprot_ac": "A0A9J7G969", "gene_name": "LOC100754771", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G969", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G969" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G969", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G969" } ] } ] }, { "uniprot_ac": "A0A9J7G9D1", "gene_name": "Hipk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G9D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G9D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G9D1" } ] } ] }, { "uniprot_ac": "A0A9J7GAB0", "gene_name": "Pkn3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GAB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB0" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GAB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB0" } ] } ] }, { "uniprot_ac": "A0A9J7GAF4", "gene_name": "Stk10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ] } ] }, { "uniprot_ac": "A0A9J7GBF4", "gene_name": "Csnk1d", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ] } ] }, { "uniprot_ac": "A0A9J7GBI2", "gene_name": "LOC100771767", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBI2" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GBI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBI2" } ] } ] }, { "uniprot_ac": "A0A9J7GBL6", "gene_name": "Ttbk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GBL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBL6" } ] } ] }, { "uniprot_ac": "A0A9J7GD76", "gene_name": "Taok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GD76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GD76" } ] } ] }, { "uniprot_ac": "A0A9J7GES8", "gene_name": "Tlk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GES8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GES8" } ] } ] }, { "uniprot_ac": "A0A9J7GF22", "gene_name": "Aatk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] } ] }, { "uniprot_ac": "A0A9J7GF26", "gene_name": "LOC100752478", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF26" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF26" } ] } ] }, { "uniprot_ac": "A0A9J7GF59", "gene_name": "LOC103160391", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] } ] }, { "uniprot_ac": "A0A9J7GFS3", "gene_name": "Aak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] } ] }, { "uniprot_ac": "A0A9J7GG74", "gene_name": "Cdkl3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] } ] }, { "uniprot_ac": "A0A9J7GGP1", "gene_name": "Map4k1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] } ] }, { "uniprot_ac": "A0A9J7GHB3", "gene_name": "Map2k4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] } ] }, { "uniprot_ac": "A0A9J7GHK2", "gene_name": "LOC100753695", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] } ] }, { "uniprot_ac": "A0A9J7GHV2", "gene_name": "LOC100773845", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] } ] }, { "uniprot_ac": "A0A9J7GI33", "gene_name": "Map3k10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] } ] }, { "uniprot_ac": "A0A9J7GIC4", "gene_name": "Stk26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] } ] }, { "uniprot_ac": "A0A9J7GIM1", "gene_name": "Cdk16", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIM1" } ] } ] }, { "uniprot_ac": "A0A9J7GIN7", "gene_name": "Eif2ak3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLT3" } ] } ] }, { "uniprot_ac": "A0A9J7GMF3", "gene_name": "LOC103158537", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMF3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMF3" } ] } ] }, { "uniprot_ac": "A0A9J7GMK5", "gene_name": "Sbk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { 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} ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H0E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0E7" } ] } ] }, { "uniprot_ac": "A0A9J7H0W8", "gene_name": "Dapk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H0W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0W8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H0W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0W8" } ] } ] }, { "uniprot_ac": "A0A9J7H1I4", "gene_name": "LOC100764243", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H1I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", 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{ "id": "A0A9J7H8E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8E3" } ] } ] }, { "uniprot_ac": "A0A9J7H8L4", "gene_name": "Irak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H8L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8L4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H8L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8L4" } ] } ] }, { "uniprot_ac": "A0A9J7H8U3", "gene_name": "Wnk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H8U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H8U3", "database": "UniProtKB", "url": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7J728", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J728" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7J728", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J728" } ] } ] }, { "uniprot_ac": "A0A9J7JA07", "gene_name": "LOC100750629", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JA07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JA07" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JA07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JA07" } ] } ] }, { "uniprot_ac": "A0A9J7JAB2", "gene_name": "Stk24", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { 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"uniprot_ac": "A0A9J7JJV6", "gene_name": "Mark1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] } ] }, { "uniprot_ac": "A0A9J7JKJ1", "gene_name": "Sik2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] } ] }, { "uniprot_ac": "A0A9J7JLH7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] } ] }, { "uniprot_ac": "A0A9J7JNT2", "gene_name": "LOC113835854", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] } ] }, { "uniprot_ac": "A0A9J7JNU2", "gene_name": "Tnk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] } ] }, { "uniprot_ac": "A0A9J7JPD7", "gene_name": "Lmtk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] } ] }, { "uniprot_ac": "A0A9J7JPE2", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] } ] }, { "uniprot_ac": "A0A9J7JPF2", "gene_name": "LOC100765388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] } ] }, { "uniprot_ac": "A0A9J7JPI2", "gene_name": "Ksr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] } ] }, { "uniprot_ac": "A0A9J7JPY1", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] } ] }, { "uniprot_ac": "A0A9J7JQD1", "gene_name": "Ulk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] } ] }, { "uniprot_ac": "A0A9J7JQV6", "gene_name": "Pkm", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQV6" } ] } ] }, { "uniprot_ac": "A0A9J7JQZ1", "gene_name": "Wnk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQZ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JQZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQZ1" } ] } ] }, { "uniprot_ac": "A0A9J7JRI3", "gene_name": "Cdc42bpb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] } ] }, { "uniprot_ac": "A0A9J7JRJ8", "gene_name": "Mark3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] } ] }, { "uniprot_ac": "A0A9J7JSB5", "gene_name": "LOC113836186", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] } ] }, { "uniprot_ac": "A0A9J7JTJ0", "gene_name": "LOC113838440", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] } ] }, { "uniprot_ac": "A0A9J7JTL3", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] } ] }, { "uniprot_ac": "A0A9J7JU24", "gene_name": "Camk2a", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] } ] }, { "uniprot_ac": "A0A9J7JXM2", "gene_name": "Dcaf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] } ] }, { "uniprot_ac": "A0A9J7JXX3", "gene_name": "Map3k3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] } ] }, { "uniprot_ac": "A0A9J7JYC5", "gene_name": "Nme7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] } ] }, { "uniprot_ac": "A0A9J7JYU7", "gene_name": "Mink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] } ] }, { "uniprot_ac": "A0A9J7JZS0", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] } ] }, { "uniprot_ac": "A0A9J7K1H4", "gene_name": "LOC113837295", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] } ] }, { "uniprot_ac": "A0A9J7K2Q7", "gene_name": "LOC100773089", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] } ] }, { "uniprot_ac": "A0A9J7K2S5", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] } ] }, { "uniprot_ac": "A0A9J7K3L1", "gene_name": "LOC100755238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] } ] }, { "uniprot_ac": "A0A9J7K3S4", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] } ] }, { "uniprot_ac": "A0A9J7K4N6", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] } ] }, { "uniprot_ac": "A0A9J7K6R5", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] } ] }, { "uniprot_ac": "A0A9J7K7C7", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] } ] }, { "uniprot_ac": "A0A9J7K7D8", "gene_name": "LOC100757073", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] } ] }, { "uniprot_ac": "A0A9J7K851", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] } ] }, { "uniprot_ac": "A0A9J7K8Y1", "gene_name": "Lmtk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] } ] }, { "uniprot_ac": "A0A9J7K953", "gene_name": "Cdkl1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] } ] }, { "uniprot_ac": "A0A9J7KB54", "gene_name": "LOC118237737", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] } ] }, { "uniprot_ac": "A0A9J7KC95", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] } ] }, { "uniprot_ac": "A0A9J7KCM5", "gene_name": "LOC113837018", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] } ] }, { "uniprot_ac": "A0A9J7KCN2", "gene_name": "LOC107977720", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] } ] }, { "uniprot_ac": "A0A9J7KDV7", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] } ] }, { "uniprot_ac": "A0A9J7KE81", "gene_name": "Nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] } ] }, { "uniprot_ac": "A0A9J7KFV8", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] } ] }, { "uniprot_ac": "G3GRI0", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] } ] }, { "uniprot_ac": "G3GRR1", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] } ] }, { "uniprot_ac": "G3GUA6", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] } ] }, { "uniprot_ac": "G3GVI7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] } ] }, { "uniprot_ac": "G3GWJ3", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] } ] }, { "uniprot_ac": "G3GWN1", "gene_name": "LOC100755333", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] } ] }, { "uniprot_ac": "G3GX92", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] } ] }, { "uniprot_ac": "G3GY19", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] } ] }, { "uniprot_ac": "G3GYQ3", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] } ] }, { "uniprot_ac": "G3H3C3", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] } ] }, { "uniprot_ac": "G3H3S6", "gene_name": "Lats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] } ] }, { "uniprot_ac": "G3H5L5", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] } ] }, { "uniprot_ac": "G3H8I4", "gene_name": "Lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] } ] }, { "uniprot_ac": "G3HAZ9", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] } ] }, { "uniprot_ac": "G3HBD4", "gene_name": "LOC100765914", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] } ] }, { "uniprot_ac": "G3HBI7", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] } ] }, { "uniprot_ac": "G3HCC1", "gene_name": "Chek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] } ] }, { "uniprot_ac": "G3HDE8", "gene_name": "Pck2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] } ] }, { "uniprot_ac": "G3HEH4", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] } ] }, { "uniprot_ac": "G3HER3", "gene_name": "Tssk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] } ] }, { "uniprot_ac": "G3HLS6", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] } ] }, { "uniprot_ac": "G3HMY1", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] } ] }, { "uniprot_ac": "G3HT38", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] } ] }, { "uniprot_ac": "G3HTW4", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] } ] }, { "uniprot_ac": "G3HV08", "gene_name": "Cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] } ] }, { "uniprot_ac": "G3HVB0", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] } ] }, { "uniprot_ac": "G3HVN3", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] } ] }, { "uniprot_ac": "G3HX91", "gene_name": "Prkd3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] } ] }, { "uniprot_ac": "G3HXQ8", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] } ] }, { "uniprot_ac": "G3HY42", "gene_name": "Akt3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] } ] }, { "uniprot_ac": "G3HZ18", "gene_name": "LOC100756665", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] } ] }, { "uniprot_ac": "G3HZH7", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] } ] }, { "uniprot_ac": "G3HZU1", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] } ] }, { "uniprot_ac": "G3I0W5", "gene_name": "Stk38l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] } ] }, { "uniprot_ac": "G3I3E2", "gene_name": "Pdik1l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] } ] }, { "uniprot_ac": "G3I3Z8", "gene_name": "Rps6kb2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] } ] }, { "uniprot_ac": "G3I472", "gene_name": "LOC100760228", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] } ] }, { "uniprot_ac": "G3I5H0", "gene_name": "Cilk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] } ] }, { "uniprot_ac": "G3I724", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] } ] }, { "uniprot_ac": "G3I7I8", "gene_name": "Chek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] } ] }, { "uniprot_ac": "G3I8T5", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3I8T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I8T5" } ] } ] }, { "uniprot_ac": "G3IB29", "gene_name": "Irak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IB29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IB29" } ] } ] }, { "uniprot_ac": "G3ICC3", "gene_name": "Cdk20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3ICC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3ICC3" } ] } ] }, { "uniprot_ac": "G3IDN3", "gene_name": "Map3k11", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3IDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IDN3" } ] } ] }, { "uniprot_ac": "G3IFB6", "gene_name": "Pkmyt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IFB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IFB6" } ] } ] }, { "uniprot_ac": "G3IGI9", "gene_name": "Slk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IGI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IGI9" } ] } ] }, { "uniprot_ac": "G3IKJ7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3IKJ7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "G3IKJ7", "database": "UniProtKB", 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annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614673.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003509307", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509307" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KC62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC62" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100773349", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC62", "locus": {} } ], "crossref": [ { "id": "cd03593", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03593", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100773349", "url": "https://www.ncbi.nlm.nih.gov/gene/100773349", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773349", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773349", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HHPCPEN", "url": "https://omabrowser.org/oma/group/HHPCPEN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7KC62", "url": "https://www.orthodb.org/?gene=A0A9J7KC62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22800", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22800", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22800:SF256", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22800:SF256", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003509307", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509307", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KC62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KC62-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC62-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNEVPITRSVLNVNLQHKGKAKNNIKNAFHSNELSFIEQRQKNQKHSKKHKNTTEDISGEENFSSPWRLISSVLGVMCILMAVAIAATVFSTNLSSERQCPMIQQKGPHHPCPENWVWFRCSCYYFSKETLTWRESQQACLSLNSSLIRISREEMEFFSFKNFFWVGVYYNKTSRQWLWENHSVLPSEMFYGLETNTQGNCVTYQSKETCYAEKCTTKQQYICKKYNI", "length": 228, "header": "tr|A0A9J7KC62-1|A0A9J7KC62_CRIGR Isoform 1 of Killer cell lectin-like receptor subfamily E member 1 OS=Cricetulus griseus OX=10029 GN=LOC100773349 PE=4 SV=1 CANONICAL=A0A9J7KC62-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KC62-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC62/entry#A0A9J7KC62-1", "sequence": { "sequence": "MNEVPITRSVLNVNLQHKGKAKNNIKNAFHSNELSFIEQRQKNQKHSKKHKNTTEDISGEENFSSPWRLISSVLGVMCILMAVAIAATVFSTNLSSERQCPMIQQKGPHHPCPENWVWFRCSCYYFSKETLTWRESQQACLSLNSSLIRISREEMEFFSFKNFFWVGVYYNKTSRQWLWENHSVLPSEMFYGLETNTQGNCVTYQSKETCYAEKCTTKQQYICKKYNI", "length": 228, "header": "tr|A0A9J7KC62-1|A0A9J7KC62_CRIGR Isoform 1 of Killer cell lectin-like receptor subfamily E member 1 OS=Cricetulus griseus OX=10029 GN=LOC100773349 PE=4 SV=1 CANONICAL=A0A9J7KC62-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KC62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC62" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KC62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC62" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773349", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773349", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "I3L6H9-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "LOC100519314", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDEEPISYSTLHQDSQQRHTRKNNVKHKFGPNELPLTKKELKHQKPCNTQHRNIAEDVNDTVLSGDFSPLPWRLISSVLGVMCLFLMAVAIAVVVLTASTSSKQSPLIIQQKEKLCLGPHHSCPKNWVWFRCNCYYISKEELTWKDSQRACSSLNSSLIRINREEMHFFSLKYFFWIGVYYNGIDRHWLWENDSLLPSDMFDLPTPQSLQACLSYRSREAYESESCERKQNYICKNHLIYSINSQER", "length": 247 }, "evidence": [ { "id": "A0A9J7KC62", "url": "https://omabrowser.org/oma/group/A0A9J7KC62/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q80ZC8-1", "protein_name": "Killer cell lectin-like receptor subfamily E member 1", "gene_name": "Klre1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNQTLIICSTLNVNSQQKSKAKNSMKNTFHSNELSSIEQRQKYQKHLKKDKKTAEDITGVGNCSPPWRLISSVLFVVCLLLMAVAMVMTIFTTRLSSERSSSNIHQEGLHHPCPENWVWFRCSCYYFSKEKLVWRESQRACLSFNSSLIRMNKEEMDFFSLKSFFWVGVYYDETSKQWLWDDHSVLPSGMFSGLESSPKNFCASYKSKEAYLAENCSTKLMYICKK", "length": 226 }, "evidence": [ { "id": "A0A9J7KC62", "url": "https://omabrowser.org/oma/group/A0A9J7KC62/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CJC7-1", "protein_name": "Killer cell lectin-like receptor subfamily E member 1", "gene_name": "Klre1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEAPVTRSTLNVNSQQKSKAKNKIKNTLNSNELSSIEQRKKYQKHLKKHKNTAEDISGKGNCSPPWRLLSSVLGAMCLLLMAVAMVMTTFTTKSSSERSSSTIQQEGLHHPCPENWVWFRCSCYFFSKEELIWRDSQRACLSLNSSLIRMNKEEMNFFSLKSFFWVGVYYNETRRQWLWEDHSVLPSGLFSKLEANMKNFCASYKSKEAYMEENCANKLTYICKK", "length": 226 }, "evidence": [ { "id": "A0A9J7KC62", "url": "https://omabrowser.org/oma/group/A0A9J7KC62/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KC62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC62" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KC62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC62" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "positive regulation of natural killer cell mediated cytotoxicity", "id": "GO:0045954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045954", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KC62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC62" } ], "pmid": "" }, { "name": "stimulatory C-type lectin receptor signaling pathway", "id": "GO:0002223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002223", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KC62", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC62" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7KC62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC62" }, { "id": "PS50041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-type lectin", "eco_id": "ECO_0000259", "start_pos": 119, "end_pos": 224, "start_aa": "Phe", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 144, "end_pos": 146 }, { "start_pos": 171, "end_pos": 173 }, { "start_pos": 181, "end_pos": 183 }, { "start_pos": 52, "end_pos": 54 }, { "start_pos": 62, "end_pos": 64 }, { "start_pos": 93, "end_pos": 95 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7KCA3-1", "uniprot_ac": "A0A9J7KCA3", "uniprot_id": "A0A9J7KCA3_CRIGR", "mass": { "chemical_mass": 99308.0, "monoisotopic_mass": 99308.0 }, "refseq": { "ac": "XP_035305526", "name": "inter-alpha-trypsin inhibitor heavy chain H3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305526" }, "gene_names": [ { "name": "Itih3", "type": "recommended", "evidence": [ { "id": "A0A9J7KCA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCA3" } ] }, { "name": "Itih3", "type": "synonym", "evidence": [ { "id": "XP_035305526", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305526" } ] } ], "protein_names": [ { "name": "Inter-alpha-trypsin inhibitor heavy chain H3", "type": "recommended", "evidence": [ { "id": "A0A9J7KCA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCA3/entry#names_and_taxonomy" } ] }, { "name": "inter-alpha-trypsin inhibitor heavy chain H3", "type": "synonym", "evidence": [ { "id": "XP_035305526", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305526" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613589.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305526", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305526" } ] }, { "annotation": "May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCA3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCA3#function" }, { "database": "UniProtKB", "id": "ARBA00037051", "url": "https://www.uniprot.org/uniprotkb/ARBA00037051#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCA3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCA3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Itih3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCA3", "locus": {} } ], "crossref": [ { "id": "A0A9J7KCA3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7KCA3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01461", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01461", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100761315", "url": "https://www.ncbi.nlm.nih.gov/gene/100761315", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010600", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010600", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013694", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013694", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050934", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050934", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761315", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761315", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KCA3", "url": "https://www.orthodb.org/?gene=A0A9J7KCA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10338", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10338", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10338:SF115", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10338:SF115", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00092", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00092", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06668", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06668", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08487", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08487", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305526", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305526", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KCA3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KCA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCA3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVTMWWPCLVLALLSGLETSGFPRSPVRLLGKRSLPEGVVDGIEVYSTKISCKVTSRFAHNVVTTRAVNRADKAKEVSFDVELPKTAFITNFTLTIDGVTYPGNIKEKEVAQKQYEKAVSQGKTAGLVKASGRKLEKFTVSVNVAAGSKVTFELTYEELLKRHKGKYEMYLKVQPKQLVRHFEIDAHIFEPQGISMLDAEASFITNDLLGSALTKSFSGKKGHVSFKPSLDQQRSCPTCTDSLLNGDFTIVYDVNRESPGNVQVVNGYFVHFFAPQGLPVVPKNIVFVIDISGSMAGRKIQQTRDALLKILDDMKQGDYMNFIMFSTDVTTWKDSLVQATPANLEEARTFVRSIRSGGGTNINDGLLRGIRMLTDAREQHLVPERSTSIIIMLTDGDANTGESRPEKIQENVRNAIEGKFPLYNLGFGNNLNYNFLETMALENHGLARRIYEDSDANLQLQGFYEEVANPLLTNVEVEYPENAILDLTKNNYPHFYDGSEIVVAGRLVDSDMNNFKADVKGHGALNDLTFTEEVDMKEMDAALKEQGYIFGNYIERLWAYLTIEQLLEKRKNAHGEEKENLTAQALELSLKYHFVTPLTSMVVTKPEDNEDQTSIADKPGEAPYATTSMAYLTSHQSLPSPYYYVDGDPHFIIQVPGKNDTICFNIDEKPGTVLRLIQDPVTGITVTGQIIGDKGSSFYSTTGKTYFGKLGITNARMDFRIEVNTEKIILGTEDELSTFSWLDTVTVTQTGLSVTINRKKNMVVSFGDGVNFVIILHQVWKKHPLHQDFLGFYVVDSHRMSAQTHGLLGQFFHPFDFEVFDIRPGSDPTKPDATMVVKNHRLTVTRGSQKDYRKDASIGTKVTCWFVHNNGEGLIDGVHTDYIIPSLF", "length": 888, "header": "tr|A0A9J7KCA3-1|A0A9J7KCA3_CRIGR Isoform 1 of Inter-alpha-trypsin inhibitor heavy chain H3 OS=Cricetulus griseus OX=10029 GN=Itih3 PE=3 SV=1 CANONICAL=A0A9J7KCA3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KCA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCA3/entry#A0A9J7KCA3-1", "sequence": { "sequence": "MVTMWWPCLVLALLSGLETSGFPRSPVRLLGKRSLPEGVVDGIEVYSTKISCKVTSRFAHNVVTTRAVNRADKAKEVSFDVELPKTAFITNFTLTIDGVTYPGNIKEKEVAQKQYEKAVSQGKTAGLVKASGRKLEKFTVSVNVAAGSKVTFELTYEELLKRHKGKYEMYLKVQPKQLVRHFEIDAHIFEPQGISMLDAEASFITNDLLGSALTKSFSGKKGHVSFKPSLDQQRSCPTCTDSLLNGDFTIVYDVNRESPGNVQVVNGYFVHFFAPQGLPVVPKNIVFVIDISGSMAGRKIQQTRDALLKILDDMKQGDYMNFIMFSTDVTTWKDSLVQATPANLEEARTFVRSIRSGGGTNINDGLLRGIRMLTDAREQHLVPERSTSIIIMLTDGDANTGESRPEKIQENVRNAIEGKFPLYNLGFGNNLNYNFLETMALENHGLARRIYEDSDANLQLQGFYEEVANPLLTNVEVEYPENAILDLTKNNYPHFYDGSEIVVAGRLVDSDMNNFKADVKGHGALNDLTFTEEVDMKEMDAALKEQGYIFGNYIERLWAYLTIEQLLEKRKNAHGEEKENLTAQALELSLKYHFVTPLTSMVVTKPEDNEDQTSIADKPGEAPYATTSMAYLTSHQSLPSPYYYVDGDPHFIIQVPGKNDTICFNIDEKPGTVLRLIQDPVTGITVTGQIIGDKGSSFYSTTGKTYFGKLGITNARMDFRIEVNTEKIILGTEDELSTFSWLDTVTVTQTGLSVTINRKKNMVVSFGDGVNFVIILHQVWKKHPLHQDFLGFYVVDSHRMSAQTHGLLGQFFHPFDFEVFDIRPGSDPTKPDATMVVKNHRLTVTRGSQKDYRKDASIGTKVTCWFVHNNGEGLIDGVHTDYIIPSLF", "length": 888, "header": "tr|A0A9J7KCA3-1|A0A9J7KCA3_CRIGR Isoform 1 of Inter-alpha-trypsin inhibitor heavy chain H3 OS=Cricetulus griseus OX=10029 GN=Itih3 PE=3 SV=1 CANONICAL=A0A9J7KCA3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCA3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCA3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCA3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCA3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761315", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761315", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCA3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCA3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCA3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCA3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "hyaluronan metabolic process", "id": "GO:0030212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030212", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCA3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCA3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 580, "end_pos": 582, "annotation": "n_glycosylation_sequon" }, { "start_pos": 659, "end_pos": 661, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7KCA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCA3" }, { "id": "PS51468", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51468" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VIT", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 158, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7KCA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCA3" }, { "id": "PS50234", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50234" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFA", "eco_id": "ECO_0000259", "start_pos": 284, "end_pos": 467, "start_aa": "Asn", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 580, "end_pos": 582 }, { "start_pos": 659, "end_pos": 661 }, { "start_pos": 91, "end_pos": 93 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7KCA6-1", "uniprot_ac": "A0A9J7KCA6", "uniprot_id": "A0A9J7KCA6_CRIGR", "mass": { "chemical_mass": 120435.0, "monoisotopic_mass": 120435.0 }, "refseq": { "ac": "XP_035306157", "name": "sex comb on midleg-like protein 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306157" }, "gene_names": [ { "name": "LOC100751276", "type": "recommended", "evidence": [ { "id": "A0A9J7KCA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCA6" } ] }, { "name": "LOC100751276", "type": "synonym", "evidence": [ { "id": "XP_035306157", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306157" } ] } ], "protein_names": [ { "name": "Sex comb on midleg-like protein 2 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A9J7KCA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCA6/entry#names_and_taxonomy" } ] }, { "name": "sex comb on midleg-like protein 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035306157", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306157" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035306157", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306157" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCA6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCA6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100751276", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCA6", "locus": {} } ], "crossref": [ { "id": "A0A9J7KCA6", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7KCA6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09578", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09578", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20092", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20092", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100751276", "url": "https://www.ncbi.nlm.nih.gov/gene/100751276", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038348", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038348", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047531", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047531", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050548", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050548", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751276", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751276", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KCA6", "url": "https://www.orthodb.org/?gene=A0A9J7KCA6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12247", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12247", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12247:SF84", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12247:SF84", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02820", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02820", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12140", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12140", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17208", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17208", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035306157", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306157", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7GKA2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GKA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GKA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GKA2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KCA6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KCA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCA6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGQTVNEESMDVKKDNQEKTTHSSTSSVQSNHFDWDKYLKETGSVSAPSEYFRQSLTPPTNEFQVGMKLEARDPRNIGSVCVASVIATTGARLRLRLDGSDNKNDFWRLVDSSDIQPVGTCEQEGDLLQPPLGYRMNVSSWPMFLLRTLTGSELAPAVFFKKEPPSPPLNNFKVGMKIEAVDRKNPFLICPATIGGVKGDQIHITFDGWSGTFDYWCKYDSRDIFPVGWCCLTGDVLQPPGSSAEKKSKSRGATRPWKYGATALESEEAAPEAAEKPKGIVFTNPLEDEDIPVKDDQTAPVWKKPKGRGFTKPGNSEVRLGKSNQPAPVAKKPKGRGFTKPWEDVQTSSDGKKPKGRGLRKPWEDEAKPGKGVQTAPAEKKRKGKTVTKPWKDQAGFIEDAEAGPAEKKRKGKTVTKPWKDQAGFFEDAETGPAEKKRKGKTVTKPWKDQTGFFEDAESGSAEKKRKGKTVTKPWKDQTGFFEDVEAGPAEKKRKGKTVTKPLIDQTGDFEDEEADPADKKLKCKTVTKLWKGLAGFFEDEEAGPAEKKLKEKTATTPWKGLSVVFVGEEECPAEKKRKGKTGTKSWKDQGRFFEDKEAAQAEQKRKRKRASKFWKEQAKLLEDEEAIPALFSALSMKSTENTPPSSSEQPKSSTSEKTKSSTSKGAQSSKKSPRKTTIVLPAAKTSKKSGQPKPTGDTSAPKKRMEVKIVFPKKKGGKKEKCIPVVSSTSSASLSSLMRSSSSDNSSVVPSKIVMSTVCVYINKHGDCGPYLDPQKVRQLPDHFGPGPVNVILQRTVQACVDCAIDTKTVFLLLKPDNRGGEIITAFFDAKVHTVQLPPVNSASFVLRFLENFCHSLQCDKFLSSQPFKPRVRIHTPATDLDQNKPVGEELKERRSLKRFSQRPLPASSKVPRKTGRASKVLSPEGHGMSKTKSFPETSENSSVGDSLYPAHTSVSKNVSEIVSNTSSTSIVMKKSSTSTTYKRIKFQWKKKNEASSYIAVPDPSVLKQGFCKDPSTWSVDEVIQFMKHTDPHISGPLADIFRQHEIDGKALLLLKSELMMKYMGLKLGPALKICYYIEKLKEVKYN", "length": 1088, "header": "tr|A0A9J7KCA6-1|A0A9J7KCA6_CRIGR Isoform 1 of Sex comb on midleg-like protein 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100751276 PE=3 SV=1 CANONICAL=A0A9J7KCA6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7GKA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCA6/entry#A0A9J7GKA2-1", "sequence": { "sequence": "MGQTVNEESMDVKKDNQEKTTHSSTSSVQSNHFDWDKYLKETGSVSAPSEYFRQSLTPPTNEFQVGMKLEARDPRNIGSVCVASVIATTGARLRLRLDGSDNKNDFWRLVDSSDIQPVGTCEQEGDLLQPPLGYRMNVSSWPMFLLRTLTGSELAPAVFFKKEPPSPPLNNFKVGMKIEAVDRKNPFLICPATIGGVKGDQIHITFDGWSGTFDYWCKYDSRDIFPVGWCCLTGDVLQPPGSSAEKKSKSRGATRPWKYGATALESEEAAPEAAEKPKGIVFTNPLEDEDIPVKDDQTAPVWKKPKGRGFTKPGNSEVRLGKSNQPAPVAKKPKGRGFTKPWEDVQTSSDGKKPKGRGLRKPWEDEAKPGKGVQTAPAEKKRKGKTVTKPWKDQAGFIEDAEAGPAEKKRKGKTVTKPWKDQAGFFEDAETGPAEKKRKGKTVTKPWKDQTGFFEDAESGSAEKKRKGKTVTKPWKDQTGFFEDVEAGPAEKKRKGKTVTKPLIDQTGDFEDEEADPAEKKLKEKTATTPWKGLSVVFVGEEECPAEKKRKGKTGTKSWKDQGRFFEDKEAAQAEQKRKRKRASKFWKEQAKLLEDEEAIPALFSALSMKSTENTPPSSSEQPKSSTSEKTKSSTSKGAQSSKKSPRKTTIVLPAAKTSKKSGQPKPTGDTSAPKKRMEVKIVFPKKKGGKKEKCIPVVSSTSSASLSSLMRSSSSDNSSVVPSKIVMSTVCVYINKHGDCGPYLDPQKVRQLPDHFGPGPVNVILQRTVQACVDCAIDTKTVFLLLKPDNRGGEIITAFFDAKVHTVQLPPVNSASFVLRFLENFCHSLQCDKFLSSQPFKPRVRIHTPATDLDQNKPVGEELKERRSLKRFSQRPLPASSKVPRKTGRASKVLSPEGHGMSKTKSFPETSENSSVGDSLYPAHTSVSKNVSEIVSNTSSTSIVMKKSSTSTTYKRIKFQWKKKNEASSYIAVPDPSVLKQGFCKDPSTWSVDEVIQFMKHTDPHISGPLADIFRQHEIDGKALLLLKSELMMKYMGLKLGPALKICYYIEKLKEVKYN", "length": 1060, "header": "tr|A0A9J7GKA2-1|A0A9J7GKA2_CRIGR Computationally mapped isoform of Sex comb on midleg-like protein 2 isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC100751276 PE=3 SV=1 CANONICAL=A0A9J7KCA6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KCA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCA6/entry#A0A9J7KCA6-1", "sequence": { "sequence": "MGQTVNEESMDVKKDNQEKTTHSSTSSVQSNHFDWDKYLKETGSVSAPSEYFRQSLTPPTNEFQVGMKLEARDPRNIGSVCVASVIATTGARLRLRLDGSDNKNDFWRLVDSSDIQPVGTCEQEGDLLQPPLGYRMNVSSWPMFLLRTLTGSELAPAVFFKKEPPSPPLNNFKVGMKIEAVDRKNPFLICPATIGGVKGDQIHITFDGWSGTFDYWCKYDSRDIFPVGWCCLTGDVLQPPGSSAEKKSKSRGATRPWKYGATALESEEAAPEAAEKPKGIVFTNPLEDEDIPVKDDQTAPVWKKPKGRGFTKPGNSEVRLGKSNQPAPVAKKPKGRGFTKPWEDVQTSSDGKKPKGRGLRKPWEDEAKPGKGVQTAPAEKKRKGKTVTKPWKDQAGFIEDAEAGPAEKKRKGKTVTKPWKDQAGFFEDAETGPAEKKRKGKTVTKPWKDQTGFFEDAESGSAEKKRKGKTVTKPWKDQTGFFEDVEAGPAEKKRKGKTVTKPLIDQTGDFEDEEADPADKKLKCKTVTKLWKGLAGFFEDEEAGPAEKKLKEKTATTPWKGLSVVFVGEEECPAEKKRKGKTGTKSWKDQGRFFEDKEAAQAEQKRKRKRASKFWKEQAKLLEDEEAIPALFSALSMKSTENTPPSSSEQPKSSTSEKTKSSTSKGAQSSKKSPRKTTIVLPAAKTSKKSGQPKPTGDTSAPKKRMEVKIVFPKKKGGKKEKCIPVVSSTSSASLSSLMRSSSSDNSSVVPSKIVMSTVCVYINKHGDCGPYLDPQKVRQLPDHFGPGPVNVILQRTVQACVDCAIDTKTVFLLLKPDNRGGEIITAFFDAKVHTVQLPPVNSASFVLRFLENFCHSLQCDKFLSSQPFKPRVRIHTPATDLDQNKPVGEELKERRSLKRFSQRPLPASSKVPRKTGRASKVLSPEGHGMSKTKSFPETSENSSVGDSLYPAHTSVSKNVSEIVSNTSSTSIVMKKSSTSTTYKRIKFQWKKKNEASSYIAVPDPSVLKQGFCKDPSTWSVDEVIQFMKHTDPHISGPLADIFRQHEIDGKALLLLKSELMMKYMGLKLGPALKICYYIEKLKEVKYN", "length": 1088, "header": "tr|A0A9J7KCA6-1|A0A9J7KCA6_CRIGR Isoform 1 of Sex comb on midleg-like protein 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100751276 PE=3 SV=1 CANONICAL=A0A9J7KCA6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCA6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCA6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751276", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751276", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCA6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCA6" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCA6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCA6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCA6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCA6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCA6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCA6" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCA6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCA6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { 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"synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 137, "end_pos": 139 }, { "start_pos": 746, "end_pos": 748 }, { "start_pos": 942, "end_pos": 944 }, { "start_pos": 959, "end_pos": 961 }, { "start_pos": 966, "end_pos": 968 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7KCC0-1", "uniprot_ac": "A0A9J7KCC0", "uniprot_id": "A0A9J7KCC0_CRIGR", "mass": { "chemical_mass": 42700.0, "monoisotopic_mass": 42700.0 }, "refseq": { "ac": "XP_035306187", "name": "erythroid transcription factor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306187" }, "gene_names": [ { "name": "Gata1", "type": "recommended", "evidence": [ { "id": "A0A9J7KCC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCC0" } ] }, { "name": "Gata1", "type": "synonym", "evidence": [ { "id": "XP_035306187", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306187" } ] } ], "protein_names": [ { "name": "Erythroid transcription factor", "type": "synonym", "evidence": [ { "id": "A0A9J7KCC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCC0/entry#names_and_taxonomy" } ] }, { "name": "erythroid transcription factor", "type": "synonym", "evidence": [ { "id": "XP_035306187", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306187" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035306187", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306187" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCC0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCC0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Gata1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCC0", "locus": {} } ], "crossref": [ { "id": "A0A9J7KCC0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7KCC0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00202", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00202", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100763974", "url": "https://www.ncbi.nlm.nih.gov/gene/100763974", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000679", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000679", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013088", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013088", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039355", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039355", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763974", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763974", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YSKTGLY", "url": "https://omabrowser.org/oma/group/YSKTGLY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7KCC0", "url": "https://www.orthodb.org/?gene=A0A9J7KCC0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10071", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10071", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10071:SF190", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10071:SF190", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00320", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00320", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035306187", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306187", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KCC0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KCC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCC0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFPGLGALGSSEPLPQFVDSSLVSSPPDPGPFFSGPEGLDVAASSTSPSTGTGAATALAYYRDTESYRHSPVFQVYPLLNCMEGIPGGSSYASWAYSKTGLYPASTVCSSHEDAPPQTLEDPDGKSSTTFLETLKTERLSPDLLTLGTALPASLPVNSSGYGAPDFPGPFFSPTGSPLNSAAYSSPKFHGSLPLAPCEARECVNCGATATPLWRRDRTGHYLCNACGLYHKMNGQNRPLIRPKKRLIVSKRAGTQCTNCQTTTTTLWRRNASGDPVCNACGLYYKLHQVNRPLTMRKDGIQTRNRKASGKGKKKRGSSLGGAGAAEGPASGFMVVAGGSSSGNCGEVASGLTLSTAGTAHLYQGLGPVVLSGPVSHLMPFSGPLLGSPTASFPTGPVPPTTSTTVVAPLSS", "length": 412, "header": "tr|A0A9J7KCC0-1|A0A9J7KCC0_CRIGR Isoform 1 of Erythroid transcription factor OS=Cricetulus griseus OX=10029 GN=Gata1 PE=4 SV=1 CANONICAL=A0A9J7KCC0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KCC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCC0/entry#A0A9J7KCC0-1", "sequence": { "sequence": "MDFPGLGALGSSEPLPQFVDSSLVSSPPDPGPFFSGPEGLDVAASSTSPSTGTGAATALAYYRDTESYRHSPVFQVYPLLNCMEGIPGGSSYASWAYSKTGLYPASTVCSSHEDAPPQTLEDPDGKSSTTFLETLKTERLSPDLLTLGTALPASLPVNSSGYGAPDFPGPFFSPTGSPLNSAAYSSPKFHGSLPLAPCEARECVNCGATATPLWRRDRTGHYLCNACGLYHKMNGQNRPLIRPKKRLIVSKRAGTQCTNCQTTTTTLWRRNASGDPVCNACGLYYKLHQVNRPLTMRKDGIQTRNRKASGKGKKKRGSSLGGAGAAEGPASGFMVVAGGSSSGNCGEVASGLTLSTAGTAHLYQGLGPVVLSGPVSHLMPFSGPLLGSPTASFPTGPVPPTTSTTVVAPLSS", "length": 412, "header": "tr|A0A9J7KCC0-1|A0A9J7KCC0_CRIGR Isoform 1 of Erythroid transcription factor OS=Cricetulus griseus OX=10029 GN=Gata1 PE=4 SV=1 CANONICAL=A0A9J7KCC0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 401, "start_aa": "Thr", "end_pos": 401, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr401", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCC0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCC0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCC0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCC0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763974", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763974", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BI59-1", "protein_name": "GATA binding protein 1", "gene_name": "GATA1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEFPGLGALGTSEPLPQFMDPALVSSPPESGVFFPPGSEGLDTAASSTAASTATAAAAALAYYRDAEAYRHSPVFQVYPLINCMEGIPGGSPYASWAYGKTGLYPASTVCPTREDSSPQASEDLDGKGGSSFLETLKTERMSPDLLTLGTAPPSSIPVPSSAYGGPDFSSTYFSPTGSPLNPAPYSSPKLRGTLPLTPCEARECVNCGATATPLWRRDRTGHYLCNACGLYHKMNGQNRPLIRPKKRLIVSKRAGTQCTNCQTTTTTLWRRNASGDPVCNACGLYYKLHQVNRPLTMRKDGIQTRNRKASGKGKKKRGSSLGATGAAEGPSGGFMVVAGGSSSGNCGEVTSGLTLGPPGTAHVYQGLGPVVLSGPVSHIMPFPGPLLGSPTGSFPTGPVPPTTTTTVVAPLSS", "length": 413 }, "evidence": [ { "id": "A0A9J7KCC0", "url": "https://omabrowser.org/oma/group/A0A9J7KCC0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "I3LEA0-1", "protein_name": "GATA binding protein 1", "gene_name": "GATA1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEFPGLGALGTSEPLPQFMDPALVSSPPESGVFFSSGPEGLDTAVSTAPGTATAAAAALAYYRDAEAYRHSPVFQVYPLLNCMEGIPGGSPYAGWAYGKPGLYPASTVCPIREDSPPQAAEDLDGKGGSSFLETLKTERLSPDLLTLGPALTSSIPVPSSAYGGPDFSSTFFSPTGSPLNPAAYSSPKLRGTLPLTPCEARECVNCGATATPLWRRDRTGHYLCNACGLYHKMNGQNRPLIRPKKRLIVSKRAGTQCTNCQTTTTTLWRRNASGDPVCNACGLYYKLHQVNRPLTMRKDGIQTRNRKASGKGKKKRGSSLGGTGAAEGPAGGFMVVAGGSSSGNCGEAASGLTLGPPGTAHLYQGLGPVVLSGPVSHLMPFPGPLLGSPTGSFTTGPVPPTTTTTVVAPLSS", "length": 412 }, "evidence": [ { "id": "A0A9J7KCC0", "url": "https://omabrowser.org/oma/group/A0A9J7KCC0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P15976-1", "protein_name": "Erythroid transcription factor", "gene_name": "GATA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEFPGLGSLGTSEPLPQFVDPALVSSTPESGVFFPSGPEGLDAAASSTAPSTATAAAAALAYYRDAEAYRHSPVFQVYPLLNCMEGIPGGSPYAGWAYGKTGLYPASTVCPTREDSPPQAVEDLDGKGSTSFLETLKTERLSPDLLTLGPALPSSLPVPNSAYGGPDFSSTFFSPTGSPLNSAAYSSPKLRGTLPLPPCEARECVNCGATATPLWRRDRTGHYLCNACGLYHKMNGQNRPLIRPKKRLIVSKRAGTQCTNCQTTTTTLWRRNASGDPVCNACGLYYKLHQVNRPLTMRKDGIQTRNRKASGKGKKKRGSSLGGTGAAEGPAGGFMVVAGGSGSGNCGEVASGLTLGPPGTAHLYQGLGPVVLSGPVSHLMPFPGPLLGSPTGSFPTGPMPPTTSTTVVAPLSS", "length": 413 }, "evidence": [ { "id": "A0A9J7KCC0", "url": "https://omabrowser.org/oma/group/A0A9J7KCC0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P17679-1", "protein_name": "Erythroid transcription factor", "gene_name": "Gata1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFPGLGALGTSEPLPQFVDSALVSSPSDSTGFFSSGPEGLDAASSSTSPNAATAAASALAYYREAEAYRHSPVFQVYPLLNSMEGIPGGSPYASWAYGKTALYPASTVCPSHEDAPSQALEDQEGKSNNTFLDTLKTERLSPDLLTLGTALPASLPVTGSAYGGADFPSPFFSPTGSPLSSAAYSSPKFHGSLPLAPCEARECVNCGATATPLWRRDRTGHYLCNACGLYHKMNGQNRPLIRPKKRMIVSKRAGTQCTNCQTTTTTLWRRNASGDPVCNACGLYFKLHQVNRPLTMRKDGIQTRNRKASGKGKKKRGSNLAGAGAAEGPAGGFMVVAGSSSSGNCGEVASGLALGTAGTAHLYQGLGPVVLSGPVSHLMPFPGPLLGSPTTSFPTGPAPTTSSTSVIAPLSS", "length": 413 }, "evidence": [ { "id": "A0A9J7KCC0", "url": "https://omabrowser.org/oma/group/A0A9J7KCC0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P43429-1", "protein_name": "Erythroid transcription factor", "gene_name": "Gata1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDFPGLGALGTSEPLPQFVDSALVSSTSDSAGFFSSGPESLDTASSSTSPNAATAAATALAYYREAEAYRHSPVFQVYPLLNSMEGIPGSSPYASWAYSKTALYPASTVCPSHEDAPSQTLEDPDGKNNNTFLETLKTERLSPDLLTLGTALPTSLPVTSSAYGGADFPSPFFSPTGSPLSSAAYSSPKFHGSLPLAPCEARECVNCGATATPLWRRDRTGHYLCNACGLYHKMNGQNRPLIRPKKRMIVSKRAGTQCTNCQTTTTTLWRRNASGDPVCNACGLYYKLHQVNRPLTMRKDGIQTRNRKASGKGKKKRGSSLAGAGAAEGPAGGFMVVAGGSSSGNCGEVAPGLTLGTAGTAHLYQGLGPVVLSGPVSHLMSFPGPLLGSPTASFPTGPVPTTTSTSVVSPLSS", "length": 413 }, "evidence": [ { "id": "A0A9J7KCC0", "url": "https://omabrowser.org/oma/group/A0A9J7KCC0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCC0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCC0" } ], "pmid": "" }, { "name": "DNA-templated 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}, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCC0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCC0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCC0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCC0" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCC0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCC0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCC0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCC0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7KCC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCC0" }, { "id": "PS50114", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50114" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GATA-type", "eco_id": "ECO_0000259", "start_pos": 197, "end_pos": 252, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" } ], 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} ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7KCC3-1", "uniprot_ac": "A0A9J7KCC3", "uniprot_id": "A0A9J7KCC3_CRIGR", "mass": { "chemical_mass": 25323.0, "monoisotopic_mass": 25323.0 }, "refseq": { "ac": "XP_035304623", "name": "NKG2-D type II integral membrane protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304623" }, "gene_names": [ { "name": "LOC100773926", "type": "recommended", "evidence": [ { "id": "A0A9J7KCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCC3" } ] }, { "name": "LOC100773926", "type": "synonym", "evidence": [ { "id": "XP_035304623", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304623" } ] } ], "protein_names": [ { "name": "NKG2-D type II integral membrane protein", "type": "recommended", "evidence": [ { "id": "A0A9J7KCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCC3/entry#names_and_taxonomy" } ] }, { "name": "Killer cell lectin-like receptor subfamily K member 1", "type": "synonym", "evidence": [ { "id": "A0A9J7KCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCC3/entry#names_and_taxonomy" } ] }, { "name": "NK cell receptor D", "type": "synonym", "evidence": [ { "id": "A0A9J7KCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCC3/entry#names_and_taxonomy" } ] }, { "name": "NKG2-D type II integral membrane protein", "type": "synonym", "evidence": [ { "id": "XP_035304623", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304623" } ] }, { "name": "NKG2-D-activating NK receptor", "type": "synonym", "evidence": [ { "id": "A0A9J7KCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCC3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 2% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304623", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304623" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCC3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCC3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100773926", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCC3", "locus": {} } ], "crossref": [ { "id": "A0A9J7KCC3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7KCC3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03593", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03593", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100773926", "url": "https://www.ncbi.nlm.nih.gov/gene/100773926", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042169", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042169", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773926", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773926", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KCC3", "url": "https://www.orthodb.org/?gene=A0A9J7KCC3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47494", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47494", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47494:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47494:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304623", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304623", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KCC3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KCC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCC3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNKCHNYKPKPKKRNASQGWQKQRSALLTFQPRQHGIIRRSSPTEEFKISPLFVSRVIAAAMAIRFIIITLIWFAVFITLLCNNEVPISSREGYCDQCPNDWICYRNNCYQFFNENKNWKQSQASCLSQNSTLLKIYSKEDQDFFKLVKSYHWIGLFQTQANGSWQWEDGSTLSPNHLTLVEMQNGSCAVYGSSFKAYTEDCSALNTYICMKKAVLGLH", "length": 219, "header": "tr|A0A9J7KCC3-1|A0A9J7KCC3_CRIGR Isoform 1 of NKG2-D type II integral membrane protein OS=Cricetulus griseus OX=10029 GN=LOC100773926 PE=4 SV=1 CANONICAL=A0A9J7KCC3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KCC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCC3/entry#A0A9J7KCC3-1", "sequence": { "sequence": "MNKCHNYKPKPKKRNASQGWQKQRSALLTFQPRQHGIIRRSSPTEEFKISPLFVSRVIAAAMAIRFIIITLIWFAVFITLLCNNEVPISSREGYCDQCPNDWICYRNNCYQFFNENKNWKQSQASCLSQNSTLLKIYSKEDQDFFKLVKSYHWIGLFQTQANGSWQWEDGSTLSPNHLTLVEMQNGSCAVYGSSFKAYTEDCSALNTYICMKKAVLGLH", "length": 219, "header": "tr|A0A9J7KCC3-1|A0A9J7KCC3_CRIGR Isoform 1 of NKG2-D type II integral membrane protein OS=Cricetulus griseus OX=10029 GN=LOC100773926 PE=4 SV=1 CANONICAL=A0A9J7KCC3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCC3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCC3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7KCD0-1", "uniprot_ac": "A0A9J7KCD0", "uniprot_id": "A0A9J7KCD0_CRIGR", "mass": { "chemical_mass": 68840.0, "monoisotopic_mass": 68840.0 }, "refseq": { "ac": "XP_035306225", "name": "oviduct-specific glycoprotein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306225" }, "gene_names": [ { "name": "Ovgp1", "type": "recommended", "evidence": [ { "id": "A0A9J7KCD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD0" } ] }, { "name": "Ovgp1", "type": "synonym", "evidence": [ { "id": "XP_035306225", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306225" } ] } ], "protein_names": [ { "name": "Oviduct-specific glycoprotein", "type": "recommended", "evidence": [ { "id": "A0A9J7KCD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD0/entry#names_and_taxonomy" } ] }, { "name": "Estrogen-dependent oviduct protein", "type": "synonym", "evidence": [ { "id": "A0A9J7KCD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD0/entry#names_and_taxonomy" } ] }, { "name": "Oviductal glycoprotein", "type": "synonym", "evidence": [ { "id": "A0A9J7KCD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD0/entry#names_and_taxonomy" } ] }, { "name": "Oviductin", "type": "synonym", "evidence": [ { "id": "A0A9J7KCD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD0/entry#names_and_taxonomy" } ] }, { "name": "oviduct-specific glycoprotein", "type": "synonym", "evidence": [ { "id": "XP_035306225", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306225" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035306225", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306225" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCD0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ovgp1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD0", "locus": {} } ], "crossref": [ { "id": "A0A9J7KCD0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7KCD0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02872", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02872", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100773377", "url": "https://www.ncbi.nlm.nih.gov/gene/100773377", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001223", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001223", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011583", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011583", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029070", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029070", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773377", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773377", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KCD0", "url": "https://www.orthodb.org/?gene=A0A9J7KCD0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11177", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11177", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11177:SF385", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11177:SF385", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00704", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00704", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035306225", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306225", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KCD0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KCD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSCWKGGITGLVLLMKHNDGTAYKLVCYFTNWAHSRPGPASVLPRDLDPFLCTHLIFAFASMSNNQIVANNLQDEKILYPEFNKLKERNRALKTLLSIGGWNFGTSRFTTMLSTLASREEFIGSVVSFLRTHGFDGLDLFFLYPGLRGSPMNDRWNFLFLIEELQFAFEKEALLTQRPRLLLSAAVSGIPYIIQTSYDVPLLGRRLDFINVLSYDLHGSWEKSTGHNSPLFSLPEDPKSSAYAMNYWRNLGAPADKLLMGFPAYGRTFHLTRESKNGLEAASMGPASPGKYTKQAGFLAYYEVCSFIQQAEKHWIDHQYVPYAYKGKEWVGYDDTISFSYKAMFVKKEHFGGAMVWTLDMDDVKGTFCGNGPFPLVHILNEVLVQAEFNLTPLPQFWFTLPVNSSGPGSESLPVTEELTTDTVKILPPGGEAMATEVHRKYEKVTTIPNGGFVTPGGTTSPATYAVALERNTVAPGAKTTTSLDLLSETMTGMTVTVQTQTTGGETTVTVGNQSVTPGGEIKATVGNQSVTPGGETKATVGNQSVTPGEETKATVGNQSVTPPGMDTTLIYLQTVTPSEKGTSRKKAVVLEKVIVSPREMSVMPNRQNTALKPESLINEVETHSQDG", "length": 627, "header": "tr|A0A9J7KCD0-1|A0A9J7KCD0_CRIGR Isoform 1 of Oviduct-specific glycoprotein OS=Cricetulus griseus OX=10029 GN=Ovgp1 PE=3 SV=1 CANONICAL=A0A9J7KCD0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KCD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD0/entry#A0A9J7KCD0-1", "sequence": { "sequence": "MSCWKGGITGLVLLMKHNDGTAYKLVCYFTNWAHSRPGPASVLPRDLDPFLCTHLIFAFASMSNNQIVANNLQDEKILYPEFNKLKERNRALKTLLSIGGWNFGTSRFTTMLSTLASREEFIGSVVSFLRTHGFDGLDLFFLYPGLRGSPMNDRWNFLFLIEELQFAFEKEALLTQRPRLLLSAAVSGIPYIIQTSYDVPLLGRRLDFINVLSYDLHGSWEKSTGHNSPLFSLPEDPKSSAYAMNYWRNLGAPADKLLMGFPAYGRTFHLTRESKNGLEAASMGPASPGKYTKQAGFLAYYEVCSFIQQAEKHWIDHQYVPYAYKGKEWVGYDDTISFSYKAMFVKKEHFGGAMVWTLDMDDVKGTFCGNGPFPLVHILNEVLVQAEFNLTPLPQFWFTLPVNSSGPGSESLPVTEELTTDTVKILPPGGEAMATEVHRKYEKVTTIPNGGFVTPGGTTSPATYAVALERNTVAPGAKTTTSLDLLSETMTGMTVTVQTQTTGGETTVTVGNQSVTPGGEIKATVGNQSVTPGGETKATVGNQSVTPGEETKATVGNQSVTPPGMDTTLIYLQTVTPSEKGTSRKKAVVLEKVIVSPREMSVMPNRQNTALKPESLINEVETHSQDG", "length": 627, "header": "tr|A0A9J7KCD0-1|A0A9J7KCD0_CRIGR Isoform 1 of Oviduct-specific glycoprotein OS=Cricetulus griseus OX=10029 GN=Ovgp1 PE=3 SV=1 CANONICAL=A0A9J7KCD0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 454, "start_aa": "Thr", "end_pos": 454, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr454", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 516, "start_aa": "Thr", "end_pos": 516, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr516", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 531, "start_aa": "Thr", "end_pos": 531, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr531", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 546, "start_aa": "Thr", "end_pos": 546, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr546", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCD0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCD0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773377", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773377", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCD0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD0" } ], "pmid": "" }, { "name": "transport vesicle", "id": "GO:0030133", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030133", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCD0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCD0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD0" } ], "pmid": "" }, { "name": "single fertilization", "id": "GO:0007338", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007338", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCD0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD0" } ], "pmid": "" }, { "name": "chitin catabolic process", "id": "GO:0006032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006032", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCD0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "chitinase activity", "id": "GO:0004568", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004568", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCD0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD0" } ], "pmid": "" }, { "name": "chitin binding", "id": "GO:0008061", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008061", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCD0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" }, { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" }, { "start_pos": 512, "end_pos": 514, "annotation": "n_glycosylation_sequon" }, { "start_pos": 527, "end_pos": 529, "annotation": "n_glycosylation_sequon" }, { "start_pos": 542, "end_pos": 544, "annotation": "n_glycosylation_sequon" }, { "start_pos": 557, "end_pos": 559, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7KCD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD0" }, { "id": "PS51910", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51910" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GH18", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 386, "start_aa": "Tyr", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 454, 516, 531, 546 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 389, "end_pos": 391 }, { "start_pos": 403, "end_pos": 405 }, { "start_pos": 512, "end_pos": 514 }, { "start_pos": 527, "end_pos": 529 }, { "start_pos": 542, "end_pos": 544 }, { "start_pos": 557, "end_pos": 559 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7KCD4-1", "uniprot_ac": "A0A9J7KCD4", "uniprot_id": "A0A9J7KCD4_CRIGR", "mass": { "chemical_mass": 204617.0, "monoisotopic_mass": 204617.0 }, "refseq": { "ac": "XP_035306241", "name": "nestin isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306241" }, "gene_names": [ { "name": "Nes", "type": "recommended", "evidence": [ { "id": "A0A9J7KCD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD4" } ] }, { "name": "Nes", "type": "synonym", "evidence": [ { "id": "XP_035306241", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306241" } ] } ], "protein_names": [ { "name": "Nestin", "type": "recommended", "evidence": [ { "id": "A0A9J7KCD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD4/entry#names_and_taxonomy" } ] }, { "name": "nestin isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035306241", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306241" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035306241", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306241" } ] }, { "annotation": "Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD4#function" }, { "database": "UniProtKB", "id": "ARBA00058665", "url": "https://www.uniprot.org/uniprotkb/ARBA00058665#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Nes", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD4", "locus": {} } ], "crossref": [ { "id": "100761741", "url": "https://www.ncbi.nlm.nih.gov/gene/100761741", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018039", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018039", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031211", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031211", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761741", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761741", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KCD4", "url": "https://www.orthodb.org/?gene=A0A9J7KCD4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47051", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47051", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47051:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47051:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035306241", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306241", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KCD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KCD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGCVGEESFQLWELNRRLEAYLTRVKTLEEQNQLLSAELGGLRAQSGDASWRARADDELAALRVLVDQRWREKHEAEVQRDNLAEELEGVAGRCQQVRLARERTSEEAACSRRALEAEKSAQGWLSSRVAELEREVEAVRAAHEEERAHLNAQAACAPRRLPVPPRGPPARVPEVEELARRLGEAWRGAVRGYQERVAHMESSLGQARERLGRAVRGAREGRLELQQLQAERDGLLERREALEQRLEGRWQDRLQATEKFQLAVDALEQEKQGLQSQIAQILEGGQQLAHLKMSLSLEVATYRTLLEAENSRLQTPGRGSQASLGFQDPKLKLHFLGTPEDQHLGSVLPVLSPTPLPSPLPDTLETPVTPFLKTQEFLQAQTPTLASTPIPPMTEAPFPTKAEVRAQDVPLSLLQTQGGRHQAPEPLWSEATAPVSTGVLEQLEEAGGKQPGHFPKDATTSAPSLNLHLPVLEAKDVDSSESRVSTIFQEDEGQIWELAEKEAAIEVKVESSLAQETQEDGLDAEEIQDSQGPLQKETLETLVEEPLMSLKIQSHETPGKENCNSLRSVDENQGILKSPEEEKQTLLKSLEEKDVEVEKTLEKGVPELSKPLGKEDPRMEGQELISPEGTLETLPFIGKENEEVMRSSEEKNLESLTAFKKESQPPLGCPEEEVQRVERLIEKEGQESLRSLEEEDQETYRPLEKENGEPLKSVEEEVQLVERLIEKEGQESLRSLEEEDQETYRPLEKENGEPLKSVEEELQLVERLIEKEGQESLGSLEEEDQETYRPLEKENGEPLKSVEEEVQLVERLIEKEGQESLGSLEEEDQETYRPLEKEDQKNQESLRSLDENQDTIMPLESKTQKPLKSLEVEEEQRIVKPLEKVSQGSIGSLEKENVELLGSLEDNDQMTESLLKKGTQESLGSHEDTNQETQDPQRFLEEEGQGIVKQLEKENQSFLGSLEEEQVVKRSLERENHEPLSSVEKKDQMTKSLLEKESQDSGKSLEEDQEAFRSLGKEDPESLQSLEEQDQEIQRYLQQETQQILGTLGSAQMASKLPENVGPELLKSLGNDQEIVRSLEEQNQESLVSLKETSVETVKSSEIENTEPLKNAEEDLEIINSIEAQESLWSTEVTRETTKPLEKEIQESLGFVDGNQEMLRPLDRENQELRSLGKWHLETVDSSEGMEEGRQRLEVEAVLETEEHQELLGSLEEGEQGLPGCVNQQGWEDMAVEHAAADQGPTLGRAGVESEDEAELPLSGQGEKKEGAEERERQLDAMGEAWSLEISEPQEQRVPSEEGSPGALQDLEGQPEQVGALEVPVGEGIPEVTEPLLQDEDIAQTGEQDSIEVTLGSENATRAELVLEQEVVGLGGPTHLAREEANHPSLGEESVEAKIAQDLEGSGKEPTEAGALESESSELPRASSDTLESKGCRESEPVVGWAVEEASVETSDHEGSGSPQPRPSETEGDEGTQAALAPPDPKLVEPCSPTPILEDACEQQPQADGIQEAGWQLEGGSEALERVEDEQEFGLGEIPEGLQDWEESREESEADELGETLPDSTPLGLYLRSPTSPKWDLAGEQRLSPQGEARKEGWGPAVLSNPSGEEEQGHDSDLSSEEFEDLGTEVSLLPGLPKEVPPVPEPECWDQGGESDGFADEEESGEEGEEGTESGAQWWGPGSSGGGFKVQHITQRGDLLEHESVGVSGPWDDDLRGATANISVTGLETESQDSAEPSGSEGSESVSSEGEDQVPDHLGAPQGVTNMVPVGGDTFGISGQGPRLESEHMNGRMENGLEQSEGQGVLDGHQDQEYPSQEQEVGALKAPLVGSAVHQGPSQSLEFPLSGVDGDSWSSGED", "length": 1855, "header": "tr|A0A9J7KCD4-1|A0A9J7KCD4_CRIGR Isoform 1 of Nestin OS=Cricetulus griseus OX=10029 GN=Nes PE=3 SV=1 CANONICAL=A0A9J7KCD4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KCD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD4/entry#A0A9J7KCD4-1", "sequence": { "sequence": "MEGCVGEESFQLWELNRRLEAYLTRVKTLEEQNQLLSAELGGLRAQSGDASWRARADDELAALRVLVDQRWREKHEAEVQRDNLAEELEGVAGRCQQVRLARERTSEEAACSRRALEAEKSAQGWLSSRVAELEREVEAVRAAHEEERAHLNAQAACAPRRLPVPPRGPPARVPEVEELARRLGEAWRGAVRGYQERVAHMESSLGQARERLGRAVRGAREGRLELQQLQAERDGLLERREALEQRLEGRWQDRLQATEKFQLAVDALEQEKQGLQSQIAQILEGGQQLAHLKMSLSLEVATYRTLLEAENSRLQTPGRGSQASLGFQDPKLKLHFLGTPEDQHLGSVLPVLSPTPLPSPLPDTLETPVTPFLKTQEFLQAQTPTLASTPIPPMTEAPFPTKAEVRAQDVPLSLLQTQGGRHQAPEPLWSEATAPVSTGVLEQLEEAGGKQPGHFPKDATTSAPSLNLHLPVLEAKDVDSSESRVSTIFQEDEGQIWELAEKEAAIEVKVESSLAQETQEDGLDAEEIQDSQGPLQKETLETLVEEPLMSLKIQSHETPGKENCNSLRSVDENQGILKSPEEEKQTLLKSLEEKDVEVEKTLEKGVPELSKPLGKEDPRMEGQELISPEGTLETLPFIGKENEEVMRSSEEKNLESLTAFKKESQPPLGCPEEEVQRVERLIEKEGQESLRSLEEEDQETYRPLEKENGEPLKSVEEEVQLVERLIEKEGQESLRSLEEEDQETYRPLEKENGEPLKSVEEELQLVERLIEKEGQESLGSLEEEDQETYRPLEKENGEPLKSVEEEVQLVERLIEKEGQESLGSLEEEDQETYRPLEKEDQKNQESLRSLDENQDTIMPLESKTQKPLKSLEVEEEQRIVKPLEKVSQGSIGSLEKENVELLGSLEDNDQMTESLLKKGTQESLGSHEDTNQETQDPQRFLEEEGQGIVKQLEKENQSFLGSLEEEQVVKRSLERENHEPLSSVEKKDQMTKSLLEKESQDSGKSLEEDQEAFRSLGKEDPESLQSLEEQDQEIQRYLQQETQQILGTLGSAQMASKLPENVGPELLKSLGNDQEIVRSLEEQNQESLVSLKETSVETVKSSEIENTEPLKNAEEDLEIINSIEAQESLWSTEVTRETTKPLEKEIQESLGFVDGNQEMLRPLDRENQELRSLGKWHLETVDSSEGMEEGRQRLEVEAVLETEEHQELLGSLEEGEQGLPGCVNQQGWEDMAVEHAAADQGPTLGRAGVESEDEAELPLSGQGEKKEGAEERERQLDAMGEAWSLEISEPQEQRVPSEEGSPGALQDLEGQPEQVGALEVPVGEGIPEVTEPLLQDEDIAQTGEQDSIEVTLGSENATRAELVLEQEVVGLGGPTHLAREEANHPSLGEESVEAKIAQDLEGSGKEPTEAGALESESSELPRASSDTLESKGCRESEPVVGWAVEEASVETSDHEGSGSPQPRPSETEGDEGTQAALAPPDPKLVEPCSPTPILEDACEQQPQADGIQEAGWQLEGGSEALERVEDEQEFGLGEIPEGLQDWEESREESEADELGETLPDSTPLGLYLRSPTSPKWDLAGEQRLSPQGEARKEGWGPAVLSNPSGEEEQGHDSDLSSEEFEDLGTEVSLLPGLPKEVPPVPEPECWDQGGESDGFADEEESGEEGEEGTESGAQWWGPGSSGGGFKVQHITQRGDLLEHESVGVSGPWDDDLRGATANISVTGLETESQDSAEPSGSEGSESVSSEGEDQVPDHLGAPQGVTNMVPVGGDTFGISGQGPRLESEHMNGRMENGLEQSEGQGVLDGHQDQEYPSQEQEVGALKAPLVGSAVHQGPSQSLEFPLSGVDGDSWSSGED", "length": 1855, "header": "tr|A0A9J7KCD4-1|A0A9J7KCD4_CRIGR Isoform 1 of Nestin OS=Cricetulus griseus OX=10029 GN=Nes PE=3 SV=1 CANONICAL=A0A9J7KCD4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1491, "start_aa": "Thr", "end_pos": 1491, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1491", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761741", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761741", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD4" } ], "pmid": "" }, { "name": "positive regulation of intermediate filament depolymerization", "id": "GO:0030844", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030844", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "intermediate filament", "id": "GO:0005882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "intermediate filament binding", "id": "GO:0019215", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019215", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD4" } ], "pmid": "" }, { "name": "CCR5 chemokine receptor binding", "id": "GO:0031730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031730", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1356, "end_pos": 1358, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1718, "end_pos": 1720, "annotation": "n_glycosylation_sequon" }, { "start_pos": 956, "end_pos": 958, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7KCD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD4" }, { "id": "PS51842", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51842" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IF rod", "eco_id": "ECO_0000259", "start_pos": 8, "end_pos": 314, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1491 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1356, "end_pos": 1358 }, { "start_pos": 1718, "end_pos": 1720 }, { "start_pos": 956, "end_pos": 958 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7KCD7-1", "uniprot_ac": "A0A9J7KCD7", "uniprot_id": "A0A9J7KCD7_CRIGR", "mass": { "chemical_mass": 65495.0, "monoisotopic_mass": 65495.0 }, "refseq": { "ac": "XP_035308941", "name": "albumin isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308941" }, "gene_names": [ { "name": "Alb", "type": "recommended", "evidence": [ { "id": "A0A9J7KCD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD7" } ] }, { "name": "Alb", "type": "synonym", "evidence": [ { "id": "XP_035308941", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308941" } ] } ], "protein_names": [ { "name": "Albumin", "type": "recommended", "evidence": [ { "id": "A0A9J7KCD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD7/entry#names_and_taxonomy" } ] }, { "name": "albumin isoform X3", "type": "synonym", "evidence": [ { "id": "XP_035308941", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308941" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: incomplete on the amino end.", "evidence": [ { "database": "RefSeq", "id": "XP_035308941", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308941" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCD7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Alb", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD7", "locus": {} } ], "crossref": [ { "id": "A0A9J7KCD7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7KCD7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00015", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00015", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100768954", "url": "https://www.ncbi.nlm.nih.gov/gene/100768954", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000264", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000264", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014760", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014760", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020857", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020857", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020858", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020858", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021177", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021177", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768954", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768954", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KCD7", "url": "https://www.orthodb.org/?gene=A0A9J7KCD7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11385", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11385", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11385:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11385:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00273", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00273", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035308941", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308941", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KCD7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KCD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "PVPTDKSEIAHRFKDLGEQHFKGLVLIAFSQYLQKCPYEEHVKLVNEVTDFAKTCVADESAENCGKSLHTLFGDKLCAIPNLRDSYGELADCCAKQEPERNQCFLKHKDDHPNLPPFVRPDPEVMCTSFQENAATFMGHYLHEVARRHPYFYAPELLYYAEKYSAIMTECCGESDKAACLTPKIDALKEKALASSVHQRLKCSSLERFGQRAFKAWAVARLSQKFPKADFAEITKLATDLTKVNEECCHGDLLECADDRAELAKYMCENQASISSKLQACCDKPVLKKSHCLAEVENDELPADLPSLAADFVEDKEVCKNYAEAKDVFLGTFLYEQARRHPDYSIALLLRLAKKYEATLEKCCAEADPPACYGKVLDEFQPLVEEPKNLVKANCDLFEKLGEYGFQNALLVRYTQKAPQVSTPTLVEAAQNLGKVGTKCCVLPEAQRLPCVEDYLSAILNRVCVLHEKTPVSEQVTKCCTGSVVERRPCFSALPVDETYVPKEFKAETFTFHADICTLPEKEKQTKKQTALAELVKHKPKATSDQLKTVMGEFAAFLDKCCKADDKEACFSEDGPKLVASSQAALA", "length": 586, "header": "tr|A0A9J7KCD7-1|A0A9J7KCD7_CRIGR Isoform 1 of Albumin OS=Cricetulus griseus OX=10029 GN=Alb PE=4 SV=1 CANONICAL=A0A9J7KCD7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KCD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD7/entry#A0A9J7KCD7-1", "sequence": { "sequence": "PVPTDKSEIAHRFKDLGEQHFKGLVLIAFSQYLQKCPYEEHVKLVNEVTDFAKTCVADESAENCGKSLHTLFGDKLCAIPNLRDSYGELADCCAKQEPERNQCFLKHKDDHPNLPPFVRPDPEVMCTSFQENAATFMGHYLHEVARRHPYFYAPELLYYAEKYSAIMTECCGESDKAACLTPKIDALKEKALASSVHQRLKCSSLERFGQRAFKAWAVARLSQKFPKADFAEITKLATDLTKVNEECCHGDLLECADDRAELAKYMCENQASISSKLQACCDKPVLKKSHCLAEVENDELPADLPSLAADFVEDKEVCKNYAEAKDVFLGTFLYEQARRHPDYSIALLLRLAKKYEATLEKCCAEADPPACYGKVLDEFQPLVEEPKNLVKANCDLFEKLGEYGFQNALLVRYTQKAPQVSTPTLVEAAQNLGKVGTKCCVLPEAQRLPCVEDYLSAILNRVCVLHEKTPVSEQVTKCCTGSVVERRPCFSALPVDETYVPKEFKAETFTFHADICTLPEKEKQTKKQTALAELVKHKPKATSDQLKTVMGEFAAFLDKCCKADDKEACFSEDGPKLVASSQAALA", "length": 586, "header": "tr|A0A9J7KCD7-1|A0A9J7KCD7_CRIGR Isoform 1 of Albumin OS=Cricetulus griseus OX=10029 GN=Alb PE=4 SV=1 CANONICAL=A0A9J7KCD7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCD7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCD7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768954", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768954", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCD7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD7" } ], "pmid": "" }, { "name": "blood microparticle", "id": "GO:0072562", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072562", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCD7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCD7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD7" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCD7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD7" } ], "pmid": "" }, { "name": "enterobactin binding", "id": "GO:1903981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCD7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCD7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], 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"sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7KCE2-1", "uniprot_ac": "A0A9J7KCE2", "uniprot_id": "A0A9J7KCE2_CRIGR", "mass": { "chemical_mass": 62101.0, "monoisotopic_mass": 62101.0 }, "refseq": { "ac": "XP_035305355", "name": "anthrax toxin receptor-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305355" }, "gene_names": [ { "name": "LOC118239343", "type": "recommended", "evidence": [ { "id": "A0A9J7KCE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE2" } ] }, { "name": "LOC118239343", "type": "synonym", "evidence": [ { "id": "XP_035305355", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305355" } ] } ], "protein_names": [ { "name": "Anthrax toxin receptor-like", "type": "synonym", "evidence": [ { "id": "A0A9J7KCE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE2/entry#names_and_taxonomy" } ] }, { "name": "anthrax toxin receptor-like", "type": "synonym", "evidence": [ { "id": "XP_035305355", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305355" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 19% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613589.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305355", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305355" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCE2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC118239343", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE2", "locus": {} } ], "crossref": [ { "id": "A0A9J7KCE2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7KCE2", "database": "AlphaFoldDB", "categories": [] }, { "id": "118239343", "url": "https://www.ncbi.nlm.nih.gov/gene/118239343", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008400", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008400", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:118239343", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:118239343", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KCE2", "url": "https://www.orthodb.org/?gene=A0A9J7KCE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16059", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16059", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16059:SF30", "url": 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"MLGSCPQVPHSVLFLFALLPSLLSTGNFLYQYPDREYYPGLGLGSRNFHHHEDQNLMHMWHRRNSKLKPCQATPDIYFVLDKSDRMANAWPHIHKFVSDMVQRLSNQDLRVSIITFSCKGTVILPITGDREEILKGLERLKYSIPAGHEHLYRGLWKANTEIKKANSGGVQRPSMIISLLNSPLDDDNYKYSLAEADDARKMGASVFTVGVGHSEKSQIIGLADKPENAFPDRKSEHLNDLISPIASHACPSLKSTDTPIICIRESKPVVLRGYGFDFVMRKEEIICRFYLSDIDNSFRDVKPINFTKNTVTCPGPIVELPGKVIYVLLSLDNGKNFLNNNVFVASKLCGAVLHTTTTTTSRPTTTTTTTTTTTTTTPSTTTTTPTTTTTTTPTTTTTTPTTTTLPTTTESPTTIPTTPLVTEELKPSIDKFIFAPILLAMLLTLSLIGCFWQLCCLPPVEELPPPKPQPQPRQKKQPSAPVSPPAPAPAPAPVNPPPIVIVCCCTCGGLCVRRDAEGNVIVHNFNPLGCHQLPLMWPHSDDQTVSDLMESVYALLSIEVLRT", "length": 563, "header": "tr|A0A9J7KCE2-1|A0A9J7KCE2_CRIGR Isoform 1 of Anthrax toxin receptor-like OS=Cricetulus griseus OX=10029 GN=LOC118239343 PE=3 SV=1 CANONICAL=A0A9J7KCE2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KCE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE2/entry#A0A9J7KCE2-1", "sequence": { "sequence": "MLGSCPQVPHSVLFLFALLPSLLSTGNFLYQYPDREYYPGLGLGSRNFHHHEDQNLMHMWHRRNSKLKPCQATPDIYFVLDKSDRMANAWPHIHKFVSDMVQRLSNQDLRVSIITFSCKGTVILPITGDREEILKGLERLKYSIPAGHEHLYRGLWKANTEIKKANSGGVQRPSMIISLLNSPLDDDNYKYSLAEADDARKMGASVFTVGVGHSEKSQIIGLADKPENAFPDRKSEHLNDLISPIASHACPSLKSTDTPIICIRESKPVVLRGYGFDFVMRKEEIICRFYLSDIDNSFRDVKPINFTKNTVTCPGPIVELPGKVIYVLLSLDNGKNFLNNNVFVASKLCGAVLHTTTTTTSRPTTTTTTTTTTTTTTPSTTTTTPTTTTTTTPTTTTTTPTTTTLPTTTESPTTIPTTPLVTEELKPSIDKFIFAPILLAMLLTLSLIGCFWQLCCLPPVEELPPPKPQPQPRQKKQPSAPVSPPAPAPAPAPVNPPPIVIVCCCTCGGLCVRRDAEGNVIVHNFNPLGCHQLPLMWPHSDDQTVSDLMESVYALLSIEVLRT", "length": 563, "header": "tr|A0A9J7KCE2-1|A0A9J7KCE2_CRIGR Isoform 1 of Anthrax toxin receptor-like OS=Cricetulus griseus OX=10029 GN=LOC118239343 PE=3 SV=1 CANONICAL=A0A9J7KCE2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 73, "start_aa": "Thr", "end_pos": 73, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr73", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCE2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCE2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:118239343", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:118239343", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCE2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE2" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCE2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCE2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE2" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCE2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7KCE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE2" }, { "id": "PS50234", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50234" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFA", "eco_id": "ECO_0000259", "start_pos": 75, "end_pos": 245, "start_aa": "Asp", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 73 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 305, "end_pos": 307 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7KCE3-1", "uniprot_ac": "A0A9J7KCE3", "uniprot_id": "A0A9J7KCE3_CRIGR", "mass": { "chemical_mass": 105534.0, "monoisotopic_mass": 105534.0 }, "refseq": { "ac": "XP_035304688", "name": "neural cell adhesion molecule L1-like protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304688" }, "gene_names": [ { "name": "Chl1", "type": "recommended", "evidence": [ { "id": "A0A9J7KCE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE3" } ] }, { "name": "Chl1", "type": "synonym", "evidence": [ { "id": "XP_035304688", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304688" } ] } ], "protein_names": [ { "name": "Neural cell adhesion molecule L1-like protein", "type": "synonym", "evidence": [ { "id": "A0A9J7KCE3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE3/entry#names_and_taxonomy" } ] }, { "name": "neural cell adhesion molecule L1-like protein", "type": "synonym", "evidence": [ { "id": "XP_035304688", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304688" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304688", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304688" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCE3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Chl1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE3", "locus": {} } ], "crossref": [ { "id": "A0A9J7KCE3", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7KCE3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04978", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04978", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100760694", "url": "https://www.ncbi.nlm.nih.gov/gene/100760694", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026966", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026966", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760694", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760694", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KCE3", "url": "https://www.orthodb.org/?gene=A0A9J7KCE3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12231", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12231", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12231:SF257", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12231:SF257", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13882", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13882", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13895", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13895", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304688", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304688", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KCE3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KCE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCSALGQKPTPQVEWSKPGSELPKGRETKENYGKTLKIENISYHDKGNYRCTASNLLGKASHDFHIIVQEPPRWKKKPQSAVYSTGSSGILLCEAEGEPQPTIKWRVNGFPIENHPFPGDVMFPREISFTNLQPNHTAVYQCEASNIHGTILASANIDVVDVVPLIKTKNEENYATVLGYSAFLHCEYFASPKATVIWEVADEAHPLEGSRYHTHENGTLEIYRTTEEDAGSYSCWVDNAMGKAVITANLDIRNATKLKVSPKNPRIPKSHMLELHCESQCDSHLKHTLKLSWSKDGETFDINGTEDGRIVIDGANLTISNISVEDQGIYSCSAQTALDSISEKTQVTVLGVPDPPGSLLLSERQNRSVRLSWEAGDDHNSNISEYIIEFEGNREEPGKWQELTRIPGEETEAVLSLAPYVRYQFRVIAVNEVGRSYPSQPSDHHETPPAAPDKNPQNIRVQASQPKEMIIKWEPLKSMEQNGPGLEYRVSWKPQGAPEEWEEETVTNHTLRVMTPTVYAPYDVQVQAINQLGSGPEPQPVTLYSGEDYPSTAPVIHGVDVMNSTLVKVTWSSIPKETVHGLLRGYQINWWKTKSLLDGRTHPKEVNILRFSGQRNSGMVPSLDAFSEYHLTVLAYNSKGAGPESEAYIFQTPEGVPEQPSFLKVIKVDKDTATLSWGLPKKLNGNLTGYLLQYQIINDTYEIGELNEINVTTPSKSSWHLSNLNATTKYKFYLKACTSKGCGKPISEESATLGEGSKGIRKITEGVNLTQKIHPVEVLVPGAEHIVHLMTKNWGDNDSIFQDVIETRGREYAGLYDDISTQGWFIGLMCAIALLTLILLTICFVKRNRGGKYSVKEKEDLHPDPEVQSAKDETFGEYSDSDEKPLKGSLRSLNRNMQPTESADSLVEYGEGDHSIFNEDGSFIGAYTGAKEKGSVESNGSSTATFPLRA", "length": 950, "header": "tr|A0A9J7KCE3-1|A0A9J7KCE3_CRIGR Isoform 1 of Neural cell adhesion molecule L1-like protein OS=Cricetulus griseus OX=10029 GN=Chl1 PE=3 SV=1 CANONICAL=A0A9J7KCE3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KCE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE3/entry#A0A9J7KCE3-1", "sequence": { "sequence": "MCSALGQKPTPQVEWSKPGSELPKGRETKENYGKTLKIENISYHDKGNYRCTASNLLGKASHDFHIIVQEPPRWKKKPQSAVYSTGSSGILLCEAEGEPQPTIKWRVNGFPIENHPFPGDVMFPREISFTNLQPNHTAVYQCEASNIHGTILASANIDVVDVVPLIKTKNEENYATVLGYSAFLHCEYFASPKATVIWEVADEAHPLEGSRYHTHENGTLEIYRTTEEDAGSYSCWVDNAMGKAVITANLDIRNATKLKVSPKNPRIPKSHMLELHCESQCDSHLKHTLKLSWSKDGETFDINGTEDGRIVIDGANLTISNISVEDQGIYSCSAQTALDSISEKTQVTVLGVPDPPGSLLLSERQNRSVRLSWEAGDDHNSNISEYIIEFEGNREEPGKWQELTRIPGEETEAVLSLAPYVRYQFRVIAVNEVGRSYPSQPSDHHETPPAAPDKNPQNIRVQASQPKEMIIKWEPLKSMEQNGPGLEYRVSWKPQGAPEEWEEETVTNHTLRVMTPTVYAPYDVQVQAINQLGSGPEPQPVTLYSGEDYPSTAPVIHGVDVMNSTLVKVTWSSIPKETVHGLLRGYQINWWKTKSLLDGRTHPKEVNILRFSGQRNSGMVPSLDAFSEYHLTVLAYNSKGAGPESEAYIFQTPEGVPEQPSFLKVIKVDKDTATLSWGLPKKLNGNLTGYLLQYQIINDTYEIGELNEINVTTPSKSSWHLSNLNATTKYKFYLKACTSKGCGKPISEESATLGEGSKGIRKITEGVNLTQKIHPVEVLVPGAEHIVHLMTKNWGDNDSIFQDVIETRGREYAGLYDDISTQGWFIGLMCAIALLTLILLTICFVKRNRGGKYSVKEKEDLHPDPEVQSAKDETFGEYSDSDEKPLKGSLRSLNRNMQPTESADSLVEYGEGDHSIFNEDGSFIGAYTGAKEKGSVESNGSSTATFPLRA", "length": 950, "header": "tr|A0A9J7KCE3-1|A0A9J7KCE3_CRIGR Isoform 1 of Neural cell adhesion molecule L1-like protein OS=Cricetulus griseus OX=10029 GN=Chl1 PE=3 SV=1 CANONICAL=A0A9J7KCE3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCE3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760694", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760694", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCE3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE3" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCE3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCE3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCE3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" }, { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" }, { "start_pos": 316, "end_pos": 318, "annotation": "n_glycosylation_sequon" }, { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" }, { "start_pos": 366, "end_pos": 368, "annotation": "n_glycosylation_sequon" }, { "start_pos": 382, "end_pos": 384, 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"uniprot_ac": "A0A9J7KCF2", "uniprot_id": "A0A9J7KCF2_CRIGR", "mass": { "chemical_mass": 97975.0, "monoisotopic_mass": 97975.0 }, "refseq": { "ac": "XP_035308997", "name": "LOW QUALITY PROTEIN: nuclear GTPase SLIP-GC", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308997" }, "gene_names": [ { "name": "Nuggc", "type": "recommended", "evidence": [ { "id": "A0A9J7KCF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCF2" } ] }, { "name": "Nuggc", "type": "synonym", "evidence": [ { "id": "XP_035308997", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308997" } ] } ], "protein_names": [ { "name": "Nuclear GTPase SLIP-GC", "type": "recommended", "evidence": [ { "id": "A0A9J7KCF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCF2/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: nuclear GTPase SLIP-GC", "type": "synonym", "evidence": [ { "id": "XP_035308997", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308997" } ] }, { "name": "Speckled-like pattern in the germinal center", "type": "synonym", "evidence": [ { "id": "A0A9J7KCF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCF2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 7% of CDS bases internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035308997", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308997" } ] }, { "annotation": "Nuclear GTPase found in germinal center B-cells, where it may inhibit function of the activation-induced cytidine deaminase AICDA. Reduces somatic hypermutation in B-cells which may enhance genome stability.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCF2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCF2#function" }, { "database": "UniProtKB", "id": "ARBA00054147", "url": "https://www.uniprot.org/uniprotkb/ARBA00054147#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCF2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCF2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Nuggc", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCF2", "locus": {} } ], "crossref": [ { "id": "cd00882", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00882", "database": "CDD", "categories": [ "Protein Classification" ] }, { 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"PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47308:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47308:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00350", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00350", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035308997", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308997", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KCF2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KCF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCF2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEGPTHLHGTIPEQVGLDCVIQVAEWEPGSKPSCTLGYLGTGPLFLLSWIHLDNSYPQRKCAVAECXNLFGKEKWPIDCDLFKEPVKKRRRSHRDQQFQAFPSAEQSALKEYEKLESRTRRVLSNTYQKMIQSVFLDDSIPSGLKYLINRLLALIEKPPLEPIYVGFLGSTGAGKSSLINALIQQAMFLPVSGESICTSCIVQVSSGCCEQYEAKIHLLSDQEWKAELKDLTTLLHRAAGPKGEEVDLWTRDDAAEEAAQKLQMLYGWGAERRPYEDLLRTKLRGRIPTSRTITLKAEEAGELSVKLDPYIRTQRGDWDGESAETQIWPLIKYVEVILPKSALIPEGVVLVDIPGTGDFNSKRDEMWKKTIDKCSVIWVVSDVERVSGGKAHEDLLNESIKACQRGFCKDIALVVTKTDKLHLWEYLRERKMGNQAIQSQREAVLQRNEIIKLQRNRILKEKLKRKLPADSKLLEASDLVYTVSAHEYWQQALLTEEESEIPKLREYIRKRLLDKKRRLVTKYVTEAFGLLLLTDTFNSEESLLTEHLNMGGLRRFVEEKMELLEKSIEQCFSRMEQPLQAGVQVARASYRRILGTFLVRSRGNQGFHQTLKAVCLKNGVYASRTLARIDLNGALSQPIYDQIDPVFGGIFRDGKPTGSALMLHIDAFKHSLEERMAEIGIRNGWKYDGYKRGFLIQEISAILGGLESHILRRKRRIYESVTSSIQNDLKPCYEEAAQITGKKACERMKDIIRRGVERQVAEGMFERAQERMWHQFRQLKHGITEKVKGSITTMLTLASPQGDGLYKELADVRSEQKEMEKLHRSLREVAENAQLRRGMQDFLLRMSPSKAGPHGTKL", "length": 859, "header": "tr|A0A9J7KCF2-1|A0A9J7KCF2_CRIGR Isoform 1 of Nuclear GTPase SLIP-GC OS=Cricetulus griseus OX=10029 GN=Nuggc 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"UniProtKB", "id": "A0A9J7KCJ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCJ9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "basolateral plasma membrane", "id": "GO:0016323", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016323", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCJ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCJ9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "bile acid transmembrane transporter activity", "id": "GO:0015125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015125", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCJ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCJ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 281, "end_pos": 283, 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"evidence": [ { "id": "A0A9J7KDU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDU2/entry#names_and_taxonomy" } ] }, { "name": "thrombospondin type-1 domain-containing protein 7A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035306440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306440" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035306440", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306440" } ] }, { "annotation": "Plays a role in actin cytoskeleton rearrangement.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCK2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCK2#function" }, { "database": "UniProtKB", "id": "ARBA00055483", "url": "https://www.uniprot.org/uniprotkb/ARBA00055483#function" }, { "database": "UniProtKB", "id": "A0A9J7KDU2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDU2#function" }, { "database": "UniProtKB", "id": "A0A8C2MWB8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWB8#function" }, { "database": "UniProtKB", "id": "A0A9J7J360", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J360#function" } ] }, { "annotation": "The soluble form promotes endothelial cell migration and filopodia formation during sprouting angiogenesis via a FAK-dependent mechanism.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCK2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCK2#function" }, { "database": "UniProtKB", "id": "ARBA00056892", "url": "https://www.uniprot.org/uniprotkb/ARBA00056892#function" }, { "database": "UniProtKB", "id": "A0A9J7KDU2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDU2#function" }, { "database": "UniProtKB", "id": "A0A8C2MWB8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWB8#function" }, { "database": "UniProtKB", "id": "A0A9J7J360", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J360#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDU2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDU2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Thsd7a", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDU2", "locus": {} } ], "crossref": [ { "id": "100763919", "url": "https://www.ncbi.nlm.nih.gov/gene/100763919", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044004", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044004", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051418", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051418", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056991", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056991", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763919", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763919", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GRDCMDP", "url": "https://omabrowser.org/oma/group/GRDCMDP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MWB8", "url": "https://www.orthodb.org/?gene=A0A8C2MWB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7J360", "url": "https://www.orthodb.org/?gene=A0A9J7J360", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7KDU2", "url": "https://www.orthodb.org/?gene=A0A9J7KDU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11311", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11311", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11311:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11311:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19030", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19030", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23308", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23308", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035306440", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306440", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MWB8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MWB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MWB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J360", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J360", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J360-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J360-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KCK2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KCK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCK2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KDU2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KDU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDU2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGLRAGRLASRSRGVLQLLRLPVLLLLLLSSGARGAAAQGDAEVPTLYLWKTGPWGRCMGDDCGPGGIQTRAVWCAHVEGWTTLHTNCKQSGRPSNQQNCFKVCDWHKELYDWRLGPWNQCQPVNSKSLEKARECVKGEEGIQVREISCIQKDQDILAEDIICEYFEPKPLLEQACLIPCQQDCIVSEFSAWSECSRTCGSGLQHRTRHVVAPPQFGGSGCPNLTEFQVCQSNPCEAEESMYSLQVGPWSACSVPHSRQARQARRRVKNKERERDRGKAVKDPEARELIKKKRNRNRQNRQENRYWDIQIGYQTRDVMCTNKTGQAADLSFCQQEKLPMTFQSCVITKECQVSEWLEWSPCSKTCHDVTSPTGTRVRTRTIRQLPIGSEKECPELEEKEPCLSQGDGAVLCATYGWRTTEWTECHVDPLLSQQDKRRANQTALCGGGIQTREVYCTQTNDNLLSHLSTQKDKEESDYHSTSKFNGTPLLSITFEITASKPVDSKLCSVPVPNTTQLCHIPCPVECEVSPWSAWGPCTYENCNDQQGRKGFKLRKRRITNEPTGGSGATGNCPHLLEAIPCEEPSCYDWKAVRLGDCEPDNGKACGPGTQVQEVVCINSDGEEVDRQLCRDAIFPIPVACDAPCPKDCVLSAWSTWSSCSHTCSGKTTEGKQIRARSILAYAGEEGGVRCPNSSALQEVRSCNEHPCTVYHWQTGPWGQCIEDTSVSSFNTSTTWNGEASCSVGMQTRKVICVRVNVGQVGPKKCPESLRPETVRPCLLPCRKDCIVTSYSDWTPCPSSCREGDSGPRKQSRHRVIIQLPANGGRDCSDQLYEEKACEAPPMCHSYRWKTHKWRRCQLVPWSVQQDFPGAQEGCGPGRQARAITCRKQDGGQASIQECLQYAGPVPALTQACQIPCQDDCQFTSWSKFSSCNGDCGAVRTRKRAIVGKSKKKEKCKNSHLYPLIETQYCPCDKYNAQPVGNWSDCILPEGKAEVLLGMRVQGDSKECGQGYRYQAMACYDQNGRLVETSRCNSHGYIEEACIIPCPSDCKLSEWSNWSRCSKSCGSGVKVRSKWLREKPYNGGRPCPKLDHVNQAQVYEVVPCHSDCNQYIWVTEPWSVCKVTFVNMRENCGEGVQTRKVRCMQNTADGPSEHVEDYLCDPEDMPLGSRECKLPCPEDCVISEWGPWTQCTLPCNPSGSRQRSAEPIRQPADEGRACPDAVEKEPCNLNKNCYHYDYNVTDWSTCQLSEKAVCGNGIKTRMLDCVRSDGKSVDLKYCEELGLEKNWQMNMSCMVECPLNCQLSDWSSWSECSQTCGLTGKMIRRRTVTQPFQGDGRPCPSLMEQSKPCPVKPCYRWQYGQWSSCQVQEAQCGEGTRTRNISCVVSDGSADDFSKVVDEELCTDIELIVDGNKQIVLEETCTQPCPGDCYLNDWSPWSLCQLTCVNGEDLGFGGIQVRSRAVIIQELENQHLCPEQMLETKSCDDGQCYEYKWMASAWKGSSRTVWCQRSDGVNVTGGCLVVSQPDADRSCNPPCSQPHSYCSEMKACRCEEGYTEVMSSNSTLEQCTLIPVVVIPTVEDKRGDVKTSRAVHPTQPSTNPAGRGRTWFLQPFGPDGRVKTWVYGVAAGAFVLLVFIVSMIYLACHYETDKLARIQVLKSLTHQPPKGGKLLVGLQLLLEGCF", "length": 1680, "header": "tr|A0A9J7KDU2-1|A0A9J7KDU2_CRIGR Isoform 1 of Thrombospondin type-1 domain-containing protein 7A OS=Cricetulus griseus OX=10029 GN=Thsd7a PE=4 SV=1 CANONICAL=A0A9J7KDU2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MWB8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDU2/entry#A0A8C2MWB8-1", "sequence": { "sequence": "MGLRAGRLASRSRGVLQLLRLPVLLLLLLSSGARGAAAQGDAEVPTLYLWKTGPWGRCMGDDCGPGGIQTRAVWCAHVEGWTTLHTNCKQSGRPSNQQNCFKVCDWHKELYDWRLGPWNQCQPVNSKSLEKARECVKGEEGIQVREISCIQKDQDILAEDIICEYFEPKPLLEQACLIPCQQDCIVSEFSAWSECSRTCGSGLQHRTRHVVAPPQFGGSGCPNLTEFQVCQSNPCEAEESMYSLQVGPWSACSVPHSRQARQARRRVKNKERERDRGKAVKDPEARELIKKKRNRNRQNRQENRYWDIQIGYQTRDVMCTNKTGQAADLSFCQQEKLPMTFQSCVITKECQVSEWLEWSPCSKTCHDVTSPTGTRVRTRTIRQLPIGSEKECPELEEKEPCLSQGDGAVLCATYGWRTTEWTECHVDPLLSQQDKRRANQTALCGGGIQTREVYCTQTNDNLLSHLSTQKDKEASKPVDSKLCSVPVPNTTQLCHIPCPVECEVSPWSAWGPCTYENCNDQQGRKGFKLRKRRITNEPTGGSGATGNCPHLLEAIPCEEPSCYDWKAVRLGDCEPDNGKACGPGTQVQEVVCINSDGEEVDRQLCRDAIFPIPVACDAPCPKDCVLSAWSTWSSCSHTCSGKTTEGKQIRARSILAYAGEEGGVRCPNSSALQEVRSCNEHPCTVYHWQTGPWGQCIEDTSVSSFNTSTTWNGEASCSVGMQTRKVICVRVNVGQVGPKKCPESLRPETVRPCLLPCRKDCIVTSYSDWTPCPSSCREGDSGPRKQSRHRVIIQLPANGGRDCSDQLYEEKACEAPPMCHSYRWKTHKWRRCQLVPWSVQQDFPGAQEGCGPGRQARAITCRKQDGGQASIQECLQYAGPVPALTQACQIPCQDDCQFTSWSKFSSCNGDCGAVRTRKRAIVGKSKKKEKCKNSHLYPLIETQYCPCDKYNAQPVGNWSDCILPEGKAEVLLGMRVQGDSKECGQGYRYQAMACYDQNGRLVETSRCNSHGYIEEACIIPCPSDCKLSEWSNWSRCSKSCGSGVKVRSKWLREKPYNGGRPCPKLDHVNQAQVYEVVPCHSDCNQYIWVTEPWSVCKVTFVNMRENCGEGVQTRKVRCMQNTADGPSEHVEDYLCDPEDMPLGSRECKLPCPEDCVISEWGPWTQCTLPCNPSGSRQRSAEPIRQPADEGRACPDAVEKEPCNLNKNCYHYDYNVTDWSTCQLSEKAVCGNGIKTRMLDCVRSDGKSVDLKYCEELGLEKNWQMNMSCMVECPLNCQLSDWSSWSECSQTCGLTGKMIRRRTVTQPFQGDGRPCPSLMEQSKPCPVKPCYRWQYGQWSSCQVQEAQCGEGTRTRNISCVVSDGSADDFSKVVDEELCTDIELIVDGNKQIVLEETCTQPCPGDCYLNDWSPWSLCQLTCVNGEDLGFGGIQVRSRAVIIQELENQHLCPEQMLETKSCDDGQCYEYKWMASAWKGSSRTVWCQRSDGVNVTGGCLVVSQPDADRSCNPPCSQPHSYCSEMKACRCEEGYTEVMSSNSTLEQCTLIPVVVIPTVEDKRGDVKTSRAVHPTQPSTNPAGRGRTWFLQPFGPDGRVKTWVYGVAAGAFVLLVFIVSMIYLACKKPKKPQRRQNNRLKPLTLAYDGDADM", "length": 1646, "header": "tr|A0A8C2MWB8-1|A0A8C2MWB8_CRIGR Computationally mapped isoform of Thrombospondin type-1 domain-containing protein 7A OS=Cricetulus griseus OX=10029 GN=Thsd7a PE=4 SV=1 CANONICAL=A0A9J7KDU2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J360-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDU2/entry#A0A9J7J360-1", "sequence": { "sequence": "MGLRAGRLASRSRGVLQLLRLPVLLLLLLSSGARGAAAQGDAEVPTLYLWKTGPWGRCMGDDCGPGGIQTRAVWCAHVEGWTTLHTNCKQSGRPSNQQNCFKVCDWHKELYDWRLGPWNQCQPVNSKSLEKARECVKGEEGIQVREISCIQKDQDILAEDIICEYFEPKPLLEQACLIPCQQDCIVSEFSAWSECSRTCGSGLQHRTRHVVAPPQFGGSGCPNLTEFQVCQSNPCEAEESMYSLQVGPWSACSVPHSRQARQARRRVKNKERERDRGKAVKDPEARELIKKKRNRNRQNRQENRYWDIQIGYQTRDVMCTNKTGQAADLSFCQQEKLPMTFQSCVITKECQVSEWLEWSPCSKTCHDVTSPTGTRVRTRTIRQLPIGSEKECPELEEKEPCLSQGDGAVLCATYGWRTTEWTECHVDPLLSQQDKRRANQTALCGGGIQTREVYCTQTNDNLLSHLSTQKDKEESDYHSTSKFNGTPLLSITFEITASKPVDSKLCSVPVPNTTQLCHIPCPVECEVSPWSAWGPCTYENCNDQQGRKGFKLRKRRITNEPTGGSGATGNCPHLLEAIPCEEPSCYDWKAVRLGDCEPDNGKACGPGTQVQEVVCINSDGEEVDRQLCRDAIFPIPVACDAPCPKDCVLSAWSTWSSCSHTCSGKTTEGKQIRARSILAYAGEEGGVRCPNSSALQEVRSCNEHPCTVYHWQTGPWGQCIEDTSVSSFNTSTTWNGEASCSVGMQTRKVICVRVNVGQVGPKKCPESLRPETVRPCLLPCRKDCIVTSYSDWTPCPSSCREGDSGPRKQSRHRVIIQLPANGGRDCSDQLYEEKACEAPPMCHSYRWKTHKWRRCQLVPWSVQQDFPGAQEGCGPGRQARAITCRKQDGGQASIQECLQYAGPVPALTQACQIPCQDDCQFTSWSKFSSCNGDCGAVRTRKRAIVGKSKKKEKCKNSHLYPLIETQYCPCDKYNAQPVGNWSDCILPEGKAEVLLGMRVQGDSKECGQGYRYQAMACYDQNGRLVETSRCNSHGYIEEACIIPCPSDCKLSEWSNWSRCSKSCGSGVKVRSKWLREKPYNGGRPCPKLDHVNQAQVYEVVPCHSDCNQYIWVTEPWSVCKVTFVNMRENCGEGVQTRKVRCMQNTADGPSEHVEDYLCDPEDMPLGSRECKLPCPEDCVISEWGPWTQCTLPCNPSGSRQRSAEPIRQPADEGRACPDAVEKEPCNLNKNCYHYDYNVTDWSTCQLSEKAVCGNGIKTRMLDCVRSDGKSVDLKYCEELGLEKNWQMNMSCMVECPLNCQLSDWSSWSECSQTCGLTGKMIRRRTVTQPFQGDGRPCPSLMEQSKPCPVKPCYRWQYGQWSSCQVQEAQCGEGTRTRNISCVVSDGSADDFSKVVDEELCTDIELIVDGNKQIVLEETCTQPCPGDCYLNDWSPWSLCQLTCVNGEDLGFGGIQVRSRAVIIQELENQHLCPEQMLETKSCDDGQCYEYKWMASAWKGSSRTVWCQRSDGVNVTGGCLVVSQPDADRSCNPPCSQPHSYCSEMKACRCEEGYTEVMSSNSTLEQCTLIPVVVIPTVEDKRGDVKTSRAVHPTQPSTNPAGRGRTWFLQPFGPDGRVKTWVYGVAAGAFVLLVFIVSMIYLACKKPKKPQRRQNNRLKPLTLAYDGDADM", "length": 1669, "header": "tr|A0A9J7J360-1|A0A9J7J360_CRIGR Computationally mapped isoform of Thrombospondin type-1 domain-containing protein 7A OS=Cricetulus griseus OX=10029 GN=Thsd7a PE=4 SV=1 CANONICAL=A0A9J7KDU2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KCK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDU2/entry#A0A9J7KCK2-1", "sequence": { "sequence": "MGLRAGRLASRSRGVLQLLRLPVLLLLLLSSGARGAAAQGDAEVPTLYLWKTGPWGRCMGDDCGPGGIQTRAVWCAHVEGWTTLHTNCKQSGRPSNQQNCFKVCDWHKELYDWRLGPWNQCQPVNSKSLEKARECVKGEEGIQVREISCIQKDQDILAEDIICEYFEPKPLLEQACLIPCQQDCIVSEFSAWSECSRTCGSGLQHRTRHVVAPPQFGGSGCPNLTEFQVCQSNPCEAEESMYSLQVGPWSACSVPHSRQARQARRRVKNKERERDRGKAVKDPEARELIKKKRNRNRQNRQENRYWDIQIGYQTRDVMCTNKTGQAADLSFCQQEKLPMTFQSCVITKECQVSEWLEWSPCSKTCHDVTSPTGTRVRTRTIRQLPIGSEKECPELEEKEPCLSQGDGAVLCATYGWRTTEWTECHVDPLLSQQDKRRANQTALCGGGIQTREVYCTQTNDNLLSHLSTQKDKEASKPVDSKLCSVPVPNTTQLCHIPCPVECEVSPWSAWGPCTYENCNDQQGRKGFKLRKRRITNEPTGGSGATGNCPHLLEAIPCEEPSCYDWKAVRLGDCEPDNGKACGPGTQVQEVVCINSDGEEVDRQLCRDAIFPIPVACDAPCPKDCVLSAWSTWSSCSHTCSGKTTEGKQIRARSILAYAGEEGGVRCPNSSALQEVRSCNEHPCTVYHWQTGPWGQCIEDTSVSSFNTSTTWNGEASCSVGMQTRKVICVRVNVGQVGPKKCPESLRPETVRPCLLPCRKDCIVTSYSDWTPCPSSCREGDSGPRKQSRHRVIIQLPANGGRDCSDQLYEEKACEAPPMCHSYRWKTHKWRRCQLVPWSVQQDFPGAQEGCGPGRQARAITCRKQDGGQASIQECLQYAGPVPALTQACQIPCQDDCQFTSWSKFSSCNGDCGAVRTRKRAIVGKSKKKEKCKNSHLYPLIETQYCPCDKYNAQPVGNWSDCILPEGKAEVLLGMRVQGDSKECGQGYRYQAMACYDQNGRLVETSRCNSHGYIEEACIIPCPSDCKLSEWSNWSRCSKSCGSGVKVRSKWLREKPYNGGRPCPKLDHVNQAQVYEVVPCHSDCNQYIWVTEPWSVCKVTFVNMRENCGEGVQTRKVRCMQNTADGPSEHVEDYLCDPEDMPLGSRECKLPCPEDCVISEWGPWTQCTLPCNPSGSRQRSAEPIRQPADEGRACPDAVEKEPCNLNKNCYHYDYNVTDWSTCQLSEKAVCGNGIKTRMLDCVRSDGKSVDLKYCEELGLEKNWQMNMSCMVECPLNCQLSDWSSWSECSQTCGLTGKMIRRRTVTQPFQGDGRPCPSLMEQSKPCPVKPCYRWQYGQWSSCQVQEAQCGEGTRTRNISCVVSDGSADDFSKVVDEELCTDIELIVDGNKQIVLEETCTQPCPGDCYLNDWSPWSLCQLTCVNGEDLGFGGIQVRSRAVIIQELENQHLCPEQMLETKSCDDGQCYEYKWMASAWKGSSRTVWCQRSDGVNVTGGCLVVSQPDADRSCNPPCSQPHSYCSEMKACRCEEGYTEVMSSNSTLEQCTLIPVVVIPTVEDKRGDVKTSRAVHPTQPSTNPAGRGRTWFLQPFGPDGRVKTWVYGVAAGAFVLLVFIVSMIYLACHYETDKLARIQVLKSLTHQPPKGGKLLVGLQLLLEGCF", "length": 1657, "header": "tr|A0A9J7KCK2-1|A0A9J7KDU2_CRIGR Computationally mapped isoform of Thrombospondin type-1 domain-containing protein 7A OS=Cricetulus griseus OX=10029 GN=Thsd7a PE=4 SV=1 CANONICAL=A0A9J7KDU2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KDU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDU2/entry#A0A9J7KDU2-1", "sequence": { "sequence": "MGLRAGRLASRSRGVLQLLRLPVLLLLLLSSGARGAAAQGDAEVPTLYLWKTGPWGRCMGDDCGPGGIQTRAVWCAHVEGWTTLHTNCKQSGRPSNQQNCFKVCDWHKELYDWRLGPWNQCQPVNSKSLEKARECVKGEEGIQVREISCIQKDQDILAEDIICEYFEPKPLLEQACLIPCQQDCIVSEFSAWSECSRTCGSGLQHRTRHVVAPPQFGGSGCPNLTEFQVCQSNPCEAEESMYSLQVGPWSACSVPHSRQARQARRRVKNKERERDRGKAVKDPEARELIKKKRNRNRQNRQENRYWDIQIGYQTRDVMCTNKTGQAADLSFCQQEKLPMTFQSCVITKECQVSEWLEWSPCSKTCHDVTSPTGTRVRTRTIRQLPIGSEKECPELEEKEPCLSQGDGAVLCATYGWRTTEWTECHVDPLLSQQDKRRANQTALCGGGIQTREVYCTQTNDNLLSHLSTQKDKEESDYHSTSKFNGTPLLSITFEITASKPVDSKLCSVPVPNTTQLCHIPCPVECEVSPWSAWGPCTYENCNDQQGRKGFKLRKRRITNEPTGGSGATGNCPHLLEAIPCEEPSCYDWKAVRLGDCEPDNGKACGPGTQVQEVVCINSDGEEVDRQLCRDAIFPIPVACDAPCPKDCVLSAWSTWSSCSHTCSGKTTEGKQIRARSILAYAGEEGGVRCPNSSALQEVRSCNEHPCTVYHWQTGPWGQCIEDTSVSSFNTSTTWNGEASCSVGMQTRKVICVRVNVGQVGPKKCPESLRPETVRPCLLPCRKDCIVTSYSDWTPCPSSCREGDSGPRKQSRHRVIIQLPANGGRDCSDQLYEEKACEAPPMCHSYRWKTHKWRRCQLVPWSVQQDFPGAQEGCGPGRQARAITCRKQDGGQASIQECLQYAGPVPALTQACQIPCQDDCQFTSWSKFSSCNGDCGAVRTRKRAIVGKSKKKEKCKNSHLYPLIETQYCPCDKYNAQPVGNWSDCILPEGKAEVLLGMRVQGDSKECGQGYRYQAMACYDQNGRLVETSRCNSHGYIEEACIIPCPSDCKLSEWSNWSRCSKSCGSGVKVRSKWLREKPYNGGRPCPKLDHVNQAQVYEVVPCHSDCNQYIWVTEPWSVCKVTFVNMRENCGEGVQTRKVRCMQNTADGPSEHVEDYLCDPEDMPLGSRECKLPCPEDCVISEWGPWTQCTLPCNPSGSRQRSAEPIRQPADEGRACPDAVEKEPCNLNKNCYHYDYNVTDWSTCQLSEKAVCGNGIKTRMLDCVRSDGKSVDLKYCEELGLEKNWQMNMSCMVECPLNCQLSDWSSWSECSQTCGLTGKMIRRRTVTQPFQGDGRPCPSLMEQSKPCPVKPCYRWQYGQWSSCQVQEAQCGEGTRTRNISCVVSDGSADDFSKVVDEELCTDIELIVDGNKQIVLEETCTQPCPGDCYLNDWSPWSLCQLTCVNGEDLGFGGIQVRSRAVIIQELENQHLCPEQMLETKSCDDGQCYEYKWMASAWKGSSRTVWCQRSDGVNVTGGCLVVSQPDADRSCNPPCSQPHSYCSEMKACRCEEGYTEVMSSNSTLEQCTLIPVVVIPTVEDKRGDVKTSRAVHPTQPSTNPAGRGRTWFLQPFGPDGRVKTWVYGVAAGAFVLLVFIVSMIYLACHYETDKLARIQVLKSLTHQPPKGGKLLVGLQLLLEGCF", "length": 1680, "header": "tr|A0A9J7KDU2-1|A0A9J7KDU2_CRIGR Isoform 1 of Thrombospondin type-1 domain-containing protein 7A OS=Cricetulus griseus OX=10029 GN=Thsd7a PE=4 SV=1 CANONICAL=A0A9J7KDU2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCK2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCK2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCK2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCK2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763919", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763919", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XKM6-1", "protein_name": "Thrombospondin type-1 domain-containing protein 7A", "gene_name": "THSD7A", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRAAGGMGLSEGSTAFPRGPGLSTSPARCVGVLVVLLLGNWGARAQSEFQTSSVYLWKTGPWGRCMGDECGPGGIQTRAVWCAHVEGWTTLPTNCKQPERPDNQQSCFRVCDWHKELYDWQIGTWDHCRPVLSRSHEKPQECLRGEDGIQTRDITCIQKSNGVPAEDVICEYFEPKPRQEQACLIPCRQDCIVAEFAPWTECSKTCGSGLQHRTRHVVAPPQFGGSACPNLTEFQVCQSSPCAAEESLYSLNVGPWSVCSVPHSRQIRQARKRGKSKDKEKDREKAVRDPEARELIKKKRNRNRQNRQDNKYWDIQIGYQTRQVTCTHRNGKTAALSFCKQDKLPITFQSCVITKECQVSEWSEWTPCSKTCFDMTTPKGNRTRSRTIKQLPIGSESECPQLEETEQCITQGDGVAPCITYGWRTTEWTECRVDPLLSQQDKRRGNQTALCGGGIQTREMYCVQANENLLSYLNTLKEKEESQSQSKSKASAAPLLSITFEITASRPVDRRLCTGPLPSTSQLCHIPCPTECETSAWSAWGPCTYENCDDPQAKKGFKLRKRRITNEPTGGTGNCPHLLEAIPCEEPSCYDWRIVGLEECVPDNEKPCGPGTQVPIVICVNSDGEEVDRQLCRDAIYPIPVVCEAPCPKDCVLSMWSAWSSCSHTCSGKTTEGKQMRARSILAYAGEGGVQCPNSSALQETRSCNEHSCTVYHWQTGPWGQCIEDASVSAFNSSASWNGEATCSVGMQTRKVICVRVNVGQVGPKKCPENLRPETVRPCLLPCRKDCIVTPFSDWTLCPSSCQEGDVIVKKQSRHRVIIQLPANGGRECPDTLFEEKECEASPICYNYRWKTHKWRRCQLVPWYVRQDSPGAHETCGPGLQARAITCRRQDGGQADISECLKYAGPLPSLTQTCQIPCQDDCQFTNWSKFSSCNGDCGGVRTRKRTLIGKSKKKDKCKNSQLYPLIENQFCPCDKYSAQPVGNWSDCILPEGKVEVLLGMKVQGDIKECGQGYRYQAMACYDQNSRLVETSRCNSHGYIEEACIIPCPSDCKLSEWSNWSRCSKSCGSGVKVRSKWLREKPYNGGRPCPKLDHVNQAQVYEVVPCHSDCSQYIWVTEPWSVCKVTNVDLKENCGEGVQTRKVRCMLNTVDGPSDTVEDYLCDPEEMPLGARKCTLPCPEDCVMSEWGSWSRCSLPCNGSSVRERSSEFLRQPVEGKSCPAATEREVCTLNKNCYHYDYNVTDWSTCQLSEKAVCGNGIKTRMLDCVRSDGKSVDLKYCEELGLEKTWQMNISCVVECPVNCQLSDWSSWSDCSQTCGLTGKMIRRRTINQPFQGDGRPCPSQMEQFKPCPVKPCYQWQYGQWSACKVEDAQCGEGTRVRNISCVVFDGSIEDVGKIVDEEFCGEIEPIIDGNKKMILEETCTVPCPGDCYLKEWSEWSLCQLTCVNGEDLGFGGIQVRSRAVIIQDLENQHLCPEQALETRPCNDGHCYEYKWMASPWKGSSRTVWCQRSDGLNVTGGCLVMRQPDADRSCNPPCSQPHAYCSETRTCSCEDGYTEVMSSDGTLEQCTLIPVVVIPTMEDKKGDVKTSRAVNPTQPSTNLSGRGRTWFLQPFGPDGRLKTWVYGVAAGAFVLLIFIVSMIYLACKKPKKPQRRQNNRLKPLTLAYDGDADM", "length": 1671 }, "evidence": [ { "id": "A0A9J7KDU2", "url": "https://omabrowser.org/oma/group/A0A9J7KDU2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A7MBS7-1", "protein_name": "Thrombospondin type-1 domain-containing protein 7A", "gene_name": "thsd7aa", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGLASRAPGKGGTSAGALASLFRVALLFFGLWDVQTQTVANTRPTYIWQTGPWGRCMGSECGPGGSQSRAVWCAHSEGWTTLHTNCQQSERPSNQQSCFRVCDWHKELYDWQLGAWNQCVPVSMRNAGVPRPAVCTRGEEGIQTREVGCVHKSDGVPAEDAICEYFEPKPRLEQACLIPCPRDCVVSEFSPWTSCSKSCGMGLQNRLRSVLAPPLFGGSACPNLTEFRTCQPGKCEGVESLHSLRVGPWGQCMASPIRQARDTGEARVPKAERKAKRDRQARQERQGKRRKNKEKKELRESKGERVRERVKEKKRMRDPETRELIKKKRTRNRQNRQGLKFWDLQVGYQTREVTCVHRSGSTASISQCTQQTLPVTYQACVISKDCEVSEWSDWSVCSKECYDLNGRKGQRTRTRQVQQFPVGGGAECPELEESEPCSPQGEGIPPCVVYNWRSTEWSDCRVDVLLSQQDRRRSNQTGLCGGGVQTREVYCVQAPSETSSNLGSLKSKDALRPVNSDLCLGVPHNTTQLCHIPCPVECEVSAWSAWGPCTFENCQDQSTKKGFKLRKRKIMNEPTGGTGNCPHLTEAIPCEEPSCYDWLLVKLEECVPDNDKVCGPGTQNPQVQCINSDGEFVDRQLCRDAILPMPVLCEVSCPKDCVLSPWTSWSLCSNTCSGKNSEGKQTRARSILAYNAGDGGVQCPNSSALQEVRSCNDHPCTVYHWQTGPWGQCIEDTSVPSANSSISRAVPGTAVNDAFCSVGMQTRKVICVRVNVGQVPPKKCPESLRPETVRPCLLPCKRDCVVTPYSDWTPCPSICQTGGSVKKKQSRKRIIIQLPANGGQDCPEVLFQEKDCDASSVCPGYRWKTHKWRRCQLVPWSIRQDSPGAQETCGPGLQARAVSCKKLDSGPADVAACLKFAGPMPQLTQSCQLPCQDDCQLTAWSKFSTCAADCVGVRTRKRTLVGKSKKREQCKNTQMYPLSETQYCPCNKYNAQPVGNWSDCILPEGRVEGLLGMKVQGDIKECGQGYRYQAMVCYDQDNRLVETSRCNSHGYIEEACIIPCPSDCKLSEWSNWSRCSKSCGSGVKVRSKWLREKPYNGGRPCPKLDHVNQAQVYEVVPCLSDCSQYVWVAEPWSVWKVSNVDLKENCGEGVQTRKVRCMQNTVDGPSDPVEDYLCDPEEMPLGARESKLPCPEDCVLTDWGSWSRCPLPCNVNSTRQRSASPIRQPSERKQCPSTTEKEICTLNSNCFHYSYNITDWSTCQLSERAVCGVGFKTRMLDCVRSDSKSVDLKFCEELGLEKKWQMNASCVVECPVNCQLSDWSSWSECSHTCGLAGKLWRRRTVIQASQGDGRPCSSQLEQWKPCPVKPCFSWRYSVWSPCKSEGARCGEGLRFRNVSCFVSDGSGKDAGSMVDEELCGDLEQTVDGDKQIILQESCTVPCPGECYLTDWTMWSPCQLSCIGGDDLGFGSVQVRSRAVLAQEPENLLQCPEQEWEARPCTEGQCYDYKWMTGAWRGSSRQVWCQRSDGLNVTGGCQSTTEPVSDRSCDPACDKPRSICTEAGICGCEEGYTEVMTSDGVLDQCTVIPVLEIPTAGDSKADVKTIRALNPTEPTANMPGRAGRTWFLQPFGPDGKLKTWVYGVAAGAFVLLVFIVSMTYLACKKPKKPQRRQMNNRLKPLTLAYDGDADM", "length": 1686 }, "evidence": [ { "id": "A0A9J7KDU2", "url": "https://omabrowser.org/oma/group/A0A9J7KDU2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1MA97-1", "protein_name": "Thrombospondin type-1 domain-containing protein 7A", "gene_name": "Thsd7a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLRAGRLASLSRGVLQLMRLPLLLLLLLSSGARGAAAQGDTEVPTLYLWKTGPWGRCMGDDCGPGGIQTRAVWCAHSEGWTTLHTNCKQAVRPSNQQNCFKVCDWHKELYDWRLGPWNQCQPVISKSLEKARECVKGEEGIQVREITCIQKDKDIPAEDIICEYFEPKPLLEQACLIPCQQDCIVSEFSSWSECSRTCGSGLQHRTRHVVAPPQFGGSGCPNLTEFQVCQSNPCEAEESMYSLQVGPWSACSVPHSRQARQARRRGKNKEREKERGKAVKDPEARELIKKKRNRNRQNRQENRYWDIQIGYQTRDVMCLNRTGKSADLSFCQQERLPMTFQSCVITKECQVSEWSEWSPCSKTCHDVTSPTGTRVRTRTIRQFPIGSEKECPELEEKEPCLSQGDGAVLCATYGWRTTEWTECHVDPLLSQQDKRRANQTALCGGGVQTREIYCIQTNDILLSHINTQKDKEASKPVDSKLCTGPVPNTTQLCHVPCPIECEVSPWSAWGPCTYENCNDQQGKKGFKLRKRRITNEPTGGSGATGNCPHLLEAIPCEEPSCYDWKSVRLGDCEPDNGKACGPGTQVQEVVCINSDGEEVDRQLCRDAIFPIPVACDAPCPKDCVLSAWSTWSSCSHTCSGKTTEGKQIRARSILAYAGEEGGIRCPNSSALQEVRSCNEHPCTVYHWQTGPWGQCIEDTSVSSFNTTTTWTGETSCSVGMQTRKVICVRVNVGQVGPKKCPESLRPETVRPCLLPCRKDCIMTPYSDWTPCPSSCREGDSGARKQSRQRVIIQLPAYGGRECSDPLYEEKACEAPPTCHSYRWKTHKWRRCQLVPWSIQQDVPGAQEGCGPGRQARAITCRKQDGGQASIQECLQYAGPVPALTQACQIPCQDDCQFTSWSKFSSCNGDCGAVRTRKRAIVGKSKKKEKCKNSHLYPLIETQYCPCDKYNAQPVGNWSDCILPEGKAEVLLGVKVQGDNKECGQGYRYQAMACYDQNGRLVETSRCNSHGYIEEACIIPCPSDCKLSEWSNWSRCSKSCGSGVKVRSKWLREKPYNGGRPCPKLDHVNQAQVYEVVPCHSDCNQYIWVTEPWSVCKVTFVDMRDNCGEGVQTRKVRCMQNTADGPSEHVEDYLCDPEDMPLGSRECKLPCPEDCVISEWGPWTQCSLPCNPSGSRQRSADPIRQPADEGRACPDAVEKEPCNLNKNCYRYDYNVTDWSTCQLSEKAVCGNGIKTRMLDCVRSDGKSVDLKYCEELGLEKNWQMNSSCTVECPLNCQLSDWSPWSECSQTCGLTGKMIRRRTVTQPFQGDGRPCPSLMEQSKPCPVKPCYRWQYGQWSPCQVQEAQCGEGTRTRNISCVVSDGSADDFSKAVDEEFCANIELIIDGNKQIVLEETCTQPCPGDCYLNDWSSWSLCQLTCVNGEDLGFGGIQVRSRAVIIQELENQHLCPEQILETKSCDDGQCYEYKWMASAWKGSSRTVWCQRSDGVNVTGGCLVVSQPDADRSCNPPCSQPHSYCSEMKACRCEEGYTEVMSSNSTLEQCTLIPVVVIPTVEDKRDVKTSRAVHPTQPSSNPAGRGRTWFLQPFGPDGRLKTWVYGVAAGAFVLLVFIVSMIYLACKKPKKPQRRQNNRLKPLTLAYDGDADM", "length": 1645 }, "evidence": [ { "id": "A0A9J7KDU2", "url": "https://omabrowser.org/oma/group/A0A9J7KDU2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q69ZU6-1", "protein_name": "Thrombospondin type-1 domain-containing protein 7A", "gene_name": "Thsd7a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLRAGRLASPSRGVLQLLRLPLLLLLLLSSGARGAAAQGDTEVPTLYLWKTGPWGRCMGDDCGPGGIQTRAVWCAHVEGWTTLHTNCKQAVRPSNQQNCFKVCDWHKELYDWRLGTWDRCQPVISKSLEKSRECVKGEEGIQVREIMCIQKDKDIPAEDIICEYFEPKPLLEQACLIPCQKDCIVSEFSPWSECSRTCGSGLQHRTRHVVAPPQYGGSGCPNLTEFQVCQSNPCEEDESLYSLQVGPWSACSVPHTRQARQARRRGKNKEREKERGKAVKDPEARELIKKKRNRNRQNRQENRYWDIQIGYQTRDVTCLNRTGKSADLSFCQQERLPMTFQSCVITKECQVSEWLEWSPCSKTCHDVTSPTGTRVRTRTITQFPIGSEKECPALEEKEPCVSQGDGAVLCATYGWRTTEWTECHVDPLLSQQDKRRANQTALCGGGVQTREIYCIQTNDNMLSHGNTQKDKEASKPVDSKLCTGPVPNTTQLCHVPCPIECEVSPWSAWGPCTYENCNDQQGKKGFKLRKRRITNEPTGGSGATGNCPHLLEAIPCEEPSCYDWKSVRLGDCEPDNGKSCGPGTQVQEVVCINSDGEEVDRQLCRDAIFPIPVACDAPCPKDCVLSAWSSWSSCSHTCSGKTTEGKQTRARSILAYAGEEGGIRCPNISALQEVRSCNEHPCTVYHWQTGPWGQCIEDTSVSSFNTTTTWNGEASCSVGMQTRKVICVRVNVGQVGPKKCPESLRPETVRPCLLPCRKDCVVTPYSDWTPCPSSCREGDSGARKQSRQRVIIQLPANGGKECSDPLYEEKACEAPPTCHSYRWKTHKWRRCQLVPWSIQQDVPGAQEGCGPGRQARAITCRKQDGGQASIQECLQYAGPVPALTQACQIPCQDDCQFTSWSKFSSCNGDCGAVRTRKRAIVGKSKKKEKCKNSHLYPLIETQYCPCDKYNAQPVGNWSDCILPEGKAEVLLGMKVQGDSKECGQGYRYQAMACYDQNGRLVETSRCNSHGYIEEACIIPCPSDCKLSEWSNWSRCSKSCGSGVKVRSKWLREKPYNGGRPCPKLDHVNQAQVYEVVPCHSDCNQYIWVTEPWSVCKVTFVDMRDNCGEGVQTRKVRCMQNTADGPSEHVEDYLCDPEDMPLGSRECKLPCPEDCVISEWGPWTCALPCNPSGSRQRSADPIRQPADEGRACPDAVEKEPCSLNKNCYHYDYNVTDWSTCQLSEKAVCGNGIKTRMLDCVRSDGKSVDLKYCEELGLEKNWPMNTSCTVECPVNCQLSDWSSWSQCSQTCGLTGKMIRKRTVTQPFQGDGRPCPSLMEQSKPCPVKPCYRWQYGQWSPCQVQEAQCGEGTRTRNISCVVSDGSAEDFSKVVDEEFCANTELIIDGNKQIVLEETCTQPCPGDCYLNDWSSWSLCQLTCVNGEDLGFGGIQVRSRAVIIQELENQHLCPEQMLETKSCDDGQCYEYKWVASAWKGSSRTVWCQRSDGINVTGGCLVVSQPDTDRSCNPPCSQPHSYCSEMKTCRCEEGYTEVMSSNSTLEQCTLIPVVVIPTVEDKRGDVKTSRAVHPTQPSINPAGRGRTWFLQPFGPDGRLKTWVYGVAAGAFVLLVFIVSMIYLACKKPKKPQRRQNNRLKPLTLAYDGDADM", "length": 1645 }, "evidence": [ { "id": "A0A9J7KDU2", "url": "https://omabrowser.org/oma/group/A0A9J7KDU2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UPZ6-1", "protein_name": "Thrombospondin type-1 domain-containing protein 7A", "gene_name": "THSD7A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLQARRWASGSRGAAGPRRGVLQLLPLPLPLPLLLLLLLRPGAGRAAAQGEAEAPTLYLWKTGPWGRCMGDECGPGGIQTRAVWCAHVEGWTTLHTNCKQAERPNNQQNCFKVCDWHKELYDWRLGPWNQCQPVISKSLEKPLECIKGEEGIQVREIACIQKDKDIPAEDIICEYFEPKPLLEQACLIPCQQDCIVSEFSAWSECSKTCGSGLQHRTRHVVAPPQFGGSGCPNLTEFQVCQSSPCEAEELRYSLHVGPWSTCSMPHSRQVRQARRRGKNKEREKDRSKGVKDPEARELIKKKRNRNRQNRQENKYWDIQIGYQTREVMCINKTGKAADLSFCQQEKLPMTFQSCVITKECQVSEWSEWSPCSKTCHDMVSPAGTRVRTRTIRQFPIGSEKECPEFEEKEPCLSQGDGVVPCATYGWRTTEWTECRVDPLLSQQDKRRGNQTALCGGGIQTREVYCVQANENLLSQLSTHKNKEASKPMDLKLCTGPIPNTTQLCHIPCPTECEVSPWSAWGPCTYENCNDQQGKKGFKLRKRRITNEPTGGSGVTGNCPHLLEAIPCEEPACYDWKAVRLGNCEPDNGKECGPGTQVQEVVCINSDGEEVDRQLCRDAIFPIPVACDAPCPKDCVLSTWSTWSSCSHTCSGKTTEGKQIRARSILAYAGEEGGIRCPNSSALQEVRSCNEHPCTVYHWQTGPWGQCIEDTSVSSFNTTTTWNGEASCSVGMQTRKVICVRVNVGQVGPKKCPESLRPETVRPCLLPCKKDCIVTPYSDWTSCPSSCKEGDSSIRKQSRHRVIIQLPANGGRDCTDPLYEEKACEAPQACQSYRWKTHKWRRCQLVPWSVQQDSPGAQEGCGPGRQARAITCRKQDGGQAGIHECLQYAGPVPALTQACQIPCQDDCQLTSWSKFSSCNGDCGAVRTRKRTLVGKSKKKEKCKNSHLYPLIETQYCPCDKYNAQPVGNWSDCILPEGKVEVLLGMKVQGDIKECGQGYRYQAMACYDQNGRLVETSRCNSHGYIEEACIIPCPSDCKLSEWSNWSRCSKSCGSGVKVRSKWLREKPYNGGRPCPKLDHVNQAQVYEVVPCHSDCNQYLWVTEPWSICKVTFVNMRENCGEGVQTRKVRCMQNTADGPSEHVEDYLCDPEEMPLGSRVCKLPCPEDCVISEWGPWTQCVLPCNQSSFRQRSADPIRQPADEGRSCPNAVEKEPCNLNKNCYHYDYNVTDWSTCQLSEKAVCGNGIKTRMLDCVRSDGKSVDLKYCEALGLEKNWQMNTSCMVECPVNCQLSDWSPWSECSQTCGLTGKMIRRRTVTQPFQGDGRPCPSLMDQSKPCPVKPCYRWQYGQWSPCQVQEAQCGEGTRTRNISCVVSDGSADDFSKVVDEEFCADIELIIDGNKNMVLEESCSQPCPGDCYLKDWSSWSLCQLTCVNGEDLGFGGIQVRSRPVIIQELENQHLCPEQMLETKSCYDGQCYEYKWMASAWKGSSRTVWCQRSDGINVTGGCLVMSQPDADRSCNPPCSQPHSYCSETKTCHCEEGYTEVMSSNSTLEQCTLIPVVVLPTMEDKRGDVKTSRAVHPTQPSSNPAGRGRTWFLQPFGPDGRLKTWVYGVAAGAFVLLIFIVSMIYLACKKPKKPQRRQNNRLKPLTLAYDGDADM", "length": 1657 }, "evidence": [ { "id": "A0A9J7KDU2", "url": "https://omabrowser.org/oma/group/A0A9J7KDU2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDU2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDU2" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDU2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDU2" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDU2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDU2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDU2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDU2" } ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDU2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDU2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1055, "end_pos": 1057, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1237, "end_pos": 1239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1288, "end_pos": 1290, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1378, "end_pos": 1380, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1512, "end_pos": 1514, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1559, "end_pos": 1561, "annotation": "n_glycosylation_sequon" }, { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" }, { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" }, { "start_pos": 439, "end_pos": 441, "annotation": "n_glycosylation_sequon" }, { "start_pos": 484, "end_pos": 486, "annotation": "n_glycosylation_sequon" }, { "start_pos": 512, "end_pos": 514, "annotation": "n_glycosylation_sequon" }, { "start_pos": 691, "end_pos": 693, "annotation": "n_glycosylation_sequon" }, { "start_pos": 729, "end_pos": 731, "annotation": "n_glycosylation_sequon" }, { "start_pos": 980, "end_pos": 982, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7KDU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDU2" }, { "id": "PF19028", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19028" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Spondin-like TSP1", "eco_id": "ECO_0000259", "start_pos": 184, "end_pos": 235, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7KDU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDU2" }, { "id": "PF23308", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23308" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Thrombospondin type-1", "eco_id": "ECO_0000259", "start_pos": 1531, "end_pos": 1570, "start_aa": "Pro", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1055, "end_pos": 1057 }, { "start_pos": 1237, "end_pos": 1239 }, { "start_pos": 1288, "end_pos": 1290 }, { "start_pos": 1378, "end_pos": 1380 }, { "start_pos": 1512, "end_pos": 1514 }, { "start_pos": 1559, "end_pos": 1561 }, { "start_pos": 223, "end_pos": 225 }, { "start_pos": 321, "end_pos": 323 }, { "start_pos": 439, "end_pos": 441 }, { "start_pos": 484, "end_pos": 486 }, { "start_pos": 512, "end_pos": 514 }, { "start_pos": 691, "end_pos": 693 }, { "start_pos": 729, "end_pos": 731 }, { "start_pos": 980, "end_pos": 982 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7KCL2-1", "uniprot_ac": "A0A9J7KCL2", "uniprot_id": "A0A9J7KCL2_CRIGR", "mass": { "chemical_mass": 17032.0, "monoisotopic_mass": 17032.0 }, "refseq": { "ac": "XP_035306472", "name": "patr class I histocompatibility antigen, A-126 alpha chain-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306472" }, "gene_names": [ { "name": "LOC100758961", "type": "recommended", "evidence": [ { "id": "A0A9J7KCL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCL2" } ] }, { "name": "LOC100758961", "type": "synonym", "evidence": [ { "id": "XP_035306472", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306472" } ] } ], "protein_names": [ { "name": "Patr class I histocompatibility antigen, A-126 alpha chain-like isoform X1", "type": "synonym", "evidence": [ { "id": "A0A9J7KCL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCL2/entry#names_and_taxonomy" } ] }, { "name": "patr class I histocompatibility antigen, A-126 alpha chain-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035306472", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306472" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. 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"length": 1016, "header": "tr|A0A9J7KCM0-1|A0A9J7KCM0_CRIGR Isoform 1 of Contactin-4 OS=Cricetulus griseus OX=10029 GN=Cntn4 PE=3 SV=1 CANONICAL=A0A9J7KCM0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 22% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304940", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304940" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCM5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113837018", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5", "locus": {} } ], "crossref": [ { "id": "A0A9J7KCM5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7KCM5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14337", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14337", "database": "CDD", "categories": [ "Protein 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OS=Cricetulus griseus OX=10029 GN=LOC113837018 PE=4 SV=1 CANONICAL=A0A9J7KCM5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KCM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5/entry#A0A9J7KCM5-1", "sequence": { "sequence": "MAVSGRFLPVNKDLIMEQGREVCYSCEESFMTDDKMMMSVGHGRFSEVKLAFHVPTVTCVAVKVLRMKKKNASLVEVSIMKSLQHPDIIKLFGMVQSRDTTYLMMEHASQGDLRHILELGSLQESEARRLFTQILLAMQYCHVNHIAHRDIKANNILLNCRGNAKLSGFDLAAKVTPGQKLRDFCGTLLYCAPELLLEKAYDGCAADIWSLGVLLFLMVVGRFPFQDSSSEGVRRQILAANVRIPEHVSRDIFNVIVKMLMIKPHRRPTVDQILMCPMIREGKPHSPPMSPQKHPGTVSRGIVSTMTVMGYKSEEITDSLRDQKYNQVMATYPILQHQSPGGDCGLEATNTKKVSVTKEVTITKEAAITQDPTITQEEEDMAHEVTMTLEKTMTKEMTMDDGVSMTQTESITEEETIIKHEDIIREATITMEETVVQLRTLTQERTITQEEAITHGQPEDALTRERTITQEETITKHEDIILEATITMEETVAHLRTLTRERTITQEEAITHGQPEDALTRERTITQEETITHGQPEDAGPASSGNRRRSGWKRAKKIMVNCLRHLCCCCLPPAKRRHDSCKTLAPKTRDPAVTHRSSSEEVQPQLRGL", "length": 609, "header": "tr|A0A9J7KCM5-1|A0A9J7KCM5_CRIGR Isoform 1 of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=LOC113837018 PE=4 SV=1 CANONICAL=A0A9J7KCM5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 176, "start_aa": "Thr", "end_pos": 176, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr176", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCM5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCM5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:113837018", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113837018", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCM5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ], "pmid": "" }, { "name": "tau-protein kinase activity", "id": "GO:0050321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050321", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCM5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCM5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCM5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCM5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRI0-1", "G3GWJ3-1", "G3GYQ3-1", "A0A9J7GY39-1", "G3H3C3-1", "G3HAZ9-1", "G3HLS6-1", "G3HVB0-1", "G3HVN3-1", "G3I7I8-1", "G3ICC3-1", "G3IDN3-1", "G3IN30-1", "Q63980-1", "G3GY19-1", "G3GVI7-1", "G3GWN1-1", "A0A9J7FF35-1", "G3HBI7-1", "A0A9J7H2E9-1", "G3H3S6-1", "G3H8I4-1", "G3HCC1-1", "G3HER3-1", "G3HT38-1", "G3HZH7-1", "G3IFB6-1", "G3IKJ7-1", "G3H5L5-1", "G3IGI9-1", "G3HZ18-1", "G3I472-1", "G3HMY1-1", "G3HZU1-1", "G3I3E2-1", "G3I8T5-1", "G3I0W5-1", "G3IB29-1", "A0A9J7GIM1-1", "G3HEH4-1", "A0A9J7GES8-1", "A0A9J7F0J6-1", "G3HTW4-1", "G3HV08-1", "G3I3Z8-1", "G3I5H0-1", "A0A9J7FDV1-1", "G3GRR1-1", "G3GUA6-1", "G3GX92-1", 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"A0A9J7H540-1", "A0A9J7H949-1", "A0A9J7H3S8-1", "A0A9J7H401-1", "A0A9J7H503-1", "A0A9J7KCN2-1", "A0A9J7H7W6-1", "A0A9J7H8E3-1", "A0A9J7H8W5-1", "A0A9J7GF26-1", "A0A9J7GHK2-1", "A0A9J7GHV2-1", "A0A9J7GK55-1", "A0A9J7GLT3-1", "A0A9J7GMK5-1", "A0A9J7GP29-1", "A0A9J7GQY0-1", "A0A9J7GR05-1", "A0A9J7GRB5-1", "A0A9J7GRC1-1", "A0A8C2M6X8-1", "A0A9J7GTU0-1", "A0A9J7GVC9-1", "A0A9J7H0W8-1", "A0A9J7H1I4-1", "A0A9J7H241-1", "A0A3L7I5Y4-1", "A0A9J7JPF2-1", "A0A9J7JU24-1", "A0A9J7JNT2-1", "A0A9J7JSB5-1", "A0A9J7JTJ0-1", "A0A9J7K3L1-1", "A0A9J7K6R5-1", "A0A9J7KB54-1", "A0A9J7K851-1", "A0A9J7KCM5-1", "A0A9J7HEQ9-1", "A0A9J7J6E9-1", "A0A9J7J728-1", "A0A9J7JA07-1", "A0A3L7HMX8-1", "A0A061HZ27-1", "A0A9J7K7C7-1", "A0A061IJA8-1", "A0A8C2LA64-1", "A0A8C2LE67-1", "A0A8C2LII0-1", "A0A8C2LTD1-1", "A0A8C2M4R2-1", "A0A8C2MC09-1", "A0A8C2MCI5-1", "A0A8C2MP62-1", "A0A8C2N3U2-1", "A0A8C2M4P9-1", "A0A8C2QHS8-1", "A0A8C2QIA1-1", "A0A8C2QMB3-1", "A0A9J7F8T9-1", "A0A9J7FN52-1", "O55076-1", "P68180-1", "A0A061IJW6-1", "A0A3L7HQF4-1", "A0A3L7HRZ8-1", "A0A8C2LI15-1", "A0A8C2M497-1", "A0A8C2MAD7-1", "G3HBD4-1", "P25321-1", "A0A8C2MBP2-1", "A0A9J7JGR2-1", "A0A8C2QLT0-1", "A0A9J7JYC5-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRI0-1", "G3GWJ3-1", "G3GYQ3-1", "A0A9J7GY39-1", "G3H3C3-1", "G3HAZ9-1", "G3HLS6-1", "G3HVB0-1", "G3HVN3-1", "G3I7I8-1", "G3ICC3-1", "G3IDN3-1", "G3IN30-1", "Q63980-1", "G3GY19-1", "G3GVI7-1", "G3GWN1-1", "A0A9J7FF35-1", "G3HBI7-1", "A0A9J7H2E9-1", "G3H3S6-1", "G3H8I4-1", "G3HCC1-1", "G3HER3-1", "G3HT38-1", "G3HZH7-1", "G3IFB6-1", "G3IKJ7-1", "G3H5L5-1", "G3IGI9-1", "G3HZ18-1", "G3I472-1", "G3HMY1-1", "G3HZU1-1", "G3I3E2-1", "G3HX91-1", "G3I8T5-1", "G3I0W5-1", "G3IB29-1", "A0A9J7GIM1-1", "G3HEH4-1", "A0A9J7GES8-1", "A0A9J7F0J6-1", "G3HTW4-1", "G3HV08-1", "G3I3Z8-1", "G3I5H0-1", "A0A9J7FDV1-1", "G3GRR1-1", "G3GUA6-1", "G3GX92-1", "G3HY42-1", "A0A8C2QND0-1", "G3HXQ8-1", "A0A8C2M0A2-1", "A0A9J7K2S5-1", "A0A8C2MMZ5-1", "A0A8C2QH69-1", "A0A8C2QL63-1", "A0A9J7K953-1", "A0A9J7JBH0-1", "A0A9J7FEY2-1", "A0A9J7FGD3-1", "A0A9J7FKM1-1", "A0A9J7JKJ1-1", "A0A9J7G3C1-1", "A0A9J7G180-1", "A0A9J7JTL3-1", "A0A9J7GFS3-1", "A0A9J7GQ42-1", "A0A9J7EZ53-1", "A0A9J7J5Z8-1", "A0A9J7F0G6-1", "A0A9J7FCC7-1", "A0A9J7EVK4-1", "A0A9J7K3S4-1", "A0A9J7GAF4-1", "A0A9J7GBF4-1", "A0A8C2MTI7-1", "A0A9J7J1N3-1", "A0A9J7F4P4-1", "A0A9J7JNU2-1", "A0A9J7H3M5-1", "A0A9J7JJV6-1", "A0A9J7GJE4-1", "A0A8C2LY52-1", "A0A9J7H8U3-1", "A0A9J7F821-1", "A0A8C2N185-1", "A0A9J7KFV8-1", "A0A8C2MQM0-1", "A0A8C2N310-1", "A0A9J7H6V8-1", "A0A9J7H2P9-1", "A0A9J7H4N5-1", "A0A3L7GPC7-1", "A0A9J7J6H1-1", "A0A3L7HV37-1", "A0A8C2LTZ7-1", "A0A9J7K7D8-1", "A0A9J7JXM2-1", "A0A8C2LDU9-1", "A0A8C2LTW4-1", "A0A9J7JAM4-1", "A0A9J7JRJ8-1", "A0A8C2QEB8-1", "A0A3L7HKC4-1", "A0A8C2LI14-1", "A0A8C2QDX9-1", "A0A9J7G1D9-1", "A0A9J7F985-1", "A0A9J7G270-1", "A0A9J7K1H4-1", "A0A8C2MCX3-1", "A0A8C2MEU5-1", "A0A8C2MFN1-1", "A0A8C2MMI4-1", "A0A9J7JAB2-1", "A0A9J7G969-1", "A0A8C2MQ42-1", "A0A8C2MR08-1", "A0A8C2MUQ5-1", "A0A9J7FZA7-1", "A0A8C2N3C9-1", "A0A8C2N6L4-1", "A0A8C2N9X1-1", "A0A8C2QHF9-1", "A0A8C2QI80-1", "A0A8C2QKP7-1", "A0A9J7FFS7-1", "A0A9J7FI14-1", "A0A9J7FJ23-1", "A0A9J7JLH7-1", "A0A8C2MH43-1", "A0A9J7FZ18-1", "A0A9J7G368-1", "A0A9J7G6S5-1", "A0A9J7H2T6-1", "A0A9J7H3N1-1", "A0A9J7H8L4-1", "A0A9J7JIW6-1", "A0A9J7JRI3-1", "A0A061ILI7-1", "A0A061HUS7-1", "A0A061HVM6-1", "A0A061I033-1", "A0A061I8L6-1", "A0A061I9F9-1", "A0A8C2MQS3-1", "A0A9J7F0Y2-1", "A0A9J7EZ49-1", "A0A8C2M6A3-1", "A0A8C2MQL9-1", "A0A8C2LY02-1", "A0A8C2LZT2-1", "A0A8C2M165-1", "A0A8C2M5G2-1", "A0A8C2M3Y9-1", "A0A8C2M5A7-1", "A0A8C2M9B6-1", "A0A8C2MBW2-1", "A0A9J7JYU7-1", "A0A8C2MJ02-1", "A0A8C2ML15-1", "A0A9J7JQD1-1", "A0A8C2MMQ4-1", "A0A8C2MQ73-1", "A0A9J7KE81-1", "A0A9J7JPE2-1", "A0A9J7F773-1", "A0A8C2L7R1-1", "A0A8C2LHE9-1", "A0A3L7I870-1", "A0A3L7IB60-1", "A0A3L7IBX6-1", "A0A3L7ID00-1", "A0A3L7IEL5-1", "A0A3L7IER1-1", "A0A8C2LC89-1", "A0A8C2LCN7-1", "A0A8C2LEI8-1", "A0A8C2LH99-1", "A0A9J7GAB0-1", "A0A8C2LK72-1", "A0A8C2LMC9-1", "A0A8C2LMJ0-1", "A0A9J7JQV6-1", "A0A8C2LPR4-1", "A0A8C2LQB2-1", "A0A8C2LVV5-1", "A0A8C2MYH0-1", "A0A8C2MV78-1", "A0A9J7JHJ2-1", "A0A8C2N0J6-1", "A0A8C2N210-1", "A0A8C2N457-1", "A0A8C2N4W2-1", "A0A8C2N756-1", "A0A8C2QGY5-1", "A0A8C2QJ34-1", "A0A8C2QJA4-1", "A0A9J7KDV7-1", "A0A8C2QNX2-1", "A0A8C2QPB0-1", "A0A9J7EVN3-1", "A0A9J7F0N6-1", "A0A8C2M6E6-1", "A0A9J7F2L0-1", "A0A9J7F3R3-1", "A0A9J7F5B0-1", "A0A8C2LDE5-1", "A0A9J7JB60-1", "A0A9J7F927-1", "A0A9J7F8V5-1", "A0A9J7F8T0-1", "A0A9J7FBT0-1", "A0A9J7FD79-1", "A0A9J7FLY5-1", "A0A9J7K2Q7-1", "A0A3L7I1R2-1", "A0A9J7FYY3-1", "A0A9J7GBI2-1", "A0A9J7FN68-1", "A0A9J7FNF0-1", "A0A9J7FS53-1", "A0A9J7FUL0-1", "A0A9J7FVR6-1", "A0A9J7FZH7-1", "A0A9J7FZW1-1", "A0A9J7G1H0-1", "A0A9J7G5F3-1", "A0A9J7G5N9-1", "A0A8C2LFT9-1", "A0A9J7G9D1-1", "A0A8C2MB66-1", "A0A9J7GD76-1", "A0A8C2LQS5-1", "A0A9J7GF22-1", "A0A9J7GF59-1", "A0A9J7GG74-1", "A0A9J7GGP1-1", "A0A9J7GHB3-1", "A0A9J7GI33-1", "A0A9J7GIC4-1", "A0A9J7GIN7-1", "A0A9J7GIR8-1", "A0A9J7GMF3-1", "A0A9J7GPQ3-1", "A0A9J7JPI2-1", "A0A9J7H5D8-1", "A0A9J7JZS0-1", "A0A9J7H4T9-1", "A0A9J7K4N6-1", "A0A9J7K8Y1-1", "A0A8C2M187-1", "A0A9J7KC95-1", "A0A9J7GR29-1", "A0A9J7GT89-1", "A0A9J7GX76-1", "A0A9J7GZH5-1", "A0A9J7H0E7-1", "A0A9J7H3L8-1", "A0A9J7H7J5-1", "A0A9J7H8W9-1", "A0A8C2LRT3-1", "A0A9J7JDU1-1", "A0A9J7JGG9-1", "A0A9J7JGQ1-1", "A0A9J7JIF8-1", "A0A9J7JPD7-1", "A0A9J7JPY1-1", "A0A9J7F9C4-1", "A0A9J7FC43-1", "A0A9J7JXX3-1", "A0A9J7EUQ5-1", "A0A9J7EXX8-1", "A0A8C2MSQ2-1", "A0A9J7F1D2-1", "A0A9J7F2F1-1", "A0A9J7F383-1", "A0A8C2LPE9-1", "A0A9J7FC95-1", "A0A8C2M1F6-1", "A0A9J7FF13-1", "A0A9J7FGF7-1", "A0A9J7FKM9-1", "A0A8C2LVR4-1", "A0A3L7GMP6-1", "A0A8C2M7I3-1", "A0A8C2MBI9-1", "A0A9J7JQZ1-1", "A0A8C2N3I1-1", "A0A3L7HK04-1", "A0A3L7I4E3-1", "A0A9J7FN24-1", "A0A9J7FYJ6-1", "A0A9J7G4B8-1", "A0A9J7G8N0-1", "A0A9J7G8N4-1", "A0A9J7GBL6-1", "A0A9J7H8W5-1", "A0A9J7H3S8-1", "A0A9J7H401-1", "A0A9J7H503-1", "A0A9J7H540-1", "A0A9J7KCN2-1", "A0A9J7H7W6-1", "A0A9J7H8E3-1", "A0A9J7H949-1", "A0A9J7GQY0-1", "A0A9J7GF26-1", "A0A9J7GHK2-1", "A0A9J7GHV2-1", "A0A9J7GK55-1", "A0A9J7GLT3-1", "A0A9J7GMK5-1", "A0A9J7GP29-1", "A0A9J7GR05-1", "A0A9J7GRB5-1", "A0A9J7GRC1-1", "A0A8C2M6X8-1", "A0A9J7GTU0-1", "A0A9J7GVC9-1", "A0A9J7H0W8-1", "A0A9J7H1I4-1", "A0A9J7H241-1", "A0A3L7I5Y4-1", "A0A9J7K3L1-1", "A0A9J7JU24-1", "A0A9J7JNT2-1", "A0A9J7JPF2-1", "A0A9J7JSB5-1", "A0A9J7JTJ0-1", "A0A9J7K6R5-1", "A0A9J7K851-1", "A0A9J7KB54-1", "A0A9J7KCM5-1", "A0A9J7JA07-1", "A0A9J7HEQ9-1", "A0A9J7J6E9-1", "A0A9J7J728-1", "A0A9J7K7C7-1", "A0A061IJA8-1", "A0A3L7HMX8-1", "A0A8C2LA64-1", "A0A8C2LE67-1", "A0A8C2LII0-1", "A0A8C2LTD1-1", "A0A8C2LTT6-1", "A0A8C2M4R2-1", "A0A8C2MC09-1", "A0A8C2MCI5-1", "A0A8C2N3U2-1", "A0A8C2M4P9-1", "A0A8C2QHS8-1", "A0A8C2QIA1-1", "A0A8C2QMB3-1", "A0A9J7F8T9-1", "A0A9J7FN52-1", "O55076-1", "P68180-1", "A0A061IJW6-1", "A0A3L7HQF4-1", "A0A3L7HRZ8-1", "A0A8C2LI15-1", "A0A8C2M497-1", "A0A8C2MAD7-1", "G3HBD4-1", "P25321-1", "A0A8C2MBP2-1", "A0A9J7JGR2-1", "A0A8C2QLT0-1", "G3HDE8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HUS7", "gene_name": "Srpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] } ] }, { "uniprot_ac": "A0A061HVM6", "gene_name": "Hipk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] } ] }, { "uniprot_ac": "A0A061HZ27", "gene_name": "Pik3cg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] } ] }, { "uniprot_ac": "A0A061I033", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] } ] }, { "uniprot_ac": "A0A061I8L6", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] } ] }, { "uniprot_ac": "A0A061I9F9", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] } ] }, { "uniprot_ac": "A0A061IJA8", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] } ] }, { "uniprot_ac": "A0A061IJW6", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] } ] }, { "uniprot_ac": "A0A061ILI7", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] } ] }, { "uniprot_ac": "A0A3L7GMP6", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] } ] }, { "uniprot_ac": "A0A3L7GPC7", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] } ] }, { "uniprot_ac": "A0A3L7HK04", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] } ] }, { "uniprot_ac": "A0A3L7HKC4", "gene_name": "Cdkl4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] } ] }, { "uniprot_ac": "A0A3L7HMX8", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] } ] }, { "uniprot_ac": "A0A3L7HQF4", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] } ] }, { "uniprot_ac": "A0A3L7HRZ8", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] } ] }, { "uniprot_ac": "A0A3L7HV37", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] } ] }, { "uniprot_ac": "A0A3L7I1E7", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0A3L7I1E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1E7" } ] } ] }, { "uniprot_ac": "A0A3L7I1R2", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] } ] }, { "uniprot_ac": "A0A3L7I4E3", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] } ] }, { "uniprot_ac": "A0A3L7I5Y4", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] } ] }, { "uniprot_ac": "A0A3L7I870", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] } ] }, { "uniprot_ac": "A0A3L7IB60", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] } ] }, { "uniprot_ac": "A0A3L7IBX6", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] } ] }, { "uniprot_ac": "A0A3L7ID00", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] } ] }, { "uniprot_ac": "A0A3L7IEL5", "gene_name": "LOC113833388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] } ] }, { "uniprot_ac": "A0A3L7IER1", "gene_name": "Stk38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] } ] }, { "uniprot_ac": "A0A8C2L7R1", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] } ] }, { "uniprot_ac": "A0A8C2LA64", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] } ] }, { "uniprot_ac": "A0A8C2LC89", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] } ] }, { "uniprot_ac": "A0A8C2LCN7", "gene_name": "Csnk2a2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] } ] }, { "uniprot_ac": "A0A8C2LDE5", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] } ] }, { "uniprot_ac": "A0A8C2LDQ8", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] } ] }, { "uniprot_ac": "A0A8C2LDU9", "gene_name": "Ern1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] } ] }, { "uniprot_ac": "A0A8C2LE67", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] } ] }, { "uniprot_ac": "A0A8C2LEI8", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] } ] }, { "uniprot_ac": "A0A8C2LFT9", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] } ] }, { "uniprot_ac": "A0A8C2LH99", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] } ] }, { "uniprot_ac": "A0A8C2LHE9", "gene_name": "Camk1d", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] } ] }, { "uniprot_ac": "A0A8C2LI14", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] } ] }, { "uniprot_ac": "A0A8C2LI15", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] } ] }, { "uniprot_ac": "A0A8C2LII0", "gene_name": "Cdk6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] } ] }, { "uniprot_ac": "A0A8C2LK72", "gene_name": "Rps6ka4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] } ] }, { "uniprot_ac": "A0A8C2LMC9", "gene_name": "Mknk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] } ] }, { "uniprot_ac": "A0A8C2LMJ0", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] } ] }, { "uniprot_ac": "A0A8C2LPE9", "gene_name": "Mast3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] } ] }, { "uniprot_ac": "A0A8C2LPR4", "gene_name": "Mapkapk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] } ] }, { "uniprot_ac": "A0A8C2LQB2", "gene_name": "Pak5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] } ] }, { "uniprot_ac": "A0A8C2LQS5", "gene_name": "Rps6kb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] } ] }, { "uniprot_ac": "A0A8C2LRT3", "gene_name": "Map3k5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] } ] }, { "uniprot_ac": "A0A8C2LTD1", "gene_name": "Prkcb", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] } ] }, { "uniprot_ac": "A0A8C2LTT6", "gene_name": "Prkd2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] } ] }, { "uniprot_ac": "A0A8C2LTW4", "gene_name": "Dclk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] } ] }, { "uniprot_ac": "A0A8C2LTZ7", "gene_name": "Tssk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] } ] }, { "uniprot_ac": "A0A8C2LVR4", "gene_name": "LOC100775051", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] } ] }, { "uniprot_ac": "A0A8C2LVV5", "gene_name": "Camk1g", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] } ] }, { "uniprot_ac": "A0A8C2LY02", "gene_name": "Mapk11", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] } ] }, { "uniprot_ac": "A0A8C2LY52", "gene_name": "Dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] } ] }, { "uniprot_ac": "A0A8C2LZT2", "gene_name": "Uhmk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] } ] }, { "uniprot_ac": "A0A8C2M0A2", "gene_name": "Mapk4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] } ] }, { "uniprot_ac": "A0A8C2M165", "gene_name": "Cdk4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] } ] }, { "uniprot_ac": "A0A8C2M187", "gene_name": "Map2k2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] } ] }, { "uniprot_ac": "A0A8C2M1F6", "gene_name": "Cdk19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] } ] }, { "uniprot_ac": "A0A8C2M3Y9", "gene_name": "Aurka", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] } ] }, { "uniprot_ac": "A0A8C2M497", "gene_name": "Prkch", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] } ] }, { "uniprot_ac": "A0A8C2M4P9", "gene_name": "Tesk1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] } ] }, { "uniprot_ac": "A0A8C2M4R2", "gene_name": "Map3k20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] } ] }, { "uniprot_ac": "A0A8C2M5A7", "gene_name": "Clk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] } ] }, { "uniprot_ac": "A0A8C2M5G2", "gene_name": "Map3k9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] } ] }, { "uniprot_ac": "A0A8C2M6A3", "gene_name": "Pnck", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] } ] }, { "uniprot_ac": "A0A8C2M6E6", "gene_name": "Mapk8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] } ] }, { "uniprot_ac": "A0A8C2M6X8", "gene_name": "Prkcq", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] } ] }, { "uniprot_ac": "A0A8C2M7I3", "gene_name": "Camkk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] } ] }, { "uniprot_ac": "A0A8C2M9B6", "gene_name": "Mapkapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] } ] }, { "uniprot_ac": "A0A8C2MAD7", "gene_name": "Pim1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] } ] }, { "uniprot_ac": "A0A8C2MB66", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] } ] }, { "uniprot_ac": "A0A8C2MBI9", "gene_name": "Tnk1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] } ] }, { "uniprot_ac": "A0A8C2MBP2", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] } ] }, { "uniprot_ac": "A0A8C2MBW2", "gene_name": "Tp53rk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] } ] }, { "uniprot_ac": "A0A8C2MC09", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] } ] }, { "uniprot_ac": "A0A8C2MCI5", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] } ] }, { "uniprot_ac": "A0A8C2MCX3", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] } ] }, { "uniprot_ac": "A0A8C2MEU5", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] } ] }, { "uniprot_ac": "A0A8C2MFN1", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] } ] }, { "uniprot_ac": "A0A8C2MH43", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] } ] }, { "uniprot_ac": "A0A8C2MJ02", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] } ] }, { "uniprot_ac": "A0A8C2ML15", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] } ] }, { "uniprot_ac": "A0A8C2MMI4", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] } ] }, { "uniprot_ac": "A0A8C2MMQ4", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] } ] }, { "uniprot_ac": "A0A8C2MMZ5", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] } ] }, { "uniprot_ac": "A0A8C2MP62", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] } ] }, { "uniprot_ac": "A0A8C2MQ42", "gene_name": "Cdkl5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] } ] }, { "uniprot_ac": "A0A8C2MQ73", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] } ] }, { "uniprot_ac": "A0A8C2MQL9", "gene_name": "LOC100766643", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] } ] }, { "uniprot_ac": "A0A8C2MQM0", "gene_name": "Camkk2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2MQM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQM0" } ] } ] }, { "uniprot_ac": "A0A8C2MQS3", "gene_name": "Taok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MQS3", "database": "UniProtKB", "url": 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} ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N3U2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N3U2" } ] } ] }, { "uniprot_ac": "A0A8C2N457", "gene_name": "Rps6ka1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N457" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2N457", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N457" } ] } ] }, { "uniprot_ac": "A0A8C2N4W2", "gene_name": "Map3k2", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2N4W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N4W2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] } ] }, { "uniprot_ac": "A0A9J7EZ49", "gene_name": "Prkg2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] } ] }, { "uniprot_ac": "A0A9J7EZ53", "gene_name": "Map4k4", "activity": [ { "ec_number": "2.7.11.1", "activity": 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"evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] } ] }, { "uniprot_ac": "A0A9J7F3R3", "gene_name": "Braf", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] } ] }, { "uniprot_ac": "A0A9J7F4P4", "gene_name": "Tnni3k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] } ] }, { "uniprot_ac": "A0A9J7F5B0", "gene_name": "Plk4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] } ] }, { "uniprot_ac": "A0A9J7F773", "gene_name": "Pklr", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] } ] }, { "uniprot_ac": 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ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] } ] }, { "uniprot_ac": "A0A9J7F8V5", "gene_name": "Nek3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] } ] }, { "uniprot_ac": "A0A9J7F927", "gene_name": "Map3k12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] } ] }, { "uniprot_ac": "A0A9J7F985", "gene_name": "LOC118237656", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] } ] }, { "uniprot_ac": "A0A9J7F9C4", "gene_name": "Nek5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] } ] }, { "uniprot_ac": "A0A9J7FBT0", "gene_name": "Speg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] } ] }, { "uniprot_ac": "A0A9J7FC43", "gene_name": "Cdk15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] } ] }, { "uniprot_ac": "A0A9J7FC95", "gene_name": "Lrrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] } ] }, { "uniprot_ac": "A0A9J7FCC7", "gene_name": "Csnk1g3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] } ] }, { "uniprot_ac": "A0A9J7FD79", "gene_name": "Map3k4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] } ] }, { "uniprot_ac": "A0A9J7FDV1", "gene_name": "Cdk7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] } ] }, { "uniprot_ac": "A0A9J7FEY2", "gene_name": "Csnk1a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] } ] }, { "uniprot_ac": "A0A9J7FF13", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] } ] }, { "uniprot_ac": "A0A9J7FF35", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] } ] }, { "uniprot_ac": "A0A9J7FFS7", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] } ] }, { "uniprot_ac": "A0A9J7FGD3", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] } ] }, { "uniprot_ac": "A0A9J7FGF7", "gene_name": "LOC100751450", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] } ] }, { "uniprot_ac": "A0A9J7FI14", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FKM1", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] } ] }, { "uniprot_ac": "A0A9J7FKM9", "gene_name": "LOC113834545", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] } ] }, { "uniprot_ac": "A0A9J7FLY5", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] } ] }, { "uniprot_ac": "A0A9J7FN24", "gene_name": "Alpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] } ] }, { "uniprot_ac": "A0A9J7FN52", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] } ] }, { "uniprot_ac": "A0A9J7FN68", "gene_name": "Mast1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] } ] }, { "uniprot_ac": "A0A9J7FNF0", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] } ] }, { "uniprot_ac": "A0A9J7FS53", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] } ] }, { "uniprot_ac": "A0A9J7FUL0", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] } ] }, { "uniprot_ac": "A0A9J7FVR6", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] } ] }, { "uniprot_ac": "A0A9J7FYJ6", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FYY3", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] } ] }, { "uniprot_ac": "A0A9J7FZ18", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] } ] }, { "uniprot_ac": "A0A9J7FZA7", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"https://www.uniprot.org/uniprotkb/A0A9J7FZW1" } ] } ] }, { "uniprot_ac": "A0A9J7FZY8", "gene_name": "Pik3cb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZY8", "database": "UniProtKB", "url": 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G368" } ] } ] }, { "uniprot_ac": "A0A9J7G3C1", "gene_name": "Dapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G3C1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3C1" } ] } ] }, { "uniprot_ac": "A0A9J7G4B8", "gene_name": "Cdk18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7G4B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G4B8" } ] } ] }, { "uniprot_ac": "A0A9J7G5F3", "gene_name": "Plk5", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5F3" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7G5F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5F3" } ] } ] }, { "uniprot_ac": "A0A9J7G5N9", "gene_name": "Stk35", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] } ] }, { "uniprot_ac": "A0A9J7G6S5", "gene_name": "Trpm7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] } ] }, { "uniprot_ac": "A0A9J7G8N0", "gene_name": "LOC100770044", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N0", "database": 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"ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GAB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAB0" } ] } ] }, { "uniprot_ac": "A0A9J7GAF4", "gene_name": "Stk10", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GAF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAF4" } ] } ] }, { "uniprot_ac": "A0A9J7GBF4", "gene_name": "Csnk1d", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GBF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"uniprot_ac": "A0A9J7GF22", "gene_name": "Aatk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF22" } ] } ] }, { "uniprot_ac": "A0A9J7GF26", "gene_name": "LOC100752478", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF26" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF26" } ] } ] }, { "uniprot_ac": "A0A9J7GF59", "gene_name": "LOC103160391", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] } ] }, { "uniprot_ac": "A0A9J7GFS3", "gene_name": "Aak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] } ] }, { "uniprot_ac": "A0A9J7GG74", "gene_name": "Cdkl3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] } ] }, { "uniprot_ac": "A0A9J7GGP1", "gene_name": "Map4k1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] } ] }, { "uniprot_ac": "A0A9J7GHB3", "gene_name": "Map2k4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] } ] }, { "uniprot_ac": "A0A9J7GHK2", "gene_name": "LOC100753695", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] } ] }, { "uniprot_ac": "A0A9J7GHV2", "gene_name": "LOC100773845", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] } ] }, { "uniprot_ac": "A0A9J7GI33", "gene_name": "Map3k10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] } ] }, { "uniprot_ac": "A0A9J7GIC4", "gene_name": "Stk26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] } ] }, { "uniprot_ac": "A0A9J7GIM1", "gene_name": "Cdk16", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIM1" } ] } ] }, { "uniprot_ac": "A0A9J7GIN7", "gene_name": "Eif2ak3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] } ] }, { "uniprot_ac": "A0A9J7GIR8", "gene_name": "Prkcg", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] } ] }, { "uniprot_ac": "A0A9J7GJE4", "gene_name": "Stk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJE4" } ] } ] }, { "uniprot_ac": "A0A9J7GK55", "gene_name": "Aurkc", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GK55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GK55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK55" } ] } ] }, { "uniprot_ac": "A0A9J7GLT3", "gene_name": "LOC113838166", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLT3" } ] } ] }, { "uniprot_ac": "A0A9J7GMF3", "gene_name": "LOC103158537", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMF3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMF3" } ] } ] }, { "uniprot_ac": "A0A9J7GMK5", "gene_name": "Sbk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMK5" } ] } ] }, { "uniprot_ac": "A0A9J7GP29", "gene_name": "Stk32a", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] } ] }, { "uniprot_ac": "A0A9J7GPQ3", "gene_name": "Pim2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GPQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPQ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GPQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPQ3" } ] } ] }, { "uniprot_ac": "A0A9J7GQ42", "gene_name": "Map3k1", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ42" } ] } ] }, { "uniprot_ac": "A0A9J7GQY0", "gene_name": "Wnk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQY0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQY0" } ] } ] }, { "uniprot_ac": "A0A9J7GR05", "gene_name": "Alpk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR05" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR05" } ] } ] }, { "uniprot_ac": "A0A9J7GR29", "gene_name": "Ern2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GR29", "database": 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H2E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2E9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H2E9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2E9" } ] } ] }, { "uniprot_ac": "A0A9J7H2P9", "gene_name": "LOC113839030", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H2P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2P9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H2P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2P9" } ] } ] }, { "uniprot_ac": "A0A9J7H2T6", "gene_name": "Ttn", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H2T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2T6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H2T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2T6" } ] } ] }, { "uniprot_ac": "A0A9J7H3E2", "gene_name": "LOC113836728", "activity": [ { "ec_number": "2.7.2.3", "activity": "(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP.", "evidence": [ { "id": "A0A9J7H3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3E2" } ] }, { "ec_number": "2.7.2.3", "activity": "", "evidence": [ { "id": "A0A9J7H3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3E2" } ] } ] }, { "uniprot_ac": "A0A9J7H3L8", "gene_name": "Csnk2a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3L8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H3L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3L8" } ] } ] }, { "uniprot_ac": "A0A9J7H3M5", "gene_name": "Myo3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3M5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H3M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3M5" } ] } ] }, { "uniprot_ac": "A0A9J7H3N1", "gene_name": "Obscn", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3N1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H3N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3N1" } ] } ] }, { "uniprot_ac": "A0A9J7H3S8", "gene_name": "Wnk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H3S8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3S8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H3S8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H3S8" } ] } ] }, { "uniprot_ac": "A0A9J7H401", "gene_name": "Akt2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H401", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H401" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H401", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H401" } ] } ] }, { "uniprot_ac": "A0A9J7H4N5", "gene_name": "LOC113837096", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H4N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4N5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H4N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4N5" } ] } ] }, { "uniprot_ac": "A0A9J7H4T9", "gene_name": "Ciita", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H4T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H4T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4T9" } ] } ] }, { "uniprot_ac": "A0A9J7H503", "gene_name": "LOC100752185", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H503", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H503" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H503", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H503" } ] } ] }, { "uniprot_ac": "A0A9J7H540", "gene_name": "LOC113837157", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H540", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H540" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H540", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H540" } ] } ] }, { "uniprot_ac": "A0A9J7H5D8", "gene_name": "Nek8", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H5D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5D8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H5D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5D8" } ] } ] }, { "uniprot_ac": "A0A9J7H6V8", "gene_name": "Sbk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H6V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6V8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H6V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6V8" } ] } ] }, { "uniprot_ac": "A0A9J7H7J5", "gene_name": "Prkacb", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H7J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7J5" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A9J7H7J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7J5" } ] } ] }, { "uniprot_ac": "A0A9J7H7W6", "gene_name": "LOC113837158", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H7W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7W6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H7W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7W6" } ] } ] }, { "uniprot_ac": "A0A9J7H8E3", "gene_name": "Map3k15", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H8E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8E3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7H8E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8E3" } ] } ] }, { "uniprot_ac": "A0A9J7H8L4", "gene_name": "Irak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H8L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8L4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H8L4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8L4" } ] } ] }, { "uniprot_ac": "A0A9J7H8U3", "gene_name": "Wnk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H8U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H8U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8U3" } ] } ] }, { "uniprot_ac": "A0A9J7H8W5", "gene_name": "Nrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7H8W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8W5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7H8W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8W5" } ] } ] }, { "uniprot_ac": "A0A9J7H8W9", "gene_name": "LOC100767231", "activity": [ { "ec_number": "2.7.11.1", "activity": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7HEQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEQ9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7HEQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HEQ9" } ] } ] }, { "uniprot_ac": "A0A9J7J1N3", "gene_name": "Limk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7J1N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J1N3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7J1N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J1N3" } ] } ] }, { "uniprot_ac": "A0A9J7J5Z8", "gene_name": "Camk2g", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { 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"https://www.uniprot.org/uniprotkb/A0A9J7JBH0" } ] } ] }, { "uniprot_ac": "A0A9J7JDU1", "gene_name": "Cdc42bpg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JDU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JDU1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JDU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JDU1" } ] } ] }, { "uniprot_ac": "A0A9J7JGG9", "gene_name": "Riok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JGG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGG9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JGG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGG9" } ] } ] }, { "uniprot_ac": "A0A9J7JGQ1", "gene_name": "Trpm6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGQ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JGQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGQ1" } ] } ] }, { "uniprot_ac": "A0A9J7JGR2", "gene_name": "Rock1", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JGR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGR2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A9J7JGR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JGR2" } ] } ] }, { "uniprot_ac": "A0A9J7JHJ2", "gene_name": "Mast2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] } ] }, { "uniprot_ac": "A0A9J7JIF8", "gene_name": "Prkd1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] } ] }, { "uniprot_ac": "A0A9J7JIW6", "gene_name": "Pkn1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIW6" } ] } ] }, { "uniprot_ac": "A0A9J7JJV6", "gene_name": "Mark1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JJV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJV6" } ] } ] }, { "uniprot_ac": "A0A9J7JKJ1", "gene_name": "Sik2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JKJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JKJ1" } ] } ] }, { "uniprot_ac": "A0A9J7JLH7", "gene_name": "Mark2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7JLH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JLH7" } ] } ] }, { "uniprot_ac": "A0A9J7JNT2", "gene_name": "LOC113835854", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNT2" } ] } ] }, { "uniprot_ac": "A0A9J7JNU2", "gene_name": "Tnk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JNU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNU2" } ] } ] }, { "uniprot_ac": "A0A9J7JPD7", "gene_name": "Lmtk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] } ] }, { "uniprot_ac": "A0A9J7JPE2", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] } ] }, { "uniprot_ac": "A0A9J7JPF2", "gene_name": "LOC100765388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] } ] }, { "uniprot_ac": "A0A9J7JPI2", "gene_name": "Ksr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] } ] }, { "uniprot_ac": "A0A9J7JPY1", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPY1" } ] } ] }, { "uniprot_ac": "A0A9J7JQD1", "gene_name": "Ulk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JQD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQD1" } ] } ] }, { "uniprot_ac": "A0A9J7JQV6", "gene_name": "Pkm", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7JQV6", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] } ] }, { "uniprot_ac": "A0A9J7JRJ8", "gene_name": "Mark3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] } ] }, { "uniprot_ac": "A0A9J7JSB5", "gene_name": "LOC113836186", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] } ] }, { "uniprot_ac": "A0A9J7JTJ0", "gene_name": "LOC113838440", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] } ] }, { "uniprot_ac": "A0A9J7JTL3", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] } ] }, { "uniprot_ac": "A0A9J7JU24", "gene_name": "Camk2a", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] } ] }, { "uniprot_ac": "A0A9J7JXM2", "gene_name": "Dcaf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] } ] }, { "uniprot_ac": "A0A9J7JXX3", "gene_name": "Map3k3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] } ] }, { "uniprot_ac": "A0A9J7JYC5", "gene_name": "Nme7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] } ] }, { "uniprot_ac": "A0A9J7JYU7", "gene_name": "Mink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] } ] }, { "uniprot_ac": "A0A9J7JZS0", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] } ] }, { "uniprot_ac": "A0A9J7K1H4", "gene_name": "LOC113837295", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] } ] }, { "uniprot_ac": "A0A9J7K2Q7", "gene_name": "LOC100773089", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] } ] }, { "uniprot_ac": "A0A9J7K2S5", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] } ] }, { "uniprot_ac": "A0A9J7K3L1", "gene_name": "LOC100755238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] } ] }, { "uniprot_ac": "A0A9J7K3S4", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] } ] }, { "uniprot_ac": "A0A9J7K4N6", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] } ] }, { "uniprot_ac": "A0A9J7K6R5", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] } ] }, { "uniprot_ac": "A0A9J7K7C7", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] } ] }, { "uniprot_ac": "A0A9J7K7D8", "gene_name": "LOC100757073", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] } ] }, { "uniprot_ac": "A0A9J7K851", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] } ] }, { "uniprot_ac": "A0A9J7K8Y1", "gene_name": "Lmtk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] } ] }, { "uniprot_ac": "A0A9J7K953", "gene_name": "Cdkl1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] } ] }, { "uniprot_ac": "A0A9J7KB54", "gene_name": "LOC118237737", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] } ] }, { "uniprot_ac": "A0A9J7KC95", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] } ] }, { "uniprot_ac": "A0A9J7KCM5", "gene_name": "LOC113837018", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] } ] }, { "uniprot_ac": "A0A9J7KCN2", "gene_name": "LOC107977720", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] } ] }, { "uniprot_ac": "A0A9J7KDV7", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] } ] }, { "uniprot_ac": "A0A9J7KE81", "gene_name": "Nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] } ] }, { "uniprot_ac": "A0A9J7KFV8", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] } ] }, { "uniprot_ac": "G3GRI0", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] } ] }, { "uniprot_ac": "G3GRR1", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] } ] }, { "uniprot_ac": "G3GUA6", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] } ] }, { "uniprot_ac": "G3GVI7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] } ] }, { "uniprot_ac": "G3GWJ3", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] } ] }, { "uniprot_ac": "G3GWN1", "gene_name": "LOC100755333", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] } ] }, { "uniprot_ac": "G3GX92", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] } ] }, { "uniprot_ac": "G3GY19", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] } ] }, { "uniprot_ac": "G3GYQ3", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] } ] }, { "uniprot_ac": "G3H3C3", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] } ] }, { "uniprot_ac": "G3H3S6", "gene_name": "Lats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] } ] }, { "uniprot_ac": "G3H5L5", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] } ] }, { "uniprot_ac": "G3H8I4", "gene_name": "Lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] } ] }, { "uniprot_ac": "G3HAZ9", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] } ] }, { "uniprot_ac": "G3HBD4", "gene_name": "LOC100765914", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] } ] }, { "uniprot_ac": "G3HBI7", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] } ] }, { "uniprot_ac": "G3HCC1", "gene_name": "Chek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] } ] }, { "uniprot_ac": "G3HDE8", "gene_name": "Pck2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] } ] }, { "uniprot_ac": "G3HEH4", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] } ] }, { "uniprot_ac": "G3HER3", "gene_name": "Tssk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] } ] }, { "uniprot_ac": "G3HLS6", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] } ] }, { "uniprot_ac": "G3HMY1", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] } ] }, { "uniprot_ac": "G3HT38", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] } ] }, { "uniprot_ac": "G3HTW4", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] } ] }, { "uniprot_ac": "G3HV08", "gene_name": "Cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] } ] }, { "uniprot_ac": "G3HVB0", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] } ] }, { "uniprot_ac": "G3HVN3", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] } ] }, { "uniprot_ac": "G3HX91", "gene_name": "Prkd3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] } ] }, { "uniprot_ac": "G3HXQ8", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] } ] }, { "uniprot_ac": "G3HY42", "gene_name": "Akt3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] } ] }, { "uniprot_ac": "G3HZ18", "gene_name": "LOC100756665", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] } ] }, { "uniprot_ac": "G3HZH7", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] } ] }, { "uniprot_ac": "G3HZU1", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] } ] }, { "uniprot_ac": "G3I0W5", "gene_name": "Stk38l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] } ] }, { "uniprot_ac": "G3I3E2", "gene_name": "Pdik1l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] } ] }, { "uniprot_ac": "G3I3Z8", "gene_name": "Rps6kb2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] } ] }, { "uniprot_ac": "G3I472", "gene_name": "LOC100760228", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] } ] }, { "uniprot_ac": "G3I5H0", "gene_name": "Cilk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] } ] }, { "uniprot_ac": "G3I724", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3I724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I724" } ] } ] }, { "uniprot_ac": "G3I7I8", "gene_name": "Chek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I7I8" } ] } ] }, { "uniprot_ac": "G3I8T5", "gene_name": "Map3k6", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = 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This record is derived from a genomic sequence (NW_003615260.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027239961", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027239961" } ] }, { "annotation": "Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCM7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM7#function" }, { "database": "UniProtKB", "id": "ARBA00002860", "url": "https://www.uniprot.org/uniprotkb/ARBA00002860#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCM7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Sgcb", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM7", "locus": {} } ], "crossref": [ { "id": "A0A9J7KCM7", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7KCM7", "database": "AlphaFoldDB", "categories": [] }, { "id": "100756579", "url": "https://www.ncbi.nlm.nih.gov/gene/100756579", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027659", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027659", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756579", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756579", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KCM7", "url": "https://www.orthodb.org/?gene=A0A9J7KCM7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21142", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21142", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21142:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21142:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04790", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04790", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027239961", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027239961", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KCM7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KCM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MREKAVERRNVNKEHNSNFKAGYIPIDEDRLHKTGLRGRKGNLAICVIVLLFILAVINLLITLVIWAVIRIGPNGCDSMEFHESGLLRFKQVSDMGVIHPLYKSTVGGRRNENLVITGNNQPIVFQQGTTKLSVEKNKTSITSDIGMQFFDPRTQNILFSTDYETHEFHLPSGVKSLNVQKASTERITSNATSDLNIKVDGRAIVRGNEGVFIMGKTIEFHMGGNVELKAENSIILNGTVMVSPTRLPSSSSGDQSGSGDWVRYKLCMCADGTLFKVQVTGHNMGCQVSDNPCGNTH", "length": 297, "header": "tr|A0A9J7KCM7-1|A0A9J7KCM7_CRIGR Isoform 1 of Beta-sarcoglycan OS=Cricetulus griseus OX=10029 GN=Sgcb PE=3 SV=1 CANONICAL=A0A9J7KCM7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KCM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM7/entry#A0A9J7KCM7-1", "sequence": { "sequence": "MREKAVERRNVNKEHNSNFKAGYIPIDEDRLHKTGLRGRKGNLAICVIVLLFILAVINLLITLVIWAVIRIGPNGCDSMEFHESGLLRFKQVSDMGVIHPLYKSTVGGRRNENLVITGNNQPIVFQQGTTKLSVEKNKTSITSDIGMQFFDPRTQNILFSTDYETHEFHLPSGVKSLNVQKASTERITSNATSDLNIKVDGRAIVRGNEGVFIMGKTIEFHMGGNVELKAENSIILNGTVMVSPTRLPSSSSGDQSGSGDWVRYKLCMCADGTLFKVQVTGHNMGCQVSDNPCGNTH", "length": 297, "header": "tr|A0A9J7KCM7-1|A0A9J7KCM7_CRIGR Isoform 1 of Beta-sarcoglycan OS=Cricetulus griseus OX=10029 GN=Sgcb PE=3 SV=1 CANONICAL=A0A9J7KCM7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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"database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00093", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00093", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00754", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00754", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08742", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08742", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304955", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304955", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KCM9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KCM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLPALLFGMLWALTHGRWCEQTETIHIEEEITPRQEDLVPCTSLYHYIRLGWRLDLPWRGHVGLTRPPALGLCAIYKPPETRPATGNRTVRACCPGWGGPHCTDALAEASPKGHCFVTWQCQPPAGPANSSAGSLEECCAQPSGHSWWDSSSQMCLSCSGQYHSSNASSEALLPLAGAVGQLWSQRQRLSATCSTWSGFHYQTFDGRHYHFLGQCTYLLAGAVDSTWAVHLRPRVHCPKPTHCSLVQVMMGPEEVLIQDGEVSVKGQPVPVGEPRLLHGMSLQWQGDWLVLFGGLGVVVRLDRSSSISISVDHEFWGRTQGLCGLYNGQPEDDFVEPEGGLAMLAATFGNSWRLPGYEPGCLDAVEVAKGCEGALQGTQTGLEAGKLQAQAQDMCHKLLEDPFWQCHAQVPLDEYHETCLFAYCVGTKAGPEGQQEAVCATFANYARACARKHIYVHWRKPGFCERLCPGGQLYSDCVSSCPPSCSAVAQGEEGSCGKECVSGCECPDSLFWDGSRCVPAAHCPCYHRRQRYAPGDIVNQLCNPCICQDGRWHCAQALCPAECAVGGDGHYLTFDGRSFSFRGNPGCHYSLVQDSVKGQLLIALEHGACDTGSCLHALSVFLGNTHIQLRYSGAVLVDGKDIDLPWIAEGFNVSHASSTFLLLRWPGAWVLWGVADSAAYITLDPHHAYQVQGLCGTFTWKQQDDFLTPAGDIETSVAAFAGKFKVSGDGRCPWMDNIPLSACSTYSQRLVFAEAACAILHGPTFQECHGLVDRESFRLRCLEAVCGCAPGRNCLCSVLSAYARRCAQEGVLLQWRNETLCPILCPGGQAYQECAPMCGHHCGEPEECKELGGCVAGCNCPPGLLWAPEGQCVSPSMCPCQLGGHHYTFGTTTTTKDCSHCVCQERGLWNCTSNHCPPQRALCPQEFIYAPGACLLTCDSLSANHSCLAGSTDGCVCPPGTVLLDKRCVSPELCPCRHNGQWYPPNATIQEDCNICVCQGQRWHCTGQRCSGWCQASGAPHYVTFDGLVLTFPGACEYLLVREASGRFSVSIQNLPCGASGLTCTKALAVRLDGTVVHMLRGQAVTVNGVSIKLPKVYTGPGLSLHHAGIFLLLTTRLGLTLLWDGGTRVLVRLSPHFHGRVVGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLNPLCPELGDLPHPCTVNTHRVNWAQARCGVILQPIFAPCHTEVPPQQHYEWCVYDACGCDTGGDCECLCSAIAAYADECARHRHHVRWRSQGLCPLQCEGGQVYEACGSTCPPTCHDHHPETRWQCQAISCVEGCFCPEGTLLHGGACVELPACPCEWDGSFFPPGTVLQKDCGNCTCQESRWHCGGDGVPCEEMKTGCAEGEALCRESGHCVPLEWLCDNQDDCGDGSDEEGCATSGCGEGQMSCQSGHCLPLALLCDGQDDCGDGTDEKGCPCPHGSLACADGRCLPPALLCNGHPDCLDAADEESCLGQLSCTSGEISCEDGTCIRARQLCDGVWDCPEGADEGPGHCPLPSLPTPPAGTWQSPSTSSLNTASSPMGSASPASPCGLFEFQCRSGECTPQGWRCDQEEDCPDASDELDCGGPCMLHQVPCAHSQHCLSPGQLCDGVPQCPDGSDEDPEACEGLSVPGGPNRTGVPCPEFSCPNGTCIDFLLVCDGNPDCELDNEAESSLEEQGCGAWSSWGPWEQCSQTCGPGVQGRSRHCSPSSLPVLKNCTGPQHQSQACFMEACPVDAEWSSWSPWSLCSEPCGGTMTRHRQCHPPQNGGQDCVLLPGSPRTTHQTNPCPQEGCPNATCFGELVFQPCAPCPLTCDDISDQTVCSPDRPCSSPGCWCPEGQVLGTDGRCLRPRQCPCLVNGTRYWPGQHIKVNCQLCLCQDGRPHRCRPNPECSVDCGWSSWSPWAECLGPCSSQSLQWSFRSPNNPRLSGRGRQCHGIHRKARRCQTEPCEGCEQWGLMHHVGERWRGGPCMVCECLHGGVTRCSLYCPLGSCPQGWVLVEGMGESCCHCALPGKNQTLAPRTTPAPASSPQIGAPLITYVLPPLGNACYSPLGLAQLPMWASSQHLEHPTWAAMGAPTTGPGPREDAYAEWHSQPLYLQMDLMQPRNLTGIMVQGVGSSAAYVASLSLQFSSDGLQWHDSVSSLPKSQPPPTLFPGSPSHMAPEVWTFNQMVQARYVRVWPHSGRHSDNIQHNIFLWVELLGLSPRTPACPENRHHCASGECVPKGGPCDGAVDCRDGSDDEACRPLRAGTTSRVHSTTRTPALSSTSTQPGTFPSQPREGVADMEHQQPKQEPSMPTAGAAGPIHASETPLPVSGKSMQMVTTISTFPPGAKSLNPGMAAVTALPPHSVTPVTPAGQSVTPWHFPPVWCSPGQLPCAVCTEAACDAGRKDCLGGSHEKHWATPGPFTIPTTALPELPASMTLCSPNQLSCGSGECLPREQRCDLQLNCQDGSDEDNCVDCVLAPWSVWSDCSHSCGLGLIFQRRELLRPPLPGGSCLLDQLRSQPCFMQACPVAGAWAEWGPWEPCSVSCGGGHQSRQRSCVDPPPKNGGAPCPGPSHERAPCSLQLCPGDTDCEPGLVHVNSELCQKGLVPPCPPSCLDPEANRSCNGQCMEGCRCPPGLFLQDSRCMPLSECPCLVGQDLRQPGLAFLLDNCSECMCEKGTLLCKSGGCSQSCGWSAWSPWTPCDHSCGSGVRARFRSPSNPPAAFGGTPCEGDRQELQACYTDCGAEIPGWTTWTPWSSCSQSCLVPEGDPGWRQRSRLCPSSRDTFCPGEATQEEPCSPPVCPVPSAWGLWASWSTCSASCNGGIQSRGRSCSSVAPGNPVCPGPHTQTRDCNMHPCTDQCPGNMVFRSAEQCHEEGGPCPQLCLAQDSGVECTGSCAPSCNCPPGLFLHNASCLPRSQCPCQLHGRLYAAGAVARLDCNNCTCVSGEMVCTAELCPVACGWSPWTPWSLCSQSCNVGIRRRFRAGTAPPAAFGGAECEGPNVDAEFCSLRPCQGPGAEWSSWSLCSVPCGGGYRNRTQGGGPHSPIEFSTCSLQPCAGPVPGVCPKGQQWLDCAQGPASCAHLSTHRETNQTCQPGCYCLSGMLLLNNVCVPAKDCPCTHRGRLHPPGSAVVHPCENCSCVSGLITNCSSWPCEEGQPAWSPWTPWSMCSASCSPAQRHRHRFCATPPRMEPFSQALLPTVAPTTHCPGSEAEEEPCLLPGCDQAGSWGPWGPWSGCSRSCGGGLRSRTRACDQPPPQGLGDFCEGPQAQGEACQSQPCPVTNCSTIEGAEYSHCGPPCPRSCDDLVHCVWHCQPGCYCPLGKVLSADGTICVQPSHCSCLDLLTGKRHHPGTQLTRPDGCNHCTCMEGRLHCTDLPCQVPGGWCPWSEWTACSQPCRGQTRTRSRACVCPAPQHGGAPCPEEAGETGMQHQREACPNPTACPVDGAWSPWGPWSSCDACLGQSLRSRVCSHPPTADGGRPCPGGHQQSRPCRDSSTLCTDCGGGQDLLPCGQPCPRSCQDLSLGSICLPGSEGCQSGCGCPPGQLSQDGLCVLPADCHCHFQPRAMGIPENQSRSAGSTLSSWESLEPGEVVTGPCDNCTCVAGILQCHEVPSCPGPGMWSSWGPWEKCSVSCGGGEQLRSRHCARPPCPGLARQSRACHIQVCRGCQVSQLYRACQPGEGCPFTCAHIAGQVACFSESCEEGCHCPEGTFQHRLACVQLFCTELWLTLSPRSQPSGSQSCVYQEMPPEAQVLPLFPQVSWELLHRLTALLLQELGVASTAPRTYPGLLEDEGQTLGPGDELAPGQMLQTVCGNCSCVHGKLSCSMEECSRVHGSFGPWSTWSPCSQPCGGLGTRTRTRQCVHPHPTLVPGGLSCHGPLQDLEYCFSPECPGAARSMVEPVTGLAGGWGPWSPWSPCSHSCTDPVHPTWRSRTRLCLGNCTVGDSLQERPCNLPSCTALDLCPGPGCGSRNCSWTSWAPWEPCSRSCGVGQQRRLRAYNPPGPGGHWCSDILTAYQERRFCNLRACPVPGGWSRWSPWSWCDRSCGGGRSLRSRSCSSPPPKNGGASCVGERHHVRSCNPMPCEEGCPAGMEIVSCANRCPHSCSDLQEGVMCQEDQACQLGCRCSQGFLEQDGGCVPVGHCECTDAQGRSWAPGSQHQNACNNCSCQAGQLSCSAQACPPPAYCAWSHWSAWSPCSHSCGPQGQQSRFRSSTSGSWALECQKEQSQSQFCPEAPCPPLCLHEDHPRALGDSWLQGECQQCSCTPEGVICRDTECAVPGGWTLWSSWSHCSVSCGGGSQVRTRSCMVLSPQHGSLPCQGPDTQTQPCGQQLCLQVLETCSWGAWGPCSHSCGTGLASRSGSCPCLLTEEDSMCNDTFSRLDTQACYLGPCQEDCIWSDWSSWTRCSCKVLVQQRYRHQGPAPGRAVGSAPCTRLDGHFRPCTIDNCSEDGCPPPFEFQACGSPCAGLCATHRSHQLCQDLPPCQPGCYCPKGLLEQAGGCILPEQCNCWHTSGEGTRVPLAPGDHLKLGCKECECRSGELQCSSQGCEGLLPLTEWSEWSPCGPCLPLSALAPASKTALEGHWPLNTSGLPQTSVTLLASEQYRHRLCLDPETGRPWTGDPALCTVPLSQQRLCPDPGVCNDTCQWGPWGPWSPCQVPCSGGFKLRWREARDSSGGECRGPWAQTESCNMGSCPGESCETRDTVFTLDCANQCPRSCADLWDGVQCLQGHCSPGCRCPPGQLVQDGHCVPISSCHCGLPSANGSWELAPTQVVQLDCHNCTCINGSLVCPYLQCPVVGPWSAWSQCSAACGGGTMVRHRSCEERPEGTPCQALDMLQWQECNLQACPECPPGQVLSTCATLCPSLCSHLQPGTICVREPCQLGCSCPGGQLLHNGTCLSPAACPCSQLSLPWGLTLPLEEQAQELPAGTVLTWNCTHCTCQGGAFICSSIDCQGCPPGEIWQHVAPGELGPCEKTCPEMNVTLSWSNCTKAQAPGCVCQPGHFRSQTGVCVPEDHCECWHHGRPHLPGSEWQEACDSCHCLHGKSICTRHCPSLTCAQGQVMMQEPGSCCPICQQDTLGMQEEEPASCQYLTELRNLTKGPCHLDQVEVSYCSGQCRSSTNVMTEEPYLQSQCDCCSYRLDPDSPVRILNLHCPDGHTEPVVLPVIHSCQCSVCQGGDFSKH", "length": 5185, "header": "tr|A0A9J7KCM9-1|A0A9J7KCM9_CRIGR Isoform 1 of SCO-spondin OS=Cricetulus griseus OX=10029 GN=Sspop PE=3 SV=1 CANONICAL=A0A9J7KCM9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KCM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM9/entry#A0A9J7KCM9-1", "sequence": { "sequence": "MLLPALLFGMLWALTHGRWCEQTETIHIEEEITPRQEDLVPCTSLYHYIRLGWRLDLPWRGHVGLTRPPALGLCAIYKPPETRPATGNRTVRACCPGWGGPHCTDALAEASPKGHCFVTWQCQPPAGPANSSAGSLEECCAQPSGHSWWDSSSQMCLSCSGQYHSSNASSEALLPLAGAVGQLWSQRQRLSATCSTWSGFHYQTFDGRHYHFLGQCTYLLAGAVDSTWAVHLRPRVHCPKPTHCSLVQVMMGPEEVLIQDGEVSVKGQPVPVGEPRLLHGMSLQWQGDWLVLFGGLGVVVRLDRSSSISISVDHEFWGRTQGLCGLYNGQPEDDFVEPEGGLAMLAATFGNSWRLPGYEPGCLDAVEVAKGCEGALQGTQTGLEAGKLQAQAQDMCHKLLEDPFWQCHAQVPLDEYHETCLFAYCVGTKAGPEGQQEAVCATFANYARACARKHIYVHWRKPGFCERLCPGGQLYSDCVSSCPPSCSAVAQGEEGSCGKECVSGCECPDSLFWDGSRCVPAAHCPCYHRRQRYAPGDIVNQLCNPCICQDGRWHCAQALCPAECAVGGDGHYLTFDGRSFSFRGNPGCHYSLVQDSVKGQLLIALEHGACDTGSCLHALSVFLGNTHIQLRYSGAVLVDGKDIDLPWIAEGFNVSHASSTFLLLRWPGAWVLWGVADSAAYITLDPHHAYQVQGLCGTFTWKQQDDFLTPAGDIETSVAAFAGKFKVSGDGRCPWMDNIPLSACSTYSQRLVFAEAACAILHGPTFQECHGLVDRESFRLRCLEAVCGCAPGRNCLCSVLSAYARRCAQEGVLLQWRNETLCPILCPGGQAYQECAPMCGHHCGEPEECKELGGCVAGCNCPPGLLWAPEGQCVSPSMCPCQLGGHHYTFGTTTTTKDCSHCVCQERGLWNCTSNHCPPQRALCPQEFIYAPGACLLTCDSLSANHSCLAGSTDGCVCPPGTVLLDKRCVSPELCPCRHNGQWYPPNATIQEDCNICVCQGQRWHCTGQRCSGWCQASGAPHYVTFDGLVLTFPGACEYLLVREASGRFSVSIQNLPCGASGLTCTKALAVRLDGTVVHMLRGQAVTVNGVSIKLPKVYTGPGLSLHHAGIFLLLTTRLGLTLLWDGGTRVLVRLSPHFHGRVVGLCGDFDGDASNDLRSRQGVLEPTAELAAHSWRLNPLCPELGDLPHPCTVNTHRVNWAQARCGVILQPIFAPCHTEVPPQQHYEWCVYDACGCDTGGDCECLCSAIAAYADECARHRHHVRWRSQGLCPLQCEGGQVYEACGSTCPPTCHDHHPETRWQCQAISCVEGCFCPEGTLLHGGACVELPACPCEWDGSFFPPGTVLQKDCGNCTCQESRWHCGGDGVPCEEMKTGCAEGEALCRESGHCVPLEWLCDNQDDCGDGSDEEGCATSGCGEGQMSCQSGHCLPLALLCDGQDDCGDGTDEKGCPCPHGSLACADGRCLPPALLCNGHPDCLDAADEESCLGQLSCTSGEISCEDGTCIRARQLCDGVWDCPEGADEGPGHCPLPSLPTPPAGTWQSPSTSSLNTASSPMGSASPASPCGLFEFQCRSGECTPQGWRCDQEEDCPDASDELDCGGPCMLHQVPCAHSQHCLSPGQLCDGVPQCPDGSDEDPEACEGLSVPGGPNRTGVPCPEFSCPNGTCIDFLLVCDGNPDCELDNEAESSLEEQGCGAWSSWGPWEQCSQTCGPGVQGRSRHCSPSSLPVLKNCTGPQHQSQACFMEACPVDAEWSSWSPWSLCSEPCGGTMTRHRQCHPPQNGGQDCVLLPGSPRTTHQTNPCPQEGCPNATCFGELVFQPCAPCPLTCDDISDQTVCSPDRPCSSPGCWCPEGQVLGTDGRCLRPRQCPCLVNGTRYWPGQHIKVNCQLCLCQDGRPHRCRPNPECSVDCGWSSWSPWAECLGPCSSQSLQWSFRSPNNPRLSGRGRQCHGIHRKARRCQTEPCEGCEQWGLMHHVGERWRGGPCMVCECLHGGVTRCSLYCPLGSCPQGWVLVEGMGESCCHCALPGKNQTLAPRTTPAPASSPQIGAPLITYVLPPLGNACYSPLGLAQLPMWASSQHLEHPTWAAMGAPTTGPGPREDAYAEWHSQPLYLQMDLMQPRNLTGIMVQGVGSSAAYVASLSLQFSSDGLQWHDSVSSLPKSQPPPTLFPGSPSHMAPEVWTFNQMVQARYVRVWPHSGRHSDNIQHNIFLWVELLGLSPRTPACPENRHHCASGECVPKGGPCDGAVDCRDGSDDEACRPLRAGTTSRVHSTTRTPALSSTSTQPGTFPSQPREGVADMEHQQPKQEPSMPTAGAAGPIHASETPLPVSGKSMQMVTTISTFPPGAKSLNPGMAAVTALPPHSVTPVTPAGQSVTPWHFPPVWCSPGQLPCAVCTEAACDAGRKDCLGGSHEKHWATPGPFTIPTTALPELPASMTLCSPNQLSCGSGECLPREQRCDLQLNCQDGSDEDNCVDCVLAPWSVWSDCSHSCGLGLIFQRRELLRPPLPGGSCLLDQLRSQPCFMQACPVAGAWAEWGPWEPCSVSCGGGHQSRQRSCVDPPPKNGGAPCPGPSHERAPCSLQLCPGDTDCEPGLVHVNSELCQKGLVPPCPPSCLDPEANRSCNGQCMEGCRCPPGLFLQDSRCMPLSECPCLVGQDLRQPGLAFLLDNCSECMCEKGTLLCKSGGCSQSCGWSAWSPWTPCDHSCGSGVRARFRSPSNPPAAFGGTPCEGDRQELQACYTDCGAEIPGWTTWTPWSSCSQSCLVPEGDPGWRQRSRLCPSSRDTFCPGEATQEEPCSPPVCPVPSAWGLWASWSTCSASCNGGIQSRGRSCSSVAPGNPVCPGPHTQTRDCNMHPCTDQCPGNMVFRSAEQCHEEGGPCPQLCLAQDSGVECTGSCAPSCNCPPGLFLHNASCLPRSQCPCQLHGRLYAAGAVARLDCNNCTCVSGEMVCTAELCPVACGWSPWTPWSLCSQSCNVGIRRRFRAGTAPPAAFGGAECEGPNVDAEFCSLRPCQGPGAEWSSWSLCSVPCGGGYRNRTQGGGPHSPIEFSTCSLQPCAGPVPGVCPKGQQWLDCAQGPASCAHLSTHRETNQTCQPGCYCLSGMLLLNNVCVPAKDCPCTHRGRLHPPGSAVVHPCENCSCVSGLITNCSSWPCEEGQPAWSPWTPWSMCSASCSPAQRHRHRFCATPPRMEPFSQALLPTVAPTTHCPGSEAEEEPCLLPGCDQAGSWGPWGPWSGCSRSCGGGLRSRTRACDQPPPQGLGDFCEGPQAQGEACQSQPCPVTNCSTIEGAEYSHCGPPCPRSCDDLVHCVWHCQPGCYCPLGKVLSADGTICVQPSHCSCLDLLTGKRHHPGTQLTRPDGCNHCTCMEGRLHCTDLPCQVPGGWCPWSEWTACSQPCRGQTRTRSRACVCPAPQHGGAPCPEEAGETGMQHQREACPNPTACPVDGAWSPWGPWSSCDACLGQSLRSRVCSHPPTADGGRPCPGGHQQSRPCRDSSTLCTDCGGGQDLLPCGQPCPRSCQDLSLGSICLPGSEGCQSGCGCPPGQLSQDGLCVLPADCHCHFQPRAMGIPENQSRSAGSTLSSWESLEPGEVVTGPCDNCTCVAGILQCHEVPSCPGPGMWSSWGPWEKCSVSCGGGEQLRSRHCARPPCPGLARQSRACHIQVCRGCQVSQLYRACQPGEGCPFTCAHIAGQVACFSESCEEGCHCPEGTFQHRLACVQLFCTELWLTLSPRSQPSGSQSCVYQEMPPEAQVLPLFPQVSWELLHRLTALLLQELGVASTAPRTYPGLLEDEGQTLGPGDELAPGQMLQTVCGNCSCVHGKLSCSMEECSRVHGSFGPWSTWSPCSQPCGGLGTRTRTRQCVHPHPTLVPGGLSCHGPLQDLEYCFSPECPGAARSMVEPVTGLAGGWGPWSPWSPCSHSCTDPVHPTWRSRTRLCLGNCTVGDSLQERPCNLPSCTALDLCPGPGCGSRNCSWTSWAPWEPCSRSCGVGQQRRLRAYNPPGPGGHWCSDILTAYQERRFCNLRACPVPGGWSRWSPWSWCDRSCGGGRSLRSRSCSSPPPKNGGASCVGERHHVRSCNPMPCEEGCPAGMEIVSCANRCPHSCSDLQEGVMCQEDQACQLGCRCSQGFLEQDGGCVPVGHCECTDAQGRSWAPGSQHQNACNNCSCQAGQLSCSAQACPPPAYCAWSHWSAWSPCSHSCGPQGQQSRFRSSTSGSWALECQKEQSQSQFCPEAPCPPLCLHEDHPRALGDSWLQGECQQCSCTPEGVICRDTECAVPGGWTLWSSWSHCSVSCGGGSQVRTRSCMVLSPQHGSLPCQGPDTQTQPCGQQLCLQVLETCSWGAWGPCSHSCGTGLASRSGSCPCLLTEEDSMCNDTFSRLDTQACYLGPCQEDCIWSDWSSWTRCSCKVLVQQRYRHQGPAPGRAVGSAPCTRLDGHFRPCTIDNCSEDGCPPPFEFQACGSPCAGLCATHRSHQLCQDLPPCQPGCYCPKGLLEQAGGCILPEQCNCWHTSGEGTRVPLAPGDHLKLGCKECECRSGELQCSSQGCEGLLPLTEWSEWSPCGPCLPLSALAPASKTALEGHWPLNTSGLPQTSVTLLASEQYRHRLCLDPETGRPWTGDPALCTVPLSQQRLCPDPGVCNDTCQWGPWGPWSPCQVPCSGGFKLRWREARDSSGGECRGPWAQTESCNMGSCPGESCETRDTVFTLDCANQCPRSCADLWDGVQCLQGHCSPGCRCPPGQLVQDGHCVPISSCHCGLPSANGSWELAPTQVVQLDCHNCTCINGSLVCPYLQCPVVGPWSAWSQCSAACGGGTMVRHRSCEERPEGTPCQALDMLQWQECNLQACPECPPGQVLSTCATLCPSLCSHLQPGTICVREPCQLGCSCPGGQLLHNGTCLSPAACPCSQLSLPWGLTLPLEEQAQELPAGTVLTWNCTHCTCQGGAFICSSIDCQGCPPGEIWQHVAPGELGPCEKTCPEMNVTLSWSNCTKAQAPGCVCQPGHFRSQTGVCVPEDHCECWHHGRPHLPGSEWQEACDSCHCLHGKSICTRHCPSLTCAQGQVMMQEPGSCCPICQQDTLGMQEEEPASCQYLTELRNLTKGPCHLDQVEVSYCSGQCRSSTNVMTEEPYLQSQCDCCSYRLDPDSPVRILNLHCPDGHTEPVVLPVIHSCQCSVCQGGDFSKH", "length": 5185, "header": "tr|A0A9J7KCM9-1|A0A9J7KCM9_CRIGR Isoform 1 of SCO-spondin OS=Cricetulus griseus OX=10029 GN=Sspop PE=3 SV=1 CANONICAL=A0A9J7KCM9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1536, "start_aa": "Thr", "end_pos": 1536, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1536", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2370, "start_aa": "Thr", "end_pos": 2370, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2370", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCM9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCM9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766298", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766298", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCM9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM9" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCM9", 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"MEQSREVCYSCEESFMTDDKMMMSVGHGHFSEMKLAFHVPTVTCVAVKVLRMKKKNASLVEVSIMKSLQHPDIIKLFGMVQSRDTTYLMMEHTSQGDLRHILELGSLQESEARRLFTQILLAVQYCHVNHIAHRDIKANNILLNCRGNAKLSGFDLAAKVTPGQKLRDYCGTLLYCAPELLLEKAYDGCAADIWSLGVLLFLMVVGRFPFQDSSSEGVRRQILAANVRIPEHVSRDIFNVIVKMLMIKPHRRPTVDQILMCPMIREGKPHSPPMSTQKHPGTVSRGIVSTMTVMGYKSEEIIDSLRDQKYNQVMATYPILQHQSPGGDCGLEATNNKEVSVTKEVTITKEAAIIQDPTITQEEDMAHEVTMTLEKTTTKEMTMDDGVSMTQTESITEEETIIKHEDIILEATITMEETVAQVRTLTQERTITQEEAITHGQPEDALTRERTITQEVAITHGQPEDALTQERTITQEEAITHGQPEDAGPASSGNRRRSGWKRAKKIMVNCLRHLCCCCLPPAKRRHDSCKTLAPKTRDPAVTHRSRWGKYPLYSFFSCSPL", "length": 561, "header": "tr|A0A9J7KCN2-1|A0A9J7KCN2_CRIGR Isoform 1 of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=LOC107977720 PE=4 SV=1 CANONICAL=A0A9J7KCN2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H702-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2/entry#A0A9J7H702-1", "sequence": { "sequence": "MEQSREVCYSCEESFMTDDKMMMSVGHGHFSEMKLAFHVPTVTCVAVKVLRMKKKNASLVEVSIMKSLQHPDIIKLFGMVQSRDTTYLMMEHTSQGDLRHILELGSLQESEARRLFTQILLAVQYCHVNHIAHRDIKANNILLNCRGNAKLSGFDLAAKVTPGQKLRDYCGTLLYCAPELLLEKAYDGCAADIWSLGVLLFLMVVGRFPFQDSSSEGVRRQILAANVRIPEHVSRDIFNVIVKMLMIKPHRRPTVDQILMCPMIREGKPHSPPMSTQKHPGTVSRGIVSTMTVMGYKSEEIIDSLRDQKYNQVMATYPILQHQSPGGDCGLEATNNKEVSVTKEVTITKEAAIIQDPTITQEEDMAHEVTMTLEKTTTKEMTMDDGVSMTQTESITEEETIIKHEDIILEATITMEETVAQVRTLTQERTITQEEAITHGQPEDALTRERTITQEEAITHGQPEDAGPASSGNRRRSGWKRAKKIMVNCLRHLCCCCLPPAKRRHDSCKTLAPKTRDPAVTHRSRWGKYPLYSFFSCSPL", "length": 540, "header": "tr|A0A9J7H702-1|A0A9J7H702_CRIGR Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=LOC107977720 PE=4 SV=1 CANONICAL=A0A9J7KCN2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H7U7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2/entry#A0A9J7H7U7-1", "sequence": { "sequence": "MEQSREVCYSCEESFMTDDKMMMSVGHGHFSEMKLAFHVPTVTCVAVKVLRMKKKNASLVEVSIMKSLQHPDIIKLFGMVQSRDTTYLMMEHTSQGDLRHILELGSLQESEARRLFTQILLAVQYCHVNHIAHRDIKANNILLNCRGNAKLSGFDLAAKVTPGQKLRDYCGTLLYCAPELLLEKAYDGCAADIWSLGVLLFLMVVGRFPFQDSSSEGVRRQILAANVRIPEHVSRDIFNVIVKMLMIKPHRRPTVDQILMCPMIREGKPHSPPMSTQKHPGTVSRGIVSTMTVMGYKSEEIIDSLRDQKYNQVMATYPILQHQSPGGDCGLEATNNKEVSVTKEVTITKEAAIIQDPTITQEEDMAHEVTMTLEKTTTKEMTMDDGVSMTQTESITEEETIIKHEDIILEATITMEETVAQVRTLTQERTITQEEAITHGQPEDALTRERTITQEVAITHGQPEDALTQERTITQEEAITHGQPEDAGPASSGNRRRSGWKRAKKIMVNCLRHLCCCCLPPAKRRHDSCKTLAPKTRDPAVTHRSSSEEVQPQLRGL", "length": 557, "header": "tr|A0A9J7H7U7-1|A0A9J7H7U7_CRIGR Computationally mapped isoform of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=LOC107977720 PE=4 SV=1 CANONICAL=A0A9J7KCN2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KCN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2/entry#A0A9J7KCN2-1", "sequence": { "sequence": "MEQSREVCYSCEESFMTDDKMMMSVGHGHFSEMKLAFHVPTVTCVAVKVLRMKKKNASLVEVSIMKSLQHPDIIKLFGMVQSRDTTYLMMEHTSQGDLRHILELGSLQESEARRLFTQILLAVQYCHVNHIAHRDIKANNILLNCRGNAKLSGFDLAAKVTPGQKLRDYCGTLLYCAPELLLEKAYDGCAADIWSLGVLLFLMVVGRFPFQDSSSEGVRRQILAANVRIPEHVSRDIFNVIVKMLMIKPHRRPTVDQILMCPMIREGKPHSPPMSTQKHPGTVSRGIVSTMTVMGYKSEEIIDSLRDQKYNQVMATYPILQHQSPGGDCGLEATNNKEVSVTKEVTITKEAAIIQDPTITQEEDMAHEVTMTLEKTTTKEMTMDDGVSMTQTESITEEETIIKHEDIILEATITMEETVAQVRTLTQERTITQEEAITHGQPEDALTRERTITQEVAITHGQPEDALTQERTITQEEAITHGQPEDAGPASSGNRRRSGWKRAKKIMVNCLRHLCCCCLPPAKRRHDSCKTLAPKTRDPAVTHRSRWGKYPLYSFFSCSPL", "length": 561, "header": "tr|A0A9J7KCN2-1|A0A9J7KCN2_CRIGR Isoform 1 of non-specific serine/threonine protein kinase OS=Cricetulus griseus OX=10029 GN=LOC107977720 PE=4 SV=1 CANONICAL=A0A9J7KCN2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 161, "start_aa": "Thr", "end_pos": 161, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr161", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCN2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCN2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:107977720", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:107977720", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCN2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ], "pmid": "" }, { "name": "tau-protein kinase activity", "id": "GO:0050321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050321", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCN2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCN2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCN2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCN2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRI0-1", "G3GWJ3-1", "G3GYQ3-1", "A0A9J7GY39-1", "G3H3C3-1", "G3HAZ9-1", "G3HLS6-1", "G3HVB0-1", "G3HVN3-1", "G3I7I8-1", "G3ICC3-1", "G3IDN3-1", "G3IN30-1", "Q63980-1", "G3GY19-1", "G3GVI7-1", "G3GWN1-1", "A0A9J7FF35-1", "G3HBI7-1", "A0A9J7H2E9-1", "G3H3S6-1", "G3H8I4-1", "G3HCC1-1", "G3HER3-1", "G3HT38-1", "G3HZH7-1", "G3IFB6-1", "G3IKJ7-1", "G3H5L5-1", "G3IGI9-1", "G3HZ18-1", "G3I472-1", "G3HMY1-1", "G3HZU1-1", "G3I3E2-1", "G3I8T5-1", "G3I0W5-1", "G3IB29-1", "A0A9J7GIM1-1", "G3HEH4-1", "A0A9J7GES8-1", "A0A9J7F0J6-1", "G3HTW4-1", "G3HV08-1", "G3I3Z8-1", "G3I5H0-1", "A0A9J7FDV1-1", "G3GRR1-1", "G3GUA6-1", "G3GX92-1", "G3HY42-1", "A0A8C2QND0-1", "G3HXQ8-1", "G3I724-1", "A0A8C2M0A2-1", "A0A9J7K2S5-1", "A0A8C2MMZ5-1", "A0A8C2QH69-1", "A0A8C2QL63-1", "A0A9J7K953-1", "A0A9J7G3C1-1", "A0A9J7GFS3-1", "A0A9J7JBH0-1", "A0A9J7FGD3-1", "A0A9J7FKM1-1", "A0A9J7JKJ1-1", "A0A9J7G180-1", "A0A9J7JTL3-1", "A0A9J7GQ42-1", "A0A9J7EZ53-1", "A0A9J7J5Z8-1", "A0A9J7EVK4-1", "A0A9J7F0G6-1", "A0A9J7FCC7-1", "A0A9J7K3S4-1", "A0A9J7GAF4-1", "A0A9J7GBF4-1", "A0A8C2MTI7-1", "A0A9J7J1N3-1", "A0A9J7F4P4-1", "A0A9J7JNU2-1", "A0A9J7FZY8-1", "A0A9J7H3M5-1", "A0A9J7JJV6-1", "A0A9J7GJE4-1", "A0A8C2LY52-1", "A0A9J7H8U3-1", "A0A9J7F821-1", "A0A8C2N185-1", "A0A9J7KFV8-1", "A0A8C2MQM0-1", "A0A8C2N310-1", "A0A9J7J6H1-1", "A0A9J7H2P9-1", "A0A9J7H4N5-1", "A0A3L7GPC7-1", "A0A9J7H6V8-1", "A0A3L7HV37-1", "A0A8C2LTZ7-1", "A0A9J7K7D8-1", "A0A8C2LDU9-1", "A0A8C2LTW4-1", "A0A9J7JAM4-1", "A0A9J7JXM2-1", "A0A9J7JRJ8-1", "A0A8C2QEB8-1", "A0A3L7HKC4-1", "A0A8C2LI14-1", "A0A8C2QDX9-1", "A0A9J7G1D9-1", "A0A9J7F985-1", "A0A8C2MCX3-1", "A0A8C2MEU5-1", "A0A8C2MFN1-1", "A0A8C2MMI4-1", "A0A9J7JAB2-1", "A0A9J7G969-1", "A0A8C2MQ42-1", "A0A8C2MR08-1", "A0A8C2MUQ5-1", "A0A9J7FZA7-1", "A0A8C2N3C9-1", "A0A8C2N6L4-1", "A0A8C2N9X1-1", "A0A8C2QHF9-1", "A0A8C2QI80-1", "A0A8C2QKP7-1", "A0A9J7F842-1", "A0A9J7FFS7-1", "A0A9J7FI14-1", "A0A9J7FJ23-1", "A0A9J7JLH7-1", "A0A9J7G270-1", "A0A8C2MH43-1", "A0A9J7FZ18-1", "A0A9J7G368-1", "A0A9J7G6S5-1", "A0A9J7K1H4-1", "A0A9J7H2T6-1", "A0A9J7H3N1-1", "A0A9J7H8L4-1", "A0A9J7JIW6-1", "A0A9J7JRI3-1", "A0A061I9F9-1", "A0A061HUS7-1", "A0A061HVM6-1", "A0A061I033-1", "A0A061I8L6-1", "A0A8C2MQS3-1", "A0A9J7F0Y2-1", "A0A061ILI7-1", "A0A9J7EZ49-1", "A0A8C2M9B6-1", "A0A8C2ML15-1", "A0A8C2LY02-1", "A0A8C2LZT2-1", "A0A8C2M165-1", "A0A8C2M5G2-1", "A0A8C2M3Y9-1", "A0A8C2M5A7-1", "A0A8C2M6A3-1", "A0A8C2MBW2-1", "A0A9J7JYU7-1", "A0A8C2MJ02-1", "A0A9J7JQD1-1", "A0A8C2MMQ4-1", "A0A8C2MQ73-1", "A0A8C2MQL9-1", "A0A9J7KE81-1", "A0A9J7JPE2-1", "A0A8C2LMC9-1", "A0A3L7I870-1", "A0A3L7IB60-1", "A0A3L7IBX6-1", "A0A3L7ID00-1", "A0A3L7IEL5-1", "A0A3L7IER1-1", "A0A8C2L7R1-1", "A0A8C2LC89-1", "A0A8C2LCN7-1", "A0A8C2LDQ8-1", "A0A8C2LEI8-1", "A0A8C2LH99-1", "A0A8C2LHE9-1", "A0A9J7GAB0-1", "A0A8C2LK72-1", "A0A8C2LMJ0-1", "A0A8C2LPR4-1", "A0A8C2LQB2-1", "A0A8C2LVV5-1", "P50310-1", "A0A8C2N4W2-1", "A0A9J7F0N6-1", "A0A9J7F3R3-1", "A0A8C2MV78-1", "A0A8C2MYH0-1", "A0A9J7JHJ2-1", "A0A8C2N0J6-1", "A0A8C2N210-1", "A0A8C2N457-1", "A0A8C2N756-1", "A0A8C2QGY5-1", "A0A8C2QJ34-1", "A0A8C2QJA4-1", "A0A9J7KDV7-1", "A0A8C2QNX2-1", "A0A8C2QPB0-1", "A0A9J7EVN3-1", "A0A8C2M6E6-1", "A0A9J7F2L0-1", "A0A9J7F5B0-1", "A0A8C2LDE5-1", "A0A9J7JB60-1", "A0A9J7F927-1", "A0A9J7FLY5-1", "A0A9J7F8V5-1", "A0A9J7F8T0-1", "A0A9J7FBT0-1", "A0A9J7FD79-1", "A0A9J7K2Q7-1", "A0A3L7I1R2-1", "A0A9J7FS53-1", "A0A9J7G9D1-1", "A0A9J7GD76-1", "A0A9J7FN68-1", "A0A9J7FNF0-1", "A0A9J7FUL0-1", "A0A9J7FVR6-1", "A0A9J7FYY3-1", "A0A9J7FZH7-1", "A0A9J7FZW1-1", "A0A9J7G1H0-1", "A0A9J7G5N9-1", "A0A8C2LFT9-1", "A0A9J7GBI2-1", "A0A8C2MB66-1", "A0A8C2LQS5-1", "A0A9J7GF22-1", "A0A9J7GF59-1", "A0A9J7GG74-1", "A0A9J7GGP1-1", "A0A9J7GHB3-1", "A0A9J7GI33-1", "A0A9J7GIC4-1", "A0A9J7GIN7-1", "A0A9J7GIR8-1", "A0A9J7GMF3-1", "A0A9J7GPQ3-1", "A0A9J7JPI2-1", "A0A9J7H5D8-1", "A0A9J7JZS0-1", "A0A9J7H4T9-1", "A0A9J7K4N6-1", "A0A9J7K8Y1-1", "A0A8C2M187-1", "A0A9J7KC95-1", "A0A9J7GR29-1", "A0A9J7GX76-1", "A0A9J7GZH5-1", "A0A9J7H0E7-1", "A0A9J7H3E2-1", "A0A9J7H3L8-1", "A0A9J7H7J5-1", "A0A9J7H8W9-1", "A0A8C2LRT3-1", "A0A9J7JDU1-1", "A0A9J7JGG9-1", "A0A9J7JGQ1-1", "A0A9J7JPD7-1", "A0A9J7JPY1-1", "A0A9J7FC43-1", "A0A9J7JXX3-1", "A0A9J7EUQ5-1", "A0A9J7EXX8-1", "A0A8C2MSQ2-1", "A0A9J7F1D2-1", "A0A9J7F2F1-1", "A0A9J7F383-1", "A0A8C2LPE9-1", "A0A9J7F9C4-1", "A0A9J7FC95-1", "A0A8C2M1F6-1", "A0A9J7FF13-1", "A0A9J7FGF7-1", "A0A9J7FKM9-1", "A0A8C2M7I3-1", "A0A8C2N3I1-1", "A0A8C2LVR4-1", "A0A3L7GMP6-1", "A0A9J7JQZ1-1", "A0A3L7HK04-1", "A0A3L7I4E3-1", "A0A3L7I1E7-1", "A0A9J7GBL6-1", "A0A9J7FN24-1", "A0A9J7FYJ6-1", "A0A9J7G4B8-1", "A0A9J7G8N0-1", "A0A9J7G8N4-1", "A0A9J7H540-1", "A0A9J7H949-1", "A0A9J7H3S8-1", "A0A9J7H401-1", "A0A9J7H503-1", "A0A9J7KCN2-1", "A0A9J7H7W6-1", "A0A9J7H8E3-1", "A0A9J7H8W5-1", "A0A9J7GF26-1", "A0A9J7GHK2-1", "A0A9J7GHV2-1", "A0A9J7GK55-1", "A0A9J7GLT3-1", "A0A9J7GMK5-1", "A0A9J7GP29-1", "A0A9J7GQY0-1", "A0A9J7GR05-1", "A0A9J7GRB5-1", "A0A9J7GRC1-1", "A0A8C2M6X8-1", "A0A9J7GTU0-1", "A0A9J7GVC9-1", "A0A9J7H0W8-1", "A0A9J7H1I4-1", "A0A9J7H241-1", "A0A3L7I5Y4-1", "A0A9J7JPF2-1", "A0A9J7JU24-1", "A0A9J7JNT2-1", "A0A9J7JSB5-1", "A0A9J7JTJ0-1", "A0A9J7K3L1-1", "A0A9J7K6R5-1", "A0A9J7KB54-1", "A0A9J7K851-1", "A0A9J7KCM5-1", "A0A9J7HEQ9-1", "A0A9J7J6E9-1", "A0A9J7J728-1", "A0A9J7JA07-1", "A0A3L7HMX8-1", "A0A061HZ27-1", "A0A9J7K7C7-1", "A0A061IJA8-1", "A0A8C2LA64-1", "A0A8C2LE67-1", "A0A8C2LII0-1", "A0A8C2LTD1-1", "A0A8C2M4R2-1", "A0A8C2MC09-1", "A0A8C2MCI5-1", "A0A8C2MP62-1", "A0A8C2N3U2-1", "A0A8C2M4P9-1", "A0A8C2QHS8-1", "A0A8C2QIA1-1", "A0A8C2QMB3-1", "A0A9J7F8T9-1", "A0A9J7FN52-1", "O55076-1", "P68180-1", "A0A061IJW6-1", "A0A3L7HQF4-1", "A0A3L7HRZ8-1", "A0A8C2LI15-1", "A0A8C2M497-1", "A0A8C2MAD7-1", "G3HBD4-1", "P25321-1", "A0A8C2MBP2-1", "A0A9J7JGR2-1", "A0A8C2QLT0-1", "A0A9J7JYC5-1" ], "evidence": [ { "id": "17989", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17989" } ] }, { "id": "46608", "name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRI0-1", "G3GWJ3-1", "G3GYQ3-1", "A0A9J7GY39-1", "G3H3C3-1", "G3HAZ9-1", "G3HLS6-1", "G3HVB0-1", "G3HVN3-1", "G3I7I8-1", "G3ICC3-1", "G3IDN3-1", "G3IN30-1", "Q63980-1", "G3GY19-1", "G3GVI7-1", "G3GWN1-1", "A0A9J7FF35-1", "G3HBI7-1", "A0A9J7H2E9-1", "G3H3S6-1", "G3H8I4-1", "G3HCC1-1", "G3HER3-1", "G3HT38-1", "G3HZH7-1", "G3IFB6-1", "G3IKJ7-1", "G3H5L5-1", "G3IGI9-1", "G3HZ18-1", "G3I472-1", "G3HMY1-1", "G3HZU1-1", "G3I3E2-1", "G3HX91-1", "G3I8T5-1", "G3I0W5-1", "G3IB29-1", "A0A9J7GIM1-1", "G3HEH4-1", "A0A9J7GES8-1", "A0A9J7F0J6-1", "G3HTW4-1", "G3HV08-1", "G3I3Z8-1", "G3I5H0-1", "A0A9J7FDV1-1", "G3GRR1-1", "G3GUA6-1", "G3GX92-1", "G3HY42-1", "A0A8C2QND0-1", "G3HXQ8-1", "A0A8C2M0A2-1", "A0A9J7K2S5-1", "A0A8C2MMZ5-1", "A0A8C2QH69-1", "A0A8C2QL63-1", "A0A9J7K953-1", "A0A9J7JBH0-1", "A0A9J7FEY2-1", "A0A9J7FGD3-1", "A0A9J7FKM1-1", "A0A9J7JKJ1-1", "A0A9J7G3C1-1", "A0A9J7G180-1", "A0A9J7JTL3-1", "A0A9J7GFS3-1", "A0A9J7GQ42-1", "A0A9J7EZ53-1", "A0A9J7J5Z8-1", "A0A9J7F0G6-1", "A0A9J7FCC7-1", "A0A9J7EVK4-1", "A0A9J7K3S4-1", "A0A9J7GAF4-1", "A0A9J7GBF4-1", "A0A8C2MTI7-1", "A0A9J7J1N3-1", "A0A9J7F4P4-1", "A0A9J7JNU2-1", "A0A9J7H3M5-1", "A0A9J7JJV6-1", "A0A9J7GJE4-1", "A0A8C2LY52-1", "A0A9J7H8U3-1", "A0A9J7F821-1", "A0A8C2N185-1", "A0A9J7KFV8-1", "A0A8C2MQM0-1", "A0A8C2N310-1", "A0A9J7H6V8-1", "A0A9J7H2P9-1", "A0A9J7H4N5-1", "A0A3L7GPC7-1", "A0A9J7J6H1-1", "A0A3L7HV37-1", "A0A8C2LTZ7-1", "A0A9J7K7D8-1", "A0A9J7JXM2-1", "A0A8C2LDU9-1", "A0A8C2LTW4-1", "A0A9J7JAM4-1", "A0A9J7JRJ8-1", "A0A8C2QEB8-1", "A0A3L7HKC4-1", "A0A8C2LI14-1", "A0A8C2QDX9-1", "A0A9J7G1D9-1", "A0A9J7F985-1", "A0A9J7G270-1", "A0A9J7K1H4-1", "A0A8C2MCX3-1", "A0A8C2MEU5-1", "A0A8C2MFN1-1", "A0A8C2MMI4-1", "A0A9J7JAB2-1", "A0A9J7G969-1", "A0A8C2MQ42-1", "A0A8C2MR08-1", "A0A8C2MUQ5-1", "A0A9J7FZA7-1", "A0A8C2N3C9-1", "A0A8C2N6L4-1", "A0A8C2N9X1-1", "A0A8C2QHF9-1", "A0A8C2QI80-1", "A0A8C2QKP7-1", "A0A9J7FFS7-1", "A0A9J7FI14-1", "A0A9J7FJ23-1", "A0A9J7JLH7-1", "A0A8C2MH43-1", "A0A9J7FZ18-1", "A0A9J7G368-1", "A0A9J7G6S5-1", "A0A9J7H2T6-1", "A0A9J7H3N1-1", "A0A9J7H8L4-1", "A0A9J7JIW6-1", "A0A9J7JRI3-1", "A0A061ILI7-1", "A0A061HUS7-1", "A0A061HVM6-1", "A0A061I033-1", "A0A061I8L6-1", "A0A061I9F9-1", "A0A8C2MQS3-1", "A0A9J7F0Y2-1", "A0A9J7EZ49-1", "A0A8C2M6A3-1", "A0A8C2MQL9-1", "A0A8C2LY02-1", "A0A8C2LZT2-1", "A0A8C2M165-1", "A0A8C2M5G2-1", "A0A8C2M3Y9-1", "A0A8C2M5A7-1", "A0A8C2M9B6-1", "A0A8C2MBW2-1", "A0A9J7JYU7-1", "A0A8C2MJ02-1", "A0A8C2ML15-1", "A0A9J7JQD1-1", "A0A8C2MMQ4-1", "A0A8C2MQ73-1", "A0A9J7KE81-1", "A0A9J7JPE2-1", "A0A9J7F773-1", "A0A8C2L7R1-1", "A0A8C2LHE9-1", "A0A3L7I870-1", "A0A3L7IB60-1", "A0A3L7IBX6-1", "A0A3L7ID00-1", "A0A3L7IEL5-1", "A0A3L7IER1-1", "A0A8C2LC89-1", "A0A8C2LCN7-1", "A0A8C2LEI8-1", "A0A8C2LH99-1", "A0A9J7GAB0-1", "A0A8C2LK72-1", "A0A8C2LMC9-1", "A0A8C2LMJ0-1", "A0A9J7JQV6-1", "A0A8C2LPR4-1", "A0A8C2LQB2-1", "A0A8C2LVV5-1", "A0A8C2MYH0-1", "A0A8C2MV78-1", "A0A9J7JHJ2-1", "A0A8C2N0J6-1", "A0A8C2N210-1", "A0A8C2N457-1", "A0A8C2N4W2-1", "A0A8C2N756-1", "A0A8C2QGY5-1", "A0A8C2QJ34-1", "A0A8C2QJA4-1", "A0A9J7KDV7-1", "A0A8C2QNX2-1", "A0A8C2QPB0-1", "A0A9J7EVN3-1", "A0A9J7F0N6-1", "A0A8C2M6E6-1", "A0A9J7F2L0-1", "A0A9J7F3R3-1", "A0A9J7F5B0-1", "A0A8C2LDE5-1", "A0A9J7JB60-1", "A0A9J7F927-1", "A0A9J7F8V5-1", "A0A9J7F8T0-1", "A0A9J7FBT0-1", "A0A9J7FD79-1", "A0A9J7FLY5-1", "A0A9J7K2Q7-1", "A0A3L7I1R2-1", "A0A9J7FYY3-1", "A0A9J7GBI2-1", "A0A9J7FN68-1", "A0A9J7FNF0-1", "A0A9J7FS53-1", "A0A9J7FUL0-1", "A0A9J7FVR6-1", "A0A9J7FZH7-1", "A0A9J7FZW1-1", "A0A9J7G1H0-1", "A0A9J7G5F3-1", "A0A9J7G5N9-1", "A0A8C2LFT9-1", "A0A9J7G9D1-1", "A0A8C2MB66-1", "A0A9J7GD76-1", "A0A8C2LQS5-1", "A0A9J7GF22-1", "A0A9J7GF59-1", "A0A9J7GG74-1", "A0A9J7GGP1-1", "A0A9J7GHB3-1", "A0A9J7GI33-1", "A0A9J7GIC4-1", "A0A9J7GIN7-1", "A0A9J7GIR8-1", "A0A9J7GMF3-1", "A0A9J7GPQ3-1", "A0A9J7JPI2-1", "A0A9J7H5D8-1", "A0A9J7JZS0-1", "A0A9J7H4T9-1", "A0A9J7K4N6-1", "A0A9J7K8Y1-1", "A0A8C2M187-1", "A0A9J7KC95-1", "A0A9J7GR29-1", "A0A9J7GT89-1", "A0A9J7GX76-1", "A0A9J7GZH5-1", "A0A9J7H0E7-1", "A0A9J7H3L8-1", "A0A9J7H7J5-1", "A0A9J7H8W9-1", "A0A8C2LRT3-1", "A0A9J7JDU1-1", "A0A9J7JGG9-1", "A0A9J7JGQ1-1", "A0A9J7JIF8-1", "A0A9J7JPD7-1", "A0A9J7JPY1-1", "A0A9J7F9C4-1", "A0A9J7FC43-1", "A0A9J7JXX3-1", "A0A9J7EUQ5-1", "A0A9J7EXX8-1", "A0A8C2MSQ2-1", "A0A9J7F1D2-1", "A0A9J7F2F1-1", "A0A9J7F383-1", "A0A8C2LPE9-1", "A0A9J7FC95-1", "A0A8C2M1F6-1", "A0A9J7FF13-1", "A0A9J7FGF7-1", "A0A9J7FKM9-1", "A0A8C2LVR4-1", "A0A3L7GMP6-1", "A0A8C2M7I3-1", "A0A8C2MBI9-1", "A0A9J7JQZ1-1", "A0A8C2N3I1-1", "A0A3L7HK04-1", "A0A3L7I4E3-1", "A0A9J7FN24-1", "A0A9J7FYJ6-1", "A0A9J7G4B8-1", "A0A9J7G8N0-1", "A0A9J7G8N4-1", "A0A9J7GBL6-1", "A0A9J7H8W5-1", "A0A9J7H3S8-1", "A0A9J7H401-1", "A0A9J7H503-1", "A0A9J7H540-1", "A0A9J7KCN2-1", "A0A9J7H7W6-1", "A0A9J7H8E3-1", "A0A9J7H949-1", "A0A9J7GQY0-1", "A0A9J7GF26-1", "A0A9J7GHK2-1", "A0A9J7GHV2-1", "A0A9J7GK55-1", "A0A9J7GLT3-1", "A0A9J7GMK5-1", "A0A9J7GP29-1", "A0A9J7GR05-1", "A0A9J7GRB5-1", "A0A9J7GRC1-1", "A0A8C2M6X8-1", "A0A9J7GTU0-1", "A0A9J7GVC9-1", "A0A9J7H0W8-1", "A0A9J7H1I4-1", "A0A9J7H241-1", "A0A3L7I5Y4-1", "A0A9J7K3L1-1", "A0A9J7JU24-1", "A0A9J7JNT2-1", "A0A9J7JPF2-1", "A0A9J7JSB5-1", "A0A9J7JTJ0-1", "A0A9J7K6R5-1", "A0A9J7K851-1", "A0A9J7KB54-1", "A0A9J7KCM5-1", "A0A9J7JA07-1", "A0A9J7HEQ9-1", "A0A9J7J6E9-1", "A0A9J7J728-1", "A0A9J7K7C7-1", "A0A061IJA8-1", "A0A3L7HMX8-1", "A0A8C2LA64-1", "A0A8C2LE67-1", "A0A8C2LII0-1", "A0A8C2LTD1-1", "A0A8C2LTT6-1", "A0A8C2M4R2-1", "A0A8C2MC09-1", "A0A8C2MCI5-1", "A0A8C2N3U2-1", "A0A8C2M4P9-1", "A0A8C2QHS8-1", "A0A8C2QIA1-1", "A0A8C2QMB3-1", "A0A9J7F8T9-1", "A0A9J7FN52-1", "O55076-1", "P68180-1", "A0A061IJW6-1", "A0A3L7HQF4-1", "A0A3L7HRZ8-1", "A0A8C2LI15-1", "A0A8C2M497-1", "A0A8C2MAD7-1", "G3HBD4-1", "P25321-1", "A0A8C2MBP2-1", "A0A9J7JGR2-1", "A0A8C2QLT0-1", "G3HDE8-1" ], "evidence": [ { "id": "46608", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/46608" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A061HUS7", "gene_name": "Srpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HUS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUS7" } ] } ] }, { "uniprot_ac": "A0A061HVM6", "gene_name": "Hipk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HVM6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVM6" } ] } ] }, { "uniprot_ac": "A0A061HZ27", "gene_name": "Pik3cg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A061HZ27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ27" } ] } ] }, { "uniprot_ac": "A0A061I033", "gene_name": "Mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A061I033", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I033" } ] } ] }, { "uniprot_ac": "A0A061I8L6", "gene_name": "Snrk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I8L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I8L6" } ] } ] }, { "uniprot_ac": "A0A061I9F9", "gene_name": "Stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061I9F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9F9" } ] } ] }, { "uniprot_ac": "A0A061IJA8", "gene_name": "Ripk2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A061IJA8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJA8" } ] } ] }, { "uniprot_ac": "A0A061IJW6", "gene_name": "Plk2", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A061IJW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJW6" } ] } ] }, { "uniprot_ac": "A0A061ILI7", "gene_name": "Cdkl2", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A061ILI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILI7" } ] } ] }, { "uniprot_ac": "A0A3L7GMP6", "gene_name": "Mapk7", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A3L7GMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GMP6" } ] } ] }, { "uniprot_ac": "A0A3L7GPC7", "gene_name": "Aurkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7GPC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GPC7" } ] } ] }, { "uniprot_ac": "A0A3L7HK04", "gene_name": "Csnk1g2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HK04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK04" } ] } ] }, { "uniprot_ac": "A0A3L7HKC4", "gene_name": "Cdkl4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A3L7HKC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HKC4" } ] } ] }, { "uniprot_ac": "A0A3L7HMX8", "gene_name": "Nek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HMX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMX8" } ] } ] }, { "uniprot_ac": "A0A3L7HQF4", "gene_name": "Eif2ak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HQF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQF4" } ] } ] }, { "uniprot_ac": "A0A3L7HRZ8", "gene_name": "Map3k13", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A3L7HRZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRZ8" } ] } ] }, { "uniprot_ac": "A0A3L7HV37", "gene_name": "Prpf4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7HV37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HV37" } ] } ] }, { "uniprot_ac": "A0A3L7I1E7", "gene_name": "Bckdk", "activity": [ { "ec_number": "2.7.11.-", "activity": "", "evidence": [ { "id": "A0A3L7I1E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1E7" } ] } ] }, { "uniprot_ac": "A0A3L7I1R2", "gene_name": "Riok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I1R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I1R2" } ] } ] }, { "uniprot_ac": "A0A3L7I4E3", "gene_name": "Sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I4E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E3" } ] } ] }, { "uniprot_ac": "A0A3L7I5Y4", "gene_name": "Plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A3L7I5Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I5Y4" } ] } ] }, { "uniprot_ac": "A0A3L7I870", "gene_name": "Tssk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7I870", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I870" } ] } ] }, { "uniprot_ac": "A0A3L7IB60", "gene_name": "Pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IB60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IB60" } ] } ] }, { "uniprot_ac": "A0A3L7IBX6", "gene_name": "Stk16", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IBX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IBX6" } ] } ] }, { "uniprot_ac": "A0A3L7ID00", "gene_name": "Stk17b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7ID00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7ID00" } ] } ] }, { "uniprot_ac": "A0A3L7IEL5", "gene_name": "LOC113833388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IEL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEL5" } ] } ] }, { "uniprot_ac": "A0A3L7IER1", "gene_name": "Stk38", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A3L7IER1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER1" } ] } ] }, { "uniprot_ac": "A0A8C2L7R1", "gene_name": "Map3k14", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2L7R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R1" } ] } ] }, { "uniprot_ac": "A0A8C2LA64", "gene_name": "Prkca", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LA64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA64" } ] } ] }, { "uniprot_ac": "A0A8C2LC89", "gene_name": "Map3k21", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LC89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC89" } ] } ] }, { "uniprot_ac": "A0A8C2LCN7", "gene_name": "Csnk2a2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LCN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCN7" } ] } ] }, { "uniprot_ac": "A0A8C2LDE5", "gene_name": "Prkci", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LDE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDE5" } ] } ] }, { "uniprot_ac": "A0A8C2LDQ8", "gene_name": "Vrk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LDQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDQ8" } ] } ] }, { "uniprot_ac": "A0A8C2LDU9", "gene_name": "Ern1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LDU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDU9" } ] } ] }, { "uniprot_ac": "A0A8C2LE67", "gene_name": "Prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LE67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE67" } ] } ] }, { "uniprot_ac": "A0A8C2LEI8", "gene_name": "Mos", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LEI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEI8" } ] } ] }, { "uniprot_ac": "A0A8C2LFT9", "gene_name": "Eif2ak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LFT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFT9" } ] } ] }, { "uniprot_ac": "A0A8C2LH99", "gene_name": "Pdpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LH99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH99" } ] } ] }, { "uniprot_ac": "A0A8C2LHE9", "gene_name": "Camk1d", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHE9" } ] } ] }, { "uniprot_ac": "A0A8C2LI14", "gene_name": "Mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI14" } ] } ] }, { "uniprot_ac": "A0A8C2LI15", "gene_name": "Stk25", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LI15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI15" } ] } ] }, { "uniprot_ac": "A0A8C2LII0", "gene_name": "Cdk6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2LII0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LII0" } ] } ] }, { "uniprot_ac": "A0A8C2LK72", "gene_name": "Rps6ka4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LK72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK72" } ] } ] }, { "uniprot_ac": "A0A8C2LMC9", "gene_name": "Mknk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMC9" } ] } ] }, { "uniprot_ac": "A0A8C2LMJ0", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LMJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMJ0" } ] } ] }, { "uniprot_ac": "A0A8C2LPE9", "gene_name": "Mast3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPE9" } ] } ] }, { "uniprot_ac": "A0A8C2LPR4", "gene_name": "Mapkapk5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LPR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPR4" } ] } ] }, { "uniprot_ac": "A0A8C2LQB2", "gene_name": "Pak5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQB2" } ] } ] }, { "uniprot_ac": "A0A8C2LQS5", "gene_name": "Rps6kb1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LQS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQS5" } ] } ] }, { "uniprot_ac": "A0A8C2LRT3", "gene_name": "Map3k5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2LRT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRT3" } ] } ] }, { "uniprot_ac": "A0A8C2LTD1", "gene_name": "Prkcb", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTD1" } ] } ] }, { "uniprot_ac": "A0A8C2LTT6", "gene_name": "Prkd2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2LTT6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT6" } ] } ] }, { "uniprot_ac": "A0A8C2LTW4", "gene_name": "Dclk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTW4" } ] } ] }, { "uniprot_ac": "A0A8C2LTZ7", "gene_name": "Tssk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LTZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTZ7" } ] } ] }, { "uniprot_ac": "A0A8C2LVR4", "gene_name": "LOC100775051", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LVR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR4" } ] } ] }, { "uniprot_ac": "A0A8C2LVV5", "gene_name": "Camk1g", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2LVV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVV5" } ] } ] }, { "uniprot_ac": "A0A8C2LY02", "gene_name": "Mapk11", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2LY02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY02" } ] } ] }, { "uniprot_ac": "A0A8C2LY52", "gene_name": "Dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2LY52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY52" } ] } ] }, { "uniprot_ac": "A0A8C2LZT2", "gene_name": "Uhmk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2LZT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZT2" } ] } ] }, { "uniprot_ac": "A0A8C2M0A2", "gene_name": "Mapk4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M0A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0A2" } ] } ] }, { "uniprot_ac": "A0A8C2M165", "gene_name": "Cdk4", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M165", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M165" } ] } ] }, { "uniprot_ac": "A0A8C2M187", "gene_name": "Map2k2", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2M187", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M187" } ] } ] }, { "uniprot_ac": "A0A8C2M1F6", "gene_name": "Cdk19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2M1F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M1F6" } ] } ] }, { "uniprot_ac": "A0A8C2M3Y9", "gene_name": "Aurka", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M3Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M3Y9" } ] } ] }, { "uniprot_ac": "A0A8C2M497", "gene_name": "Prkch", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M497", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M497" } ] } ] }, { "uniprot_ac": "A0A8C2M4P9", "gene_name": "Tesk1", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M4P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4P9" } ] } ] }, { "uniprot_ac": "A0A8C2M4R2", "gene_name": "Map3k20", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M4R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M4R2" } ] } ] }, { "uniprot_ac": "A0A8C2M5A7", "gene_name": "Clk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8C2M5A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5A7" } ] } ] }, { "uniprot_ac": "A0A8C2M5G2", "gene_name": "Map3k9", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2M5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M5G2" } ] } ] }, { "uniprot_ac": "A0A8C2M6A3", "gene_name": "Pnck", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M6A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6A3" } ] } ] }, { "uniprot_ac": "A0A8C2M6E6", "gene_name": "Mapk8", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2M6E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6E6" } ] } ] }, { "uniprot_ac": "A0A8C2M6X8", "gene_name": "Prkcq", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2M6X8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M6X8" } ] } ] }, { "uniprot_ac": "A0A8C2M7I3", "gene_name": "Camkk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8C2M7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M7I3" } ] } ] }, { "uniprot_ac": "A0A8C2M9B6", "gene_name": "Mapkapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2M9B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M9B6" } ] } ] }, { "uniprot_ac": "A0A8C2MAD7", "gene_name": "Pim1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MAD7" } ] } ] }, { "uniprot_ac": "A0A8C2MB66", "gene_name": "Gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MB66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MB66" } ] } ] }, { "uniprot_ac": "A0A8C2MBI9", "gene_name": "Tnk1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8C2MBI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBI9" } ] } ] }, { "uniprot_ac": "A0A8C2MBP2", "gene_name": "Rock2", "activity": [ { "ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8C2MBP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBP2" } ] } ] }, { "uniprot_ac": "A0A8C2MBW2", "gene_name": "Tp53rk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MBW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MBW2" } ] } ] }, { "uniprot_ac": "A0A8C2MC09", "gene_name": "Stk39", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MC09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC09" } ] } ] }, { "uniprot_ac": "A0A8C2MCI5", "gene_name": "Pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2MCI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCI5" } ] } ] }, { "uniprot_ac": "A0A8C2MCX3", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MCX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MCX3" } ] } ] }, { "uniprot_ac": "A0A8C2MEU5", "gene_name": "Mark4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MEU5" } ] } ] }, { "uniprot_ac": "A0A8C2MFN1", "gene_name": "Ikbkb", "activity": [ { "ec_number": "2.7.11.10", "activity": "L-seryl-[I-kappa-B protein] + ATP = O-phospho-L-seryl-[I-kappa-B protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] }, { "ec_number": "2.7.11.10", "activity": "", "evidence": [ { "id": "A0A8C2MFN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFN1" } ] } ] }, { "uniprot_ac": "A0A8C2MH43", "gene_name": "Map2k7", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2MH43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MH43" } ] } ] }, { "uniprot_ac": "A0A8C2MJ02", "gene_name": "Rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MJ02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJ02" } ] } ] }, { "uniprot_ac": "A0A8C2ML15", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2ML15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2ML15" } ] } ] }, { "uniprot_ac": "A0A8C2MMI4", "gene_name": "Riok1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMI4" } ] } ] }, { "uniprot_ac": "A0A8C2MMQ4", "gene_name": "Cdc42bpa", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMQ4" } ] } ] }, { "uniprot_ac": "A0A8C2MMZ5", "gene_name": "Nuak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MMZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ5" } ] } ] }, { "uniprot_ac": "A0A8C2MP62", "gene_name": "Pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A8C2MP62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MP62" } ] } ] }, { "uniprot_ac": "A0A8C2MQ42", "gene_name": "Cdkl5", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8C2MQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ42" } ] } ] }, { "uniprot_ac": "A0A8C2MQ73", "gene_name": "Mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2MQ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ73" } ] } ] }, { "uniprot_ac": "A0A8C2MQL9", "gene_name": "LOC100766643", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2MQL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQL9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QHS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHS8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QHS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QHS8" } ] } ] }, { "uniprot_ac": "A0A8C2QI80", "gene_name": "Mapk3", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QI80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QI80" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2QI80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QI80" } ] } ] }, { "uniprot_ac": "A0A8C2QIA1", "gene_name": "Prkce", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QIA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QIA1" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8C2QIA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QIA1" } ] } ] }, { "uniprot_ac": "A0A8C2QJ34", "gene_name": "Oxsr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QJ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJ34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QJ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QJ34" } ] } ] }, { "uniprot_ac": "A0A8C2QJA4", "gene_name": "Pak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QJA4", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A8C2QL63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QL63" } ] } ] }, { "uniprot_ac": "A0A8C2QLT0", "gene_name": "Nek9", "activity": [ { "ec_number": "2.7.11.38", "activity": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QLT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLT0" } ] }, { "ec_number": "2.7.11.38", "activity": "", "evidence": [ { "id": "A0A8C2QLT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QLT0" } ] } ] }, { "uniprot_ac": "A0A8C2QMB3", "gene_name": "Mapk1", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMB3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A8C2QMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QMB3" } ] } ] }, { "uniprot_ac": "A0A8C2QND0", "gene_name": "Sgk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QND0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QND0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QND0" } ] } ] }, { "uniprot_ac": "A0A8C2QNX2", "gene_name": "Taok3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QNX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8C2QNX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QNX2" } ] } ] }, { "uniprot_ac": "A0A8C2QPB0", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8C2QPB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPB0" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8C2QPB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QPB0" } ] } ] }, { "uniprot_ac": "A0A9J7EUQ5", "gene_name": "Stk32b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EUQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EUQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EUQ5" } ] } ] }, { "uniprot_ac": "A0A9J7EVK4", "gene_name": "Bmp2k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EVK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVK4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EVK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVK4" } ] } ] }, { "uniprot_ac": "A0A9J7EVN3", "gene_name": "LOC100754361", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVN3" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7EVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EVN3" } ] } ] }, { "uniprot_ac": "A0A9J7EXX8", "gene_name": "LOC113832238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EXX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXX8" } ] } ] }, { "uniprot_ac": "A0A9J7EZ49", "gene_name": "Prkg2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A9J7EZ49", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ49" } ] } ] }, { "uniprot_ac": "A0A9J7EZ53", "gene_name": "Map4k4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7EZ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZ53" } ] } ] }, { "uniprot_ac": "A0A9J7F0G6", "gene_name": "Camk2b", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0G6" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7F0G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0G6" } ] } ] }, { "uniprot_ac": "A0A9J7F0J6", "gene_name": "Hipk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0J6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0J6" } ] } ] }, { "uniprot_ac": "A0A9J7F0N6", "gene_name": "LOC100770091", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F0N6" } ] } ] }, { "uniprot_ac": "A0A9J7F0Y2", "gene_name": "Srpk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F0Y2", "database": 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} ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7F2F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2F1" } ] } ] }, { "uniprot_ac": "A0A9J7F2L0", "gene_name": "Ripk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F2L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2L0" } ] } ] }, { "uniprot_ac": "A0A9J7F383", "gene_name": "LOC113833167", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F383", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F383" } ] } ] }, { "uniprot_ac": "A0A9J7F3R3", "gene_name": "Braf", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F3R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3R3" } ] } ] }, { "uniprot_ac": "A0A9J7F4P4", "gene_name": "Tnni3k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F4P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F4P4" } ] } ] }, { "uniprot_ac": "A0A9J7F5B0", "gene_name": "Plk4", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A9J7F5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F5B0" } ] } ] }, { "uniprot_ac": "A0A9J7F773", "gene_name": "Pklr", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7F773", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F773" } ] } ] }, { "uniprot_ac": "A0A9J7F821", "gene_name": "Hipk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F821", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F821" } ] } ] }, { "uniprot_ac": "A0A9J7F842", "gene_name": "Pikfyve", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F842" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A9J7F842", "database": 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ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8T9" } ] } ] }, { "uniprot_ac": "A0A9J7F8V5", "gene_name": "Nek3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F8V5" } ] } ] }, { "uniprot_ac": "A0A9J7F927", "gene_name": "Map3k12", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7F927", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F927" } ] } ] }, { "uniprot_ac": "A0A9J7F985", "gene_name": "LOC118237656", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7F985", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F985" } ] } ] }, { "uniprot_ac": "A0A9J7F9C4", "gene_name": "Nek5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9C4" } ] } ] }, { "uniprot_ac": "A0A9J7FBT0", "gene_name": "Speg", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FBT0" } ] } ] }, { "uniprot_ac": "A0A9J7FC43", "gene_name": "Cdk15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FC43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC43" } ] } ] }, { "uniprot_ac": "A0A9J7FC95", "gene_name": "Lrrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FC95" } ] } ] }, { "uniprot_ac": "A0A9J7FCC7", "gene_name": "Csnk1g3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FCC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCC7" } ] } ] }, { "uniprot_ac": "A0A9J7FD79", "gene_name": "Map3k4", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FD79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FD79" } ] } ] }, { "uniprot_ac": "A0A9J7FDV1", "gene_name": "Cdk7", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7FDV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDV1" } ] } ] }, { "uniprot_ac": "A0A9J7FEY2", "gene_name": "Csnk1a1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FEY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEY2" } ] } ] }, { "uniprot_ac": "A0A9J7FF13", "gene_name": "Stk40", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF13" } ] } ] }, { "uniprot_ac": "A0A9J7FF35", "gene_name": "Mknk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FF35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF35" } ] } ] }, { "uniprot_ac": "A0A9J7FFS7", "gene_name": "Map3k7", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7FFS7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFS7" } ] } ] }, { "uniprot_ac": "A0A9J7FGD3", "gene_name": "Trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGD3" } ] } ] }, { "uniprot_ac": "A0A9J7FGF7", "gene_name": "LOC100751450", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FGF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGF7" } ] } ] }, { "uniprot_ac": "A0A9J7FI14", "gene_name": "Prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A0A9J7FI14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI14" } ] } ] }, { "uniprot_ac": "A0A9J7FJ23", "gene_name": "LOC100757928", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FJ23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ23" } ] } ] }, { "uniprot_ac": "A0A9J7FKM1", "gene_name": "Melk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7FKM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM1" } ] } ] }, { "uniprot_ac": "A0A9J7FKM9", "gene_name": "LOC113834545", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FKM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKM9" } ] } ] }, { "uniprot_ac": "A0A9J7FLY5", "gene_name": "Mapk15", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7FLY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLY5" } ] } ] }, { "uniprot_ac": "A0A9J7FN24", "gene_name": "Alpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN24" } ] } ] }, { "uniprot_ac": "A0A9J7FN52", "gene_name": "Prkaca", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A9J7FN52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN52" } ] } ] }, { "uniprot_ac": "A0A9J7FN68", "gene_name": "Mast1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FN68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN68" } ] } ] }, { "uniprot_ac": "A0A9J7FNF0", "gene_name": "Map4k2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FNF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FNF0" } ] } ] }, { "uniprot_ac": "A0A9J7FS53", "gene_name": "Ttk", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7FS53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FS53" } ] } ] }, { "uniprot_ac": "A0A9J7FUL0", "gene_name": "Smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FUL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FUL0" } ] } ] }, { "uniprot_ac": "A0A9J7FVR6", "gene_name": "Cit", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FVR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FVR6" } ] } ] }, { "uniprot_ac": "A0A9J7FYJ6", "gene_name": "Hunk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FYY3", "gene_name": "Pik3r4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FYY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYY3" } ] } ] }, { "uniprot_ac": "A0A9J7FZ18", "gene_name": "Ulk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7FZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZ18" } ] } ] }, { "uniprot_ac": "A0A9J7FZA7", "gene_name": "Limk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7FZA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FZA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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H(+).", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G5N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G5N9" } ] } ] }, { "uniprot_ac": "A0A9J7G6S5", "gene_name": "Trpm7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7G6S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G6S5" } ] } ] }, { "uniprot_ac": "A0A9J7G8N0", "gene_name": "LOC100770044", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7G8N0", "database": 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GF59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GF59" } ] } ] }, { "uniprot_ac": "A0A9J7GFS3", "gene_name": "Aak1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GFS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GFS3" } ] } ] }, { "uniprot_ac": "A0A9J7GG74", "gene_name": "Cdkl3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GG74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG74" } ] } ] }, { "uniprot_ac": "A0A9J7GGP1", "gene_name": "Map4k1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GGP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GGP1" } ] } ] }, { "uniprot_ac": "A0A9J7GHB3", "gene_name": "Map2k4", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GHB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHB3" } ] } ] }, { "uniprot_ac": "A0A9J7GHK2", "gene_name": "LOC100753695", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHK2" } ] } ] }, { "uniprot_ac": "A0A9J7GHV2", "gene_name": "LOC100773845", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GHV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHV2" } ] } ] }, { "uniprot_ac": "A0A9J7GI33", "gene_name": "Map3k10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GI33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GI33" } ] } ] }, { "uniprot_ac": "A0A9J7GIC4", "gene_name": "Stk26", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIC4" } ] } ] }, { "uniprot_ac": "A0A9J7GIM1", "gene_name": "Cdk16", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIM1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7GIM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIM1" } ] } ] }, { "uniprot_ac": "A0A9J7GIN7", "gene_name": "Eif2ak3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GIN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIN7" } ] } ] }, { "uniprot_ac": "A0A9J7GIR8", "gene_name": "Prkcg", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7GIR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIR8" } ] } ] }, { "uniprot_ac": "A0A9J7GJE4", "gene_name": "Stk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GJE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJE4" } ] } ] }, { "uniprot_ac": "A0A9J7GK55", "gene_name": "Aurkc", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GK55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK55" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GK55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GK55" } ] } ] }, { "uniprot_ac": "A0A9J7GLT3", "gene_name": "LOC113838166", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLT3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GLT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GLT3" } ] } ] }, { "uniprot_ac": "A0A9J7GMF3", "gene_name": "LOC103158537", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMF3" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A9J7GMF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMF3" } ] } ] }, { "uniprot_ac": "A0A9J7GMK5", "gene_name": "Sbk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMK5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GMK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GMK5" } ] } ] }, { "uniprot_ac": "A0A9J7GP29", "gene_name": "Stk32a", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP29" } ] } ] }, { "uniprot_ac": "A0A9J7GPQ3", "gene_name": "Pim2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GPQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPQ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GPQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPQ3" } ] } ] }, { "uniprot_ac": "A0A9J7GQ42", "gene_name": "Map3k1", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ42" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7GQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQ42" } ] } ] }, { "uniprot_ac": "A0A9J7GQY0", "gene_name": "Wnk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQY0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GQY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQY0" } ] } ] }, { "uniprot_ac": "A0A9J7GR05", "gene_name": "Alpk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR05" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GR05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR05" } ] } ] }, { "uniprot_ac": "A0A9J7GR29", "gene_name": "Ern2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GR29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GR29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GR29" } ] } ] }, { "uniprot_ac": "A0A9J7GRB5", "gene_name": "LOC113838167", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GRB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GRB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRB5" } ] } ] }, { "uniprot_ac": "A0A9J7GRC1", "gene_name": "LOC100764806", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GRC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GRC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRC1" } ] } ] }, { "uniprot_ac": "A0A9J7GT89", "gene_name": "LOC100774420", "activity": [ { "ec_number": "2.7.1.40", "activity": "ITP + pyruvate = IDP + phosphoenolpyruvate + H(+).", "evidence": [ { "id": "A0A9J7GT89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GT89" } ] }, { "ec_number": "2.7.1.40", "activity": "", "evidence": [ { "id": "A0A9J7GT89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GT89" } ] } ] }, { "uniprot_ac": "A0A9J7GTU0", "gene_name": "LOC100757707", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GTU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GTU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GTU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GTU0" } ] } ] }, { "uniprot_ac": "A0A9J7GVC9", "gene_name": "LOC100759146", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GVC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVC9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GVC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVC9" } ] } ] }, { "uniprot_ac": "A0A9J7GX76", "gene_name": "Dapk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GX76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GX76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX76" } ] } ] }, { "uniprot_ac": "A0A9J7GY39", "gene_name": "Akt1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GY39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY39" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GY39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY39" } ] } ] }, { "uniprot_ac": "A0A9J7GZH5", "gene_name": "Ripk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7GZH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7GZH5", "database": "UniProtKB", "url": 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{ "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JHJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHJ2" } ] } ] }, { "uniprot_ac": "A0A9J7JIF8", "gene_name": "Prkd1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A9J7JIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIF8" } ] } ] }, { "uniprot_ac": "A0A9J7JIW6", "gene_name": "Pkn1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP 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"ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD7" } ] } ] }, { "uniprot_ac": "A0A9J7JPE2", "gene_name": "Map4k3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPE2" } ] } ] }, { "uniprot_ac": "A0A9J7JPF2", "gene_name": "LOC100765388", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPF2" } ] } ] }, { "uniprot_ac": "A0A9J7JPI2", "gene_name": "Ksr1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JPI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPI2" } ] } ] }, { "uniprot_ac": "A0A9J7JPY1", "gene_name": "Rps6kc1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRI3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRI3" } ] } ] }, { "uniprot_ac": "A0A9J7JRJ8", "gene_name": "Mark3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JRJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JRJ8" } ] } ] }, { "uniprot_ac": "A0A9J7JSB5", "gene_name": "LOC113836186", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSB5" } ] } ] }, { "uniprot_ac": "A0A9J7JTJ0", "gene_name": "LOC113838440", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JTJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTJ0" } ] } ] }, { "uniprot_ac": "A0A9J7JTL3", "gene_name": "Cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7JTL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTL3" } ] } ] }, { "uniprot_ac": "A0A9J7JU24", "gene_name": "Camk2a", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A9J7JU24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU24" } ] } ] }, { "uniprot_ac": "A0A9J7JXM2", "gene_name": "Dcaf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JXM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXM2" } ] } ] }, { "uniprot_ac": "A0A9J7JXX3", "gene_name": "Map3k3", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "A0A9J7JXX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXX3" } ] } ] }, { "uniprot_ac": "A0A9J7JYC5", "gene_name": "Nme7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYC5" } ] } ] }, { "uniprot_ac": "A0A9J7JYU7", "gene_name": "Mink1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7JYU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYU7" } ] } ] }, { "uniprot_ac": "A0A9J7JZS0", "gene_name": "Dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A9J7JZS0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZS0" } ] } ] }, { "uniprot_ac": "A0A9J7K1H4", "gene_name": "LOC113837295", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K1H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K1H4" } ] } ] }, { "uniprot_ac": "A0A9J7K2Q7", "gene_name": "LOC100773089", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K2Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2Q7" } ] } ] }, { "uniprot_ac": "A0A9J7K2S5", "gene_name": "Cask", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K2S5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2S5" } ] } ] }, { "uniprot_ac": "A0A9J7K3L1", "gene_name": "LOC100755238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3L1" } ] } ] }, { "uniprot_ac": "A0A9J7K3S4", "gene_name": "Mast4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K3S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3S4" } ] } ] }, { "uniprot_ac": "A0A9J7K4N6", "gene_name": "Sik3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K4N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4N6" } ] } ] }, { "uniprot_ac": "A0A9J7K6R5", "gene_name": "Nek11", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K6R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6R5" } ] } ] }, { "uniprot_ac": "A0A9J7K7C7", "gene_name": "Gsk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7C7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7C7" } ] } ] }, { "uniprot_ac": "A0A9J7K7D8", "gene_name": "LOC100757073", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K7D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7D8" } ] } ] }, { "uniprot_ac": "A0A9J7K851", "gene_name": "Dclk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K851", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K851" } ] } ] }, { "uniprot_ac": "A0A9J7K8Y1", "gene_name": "Lmtk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7K8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K8Y1" } ] } ] }, { "uniprot_ac": "A0A9J7K953", "gene_name": "Cdkl1", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7K953", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K953" } ] } ] }, { "uniprot_ac": "A0A9J7KB54", "gene_name": "LOC118237737", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KB54", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KB54" } ] } ] }, { "uniprot_ac": "A0A9J7KC95", "gene_name": "Rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KC95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC95" } ] } ] }, { "uniprot_ac": "A0A9J7KCM5", "gene_name": "LOC113837018", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCM5" } ] } ] }, { "uniprot_ac": "A0A9J7KCN2", "gene_name": "LOC107977720", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KCN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCN2" } ] } ] }, { "uniprot_ac": "A0A9J7KDV7", "gene_name": "Cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0A9J7KDV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDV7" } ] } ] }, { "uniprot_ac": "A0A9J7KE81", "gene_name": "Nek4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KE81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE81" } ] } ] }, { "uniprot_ac": "A0A9J7KFV8", "gene_name": "Tssk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A9J7KFV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFV8" } ] } ] }, { "uniprot_ac": "G3GRI0", "gene_name": "Mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3GRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRI0" } ] } ] }, { "uniprot_ac": "G3GRR1", "gene_name": "Cdk10", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GRR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRR1" } ] } ] }, { "uniprot_ac": "G3GUA6", "gene_name": "Tlk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GUA6" } ] } ] }, { "uniprot_ac": "G3GVI7", "gene_name": "Map2k3", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "G3GVI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GVI7" } ] } ] }, { "uniprot_ac": "G3GWJ3", "gene_name": "Cdk8", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3GWJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWJ3" } ] } ] }, { "uniprot_ac": "G3GWN1", "gene_name": "LOC100755333", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3GWN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWN1" } ] } ] }, { "uniprot_ac": "G3GX92", "gene_name": "Camk1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "G3GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GX92" } ] } ] }, { "uniprot_ac": "G3GY19", "gene_name": "Dyrk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GY19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GY19" } ] } ] }, { "uniprot_ac": "G3GYQ3", "gene_name": "Tesk2", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3GYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GYQ3" } ] } ] }, { "uniprot_ac": "G3H3C3", "gene_name": "Nek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3C3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3C3" } ] } ] }, { "uniprot_ac": "G3H3S6", "gene_name": "Lats1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H3S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H3S6" } ] } ] }, { "uniprot_ac": "G3H5L5", "gene_name": "Rps6ka3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H5L5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H5L5" } ] } ] }, { "uniprot_ac": "G3H8I4", "gene_name": "Lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3H8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8I4" } ] } ] }, { "uniprot_ac": "G3HAZ9", "gene_name": "Dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HAZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HAZ9" } ] } ] }, { "uniprot_ac": "G3HBD4", "gene_name": "LOC100765914", "activity": [ { "ec_number": "2.7.4.6", "activity": "UDP + ATP = UTP + ADP.", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] }, { "ec_number": "2.7.4.6", "activity": "", "evidence": [ { "id": "G3HBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBD4" } ] } ] }, { "uniprot_ac": "G3HBI7", "gene_name": "Cdk17", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HBI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBI7" } ] } ] }, { "uniprot_ac": "G3HCC1", "gene_name": "Chek2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HCC1" } ] } ] }, { "uniprot_ac": "G3HDE8", "gene_name": "Pck2", "activity": [ { "ec_number": "4.1.1.32", "activity": "ITP + oxaloacetate = IDP + phosphoenolpyruvate + CO2.", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] }, { "ec_number": "4.1.1.32", "activity": "", "evidence": [ { "id": "G3HDE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HDE8" } ] } ] }, { "uniprot_ac": "G3HEH4", "gene_name": "Clk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HEH4" } ] } ] }, { "uniprot_ac": "G3HER3", "gene_name": "Tssk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HER3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HER3" } ] } ] }, { "uniprot_ac": "G3HLS6", "gene_name": "Stk4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HLS6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HLS6" } ] } ] }, { "uniprot_ac": "G3HMY1", "gene_name": "Nim1k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HMY1" } ] } ] }, { "uniprot_ac": "G3HT38", "gene_name": "Mastl", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HT38", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HT38" } ] } ] }, { "uniprot_ac": "G3HTW4", "gene_name": "Cdk3", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HTW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HTW4" } ] } ] }, { "uniprot_ac": "G3HV08", "gene_name": "Cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HV08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HV08" } ] } ] }, { "uniprot_ac": "G3HVB0", "gene_name": "Dyrk1a", "activity": [ { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "G3HVB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVB0" } ] } ] }, { "uniprot_ac": "G3HVN3", "gene_name": "Raf1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HVN3" } ] } ] }, { "uniprot_ac": "G3HX91", "gene_name": "Prkd3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "G3HX91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HX91" } ] } ] }, { "uniprot_ac": "G3HXQ8", "gene_name": "Map3k8", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "G3HXQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HXQ8" } ] } ] }, { "uniprot_ac": "G3HY42", "gene_name": "Akt3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HY42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HY42" } ] } ] }, { "uniprot_ac": "G3HZ18", "gene_name": "LOC100756665", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZ18" } ] } ] }, { "uniprot_ac": "G3HZH7", "gene_name": "Pak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3HZH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZH7" } ] } ] }, { "uniprot_ac": "G3HZU1", "gene_name": "Mapk14", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "G3HZU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HZU1" } ] } ] }, { "uniprot_ac": "G3I0W5", "gene_name": "Stk38l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I0W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I0W5" } ] } ] }, { "uniprot_ac": "G3I3E2", "gene_name": "Pdik1l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3E2" } ] } ] }, { "uniprot_ac": "G3I3Z8", "gene_name": "Rps6kb2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I3Z8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I3Z8" } ] } ] }, { "uniprot_ac": "G3I472", "gene_name": "LOC100760228", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I472", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I472" } ] } ] }, { "uniprot_ac": "G3I5H0", "gene_name": "Cilk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "G3I5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3I5H0" } ] } ] }, { "uniprot_ac": "G3I724", "gene_name": 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CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. 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"categories": [ "Protein Classification" ] }, { "id": "IPR050831", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050831", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763744", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763744", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KCP1", "url": "https://www.orthodb.org/?gene=A0A9J7KCP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44427", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44427", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44427:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44427:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304999", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304999", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KCP1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KCP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCP1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDKYSMIPCKGCTLWQGLLLTASLLTCWYPPAIAQVTIESVPHRVVEGEDVLFLVHDLPSYILTLAWFKGEAIIDNGIAFYALGNEVRALGNLYSGRETMYRNGSLWIRNVTQADTGVYTLGILSGPREILSKTSMYLHVYSSHCECPSACAQPMIESVPPSVAEGESVLLVVHNLPENLEAFFWYKGAIVSRNKEVAGHRISINTTVFGSGHSGREIVYSNGSLLLQNVTWNDTGFYTLRTLTTDLKTEVLRVQLQLDTSRCVNHPASAHTTIESVPPSVAEGGSALLVVHNLPKDTRAIFWYKGAVAFKNQEVARRKIASKSSVLGPAHSGGETMYSNGSLLLQNVTRNDAGFYTLQTVTTDLKVGLVHVKLLVDTSSSVCCNSLTSVQLMIEPVPQNAVKGGIVLFLVHNLPEDLRAIAWYKSTYSMESSEVAVLNIPTNDITQGPAYSGRAVVYTNGSLLLQDVMESDAGVYTLQTLSRDFKTEKAQVQLHVYPCRLPPTNVQLSIETMPPHVVEGQSVLLLVHNIPENLRAFSWSKEVTTVSKEKIAINVITTNKSWLAPTHSGRVTMYPNGSLLLHNTIQKDAGFYIFNTLNTQFESQETHVYLHIYKPVTQPLIQINSTTVTEQSSVVLTCLSSDTEVSIRWIFNNRPLNLTKRMTLSRTKCQLRIDRVRRRNSGKYQCEVFNPVSSKTSLPVSLVVTYA", "length": 707, "header": "tr|A0A9J7KCP1-1|A0A9J7KCP1_CRIGR Isoform 1 of Carcinoembryonic antigen-related cell adhesion molecule 3 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100763744 PE=3 SV=1 CANONICAL=A0A9J7KCP1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KCP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCP1/entry#A0A9J7KCP1-1", "sequence": { "sequence": "MDKYSMIPCKGCTLWQGLLLTASLLTCWYPPAIAQVTIESVPHRVVEGEDVLFLVHDLPSYILTLAWFKGEAIIDNGIAFYALGNEVRALGNLYSGRETMYRNGSLWIRNVTQADTGVYTLGILSGPREILSKTSMYLHVYSSHCECPSACAQPMIESVPPSVAEGESVLLVVHNLPENLEAFFWYKGAIVSRNKEVAGHRISINTTVFGSGHSGREIVYSNGSLLLQNVTWNDTGFYTLRTLTTDLKTEVLRVQLQLDTSRCVNHPASAHTTIESVPPSVAEGGSALLVVHNLPKDTRAIFWYKGAVAFKNQEVARRKIASKSSVLGPAHSGGETMYSNGSLLLQNVTRNDAGFYTLQTVTTDLKVGLVHVKLLVDTSSSVCCNSLTSVQLMIEPVPQNAVKGGIVLFLVHNLPEDLRAIAWYKSTYSMESSEVAVLNIPTNDITQGPAYSGRAVVYTNGSLLLQDVMESDAGVYTLQTLSRDFKTEKAQVQLHVYPCRLPPTNVQLSIETMPPHVVEGQSVLLLVHNIPENLRAFSWSKEVTTVSKEKIAINVITTNKSWLAPTHSGRVTMYPNGSLLLHNTIQKDAGFYIFNTLNTQFESQETHVYLHIYKPVTQPLIQINSTTVTEQSSVVLTCLSSDTEVSIRWIFNNRPLNLTKRMTLSRTKCQLRIDRVRRRNSGKYQCEVFNPVSSKTSLPVSLVVTYA", "length": 707, "header": "tr|A0A9J7KCP1-1|A0A9J7KCP1_CRIGR Isoform 1 of Carcinoembryonic antigen-related cell adhesion molecule 3 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100763744 PE=3 SV=1 CANONICAL=A0A9J7KCP1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCP1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCP1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCP1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCP1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763744", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763744", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 233, "end_pos": 235, "annotation": 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"Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 615, "end_pos": 705, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 }, { "start_pos": 110, "end_pos": 112 }, { "start_pos": 205, "end_pos": 207 }, { "start_pos": 222, "end_pos": 224 }, { "start_pos": 229, "end_pos": 231 }, { "start_pos": 233, "end_pos": 235 }, { "start_pos": 340, "end_pos": 342 }, { "start_pos": 347, "end_pos": 349 }, { "start_pos": 460, "end_pos": 462 }, { "start_pos": 559, "end_pos": 561 }, { "start_pos": 576, "end_pos": 578 }, { "start_pos": 624, "end_pos": 626 }, { "start_pos": 657, "end_pos": 659 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 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"sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7KCP6-1", "uniprot_ac": "A0A9J7KCP6", "uniprot_id": "A0A9J7KCP6_CRIGR", "mass": { "chemical_mass": 108630.0, "monoisotopic_mass": 108630.0 }, "refseq": { "ac": "XP_035305017", "name": "LOW QUALITY PROTEIN: zinc finger protein 850-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305017" }, "gene_names": [ { "name": "LOC113838086", "type": "recommended", "evidence": [ { "id": "A0A9J7KCP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCP6" } ] }, { "name": "LOC113838086", "type": "synonym", "evidence": [ { "id": "XP_035305017", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305017" } ] } ], "protein_names": [ { "name": "LOW QUALITY PROTEIN: zinc finger protein 850-like", "type": "synonym", "evidence": [ { "id": "XP_035305017", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305017" }, { "id": "A0A9J7KCP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCP6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 2% of CDS bases internal stop codons :: corrected 2 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305017", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305017" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCP6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCP6#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCP6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCP6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113838086", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCP6", "locus": {} } ], "crossref": [ { "id": "113838086", "url": "https://www.ncbi.nlm.nih.gov/gene/113838086", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050758", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050758", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113838086", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113838086", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KCP6", "url": "https://www.orthodb.org/?gene=A0A9J7KCP6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305017", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305017", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KCP6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KCP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCP6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLENYSNLVSVGLSGSKPELVTCLEQYKEPWMVNIEDSEVLEPGTWPKKFSMSEVCDKTFTQSSTLQVHQKIHNGENPYKCKICGKSFKKASNLKVHQRIHTGEKPYKCSHCGKSFKRSTYLQVHQRIHTGEKPYKCSDCGKSFTFGSSLQVHQRIHTGEKPYKCSHCEKSFTNGSDLKVHQIIHTGEKHYKCSDCGKSFKRSTHLQVHQRIHSGEKPYKCLDCGKSFTIGSSLQVHQRLHTGEKPYKCLDCGKSFTDGSNLKVHQRIHTGEKLYKCSHCGKSFTVGSRLQVHQRIHTGEKPYKCSHCEKSFTNGSDLRVHQRIHTGEKPYKCSDCGKSFKISTHLKAHQRIHTGEKPYKCSDCGKSFKRRTHLQEHQRIHTGERPYKCSECGTSFKKSTHLQVHQNVHTRKKSYNCNVCGKSFMKDSNLQVHQKIHNGENPYKCKICGKSFKKASNLKVHQRIHTGEKPYKCSHCGKSFKRSTYLQVHQRIHTGEKPYKCSDCGKSFTFGSSLQVHQRIHTGEKPYKCSHCEKSFTNGSDLKVHQIIHTGEKHYKCSDCGKSFKRSTHLQVHQRIHSGEKPYKCLDCGKSFTIGSSLQVHQRLHTGEKPYKCLDCGKSFTDGSNLKVHQRIHTGEKLYKCSHCGKSFTVGSRLQVHQRIHTGEKPYKCSHCEKSFTNGSDLRVHQRIHTGEKPYKCSDCGKSFKISTHLKAHQRIHTGEKPYKCSDCGKSFKRRTHLQEHQRIHTGERPYKCSECGKTFTQSSTLPVHQKIHNGENPYKCKICGKSFKKASNLKVHQRIHTGEKPYKCSHCGKSFTDGSKLKVHQRIHTGEKPYKCSDCGKSFTDGSNLKVHKRIHTGEKPYKYSDCGKSFKRSMCLQLHQRIHTGEKPYKCSQCENSFTNGSDLQVHQRIHTGEKPYKXXDCGKSFSDGSNLKIHQRKHTGGKPYKW", "length": 949, "header": "tr|A0A9J7KCP6-1|A0A9J7KCP6_CRIGR Isoform 1 of LOW QUALITY PROTEIN: zinc finger protein 850-like OS=Cricetulus griseus OX=10029 GN=LOC113838086 PE=3 SV=1 CANONICAL=A0A9J7KCP6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KCP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCP6/entry#A0A9J7KCP6-1", "sequence": { "sequence": 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"tr|A0A9J7KCP6-1|A0A9J7KCP6_CRIGR Isoform 1 of LOW QUALITY PROTEIN: zinc finger protein 850-like OS=Cricetulus griseus OX=10029 GN=LOC113838086 PE=3 SV=1 CANONICAL=A0A9J7KCP6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCP6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCP6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCP6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCP6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:113838086", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113838086", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCP6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCP6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCP6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCP6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCP6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCP6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCP6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCP6" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCP6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCP6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { 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"sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7KCP9-1", "uniprot_ac": "A0A9J7KCP9", "uniprot_id": "A0A9J7KCP9_CRIGR", "mass": { "chemical_mass": 167335.0, "monoisotopic_mass": 167335.0 }, "refseq": { "ac": "XP_035304913", "name": "alpha-1-inhibitor 3 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304913" }, "gene_names": [ { "name": "LOC100760909", "type": "recommended", "evidence": [ { "id": "A0A9J7KCP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCP9" } ] }, { "name": "LOC100760909", "type": "synonym", "evidence": [ { "id": "XP_035304913", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304913" } ] } ], "protein_names": [ { "name": "Alpha-1-inhibitor 3 isoform X3", "type": "synonym", "evidence": [ { "id": "A0A9J7KCP9", "database": "UniProtKB", "url": 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This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304913", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304913" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCP9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCP9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100760909", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCP9", "locus": {} } ], "crossref": [ { "id": "cd02897", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02897", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100760909", "url": "https://www.ncbi.nlm.nih.gov/gene/100760909", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002890", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002890", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011625", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011625", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040839", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040839", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041555", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041555", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041813", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041813", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050473", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050473", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760909", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760909", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KCP9", "url": "https://www.orthodb.org/?gene=A0A9J7KCP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11412:SF133", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11412:SF133", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00207", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00207", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01835", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01835", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07677", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07677", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07678", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07678", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07703", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07703", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17789", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17789", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17791", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17791", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304913", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304913", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KCP9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KCP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCP9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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on a hybrid assembly strategy.", "journal": "Biotechnol. 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Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035301229", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301229" } ] }, { "annotation": "Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7H0A6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0A6#function" }, { "database": "UniProtKB", "id": "PIRNR005856", "url": "https://www.uniprot.org/uniprotkb/PIRNR005856#function" }, { "database": "UniProtKB", "id": "A0A9J7KCX4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCX4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Xrcc3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX4", "locus": {} } ], "crossref": [ { "id": "cd19491", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19491", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "103161145", "url": "https://www.ncbi.nlm.nih.gov/gene/103161145", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013632", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013632", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020588", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020588", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047348", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047348", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:103161145", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103161145", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KCX4", "url": "https://www.orthodb.org/?gene=A0A9J7KCX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46487", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46487", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46487:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46487:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08423", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08423", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035301229", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301229", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H0A6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0A6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H0A6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H0A6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KCX4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KCX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDLDQLDLNPRITAAIKKGRLRSVKEVLCYSGPDLQRLTSLSTHDVQHLLRVAALHLQGSRVLTALQLFQQRESFPEQHQRLSLGCPVLDQFLGGGLPLEGITDLAGRSSAGKTQLGLQLCLTVQFPRQYGGLEAGAVYICTEDAFPSKRLWQLIKQQQQLRTDVPGEVIQKIRFSNHIFIEHAADVDALLECVSKRVPILLSRGMARLVVVDSVAAPFRCEYDAQALATRAKHLQSLGAALRRLSSTFRSPVLCINQVGEAGETELTGKQLRWLLPLTLTWVFPGDGNGGGARVYAQATGVSMGTSTYWILEWGWDLQTAVPTLCLRAWDEHLSPALGITWANQILMRLMVDRAHEDDASMGLPRSPARTIRVLSAPHLPLSSCCYTVSAEGIRGIPGTESC", "length": 403, "header": "tr|A0A9J7KCX4-1|A0A9J7KCX4_CRIGR Isoform 1 of DNA repair protein OS=Cricetulus griseus OX=10029 GN=Xrcc3 PE=3 SV=1 CANONICAL=A0A9J7KCX4-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H0A6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX4/entry#A0A9J7H0A6-1", "sequence": { "sequence": "MDLDQLDLNPRITAAIKKGRLRSVKEVLCYSGPDLQRLTSLSTHDVQHLLRVAALHLQGSRVLTALQLFQQRESFPEQHQRLSLGCPVLDQFLGGGLPLEGITDLAGRSSAGKTQLGLQLCLTVQFPRQYGGLEAGAVYICTEDAFPSKRLWQLIKQQQQLRTDVPGEVIQKIRFSNHIFIEHAADVDALLECVSKRVPILLSRGMARLVVVDSVAAPFRCEYDAQALATRAKHLQSLGAALRRLSSTFRSPVLCINQVMETVEEQESMPRPLGAWDEHLSPALGITWANQILMRLMVDRAHEDDASMGLPRSPARTIRVLSAPHLPLSSCCYTVSAEGIRGIPGTESC", "length": 349, "header": "tr|A0A9J7H0A6-1|A0A9J7H0A6_CRIGR Computationally mapped isoform of DNA repair protein OS=Cricetulus griseus OX=10029 GN=Xrcc3 PE=3 SV=1 CANONICAL=A0A9J7KCX4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KCX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX4/entry#A0A9J7KCX4-1", "sequence": { "sequence": "MDLDQLDLNPRITAAIKKGRLRSVKEVLCYSGPDLQRLTSLSTHDVQHLLRVAALHLQGSRVLTALQLFQQRESFPEQHQRLSLGCPVLDQFLGGGLPLEGITDLAGRSSAGKTQLGLQLCLTVQFPRQYGGLEAGAVYICTEDAFPSKRLWQLIKQQQQLRTDVPGEVIQKIRFSNHIFIEHAADVDALLECVSKRVPILLSRGMARLVVVDSVAAPFRCEYDAQALATRAKHLQSLGAALRRLSSTFRSPVLCINQVGEAGETELTGKQLRWLLPLTLTWVFPGDGNGGGARVYAQATGVSMGTSTYWILEWGWDLQTAVPTLCLRAWDEHLSPALGITWANQILMRLMVDRAHEDDASMGLPRSPARTIRVLSAPHLPLSSCCYTVSAEGIRGIPGTESC", "length": 403, "header": "tr|A0A9J7KCX4-1|A0A9J7KCX4_CRIGR Isoform 1 of DNA repair protein OS=Cricetulus griseus OX=10029 GN=Xrcc3 PE=3 SV=1 CANONICAL=A0A9J7KCX4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCX4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCX4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:103161145", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103161145", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "Rad51C-XRCC3 complex", "id": "GO:0033065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033065", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCX4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCX4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX4" } ], "pmid": "" }, { "name": "replication fork", "id": "GO:0005657", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005657", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCX4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX4" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCX4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX4" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCX4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCX4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX4" } ], "pmid": "" }, { "name": "four-way junction DNA binding", "id": "GO:0000400", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000400", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCX4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX4" } ], "pmid": "" }, { "name": "ATP-dependent DNA damage sensor activity", "id": "GO:0140664", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140664", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCX4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "t-circle formation", "id": "GO:0090656", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090656", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCX4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX4" } ], "pmid": "" }, { "name": "telomere maintenance via recombination", "id": "GO:0000722", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000722", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCX4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX4" } ], "pmid": "" }, { "name": "resolution of mitotic recombination intermediates", "id": "GO:0071140", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071140", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCX4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX4" } ], "pmid": "" }, { "name": "double-strand break repair via synthesis-dependent strand annealing", "id": "GO:0045003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045003", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCX4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7KCX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX4" }, { "id": "PS50162", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50162" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RecA family profile 1", "eco_id": "ECO_0000259", "start_pos": 78, "end_pos": 259, "start_aa": "Gln", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7KCX6-1", "uniprot_ac": "A0A9J7KCX6", "uniprot_id": "A0A9J7KCX6_CRIGR", "mass": { "chemical_mass": 65665.0, "monoisotopic_mass": 65665.0 }, "refseq": { "ac": "XP_035305161", "name": "zinc finger protein 82 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305161" }, "gene_names": [ { "name": "LOC103164078", "type": "recommended", "evidence": [ { "id": "A0A9J7KCX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX6" } ] }, { "name": "LOC103164078", "type": "synonym", "evidence": [ { "id": "XP_035305161", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305161" } ] } ], "protein_names": [ { "name": "Zinc finger protein 30 homolog", "type": "recommended", "evidence": [ { "id": "A0A9J7KCX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX6/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 82 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035305161", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305161" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305161", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305161" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCX6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX6#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0A9J7H5F1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5F1#function" }, { "database": "UniProtKB", "id": "A0A9J7H6D5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6D5#function" }, { "database": "UniProtKB", "id": "A0A9J7H7J1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7J1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCX6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC103164078", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX6", "locus": {} } ], "crossref": [ { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "103164078", "url": "https://www.ncbi.nlm.nih.gov/gene/103164078", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:103164078", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103164078", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KCX6", "url": "https://www.orthodb.org/?gene=A0A9J7KCX6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381:SF435", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381:SF435", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305161", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305161", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7H5F1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5F1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H5F1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5F1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6D5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6D5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H6D5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H6D5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7J1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7J1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7J1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7J1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KCX6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KCX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPSSAPRKTELLLQWTMGLCSRHPQGGSQASVVTSVAMHVSVMFSDVSIAFSQEEWESLDLAQRDLYKDVMMENYRNVASLVGCFISKPDVISLLEQGKEPWKVVRKRRRNPDLETKDETNPSPSEGSIYEVNLSQWKIMERIGNSGLKGLIFKNEWESKRKLESQEGSQEGYLRQMKVTSEKMASYQIRTSATPHPRIHFGEKPYECDDCGKAFRVRQQLTFHQRIHTGEKPYGCKQCGMAFRQTAHLSRHQRLHSGDKPYECKECGEAFTYGPDLRAHQKTHSGEKPYACKECGKAFRVRGQLTLHQRIHTGEKPYACKECGRAFRQYAHLTRHQKLNSADRLYECKECGQDFLCGSGLRAHYRLHTGEKPYECQDCGKAFRVRQQLTLHQRTHTGEKPYECSECGKTFSRGYHLILHHRTHTGEKPYECKECWKAFSRYSQLISHQSVHIGVKPYDCKECGKAFRLLSQLTQHQSIHAGEKPYTCKDCGKSFRLRQKLTLHQSIHTGEKPFECKECRKAFRLNSSLIQHLRIHSGEKPYECKECKKAFRQHSHLTHHLKIHSAKV", "length": 568, "header": "tr|A0A9J7KCX6-1|A0A9J7KCX6_CRIGR Isoform 1 of Zinc finger protein 30 homolog OS=Cricetulus griseus OX=10029 GN=LOC103164078 PE=3 SV=1 CANONICAL=A0A9J7KCX6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7H5F1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX6/entry#A0A9J7H5F1-1", "sequence": { "sequence": "MARVSVMFSDVSIAFSQEEWESLDLAQRDLYKDVMMENYRNVASLVGCFISKPDVISLLEQGKEPWKVVRKRRRNPDLETKDETNPSPSEGSIYEVNLSQWKIMERIGNSGLKGLIFKNEWESKRKLESQEGSQEGYLRQMKVTSEKMASYQIRTSATPHPRIHFGEKPYECDDCGKAFRVRQQLTFHQRIHTGEKPYGCKQCGMAFRQTAHLSRHQRLHSGDKPYECKECGEAFTYGPDLRAHQKTHSGEKPYACKECGKAFRVRGQLTLHQRIHTGEKPYACKECGRAFRQYAHLTRHQKLNSADRLYECKECGQDFLCGSGLRAHYRLHTGEKPYECQDCGKAFRVRQQLTLHQRTHTGEKPYECSECGKTFSRGYHLILHHRTHTGEKPYECKECWKAFSRYSQLISHQSVHIGVKPYDCKECGKAFRLLSQLTQHQSIHAGEKPYTCKDCGKSFRLRQKLTLHQSIHTGEKPFECKECRKAFRLNSSLIQHLRIHSGEKPYECKECKKAFRQHSHLTHHLKIHSAKV", "length": 532, "header": "tr|A0A9J7H5F1-1|A0A9J7H5F1_CRIGR Computationally mapped isoform of Zinc finger protein 30 homolog OS=Cricetulus griseus OX=10029 GN=LOC103164078 PE=3 SV=1 CANONICAL=A0A9J7KCX6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H6D5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX6/entry#A0A9J7H6D5-1", "sequence": { "sequence": "MARVSVMFSDVSIAFSQEEWESLDLAQRDLYKDVMMENYRNVASLGCFISKPDVISLLEQGKEPWKVVRKRRRNPDLETKDETNPSPSEGSIYEVNLSQWKIMERIGNSGLKGLIFKNEWESKRKLESQEGSQEGYLRQMKVTSEKMASYQIRTSATPHPRIHFGEKPYECDDCGKAFRVRQQLTFHQRIHTGEKPYGCKQCGMAFRQTAHLSRHQRLHSGDKPYECKECGEAFTYGPDLRAHQKTHSGEKPYACKECGKAFRVRGQLTLHQRIHTGEKPYACKECGRAFRQYAHLTRHQKLNSADRLYECKECGQDFLCGSGLRAHYRLHTGEKPYECQDCGKAFRVRQQLTLHQRTHTGEKPYECSECGKTFSRGYHLILHHRTHTGEKPYECKECWKAFSRYSQLISHQSVHIGVKPYDCKECGKAFRLLSQLTQHQSIHAGEKPYTCKDCGKSFRLRQKLTLHQSIHTGEKPFECKECRKAFRLNSSLIQHLRIHSGEKPYECKECKKAFRQHSHLTHHLKIHSAKV", "length": 531, "header": "tr|A0A9J7H6D5-1|A0A9J7H6D5_CRIGR Computationally mapped isoform of Zinc finger protein 30 homolog OS=Cricetulus griseus OX=10029 GN=LOC103164078 PE=3 SV=1 CANONICAL=A0A9J7KCX6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H7J1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX6/entry#A0A9J7H7J1-1", "sequence": { "sequence": "MPSSAPRKTELLLQWTMGLCSRHPQGGSQASVVTSVAMHVSVMFSDVSIAFSQEEWESLDLAQRDLYKDVMMENYRNVASLGCFISKPDVISLLEQGKEPWKVVRKRRRNPDLETKDETNPSPSEGSIYEVNLSQWKIMERIGNSGLKGLIFKNEWESKRKLESQEGSQEGYLRQMKVTSEKMASYQIRTSATPHPRIHFGEKPYECDDCGKAFRVRQQLTFHQRIHTGEKPYGCKQCGMAFRQTAHLSRHQRLHSGDKPYECKECGEAFTYGPDLRAHQKTHSGEKPYACKECGKAFRVRGQLTLHQRIHTGEKPYACKECGRAFRQYAHLTRHQKLNSADRLYECKECGQDFLCGSGLRAHYRLHTGEKPYECQDCGKAFRVRQQLTLHQRTHTGEKPYECSECGKTFSRGYHLILHHRTHTGEKPYECKECWKAFSRYSQLISHQSVHIGVKPYDCKECGKAFRLLSQLTQHQSIHAGEKPYTCKDCGKSFRLRQKLTLHQSIHTGEKPFECKECRKAFRLNSSLIQHLRIHSGEKPYECKECKKAFRQHSHLTHHLKIHSAKV", "length": 567, "header": "tr|A0A9J7H7J1-1|A0A9J7H7J1_CRIGR Computationally mapped isoform of Zinc finger protein 30 homolog OS=Cricetulus griseus OX=10029 GN=LOC103164078 PE=3 SV=1 CANONICAL=A0A9J7KCX6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KCX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX6/entry#A0A9J7KCX6-1", "sequence": { "sequence": "MPSSAPRKTELLLQWTMGLCSRHPQGGSQASVVTSVAMHVSVMFSDVSIAFSQEEWESLDLAQRDLYKDVMMENYRNVASLVGCFISKPDVISLLEQGKEPWKVVRKRRRNPDLETKDETNPSPSEGSIYEVNLSQWKIMERIGNSGLKGLIFKNEWESKRKLESQEGSQEGYLRQMKVTSEKMASYQIRTSATPHPRIHFGEKPYECDDCGKAFRVRQQLTFHQRIHTGEKPYGCKQCGMAFRQTAHLSRHQRLHSGDKPYECKECGEAFTYGPDLRAHQKTHSGEKPYACKECGKAFRVRGQLTLHQRIHTGEKPYACKECGRAFRQYAHLTRHQKLNSADRLYECKECGQDFLCGSGLRAHYRLHTGEKPYECQDCGKAFRVRQQLTLHQRTHTGEKPYECSECGKTFSRGYHLILHHRTHTGEKPYECKECWKAFSRYSQLISHQSVHIGVKPYDCKECGKAFRLLSQLTQHQSIHAGEKPYTCKDCGKSFRLRQKLTLHQSIHTGEKPFECKECRKAFRLNSSLIQHLRIHSGEKPYECKECKKAFRQHSHLTHHLKIHSAKV", "length": 568, "header": "tr|A0A9J7KCX6-1|A0A9J7KCX6_CRIGR Isoform 1 of Zinc finger protein 30 homolog OS=Cricetulus griseus OX=10029 GN=LOC103164078 PE=3 SV=1 CANONICAL=A0A9J7KCX6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCX6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCX6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:103164078", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103164078", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCX6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCX6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCX6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX6" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCX6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCX6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 526, "end_pos": 528, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7KCX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX6" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 206, "end_pos": 233, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7KCX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCX6" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 114, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 133, "end_pos": 135 }, { "start_pos": 526, "end_pos": 528 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7KCY6-1", "uniprot_ac": "A0A9J7KCY6", "uniprot_id": "A0A9J7KCY6_CRIGR", "mass": { "chemical_mass": 17124.0, "monoisotopic_mass": 17124.0 }, "refseq": { "ac": "XP_035306835", "name": "LOW QUALITY PROTEIN: ubiquitin-conjugating enzyme E2 L3-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306835" }, "gene_names": [ { "name": "LOC100753227", "type": "recommended", "evidence": [ { "id": "A0A9J7KCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCY6" } ] }, { "name": "LOC100753227", "type": "synonym", "evidence": [ { "id": "XP_035306835", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306835" } ] } ], "protein_names": [ { "name": "E2 ubiquitin-conjugating enzyme", "type": "recommended", "evidence": [ { "id": "A0A9J7KCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCY6/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.23", "type": "synonym", "evidence": [ { "id": "A0A9J7KCY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCY6/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: ubiquitin-conjugating enzyme E2 L3-like", "type": "synonym", "evidence": [ { "id": "XP_035306835", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306835" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035306835", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306835" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KCY6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCY6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100753227", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCY6", "locus": {} } ], "crossref": [ { "id": "cd23801", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23801", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100753227", "url": "https://www.ncbi.nlm.nih.gov/gene/100753227", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000608", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000608", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753227", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753227", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KCY6", "url": "https://www.orthodb.org/?gene=A0A9J7KCY6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24068", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24068", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00179", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00179", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035306835", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306835", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KCY6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCY6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KCY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCY6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKEFEEIRKCGMKNFRNIQVDEANLMXWQGLIVPDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEEYSKDRKKFCKNAEEFTKKYGENRPVD", "length": 147, "header": "tr|A0A9J7KCY6-1|A0A9J7KCY6_CRIGR Isoform 1 of E2 ubiquitin-conjugating enzyme OS=Cricetulus griseus OX=10029 GN=LOC100753227 PE=3 SV=1 CANONICAL=A0A9J7KCY6-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KCY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KCY6/entry#A0A9J7KCY6-1", "sequence": { "sequence": "MKEFEEIRKCGMKNFRNIQVDEANLMXWQGLIVPDNPPYDKGAFRIEINFPAEYPFKPPKITFKTKIYHPNIDEKGQVCLPVISAENWKPATKTDQVIQSLIALVNDPQPEHPLRADLAEEYSKDRKKFCKNAEEFTKKYGENRPVD", "length": 147, "header": "tr|A0A9J7KCY6-1|A0A9J7KCY6_CRIGR Isoform 1 of E2 ubiquitin-conjugating enzyme OS=Cricetulus griseus OX=10029 GN=LOC100753227 PE=3 SV=1 CANONICAL=A0A9J7KCY6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305378", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305378" } ] }, { "annotation": "Calcium-regulated non-lysosomal thiol-protease.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KD31", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KD31#function" }, { "database": "UniProtKB", "id": "ARBA00002989", "url": "https://www.uniprot.org/uniprotkb/ARBA00002989#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KD31", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KD31" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Capn12", "url": 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"MASGNRKVTIQLVDDGAGAGARGPQLFKGQNYEAIRTACLESGILFRDPCFSAGPGALGYDKLGPDSEKAKGVEWKRPHVNCSNLPFLGFTGVLFPQEFCAEPQFICEDMSRTDVCQGSLGNCWLLAAAASLTLYPRLLYRVVPPGQSFQDGYAGVFHFQLWQFGRWVDVVVDDRLPVREGKLMFVRSEQRNEFWAPLLEKAYAKLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLRQNTPGLFAALRHALAKESLVGATALSDRGEIRTDEGLVKGHAYSVTGTNKMSLGFTKVRLLRLRNPWGRVEWSGPWSDSCPRWDMLPSEWRDALLVKKEDGEFWMELQDFLAHFNTVQICSLSPEVLGPSPAGGGWHIHTFQGRWVRGFNSGGSQPSAETFWTNPQFRLTLLEPDEEEDEDDEEGPWGGWGAAGARGPARGGRIPKCTVLLSLIQRNRRRLRAKGLTYLTVGFHVFQIPEELLGLWDSPRSRALLPRLLRADRSVFCARRDVSRRCRLPPGHYLVVPSATRVGDEADFTLRIFSERSHTAVEIDDVISADLEALEVSYKPLDLELAQLFLELAGEEEEINALQLQTLISIALEPASRANTRNPGEIGLRTCELLVQCFGHGQRLALHHFQELWGHLLVWQATFDKFDEDASGTMNSYELRLALNAAGFHLNNQLTQSLTSRYRDSRLRVDFERFVSCASRLTSIFRHCSRHLDGGEGVVCLTHKQWSEVATFS", "length": 739, "header": "tr|A0A9J7KD31-1|A0A9J7KD31_CRIGR Isoform 1 of Calpain-12 OS=Cricetulus griseus OX=10029 GN=Capn12 PE=3 SV=1 CANONICAL=A0A9J7KD31-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KD31-1", "url": 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KD31", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KD31" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767183", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767183", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium-dependent cysteine-type endopeptidase activity", "id": "GO:0004198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004198", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KD31", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KD31" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { 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"https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100751659", "url": "https://www.ncbi.nlm.nih.gov/gene/100751659", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751659", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751659", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KD52", "url": "https://www.orthodb.org/?gene=A0A9J7KD52", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11973", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11973", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11973:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11973:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08205", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08205", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305458", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305458", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KD52", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KD52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KD52-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KD52-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPPDARAGLLWLALLLAGHSGAQAEVHVSVPPLVEVLQGELITLDCKPRERPEHYVLEWFLVDASGSRHHLASVEPQGSELLSTVHNSRGRSPPYQLDSRGRLVIEKAQVGDERDYVCVVKAGSEGTSEATSRVRVFAIPEATEVIPNKGTLSVMEEFAQEIATCNSHNGNPVPRITWYRNGQRLDVPMEMKTDGYMTSRTVREASSLYSLTSTLYLKVYKEDRDAKFHCASHYKLPSNDHGRLDSPTFQLTLHYPTENVEFWVGSPSTTEGWVREGDAVQLFCQGDGSPSPEYSFFRIQDKQEKQLNVSLRGNFTLEGIRRNESGVYGCRVEDYDAPEEAQLVKSLELHVAYLDPLLLSVPEEVSVFLNSSDTVVDCSARGLPAPTVRWTKDSVTLANGPKLSLNSVTFDSAGTYTCEASTPIVPLLSRTQSFQLLVEGPPEIKPNEIKPISGNGWTEGDEVMLTCSARGYPEPKLTWTQRGHTPAETPSEGKGWRSSSMMVKVTSALSREGVSCEASNIHGKIEHVFHFGSVAPQTAQAGVAVMAVAVSVGLLLLVVAAFYCMRRKGRPGCCRRAEKGAPPAREPEMSHSGSDRPEQTGLLMGGPSFLLQPWPSLPSSXCWTGTHSGQRPQGGKEGGXGWEGAFLQGM", "length": 651, "header": "tr|A0A9J7KD52-1|A0A9J7KD52_CRIGR Isoform 1 of Basal cell adhesion molecule OS=Cricetulus griseus OX=10029 GN=Bcam PE=4 SV=1 CANONICAL=A0A9J7KD52-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KD52-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KD52/entry#A0A9J7KD52-1", "sequence": { "sequence": "MEPPDARAGLLWLALLLAGHSGAQAEVHVSVPPLVEVLQGELITLDCKPRERPEHYVLEWFLVDASGSRHHLASVEPQGSELLSTVHNSRGRSPPYQLDSRGRLVIEKAQVGDERDYVCVVKAGSEGTSEATSRVRVFAIPEATEVIPNKGTLSVMEEFAQEIATCNSHNGNPVPRITWYRNGQRLDVPMEMKTDGYMTSRTVREASSLYSLTSTLYLKVYKEDRDAKFHCASHYKLPSNDHGRLDSPTFQLTLHYPTENVEFWVGSPSTTEGWVREGDAVQLFCQGDGSPSPEYSFFRIQDKQEKQLNVSLRGNFTLEGIRRNESGVYGCRVEDYDAPEEAQLVKSLELHVAYLDPLLLSVPEEVSVFLNSSDTVVDCSARGLPAPTVRWTKDSVTLANGPKLSLNSVTFDSAGTYTCEASTPIVPLLSRTQSFQLLVEGPPEIKPNEIKPISGNGWTEGDEVMLTCSARGYPEPKLTWTQRGHTPAETPSEGKGWRSSSMMVKVTSALSREGVSCEASNIHGKIEHVFHFGSVAPQTAQAGVAVMAVAVSVGLLLLVVAAFYCMRRKGRPGCCRRAEKGAPPAREPEMSHSGSDRPEQTGLLMGGPSFLLQPWPSLPSSXCWTGTHSGQRPQGGKEGGXGWEGAFLQGM", "length": 651, "header": "tr|A0A9J7KD52-1|A0A9J7KD52_CRIGR Isoform 1 of Basal cell adhesion molecule OS=Cricetulus griseus OX=10029 GN=Bcam PE=4 SV=1 CANONICAL=A0A9J7KD52-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KD52", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KD52" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KD52", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KD52" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751659", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751659", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KD52", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KD52" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "laminin receptor activity", "id": "GO:0005055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005055", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KD52", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KD52" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 309, "end_pos": 311, "annotation": "n_glycosylation_sequon" }, { "start_pos": 315, "end_pos": 317, "annotation": "n_glycosylation_sequon" }, { "start_pos": 324, "end_pos": 326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 371, "end_pos": 373, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7KD52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KD52" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 25, "end_pos": 136, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 309, "end_pos": 311 }, { "start_pos": 315, "end_pos": 317 }, { "start_pos": 324, "end_pos": 326 }, { "start_pos": 371, "end_pos": 373 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7KD61-1", "uniprot_ac": "A0A9J7KD61", "uniprot_id": "A0A9J7KD61_CRIGR", "mass": { "chemical_mass": 11313.0, "monoisotopic_mass": 11313.0 }, "refseq": { "ac": "XP_035305493", "name": "cytochrome c oxidase subunit 7C, mitochondrial-like isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305493" }, "gene_names": [ { "name": "LOC100764831", "type": "recommended", "evidence": [ { "id": "A0A9J7KD61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KD61" } ] }, { "name": "LOC100764831", "type": "synonym", "evidence": [ { "id": "XP_035305493", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305493" } ] } ], "protein_names": [ { "name": "Cytochrome c oxidase subunit 7C, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A9J7KD61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KD61/entry#names_and_taxonomy" } ] }, { "name": "Cytochrome c oxidase polypeptide VIIc", "type": "synonym", "evidence": [ { "id": "A0A9J7KD61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KD61/entry#names_and_taxonomy" } ] }, { "name": "cytochrome c oxidase subunit 7C, mitochondrial-like isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035305493", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305493" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 25% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048603.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305493", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305493" } ] }, { "annotation": "Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). 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"MSRPSSRAIYLHRKEYSQSLASEPTLLQHRVEHLMTCKLGTQRVREPKDALQKLQEMDAQGRVWSQDLILQVKDGWLQLLDIETKEDLDSYRLDNIKAMDVALNTCSYNSILSVTVQESGLPATSTLLFQCQEVGAEQLRTSLQKALEEELEERPRFGVLHPGQDRRKEYPLERPIPIRQASPLEQRSPLEQRFPLERPPHMTPERSIPPSPRSLIQYPNAREPSDFTLPPPPRRAASPEDPGMDEEVLNHVLRDIELFAGKVKEAKAKDSHKKKKFGRKKNKAQNKITQAQYIDCFQKVKFSFNLLGKLALRLQETSAPEFVDLIFQTLKLILSQCPDTGLTAKVISPLLTPKAIDLLESCLRPPENALWKSLGLAWTTSWVDWTGSEPPPYRPTFYDGWQIPEPYSMEPLRHQNSISLRGSRMRSSLHFPQDEPYSHGSEHEDSNLPPSSPSPAKPVLKMQVLYEFEARNAQELTVAQGEILEVLDQSKRWWLVKNEAGQTGYIPSNILEPLPAGVPRSHRPSSFRAPMLRLSSKPAEVTAWLQAENFSTITVRTLGSLMGNQLLHMRFGELQMLCPQEASRIQARLDAVRRMLGDKWFPPHHTSHSFSLLLWFFLIPLLLSVVPQQYKPTDLSLVYSSHSRGNLRRISSAAAAEEVRTVRFQAPPEPRVRVRVAQ", "length": 678, "header": "tr|A0A9J7KD86-1|A0A9J7KD86_CRIGR Isoform 1 of Epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Eps8l3 PE=3 SV=1 CANONICAL=A0A9J7KD86-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KD86-1", "url": 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}, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"database": "UniProtKB", "id": "A0A9J7KD86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KD86" } ], "pmid": "" }, { "name": "vesicle", "id": "GO:0031982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031982", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KD86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KD86" } ], "pmid": "" }, { "name": "ruffle membrane", "id": "GO:0032587", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032587", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KD86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KD86" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "Rho protein signal transduction", "id": "GO:0007266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007266", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KD86", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KD86" } ], "pmid": "" }, { "name": "regulation of Rho protein signal transduction", "id": "GO:0035023", "url": 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"gene_names": [ { "name": "Ptprb", "type": "recommended", "evidence": [ { "id": "A0A9J7KDA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDA7" } ] }, { "name": "Ptprb", "type": "synonym", "evidence": [ { "id": "XP_035307251", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307251" } ] } ], "protein_names": [ { "name": "Receptor-type tyrosine-protein phosphatase beta", "type": "recommended", "evidence": [ { "id": "A0A9J7KDA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDA7/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.48", "type": "synonym", "evidence": [ { "id": "A0A9J7KDA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDA7/entry#names_and_taxonomy" } ] }, { "name": "Vascular endothelial protein tyrosine phosphatase", "type": "synonym", "evidence": [ { "id": "A0A9J7KDA7", "database": "UniProtKB", "url": 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This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307251", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307251" } ] }, { "annotation": "Plays an important role in blood vessel remodeling and angiogenesis. Not necessary for the initial formation of blood vessels, but is essential for their maintenance and remodeling. Can induce dephosphorylation of TEK/TIE2, CDH5/VE-cadherin and KDR/VEGFR-2. Regulates angiopoietin-TIE2 signaling in endothelial cells. Acts as a negative regulator of TIE2, and controls TIE2 driven endothelial cell proliferation, which in turn affects blood vessel remodeling during embryonic development and determines blood vessel size during perinatal growth. Essential for the maintenance of endothelial cell contact integrity and for the adhesive function of VE-cadherin in endothelial cells and this requires the presence of plakoglobin.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDA7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDA7#function" }, { "database": "UniProtKB", "id": "ARBA00059660", "url": "https://www.uniprot.org/uniprotkb/ARBA00059660#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDA7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDA7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ptprb", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDA7", "locus": {} } ], "crossref": [ { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14617", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14617", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100764837", "url": "https://www.ncbi.nlm.nih.gov/gene/100764837", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000242", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000242", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050713", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050713", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764837", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764837", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KDA7", "url": "https://www.orthodb.org/?gene=A0A9J7KDA7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46957", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46957", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46957:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46957:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00102", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00102", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00652", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00652", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18861", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18861", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307251", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307251", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10684", "url": "https://www.rhea-db.org/rhea/10684", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KDA7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KDA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDA7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAEVYMAILTCLILGNLEGFQIVHVRKQQCLSVNQKVIMGSCDGTSQNQQWLSTEDGKLFHIKSGSCLGISNSSRGPFRPAVSTPCAQAPRWTCHDQEGFLEVENTSLFLKKQNRKVVVRKISKYLDSWMKLDTNKEGKLVNESLCAKQAGLGTEVSVRIARNSAAPQIPTTFNTVPYSPEHIRNSTETFLRNTAGTYSQSSSKRYLHTAGTTDTSWSPSTTPPFLSTTTEAGLAELVRCNFTLLESRVSSVSASIQWRTLGSPCNFSLIYSSDTSLPMWCHPIRIDNITYGCNPKDLQAGTVYNFRIVSLDGEERTLVLQTDPLPPARFEVNPERTSSTTLQVRWTPSSGKVTWYEVQLFDDNNQKIQEVQAQESTTWSQYTFLNLTAGNNYKFAITAVSGEKRSFPMYTNGSTVPSPVKDIGISPNPNSLLISWSRGSGNVEQYRLMLVDKGILVQDRNVDKHDTSYTFYGLTPGHLYNLTIVTMASGLQNYKWKLVRTAPMEVSNLKVTNDASSTSLKVKWQKPLGDVDSYNITLSHQGTIKESKTLVPRVTETQFKDLVPGRLYQVTISCISGELSAQKMAMGRTVPEKVRNLVSYNEIWMKSFAVNWTPPAGDWEHYRVLLFNESLVLLNTTVGKEETHYVMDAVKLIPGREYEVEVVVESGNLRNSERCQGRTVPLAVLQLRVKHANETSLGITWQAPLGEWEKYIISLTDRDLLVIHKSLSKDAKDFTFMDLIPGRNYKATITSMSGDLKQSSSTKGRTVPAQVTDLHVTNQGMTSSLFTNWTKALGDVEFYQVLLIHENVVIKNESVSSETSRYSFHTLKSGSLYSVVVTTVSGGISSRQVVAEGRTVPSSVSGVTVNNSGRNDYLSVSWLPAPGDVDNYVVTLSHDGKVVQSLMIAKSVIECSFSSLTPGRLYNVTITTRSGNYASHSFGEERTVPDKVRGVSVSNSARSDYLKVSWVHATGDFDHYEVTIKNKNSFIQTKSIPKLENECVFVQLVPGRLYSVTVSTKSGQYEASEQENGRTIPEPVKDLTLRNRSTEDLHVTWSLANGDVDQYEVQLLFNDMKVFPPIHLVNTATEYRFTALTPGRHYKILVLTISGDVQQSAFIEGLTVPSAVKNIHISANGATDRLMVTWTPGGGDVDSYVVSAFRQEEKVQSQTVSKHISEYTFHRLEAGAKYRIAIASVSGSLSNQLDAPGQTVPAPVQGVVADNAYSSNSLTLSWQKAIGVAERYDILLLNENGVLLSNTSELATTKQHKFEDLTPGKKYKMHILTVSGGLFSKEAQAEGRTVPAAVTNLRITENSTRHLSFSWTASEGELSWYNIFLYNPDKTLQERAQVDPLVQSFSFQNLLQGRMYKLVIVTHSGELSNESFIFGRTVPAVVSHLKGSNRNMTDSLWFSWSPALGDFDFYELILYNPNGTKKENWRDKGLTEWRFQGLIPGRKYTLCVVTHSGDLTNKVTGEGRTAPSPPSLLSFADVANTSLAITWKGPPDWTDYNDFELQWFPRDALTVFNPYSNRKSEGRIVYGLRPGRSYQFSVKTVSGDSWKTYSKPISGSVRTKPDKIQNLHCRPQNSTAIACSWVPPDSDFDGYSVECRKMDTQEIEFSRNLEKEKSLLNIMMLVPHKRYLVSIKVQSAGVTSEVVEDSTITMIDRPPPPPPHIRVNEKEVLISKSSINFTVNCSWFSDTNGAVKYFAVVVREADGMDELKPEQQHPLPSYLEYRHNASIRVYQTNYFASKCAESPDSSSKSFNIKLGAEMDSLGGKCDPSQQKFCDGPLKPHTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSLPITTESEPLFGVIEGVSAGLFLIGMLVALVAFFICRQKVNHGRERPSAHLSIHRDRPLSVHLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEDLKDVGRNQPCDIALLPENRGKNRYNNILPYDTSRVKLSNVDDDPCSDYINASYIPGNNFRREYIATQGPLPGTKDDFWKMAWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMVSESVLPEWTIREFKICSEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFVALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYIYLHQCVRDVLRARKLRNEQENPLFPIYENVNPEYHRVDSNVRSARDSWEKQHYAIPGELPSEDSLSSKGFDASFSNTVTLQTKHLTVTDP", "length": 2259, "header": "tr|A0A9J7KDA7-1|A0A9J7KDA7_CRIGR Isoform 1 of Receptor-type tyrosine-protein phosphatase beta OS=Cricetulus griseus OX=10029 GN=Ptprb PE=3 SV=1 CANONICAL=A0A9J7KDA7-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KDA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDA7/entry#A0A9J7KDA7-1", "sequence": { "sequence": "MEAEVYMAILTCLILGNLEGFQIVHVRKQQCLSVNQKVIMGSCDGTSQNQQWLSTEDGKLFHIKSGSCLGISNSSRGPFRPAVSTPCAQAPRWTCHDQEGFLEVENTSLFLKKQNRKVVVRKISKYLDSWMKLDTNKEGKLVNESLCAKQAGLGTEVSVRIARNSAAPQIPTTFNTVPYSPEHIRNSTETFLRNTAGTYSQSSSKRYLHTAGTTDTSWSPSTTPPFLSTTTEAGLAELVRCNFTLLESRVSSVSASIQWRTLGSPCNFSLIYSSDTSLPMWCHPIRIDNITYGCNPKDLQAGTVYNFRIVSLDGEERTLVLQTDPLPPARFEVNPERTSSTTLQVRWTPSSGKVTWYEVQLFDDNNQKIQEVQAQESTTWSQYTFLNLTAGNNYKFAITAVSGEKRSFPMYTNGSTVPSPVKDIGISPNPNSLLISWSRGSGNVEQYRLMLVDKGILVQDRNVDKHDTSYTFYGLTPGHLYNLTIVTMASGLQNYKWKLVRTAPMEVSNLKVTNDASSTSLKVKWQKPLGDVDSYNITLSHQGTIKESKTLVPRVTETQFKDLVPGRLYQVTISCISGELSAQKMAMGRTVPEKVRNLVSYNEIWMKSFAVNWTPPAGDWEHYRVLLFNESLVLLNTTVGKEETHYVMDAVKLIPGREYEVEVVVESGNLRNSERCQGRTVPLAVLQLRVKHANETSLGITWQAPLGEWEKYIISLTDRDLLVIHKSLSKDAKDFTFMDLIPGRNYKATITSMSGDLKQSSSTKGRTVPAQVTDLHVTNQGMTSSLFTNWTKALGDVEFYQVLLIHENVVIKNESVSSETSRYSFHTLKSGSLYSVVVTTVSGGISSRQVVAEGRTVPSSVSGVTVNNSGRNDYLSVSWLPAPGDVDNYVVTLSHDGKVVQSLMIAKSVIECSFSSLTPGRLYNVTITTRSGNYASHSFGEERTVPDKVRGVSVSNSARSDYLKVSWVHATGDFDHYEVTIKNKNSFIQTKSIPKLENECVFVQLVPGRLYSVTVSTKSGQYEASEQENGRTIPEPVKDLTLRNRSTEDLHVTWSLANGDVDQYEVQLLFNDMKVFPPIHLVNTATEYRFTALTPGRHYKILVLTISGDVQQSAFIEGLTVPSAVKNIHISANGATDRLMVTWTPGGGDVDSYVVSAFRQEEKVQSQTVSKHISEYTFHRLEAGAKYRIAIASVSGSLSNQLDAPGQTVPAPVQGVVADNAYSSNSLTLSWQKAIGVAERYDILLLNENGVLLSNTSELATTKQHKFEDLTPGKKYKMHILTVSGGLFSKEAQAEGRTVPAAVTNLRITENSTRHLSFSWTASEGELSWYNIFLYNPDKTLQERAQVDPLVQSFSFQNLLQGRMYKLVIVTHSGELSNESFIFGRTVPAVVSHLKGSNRNMTDSLWFSWSPALGDFDFYELILYNPNGTKKENWRDKGLTEWRFQGLIPGRKYTLCVVTHSGDLTNKVTGEGRTAPSPPSLLSFADVANTSLAITWKGPPDWTDYNDFELQWFPRDALTVFNPYSNRKSEGRIVYGLRPGRSYQFSVKTVSGDSWKTYSKPISGSVRTKPDKIQNLHCRPQNSTAIACSWVPPDSDFDGYSVECRKMDTQEIEFSRNLEKEKSLLNIMMLVPHKRYLVSIKVQSAGVTSEVVEDSTITMIDRPPPPPPHIRVNEKEVLISKSSINFTVNCSWFSDTNGAVKYFAVVVREADGMDELKPEQQHPLPSYLEYRHNASIRVYQTNYFASKCAESPDSSSKSFNIKLGAEMDSLGGKCDPSQQKFCDGPLKPHTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSLPITTESEPLFGVIEGVSAGLFLIGMLVALVAFFICRQKVNHGRERPSAHLSIHRDRPLSVHLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEDLKDVGRNQPCDIALLPENRGKNRYNNILPYDTSRVKLSNVDDDPCSDYINASYIPGNNFRREYIATQGPLPGTKDDFWKMAWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMVSESVLPEWTIREFKICSEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFVALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYIYLHQCVRDVLRARKLRNEQENPLFPIYENVNPEYHRVDSNVRSARDSWEKQHYAIPGELPSEDSLSSKGFDASFSNTVTLQTKHLTVTDP", "length": 2259, "header": "tr|A0A9J7KDA7-1|A0A9J7KDA7_CRIGR Isoform 1 of Receptor-type tyrosine-protein phosphatase beta OS=Cricetulus griseus OX=10029 GN=Ptprb PE=3 SV=1 CANONICAL=A0A9J7KDA7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2115, "start_aa": "Thr", "end_pos": 2115, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2115", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDA7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDA7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDA7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDA7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764837", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764837", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "angiogenesis", "id": "GO:0001525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001525", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDA7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDA7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDA7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDA7" } ], "pmid": "" }, { "name": "receptor complex", "id": "GO:0043235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043235", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDA7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDA7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cadherin binding", "id": "GO:0045296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045296", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDA7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDA7" } ], "pmid": "" }, { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDA7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDA7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1044, "end_pos": 1046, "annotation": "n_glycosylation_sequon" }, { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1255, "end_pos": 1257, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1311, "end_pos": 1313, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1378, "end_pos": 1380, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1400, "end_pos": 1402, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1427, "end_pos": 1429, "annotation": "n_glycosylation_sequon" }, { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1489, "end_pos": 1491, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1582, "end_pos": 1584, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1685, "end_pos": 1687, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1689, "end_pos": 1691, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1733, "end_pos": 1735, "annotation": "n_glycosylation_sequon" }, { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1974, "end_pos": 1976, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2107, "end_pos": 2109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 267, "end_pos": 269, "annotation": "n_glycosylation_sequon" }, { "start_pos": 289, "end_pos": 291, "annotation": "n_glycosylation_sequon" }, { "start_pos": 387, "end_pos": 389, "annotation": "n_glycosylation_sequon" }, { "start_pos": 413, "end_pos": 415, "annotation": "n_glycosylation_sequon" }, { "start_pos": 482, "end_pos": 484, "annotation": "n_glycosylation_sequon" }, { "start_pos": 536, "end_pos": 538, "annotation": "n_glycosylation_sequon" }, { "start_pos": 612, "end_pos": 614, "annotation": "n_glycosylation_sequon" }, { "start_pos": 629, "end_pos": 631, "annotation": "n_glycosylation_sequon" }, { "start_pos": 636, "end_pos": 638, "annotation": "n_glycosylation_sequon" }, { "start_pos": 694, "end_pos": 696, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" }, { "start_pos": 789, "end_pos": 791, "annotation": "n_glycosylation_sequon" }, { "start_pos": 813, "end_pos": 815, "annotation": "n_glycosylation_sequon" }, { "start_pos": 867, "end_pos": 869, "annotation": "n_glycosylation_sequon" }, { "start_pos": 924, "end_pos": 926, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10684", "name": "", "equation": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3H060-1", "G3H622-1", "G3H9Q0-1", "A0A8C2LH05-1", "G3HKY7-1", "G3GWQ6-1", "G3HBF6-1", "G3GRD1-1", "G3H8H2-1", "A0A9J7FG56-1", "A0A061IAM9-1", "A0A9J7GE78-1", "A0A9J7GZK0-1", "A0A061HX98-1", 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"https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0A061IAM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAM9" } ] } ] }, { "uniprot_ac": "A0A3L7HAL2", "gene_name": "Pgp", "activity": [ { "ec_number": "3.1.3.21", "activity": "sn-glycerol 1-phosphate + H2O = glycerol + phosphate.", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] }, { "ec_number": "3.1.3.21", "activity": "", "evidence": [ { "id": "A0A3L7HAL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HAL2" } ] } ] }, { "uniprot_ac": "A0A3L7HEJ5", "gene_name": "Dusp2", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7HEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HEJ5" } ] } ] }, { "uniprot_ac": "A0A3L7I231", "gene_name": "Ptp4a3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7I231", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I231" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7I231", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I231" } ] } ] }, { "uniprot_ac": "A0A3L7IA07", "gene_name": "Ptp4a2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A3L7IA07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IA07" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A3L7IA07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IA07" } ] } ] }, { "uniprot_ac": "A0A8C2LH05", "gene_name": "Acp1", "activity": [ { "ec_number": "3.1.3.2", "activity": "a phosphate monoester + H2O = an alcohol + phosphate.", "evidence": [ { "id": "A0A8C2LH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH05" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH05" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2LH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH05" } ] }, { "ec_number": "3.1.3.2", "activity": "", "evidence": [ { "id": "A0A8C2LH05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LH05" } ] } ] }, { "uniprot_ac": "A0A8C2LVB9", "gene_name": "Dusp22", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LVB9", "database": 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{ "id": "A0A8C2LYZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYZ8" } ] } ] }, { "uniprot_ac": "A0A8C2MFV5", "gene_name": "LOC100758361", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFV5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2MFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFV5" } ] } ] }, { "uniprot_ac": "A0A8C2MQ28", "gene_name": "Ptprz1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MQ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ28" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2MQ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ28" } ] } ] }, { "uniprot_ac": "A0A8C2MZ43", "gene_name": "Ptprg", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MZ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ43" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2MZ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ43" } ] } ] }, { "uniprot_ac": "A0A8C2N2E5", "gene_name": "Dusp15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] } ] }, { "uniprot_ac": "A0A8C2N686", "gene_name": "Ptp4a1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N686", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N686" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2N686", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N686" } ] } ] }, { "uniprot_ac": "A0A8C2QC02", "gene_name": "Ptpn6", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QC02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC02" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QC02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC02" } ] } ] }, { "uniprot_ac": "A0A8C2QCP2", "gene_name": "Dusp28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2QCP2", "database": 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"evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] } ] }, { "uniprot_ac": "A0A9J7EXY7", "gene_name": "Ptpn13", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EXY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXY7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EXY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXY7" } ] } ] }, { "uniprot_ac": "A0A9J7EY47", "gene_name": "Cdkn3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] } ] }, { "uniprot_ac": "A0A9J7EZC9", "gene_name": "Ptpn18", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZC9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EZC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZC9" } ] } ] }, { "uniprot_ac": "A0A9J7EZL1", "gene_name": "LOC113830718", 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"url": "https://www.uniprot.org/uniprotkb/A0A9J7FEN1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FEN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEN1" } ] } ] }, { "uniprot_ac": "A0A9J7FEZ5", "gene_name": "Ptpn2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FEZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEZ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FEZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEZ5" } ] } ] }, { "uniprot_ac": "A0A9J7FG56", "gene_name": "Cdc25c", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FG56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FG56" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FG56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FG56" } ] } ] }, { "uniprot_ac": "A0A9J7FIV0", "gene_name": "LOC100763249", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FIV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FIV0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FIV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FIV0" } ] } ] }, { "uniprot_ac": "A0A9J7FKB3", "gene_name": "Pten", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": 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"https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] } ] }, { "uniprot_ac": "A0A9J7FMB0", "gene_name": "Dusp5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] } ] }, { "uniprot_ac": "A0A9J7FWJ6", "gene_name": "Dusp7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FWX7", "gene_name": "LOC103158664", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWX7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWX7" } ] } ] }, { "uniprot_ac": "A0A9J7FYL8", "gene_name": "Ptpn11", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FYL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYL8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FYL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYL8" } ] } ] }, { "uniprot_ac": "A0A9J7G003", "gene_name": "Ptprs", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G003", "database": 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"https://www.uniprot.org/uniprotkb/A0A9J7G1A0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G1A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1A0" } ] } ] }, { "uniprot_ac": "A0A9J7G7K2", "gene_name": "Ptpn1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G7K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7K2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G7K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7K2" } ] } ] }, { "uniprot_ac": "A0A9J7G7L1", "gene_name": "Ptprj", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G7L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7L1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G7L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7L1" } ] } ] }, { "uniprot_ac": "A0A9J7GBQ5", "gene_name": "LOC100764354", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GBQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GBQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ5" } ] } ] }, { "uniprot_ac": "A0A9J7GE78", "gene_name": "Dusp3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] } ] }, { "uniprot_ac": "A0A9J7GNR2", "gene_name": "Ptpn3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GNR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GNR2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GNR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GNR2" } ] } ] }, { "uniprot_ac": "A0A9J7GQC8", "gene_name": "LOC100757114", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GQC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQC8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GQC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQC8" } ] } ] }, { "uniprot_ac": "A0A9J7GQG9", "gene_name": "Ptprd", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GQG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQG9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GQG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQG9" } ] } ] }, { "uniprot_ac": "A0A9J7GX92", "gene_name": "Ptpre", 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}, "refseq": { "ac": "XP_035307291", "name": "von Willebrand factor D and EGF domain-containing protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307291" }, "gene_names": [ { "name": "Vwde", "type": "recommended", "evidence": [ { "id": "A0A9J7KDC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDC1" } ] }, { "name": "Vwde", "type": "synonym", "evidence": [ { "id": "XP_035307291", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307291" } ] } ], "protein_names": [ { "name": "von Willebrand factor D and EGF domain-containing protein", "type": "synonym", "evidence": [ { "id": "XP_035307291", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307291" }, { "id": "A0A9J7KDC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDC1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 5% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307291", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307291" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDC1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDC1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Vwde", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDC1", "locus": {} } ], "crossref": [ { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100765678", "url": "https://www.ncbi.nlm.nih.gov/gene/100765678", "database": "GeneID", "categories": [ "Genome 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"InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057885", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057885", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058727", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058727", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765678", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765678", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KDC1", "url": "https://www.orthodb.org/?gene=A0A9J7KDC1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14949", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14949", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14949:SF53", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14949:SF53", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00008", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00008", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23283", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23283", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25024", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25024", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26129", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26129", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307291", "url": 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"length": 1877, "header": "tr|A0A9J7KDC1-1|A0A9J7KDC1_CRIGR Isoform 1 of von Willebrand factor D and EGF domain-containing protein OS=Cricetulus griseus OX=10029 GN=Vwde PE=4 SV=1 CANONICAL=A0A9J7KDC1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KDC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDC1/entry#A0A9J7KDC1-1", "sequence": { "sequence": "MPGGTWTRLVTALMLLVLGEGQLAPECSPGGHQFLQSPYRSVYFDSVYFQQSAPQDLICDYSLTPGWYRFLIFDRPAEMPTKCIEMNHCGTQAPIWLSLSDSETLPLPGEIKQLTGCATWQLLFSTEMDCCLFQIPVFVRNCGDFFVYLLQPTQGCMGYCAEAISDVKLHACGPGEIEIGGDCIGQLSTVLPPPPPGRPQVTVELVGSQVFCRCAFDVPATNNSVGFLIAWFRLSSQGIKEELRQENTLQAFSLLELDGINLRLGDKIFCSASIFSLDKPEVQSIAVESQEYFAGIKLKPELSTISEDGKEYQLRVESTIPIVCSEFSELGQGCKISLKLRTTEQGKEHLGLNLALSSCHVDLHQNSSCDKGICSHAVVYYTAVTDFSQDGERITDITVEPIVSDDFLWDRYIPESIQIKVKDVPSAYCYSFTDPHIITFDGRVYDNFKTGTFVLYKSMSRDFEIHVRQWDCGRLHHPVSCNCGFVAKEEADIVTFDMCSGQLHESPPYLFVRNQDSSSSNIRITESYLGRKITVWLSSGAFIRADLSEWGMSITLRAPSLDYRNTLGLCGTFDENPENDFHDKNGIKIEDNVNNYIAFINEWRLLPGRSMFDKIPASRQFPAKPSYCSCLLGTASQRLLSNHLDRESHLEMAYSCKDLKHIQFSSLIPDLDITSKSISSEVLVRKISSHAPKKENNLNVLLQEKSHTNLTKLELNFQHPRNETQNPLKYFSNERHTQDRETRRNPQNRWKRQNLNAFLPMFAFQSLRQVNLEEFSYFFPEDHTEDNQQEFVSSWPTASGLTEPSILALCEQTLLNSSIGRLCLPFLGSTLNHVMDMCVKDVLLKDDVRWAEAGVALLENECERRVLEEGKHNIEEYRKSIGGILEALKCPNLCHGHGHCMDWGCACFPGYSSYDCSDSHDIGPEIIELENAGFCDIQKQNCVTVRVFGQGFKETSSIKCEVTKLEYDGSKWVPGVSVYTQTVFQDSGMVDCQLATDDRHSDTMDLMGEKSFAKLQLKVSNDGYTFSNPKIMTIYDGACQVCGPYEIDSCIMKDNICVIDGLCYTEGDKNPASSCLTCRPQISNSTWSFLDNNQPPVIQALQDKLQAFYGEDFEYQFMAWDLEGSEIHFTLDAGPDGAGVSSEGLLTWKTESLTPQRFILRLRDDCEAETTVTVEVTVKSCDCLNGGSCVSDRKFPSGSGAYLCVCLPGFHGNLCEVDASGCQSNPCGLGKCIRGLNTYSCDCPPELTGKNCEKDVDECESWPCFPGVECINIFGSYHCGSCPKGFHGDGNICHEWSIQSPSNEHLLSSPSFTQSPATNIYEFSHSIGTSNLTIKSVTAQMDSTTKVVSPQTPAHEYADHILSTNLTLKGLEIPAYTGTPNSSLGQINDAMQSTAQTETGGHDGPTRQPLQDFTQHEFTSLTTEEITILPEKFGSSKTSNCTESSCFPGVSCVPSIDGHLKCGRCPVGYYGDGINCRAFCRYSCGRNMECVAPNICKCKPGYTGSNCQTAICQPVCKKHGKCIKPNICECPPGHGGATCDEEYCSPPCQHGGTCLPGNLCTCAYGFVGPRCETLVCNRHCENGGECVAPDICQCKSGWNGPSCSTALCDPVCLNGGSCYKPNTCLCPDGFFGAQCQNAVCHPPCKNGGHCMRNNVCACRGGYTGKRCQKSICEPMCMNGGKCVGPNICSCASGWTGKWCNTPICLQKCKNGGECIAPSMCHCPSTWEGVQCEKPICAQKCLHGGKCAVPGVCSCRTGYSGVKCEKKIQVPDNANNRYRHLCVSSPWYLTTVNIYFQSKAYMDSIFASEEHISFYTPTNVLYSPNAVQRLCLTVQWDAGFQDSRGSYSTAGQRTQLIYALLKGNIRNPASPLTTSPPL", "length": 1877, "header": "tr|A0A9J7KDC1-1|A0A9J7KDC1_CRIGR Isoform 1 of von Willebrand factor D and EGF domain-containing protein OS=Cricetulus griseus OX=10029 GN=Vwde PE=4 SV=1 CANONICAL=A0A9J7KDC1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDC1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDC1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDC1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDC1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765678", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765678", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDC1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDC1" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDC1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDC1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDC1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDC1" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDC1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDC1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1084, "end_pos": 1086, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1331, "end_pos": 1333, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1365, "end_pos": 1367, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1381, "end_pos": 1383, "annotation": "n_glycosylation_sequon" }, 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"name": "Uncharacterized protein LOC113833395", "type": "synonym", "evidence": [ { "id": "A0A9J7KDD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDD8/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC113833395", "type": "synonym", "evidence": [ { "id": "XP_035307348", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307348" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 36% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307348", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307348" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDD8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDD8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113833395", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDD8", "locus": {} } ], "crossref": [ { "id": "A0A9J7KDD8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7KDD8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd09273", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09273", "database": "CDD", "categories": [ "Protein 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"length": 1097, "header": "tr|A0A9J7KDD8-1|A0A9J7KDD8_CRIGR Isoform 1 of Uncharacterized protein LOC113833395 OS=Cricetulus griseus OX=10029 GN=LOC113833395 PE=3 SV=1 CANONICAL=A0A9J7KDD8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KDD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDD8/entry#A0A9J7KDD8-1", "sequence": { "sequence": 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"length": 1097, "header": "tr|A0A9J7KDD8-1|A0A9J7KDD8_CRIGR Isoform 1 of Uncharacterized protein LOC113833395 OS=Cricetulus griseus OX=10029 GN=LOC113833395 PE=3 SV=1 CANONICAL=A0A9J7KDD8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDD8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDD8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDD8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDD8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:113833395", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113833395", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDD8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDD8" } ], "pmid": "" }, { "name": "RNA-DNA hybrid ribonuclease activity", "id": "GO:0004523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004523", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDD8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDD8" } ], "pmid": "" }, { "name": "nucleotidyltransferase activity", "id": "GO:0016779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016779", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDD8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDD8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA metabolic process", "id": "GO:0006259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006259", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDD8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDD8" } ], "pmid": "" }, { "name": "virion assembly", "id": "GO:0019068", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019068", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDD8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDD8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 952, "end_pos": 954, "annotation": 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"https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013548", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013548", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016201", "database": "InterPro", "categories": [ "Protein 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Classification", "Other" ] }, { "id": "PF08337", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08337", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17960", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17960", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18020", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18020", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20170", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20170", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24317", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24317", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24479", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24479", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305995", "url": 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"MEYLQHSPIRSHTDFFXAPVMAPWPLFILHLLLLPPLTRTHRFSVPNTRFNHLALAPGQGTLYVGAVNHLFQLSPELKMEAVAVTGPVIDSPDCVPFHDLAECPQAQLTDNANQLLLVSSRAQELVACGQVRQGVCEKRSLGDVAQVLYQAEDPGDGQFVAANIPGVTTVGLVVPLPGRDLLLVARGLAGKLSAGVPPLTVRQLAGPQPFSSEGLGRLVVGDFSDYNNSYVGAFADAHSAYFVFRRRGAQAQAEYHSYVARVCLGDVNLYSYVEVPLACHGQGLIQAAFLAPDTLLGAFAAGTSQAGAALCAFPLADLDNSMEQARRLCYTTGGQGPSGMEEATVEYGVTSRCVTLPPDSPESYPCGDEHTPSPIAGRQPLEAQPLLRLGQPISAVAALQADGHTIAFLGDTLGQLHKVFLNSSQGQIYHSQQVGPPGSAISPDLLIDNSGDHVYVLTAQQVDRILVAACPQFPNCTTCLQARDPLCGWCILQGRCTRRGECERAAQPNQWLWSYEDNYCLHIQSLLPAQHPRQEQGQISLSVPWLPTLAMDEYFHCAFGDYDSLAQVEGPHVVCVTPPGDQVPPNPPGSDHVTLPLALMFEDVVMAATTFSFYDCSAVQALEVASPCRTCVGSLWRCHWCPQSSHCVYGEHCPEGEKTVYSAQEVDIQVRGPGACPQVEGLASPQLVPVGWESHLALHIQNLHYFQGLPALYYCWLELPGKLQKLPASLEETSRDSGLIHCQAQQFHPSMSQRELPVPIYVTRGEIQRLDNAHDLHVTLYDCAVGHPDCSHCQAANGSLSCLWCGDGQPSCRYGPLCPPDAVEQLCPTPTIDMIEPLTGPPEGGLAITILGSNLGQAFNDVQNAVTVAGRPCSPDPSLYSISARIVCLTSPAPNGTAGPVQVAIKSRPPSISIQHFIYQDPVLLSLSPQWGPMSGGTQLTIHGQHLQTGGNVSAFVGDQPCLIQEPVCPEAIICHTMSQAEPGEAVVLVVFGHVERKLLTTPFRYTANPQLVAAEPSVSFRGGGRLIRVRGIGLDVVWQPLLSVWLEDEDQVKALGVQGQVVNPRRSCSAPAEDPQACILLESGLLQCSTLCSVNSSSLLLCHSPAVPDGALPKRVFFALDNMQVDFASASGGQGFLYQPNPRLVPLNHEGLAHPYRLKPGHVLDVEGEGLNLAISKEEVQVHIGDGECLVKTLTLTHLYCEPPLQAPQPTNGSGTLLQFVVQMGNVRLALGPVQYETESMTSTFPVEAQVGLGLGATVLIAAVLLLTLMYRHKSKQALRDYQKVLVQLENLETGVGDQCRKEFTDLMTEMTDLTSDLEASGIPFLDYRTYAERAFFPGYGGCPLKPGLEGPGEEGRRATVCQGLTQLSNLLNSKLFLLTLIHTLEEQPSFSQRDRCHVASLLSLALHSKLEYLTDIMRTLLGDLAAHYVHKNPKLMLRRTETMVEKLLTNWLSICLYAFLKEVAGEPLYMLFRAIKYQVDKGPVDAVTGKAKRTLNDSHLLREDVEFRPLTLMTLVGPGTYGTAGNSEVQRMPVRVLDTDTITQVKEKVLDQVYKGTPFSQRPSVHSLDLEWRSGLAGHLTLSDEDLTSVTQNHWKRLNTLQHYKVPDGATVVLIPQLHNGGTVSQRLGQTGCPFGENTPMLEDGEEGGVRLWHLVKATEEPEGAKVQRSNLRERERERARAKAIPEIYLTRLLSMKGTLQKFVDDTFQAILSVNRPVPIAVKYLFDFLDELAEKHGIEDPETLHIWKTNSLLLRFWVNALKNPQLTFDVRVSDNEDAILAVIAQTFIDSCVISEHKVGRDSPVNKLLYAREIPCYKQMVEKYYADIHQSSPVSYQEMNSTLAELSGNYTSAPHCLEALQELYNHIHRYYDQIISALEEDPVAQKMQLACRLQQIAALVENKVTDL", "length": 1908, "header": "tr|A0A9J7KDI1-1|A0A9J7KDI1_CRIGR Isoform 1 of Plexin-B3 OS=Cricetulus griseus OX=10029 GN=Plxnb3 PE=3 SV=1 CANONICAL=A0A9J7KDI1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 577, "start_aa": "Thr", "end_pos": 577, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr577", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 763, "start_aa": "Thr", "end_pos": 763, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr763", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 829, "start_aa": "Thr", "end_pos": 829, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr829", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 867, "start_aa": "Thr", "end_pos": 867, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr867", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDI1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDI1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDI1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDI1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752040", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752040", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "semaphorin receptor complex", "id": "GO:0002116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002116", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDI1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDI1" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDI1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDI1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "negative regulation of cell adhesion", "id": "GO:0007162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007162", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDI1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDI1" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDI1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDI1" } ], "pmid": "" }, { "name": "regulation of cell migration", "id": "GO:0030334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030334", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDI1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDI1" } ], "pmid": "" }, { "name": "regulation of cell shape", "id": "GO:0008360", "url": 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of Dynein axonemal intermediate chain 3 OS=Cricetulus griseus OX=10029 GN=Dnai3 PE=4 SV=1 CANONICAL=A0A9J7KDI2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 558, "start_aa": "Thr", "end_pos": 558, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr558", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Directly dephosphorylates CDK1 and activates its kinase activity.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDM0#function" }, { "database": "UniProtKB", "id": "ARBA00046004", "url": "https://www.uniprot.org/uniprotkb/ARBA00046004#function" } ] }, { "annotation": "Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDM0#function" }, { "database": "UniProtKB", "id": "RU368028", "url": "https://www.uniprot.org/uniprotkb/RU368028#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDM0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100769324", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDM0", "locus": {} } ], "crossref": [ { "id": "A0A9J7KDM0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7KDM0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01530", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01530", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100769324", "url": "https://www.ncbi.nlm.nih.gov/gene/100769324", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769324", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769324", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KDM0", "url": "https://www.orthodb.org/?gene=A0A9J7KDM0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10828", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10828", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10828:SF64", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10828:SF64", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00581", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00581", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035306130", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306130", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10684", "url": "https://www.rhea-db.org/rhea/10684", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KDM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KDM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDM0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPGDPLASPLSLLENGILMENEMRYLGSPTTTVPKLSKNLKLEDQEGLSEESVEFSLEDQDTKGLSLKTMVSLCGINAIQMEEEEPDQGHLIGDFSKVCVLPKVSGKHQDLKYITPDTVAALPSVKFQGLIEKFYNIDCHYPYEYLGGHILGALNLYSQKELHEFFLKKPTVPLDIQKRIIIVFLCEFSSERGPRMCRSLREKDRALNQYPALYYPELYILKGGYRDFFPEYTELCEPQSYCPMHHQDHQVELLRWRSKSKAQEGERQLLEQIALLVKKDVNPQ", "length": 284, "header": "tr|A0A9J7KDM0-1|A0A9J7KDM0_CRIGR Isoform 1 of M-phase inducer phosphatase OS=Cricetulus griseus OX=10029 GN=LOC100769324 PE=3 SV=1 CANONICAL=A0A9J7KDM0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KDM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDM0/entry#A0A9J7KDM0-1", "sequence": { "sequence": "MPGDPLASPLSLLENGILMENEMRYLGSPTTTVPKLSKNLKLEDQEGLSEESVEFSLEDQDTKGLSLKTMVSLCGINAIQMEEEEPDQGHLIGDFSKVCVLPKVSGKHQDLKYITPDTVAALPSVKFQGLIEKFYNIDCHYPYEYLGGHILGALNLYSQKELHEFFLKKPTVPLDIQKRIIIVFLCEFSSERGPRMCRSLREKDRALNQYPALYYPELYILKGGYRDFFPEYTELCEPQSYCPMHHQDHQVELLRWRSKSKAQEGERQLLEQIALLVKKDVNPQ", "length": 284, "header": "tr|A0A9J7KDM0-1|A0A9J7KDM0_CRIGR Isoform 1 of M-phase inducer phosphatase OS=Cricetulus griseus OX=10029 GN=LOC100769324 PE=3 SV=1 CANONICAL=A0A9J7KDM0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDM0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDM0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769324", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769324", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDM0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDM0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of G2/M transition of mitotic cell cycle", "id": "GO:0010971", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010971", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDM0" } ], "pmid": "" }, { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDM0" } ], "pmid": "" }, { "name": "G2/M transition of mitotic cell cycle", "id": "GO:0000086", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000086", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDM0" } ], "pmid": "" }, { "name": "positive regulation of G2/MI transition of meiotic cell cycle", "id": "GO:0110032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110032", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDM0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDM0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10684", "name": "", "equation": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3H060-1", "G3H622-1", "G3H9Q0-1", "A0A8C2LH05-1", "G3HKY7-1", "G3GWQ6-1", "G3HBF6-1", "G3GRD1-1", "G3H8H2-1", "A0A9J7FG56-1", 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"id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2LVB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVB9" } ] } ] }, { "uniprot_ac": "A0A8C2LYZ8", "gene_name": "Ptprf", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2LYZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYZ8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2LYZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYZ8" } ] } ] }, { "uniprot_ac": "A0A8C2MFV5", "gene_name": "LOC100758361", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFV5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2MFV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MFV5" } ] } ] }, { "uniprot_ac": "A0A8C2MQ28", "gene_name": "Ptprz1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MQ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ28" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2MQ28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MQ28" } ] } ] }, { "uniprot_ac": "A0A8C2MZ43", "gene_name": "Ptprg", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2MZ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ43" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2MZ43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MZ43" } ] } ] }, { "uniprot_ac": "A0A8C2N2E5", "gene_name": "Dusp15", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2N2E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N2E5" } ] } ] }, { "uniprot_ac": "A0A8C2N686", "gene_name": "Ptp4a1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2N686", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N686" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2N686", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N686" } ] } ] }, { "uniprot_ac": "A0A8C2QC02", "gene_name": "Ptpn6", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QC02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC02" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QC02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QC02" } ] } ] }, { "uniprot_ac": "A0A8C2QCP2", "gene_name": "Dusp28", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QCP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QCP2" } ] } ] }, { "uniprot_ac": "A0A8C2QH88", "gene_name": "Dusp12", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A8C2QH88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QH88" } ] } ] }, { "uniprot_ac": "A0A9J7EXY7", "gene_name": "Ptpn13", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EXY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXY7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EXY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXY7" } ] } ] }, { "uniprot_ac": "A0A9J7EY47", "gene_name": "Cdkn3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EY47", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EY47" } ] } ] }, { "uniprot_ac": "A0A9J7EZC9", "gene_name": "Ptpn18", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZC9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EZC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZC9" } ] } ] }, { "uniprot_ac": "A0A9J7EZL1", "gene_name": "LOC113830718", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7EZL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EZL1" } ] } ] }, { "uniprot_ac": "A0A9J7F2A0", "gene_name": "Ptpn12", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7F2A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2A0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7F2A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2A0" } ] } ] }, { "uniprot_ac": "A0A9J7FB56", "gene_name": "Ptpru", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FB56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FB56" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FB56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FB56" } ] } ] }, { "uniprot_ac": "A0A9J7FEN1", "gene_name": "Eya1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FEN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEN1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FEN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEN1" } ] } ] }, { "uniprot_ac": "A0A9J7FEZ5", "gene_name": "Ptpn2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FEZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEZ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FEZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FEZ5" } ] } ] }, { "uniprot_ac": "A0A9J7FG56", "gene_name": "Cdc25c", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FG56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FG56" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FG56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FG56" } ] } ] }, { "uniprot_ac": "A0A9J7FIV0", "gene_name": "LOC100763249", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FIV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FIV0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FIV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FIV0" } ] } ] }, { "uniprot_ac": "A0A9J7FKB3", "gene_name": "Pten", "activity": [ { "ec_number": "3.1.3.67", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.67", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKB3" } ] } ] }, { "uniprot_ac": "A0A9J7FMB0", "gene_name": "Dusp5", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FMB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMB0" } ] } ] }, { "uniprot_ac": "A0A9J7FWJ6", "gene_name": "Dusp7", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7FWJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWJ6" } ] } ] }, { "uniprot_ac": "A0A9J7FWX7", "gene_name": "LOC103158664", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWX7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FWX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWX7" } ] } ] }, { "uniprot_ac": "A0A9J7FYL8", "gene_name": "Ptpn11", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7FYL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYL8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7FYL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYL8" } ] } ] }, { "uniprot_ac": "A0A9J7G003", "gene_name": "Ptprs", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G003", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G003" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G003", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G003" } ] } ] }, { "uniprot_ac": "A0A9J7G168", "gene_name": "LOC100762307", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G168", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G168" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G168", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G168" } ] } ] }, { "uniprot_ac": "A0A9J7G1A0", "gene_name": "Ptpn4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G1A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1A0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G1A0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1A0" } ] } ] }, { "uniprot_ac": "A0A9J7G7K2", "gene_name": "Ptpn1", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G7K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7K2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G7K2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7K2" } ] } ] }, { "uniprot_ac": "A0A9J7G7L1", "gene_name": "Ptprj", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7G7L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7L1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7G7L1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7L1" } ] } ] }, { "uniprot_ac": "A0A9J7GBQ5", "gene_name": "LOC100764354", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GBQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ5" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GBQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBQ5" } ] } ] }, { "uniprot_ac": "A0A9J7GE78", "gene_name": "Dusp3", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "A0A9J7GE78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GE78" } ] } ] }, { "uniprot_ac": "A0A9J7GNR2", "gene_name": "Ptpn3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GNR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GNR2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GNR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GNR2" } ] } ] }, { "uniprot_ac": "A0A9J7GQC8", "gene_name": "LOC100757114", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GQC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQC8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GQC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQC8" } ] } ] }, { "uniprot_ac": "A0A9J7GQG9", "gene_name": "Ptprd", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GQG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQG9" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GQG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GQG9" } ] } ] }, { "uniprot_ac": "A0A9J7GX92", "gene_name": "Ptpre", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX92" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GX92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX92" } ] } ] }, { "uniprot_ac": "A0A9J7GZK0", "gene_name": "Ptprc", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7GZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZK0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7GZK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZK0" } ] } ] }, { "uniprot_ac": "A0A9J7H152", "gene_name": "Ptprt", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7H152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H152" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7H152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H152" } ] } ] }, { "uniprot_ac": "A0A9J7H7L7", "gene_name": "Ptprh", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7H7L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7L7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7H7L7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7L7" } ] } ] }, { "uniprot_ac": "A0A9J7HBK7", "gene_name": "Ptpn22", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7HBK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBK7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7HBK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBK7" } ] } ] }, { "uniprot_ac": "A0A9J7J766", "gene_name": "Ptpn20", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7J766", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J766" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7J766", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J766" } ] } ] }, { "uniprot_ac": "A0A9J7JC04", "gene_name": "Eya3", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JC04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JC04" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JC04", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JC04" } ] } ] }, { "uniprot_ac": "A0A9J7JC62", "gene_name": "Tns2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JC62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JC62" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JC62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JC62" } ] } ] }, { "uniprot_ac": "A0A9J7JD11", "gene_name": "Ptprm", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JD11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JD11" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JD11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JD11" } ] } ] }, { "uniprot_ac": "A0A9J7JTT7", "gene_name": "Ptpra", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JTT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTT7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JTT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTT7" } ] } ] }, { "uniprot_ac": "A0A9J7JU39", "gene_name": "Eya4", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7JU39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU39" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7JU39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU39" } ] } ] }, { "uniprot_ac": "A0A9J7KAX8", "gene_name": "Eya2", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7KAX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAX8" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7KAX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAX8" } ] } ] }, { "uniprot_ac": "A0A9J7KDA7", "gene_name": "Ptprb", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7KDA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDA7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7KDA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDA7" } ] } ] }, { "uniprot_ac": "A0A9J7KDM0", "gene_name": "LOC100769324", "activity": [ { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "A0A9J7KDM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDM0" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "A0A9J7KDM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDM0" } ] } ] }, { "uniprot_ac": "G3GRD1", "gene_name": "Dusp10", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3GRD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRD1" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3GRD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRD1" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3GRD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRD1" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3GRD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GRD1" } ] } ] }, { "uniprot_ac": "G3GWQ6", "gene_name": "Dusp29", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3GWQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWQ6" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3GWQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWQ6" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3GWQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWQ6" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3GWQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3GWQ6" } ] } ] }, { "uniprot_ac": "G3H060", "gene_name": "Dusp26", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3H060", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H060" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3H060", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H060" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3H060", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H060" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3H060", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H060" } ] } ] }, { "uniprot_ac": "G3H622", "gene_name": "Dusp4", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3H622", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H622" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3H622", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H622" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3H622", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H622" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3H622", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H622" } ] } ] }, { "uniprot_ac": "G3H8H2", "gene_name": "Dusp19", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3H8H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8H2" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3H8H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8H2" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3H8H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8H2" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3H8H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3H8H2" } ] } ] }, { "uniprot_ac": "G3H9Q0", "gene_name": "Dusp1", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": 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"G3HBF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HBF6" } ] } ] }, { "uniprot_ac": "G3HKY7", "gene_name": "Dusp6", "activity": [ { "ec_number": "3.1.3.16", "activity": "O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate.", "evidence": [ { "id": "G3HKY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HKY7" } ] }, { "ec_number": "3.1.3.48", "activity": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "G3HKY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HKY7" } ] }, { "ec_number": "3.1.3.16", "activity": "", "evidence": [ { "id": "G3HKY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HKY7" } ] }, { "ec_number": "3.1.3.48", "activity": "", "evidence": [ { "id": "G3HKY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/G3HKY7" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7KDM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDM0" }, { "id": "PS50206", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50206" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rhodanese", "eco_id": "ECO_0000259", "start_pos": 130, "end_pos": 237, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.3.48", "ec_name": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "3.1.3.48", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48" }, { "id": "3.1.3.48", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.3.48" } ] } ], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEP2/entry#names_and_taxonomy" } ] }, { "name": "F-actin-binding protein", "type": "synonym", "evidence": [ { "id": "A0A9J7KEP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEP2/entry#names_and_taxonomy" } ] }, { "name": "nexilin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035307749", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307749" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307749", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307749" } ] }, { "annotation": "Involved in regulating cell migration through association with the actin cytoskeleton. Has an essential role in the maintenance of Z line and sarcomere integrity.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDP4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDP4#function" }, { "database": "UniProtKB", "id": "ARBA00058759", "url": "https://www.uniprot.org/uniprotkb/ARBA00058759#function" }, { "database": "UniProtKB", "id": "A0A9J7KEP2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEP2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KEP2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEP2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Nexn", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEP2", "locus": {} } ], "crossref": [ { "id": "A0A9J7KEP2", "url": 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"url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757659", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KEP2", "url": "https://www.orthodb.org/?gene=A0A9J7KEP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21508", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21508", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21508:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21508:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307749", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307749", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KDP4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KDP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KEP2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KEP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEP2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLASDDEEEISAKIEKAYVPKLTGTVKGKFDEMEKHRQEEQRKRTDEERKRRLEQDLLEKRKIQRELAKRAEQIEDISNTGTESAAEEGDDSLLITVVPAKSYKTSGKIKNTEDLEKEQGKERVNHEDDKTGRYEEECPSLKEAKCLSLVMDDETEAKKESHFPGKLKLTFEELEQQRQENRKKQAEEEARRRLEEERRAFEEERQRMVNEEDENQDTRKVFKEYRPGKLKLSFEELERQRREEEKRKAEEEARRRIEEEKKAFAEARRSMVQDDDSPEIYKTVSQESLMPGKLEINFEELLRQKMEEERRRTEEERRHKLEMEKQGFEQLRQEMGEEEEENETFGLSREYEELIKLKRSGSIQAKNLKSKFEKIGQLSEKEIQKKIEEERAKRRAIDLEIKEREAENFHEEDDVDVKPAKKSESPFTHKVNMKARFEQMAKAREEEEQRRIEEQKLLRMQFEQKEIDAALQKKREDEEEEEGGIVNGSTTEDEEQTRSGAPWFKKPLRNTSVVDSEPVRFTVKVTGEPKPQVTWWFEGEMLQDGEDYQYIERGETYCLYLPETFPEDGGEYMCKAVNSKGSAASTCILTIESKD", "length": 595, "header": "tr|A0A9J7KEP2-1|A0A9J7KEP2_CRIGR Isoform 1 of Nexilin OS=Cricetulus griseus OX=10029 GN=Nexn PE=4 SV=1 CANONICAL=A0A9J7KEP2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KDP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEP2/entry#A0A9J7KDP4-1", "sequence": { "sequence": "MLASDDEEEISAKIEKAYVPKLTGTVKGKFDEMEKHRQEEQRKRTDEERKRRLEQDLLEKRKIQRELAKRAEQEGDDSLLITVVPAKSYKTSGKIKNTEDLEKEQGKERVNHEDDKTGRYEEECPSLKEAKCLSLVMDDETEAKKESHFPGKLKLTFEELEQQRQENRKKQAEEEARRRLEEERRAFEEERQRMVNEEDENQDTRKVFKEYRPGKLKLSFEELERQRREEEKRKAEEEARRRIEEEKKAFAEARRSMVQDDDSPEIYKTVSQESLMPGKLEINFEELLRQKMEEERRRTEEERRHKLEMEKQGFEQLRQEMGEEEEENETFGLSREYEELIKLKRSGSIQAKNLKSKFEKIGQLSEKEIQKKIEEERAKRRAIDLEIKEREAENFHEEDDVDVKPAKKSESPFTHKVNMKARFEQMAKAREEEEQRRIEEQKLLRMQFEQKEIDAALQKKREDEEEEEGGIVNGSTTEDEEQTRSGAPWFKKPLRNTSVVDSEPVRFTVKVTGEPKPQVTWWFEGEMLQDGEDYQYIERGETYCLYLPETFPEDGGEYMCKAVNSKGSAASTCILTIESKD", "length": 581, "header": "tr|A0A9J7KDP4-1|A0A9J7KEP2_CRIGR Computationally mapped isoform of Nexilin OS=Cricetulus griseus OX=10029 GN=Nexn PE=4 SV=1 CANONICAL=A0A9J7KEP2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KEP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEP2/entry#A0A9J7KEP2-1", "sequence": { "sequence": "MLASDDEEEISAKIEKAYVPKLTGTVKGKFDEMEKHRQEEQRKRTDEERKRRLEQDLLEKRKIQRELAKRAEQIEDISNTGTESAAEEGDDSLLITVVPAKSYKTSGKIKNTEDLEKEQGKERVNHEDDKTGRYEEECPSLKEAKCLSLVMDDETEAKKESHFPGKLKLTFEELEQQRQENRKKQAEEEARRRLEEERRAFEEERQRMVNEEDENQDTRKVFKEYRPGKLKLSFEELERQRREEEKRKAEEEARRRIEEEKKAFAEARRSMVQDDDSPEIYKTVSQESLMPGKLEINFEELLRQKMEEERRRTEEERRHKLEMEKQGFEQLRQEMGEEEEENETFGLSREYEELIKLKRSGSIQAKNLKSKFEKIGQLSEKEIQKKIEEERAKRRAIDLEIKEREAENFHEEDDVDVKPAKKSESPFTHKVNMKARFEQMAKAREEEEQRRIEEQKLLRMQFEQKEIDAALQKKREDEEEEEGGIVNGSTTEDEEQTRSGAPWFKKPLRNTSVVDSEPVRFTVKVTGEPKPQVTWWFEGEMLQDGEDYQYIERGETYCLYLPETFPEDGGEYMCKAVNSKGSAASTCILTIESKD", "length": 595, "header": "tr|A0A9J7KEP2-1|A0A9J7KEP2_CRIGR Isoform 1 of Nexilin OS=Cricetulus griseus OX=10029 GN=Nexn PE=4 SV=1 CANONICAL=A0A9J7KEP2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDW7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDW7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758376", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758376", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Set1C/COMPASS complex", "id": "GO:0048188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048188", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KDW7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KDW7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": 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This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035308249", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308249" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KE13", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE13" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rasa3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE13", "locus": {} } ], "crossref": [ { "id": "A0A9J7KE13", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7KE13", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04010", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04010", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05134", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05134", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08401", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08401", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13371", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13371", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100752063", "url": "https://www.ncbi.nlm.nih.gov/gene/100752063", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001562", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001562", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037774", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037774", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039360", "url": 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"MLFKLGPRVCLRRHITKYQGNCPEPYTRCGEGGGEAKNLPSYPGPNKMRDCYCTVNLDQEEVFRTKIVEKSLCPFYGEDFYCEIPRSFRHLSFYIFDRDVFRRDSIIGKVAIQKEDLQSYHNRDTWFQLQHVDADSEVQGKVHLELRLSEVITDTGVVCHKLAARIFECQGLPIVNGQCDPYATVTLAGPFRSEAKKTKVKKKTNNPHFDEVFYFEVTRPCSYSKKSHFDFEEEDVDKLEIRVDLWNASNLKFGDEFLGELRIPLKVLRHSSSYEAWYFLQPRDNGSKSLKPDDLGSLRLNVVYTEDHVFSSEYYSPLRDLLLKSADVEPVSASAAHILGEVCRDKQEAAIPLVRLLLHYGRVVPFISAIASAEVKRTQDPNTIFRGNSLTSKCIDETMKLAGMHYLHVTLKPTIEEICQSHKSCEIDPVKLKDGENLENNMESLRQYVDRIFTVITKSGVSCPTVMCDIFFSLREAAAKRFQDDLDVRYTAVSSFIFLRFFAPAILSPNLFQLTPHHTDPQTSRTLTLISKTIQTLGSLSKSKSASFKESYMATFYEFFNEQKYADAVKNFLDLISSSGRRDPKSIEQPILLKEGFMIKRAQGRKRFGMKNFKKRWFRLTNHEFTYQKSKGDQPLCSIPIENILAVERLEEESFRMKNMFQVIQPERALYIQANNCVEAKDWIDILTKVSQCNQKRLTVYHPSAYLNGHWLCCRASSDTAAGCTPCTGGLPANIQLDIDGDRETERIYSLFNLYMGKLEKMQEACGSKSVYDGPEQEEYSTFIIDDPQETYKTLKQVIAGVGTLEQEHAQYRRDKFKKTRYGSQEHPIGDKSFQNYIRQQSEISTHSI", "length": 849, "header": "tr|A0A9J7KE13-1|A0A9J7KE13_CRIGR Isoform 1 of Ras GTPase-activating protein 3 OS=Cricetulus griseus OX=10029 GN=Rasa3 PE=4 SV=1 CANONICAL=A0A9J7KE13-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MK06-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE13/entry#A0A8C2MK06-1", "sequence": { "sequence": "MAVEEEGLRVFQSVRIKIGEAKNLPSYPGPNKMRDCYCTVNLDQEEVFRTKIVEKSLCPFYGEDFYCEIPRSFRHLSFYIFDRDVFRRDSIIGKVAIQKEDLQSYHNRDTWFQLQHVDADSEVQGKVHLELRLSEVITDTGVVCHKLAARIFECQGLPIVNGQCDPYATVTLAGPFRSEAKKTKVKKKTNNPHFDEVFYFEVTRPCSYSKKSHFDFEEEDVDKLEIRVDLWNASNLKFGDEFLGELRIPLKVLRHSSSYEAWYFLQPRDNGSKSLKPDDLGSLRLNVVYTEDHVFSSEYYSPLRDLLLKSADVEPVSASAAHILGEVCRDKQEAAIPLVRLLLHYGRVVPFISAIASAEVKRTQDPNTIFRGNSLTSKCIDETMKLAGMHYLHVTLKPTIEEICQSHKSCEIDPVKLKDGENLENNMESLRQYVDRIFTVITKSGVSCPTVMCDIFFSLREAAAKRFQDDLDVRYTAVSSFIFLRFFAPAILSPNLFQLTPHHTDPQTSRTLTLISKTIQTLGSLSKSKSASFKESYMATFYEFFNEQKYADAVKNFLDLISSSGRRDPKSIEQPILLKEGFMIKRAQGRKRFGMKNFKKRWFRLTNHEFTYQKSKGDQPLCSIPIENILAVERLEEESFRMKNMFQVIQPERALYIQANNCVEAKDWIDILTKVSQCNQKRLTVYHPSAYLNGHWLCCRASSDTAAGCTPCTGGLPANIQLDIDGDRETERIYSLFNLYMGKLEKMQEACGSKSVYDGPEQEEYSTFIIDDPQETYKTLKQVIAGVGTLEQEHAQYRRDKFKKTRYGSQEHPIGDKSFQNYIRQQSEISTHSI", "length": 834, "header": "tr|A0A8C2MK06-1|A0A8C2MK06_CRIGR Computationally mapped isoform of Ras GTPase-activating protein 3 OS=Cricetulus griseus OX=10029 GN=Rasa3 PE=4 SV=1 CANONICAL=A0A9J7KE13-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KE13-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE13/entry#A0A9J7KE13-1", "sequence": { "sequence": "MLFKLGPRVCLRRHITKYQGNCPEPYTRCGEGGGEAKNLPSYPGPNKMRDCYCTVNLDQEEVFRTKIVEKSLCPFYGEDFYCEIPRSFRHLSFYIFDRDVFRRDSIIGKVAIQKEDLQSYHNRDTWFQLQHVDADSEVQGKVHLELRLSEVITDTGVVCHKLAARIFECQGLPIVNGQCDPYATVTLAGPFRSEAKKTKVKKKTNNPHFDEVFYFEVTRPCSYSKKSHFDFEEEDVDKLEIRVDLWNASNLKFGDEFLGELRIPLKVLRHSSSYEAWYFLQPRDNGSKSLKPDDLGSLRLNVVYTEDHVFSSEYYSPLRDLLLKSADVEPVSASAAHILGEVCRDKQEAAIPLVRLLLHYGRVVPFISAIASAEVKRTQDPNTIFRGNSLTSKCIDETMKLAGMHYLHVTLKPTIEEICQSHKSCEIDPVKLKDGENLENNMESLRQYVDRIFTVITKSGVSCPTVMCDIFFSLREAAAKRFQDDLDVRYTAVSSFIFLRFFAPAILSPNLFQLTPHHTDPQTSRTLTLISKTIQTLGSLSKSKSASFKESYMATFYEFFNEQKYADAVKNFLDLISSSGRRDPKSIEQPILLKEGFMIKRAQGRKRFGMKNFKKRWFRLTNHEFTYQKSKGDQPLCSIPIENILAVERLEEESFRMKNMFQVIQPERALYIQANNCVEAKDWIDILTKVSQCNQKRLTVYHPSAYLNGHWLCCRASSDTAAGCTPCTGGLPANIQLDIDGDRETERIYSLFNLYMGKLEKMQEACGSKSVYDGPEQEEYSTFIIDDPQETYKTLKQVIAGVGTLEQEHAQYRRDKFKKTRYGSQEHPIGDKSFQNYIRQQSEISTHSI", "length": 849, "header": "tr|A0A9J7KE13-1|A0A9J7KE13_CRIGR Isoform 1 of Ras GTPase-activating protein 3 OS=Cricetulus griseus OX=10029 GN=Rasa3 PE=4 SV=1 CANONICAL=A0A9J7KE13-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KE13", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE13" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KE13", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE13" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752063", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752063", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E7F916-1", "protein_name": "Ras GTPase-activating protein 2", "gene_name": "rasa3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAVEEEGLRVFQSVKIKIGEAKNIPPYPGPNKMRDCYCTVNLDQEEVFRTKTIEKSLCPFYGEDFYCEIPRSFRHLSFYIFDRDVFRRDSSIGKVAVKKEDLQKYHGKDHWFPLQPVCADSEVQGKVHLELRLSELITDSGGLCHKLATRVLECQDLPIVNGQCDPYAAVSLLGPSRSEAKKTKVKRKNNNPQFDEIFFFEVTKPLSFTKRQFDVEEDDVDKLALKVDLWNASNLKFGDEFLGEVRVPLKVLGQAGVHDAWYFLQPRDNGHKSVKADELGSLRLNIVYTEDHVFPTEHYNPLRDLLLQSAHVQPVSASAAHILGEVCREKQEAAVPLVRLFLHYGKIVPFLSAIAHAEISRTQDPNTIFRGNSLTSKCIDETMKLAGMHYLRVTLKPIIDEICSDHKPCEIDPVKLKESENLDTNRENLRQYVDRIFSVITSSGVSCPTVMCDIFFSLRESAASRFQVDADVRYTAVSSFIFLRFFAPAILSPNLFHLRPHHPDPCTSRTLTLISKTIQTLGSLAKSKSANFKESYMAAFYDYFNEQKYADAVKNFLDLISSSARWDQKSIETPIMLKEGFMIKRAQGRNRFGLKNFKKRWFRLTNHEFTYHKTKGEGALCSIPIENILAVERLEEESFKMKNMFQVIQPERALYIQANNCVEARDWIDILTKVSQCNRKRLSTFHPSAFLNGHWLCCKLSADTAPGCTPCTGGLPANIQLDVDGDRETERIYSLYSTYMSKLVKMQEACGSKSVYDGPEQEEYSTFVIDDPQETYKTLRLVISAVQTLEQQHTQYKRDKFRKTKYGSQEHPIGDQSFQCYIRQQSESSTYSI", "length": 833 }, "evidence": [ { "id": "A0A9J7KE13", "url": "https://omabrowser.org/oma/group/A0A9J7KE13/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P48423-1", "protein_name": "GTPase-activating protein", "gene_name": "RasGAP1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLLKKKRYMFDERDDNNINSPVAVEPSSNNNKMADTREVRIEEQLKVKIGEAKNLSSRNAANTSCSTQGTRDVYCTIALDQEEICRTPTIERTLTPFFGEEHQFKIPRRFRYLTIYLWDRDMKQDKPIGKIAIKREELHMYNHKDHWFSLRPVDQDSEVQGMVNVEVAFTEAQQTQSLSEGIDLGQHTLRHHQNLPHHSHQQRAHLNDYKENSELSNIQRASAAAASSSSAAMTLKTRAAGLFGHVHHPPSQTQHFPIINTTSTSSDQLSNWKSHGRFVGVTIKVPACVDLAKKQGTCDPFVVCTAHYSNKHQVTRRTKQRKKTVDPEFDEAMYFDLHIDADAGSTNTTGSNKSAGSLESSANKGYSIYPVGGADLVEIVVSVWHDAHGAMSDKVFLGEVRLPMLNKQEQQAVNPSAWYYLQPRSMTHSSRSLNATPRSCATPPGTRLSVDSTIGSLRLNLNYTADHVFPLATYDDLMNLLLESVDQRPITVSAVSILGELVSGKTEVAQPLVRLFTHTERIAPIIKALADHEISHLTDPTTIFRGNTLVSKMMDEAMRLSGLHYLHQTLRPVLSQIVAEKKPCEIDPSKIKDRSAVDTNLHNLQDYVERVFEAITKSADRCPKVLCQIFHDLRECAGEHFPSNREVRYSVVSGFIFLRFFAPAILGPKLFDLTTERLDAQTSRTLTLISKTIQSLGNLVSSRSSQQTCKEEFTVELYKKFCTEQHVDAVKHFLEVISTPSHASSSVHPAAAAATPLEPVLLKEGLMTKYPTSRKRFGRQFKQRHFRLTTHSLSYAKSKGKQPICDIPLQEIASVEQLKDKSFKMQNCFKIVHNDRSLIVQTTNCVEEREWFDLLHKICLMNSIRMQYFHPSAFVSGFYSCCGRSDENSPGCKKVLDKTMDYFQMDLVTALDPALDLQRIHTLIMSNMSVLESLLDPLTYHQSLSQTQHQQHNPLVPLATDLQKHSPQAFAEFKRTIEKLREKAYAIDRDHRDYKQGITRQLKYGSRQAPIGDDNYWHMMRAAGQLNQQHHQQQQHQQQQQQQQQQQLQQFQPQPVLPQMQNVRAYPYQPATSNMNAYCLHNMQYQQQRLPFHQQQQQHHQQLQQQQSQFQPLRSHQLQRHNNNLNNNNCGNGSSSSPSSTTSSVVAAPPSTTSSSQPAPPIY", "length": 1163 }, "evidence": [ { "id": "A0A9J7KE13", "url": "https://omabrowser.org/oma/group/A0A9J7KE13/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q14644-1", "protein_name": "Ras GTPase-activating protein 3", "gene_name": "RASA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVEDEGLRVFQSVKIKIGEAKNLPSYPGPSKMRDCYCTVNLDQEEVFRTKIVEKSLCPFYGEDFYCEIPRSFRHLSFYIFDRDVFRRDSIIGKVAIQKEDLQKYHNRDTWFQLQHVDADSEVQGKVHLELRLSEVITDTGVVCHKLATRIVECQGLPIVNGQCDPYATVTLAGPFRSEAKKTKVKRKTNNPQFDEVFYFEVTRPCSYSKKSHFDFEEEDVDKLEIRVDLWNASNLKFGDEFLGELRIPLKVLRQSSSYEAWYFLQPRDNGSKSLKPDDLGSLRLNVVYTEDHVFSSDYYSPLRDLLLKSADVEPVSASAAHILGEVCREKQEAAVPLVRLFLHYGRVVPFISAIASAEVKRTQDPNTIFRGNSLASKCIDETMKLAGMHYLHVTLKPAIEEICQSHKPCEIDPVKLKDGENLENNMENLRQYVDRVFHAITESGVSCPTVMCDIFFSLREAAAKRFQDDPDVRYTAVSSFIFLRFFAPAILSPNLFQLTPHHTDPQTSRTLTLISKTVQTLGSLSKSKSASFKESYMATFYEFFNEQKYADAVKNFLDLISSSGRRDPKSVEQPIVLKEGFMIKRAQGRKRFGMKNFKKRWFRLTNHEFTYHKSKGDQPLYSIPIENILAVEKLEEESFKMKNMFQVIQPERALYIQANNCVEAKDWIDILTKVSQCNQKRLTVYHPSAYLSGHWLCCRAPSDSAPGCSPCTGGLPANIQLDIDGDRETERIYSLFNLYMSKLEKMQEACGSKSVYDGPEQEEYSTFVIDDPQETYKTLKQVIAGVGALEQEHAQYKRDKFKKTKYGSQEHPIGDKSFQNYIRQQSETSTHSI", "length": 834 }, "evidence": [ { "id": "A0A9J7KE13", "url": "https://omabrowser.org/oma/group/A0A9J7KE13/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q60790-1", "protein_name": "Ras GTPase-activating protein 3", "gene_name": "Rasa3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVEEEGLRVFQSVRIKIGEAKNLPSYPGPNKMRDCYCTVNLDQEEVFRTKIVEKSLCPFYGEDFYCEIPRSFRHLSFYIFDRDVFRRDSIIGKVAIQKEDLQRYHNRDTWFQLQHVDADSEVQGKVHLELRLSEVITDTGVVCHKLAARIFECQGLPIVNGQCDPYATVTLAGPFRSEAKKTKVKKKTNNPQFDEVFYFEVTRPCSYSKKSHFDFEEEDVDKLEIRVDLWNASNLKFGDEFLGELRLPLKILRHSSSYEAWYFLQPRDNGNKSLKPDDLGSLRLNVVYTEDHVFSSEYYSPLRDLLLKSADVEPVSASAAHILGEVCRDKQEAAIPLVRLLLHYGRVVPFISAIASAEVKRTQDPNTIFRGNSLTSKCIDETMKLAGMHYLHVTLKPTIEEICQSHKSCEIDPVKLKDGENLENNMESLRQYVDRIFTVITKSGVSCPTVMCDIFFSLREAAAKRFQDDLDVRYTAVSSFIFLRFFAPAILSPNLFQLTPHHTDPQTSRTLTLISKTIQTLGSLSKSKSASFKESYMATFYEFFNEQKYADAVKNFLDLISSSGRRDPKSIEQPILLKEGFMIKRAQGRKRFGMKNFKKRWFRLTNHEFTYQKSKGDQPLCNIPIENILAVERLEEESFRMKNMFQVIQPERALYIQANNCVEAKDWIDILTKVSQCNQKRLTVFHPSAYLNGHWLCCRASSDTAAGCTPCTGGLPANIQLDIDGDRETERIYSLFNLYMGKLEKMQEACGSKSVYDGPEQEEYSTFVIDDPQETYKTLKQVIAGVGTLEQEHAQYRRDKFKKTRYGSQEHPIGDKSFQNYIRQQSEISTHSI", "length": 834 }, "evidence": [ { "id": "A0A9J7KE13", "url": "https://omabrowser.org/oma/group/A0A9J7KE13/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9QYJ2-1", "protein_name": "Ras GTPase-activating protein 3", "gene_name": "Rasa3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVEEEGLRVFQSVRIKIGEAKNLPSYPGPNKMRDCYCTVNLDQEEVFRTKIVEKSLCPFYGEDFYCEIPRSFRHLSFYIFDRDVFRRDSIIGKVAIQKEDLQRYHNRDTWFQLQHVDADSEVQGKVHLELRLSEVITDTGVVCHKLAARIFECQGLPIVNGQCDPYATVTLAGPFRSEAKKTKVKKKTNNPQFDEVFYFEVTRPCSYSKKSHFDFEEEDVDKLEIRVDLWNASNLKFGDEFLGELRIPLHVLRYASSYEAWYFLQPRDNGSKSVKPDDLGSLRLNVVYTEDHVFSSEYYSPLRDLLLKSADVEPVSASAAHILGEVCRDKQEAAIPLVRLLLHYGRVVPFISAIASAEVKRTQDPNTIFRGNSLTSKCIDETMKLAGMHYLHVTLKPTIEEICQSHKSCEIDPVKLKDGENLENNMESLRQYVDRIFSVITKSGVSCPTVMCDIFFSLREAAAKRFQDDLDVRYTAVSSFIFLRFFAPAILSPNLFQLTPHHTDPQTSRTLTLISKTIQTLGSLSKSKSASFKESYMATFYEFFNEQKYADAVKNFLDLISSSGRRDPKSIEQPILLKEGFMIKRAQGRKRFGMKNFKKRWFRLTNHEFTYQKSKGDQPLCNIPIENILAVERLEEESFRMKNMFQVIQPERALYIQANNCVEAKDWIDILTKVSQCNQKRLTVFHPSAYLNGHWLCCRASSDTAIGCTPCTGGLPANIQLDIDGDRETERIYSLFNLYMGKLEKMQEACGSKSVYDGPEQEEYSTFIIDDPQETYRTLKQVIAGVGTLEQEHAQYRRNKFKKTRYGSQEHPIGDKSFQNYIRQQSEISTHSI", "length": 834 }, "evidence": [ { "id": "A0A9J7KE13", "url": "https://omabrowser.org/oma/group/A0A9J7KE13/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of Ras protein signal transduction", "id": "GO:0046580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046580", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KE13", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE13" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KE13", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE13" } ], "pmid": "" }, { "name": "response to stress", "id": "GO:0006950", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006950", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KE13", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE13" } ], "pmid": "" }, { "name": "platelet activation", "id": "GO:0030168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030168", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KE13", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE13" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KE13", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE13" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KE13", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE13" } ], "pmid": "" }, { "name": "calcium channel regulator activity", "id": "GO:0005246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005246", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KE13", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE13" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasmic side of plasma membrane", "id": "GO:0009898", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009898", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KE13", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE13" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 247, "end_pos": 249, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7KE13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE13" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 127, "start_aa": "Pro", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7KE13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE13" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 591, "end_pos": 692, "start_aa": "Ile", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7KE13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KE13" }, { "id": "PS50018", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50018" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ras-GAP", "eco_id": "ECO_0000259", "start_pos": 345, "end_pos": 539, "start_aa": "Asp", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 247, "end_pos": 249 }, { "start_pos": 285, "end_pos": 287 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, 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pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 19% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307239", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307239" } ] }, { "annotation": "Co-chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp60, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per ring, followed by the binding of ATP and association with 2 heptameric rings of the co-chaperonin Hsp10. This leads to sequestration of the substrate protein in the inner cavity of Hsp60 where, for a certain period of time, it can fold undisturbed by other cell components. Synchronous hydrolysis of ATP in all Hsp60 subunits results in the dissociation of the chaperonin rings and the release of ADP and the folded substrate protein.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KED2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KED2#function" }, { "database": "UniProtKB", "id": "ARBA00046093", "url": "https://www.uniprot.org/uniprotkb/ARBA00046093#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KED2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KED2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113832935", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KED2", "locus": {} } ], "crossref": [ { "id": "A0A9J7KED2", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7KED2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00320", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00320", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "113832935", "url": "https://www.ncbi.nlm.nih.gov/gene/113832935", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011032", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020818", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020818", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037124", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037124", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113832935", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113832935", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KED2", "url": "https://www.orthodb.org/?gene=A0A9J7KED2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10772", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10772", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10772:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10772:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00166", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00166", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307239", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307239", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KED2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KED2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KED2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KED2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGGWEGSRISALSLQWRPECNPSCSDASQGWTSFQKFLPLFDTVLVERNAAETVTKGGIMLPEKSQGKVLQATLVAVGSGTKGKGGDIQPVSVKVGDKVLLPENGGTKVVLDDKDYFLFRDADILGKYMD", "length": 130, "header": "tr|A0A9J7KED2-1|A0A9J7KED2_CRIGR Isoform 1 of 10 kDa heat shock protein, mitochondrial OS=Cricetulus griseus OX=10029 GN=LOC113832935 PE=3 SV=1 CANONICAL=A0A9J7KED2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KED2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KED2/entry#A0A9J7KED2-1", "sequence": { "sequence": "MGGWEGSRISALSLQWRPECNPSCSDASQGWTSFQKFLPLFDTVLVERNAAETVTKGGIMLPEKSQGKVLQATLVAVGSGTKGKGGDIQPVSVKVGDKVLLPENGGTKVVLDDKDYFLFRDADILGKYMD", "length": 130, "header": "tr|A0A9J7KED2-1|A0A9J7KED2_CRIGR Isoform 1 of 10 kDa heat shock protein, mitochondrial OS=Cricetulus griseus OX=10029 GN=LOC113832935 PE=3 SV=1 CANONICAL=A0A9J7KED2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"evidence": [ { "database": "UniProtKB", "id": "A0A9J7KED2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KED2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KED5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KED5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KED5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KED5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774376", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774376", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KED5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KED5" } ], "pmid": "" }, { "name": "phenylalanine 4-monooxygenase activity", "id": "GO:0004505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004505", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KED5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KED5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "L-phenylalanine catabolic process", "id": "GO:0006559", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006559", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KED5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KED5" } ], "pmid": "" }, { "name": "phenol-containing compound biosynthetic process", "id": "GO:0046189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046189", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KED5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KED5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], 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This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307289", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307289" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KEE1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEE1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tes", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEE1", "locus": {} } ], "crossref": [ { "id": "cd09413", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09413", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09416", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09416", "database": "CDD", 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"https://www.ebi.ac.uk/interpro/entry/IPR034958", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034959", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034959", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034960", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034960", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047120", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047120", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751144", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751144", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KEE1", "url": "https://www.orthodb.org/?gene=A0A9J7KEE1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24211", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24211", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24211:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24211:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06297", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06297", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307289", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307289", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KEE1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KEE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEE1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWNLIPVTNDRMPEVFKGGSKLDLSNTTTNSKDATEMFKLWCKDGLRSEQGFGAPCLKCKENCEXFELHFWRKICRNCKCGQEEHDVLLSTEEDRKVGRLFEDTKYTTLIAKLKSDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPKEVKEMEQFVKKYKSEALGVGDVKLPLEMNAQGDKVYSPAGDRNTSTAVADQPKKTHYSCYCCRDIMKEGDPAVYAERAGYDKLWHPACFICSTCGELLVDMIYFWKNGKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDNILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQRFMPVEGMVFCSVECKKMMS", "length": 448, "header": "tr|A0A9J7KEE1-1|A0A9J7KEE1_CRIGR Isoform 1 of Testin OS=Cricetulus griseus OX=10029 GN=Tes PE=3 SV=1 CANONICAL=A0A9J7KEE1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KEE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEE1/entry#A0A9J7KEE1-1", "sequence": { "sequence": "MWNLIPVTNDRMPEVFKGGSKLDLSNTTTNSKDATEMFKLWCKDGLRSEQGFGAPCLKCKENCEXFELHFWRKICRNCKCGQEEHDVLLSTEEDRKVGRLFEDTKYTTLIAKLKSDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPKEVKEMEQFVKKYKSEALGVGDVKLPLEMNAQGDKVYSPAGDRNTSTAVADQPKKTHYSCYCCRDIMKEGDPAVYAERAGYDKLWHPACFICSTCGELLVDMIYFWKNGKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDNILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQRFMPVEGMVFCSVECKKMMS", "length": 448, "header": "tr|A0A9J7KEE1-1|A0A9J7KEE1_CRIGR Isoform 1 of Testin OS=Cricetulus griseus OX=10029 GN=Tes PE=3 SV=1 CANONICAL=A0A9J7KEE1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KEE1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEE1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KEE1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEE1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751144", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751144", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KEE1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEE1" } ], "pmid": "" }, { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KEE1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEE1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KEE1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEE1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 247, "end_pos": 249, "annotation": "n_glycosylation_sequon" }, { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7KEE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEE1" }, { "id": "PS50023", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50023" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding", "eco_id": "ECO_0000259", "start_pos": 261, "end_pos": 324, "start_aa": "Tyr", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7KEE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEE1" }, { "id": "PS51303", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51303" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PET", "eco_id": "ECO_0000259", "start_pos": 126, "end_pos": 233, "start_aa": "Met", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 137, "end_pos": 139 }, { "start_pos": 247, "end_pos": 249 }, { "start_pos": 26, "end_pos": 28 }, { "start_pos": 406, "end_pos": 408 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7KEE8-1", "uniprot_ac": "A0A9J7KEE8", "uniprot_id": "A0A9J7KEE8_CRIGR", "mass": { "chemical_mass": 113424.0, "monoisotopic_mass": 113424.0 }, "refseq": { "ac": "XP_035307328", "name": "ral guanine nucleotide dissociation stimulator-like 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307328" }, "gene_names": [ { "name": "Rgl2", "type": "recommended", "evidence": [ { "id": "A0A9J7KEE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEE8" } ] }, { "name": "Rgl2", "type": "synonym", "evidence": [ { "id": "XP_035307328", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307328" } ] } ], "protein_names": [ { "name": "Ral guanine nucleotide dissociation stimulator-like 2", "type": "recommended", "evidence": [ { "id": "A0A9J7KEE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEE8/entry#names_and_taxonomy" } ] }, { "name": "RalGDS-like factor", "type": "synonym", "evidence": [ { "id": "A0A9J7KEE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEE8/entry#names_and_taxonomy" } ] }, { "name": "Ras-associated protein RAB2L", "type": "synonym", "evidence": [ { "id": "A0A9J7KEE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEE8/entry#names_and_taxonomy" } ] }, { "name": "ral guanine nucleotide dissociation stimulator-like 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035307328", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307328" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 18% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307328", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307328" } ] }, { "annotation": "Probable guanine nucleotide exchange factor. Putative effector of Ras and/or Rap. Associates with the GTP-bound form of Rap 1A and H-Ras in vitro.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KEE8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEE8#function" }, { "database": "UniProtKB", "id": "ARBA00057664", "url": "https://www.uniprot.org/uniprotkb/ARBA00057664#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KEE8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEE8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rgl2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEE8", "locus": {} } ], "crossref": [ { "id": "A0A9J7KEE8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7KEE8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00155", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00155", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06224", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06224", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd17211", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17211", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100752656", "url": "https://www.ncbi.nlm.nih.gov/gene/100752656", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000651", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000651", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019804", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019804", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752656", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752656", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KEE8", "url": 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X2", "type": "synonym", "evidence": [ { "id": "A0A9J7KEF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEF5/entry#names_and_taxonomy" } ] }, { "name": "signal transducer CD24-like isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035307353", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307353" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 45% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307353", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307353" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KEF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEF5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100774863", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEF5", "locus": {} } ], "crossref": [ { "id": "A0A9J7KEF5", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7KEF5", "database": "AlphaFoldDB", "categories": [] }, { "id": "100774863", "url": "https://www.ncbi.nlm.nih.gov/gene/100774863", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774863", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774863", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KEF5", "url": "https://www.orthodb.org/?gene=A0A9J7KEF5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16676", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16676", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16676:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16676:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14984", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14984", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307353", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307353", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KEF5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KEF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEF5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQRTDHKCPAPTDTLTKQFLHLRLTEYCDKGDRNIVRVRGPTLPADLPALSIHRVPPHANGADVGRAMVVRLGLGLLLLALLLPTQIYCNQTSVAPFSSNQSISTAPNPTNATTRAGGSALQSTAGLLAISLSLLHFYC", "length": 139, "header": "tr|A0A9J7KEF5-1|A0A9J7KEF5_CRIGR Isoform 1 of Signal transducer CD24-like isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100774863 PE=4 SV=1 CANONICAL=A0A9J7KEF5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KEF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEF5/entry#A0A9J7KEF5-1", "sequence": { "sequence": "MQRTDHKCPAPTDTLTKQFLHLRLTEYCDKGDRNIVRVRGPTLPADLPALSIHRVPPHANGADVGRAMVVRLGLGLLLLALLLPTQIYCNQTSVAPFSSNQSISTAPNPTNATTRAGGSALQSTAGLLAISLSLLHFYC", "length": 139, "header": "tr|A0A9J7KEF5-1|A0A9J7KEF5_CRIGR Isoform 1 of Signal transducer CD24-like isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100774863 PE=4 SV=1 CANONICAL=A0A9J7KEF5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KEJ2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEJ2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"database": "UniProtKB", "id": "A0A9J7KEJ2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEJ2" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KEJ2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEJ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KEJ2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEJ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7KEK0-1", "uniprot_ac": "A0A9J7KEK0", "uniprot_id": "A0A9J7KEK0_CRIGR", "mass": { "chemical_mass": 451663.0, "monoisotopic_mass": 451663.0 }, "refseq": { "ac": "XP_035308947", "name": "extracellular matrix protein FRAS1 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308947" }, "gene_names": [ { "name": "LOC100753685", "type": "recommended", "evidence": [ { "id": "A0A9J7KEK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEK0" } ] }, { "name": "LOC100753685", "type": "synonym", "evidence": [ { "id": "XP_035308947", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308947" } ] } ], "protein_names": [ { "name": "Extracellular matrix protein FRAS1 isoform X3", "type": "synonym", "evidence": [ { "id": "A0A9J7KEK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEK0/entry#names_and_taxonomy" } ] }, { "name": "extracellular matrix protein FRAS1 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_035308947", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308947" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 2% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035308947", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308947" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KEK0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEK0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100753685", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEK0", "locus": {} } ], "crossref": [ { "id": "cd00064", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00064", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100753685", "url": "https://www.ncbi.nlm.nih.gov/gene/100753685", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003644", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003644", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006212", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006212", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038081", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038081", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051561", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051561", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753685", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753685", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KEK0", "url": "https://www.orthodb.org/?gene=A0A9J7KEK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45739", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45739", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45739:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45739:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00093", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00093", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03160", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03160", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16184", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16184", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035308947", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308947", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KEK0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KEK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEK0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 4094, "header": "tr|A0A9J7KEK0-1|A0A9J7KEK0_CRIGR Isoform 1 of Extracellular matrix protein FRAS1 isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC100753685 PE=3 SV=1 CANONICAL=A0A9J7KEK0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KEK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEK0/entry#A0A9J7KEK0-1", "sequence": { "sequence": "MSSRGVGSYRGGNEIIGTRELSLMNKETVSEKGNSYGRKEGDHSWRELMEAIVAGCDGNSIQHEAGTVVTGMVDLEDGFHPLIENMGNPLAFNTVYSGFFRETEQDATVWKPDSCQNCRCHGDMVICKPVVCKNPRCAFAKGEVLQIAPNQCCPQCALRTSGFCHHEGQIHEHGTEWTSTPCTVCSCTHGEVRCSHRPCSPLSCGPQELEFLAEGGCCPICVGAGKPCSYDGHIYQDGEEWRLSRCAKCVCRNGLIQCFTAQCQPLFCNQDEIVVRVPGKCCPQCSARSCSAAGQVYEHGEQWKEDACTLCMCDQGEVRCHKQACPPLKCEKGQSRARHHGQCCEECVSPDKSCSSSGILRYQDEMWKGSACEFCTCDQGQVTCQTGECAKVACALGEELVHLEGKCCPECISRKGYCVYEQKAEIMPSNASEIKHIPEGEKWEEGPCKVCECQQAQVTCYEPSCPPCPVATLALVVKGQCCPDCTPVHCHPDCLTCSHSPDHCDLCRDPTKLLQNGRCVHSCGLGFYRAGGLCLACQPQCSTCTNGLECSSCLPPLLMQQGQCVSACGDDFYQDRHTCAVCHKSCASCWGPTEKHCLACRAPLQVLRDGSCESTCGNGFYNKQGTCIACDQSCKSCGPSSPRCLTCTEKTVLHDGKCISECPDGYYADATGRCKVCHVSCASCSGPAASHCIACIHPQALHQGHCLPSCGQGFYPNHGVCEACHASCHTCVGPKPSQCMECKKPEAGLRVEQHSGTNVPYGECVPQCGSHFYLESTGRCEACDPSCLQCAGKSPLSCTVCKPAHVLLSGRCLSQCPESHFNLEGTCTECHPSCRQCHGPLESDCVSCHPHLTLTSGYCKTSCKEEQFLNFVGYCADCHPLCQHCVANLHDTGSICLKCQHARHLLLGDHCVADCPPGHYAERGTCKRCHSSCRSCQNGGPFSCSSCATGLLLTHIGTCSTTCFPGHYPDDNQVCQPCNMHCRSCDSQGSCTSCREPSKVLLFGECHYESCAPQYYLDISTKTCRECDWSCNACSGPLRTDCLQCMDGYVLQDGVCMEQCSVEHYRDSGFCKRCSSHCLQCQGPHECTRCEEPFLLFQAQCVQECGKGYFPDHAKHKCTACPRGCLQCSHRDGCRLCGHGFFLKSGLCMPTCVPGFSGHSSNETCTDKMYTPSLHVNGSLILGIGSMKPLDFSLLNIQHQDGRVEDLLFHVVSTPTNGQLLLSRNGKEVQLEKAGHFSWKDVNGKKVRFVHSKEKLRKGYFSLKISDQQFFSEPQLINIEAFSTQAPYVLRNEVLHISKGEQAAITTQLLDIRDDDNPQDVVVTVLDPPLHGQLLQTLPAPAAPIYQFHLDDLSRGLLLYAHDGSDSTSDVVVLQANDGHSFQNILFRVKSVPKNDGTLRLVTNSMVWVPEGGMLKITNRILQAQAPGVRAEDIIYKITHGHPQFGEVVLLMDLPADSPAGPAGPAAGPTSPAEEGQHLPDGRMATPTSTFTQQDIDDGIVWYRHSGALTQSDAFHFQVSSAADAHTHLESHMFNIAILPQAPEAPKLSLGTSLHMTAREDGLTVIQPHSLSFVNSKSPIGKIIYNITVPLHPNQGAIEHRDQPHSPIQYFSQEDINQGKIVYRPPAAASHLQEIMAYSFVGLPESVRVYFTVSDGHHTSPEMALTIHLLHSDRQPPAFQIRAPLLEVSPGGRTSLGLQLVVRDAQMVPEELFFQLQKPPQHGSLLKSTAESSGPMAAGDTFTYGEVERNALQYVHDGSSAWEDSMVISVSDGLTVTTSEVKVDVSLSENRGPRLAPGSSLSMTVASQRTAIITRSNLAYVDDSSPDPEIWIQLSSLPMYGVLLKTSGLDVEELSEGFNFTMEDINSKNIRYSAVFETEEPMVMDSFHFSVSDMDDNRVDNQVFTITITPAKSPPHIIAFADLITVDEGGRAPLSLHHFFATDDHDNLQGDAVIKLSALPKYGCIENTGTGDRFGPGATSDPEASFPIQDVLENYIYYFQSVHESIEPTHDVFSFYVSDGSSRSEIHSINVTIERKNDEPPRMTLWPLRVRLSSGVVISNSSLSLQDLDTPDNELVFVLMKKPDHGRLLQRPTASDPLENGTVLDQGSSFTYQDVLAGLVGFLPNDNGMTVDEFRFSLTDGLHVDMGRMEIYIELPTGDSPHLVINQGLQLPAGSVARITEQHLRVTDADSEDGQILYIMKEDPGAGRLQMVKPDYPEQISVRGPIRSFTQADINQGQIEYSHGPGEPLGSFAFKFDVIDREGNKLADQSFAISVLEAEFPPVIITNKGLVLDENSGKKITPAQLLATDQDSKAAELIYRITAQPQLGRLEHVASPGVQISSFTQADLTSGNVQYVHSSETRKYSDAFSFLLSDGVHEVTQTFHITIHPVDDSLPLVQNQGMRVQEGVRKTITEFELKAVDLDTEAESITFTIVQPPRHGAIERAARGQHFHLTSSFTMEDIYQNRVSYSHDGSNSLKDRFTFTVSDGTNPFFMIEEGGKEIMTAAPQQFHVDILPVDDGTPRIVTNLGLQWLEYMDGKATNLITKKELLTMDPDTEDSQLVYEVTVGPMHGYVENKLQPGRAAATFTQEDVNLGLIRYVLHEEKIQKVMDSFQFLVKDSKPNVVSNNIFHIQWSLISFKYTSYNVSEKAGSVSVTVQRTGNLNQYAIVLCRTEQGTASSSSRVSSHPGQQDYMEYAGQVQFDEREDTKSCTIVINDDDVFESVESFTVELSMPAYALLGEFTQAKVVISDTEDEPTLEFDKKTYRVNESAGFLFAPIERKGDSSSIVSAICYTVPKSAMGSSLYALESGSDFKSRGRSPESRVIFGPGITMSTCDVMIIDDSEYEEEEEFEIALADSSDNARIGRLAVAKVLISGPNDASTVSLGNTAFTISEDAGTVKIPVIRHGTDLTTFTSVWCATRPSDPASATPGVDYVPSSRKVEFGPGVTEQYCTLTILDDTQYPVIEGLETFVVFLSSAQGAELTKPFQAVIAINDTFQDVPSMQFAKDLLLVKEKEGVLHVPIIRSGDLSYESSVRCYTQSHSAQVMEDFEERRNADSSRITFLKGEKAKNCTVYIHDDSMFEPEEQFRVYLGHPLGNHWSGARVGKNSVATVTISNDEDAPTIEFEEAAYQVREPAGPDAIAVLSIKVIRRGDQNRTSKIRCSTRDGSAQSGVDYYPKSRVLKFSPGVDHIFFKVEILSNEDREWHESFSLVLGPDDPVEAVLGDVTTATVTILDQEAAGSLILPAPPIVVTLADYDHVEEVTKEGIKKAPSPGYPLVCVTPCDPHFPRYAVMKERCSEAGINQTSVQFSWEVAAPTDGNGARSPFETITDNTPFTSVNHKVLDSIYFSRRFHVRCVAKAVDKVGHVGTPLRSNVVTIGTDSAICHTPVVAGTARGFQAQSFIATLKYLDVKHKEHPNRIHISVQIPHQDGMLPLISTMPLHNLHFLLSESIYRHQHVCSNLVTARDLRGLSEAGFLDDSGFHSTALGPGYDRPFQFDPSVREPKTIQLYRHLNLKSCVWTFDAYYDMTELIDVCGGSVTADFQVRDSAQSFLTVHVPLYVSYIYVTAPRGWASLEHHTEMEFSFFYDTVLWRTGIQTDSVLSARLQIIRIYIREDGRLVIEFKTHAKFRGQFVMEHHTLPDVKSFILTPDHLGGIEFDLQLLWSAQTFDSPHQLWRATSSYNRKDYSGEYTIYLIPCTVQPTQPWVDPGEKSLACTAHAPERFLIPIAFQQTNRPVPVVYSLNTEFQLCNNEKVFLMDPNTSDMSLAEMDYKGAFSKGQILYGRVLWNPEQNLHSAYKLQLEKVYLCTGKDGYVPFFDPTGTIYNEGPQYGCIQPNKHLKHRFLLLDRSQPEVTDKYFHDVPFEAHFASELPDFHVVSSMPGVDGFTLKVDALYKVEAGHQWYLQVIYVIGPDSISRPRVQRSLTASLRRHQRDLVDPRGWLSLDDSLIYDNEGDQVKNGTNMKSLNLEMQEPIVAASLSQTGASIGSALAAIMLLLLLFLVACFITRKCQKQKKKQPPEDTLEEYPLNTKVDVAKRNADKVEKNVNRQYCTVRNVNILSDSEGSYTFKGAKVKRMNLEVRVHNNLQDGTEV", "length": 4094, "header": "tr|A0A9J7KEK0-1|A0A9J7KEK0_CRIGR Isoform 1 of Extracellular matrix protein FRAS1 isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC100753685 PE=3 SV=1 CANONICAL=A0A9J7KEK0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1470, "start_aa": "Thr", "end_pos": 1470, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1470", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2929, "start_aa": "Thr", "end_pos": 2929, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2929", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3568, "start_aa": "Thr", "end_pos": 3568, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3568", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3704, "start_aa": "Thr", "end_pos": 3704, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3704", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KEK0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEK0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KEK0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEK0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753685", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753685", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "system development", "id": "GO:0048731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048731", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KEK0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEK0" } ], "pmid": "" }, { "name": "embryonic limb morphogenesis", "id": "GO:0030326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030326", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KEK0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEK0" } ], "pmid": "" }, { "name": "cell communication", "id": "GO:0007154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007154", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KEK0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEK0" } ], "pmid": "" }, { "name": "animal organ development", "id": "GO:0048513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048513", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KEK0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEK0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KEK0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEK0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": 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This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309018", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309018" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KEM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEM0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC118239710", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEM0", "locus": {} } ], "crossref": [ { "id": "A0A9J7KEM0", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7KEM0", "database": "AlphaFoldDB", "categories": [] }, { "id": "118239710", "url": "https://www.ncbi.nlm.nih.gov/gene/118239710", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015812", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015812", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057243", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057243", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:118239710", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:118239710", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KEM0", "url": "https://www.orthodb.org/?gene=A0A9J7KEM0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10082", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10082", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10082:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10082:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07974", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07974", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309018", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309018", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KEM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KEM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEM0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTNIHALVNTAGSLHPSSFISYALVPGHGTCTCGHCVCEKGWFGKLCQHPQKCNMTEEQSKSLCESADGTLCSGKGSCHCGKCICSAEEWYISGEFCDCDDRDCDKHDGLICTGNGICNCGNCECWDGWNGNACEIWLGTEYP", "length": 143, "header": "tr|A0A9J7KEM0-1|A0A9J7KEM0_CRIGR Isoform 1 of Integrin beta-like protein 1 OS=Cricetulus griseus OX=10029 GN=LOC118239710 PE=4 SV=1 CANONICAL=A0A9J7KEM0-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KEM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEM0/entry#A0A9J7KEM0-1", "sequence": { "sequence": "MTNIHALVNTAGSLHPSSFISYALVPGHGTCTCGHCVCEKGWFGKLCQHPQKCNMTEEQSKSLCESADGTLCSGKGSCHCGKCICSAEEWYISGEFCDCDDRDCDKHDGLICTGNGICNCGNCECWDGWNGNACEIWLGTEYP", "length": 143, "header": "tr|A0A9J7KEM0-1|A0A9J7KEM0_CRIGR Isoform 1 of Integrin beta-like protein 1 OS=Cricetulus griseus OX=10029 GN=LOC118239710 PE=4 SV=1 CANONICAL=A0A9J7KEM0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KEM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEM0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KEM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEM0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:118239710", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:118239710", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "integrin binding", "id": "GO:0005178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005178", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KEM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEM0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KEM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEM0" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KEM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEM0" } ], "pmid": "" }, { "name": "integrin complex", "id": "GO:0008305", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008305", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KEM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEM0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "integrin-mediated signaling pathway", "id": "GO:0007229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007229", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KEM0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEM0" } ], "pmid": "" }, { "name": "cell migration", "id": "GO:0016477", "url": 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This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307811", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307811" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KEQ8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEQ8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100752277", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KEQ8", "locus": {} } ], "crossref": [ { "id": "A0A9J7KEQ8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7KEQ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00198", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00198", "database": "CDD", "categories": [ "Protein 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This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309412", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309412" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFX8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFX8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC118239746", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFX8", "locus": {} } ], "crossref": [ { "id": "A0A9J7KFX8", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7KFX8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04138", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04138", "database": "CDD", "categories": [ "Protein 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isoform of small monomeric GTPase OS=Cricetulus griseus OX=10029 GN=LOC118239746 PE=3 SV=1 CANONICAL=A0A9J7KFX8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KFX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFX8/entry#A0A9J7KFX8-1", "sequence": { "sequence": "MTEYQLVVVGADGVGKSALTIQLIQNLFVDEYDPTIEDSYRKQVVIDREICHLDILDTAGLEEYSAMSDQYMRTGEGFLCVFAMNNTKSFEAIHHYREQIKRVKDAEDVPMVLVGNKCDLPSRTVDTKQAQDLAGSYGIPFIETSAKTRQRVEDAFYALVREIRQYRLKKISKEEKSPGRVKIKKCIVM", "length": 189, "header": "tr|A0A9J7KFX8-1|A0A9J7KFX8_CRIGR Isoform 1 of small monomeric GTPase OS=Cricetulus griseus OX=10029 GN=LOC118239746 PE=3 SV=1 CANONICAL=A0A9J7KFX8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "cge:118239746", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:118239746", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 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"UniProtKB", "id": "A0A9J7KFX8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFX8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRJ8-1", "G3GY22-1", "G3H2D6-1", "G3HID1-1", "A0A9J7FY79-1", "G3IBI0-1", "G3HIM4-1", "G3HLW5-1", "G3I0B0-1", "G3H8L7-1", "G3IMU0-1", "G3HQ45-1", "G3HX83-1", "G3H515-1", "G3HRK4-1", "G3HWS3-1", "G3I185-1", "G3I2E9-1", "G3IHJ9-1", "G3I5Q9-1", "G3H3P1-1", "G3HGA7-1", "A0A9J7K0Q7-1", "G3I8B8-1", "A0A9J7FPY4-1", "A0A9J7JNI7-1", "A0A9J7JTM0-1", "G3HXK0-1", "G3I1T6-1", "A0A8C2M8V3-1", "G3HAT4-1", "G3HBU1-1", "A0A8C2MG78-1", "A0A9J7JFJ5-1", "A0A061I5F7-1", "A0A9J7GMX4-1", "G3H3X0-1", "A0A8C2MG41-1", 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"MTEYKLVVVGADGVGKSALTIQLIQNLFVDEYDPTIEDSYRKQVVIDREICHLDILDTAGLEEYSAMRDQYMRTGEGFLCVFAMNNTKSFEAIHHFREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLAGSYGIPFIETSAKTRQRVEDAFYALVREIRQYRLKKISKEEKTPGRVKIKKCIVM", "length": 189, "header": "tr|A0A9J7KF14-1|A0A9J7KF14_CRIGR Isoform 1 of small monomeric GTPase OS=Cricetulus griseus OX=10029 GN=LOC113838921 PE=3 SV=1 CANONICAL=A0A9J7KF14-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KF14-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KF14/entry#A0A9J7KF14-1", "sequence": { "sequence": "MTEYKLVVVGADGVGKSALTIQLIQNLFVDEYDPTIEDSYRKQVVIDREICHLDILDTAGLEEYSAMRDQYMRTGEGFLCVFAMNNTKSFEAIHHFREQIKRVKDSEDVPMVLVGNKCDLPSRTVDTKQAQDLAGSYGIPFIETSAKTRQRVEDAFYALVREIRQYRLKKISKEEKTPGRVKIKKCIVM", "length": 189, "header": "tr|A0A9J7KF14-1|A0A9J7KF14_CRIGR Isoform 1 of small monomeric GTPase OS=Cricetulus griseus OX=10029 GN=LOC113838921 PE=3 SV=1 CANONICAL=A0A9J7KF14-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], 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"https://www.uniprot.org/uniprotkb/A0A9J7KF14" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KF14", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KF14" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "G3GRJ8-1", "G3GY22-1", "G3H2D6-1", "G3HID1-1", "A0A9J7FY79-1", "G3IBI0-1", "G3HIM4-1", "G3HLW5-1", "G3I0B0-1", "G3H8L7-1", "G3IMU0-1", "G3HQ45-1", "G3HX83-1", "G3H515-1", "G3HRK4-1", "G3HWS3-1", "G3I185-1", "G3I2E9-1", "G3IHJ9-1", "G3I5Q9-1", "G3H3P1-1", "G3HGA7-1", "A0A9J7K0Q7-1", "G3I8B8-1", "A0A9J7FPY4-1", "A0A9J7JNI7-1", "A0A9J7JTM0-1", "G3HXK0-1", "G3I1T6-1", "A0A8C2M8V3-1", "G3HAT4-1", "G3HBU1-1", "A0A8C2MG78-1", "A0A9J7JFJ5-1", "A0A061I5F7-1", "A0A9J7GMX4-1", "G3H3X0-1", "A0A8C2MG41-1", "A0A8C2MJU2-1", "A0A8C2MKJ3-1", "A0A8C2QMP3-1", "A0A9J7F720-1", "A0A061IFE4-1", "A0A061HZZ7-1", "A0A8C2M6H7-1", "A0A8C2M9W6-1", "A0A9J7H2L4-1", "A0A8C2MH13-1", "A0A8C2MMV7-1", "A0A8C2MPE2-1", "A0A8C2LL65-1", "A0A3L7HXE9-1", "A0A8C2LGZ8-1", "A0A8C2LIB5-1", "A0A8C2LNU7-1", "A0A9J7JYH7-1", "A0A8C2LV21-1", "A0A9J7GDV9-1", "A0A8C2QEY0-1", "A0A9J7FVQ6-1", "A0A9J7K0X9-1", "A0A9J7J7P8-1", "A0A8C2M2X0-1", "A0A8C2MAV7-1", "A0A8C2MQL3-1", "A0A3L7HA69-1", "A0A8C2LLE7-1", "A0A061HWM0-1", "A0A061I5K5-1", "A0A061IH58-1", "A0A061INW8-1", "A0A3L7GXQ2-1", "A0A9J7GN19-1", "A0A3L7HQ44-1", "A0A3L7IA35-1", "A0A3L7IMK5-1", "A0A8C2LIE2-1", "A0A9J7GAZ9-1", "A0A9J7HCG9-1", "A0A9J7HC46-1", "A0A9J7HC79-1", "A0A9J7HCE0-1", "A0A9J7JRE1-1", "A0A9J7GJ78-1", 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"ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A061IH58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IH58" } ] } ] }, { "uniprot_ac": "A0A061INW8", "gene_name": "Nras", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A061INW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061INW8" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A061INW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061INW8" } ] } ] }, { "uniprot_ac": "A0A3L7GXQ2", "gene_name": "LOC113838564", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A3L7GXQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GXQ2" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A3L7GXQ2", "database": "UniProtKB", "url": 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Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767606", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767606", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KFF3", "url": "https://www.orthodb.org/?gene=A0A9J7KFF3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19229", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19229", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19229:SF113", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19229:SF113", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00005", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00005", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12698", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12698", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23321", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23321", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035308866", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308866", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KFF3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KFF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFF3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGHAGRQFQALFWKNWLCRLRHPVLSLAEFFWPCILFMILTVLRFQEPPRHRDSCYLQARDLPSQGVFPFVKGLLCNTGSSCRNISFESSMDHHFRLSRFQSATHDSKVSSLVFLKELQDLAEDIFETMDKAKSLQNLWLKRSETPGSSYGSSFLTMDLNKTEDVISKLESLHQQPHIWDFLHSLPRLHTINAHLEDSIDAMAHFLQAGLNSLTSLGDLDWLPLHQTIPQVSRHVLNVTISTLRFLLQHRVAVNESIYHLSLQNMVWDPQKVQSDLKSQFGFNDHQMEHILNYSAELKEIPTHSILKRMICFILSNTSEDEASSKGYQADCHPKWSAVQNYIIHAVSWLKLYAQVFDQWQQGGLLQNLLAGASHSLAALRDQFKEGSEPRKVVEALHTALLILSDSLAADGPRDSHLFAQILQHLSKLQGVVSDLSPWPVLKRLPLLDTVLRNVVTQDLRFVQGALSYLETSAKDFVPGGPDSWRLEKDVFFWGLKQLLTKKASATCLNGHLSQEVALHTGNASIWRSLWGVLCHVPSINETSVLHELLHEVKDAGHSLQEIIAGHTDGTVSEQFGNLDWQELGTQLSEVNFTCSQVFKLPGAAASTENGISPGGCEYQLVSTVMSHILEEGQKSLEQVLYWKIFLGIIRKTCELAQYVNMHESFQNSPPRKLGGLNAFSEDFPCYTQNMDWKAIIDNYFVFFNNIMKSPITSIARVLNFTKHLLVVDKKMHALENGQMSILLSLVEFLEEFLLFDPSGSLTTPEFHNLSSLSELLLNRSIPWINHLKSLERDPHDGDAQNLLEIQKLVIEKIQNIKNHWMRRESKILRFIELILLEINPELPGFWLNGTSQEGRAKFKISSTFGNFSVPEYGKILSRSFNFSQFFHSDWFKSRAVNTDFIHLSRTMIHGLYEFSFLTQEQVSIALDTIYALQNVSEIFSALSEPQKQELDDILTHINVFQDRDAALLLKTYSSLYQYFHKFLNIQNRESQINYLTHISRHILDLIKQFNIQNISKALLLLSETTEALGTIPEISYCQQLLSILNFLELQAQSLMSTEGLEPGVIHASLTGLKQLFAADEGFRVSLLQYVNQFFNGSAGTLLPSECIILENATISSVNYSGNEGASLPFLWTQLFSNLSVNGSVISEFMAIHCTLSWIQTWTEIWGNISQIFKLDLNIFTSLHVGITQLLDELENDGNISKNCQGIVPTYHTARLILNLFKNITQENGFHDWDGLQDLRDLWVSLGNELVAVQSLNLDQAEKSFVIMETSLRQLKTFSIKTNASGAFLYPLFDVFIELSKASDFVDRNVDLINNFLSSDLSEHKGKFASGITKMRETILLLRNVSQDRSLLSCADVLQSVTELTSKDNLLPVNTSKKPAHILAMLSSIFSLKNTSTSLEGCMAWADVINCLCMMFNSSSSPSHFHGTLRSFKDIENKMNSALKILTWALNKKIPICPLNESHINCVTIYLKDITEFLNIIVTTGLGKEKVHEFESLLALFNNFTKQVNMIIINLTRDFDFASQSDWKHIKDFFLRPGGMSDDITDWFQNIWQHIIALGNEMQKLFKGIFHSVLGNNSSSDTEAVFSVFSTSPKERDISRLGNSIYHLANYFAVNLTHDLQNSSKIVPNEILKAVVLGIQLTRDVFNSLMTAIHFNIPQSSDHAQVLKKMTSLMHSLKKADIELLVGQLGQIGENLMSFFKNLSRSGVDNLGVHVLVGLVKTFVDSSHSWNVNHLLRFSRLLPKEVVNTVLDVYYALPHIVGLLQRVTEKNIIESLRDIYNFTLLHGITMFNTTKEDFADVIKTLLDTVELVSDEPAVISEALMCLPRVWCLNHTTSRLEKNPEVEHCNVQGHMSSSFYHMVTSILDLLHLPHPTDSQCINENSGVEITRKVVCVTHEFADWSSILSELLEIFHVKNVLVKSLQGLWHKVLPFMSPSGNQVNGSIPELCPSSTIKQGALQVIEKLKYANFTKFLLHENILNKLGNLDKILNITEDIEISAQNNGFLNLERIFKLISAVWTLRNSTYYLLSEITNFLNVNHTDRHPDSLSSLIKNDTSTYNFEELWFDFKQNTKDPTNNSSLGQLLSDINKKIQIIALQNTTVQLPQLLEILGLSPLKMSEITEGFSFLLKHWLHEYENEDYFRLIQRLLNAMASGNSTDVTRLARDLTTYLGYLRNSSEGNLDVGILTHMLNQEQLTGFSTLQLLLESIVMNLVSYFVENSQEPALSFNGFQIMDFMTLVLNHTQSKNGGETAGSTEGFLKQLLETFFSLLNGMPENKISLLLKDLHRDFIAEMSFVPRDKILEILKLDPFLTWVNEDQLMNIFSSFTSVYYLIKNIFSLDNRELSGVLKGLTYIHPREPMVNTDAEDHLDFFTVVTQFLSQVNNSEDLSKFNQNLRSVLHLVRESSAEMANIRDILLHSPTQACHSSSSVLQHTAIAKLTDLFSVVNSSFPLRNRDALESAMRLFGAISRVGAESHVLEPALEISRTLTMLVNNTAELGGLASSVDSMVRFLSLAKKVSRKMAMMLGALSISSTKDSGKFFDTLYSFMLQSFQYHVKQITTLKKVKPFIFEKTKDLLVPFLDLAFWMIGVTPNISQDSDVFNMSSSILSYVNQSKDFSEILEEMTENLTSAKIGWRDLEHLVVVIKNRTQNFSADAINLWEEILDCLVPISNITTQMDFLKFYELSPTNCPQVLSYEGSHKAIRFLDGMLIDNSTERETFSKMVIDLTLQALWNGLKEDNWDIFNLLLTFAQHPDDLLKTIESVVEVSSGINSDYGDGLSQDLFSNLSLLQNTTRYQLAKTVLIGLSRMVPSREGRPPNNAQWIHFTHTLFHPHSNSFPNSATGQNVTSGKDGRTKEEMMALPPGSQPTSYFQKFLKALFVLIGHWQRVPQADQSVLEMCQVFLQLEKPSEAVEMLHRVEMMALHVLIIFAENPSLTKDLLCAILSCKGGGTRHLILSTMQGVTLAHHHYQEIGKIWSSPDQLDCEHLSRSLSSALEGFKRSLENASSQGCTCQPLVGTLQQHMHRLINSLKETWMTKIPVMMFLSNFTVTEDVKIKDLMKNVTKLTEDLRSSFPISDETIHSILEATISHSKVLSSVLTVALSGKCDEEILHLLLTFPESEKSWFVTRELCSLPGSQVFSLLMVMGQNLNLRNLIYKTLIPSEENGLLNSLLDVISSLSSILARAQHVLEHLPEFLHMFKITALLDMPDFQQVSQKDQARSSSLASFQSVMKLLCKDQDSFLSNSNMFVNLPRVNELLEDDKEKFNIPHDSTPFCLKLYQEILQSPNGALVWSFLKPILHGKILYTPSSPEINEVIQKANYTFYFVDKIKTLSETLLKMSSLFQGSGNGQMFNQLQDALRNKFIRNFVESQLNIDMDKLTEDLHTYGQTLDKMFNHVGAGRFQFLGGILANLSSCVVLDRFQAVEAVDTLETKAHELMQQNSFLASVIFNSSLGHRHIRSAHRKLPPHVTYTIRTNILYSMRTDMIKNPSWKFHPQSLPADGFKYNYIFVPLQDIIERAIIAVQTGQESLEPTTQAQAAPYPCHTSDLFLNNVGFFFPLIMMLTWMVSVASMVRKLVYEREIQIEEYMQMMGLHPAIHFLSWFLENMATLALSSAALAAILKMSGIFMHSDAFIVFLFLLDFGVSAVMLSYFLSVFFNQANTAALCTSLGYMISFLPYVVLLVLHNQLSFTIQTLLCLLSTTAFGQGVFFITFLEGQEEGIQWSHMYRAPEPGGMTFGWVCWMILFDSILYFLCGWYFSNLVPGTFGLGKPWYFPFTASYWKSVCGLMEKRRCSLSSGLFFFNEDFGNKGFSQQNGPGELEGGTPGVALISVTKEYEDHKVAVQELTLTFHRDQITALLGTNGAGKTTIISMLMGLYPPTSGTIIINGKNLQTDLSKVREELGVCPQQDVLLDNLTVREHLMLFASIKAPWWTKQERQQQVNKTLDEVELTLHQHKPARVLSGGMKRKLSIGIAFMGMSKTVVLDEPSSGVDPCSRRSLWDILLKYREGRTIIFTTHHLDEAEMLSDHVAVLQQGRLRCYAPPAGLKETYGQGLTLTLTKQPSILETQEPKDVAHVTSLIQVYIPQAFLKNSSGGELTYTIPKDADKTCFKGLCQALDQNLHHLHLTGYGISDTTLEEVFLMLLQDTNKKSHITPETKLEPQNERPAGSSSQHCVSPVRMSPVQSLSESVGGFQLLLGQAVALLRKRLLHTLRAWKSTTSDLLLPVLFVALAMGLFMVQPLATTYPPLKLTPGHYETAETYFFSSASHGVDLTGVLLRKFGDRDPVCVDAFLLNSSRWHRDSYSGPELQESCGCLKCPNKSAGAPYLTNCLGHTLLNLSGYDVEEYLLVPSAKPRLGGWSFGVQIPNEVEDVKTNTSKQRTLAKVWYNQKSFHSLPSYLNHLNNLILWQNLPPDAADWRQYGITLYSHPYGGALLNEDKILESIRQCGVALCIVLGFSILSASIGSSVVRDRVTGAKRLQHISGLGYRTYWLINFLYDMLFYLVSVCLCVAIIVAFQLTAFTFRENLVATALLLALFGYAMIPWMYLISRIFSSSDVAFISYISLNFIFGLCTMLMTTMPRLLAIISKAQNLQKIYNVLKWVFTIFPQFCLGQGLIELCYNQIKYDLTHNFGIDSYVSPFEMNFLGWIFVELTLQGTVLLLLRILVHGDLLRWSRVHSAPEDTVESAKDIDVEKEQRRVLEGRTGGDILVLCNLSKSYRSIFRWKTTAVHGISLGIPRGECFGLLGVNGAGKSTTFKILNGEIPPSSGYAVIRTPQGDTVDLASAGKVGILFGYCPQQDALDELLTGWEHLQYYCSLRGIPKQCIPEVAADLVKRLHLEPHVDKPVAVYSGGTRRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTITQEVQDGCAAVLTSHSMEECEALCTRLAIMVDGSFRCLGPPQHIKNRFGDGYTIKVWLHKEGRQPSVVSDCLKLHFPGIQFKGQRLNLLEYHMQKSWECLADLFKVLENNKSLLNIKHYSISQTTLEQVFVNFANEQLQSPVSC", "length": 5036, "header": "tr|A0A9J7KFF3-1|A0A9J7KFF3_CRIGR Isoform 1 of ATP-binding cassette sub-family A member 13 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100767606 PE=4 SV=1 CANONICAL=A0A9J7KFF3-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KFF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFF3/entry#A0A9J7KFF3-1", "sequence": { "sequence": "MGHAGRQFQALFWKNWLCRLRHPVLSLAEFFWPCILFMILTVLRFQEPPRHRDSCYLQARDLPSQGVFPFVKGLLCNTGSSCRNISFESSMDHHFRLSRFQSATHDSKVSSLVFLKELQDLAEDIFETMDKAKSLQNLWLKRSETPGSSYGSSFLTMDLNKTEDVISKLESLHQQPHIWDFLHSLPRLHTINAHLEDSIDAMAHFLQAGLNSLTSLGDLDWLPLHQTIPQVSRHVLNVTISTLRFLLQHRVAVNESIYHLSLQNMVWDPQKVQSDLKSQFGFNDHQMEHILNYSAELKEIPTHSILKRMICFILSNTSEDEASSKGYQADCHPKWSAVQNYIIHAVSWLKLYAQVFDQWQQGGLLQNLLAGASHSLAALRDQFKEGSEPRKVVEALHTALLILSDSLAADGPRDSHLFAQILQHLSKLQGVVSDLSPWPVLKRLPLLDTVLRNVVTQDLRFVQGALSYLETSAKDFVPGGPDSWRLEKDVFFWGLKQLLTKKASATCLNGHLSQEVALHTGNASIWRSLWGVLCHVPSINETSVLHELLHEVKDAGHSLQEIIAGHTDGTVSEQFGNLDWQELGTQLSEVNFTCSQVFKLPGAAASTENGISPGGCEYQLVSTVMSHILEEGQKSLEQVLYWKIFLGIIRKTCELAQYVNMHESFQNSPPRKLGGLNAFSEDFPCYTQNMDWKAIIDNYFVFFNNIMKSPITSIARVLNFTKHLLVVDKKMHALENGQMSILLSLVEFLEEFLLFDPSGSLTTPEFHNLSSLSELLLNRSIPWINHLKSLERDPHDGDAQNLLEIQKLVIEKIQNIKNHWMRRESKILRFIELILLEINPELPGFWLNGTSQEGRAKFKISSTFGNFSVPEYGKILSRSFNFSQFFHSDWFKSRAVNTDFIHLSRTMIHGLYEFSFLTQEQVSIALDTIYALQNVSEIFSALSEPQKQELDDILTHINVFQDRDAALLLKTYSSLYQYFHKFLNIQNRESQINYLTHISRHILDLIKQFNIQNISKALLLLSETTEALGTIPEISYCQQLLSILNFLELQAQSLMSTEGLEPGVIHASLTGLKQLFAADEGFRVSLLQYVNQFFNGSAGTLLPSECIILENATISSVNYSGNEGASLPFLWTQLFSNLSVNGSVISEFMAIHCTLSWIQTWTEIWGNISQIFKLDLNIFTSLHVGITQLLDELENDGNISKNCQGIVPTYHTARLILNLFKNITQENGFHDWDGLQDLRDLWVSLGNELVAVQSLNLDQAEKSFVIMETSLRQLKTFSIKTNASGAFLYPLFDVFIELSKASDFVDRNVDLINNFLSSDLSEHKGKFASGITKMRETILLLRNVSQDRSLLSCADVLQSVTELTSKDNLLPVNTSKKPAHILAMLSSIFSLKNTSTSLEGCMAWADVINCLCMMFNSSSSPSHFHGTLRSFKDIENKMNSALKILTWALNKKIPICPLNESHINCVTIYLKDITEFLNIIVTTGLGKEKVHEFESLLALFNNFTKQVNMIIINLTRDFDFASQSDWKHIKDFFLRPGGMSDDITDWFQNIWQHIIALGNEMQKLFKGIFHSVLGNNSSSDTEAVFSVFSTSPKERDISRLGNSIYHLANYFAVNLTHDLQNSSKIVPNEILKAVVLGIQLTRDVFNSLMTAIHFNIPQSSDHAQVLKKMTSLMHSLKKADIELLVGQLGQIGENLMSFFKNLSRSGVDNLGVHVLVGLVKTFVDSSHSWNVNHLLRFSRLLPKEVVNTVLDVYYALPHIVGLLQRVTEKNIIESLRDIYNFTLLHGITMFNTTKEDFADVIKTLLDTVELVSDEPAVISEALMCLPRVWCLNHTTSRLEKNPEVEHCNVQGHMSSSFYHMVTSILDLLHLPHPTDSQCINENSGVEITRKVVCVTHEFADWSSILSELLEIFHVKNVLVKSLQGLWHKVLPFMSPSGNQVNGSIPELCPSSTIKQGALQVIEKLKYANFTKFLLHENILNKLGNLDKILNITEDIEISAQNNGFLNLERIFKLISAVWTLRNSTYYLLSEITNFLNVNHTDRHPDSLSSLIKNDTSTYNFEELWFDFKQNTKDPTNNSSLGQLLSDINKKIQIIALQNTTVQLPQLLEILGLSPLKMSEITEGFSFLLKHWLHEYENEDYFRLIQRLLNAMASGNSTDVTRLARDLTTYLGYLRNSSEGNLDVGILTHMLNQEQLTGFSTLQLLLESIVMNLVSYFVENSQEPALSFNGFQIMDFMTLVLNHTQSKNGGETAGSTEGFLKQLLETFFSLLNGMPENKISLLLKDLHRDFIAEMSFVPRDKILEILKLDPFLTWVNEDQLMNIFSSFTSVYYLIKNIFSLDNRELSGVLKGLTYIHPREPMVNTDAEDHLDFFTVVTQFLSQVNNSEDLSKFNQNLRSVLHLVRESSAEMANIRDILLHSPTQACHSSSSVLQHTAIAKLTDLFSVVNSSFPLRNRDALESAMRLFGAISRVGAESHVLEPALEISRTLTMLVNNTAELGGLASSVDSMVRFLSLAKKVSRKMAMMLGALSISSTKDSGKFFDTLYSFMLQSFQYHVKQITTLKKVKPFIFEKTKDLLVPFLDLAFWMIGVTPNISQDSDVFNMSSSILSYVNQSKDFSEILEEMTENLTSAKIGWRDLEHLVVVIKNRTQNFSADAINLWEEILDCLVPISNITTQMDFLKFYELSPTNCPQVLSYEGSHKAIRFLDGMLIDNSTERETFSKMVIDLTLQALWNGLKEDNWDIFNLLLTFAQHPDDLLKTIESVVEVSSGINSDYGDGLSQDLFSNLSLLQNTTRYQLAKTVLIGLSRMVPSREGRPPNNAQWIHFTHTLFHPHSNSFPNSATGQNVTSGKDGRTKEEMMALPPGSQPTSYFQKFLKALFVLIGHWQRVPQADQSVLEMCQVFLQLEKPSEAVEMLHRVEMMALHVLIIFAENPSLTKDLLCAILSCKGGGTRHLILSTMQGVTLAHHHYQEIGKIWSSPDQLDCEHLSRSLSSALEGFKRSLENASSQGCTCQPLVGTLQQHMHRLINSLKETWMTKIPVMMFLSNFTVTEDVKIKDLMKNVTKLTEDLRSSFPISDETIHSILEATISHSKVLSSVLTVALSGKCDEEILHLLLTFPESEKSWFVTRELCSLPGSQVFSLLMVMGQNLNLRNLIYKTLIPSEENGLLNSLLDVISSLSSILARAQHVLEHLPEFLHMFKITALLDMPDFQQVSQKDQARSSSLASFQSVMKLLCKDQDSFLSNSNMFVNLPRVNELLEDDKEKFNIPHDSTPFCLKLYQEILQSPNGALVWSFLKPILHGKILYTPSSPEINEVIQKANYTFYFVDKIKTLSETLLKMSSLFQGSGNGQMFNQLQDALRNKFIRNFVESQLNIDMDKLTEDLHTYGQTLDKMFNHVGAGRFQFLGGILANLSSCVVLDRFQAVEAVDTLETKAHELMQQNSFLASVIFNSSLGHRHIRSAHRKLPPHVTYTIRTNILYSMRTDMIKNPSWKFHPQSLPADGFKYNYIFVPLQDIIERAIIAVQTGQESLEPTTQAQAAPYPCHTSDLFLNNVGFFFPLIMMLTWMVSVASMVRKLVYEREIQIEEYMQMMGLHPAIHFLSWFLENMATLALSSAALAAILKMSGIFMHSDAFIVFLFLLDFGVSAVMLSYFLSVFFNQANTAALCTSLGYMISFLPYVVLLVLHNQLSFTIQTLLCLLSTTAFGQGVFFITFLEGQEEGIQWSHMYRAPEPGGMTFGWVCWMILFDSILYFLCGWYFSNLVPGTFGLGKPWYFPFTASYWKSVCGLMEKRRCSLSSGLFFFNEDFGNKGFSQQNGPGELEGGTPGVALISVTKEYEDHKVAVQELTLTFHRDQITALLGTNGAGKTTIISMLMGLYPPTSGTIIINGKNLQTDLSKVREELGVCPQQDVLLDNLTVREHLMLFASIKAPWWTKQERQQQVNKTLDEVELTLHQHKPARVLSGGMKRKLSIGIAFMGMSKTVVLDEPSSGVDPCSRRSLWDILLKYREGRTIIFTTHHLDEAEMLSDHVAVLQQGRLRCYAPPAGLKETYGQGLTLTLTKQPSILETQEPKDVAHVTSLIQVYIPQAFLKNSSGGELTYTIPKDADKTCFKGLCQALDQNLHHLHLTGYGISDTTLEEVFLMLLQDTNKKSHITPETKLEPQNERPAGSSSQHCVSPVRMSPVQSLSESVGGFQLLLGQAVALLRKRLLHTLRAWKSTTSDLLLPVLFVALAMGLFMVQPLATTYPPLKLTPGHYETAETYFFSSASHGVDLTGVLLRKFGDRDPVCVDAFLLNSSRWHRDSYSGPELQESCGCLKCPNKSAGAPYLTNCLGHTLLNLSGYDVEEYLLVPSAKPRLGGWSFGVQIPNEVEDVKTNTSKQRTLAKVWYNQKSFHSLPSYLNHLNNLILWQNLPPDAADWRQYGITLYSHPYGGALLNEDKILESIRQCGVALCIVLGFSILSASIGSSVVRDRVTGAKRLQHISGLGYRTYWLINFLYDMLFYLVSVCLCVAIIVAFQLTAFTFRENLVATALLLALFGYAMIPWMYLISRIFSSSDVAFISYISLNFIFGLCTMLMTTMPRLLAIISKAQNLQKIYNVLKWVFTIFPQFCLGQGLIELCYNQIKYDLTHNFGIDSYVSPFEMNFLGWIFVELTLQGTVLLLLRILVHGDLLRWSRVHSAPEDTVESAKDIDVEKEQRRVLEGRTGGDILVLCNLSKSYRSIFRWKTTAVHGISLGIPRGECFGLLGVNGAGKSTTFKILNGEIPPSSGYAVIRTPQGDTVDLASAGKVGILFGYCPQQDALDELLTGWEHLQYYCSLRGIPKQCIPEVAADLVKRLHLEPHVDKPVAVYSGGTRRKLSTALALVGKPDILLLDEPSSGMDPCSKRYLWQTITQEVQDGCAAVLTSHSMEECEALCTRLAIMVDGSFRCLGPPQHIKNRFGDGYTIKVWLHKEGRQPSVVSDCLKLHFPGIQFKGQRLNLLEYHMQKSWECLADLFKVLENNKSLLNIKHYSISQTTLEQVFVNFANEQLQSPVSC", "length": 5036, "header": "tr|A0A9J7KFF3-1|A0A9J7KFF3_CRIGR Isoform 1 of ATP-binding cassette sub-family A member 13 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100767606 PE=4 SV=1 CANONICAL=A0A9J7KFF3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3825, "start_aa": "Thr", "end_pos": 3825, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3825", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFF3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFF3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFF3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFF3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767606", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767606", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "lipid transporter activity", "id": "GO:0005319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005319", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFF3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFF3" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFF3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFF3" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFF3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFF3" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFF3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFF3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ceramide transport", "id": "GO:0035627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035627", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFF3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFF3" } ], "pmid": "" }, { "name": "positive regulation of cholesterol transport", "id": "GO:0032376", "url": 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Involved in immune regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFG1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG1#function" }, { "database": "UniProtKB", "id": "RU369119", "url": "https://www.uniprot.org/uniprotkb/RU369119#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFG1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ido2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG1", "locus": {} } ], "crossref": [ { "id": "A0A9J7KFG1", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7KFG1", "database": "AlphaFoldDB", "categories": [] }, { "id": "100754111", "url": "https://www.ncbi.nlm.nih.gov/gene/100754111", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037217", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037217", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754111", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754111", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KFG1", "url": "https://www.orthodb.org/?gene=A0A9J7KFG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28657", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28657", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28657:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28657:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01231", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01231", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035308898", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308898", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "24536", "url": "https://www.rhea-db.org/rhea/24536", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KFG1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KFG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELQRQSLKPATWLSLGRYHISEEYGFLLRSPLKELPDEYRPWMEIANKLPHLIESHQLQAHVYKMPFLDCRFLKSHREQRLAHLVLAAITMGFIWQEGETQPQKVLPRTLAIPFVEVSRMLGLPPILVHSDLVLTNWTKRNPEGPWEISNLETIISFPGGESLRAFILVTVLVEKAAAPGIKALVQGVEAILQQSQDTLLQALQQLRLSIQDITRTLAQMHDYVDPDIFYTVIRIFLSGWKDNPAMPVGLVYEGVATEPLRYSGGSAAQSSVLQAFDEFLGIQHCMESVGFLQRMRDYMPPSHKAFLEDLHSSPSLRDYVLTSGAGCCLMAYNQCVDALVELRSYHINMVARYIISVAAKVRSGMLSHLSPHALEDRGTGGTAVMSFLKSIREKTVEAILHPCT", "length": 405, "header": "tr|A0A9J7KFG1-1|A0A9J7KFG1_CRIGR Isoform 1 of Indoleamine 2,3-dioxygenase 2 OS=Cricetulus griseus OX=10029 GN=Ido2 PE=3 SV=1 CANONICAL=A0A9J7KFG1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KFG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG1/entry#A0A9J7KFG1-1", "sequence": { "sequence": "MELQRQSLKPATWLSLGRYHISEEYGFLLRSPLKELPDEYRPWMEIANKLPHLIESHQLQAHVYKMPFLDCRFLKSHREQRLAHLVLAAITMGFIWQEGETQPQKVLPRTLAIPFVEVSRMLGLPPILVHSDLVLTNWTKRNPEGPWEISNLETIISFPGGESLRAFILVTVLVEKAAAPGIKALVQGVEAILQQSQDTLLQALQQLRLSIQDITRTLAQMHDYVDPDIFYTVIRIFLSGWKDNPAMPVGLVYEGVATEPLRYSGGSAAQSSVLQAFDEFLGIQHCMESVGFLQRMRDYMPPSHKAFLEDLHSSPSLRDYVLTSGAGCCLMAYNQCVDALVELRSYHINMVARYIISVAAKVRSGMLSHLSPHALEDRGTGGTAVMSFLKSIREKTVEAILHPCT", "length": 405, "header": "tr|A0A9J7KFG1-1|A0A9J7KFG1_CRIGR Isoform 1 of Indoleamine 2,3-dioxygenase 2 OS=Cricetulus griseus OX=10029 GN=Ido2 PE=3 SV=1 CANONICAL=A0A9J7KFG1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFG1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFG1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754111", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754111", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFG1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "L-tryptophan catabolic process to kynurenine", "id": "GO:0019441", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019441", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFG1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG1" } ], "pmid": "" }, { "name": "immune system process", "id": "GO:0002376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002376", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFG1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG1" } ], "pmid": "" }, { "name": "'de novo' NAD+ biosynthetic process from L-tryptophan", "id": "GO:0034354", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034354", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFG1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFG1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG1" } ], 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"length": 1289, "header": "tr|A0A9J7KFG2-1|A0A9J7KFG2_CRIGR Isoform 1 of LOW QUALITY PROTEIN: calcium-dependent secretion activator 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Cadps PE=4 SV=1 CANONICAL=A0A9J7KFG2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFG2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFG2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761643", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761643", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFG2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG2" } ], "pmid": "" }, { "name": "cytoplasmic vesicle membrane", "id": "GO:0030659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030659", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFG2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG2" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFG2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFG2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG2" } ], "pmid": "" }, { "name": "synaptic vesicle exocytosis", "id": "GO:0016079", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016079", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFG2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG2" } ], "pmid": "" }, { "name": "positive regulation of exocytosis", "id": "GO:0045921", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045921", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFG2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG2" } ], "pmid": "" }, { "name": "dense core granule exocytosis", "id": "GO:1990504", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990504", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFG2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFG2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG2" } ], "pmid": "" }, { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFG2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1199, 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"url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG5" } ] }, { "name": "Pkd1l1", "type": "synonym", "evidence": [ { "id": "XP_035308913", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308913" } ] } ], "protein_names": [ { "name": "Polycystin-1-like protein 1", "type": "recommended", "evidence": [ { "id": "A0A9J7KFG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG5/entry#names_and_taxonomy" } ] }, { "name": "PC1-like 1 protein", "type": "synonym", "evidence": [ { "id": "A0A9J7KFG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG5/entry#names_and_taxonomy" } ] }, { "name": "Polycystic kidney disease protein 1-like 1", "type": "synonym", "evidence": [ { "id": "A0A9J7KFG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG5/entry#names_and_taxonomy" } ] }, { "name": "polycystic kidney disease protein 1-like 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035308913", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308913" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 6% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035308913", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308913" } ] }, { "annotation": "Component of a calcium-permeant ion channel formed by PKD1L2 and PKD1L1 in primary cilia, where it controls cilium calcium concentration, without affecting cytoplasmic calcium concentration, and regulates sonic hedgehog/SHH signaling and GLI2 transcription. The PKD1L1:PKD2L1 channel complex is mechanosensitive only at high pressures and is highly temperature sensitive. Also involved in left/right axis specification downstream of nodal flow by forming a complex with PKD2 in cilia to facilitate flow detection in left/right patterning. May function as a G-protein-coupled receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFG5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG5#function" }, { "database": "UniProtKB", "id": "ARBA00054690", "url": "https://www.uniprot.org/uniprotkb/ARBA00054690#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFG5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pkd1l1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG5", "locus": {} } ], "crossref": [ { "id": "cd00146", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00146", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01752", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01752", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100754907", "url": "https://www.ncbi.nlm.nih.gov/gene/100754907", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000601", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000601", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014010", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014010", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035986", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035986", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046791", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046791", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754907", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754907", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KFG5", "url": "https://www.orthodb.org/?gene=A0A9J7KFG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46730", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46730", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46730:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46730:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00801", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00801", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01477", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01477", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20519", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20519", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035308913", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308913", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KFG5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KFG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPQLGLGRQVVFDFVAAVSEPSAVECQLGAPSAAALCSPKKEVLSSEGLLCSAEDMPKMLLLRPIPATQAENAGHFAICYFPETDAQAPPALGIRVHLASRTVLCLLVDFGDGCGAEMKLCAVTGAAAVTGYHCYRKEGVYKLRAVVHDIHGADVELGPYYVDIGRENVSVFVNSSSIHDSEALSFADSLPQQKGTVVMHRFSSVSSYNVSFISQTQVDNSQAWLGVTVGYKMQSVSIYTNGTVFAADTNITFVAVTKETLPLEFMWYLGDDPPVRTTSRSIRRRLSIPQWYHVMVKATSRIGSVVSEPHLIRIQKRIIANRLMSTASALVNANVSFECRLNFGTDVAYLWNFGDGTIDLGKSFSSHVYRREGEFTVEVLAFNNVSSAILRKQLFIVHEPCQPPPVKNMGPKQVQIWRSQPLTLRVTFEAAVLCNISQGLSYTWSIVDAGATAVTLPAAVNTHRQTIMLPSYTLECGNYTAMAKVQIKGSMVYSNYCVGVEVRPRAPVSVISEGTHIFIPRATTTPIILRGFQSYDPDNPGAALSYHWTCTAASSPRWPCFEDSTLYQMDTHAPSVSFQARWLSECCDQFLLTLTVSSNGQNSSQALIFLSTHPDPAFRFVHISWANFRDIHVNWNEELSLRAVCEDCDNVPDLTYSWDLFLVNATEKNMVEVPFCSTVGLLGSSAFGALLKLSQSGLQSNPRGPLTLHSPQRSPMPLSWTTLPNLGSTSTESTAGGHHIPVVGPLAGSGEPMEDYGSLSPAPGSSDEQALMMSTPEGSWPPSSSSPAFDDFEAYYSDIQEDVPSLGRQPGSGTNFQESGPSMDAEESASDGDNLLGPFLHTGREKPAFMIDWPKTLVSRAVFHGYTSSGIVGPAVTIKPFSLSSGEMYVLQASAASKHALLGKAQLYITINQVPRDMSCQVRPHSGLEAHTIFSVFCMSGKPDFHYEFRYQIGNTSPHTLYRGRDTQYYFLLPAGETLDNYKVIVSTEITDGQGSKVQPCTVEVTVLPRYHGNDCPDKDLYSSTLETLSSLQLVGSYTEIRNYIAMTTAILSRLYVESKNTSMCGLWSQIQDVLISSACKLPSTDQEAMMDSIHILRDLINFPNKLSWLSAMHILTYAQMFLHQGQFSRKLLVNKKLGIELILLISGVWEAAREDKRNGDYLQEEGLKIISDTLLACLSLSHQRQLHISTGQMEFWTVLHHSFQSSVQNLGFIWVHFPGDLALHSSALEESHSPCYISQLMVFMSSPYPAGQAPGQVGGVVSPRLYSCKSRRPILRGRLKTPVTVEFGEEDHRRNPTMYTLIRDEVNLHQFIGLSEKPQETLQIQIEFSKPVTRAFPIMLLVRFSKKATPTDFLVKQVYFWDEQTVQIYVPAVPVKGTNVGYLSLLDADYDRRPPNKYLAGAVNYTVNFQWIQCVFWDKTGWRSEGPCPHPGSSPEKVNCSYHRLAPFSILRRKLNATLEMSSISGFRSHPHNLIPGIFSVFLLVLYGLLMTKSRCVDCHKKKKPGCIFLEEGIPPGHQLYAVIIDTGFRSPAQFTSKVFIVLYGENGFSGTKELCCPEMSLFGRNSRHTFILSTPNQLGPLQKIRLWHDSSGPSPNWFISHVMVKELHSGQGWFFLAQCWLAVSLCDGRVQRELFCLRRGLGFWKLFYSKFTEYLEDFHIWLSLYSQPTSSSYLHAQRLAVSFCLLCVYSCLTALVTVGVHEQRSLDVGPTLESFSLGLLCTILACPAAQLLSLLFRFSKETAGHLRDAPQWPLGGVKTEAPQGMHPASDILPVTDGAWRMAASSSGMVCPSFLSVSEKSHHLPPRSQAPSSGFKGLVPQWSRVCLLWSRSVAWAICGSASLACGLGTGFLGYRFVPEQCTWWLHLLLLSVVCCTFVTQPLMICLAALVFAWKRKHDSQFFVESLHDATKDLDLELEEYSRAHILHFRSSCSPDSAEEAERVLAARQRERHLRWAQLASRAKFRVTKERLKKESQLQAALRDISMHSLMLLLLLFITYGRLCPGEYSLNQAVRKEFTRNARYSFGKPSGTDDWWDWTVSTLLNGLYPEGPAAGAWGAQPGALGGQCHLIGPSVIKQLKVSSGTACTSPRPVSELMEDALSTSTRDLDLENPNVTHGGPEACGVKKENSMHSLGRTRHEVHSALTALRANRWIDHSTRAMSVHFTLYNPPMRLFTSVTLGAEFLPMGGLVPSSLVESFSIFYSDSVPQYLLMLSELVFLVLNMTHLCFQLWGMATNGVLSYWKKPRHWLELSMIGVALAYYAASGHLTTLAKNVNDQVHKGLHQMSVDLSLMVSWNQRARWLHGSLLFLWILKCAHLLGFLNTMTSFSEVTCSSLSRAFAPALLGALLLAAHSHLYRFLLVTWTPSSSTSTDAFPRLLLQFLGRSQRDSLNNHVEPDHQAMACYRGALFLLVATLCFRMMRASLLTFFRKGKSFHRKSLVILKNVAVYSWRKFLTLLGLETTTLEETGLATDHSYYLDEFSSLLDELLVKIDGLSDNLELSILEEQWRRTVEARAVDSPLVCLSGCQATGGLWVLQVPLWTLNLGNQLIYVNTAAALSVTVKDSWKEAVSTGLIDYNCIEVGGVRTLQV", "length": 2591, "header": "tr|A0A9J7KFG5-1|A0A9J7KFG5_CRIGR Isoform 1 of Polycystin-1-like protein 1 OS=Cricetulus griseus OX=10029 GN=Pkd1l1 PE=3 SV=1 CANONICAL=A0A9J7KFG5-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KFG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG5/entry#A0A9J7KFG5-1", "sequence": { "sequence": "MRPQLGLGRQVVFDFVAAVSEPSAVECQLGAPSAAALCSPKKEVLSSEGLLCSAEDMPKMLLLRPIPATQAENAGHFAICYFPETDAQAPPALGIRVHLASRTVLCLLVDFGDGCGAEMKLCAVTGAAAVTGYHCYRKEGVYKLRAVVHDIHGADVELGPYYVDIGRENVSVFVNSSSIHDSEALSFADSLPQQKGTVVMHRFSSVSSYNVSFISQTQVDNSQAWLGVTVGYKMQSVSIYTNGTVFAADTNITFVAVTKETLPLEFMWYLGDDPPVRTTSRSIRRRLSIPQWYHVMVKATSRIGSVVSEPHLIRIQKRIIANRLMSTASALVNANVSFECRLNFGTDVAYLWNFGDGTIDLGKSFSSHVYRREGEFTVEVLAFNNVSSAILRKQLFIVHEPCQPPPVKNMGPKQVQIWRSQPLTLRVTFEAAVLCNISQGLSYTWSIVDAGATAVTLPAAVNTHRQTIMLPSYTLECGNYTAMAKVQIKGSMVYSNYCVGVEVRPRAPVSVISEGTHIFIPRATTTPIILRGFQSYDPDNPGAALSYHWTCTAASSPRWPCFEDSTLYQMDTHAPSVSFQARWLSECCDQFLLTLTVSSNGQNSSQALIFLSTHPDPAFRFVHISWANFRDIHVNWNEELSLRAVCEDCDNVPDLTYSWDLFLVNATEKNMVEVPFCSTVGLLGSSAFGALLKLSQSGLQSNPRGPLTLHSPQRSPMPLSWTTLPNLGSTSTESTAGGHHIPVVGPLAGSGEPMEDYGSLSPAPGSSDEQALMMSTPEGSWPPSSSSPAFDDFEAYYSDIQEDVPSLGRQPGSGTNFQESGPSMDAEESASDGDNLLGPFLHTGREKPAFMIDWPKTLVSRAVFHGYTSSGIVGPAVTIKPFSLSSGEMYVLQASAASKHALLGKAQLYITINQVPRDMSCQVRPHSGLEAHTIFSVFCMSGKPDFHYEFRYQIGNTSPHTLYRGRDTQYYFLLPAGETLDNYKVIVSTEITDGQGSKVQPCTVEVTVLPRYHGNDCPDKDLYSSTLETLSSLQLVGSYTEIRNYIAMTTAILSRLYVESKNTSMCGLWSQIQDVLISSACKLPSTDQEAMMDSIHILRDLINFPNKLSWLSAMHILTYAQMFLHQGQFSRKLLVNKKLGIELILLISGVWEAAREDKRNGDYLQEEGLKIISDTLLACLSLSHQRQLHISTGQMEFWTVLHHSFQSSVQNLGFIWVHFPGDLALHSSALEESHSPCYISQLMVFMSSPYPAGQAPGQVGGVVSPRLYSCKSRRPILRGRLKTPVTVEFGEEDHRRNPTMYTLIRDEVNLHQFIGLSEKPQETLQIQIEFSKPVTRAFPIMLLVRFSKKATPTDFLVKQVYFWDEQTVQIYVPAVPVKGTNVGYLSLLDADYDRRPPNKYLAGAVNYTVNFQWIQCVFWDKTGWRSEGPCPHPGSSPEKVNCSYHRLAPFSILRRKLNATLEMSSISGFRSHPHNLIPGIFSVFLLVLYGLLMTKSRCVDCHKKKKPGCIFLEEGIPPGHQLYAVIIDTGFRSPAQFTSKVFIVLYGENGFSGTKELCCPEMSLFGRNSRHTFILSTPNQLGPLQKIRLWHDSSGPSPNWFISHVMVKELHSGQGWFFLAQCWLAVSLCDGRVQRELFCLRRGLGFWKLFYSKFTEYLEDFHIWLSLYSQPTSSSYLHAQRLAVSFCLLCVYSCLTALVTVGVHEQRSLDVGPTLESFSLGLLCTILACPAAQLLSLLFRFSKETAGHLRDAPQWPLGGVKTEAPQGMHPASDILPVTDGAWRMAASSSGMVCPSFLSVSEKSHHLPPRSQAPSSGFKGLVPQWSRVCLLWSRSVAWAICGSASLACGLGTGFLGYRFVPEQCTWWLHLLLLSVVCCTFVTQPLMICLAALVFAWKRKHDSQFFVESLHDATKDLDLELEEYSRAHILHFRSSCSPDSAEEAERVLAARQRERHLRWAQLASRAKFRVTKERLKKESQLQAALRDISMHSLMLLLLLFITYGRLCPGEYSLNQAVRKEFTRNARYSFGKPSGTDDWWDWTVSTLLNGLYPEGPAAGAWGAQPGALGGQCHLIGPSVIKQLKVSSGTACTSPRPVSELMEDALSTSTRDLDLENPNVTHGGPEACGVKKENSMHSLGRTRHEVHSALTALRANRWIDHSTRAMSVHFTLYNPPMRLFTSVTLGAEFLPMGGLVPSSLVESFSIFYSDSVPQYLLMLSELVFLVLNMTHLCFQLWGMATNGVLSYWKKPRHWLELSMIGVALAYYAASGHLTTLAKNVNDQVHKGLHQMSVDLSLMVSWNQRARWLHGSLLFLWILKCAHLLGFLNTMTSFSEVTCSSLSRAFAPALLGALLLAAHSHLYRFLLVTWTPSSSTSTDAFPRLLLQFLGRSQRDSLNNHVEPDHQAMACYRGALFLLVATLCFRMMRASLLTFFRKGKSFHRKSLVILKNVAVYSWRKFLTLLGLETTTLEETGLATDHSYYLDEFSSLLDELLVKIDGLSDNLELSILEEQWRRTVEARAVDSPLVCLSGCQATGGLWVLQVPLWTLNLGNQLIYVNTAAALSVTVKDSWKEAVSTGLIDYNCIEVGGVRTLQV", "length": 2591, "header": "tr|A0A9J7KFG5-1|A0A9J7KFG5_CRIGR Isoform 1 of Polycystin-1-like protein 1 OS=Cricetulus griseus OX=10029 GN=Pkd1l1 PE=3 SV=1 CANONICAL=A0A9J7KFG5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFG5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFG5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754907", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754907", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium channel activity", "id": "GO:0005262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005262", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFG5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "ciliary membrane", "id": "GO:0060170", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060170", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFG5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1062, "end_pos": 1064, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1406, "end_pos": 1408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1441, "end_pos": 1443, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1458, "end_pos": 1460, "annotation": "n_glycosylation_sequon" }, { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 175, "end_pos": 177, "annotation": "n_glycosylation_sequon" }, { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2115, "end_pos": 2117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2224, "end_pos": 2226, "annotation": "n_glycosylation_sequon" }, { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 251, "end_pos": 253, "annotation": "n_glycosylation_sequon" }, { "start_pos": 335, "end_pos": 337, "annotation": "n_glycosylation_sequon" }, { "start_pos": 385, "end_pos": 387, "annotation": "n_glycosylation_sequon" }, { "start_pos": 436, "end_pos": 438, "annotation": "n_glycosylation_sequon" }, { "start_pos": 479, "end_pos": 481, "annotation": "n_glycosylation_sequon" }, { "start_pos": 603, "end_pos": 605, "annotation": "n_glycosylation_sequon" }, { "start_pos": 665, "end_pos": 667, "annotation": "n_glycosylation_sequon" }, { "start_pos": 956, "end_pos": 958, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7KFG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG5" }, { "id": "PS50221", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50221" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GAIN-B", "eco_id": "ECO_0000259", "start_pos": 1312, "end_pos": 1460, "start_aa": "Gln", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7KFG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG5" }, { "id": "PS50093", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50093" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PKD", "eco_id": "ECO_0000259", "start_pos": 345, "end_pos": 389, "start_aa": "Gly", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7KFG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG5" }, { "id": "PS50095", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50095" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PLAT", "eco_id": "ECO_0000259", "start_pos": 1521, "end_pos": 1638, "start_aa": "Gln", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7KFG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFG5" }, { "id": "PS51111", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51111" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "REJ", "eco_id": "ECO_0000259", "start_pos": 402, "end_pos": 1299, "start_aa": "Cys", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1062, "end_pos": 1064 }, { "start_pos": 1406, "end_pos": 1408 }, { "start_pos": 1441, "end_pos": 1443 }, { "start_pos": 1458, "end_pos": 1460 }, { "start_pos": 169, "end_pos": 171 }, { "start_pos": 175, "end_pos": 177 }, { "start_pos": 210, "end_pos": 212 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"A0A9J7KFJ1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KFJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSNNDPVAIPMIERNPNDLPGMDTSDPKTLTGEAVLSFHNISYRETVQSGFPFRKKTWVIERLSNISGIMKPGLNAIMGPQDGSRSLLLDVLAARKDPRGLSGDILINGKPRPANFQCTSGYVPQNDMVMRTVTVRENVEFSAALRIPTYVTRHEKRNRISEVLELLHLDEESNVKPRSKELRKRTSIAMELVAEHPILFLDDPTTDLDLKTATDVIKVLRTMSMRGRTIIFSINQPPYSIFKYFDSLTLVASGKVMFHGPAQEALEYFTSADYKYDSHNNPADFFLDIINGGFSSILDTEEDGHEADKYKELSERQHQVTETLSNMYTQSSLYSEMKTELDSLLEEQMAGRTPTLEEITCVTPFWHQLWWIICRSFKNFQGFPRVTAIQTIIIVTMAVAVGTTSRILRNDCTEGQTRANLLFLLTIFQVITSISAGELFVIDTDRFLHEHTSGYYSMSSYFLGKLLAELVPRRLLPSITFTVIVFFIAGIITDAKGFFTMLFTIMMLAYSTSSLPLSIGAGENATAVPTVLVTIYFAFMLFFSGLEIYSGSSLPGLSFIQYFNIPHYGFTALLHNEFLGQNFCPEHKTAEVSSCRNYVICTGEEFLMILGIDLSPWGFWQNHVALACIMIILLSITYVQLLAQREVEVLKSGWRKFQQLFKEM", "length": 665, "header": "tr|A0A9J7KFJ1-1|A0A9J7KFJ1_CRIGR Isoform 1 of ATP-binding cassette sub-family G member 3 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100774582 PE=3 SV=1 CANONICAL=A0A9J7KFJ1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KFJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFJ1/entry#A0A9J7KFJ1-1", "sequence": { "sequence": "MSSNNDPVAIPMIERNPNDLPGMDTSDPKTLTGEAVLSFHNISYRETVQSGFPFRKKTWVIERLSNISGIMKPGLNAIMGPQDGSRSLLLDVLAARKDPRGLSGDILINGKPRPANFQCTSGYVPQNDMVMRTVTVRENVEFSAALRIPTYVTRHEKRNRISEVLELLHLDEESNVKPRSKELRKRTSIAMELVAEHPILFLDDPTTDLDLKTATDVIKVLRTMSMRGRTIIFSINQPPYSIFKYFDSLTLVASGKVMFHGPAQEALEYFTSADYKYDSHNNPADFFLDIINGGFSSILDTEEDGHEADKYKELSERQHQVTETLSNMYTQSSLYSEMKTELDSLLEEQMAGRTPTLEEITCVTPFWHQLWWIICRSFKNFQGFPRVTAIQTIIIVTMAVAVGTTSRILRNDCTEGQTRANLLFLLTIFQVITSISAGELFVIDTDRFLHEHTSGYYSMSSYFLGKLLAELVPRRLLPSITFTVIVFFIAGIITDAKGFFTMLFTIMMLAYSTSSLPLSIGAGENATAVPTVLVTIYFAFMLFFSGLEIYSGSSLPGLSFIQYFNIPHYGFTALLHNEFLGQNFCPEHKTAEVSSCRNYVICTGEEFLMILGIDLSPWGFWQNHVALACIMIILLSITYVQLLAQREVEVLKSGWRKFQQLFKEM", "length": 665, "header": "tr|A0A9J7KFJ1-1|A0A9J7KFJ1_CRIGR Isoform 1 of ATP-binding cassette sub-family G member 3 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100774582 PE=3 SV=1 CANONICAL=A0A9J7KFJ1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFJ1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFJ1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFJ1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFJ1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774582", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774582", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFJ1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFJ1" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFJ1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFJ1" } ], "pmid": "" }, { "name": "efflux transmembrane transporter activity", "id": "GO:0015562", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015562", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFJ1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFJ1" } ], "pmid": "" }, { "name": "riboflavin transmembrane transporter activity", "id": "GO:0032217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032217", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFJ1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFJ1" } ], "pmid": "" }, { "name": "ABC-type transporter activity", "id": "GO:0140359", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140359", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFJ1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFJ1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFJ1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFJ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 525, "end_pos": 527, "annotation": "n_glycosylation_sequon" }, { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7KFJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFJ1" }, { "id": "PS50893", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50893" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ABC transporter", "eco_id": "ECO_0000259", "start_pos": 37, "end_pos": 279, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 41, "end_pos": 43 }, { "start_pos": 525, "end_pos": 527 }, { "start_pos": 66, "end_pos": 68 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7KFJ2-1", "uniprot_ac": "A0A9J7KFJ2", "uniprot_id": "A0A9J7KFJ2_CRIGR", "mass": { "chemical_mass": 25218.0, "monoisotopic_mass": 25218.0 }, "refseq": { "ac": "XP_035308922", "name": "LOW QUALITY PROTEIN: prohibitin-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308922" }, "gene_names": [ { "name": "LOC100766723", "type": "recommended", "evidence": [ { "id": "A0A9J7KFJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFJ2" } ] }, { "name": "LOC100766723", "type": "synonym", "evidence": [ { "id": "XP_035308922", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308922" } ] } ], "protein_names": [ { "name": "Prohibitin", "type": "recommended", "evidence": [ { "id": "A0A9J7KFJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFJ2/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: prohibitin-like", "type": "synonym", "evidence": [ { "id": "XP_035308922", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308922" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 14% of CDS bases frameshifts :: corrected 1 indel internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035308922", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308922" } ] }, { "annotation": "In the nucleus, acts as a transcription coregulator, enhances promoter binding by TP53, a transcription factor it activates, but reduces the promoter binding by E2F1, a transcription factor it represses. Interacts with STAT3 to affect IL17 secretion in T-helper Th17 cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFJ2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFJ2#function" }, { "database": "UniProtKB", "id": "ARBA00045600", "url": "https://www.uniprot.org/uniprotkb/ARBA00045600#function" } ] }, { "annotation": "In the plasma membrane, cooperates with CD86 to mediate CD86-signaling in B lymphocytes that regulates the level of IgG1 produced through the activation of distal signaling intermediates. Upon CD40 engagement, required to activate NF-kappa-B signaling pathway via phospholipase C and protein kinase C activation.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFJ2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFJ2#function" }, { "database": "UniProtKB", "id": "ARBA00046138", "url": "https://www.uniprot.org/uniprotkb/ARBA00046138#function" } ] }, { "annotation": "Protein with pleiotropic attributes mediated in a cell-compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regulator of transcription factors in the nucleus. Plays a role in adipose tissue and glucose homeostasis in a sex-specific manner. Contributes to pulmonary vascular remodeling by accelerating proliferation of pulmonary arterial smooth muscle cells.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFJ2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFJ2#function" }, { "database": "UniProtKB", "id": "ARBA00046022", "url": "https://www.uniprot.org/uniprotkb/ARBA00046022#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFJ2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFJ2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100766723", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFJ2", "locus": {} } ], "crossref": [ { "id": "cd03401", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03401", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100766723", "url": "https://www.ncbi.nlm.nih.gov/gene/100766723", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000163", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000163", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001107", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001107", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036013", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036013", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766723", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766723", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KFJ2", "url": "https://www.orthodb.org/?gene=A0A9J7KFJ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23222", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23222", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23222:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23222:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01145", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01145", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035308922", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308922", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KFJ2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KFJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSSKPFHLRSGIYEEEEAKRLKEQERVDDTKGAGSKDLENVNITLHILFWPVTSQLLRIYTSIGEDDDEQVLLSITTEILKLLVARFDAGELITQQELVSRQVSDDLTETAVTFGFILDEVSLKXLTFGKEFTEAVEAKQVAQQKSERARFVVEKAEQQEKAAIISVEGDSKAAELIVNSLATAGGSLIELHKLEAAWDIAYQLSVPSRNITYLPAGQSVLLQLPQ", "length": 227, "header": "tr|A0A9J7KFJ2-1|A0A9J7KFJ2_CRIGR Isoform 1 of Prohibitin OS=Cricetulus griseus OX=10029 GN=LOC100766723 PE=3 SV=1 CANONICAL=A0A9J7KFJ2-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KFJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFJ2/entry#A0A9J7KFJ2-1", "sequence": { "sequence": "MSSSKPFHLRSGIYEEEEAKRLKEQERVDDTKGAGSKDLENVNITLHILFWPVTSQLLRIYTSIGEDDDEQVLLSITTEILKLLVARFDAGELITQQELVSRQVSDDLTETAVTFGFILDEVSLKXLTFGKEFTEAVEAKQVAQQKSERARFVVEKAEQQEKAAIISVEGDSKAAELIVNSLATAGGSLIELHKLEAAWDIAYQLSVPSRNITYLPAGQSVLLQLPQ", "length": 227, "header": "tr|A0A9J7KFJ2-1|A0A9J7KFJ2_CRIGR Isoform 1 of Prohibitin OS=Cricetulus griseus OX=10029 GN=LOC100766723 PE=3 SV=1 CANONICAL=A0A9J7KFJ2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFJ2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFJ2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFJ2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFJ2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766723", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766723", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA biosynthetic process", "id": "GO:0071897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071897", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFJ2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFJ2" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFJ2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFJ2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFJ2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFJ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7KFJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFJ2" }, { "id": "PF01145", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01145" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Band 7", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 160, "start_aa": "Thr", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 211, "end_pos": 213 }, { "start_pos": 43, "end_pos": 45 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7KFK4-1", "uniprot_ac": "A0A9J7KFK4", "uniprot_id": "A0A9J7KFK4_CRIGR", "mass": { "chemical_mass": 125406.0, "monoisotopic_mass": 125406.0 }, "refseq": { "ac": "XP_035301762", "name": "LOW QUALITY PROTEIN: potassium channel subfamily U member 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301762" }, "gene_names": [ { "name": "Kcnu1", "type": "recommended", "evidence": [ { "id": "A0A9J7KFK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFK4" } ] }, { "name": "Kcnu1", "type": "synonym", "evidence": [ { "id": "XP_035301762", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301762" } ] } ], "protein_names": [ { "name": "Potassium channel subfamily U member 1", "type": "recommended", "evidence": [ { "id": "A0A9J7KFK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFK4/entry#names_and_taxonomy" } ] }, { "name": "BK channel", "type": "synonym", "evidence": [ { "id": "A0A9J7KFK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFK4/entry#names_and_taxonomy" } ] }, { "name": "Calcium-activated potassium channel subunit alpha-3", "type": "synonym", "evidence": [ { "id": "A0A9J7KFK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFK4/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: potassium channel subfamily U member 1", "type": "synonym", "evidence": [ { "id": "XP_035301762", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301762" } ] }, { "name": "Pore-forming subunit of the sperm-specific alkalization activated K(+) current", "type": "synonym", "evidence": [ { "id": "A0A9J7KFK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFK4/entry#names_and_taxonomy" } ] }, { "name": "Slowpoke homolog 3", "type": "synonym", "evidence": [ { "id": "A0A9J7KFK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFK4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613685.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035301762", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301762" } ] }, { "annotation": "Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K(+). Represents the primary spermatozoan K(+) current. The channel underlies a pH-triggered membrane hyperpolarization during the process of sperm capacitation, as sperm encounter the alkaline environment near the ovum in the female reproductive tract, thereby playing an essential for male fertility.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFK4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFK4#function" }, { "database": "UniProtKB", "id": "ARBA00058651", "url": "https://www.uniprot.org/uniprotkb/ARBA00058651#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFK4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFK4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Kcnu1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFK4", "locus": {} } ], "crossref": [ { "id": "100752893", "url": "https://www.ncbi.nlm.nih.gov/gene/100752893", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003148", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003148", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003929", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003929", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048735", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048735", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752893", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752893", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KFK4", "url": "https://www.orthodb.org/?gene=A0A9J7KFK4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10027", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10027", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10027:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10027:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03493", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03493", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21014", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21014", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22614", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22614", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035301762", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301762", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KFK4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KFK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFK4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFEAVLRELTEKELEEKFCTIEIQAAFILSSFVTFFGGLIILFIFRLILRVSKRFQTIKCTGIVLELFTSGRLELNPLRRLHAYRLFRNRIEMLLSAQTFVGQMLVILVFVLSIGSLVIYFINSTDPIGTCISYEDKTINVDLGFNAFFSFYFGLRFWAADDKIKFWLEMNSIVDIFTIPPTFISYYLKSNWLGLRFLRALRLLELPKILHILQVIKSSNSVKLSKLLSIVLSTWFTAAGFLHLVENSGDPWLSGRNSQHMSYFESIYLVTATMSTVGFGDVVAKTSLGRTFIVFFTLGSLILFANYIPEMVELLNNKKKYTKPYEAVKGKKFIVVCGNITVDSVTAFLRNFLRHKSGVINTEVVFLGEAPPSLELETLLKCYLSCTTFVCGSALKFEDLKRVAVESAEACLILANPLCSDLHAEDNSNIMRVLSIKNYNSQVRVIIQILQSHNKVFLSKIPTWNWSAGDNIICFAELKLGFMAQGCAVPGLCTFLTTLFIEQNQKVFPKHPWQKYFLNSLKNKIVTQHLSDDFVGMTFPEVSRLCFVKMHLMLIAIQHKSLFHNCCSLLLNPSAHVKLNKDTLGFFIAESSKVVKRAFFYCSTCHYDVHSPELIEQCVCKNRSQEQLTAPDIVVMKSSSKTTSSSENQDLISGERESSLTIAILKNRNTISDTVNDSEQLDSSGLFHWCKSMPLDKVNLKRTDKPKHEFQNHIVACVFGDAHSALVGLRNFVMPLRASNYTRRELKDIVFIGALEYLQREWRFLRNFPQIYIMPGSALYTGDLHAVNIERCSMCAILASPSKPLSSQILVDTETIMATLNIQSLRVSYPTQTTSVPDTKTAFTFDKYEGSSYERIPILTELKNPSNIHFIEQLGGLDGTVKGTSLHLSTSFSTGAVFSGNFLDSLLATAFYNCHVLELLHMLVTGGISAQMEQCLAKEKYYGIHEGCATVVSGRARCKLGLLSLDQTILSDIEPRETFGQLFCGSLDNYGILCVGLYRMMDEEEHNPEHRREVCXFEKFVITRPANECHLLPSDLVFCAIPFNTTCYKTENVSSTQILDCITNETSVAPEKHPSTQHLSKVSAGVEKTSLHSNSRVYPLEPFAASDFNQGR", 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"url": "https://www.uniprot.org/uniprotkb/A0A9J7KFX6/entry#names_and_taxonomy" } ] }, { "name": "ATPase subunit c", "type": "synonym", "evidence": [ { "id": "A0A9J7KFX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFX6/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: ATP synthase F(0) complex subunit C2, mitochondrial-like", "type": "synonym", "evidence": [ { "id": "XP_035293085", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293085" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615778.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035293085", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293085" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFX6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFX6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113831166", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFX6", "locus": {} } ], "crossref": [ { "id": "cd18182", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18182", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "113831166", "url": "https://www.ncbi.nlm.nih.gov/gene/113831166", "database": "GeneID", "categories": [ 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7KFY1-1", "uniprot_ac": "A0A9J7KFY1", "uniprot_id": "A0A9J7KFY1_CRIGR", "mass": { "chemical_mass": 95066.0, "monoisotopic_mass": 95066.0 }, "refseq": { "ac": "XP_035309615", "name": "LOW QUALITY PROTEIN: pescadillo homolog isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309615" }, "gene_names": [ { "name": "LOC103163467", "type": "recommended", "evidence": [ { "id": "A0A9J7KFY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFY1" } ] }, { "name": "LOC103163467", 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bases internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276855.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309615", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309615" } ] }, { "annotation": "Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFY1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFY1#function" }, { "database": "UniProtKB", "id": "ARBA00055102", "url": "https://www.uniprot.org/uniprotkb/ARBA00055102#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFY1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFY1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], 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"Enzyme and Pathway" ] }, { "id": "A0A9J7KFY1", "url": "https://www.orthodb.org/?gene=A0A9J7KFY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12221", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12221", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12221:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12221:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06732", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06732", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16589", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16589", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309615", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309615", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KFY1", "url": 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"MCFLFSTFPRTGKCHVQTIQLCRRLIVEFMHYVIAARALRKVFLSIKGIYYQAEVLGQPIVWIAPYAFSHDHPTDVDYRVMATFTEFYTTLLGFVNFRLYQSLNLHYPPKLEVQAQAETKISEDTYALDSESSMEKLAALSASLARVVVPTIEEAEADEFPTDGEVTAQEEDRRKELEAQEKQKKLFEGLKFFLNREVPREALAFIIRSFGGDVSWDKSLCIGATYDITDSCITHQIVDRPGQQTPIIGRYYVQPQWVFDCVNARLLLPVAEYFPGVQLPPHLSPFVSEKEGDYIPPEKLKLLALQRGEDPGDLKEEEDEDEDEDDEDDDNEGDGDGDVVGENEDEEEVDADSEKEEEAHLSVLEQQRLEGKKPQVVAGTVKLEDKQRLAQEEESEAKRLAIMMMKKREKYLYQKIMFGKRRKIREVSSGMWLSSRQTLLQTRPHCQGAHPTDVDYRVMATFTEFYTTLLGFVNFRLYQSLNLHYPPKLEGQAQAETXISEDTYALDSESSLEKLAALSASLAQVVVPTIEEAEANEFPTDGEVTAQEEDRRKELEAQEKQKKLFEGLKFFLNREVPHEALAFIIRSFGGDVSWDKSLCIGATYDITDSCITHQIVDRPGQQTHIIGRYYVQPQWVFDCVNARLLLPVAEYFPGVQLPPHLSPFVSEKEGDYIPPEKLKLLALQRGEDPGDFKEEEDEDEDEDDEDDDKEGDGDGDVVGENEDEEEVDADSEKEEEAHLSVLEQQRLEGKKPKVVAGTVKLEDKQRLAQEEESEAKRLAIMMMKKREKYLYQKIMFGKRRKIREASKLAEKRKAHDDAGRSEKKAKRTRPV", "length": 831, "header": "tr|A0A9J7KFY1-1|A0A9J7KFY1_CRIGR Isoform 1 of LOW QUALITY PROTEIN: pescadillo homolog isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC103163467 PE=4 SV=1 CANONICAL=A0A9J7KFY1-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KFY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFY1/entry#A0A9J7KFY1-1", "sequence": { "sequence": "MCFLFSTFPRTGKCHVQTIQLCRRLIVEFMHYVIAARALRKVFLSIKGIYYQAEVLGQPIVWIAPYAFSHDHPTDVDYRVMATFTEFYTTLLGFVNFRLYQSLNLHYPPKLEVQAQAETKISEDTYALDSESSMEKLAALSASLARVVVPTIEEAEADEFPTDGEVTAQEEDRRKELEAQEKQKKLFEGLKFFLNREVPREALAFIIRSFGGDVSWDKSLCIGATYDITDSCITHQIVDRPGQQTPIIGRYYVQPQWVFDCVNARLLLPVAEYFPGVQLPPHLSPFVSEKEGDYIPPEKLKLLALQRGEDPGDLKEEEDEDEDEDDEDDDNEGDGDGDVVGENEDEEEVDADSEKEEEAHLSVLEQQRLEGKKPQVVAGTVKLEDKQRLAQEEESEAKRLAIMMMKKREKYLYQKIMFGKRRKIREVSSGMWLSSRQTLLQTRPHCQGAHPTDVDYRVMATFTEFYTTLLGFVNFRLYQSLNLHYPPKLEGQAQAETXISEDTYALDSESSLEKLAALSASLAQVVVPTIEEAEANEFPTDGEVTAQEEDRRKELEAQEKQKKLFEGLKFFLNREVPHEALAFIIRSFGGDVSWDKSLCIGATYDITDSCITHQIVDRPGQQTHIIGRYYVQPQWVFDCVNARLLLPVAEYFPGVQLPPHLSPFVSEKEGDYIPPEKLKLLALQRGEDPGDFKEEEDEDEDEDDEDDDKEGDGDGDVVGENEDEEEVDADSEKEEEAHLSVLEQQRLEGKKPKVVAGTVKLEDKQRLAQEEESEAKRLAIMMMKKREKYLYQKIMFGKRRKIREASKLAEKRKAHDDAGRSEKKAKRTRPV", "length": 831, "header": "tr|A0A9J7KFY1-1|A0A9J7KFY1_CRIGR Isoform 1 of LOW QUALITY PROTEIN: pescadillo homolog isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC103163467 PE=4 SV=1 CANONICAL=A0A9J7KFY1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "cge:103163467", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103163467", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFY1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFY1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)", "id": "GO:0000463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000463", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFY1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFY1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "PeBoW complex", "id": "GO:0070545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070545", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFY1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFY1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7KFY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFY1" }, { "id": "PS50172", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50172" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BRCT", "eco_id": "ECO_0000259", "start_pos": 182, "end_pos": 275, "start_aa": "Lys", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7KFY9-1", "uniprot_ac": "A0A9J7KFY9", "uniprot_id": "A0A9J7KFY9_CRIGR", "mass": { "chemical_mass": 31936.0, "monoisotopic_mass": 31936.0 }, "refseq": { "ac": "XP_035309647", "name": "LOW QUALITY PROTEIN: ribosomal RNA-processing protein 7 homolog A-like isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309647" }, "gene_names": [ { "name": "LOC100771360", "type": "recommended", "evidence": [ { "id": "A0A9J7KFY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFY9" } ] }, { "name": "LOC100771360", "type": "synonym", "evidence": [ { "id": "XP_035309647", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309647" } ] } ], "protein_names": [ { "name": "Ribosomal RNA-processing protein 7 homolog A", "type": "recommended", "evidence": [ { "id": "A0A9J7KFY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFY9/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: ribosomal RNA-processing protein 7 homolog A-like isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035309647", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309647" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276919.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309647", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309647" } ] }, { "annotation": "Nucleolar protein that is involved in ribosomal RNA (rRNA) processing. Also plays a role in primary cilia resorption, and cell cycle progression in neurogenesis and neocortex development. Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFY9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFY9#function" }, { "database": "UniProtKB", "id": "ARBA00054533", "url": "https://www.uniprot.org/uniprotkb/ARBA00054533#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFY9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFY9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100771360", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFY9", "locus": {} } ], "crossref": [ { "id": "A0A9J7KFY9", "url": "https://alphafold.ebi.ac.uk/entry/A0A9J7KFY9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12294", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12294", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12951", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12951", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100771360", "url": "https://www.ncbi.nlm.nih.gov/gene/100771360", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024326", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024326", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034890", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034890", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040446", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040446", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040447", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040447", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771360", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771360", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KFY9", "url": "https://www.orthodb.org/?gene=A0A9J7KFY9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13191", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13191", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13191:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13191:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12923", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12923", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17799", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17799", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309647", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309647", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KFY9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KFY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFY9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVARKRKAGACGHEGSTPSPPSYSAIPVKFTKQQQASHYLYVIQHRVRGDTQSTWPPNKTLFVLNVPPYCTEECLSRLLSSCGTIKTVDLKEKPDHAESAKEAKPEFFHPKLIPGIQVAYVVFQKPSGVSATLNLKGPLLVSTENHSVRSGIHKWISEYEESVLDPEALRVEVDTFMEAYDKKIAEEETKAKEEEGVPDEEGWVKVTRRGHRPVLPQTEAASLCVLKREKSKRARKELLNFYAGQHRETTMEHLAQLCKKFKEDKQRIELMRAQYKFRPY", "length": 280, "header": "tr|A0A9J7KFY9-1|A0A9J7KFY9_CRIGR Isoform 1 of Ribosomal RNA-processing protein 7 homolog A OS=Cricetulus griseus OX=10029 GN=LOC100771360 PE=3 SV=1 CANONICAL=A0A9J7KFY9-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KFY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFY9/entry#A0A9J7KFY9-1", "sequence": { "sequence": "MVARKRKAGACGHEGSTPSPPSYSAIPVKFTKQQQASHYLYVIQHRVRGDTQSTWPPNKTLFVLNVPPYCTEECLSRLLSSCGTIKTVDLKEKPDHAESAKEAKPEFFHPKLIPGIQVAYVVFQKPSGVSATLNLKGPLLVSTENHSVRSGIHKWISEYEESVLDPEALRVEVDTFMEAYDKKIAEEETKAKEEEGVPDEEGWVKVTRRGHRPVLPQTEAASLCVLKREKSKRARKELLNFYAGQHRETTMEHLAQLCKKFKEDKQRIELMRAQYKFRPY", "length": 280, "header": "tr|A0A9J7KFY9-1|A0A9J7KFY9_CRIGR Isoform 1 of Ribosomal RNA-processing protein 7 homolog A OS=Cricetulus griseus OX=10029 GN=LOC100771360 PE=3 SV=1 CANONICAL=A0A9J7KFY9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "cge:100771360", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771360", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFY9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFY9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFY9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFY9" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFY9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFY9" } ], "pmid": "" }, { "name": "CURI complex", "id": "GO:0032545", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032545", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFY9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFY9" } ], "pmid": "" }, { "name": "UTP-C complex", "id": "GO:0034456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034456", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFY9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFY9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFY9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFY9" } ], "pmid": "" }, { "name": "ribosomal small subunit assembly", "id": "GO:0000028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000028", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFY9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFY9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 58, "end_pos": 60, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7KFY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFY9" }, { "id": "PF12923", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12923" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ribosomal RNA-processing protein 7 C-terminal", "eco_id": "ECO_0000259", "start_pos": 161, "end_pos": 280, "start_aa": "Glu", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A9J7KFY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFY9" }, { "id": "PF17799", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17799" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rrp7 RRM-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 87, "start_aa": "Tyr", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 145, "end_pos": 147 }, { "start_pos": 58, "end_pos": 60 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7KFZ8-1", "uniprot_ac": "A0A9J7KFZ8", "uniprot_id": "A0A9J7KFZ8_CRIGR", "mass": { "chemical_mass": 73358.0, "monoisotopic_mass": 73358.0 }, "refseq": { "ac": "XP_035309681", "name": "LOW QUALITY PROTEIN: forkhead box protein P4-like isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309681" }, "gene_names": [ { "name": "LOC100763161", "type": "recommended", "evidence": [ { "id": "A0A9J7KFZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFZ8" } ] }, { "name": "LOC100763161", "type": "synonym", "evidence": [ { "id": "XP_035309681", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309681" } ] } ], "protein_names": [ { "name": "LOW QUALITY PROTEIN: forkhead box protein P4-like isoform X2", "type": "synonym", "evidence": [ { "id": "XP_035309681", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309681" }, { "id": "A0A9J7KFZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFZ8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276974.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309681", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309681" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFZ8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFZ8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100763161", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFZ8", "locus": {} } ], "crossref": [ { "id": "100763161", "url": "https://www.ncbi.nlm.nih.gov/gene/100763161", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032354", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032354", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050998", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050998", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763161", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763161", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7HF21", "url": "https://www.orthodb.org/?gene=A0A9J7HF21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7KFZ8", "url": "https://www.orthodb.org/?gene=A0A9J7KFZ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45796", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45796", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45796:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45796:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00250", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00250", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16159", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16159", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309681", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309681", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7HF21", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HF21-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HF21-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KFZ8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KFZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMEESGSETIMSAPTGQKVGVGSLSGQGDGGSGSWTTGMAAVAGRDSSGRDTTRGADSDGEMSSMELLQFQQQQALQVPRQFLLQQASNLNSPGNKDSKQSASAVQVPMSEAMMSQHMLTPQQMQQNLSPPQLQALLQQQQALMPQQLQEYYKQQQQQLHLQILTQQQAGKQQPREALGNTQLAFQQQLLQMQQLQQQHLLNLQRQGLVDLQPSQASWPLQALPQAAACPTDLPQLWKGQGAPGQPAEDSFRQEGLDLASTAATATWFASAPKVSPPLCHHPLPNRQPTVLTPRRDSSSHEETPSSHPLYGQGECNWPGGETLCEDLGQFIKHLNTEHALDDQSTAQFQEQMQVVQQLEIQLTKENEGFQAMKAHVHMGPSEPKPFCQPVTVSSDPFPDGLVHPPAPAAAPVTSLQPPGLGSTSLRSGGPACRRSSHEFGSPIYSELPKYHDYFKNVAVRPPFTYASLICQAILESPDRQLTLKEICNWITRMFAFFRGKTDNWKKVVSQNLRLHECFVKVETVKGAVWTVEEQKYQKRRSSRMTESDDLGPQFWPLNTSYQAALAESNFPFLNSPDMLNPGSASSLLPLSQDDMGAPGEPLPCRGSSSPPRLSPPQXSHQVQVKEEPAEAEEDRQPWPPLGAPNPSTVGPREDRDLEEDLPGEDMS", "length": 667, "header": "tr|A0A9J7KFZ8-1|A0A9J7KFZ8_CRIGR Isoform 1 of LOW QUALITY PROTEIN: forkhead box protein P4-like isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100763161 PE=4 SV=1 CANONICAL=A0A9J7KFZ8-1" }, "isoforms": [ { "isoform_ac": "A0A9J7HF21-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFZ8/entry#A0A9J7HF21-1", "sequence": { "sequence": "RQFLLQQASNLNSPGNKDSIQLASALQVPMSEAMMSQHMLTPQQMQQNLSPPQLQALLQHQQALMPQQLQEYYKQQQQQLHLQILTQQQAGKQQPRESLGSTQLAFQQQLLQMQQLQQQHLLNLQRQGLVHLQPSQASWPLQALPQAAACPTDLPELWKGKGAPGQPAEDSIRQEGLDLASTAATATWFASAPKVSPPLSHHPLPNRQPTVLTPRRDSSSHEETPSSHPLYGHGECNWPGGETLCEDLGQFIKHLNTEHALDDQSTAQCQEQMQVVQQLEIQLTKESERFQAMKAHVHMGPSEPKPFCQPVTVSSDPFPDGLVHAPTSAAAPVTPLQPRGLGSTSLHSGGPARRRSSHEFGSPIYSELPKYHDYFKNVAVRPPFTYASLIRQAILESPDRQLTLKEICNWITRMFAFFXGKTDNWKKVVSQNLRMHECFVKVETVKGAVWTVEEQKYQKRRSSRMTGSDDLGPQFWPLNTSYQAALAESNFPFLNSPDKLNPGSASSLLPLSQDDMGAPGEPLPCKGSSSPPRLSPPQXSHEVQVKEEPAEAEEDRQPWPLLGAPNPSTVGPREDRDLEEDLPGEDMS", "length": 588, "header": "tr|A0A9J7HF21-1|A0A9J7HF21_CRIGR Computationally mapped isoform of LOW QUALITY PROTEIN: forkhead box protein P4-like isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC100763161 PE=4 SV=1 CANONICAL=A0A9J7KFZ8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KFZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFZ8/entry#A0A9J7KFZ8-1", "sequence": { "sequence": "MMEESGSETIMSAPTGQKVGVGSLSGQGDGGSGSWTTGMAAVAGRDSSGRDTTRGADSDGEMSSMELLQFQQQQALQVPRQFLLQQASNLNSPGNKDSKQSASAVQVPMSEAMMSQHMLTPQQMQQNLSPPQLQALLQQQQALMPQQLQEYYKQQQQQLHLQILTQQQAGKQQPREALGNTQLAFQQQLLQMQQLQQQHLLNLQRQGLVDLQPSQASWPLQALPQAAACPTDLPQLWKGQGAPGQPAEDSFRQEGLDLASTAATATWFASAPKVSPPLCHHPLPNRQPTVLTPRRDSSSHEETPSSHPLYGQGECNWPGGETLCEDLGQFIKHLNTEHALDDQSTAQFQEQMQVVQQLEIQLTKENEGFQAMKAHVHMGPSEPKPFCQPVTVSSDPFPDGLVHPPAPAAAPVTSLQPPGLGSTSLRSGGPACRRSSHEFGSPIYSELPKYHDYFKNVAVRPPFTYASLICQAILESPDRQLTLKEICNWITRMFAFFRGKTDNWKKVVSQNLRLHECFVKVETVKGAVWTVEEQKYQKRRSSRMTESDDLGPQFWPLNTSYQAALAESNFPFLNSPDMLNPGSASSLLPLSQDDMGAPGEPLPCRGSSSPPRLSPPQXSHQVQVKEEPAEAEEDRQPWPPLGAPNPSTVGPREDRDLEEDLPGEDMS", "length": 667, "header": "tr|A0A9J7KFZ8-1|A0A9J7KFZ8_CRIGR Isoform 1 of LOW QUALITY PROTEIN: forkhead box protein P4-like isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100763161 PE=4 SV=1 CANONICAL=A0A9J7KFZ8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "cge:100763161", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763161", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFZ8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFZ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFZ8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFZ8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFZ8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFZ8" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFZ8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFZ8" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KFZ8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFZ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 558, "end_pos": 560, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A9J7KFZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFZ8" }, { "id": "PS50039", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50039" }, { "id": "PRU00089", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fork-head", "eco_id": "ECO_0000259", "start_pos": 460, "end_pos": 546, "start_aa": "Arg", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 127, "end_pos": 129 }, { "start_pos": 558, "end_pos": 560 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A9J7KG19-1", "uniprot_ac": "A0A9J7KG19", "uniprot_id": "A0A9J7KG19_CRIGR", "mass": { "chemical_mass": 54072.0, "monoisotopic_mass": 54072.0 }, "refseq": { "ac": "XP_035309552", "name": "LOW QUALITY PROTEIN: polypyrimidine tract-binding protein 1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309552" }, "gene_names": [ { "name": "LOC113838279", "type": "recommended", "evidence": [ { "id": "A0A9J7KG19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KG19" } ] }, { "name": "LOC113838279", "type": "synonym", "evidence": [ { "id": "XP_035309552", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309552" } ] } ], "protein_names": [ { "name": "Polypyrimidine tract-binding protein 1", "type": "recommended", "evidence": [ { "id": "A0A9J7KG19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KG19/entry#names_and_taxonomy" } ] }, { "name": "Heterogeneous nuclear ribonucleoprotein I", "type": "synonym", "evidence": [ { "id": "A0A9J7KG19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KG19/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: polypyrimidine tract-binding protein 1-like", "type": "synonym", "evidence": [ { "id": "XP_035309552", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309552" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276808.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309552", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309552" } ] }, { "annotation": "Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10. Binds to polypyrimidine-rich controlling element (PCE) of CFTR and promotes exon skipping of CFTR exon 9, thereby antagonizing TIA1 and its role in exon inclusion of CFTR exon 9. Plays a role in the splicing of pyruvate kinase PKM by binding repressively to a polypyrimidine tract flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KG19", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KG19#function" }, { "database": "UniProtKB", "id": "ARBA00055436", "url": "https://www.uniprot.org/uniprotkb/ARBA00055436#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KG19", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KG19" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113838279", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KG19", "locus": {} } ], "crossref": [ { "id": "cd12777", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12777", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "113838279", "url": "https://www.ncbi.nlm.nih.gov/gene/113838279", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021790", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021790", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055204", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055204", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113838279", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113838279", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KG19", "url": "https://www.orthodb.org/?gene=A0A9J7KG19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15592", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15592", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11835", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11835", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13893", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13893", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22976", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22976", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309552", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309552", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A9J7KG19", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KG19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KG19-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KG19-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSSTSAANGNDSKKFKGDNRSTGVPSRVIHVRSLPSDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAANTMVNYYTSVAPVLRGQPIYLQFSNHKELKTDSSPNHARAQAALQAVNSVQSGNGLAASAAAVDVGMAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNRFQALLQYADPVSAQHAMLSLDGQNIYKAWCTLCIDFSKLTSLYVKYNNDKSRDYTRPDLPSGDSQPSLDQTMAAAFGLSVPNVHGALAPLAIPSAASAAAAGRIAIPGLAGAGNSVLLVSNLNPERVTPQSLFILFGVYGDVLWVKILFNNKENALVQMADGSQAQRAMRHLNAHKLHGKSLHIILSKHQSVQLPREGQEDQGLTKEYGSSPLYRFKKPGSKNFQNIFPPSPTLHFSNIPPSVSEDDLKNIFSSKGGVVKGFKFFQKDRKMALIXMGSVEEAVQALIELHNHDLGENQHLRVSFSKSTI", "length": 498, "header": "tr|A0A9J7KG19-1|A0A9J7KG19_CRIGR Isoform 1 of Polypyrimidine tract-binding protein 1 OS=Cricetulus griseus OX=10029 GN=LOC113838279 PE=4 SV=1 CANONICAL=A0A9J7KG19-1" }, "isoforms": [ { "isoform_ac": "A0A9J7KG19-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KG19/entry#A0A9J7KG19-1", "sequence": { "sequence": "MSSSTSAANGNDSKKFKGDNRSTGVPSRVIHVRSLPSDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAANTMVNYYTSVAPVLRGQPIYLQFSNHKELKTDSSPNHARAQAALQAVNSVQSGNGLAASAAAVDVGMAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNRFQALLQYADPVSAQHAMLSLDGQNIYKAWCTLCIDFSKLTSLYVKYNNDKSRDYTRPDLPSGDSQPSLDQTMAAAFGLSVPNVHGALAPLAIPSAASAAAAGRIAIPGLAGAGNSVLLVSNLNPERVTPQSLFILFGVYGDVLWVKILFNNKENALVQMADGSQAQRAMRHLNAHKLHGKSLHIILSKHQSVQLPREGQEDQGLTKEYGSSPLYRFKKPGSKNFQNIFPPSPTLHFSNIPPSVSEDDLKNIFSSKGGVVKGFKFFQKDRKMALIXMGSVEEAVQALIELHNHDLGENQHLRVSFSKSTI", "length": 498, "header": "tr|A0A9J7KG19-1|A0A9J7KG19_CRIGR Isoform 1 of Polypyrimidine tract-binding protein 1 OS=Cricetulus griseus OX=10029 GN=LOC113838279 PE=4 SV=1 CANONICAL=A0A9J7KG19-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "cge:113838279", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113838279", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { 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This record is derived from a genomic sequence (NW_003615086.1) annotated using gene prediction method: Gnomon. 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Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056737", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056737", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764135", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764135", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061HUW2", "url": "https://www.orthodb.org/?gene=A0A061HUW2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412:SF74", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412:SF74", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24981", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24981", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027288640", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288640", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061HUW2", "url": "https://www.uniprot.org/uniprotkb/A0A061HUW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061HUW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HUW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I0U8", "url": "https://www.uniprot.org/uniprotkb/A0A061I0U8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I0U8-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I0U8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GP93", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GP93-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GP93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H535", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H535", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H535-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H535-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVSGKKEFDVKQILRLRWRWFSHPSQGSPNTGSCLQQEGYEHRGTPVQGRLKNHSRDRNGLKKGNSPVHHNILTPVPGPAPTHQRVLQNWQQQNVIVHLQANEDTSKAVPEENLLKEAREKRSGDLEMMGDDNIEDSRARIYAEEPEEMNITSEDHFHSRNHADYTLSKMQNYLKEKKLCDVLLIAGHLKIPAHRLVLSAVSDYFAAMFTNDVLEARQEEVRMEGVDPNALNSLVQYAYTGMLQLREDTIENLLAAACLLQLTQVIDVCCNFLIKQLHPSNCLGILSFGDAQGCVELQNVAHKYTMEHFIEVVKNQEFLLLPANEIAKLLCSDDINVPNEETIFHALMHWVGHDAQNRQRDLAKLLSYIRLPLLSPQLLADLENSSMFTDDLECQKLLMEAMKYHLLPERRSMLQSPRTKPRKSTVGALYAVGGMDAAKGTTTIEKYDLRTNNWIHIGTMSGRRLQFGVAVVDNKLYVVGGRDGLKTLNTVECFNPVTKTWLVMPPMSTHRHGLGVATLEGPMYAVGGHDGWSYLNTVERWDPDGRQWNYVASMSTPRSTVGVVALNNKLYAIGGRDGSSCLKSMEYFDPHTNKWSLCAPMSKRRGGVGVATHNGYLYVVGGHDAPAPNHCSRLSDCVERYDPKSDSWSTVAPLSVPRDAVAVCPLGDKLYVVGGYDGHTYLNTVESYDAQKDEWNEEVPVNIGRAGACVVVVKLH", "length": 717, "header": "tr|A0A061HUW2-1|A0A061HUW2_CRIGR Isoform 1 of Kelch-like protein 4 isoform X2 OS=Cricetulus griseus OX=10029 GN=Klhl4 PE=4 SV=1 CANONICAL=A0A061HUW2-1" }, "isoforms": [ { "isoform_ac": "A0A061HUW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HUW2/entry#A0A061HUW2-1", "sequence": { "sequence": "MSVSGKKEFDVKQILRLRWRWFSHPSQGSPNTGSCLQQEGYEHRGTPVQGRLKNHSRDRNGLKKGNSPVHHNILTPVPGPAPTHQRVLQNWQQQNVIVHLQANEDTSKAVPEENLLKEAREKRSGDLEMMGDDNIEDSRARIYAEEPEEMNITSEDHFHSRNHADYTLSKMQNYLKEKKLCDVLLIAGHLKIPAHRLVLSAVSDYFAAMFTNDVLEARQEEVRMEGVDPNALNSLVQYAYTGMLQLREDTIENLLAAACLLQLTQVIDVCCNFLIKQLHPSNCLGILSFGDAQGCVELQNVAHKYTMEHFIEVVKNQEFLLLPANEIAKLLCSDDINVPNEETIFHALMHWVGHDAQNRQRDLAKLLSYIRLPLLSPQLLADLENSSMFTDDLECQKLLMEAMKYHLLPERRSMLQSPRTKPRKSTVGALYAVGGMDAAKGTTTIEKYDLRTNNWIHIGTMSGRRLQFGVAVVDNKLYVVGGRDGLKTLNTVECFNPVTKTWLVMPPMSTHRHGLGVATLEGPMYAVGGHDGWSYLNTVERWDPDGRQWNYVASMSTPRSTVGVVALNNKLYAIGGRDGSSCLKSMEYFDPHTNKWSLCAPMSKRRGGVGVATHNGYLYVVGGHDAPAPNHCSRLSDCVERYDPKSDSWSTVAPLSVPRDAVAVCPLGDKLYVVGGYDGHTYLNTVESYDAQKDEWNEEVPVNIGRAGACVVVVKLH", "length": 717, "header": "tr|A0A061HUW2-1|A0A061HUW2_CRIGR Isoform 1 of Kelch-like protein 4 isoform X2 OS=Cricetulus griseus OX=10029 GN=Klhl4 PE=4 SV=1 CANONICAL=A0A061HUW2-1" }, "locus": {} }, { "isoform_ac": "A0A061I0U8-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HUW2/entry#A0A061I0U8-1", "sequence": { "sequence": "MSVSGKKEFDVKQILRLRWRWFSHPSQGSPNTGSCLQQEGYEHRGTPVQGRLKNHSRDRNGLKKGNSPVHHNILTPVPGPAPTHQRVLQNWQQQNVIVHLQANEDTSKAVPEENLLKEAREKRSGDLEMMGDDNIEDSRARIYAEEPEEMNITSEDHFHSRNHADYTLSKMQNYLKEKKLCDVLLIAGHLKIPAHRLVLSAVSDYFAAMFTNDVLEARQEEVRMEGVDPNALNSLVQYAYTGMLQLREDTIENLLAAACLLQLTQVIDVCCNFLIKQLHPSNCLGILSFGDAQGCVELQNVAHKYTMEHFIEVVKNQEFLLLPANEIAKLLCSDDINVPNEETIFHALMHWVGHDAQNRQRDLAKLLSYIRLPLLSPQLLADLENSSMFTDDLECQKLLMEAMKYHLLPERRSMLQSPRTKPRKSTVGALYAVGGTTTIEKYDLRTNNWIHIGTMSGRRLQFGVAVVDNKLYVVGGRDGLKTLNTVECFNPVTKTWLVMPPMSTHRHGLGVATLEGPMYAVGGHDGWSYLNTVERWDPDGRQWNYVASMSTPRSTVGVVALNNKLYAIGGRDGSSCLKSMEYFDPHTNKWSLCAPMSKRRGGVGVATHNGYLYVVGGHDAPAPNHCSRLSDCVERYDPKSDSWSTVAPLSVPRDAVAVCPLGDKLYVVGGYDGHTYLNTVESYDAQKDEWNEEVPVNIGRAGACVVVVKLH", "length": 711, "header": "tr|A0A061I0U8-1|A0A061I0U8_CRIGR Computationally mapped isoform of Kelch-like protein 4 isoform X4 OS=Cricetulus griseus OX=10029 GN=Klhl4 PE=4 SV=1 CANONICAL=A0A061HUW2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GP93-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HUW2/entry#A0A9J7GP93-1", "sequence": { "sequence": "MSVSGKKEFDVKQILRLRWRWFSHPSQGSPNTGSCLQQEGYEHRGTPVQGRLKNHSRDRNGLKKGNSPVHHNILTPVPGPAPTHQRVLQNWQQQNVIVHLQANEDTSKAVPEENLLKEAREKRSGDLEMMGDDNIEDSRARIYAEEPEEMNITSEDHFHSRNHADYTLSKMQNYLKEKKLCDVLLIAGHLKIPAHRAVSDYFAAMFTNDVLEARQEEVRMEGVDPNALNSLVQYAYTGMLQLREDTIENLLAAACLLQLTQVIDVCCNFLIKQLHPSNCLGILSFGDAQGCVELQNVAHKYTMEHFIEVVKNQEFLLLPANEIAKLLCSDDINVPNEETIFHALMHWVGHDAQNRQRDLAKLLSYIRLPLLSPQLLADLENSSMFTDDLECQKLLMEAMKYHLLPERRSMLQSPRTKPRKSTVGALYAVGGMDAAKGTTTIEKYDLRTNNWIHIGTMSGRRLQFGVAVVDNKLYVVGGRDGLKTLNTVECFNPVTKTWLVMPPMSTHRHGLGVATLEGPMYAVGGHDGWSYLNTVERWDPDGRQWNYVASMSTPRSTVGVVALNNKLYAIGGRDGSSCLKSMEYFDPHTNKWSLCAPMSKRRGGVGVATHNGYLYVVGGHDAPAPNHCSRLSDCVERYDPKSDSWSTVAPLSVPRDAVAVCPLGDKLYVVGGYDGHTYLNTVESYDAQKDEWNEEVPVNIGRAGACVVVVKLH", "length": 713, "header": "tr|A0A9J7GP93-1|A0A9J7GP93_CRIGR Computationally mapped isoform of Kelch-like protein 4 isoform X3 OS=Cricetulus griseus OX=10029 GN=Klhl4 PE=4 SV=1 CANONICAL=A0A061HUW2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H535-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HUW2/entry#A0A9J7H535-1", "sequence": { "sequence": "MNITSEDHFHSRNHADYTLSKMQNYLKEKKLCDVLLIAGHLKIPAHRLVLSAVSDYFAAMFTNDVLEARQEEVRMEGVDPNALNSLVQYAYTGMLQLREDTIENLLAAACLLQLTQVIDVCCNFLIKQLHPSNCLGILSFGDAQGCVELQNVAHKYTMEHFIEVVKNQEFLLLPANEIAKLLCSDDINVPNEETIFHALMHWVGHDAQNRQRDLAKLLSYIRLPLLSPQLLADLENSSMFTDDLECQKLLMEAMKYHLLPERRSMLQSPRTKPRKSTVGALYAVGGMDAAKGTTTIEKYDLRTNNWIHIGTMSGRRLQFGVAVVDNKLYVVGGRDGLKTLNTVECFNPVTKTWLVMPPMSTHRHGLGVATLEGPMYAVGGHDGWSYLNTVERWDPDGRQWNYVASMSTPRSTVGVVALNNKLYAIGGRDGSSCLKSMEYFDPHTNKWSLCAPMSKRRGGVGVATHNGYLYVVGGHDAPAPNHCSRLSDCVERYDPKSDSWSTVAPLSVPRDAVAVCPLGDKLYVVGGYDGHTYLNTVESYDAQKDEWNEEVPVNIGRAGACVVVVKLH", "length": 568, "header": "tr|A0A9J7H535-1|A0A9J7H535_CRIGR Computationally mapped isoform of Kelch-like protein 4 isoform X5 OS=Cricetulus griseus OX=10029 GN=Klhl4 PE=4 SV=1 CANONICAL=A0A061HUW2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061HUW2", "url": "https://www.uniprot.org/uniprotkb/A0A061HUW2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061HUW2", "url": "https://www.uniprot.org/uniprotkb/A0A061HUW2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764135", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764135", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A061HUW2", "url": "https://www.uniprot.org/uniprotkb/A0A061HUW2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A061HUW2", "url": "https://www.uniprot.org/uniprotkb/A0A061HUW2" } ], "pmid": "" }, { "name": "intercellular bridge", "id": "GO:0045171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045171", "evidence": [ { "database": "UniProtKB", "id": "A0A061HUW2", "url": "https://www.uniprot.org/uniprotkb/A0A061HUW2" } ], "pmid": "" }, { "name": "mitotic spindle", "id": "GO:0072686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072686", "evidence": [ { "database": "UniProtKB", "id": "A0A061HUW2", "url": "https://www.uniprot.org/uniprotkb/A0A061HUW2" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A061HUW2", "url": "https://www.uniprot.org/uniprotkb/A0A061HUW2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 385, "end_pos": 387, "annotation": "n_glycosylation_sequon" }, { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061HUW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUW2" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 181, "end_pos": 248, "start_aa": "Cys", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 151, "end_pos": 153 }, { "start_pos": 385, "end_pos": 387 }, { "start_pos": 54, "end_pos": 56 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061HUW8-1", "uniprot_ac": "A0A061HUW8", "uniprot_id": "A0A061HUW8_CRIGR", "mass": { "chemical_mass": 32942.0, "monoisotopic_mass": 32942.0 }, "refseq": { "ac": "XP_035305527", "name": "transmembrane protein 74", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305527" }, "gene_names": [ { "name": "Tmem74", "type": "recommended", "evidence": [ { "id": "A0A061HUW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUW8" } ] }, { "name": "Tmem74", "type": "synonym", "evidence": [ { "id": "XP_035305527", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305527" } ] } ], "protein_names": [ { "name": "Transmembrane protein 74", "type": "synonym", "evidence": [ { "id": "A0A061HUW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HUW8/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 74", "type": "synonym", "evidence": [ { "id": "XP_035305527", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305527" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048603.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. 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"MEEADRILIHSLRQAGTAVPPEVQTLRAFTTELVVEAVVRCLRVISPTVGSSLSHLLPPAMSARFRLAMSLAQACMDLGYPLELGYQNFLYPSEPDLRDLLLFLAERLPTDASEDADQPAGDSAIFLRAIGSQIRDQLAVPWVPPLLRTPKLQYLQGSALQQSFHSTRLVLPELSSKGEPWEFQASPLLLPAPTQVPQLVRRAASLLEHHAIQLCQHVSRDCPGDEDRVCWAHRLPSQEDSRAAQQRLHKHLAEHLRQSWGPLGASTQVRDLGEMLQPWGVRNKTSTPKGSRFTHSEKFTFQLEPQAQATQIPDVPVTLQKPEQDTRAAQEQELESLREQLSSVNHSIEVVEADMKTLGINLMQVETECRQSELSVAEQEQALRLKSRAVELLPDGAANLAKLQLVVESSAQRVIHLASQWEKHRVPLLAEYRHLRKLQDCRELESSRRLAEIQELHQSVRAAAEEARRKEEVYKQLVSELETLPKDVSRLAYTQRILEIVGNIRKQKEEITKILSDTKELQKEINSLSGKLDRTFAVTDELVFKDAKKDDAVRKAYKYLAALHENCSQLIQTIEDTGTIMREIRDLEEQIETEMGKKTLSNLEKICEDYRALRQENAGLLGRVREA", "length": 627, "header": "tr|A0A061HUX4-1|A0A061HUX4_CRIGR Isoform 1 of Coiled-coil domain-containing protein 22 OS=Cricetulus griseus OX=10029 GN=Ccdc22 PE=3 SV=1 CANONICAL=A0A061HUX4-1" }, "isoforms": [ { "isoform_ac": "A0A061HUX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HUX4/entry#A0A061HUX4-1", "sequence": { "sequence": 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061HUX4", "url": "https://www.uniprot.org/uniprotkb/A0A061HUX4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757706", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757706", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cullin family protein binding", "id": "GO:0097602", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097602", "evidence": [ { "database": "UniProtKB", "id": "A0A061HUX4", "url": "https://www.uniprot.org/uniprotkb/A0A061HUX4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of ubiquitin-dependent protein catabolic process", "id": 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Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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"length": 1357, "header": "tr|A0A061HVD5-1|A0A061HVD5_CRIGR Isoform 1 of Pleckstrin homology domain-containing family G member 2 isoform X3 OS=Cricetulus griseus OX=10029 GN=Plekhg2 PE=4 SV=1 CANONICAL=A0A061HVD5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GMC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HVD5/entry#A0A9J7GMC9-1", "sequence": { "sequence": "MPEGARGLSLSKPSLRLGCGHQGEACDCAAVSDTPTAPAAPTMASLRGSGSSTSLSTVGSEGDPSPACPASTRPEPLPEPPIRLHLSPVGIQGSVKPSRLERVAKEIVETERAYVRDLRSIVEDYLGPLMDGRVLGLSMEQVGTLFANIEDIYEFSSELLEDLENSNSAGGIAECFVQRSEDFDIYTLYCMNYPSSLALLRELSLSPPATLWLQERQAQLRHSLPLQSFLLKPVQRILKYHLLLQELGKHWSEGPDTGGREMVEEAIVSMTAVAWYINDMKRKQEHAARLQEVQRRLGGWTGPELSAFGELVLEGTFRGGGGGGPRLRGGERLLFLFSRMLLVAKRRGHEYTYKGHIFCCNLSVTETPRDPLGFKVSDLTIPKHRHLLQAKNQEEKRLWIHCLQRLFFENHPASIPAKAKQVLLENSLHCAPKSKLIPEPPTAPLDSPRPRDARSFTPGRRNPAPSPRLSGSRRGRRQSEKSQVKHAGSEGELHPPPELQPAVSAPGPPEDLEDAGPPTLDPSGTSITEEILELLNQRGLRDPGPATHDIPKFPRDSRVPVESEPLPFQALPSRESSEEEEDEELEADEREPSPLHVLEGLEGSSSAEMPCMPSLSKIPNNMPSLPEIPEVPCLPSLSDIPGVFEMPCLSPMSSVPDIPSLASTPSFPCGSWLPGPLQEPAQPLATRRELLTGNNPGGGGLGEPPSESRVGQQEDEEGVVFPAVQTQDGAQVQGFPEELEYRSCSEIRSAWQALEQGQLARPGFPEPLLILEDSDLSGGSTSGKAGMPHSERSASRVRELARLYSERIQQMQRAETRASTNAPRRRPRVLAQPQPSPCPPQEEAEPGPLPAFGHVLVCELAFPLNCAQESVPLGPAALVQTAIPLSKQGDHLNAQGLNVLDLPKQDHLSSCIPPTPLPEQSDLENIQVPSTSPLPEQEEPPDIQVPASATLPDQSQVPATTSSAEHRNYMEIQVPSTTTCLPGQECHADFQMQATGALPKQEACASVRVLATPLLSKQESHEDSQSPASTPGGEEVGVSIDEGPAAVGGRAVSPLLVCTSNPDLQIPATTPLPLAPDPPDIEGPSALPLSAHGGRPDCCVPCSPLPSLSQDIQMPATVPMSQPQILTDIRAEAPPSFPKQEGAPDSLGPEPRLTDTPAPRLSPLLGQQNPTAGRVSAVTPLTEQGCSRDLQGLITTMELSKPRGHLVSPVAKSESSDVTPLQNPSLSTRQLLGPSAAALSRYLAASYISQSLARRQGPGGDGLVASQGPWSSSAPTSRAPSPPPQPQPPAPPARRLSYATTVSIQVGGGGRLRPAKAQVRLNHPALMAAPHPGACGPSQGPGGS", "length": 1344, "header": "tr|A0A9J7GMC9-1|A0A9J7GMC9_CRIGR Computationally mapped isoform of Pleckstrin homology domain-containing family G member 2 isoform X4 OS=Cricetulus griseus OX=10029 GN=Plekhg2 PE=4 SV=1 CANONICAL=A0A061HVD5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1043, "start_aa": "Thr", "end_pos": 1043, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1043", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 442, "start_aa": "Thr", "end_pos": 442, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr442", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 677, "start_aa": "Thr", "end_pos": 677, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr677", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 928, "start_aa": "Thr", "end_pos": 928, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr928", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061HVD5", "url": "https://www.uniprot.org/uniprotkb/A0A061HVD5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061HVD5", "url": "https://www.uniprot.org/uniprotkb/A0A061HVD5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761461", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761461", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A061HVD5", "url": "https://www.uniprot.org/uniprotkb/A0A061HVD5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A061HVD5", "url": "https://www.uniprot.org/uniprotkb/A0A061HVD5" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A061HVD5", "url": "https://www.uniprot.org/uniprotkb/A0A061HVD5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of actin filament polymerization", "id": "GO:0030833", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030833", "evidence": [ { "database": "UniProtKB", "id": "A0A061HVD5", "url": "https://www.uniprot.org/uniprotkb/A0A061HVD5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], 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"isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 442, 677, 928, 1043 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 361, "end_pos": 363 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", 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"A0A061HVE4", "uniprot_id": "A0A061HVE4_CRIGR", "mass": { "chemical_mass": 72277.0, "monoisotopic_mass": 72277.0 }, "refseq": { "ac": "XP_035305199", "name": "paraneoplastic antigen-like protein 8B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305199" }, "gene_names": [ { "name": "LOC113837381", "type": "recommended", "evidence": [ { "id": "A0A061HVE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVE4" } ] }, { "name": "LOC113837381", "type": "synonym", "evidence": [ { "id": "XP_035305199", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305199" } ] } ], "protein_names": [ { "name": "Paraneoplastic antigen-like protein 8B isoform X1", "type": "synonym", "evidence": [ { "id": "A0A061HVE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVE4/entry#names_and_taxonomy" } ] }, { "name": "paraneoplastic antigen-like protein 8B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035305199", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305199" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305199", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305199" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061HVE4", "url": "https://www.uniprot.org/uniprotkb/A0A061HVE4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113837381", "url": "https://www.uniprot.org/uniprotkb/A0A061HVE4", "locus": {} } ], "crossref": [ { "id": "113837381", "url": "https://www.ncbi.nlm.nih.gov/gene/113837381", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026523", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026523", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113837381", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113837381", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061HVE4", "url": "https://www.orthodb.org/?gene=A0A061HVE4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23095", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23095", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23095:SF45", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23095:SF45", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF20846", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20846", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305199", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305199", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061HVE4", "url": "https://www.uniprot.org/uniprotkb/A0A061HVE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061HVE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HVE4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9L4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9L4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9L4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTMNLLQDWCKELEVDIHRALLITGIPERLQQADIEATLRPKLEPLGNYRLRTVRAVTKEKAQAALVEFGADFDHSAIPIHIRGENGIWKIQSKDRGQDARVLRQMRRLLLDERPMDDFREIAIPLVLEAQAQAKGLGKEAKKAGSSGGAARNRRGRRGGKRRSRSHKFTVQKGKKRGRGGRRARSESDDSSDDSLGIVIEEIYAEDLSVDEDQRALYATLQAAAKELTKKWAFRGEQDEGEGPREFLALVTVTDKAKKEEIEKDLPGTESICLNIKDEKSGVPDLVALLAVRDTPVVEVDSEGEEGDEEEEEEEEEEEEEDDDDDDDSDGESLENGELGKEGLDNPEFVAIVAYTDPADPSAREEMLKIASVIETLGWGDKKDKKDVLPQVLSVMSKDTSGPRVKVEEAGRQVDAMVLRKAEEDGNLLECISTLAEAENCPKGKKSGLGLLRGWTAEGHQGGLLELVALLAAQDMVESVKEEEASRWGGGGGGGGSSSGGGSGGRKCDHSQSGLSDVLAFLASQENLESNEESDDDSDTESEGDSDDTDSEESEPGDSVSKKPRAKRARTGSKSQAPAGATAVSTASRARKTRRGGRGRGRGVTPEKKVGSGAATEDHAGNNNKKKKGSAGAGGARARASEAKGQPAAVPKSTRGKKARRGPRRAPKCR", "length": 670, "header": "tr|A0A061HVE4-1|A0A061HVE4_CRIGR Isoform 1 of Paraneoplastic antigen-like protein 8B isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC113837381 PE=3 SV=1 CANONICAL=A0A061HVE4-1" }, "isoforms": [ { "isoform_ac": "A0A061HVE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HVE4/entry#A0A061HVE4-1", "sequence": { "sequence": "MTMNLLQDWCKELEVDIHRALLITGIPERLQQADIEATLRPKLEPLGNYRLRTVRAVTKEKAQAALVEFGADFDHSAIPIHIRGENGIWKIQSKDRGQDARVLRQMRRLLLDERPMDDFREIAIPLVLEAQAQAKGLGKEAKKAGSSGGAARNRRGRRGGKRRSRSHKFTVQKGKKRGRGGRRARSESDDSSDDSLGIVIEEIYAEDLSVDEDQRALYATLQAAAKELTKKWAFRGEQDEGEGPREFLALVTVTDKAKKEEIEKDLPGTESICLNIKDEKSGVPDLVALLAVRDTPVVEVDSEGEEGDEEEEEEEEEEEEEDDDDDDDSDGESLENGELGKEGLDNPEFVAIVAYTDPADPSAREEMLKIASVIETLGWGDKKDKKDVLPQVLSVMSKDTSGPRVKVEEAGRQVDAMVLRKAEEDGNLLECISTLAEAENCPKGKKSGLGLLRGWTAEGHQGGLLELVALLAAQDMVESVKEEEASRWGGGGGGGGSSSGGGSGGRKCDHSQSGLSDVLAFLASQENLESNEESDDDSDTESEGDSDDTDSEESEPGDSVSKKPRAKRARTGSKSQAPAGATAVSTASRARKTRRGGRGRGRGVTPEKKVGSGAATEDHAGNNNKKKKGSAGAGGARARASEAKGQPAAVPKSTRGKKARRGPRRAPKCR", "length": 670, "header": "tr|A0A061HVE4-1|A0A061HVE4_CRIGR Isoform 1 of Paraneoplastic antigen-like protein 8B isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC113837381 PE=3 SV=1 CANONICAL=A0A061HVE4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H9L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HVE4/entry#A0A9J7H9L4-1", "sequence": { "sequence": "MTMNLLQDWCKELEVDIHRALLITGIPERLQQADIEATLRPKLEPLGNYRLRTVRAVTKEKAQAALVEFGADFDHSAIPIHIRGENGIWKIQSKDRGQDARVLRQMRRLLLDERPMDDFREIAIPLVLEAQAQAKGLGKEAKKAGSSGGAARNRRGRRGGKRRSRSHKFTVQKGKKRGRGGRRARSESDDSSDDSLGIVIEEIYAEDLSVDEDQRALYATLQAAAKELTKKWAFRGEQDEGEGPREFLALVTVTDKAKKEEIEKDLPGTESICLNIKDEKSGVPDLVALLAVRDTPEEDDDDDDDSDGESLENGELGKEGLDNPEFVAIVAYTDPADPSAREEMLKIASVIETLGWGDKKDKKDVLPQVLSVMSKDTSGPRVKVEEAGRQVDAMVLRKAEEDGNLLECISTLAEAENCPKGKKSGLGLLRGWTAEGHQGGLLELVALLAAQDMVESVKEEEASRWGGGGGGGGSSSGGGSGGRKCDHSQSGLSDVLAFLASQENLESNEESDDDSDTESEGDSDDTDSEESEPGDSVSKKPRAKRARTGSKSQAPAGATAVSTASRARKTRRGGRGRGRGVTPEKKVGSGAATEDHAGNNNKKKKGSAGAGGARARASEAKGQPAAVPKSTRGKKARRGPRRAPKCR", "length": 647, "header": "tr|A0A9J7H9L4-1|A0A9J7H9L4_CRIGR Computationally mapped isoform of Paraneoplastic antigen-like protein 8B isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC113837381 PE=3 SV=1 CANONICAL=A0A061HVE4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061HVE4", "url": "https://www.uniprot.org/uniprotkb/A0A061HVE4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061HVE4", "url": "https://www.uniprot.org/uniprotkb/A0A061HVE4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:113837381", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113837381", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061HVE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVE4" }, { "id": "PF20846", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20846" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Paraneoplastic antigen Ma-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 91, "start_aa": "Met", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061HVF5-1", "uniprot_ac": "A0A061HVF5", "uniprot_id": "A0A061HVF5_CRIGR", "mass": { "chemical_mass": 43431.0, "monoisotopic_mass": 43431.0 }, "refseq": { "ac": "XP_027288687", "name": "polyadenylate-binding protein 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288687" }, "gene_names": [ { "name": "Pabpc5", "type": "recommended", "evidence": [ { "id": "A0A061HVF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVF5" } ] }, { "name": "Pabpc5", "type": "synonym", "evidence": [ { "id": "XP_027288687", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288687" } ] } ], "protein_names": [ { "name": "Polyadenylate-binding protein 5", "type": "recommended", "evidence": [ { "id": "A0A061HVF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HVF5/entry#names_and_taxonomy" } ] }, { "name": "polyadenylate-binding protein 5", "type": "synonym", "evidence": [ { "id": "XP_027288687", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288687" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027288687.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027288687", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288687" } ] }, { "annotation": "Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo.", "evidence": [ { "database": "UniProtKB", "id": "A0A061HVF5", "url": "https://www.uniprot.org/uniprotkb/A0A061HVF5#function" }, { "database": "UniProtKB", "id": "ARBA00043929", "url": "https://www.uniprot.org/uniprotkb/ARBA00043929#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061HVF5", "url": "https://www.uniprot.org/uniprotkb/A0A061HVF5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pabpc5", "url": "https://www.uniprot.org/uniprotkb/A0A061HVF5", "locus": {} } ], "crossref": [ { "id": "cd12378", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12378", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12379", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12379", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12380", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12380", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100766161", "url": "https://www.ncbi.nlm.nih.gov/gene/100766161", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003954", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003954", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034364", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034364", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045305", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045305", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766161", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766161", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061HVF5", "url": "https://www.orthodb.org/?gene=A0A061HVF5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24012", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24012", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027288687", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288687", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061HVF5", "url": "https://www.uniprot.org/uniprotkb/A0A061HVF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061HVF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HVF5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSGEPNIAGKKKKYLKAALYVGDLGPEVTEDMLYKKFRPAGPLRFTRICRDPVTHSPLGYGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKHLDKSIDNRTLFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVWLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNLGDNMDDEKLKELFSEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQKSVLDLHGKTIDGKVLYVGRAQKKIERLAELRRRFERLKLKEKSRPPGVPIYIKNLDETIDDEKLKEEFSSFGSISRAKVMMEMGQGKGFAVVCFSSFEEATKAVDEMNGRVLGSKPLSVTLGQARHRW", "length": 382, "header": "tr|A0A061HVF5-1|A0A061HVF5_CRIGR Isoform 1 of Polyadenylate-binding protein 5 OS=Cricetulus griseus OX=10029 GN=Pabpc5 PE=4 SV=1 CANONICAL=A0A061HVF5-1" }, "isoforms": [ { "isoform_ac": "A0A061HVF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HVF5/entry#A0A061HVF5-1", "sequence": { "sequence": "MGSGEPNIAGKKKKYLKAALYVGDLGPEVTEDMLYKKFRPAGPLRFTRICRDPVTHSPLGYGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKHLDKSIDNRTLFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVWLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNLGDNMDDEKLKELFSEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQKSVLDLHGKTIDGKVLYVGRAQKKIERLAELRRRFERLKLKEKSRPPGVPIYIKNLDETIDDEKLKEEFSSFGSISRAKVMMEMGQGKGFAVVCFSSFEEATKAVDEMNGRVLGSKPLSVTLGQARHRW", "length": 382, "header": "tr|A0A061HVF5-1|A0A061HVF5_CRIGR Isoform 1 of Polyadenylate-binding protein 5 OS=Cricetulus griseus OX=10029 GN=Pabpc5 PE=4 SV=1 CANONICAL=A0A061HVF5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061HVF5", "url": "https://www.uniprot.org/uniprotkb/A0A061HVF5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061HVF5", "url": "https://www.uniprot.org/uniprotkb/A0A061HVF5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766161", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766161", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A061HVF5", "url": "https://www.uniprot.org/uniprotkb/A0A061HVF5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007651847", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651847" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061HVS3", "url": "https://www.uniprot.org/uniprotkb/A0A061HVS3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100757173", "url": "https://www.uniprot.org/uniprotkb/A0A061HVS3", "locus": {} } ], "crossref": [ { "id": "100757173", "url": "https://www.ncbi.nlm.nih.gov/gene/100757173", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757173", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757173", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061HVS3", "url": "https://www.orthodb.org/?gene=A0A061HVS3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11736", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11736", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11736:SF67", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11736:SF67", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01454", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01454", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007651847", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651847", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061HVS3", "url": "https://www.uniprot.org/uniprotkb/A0A061HVS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061HVS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HVS3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRAHKNKGQKSKGRSRAKHHQAHGDSQGAQLSVVGQSASPPSVQGSDLGAASSDARAVDENPRAFQAETYNQPICKDALTKKASMLVEFLLEKFQKSEEFTDEDMLKVVNKKYKTQFSDILRKSSSRMEMIFGMRLKKINPNSQSYAIVSKLGLSTDEILSGRRGLAKMGLLMTILGLIFTKGNRATEEDVWKFLGVLGVYAGKKHLIFGEPRKLITKDLVEQNYLEIHKMSEGKSTKYEFLWGDRSHVETSKMKVLEVWARINDTVPSFFPTPYEEALKDQMERAQQGSPAMGCPAAMARVHPMCMCCSSSHK", "length": 315, "header": "tr|A0A061HVS3-1|A0A061HVS3_CRIGR Isoform 1 of Melanoma-associated antigen B4 OS=Cricetulus griseus OX=10029 GN=LOC100757173 PE=4 SV=1 CANONICAL=A0A061HVS3-1" }, "isoforms": [ { "isoform_ac": "A0A061HVS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HVS3/entry#A0A061HVS3-1", "sequence": { "sequence": "MPRAHKNKGQKSKGRSRAKHHQAHGDSQGAQLSVVGQSASPPSVQGSDLGAASSDARAVDENPRAFQAETYNQPICKDALTKKASMLVEFLLEKFQKSEEFTDEDMLKVVNKKYKTQFSDILRKSSSRMEMIFGMRLKKINPNSQSYAIVSKLGLSTDEILSGRRGLAKMGLLMTILGLIFTKGNRATEEDVWKFLGVLGVYAGKKHLIFGEPRKLITKDLVEQNYLEIHKMSEGKSTKYEFLWGDRSHVETSKMKVLEVWARINDTVPSFFPTPYEEALKDQMERAQQGSPAMGCPAAMARVHPMCMCCSSSHK", "length": 315, "header": "tr|A0A061HVS3-1|A0A061HVS3_CRIGR Isoform 1 of Melanoma-associated antigen B4 OS=Cricetulus griseus OX=10029 GN=LOC100757173 PE=4 SV=1 CANONICAL=A0A061HVS3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305324", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305324" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061HVU2", "url": "https://www.uniprot.org/uniprotkb/A0A061HVU2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113837346", "url": "https://www.uniprot.org/uniprotkb/A0A061HVU2", "locus": {} } ], "crossref": [ { "id": "113837346", "url": "https://www.ncbi.nlm.nih.gov/gene/113837346", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050831", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050831", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113837346", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113837346", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061HVU2", "url": "https://www.orthodb.org/?gene=A0A061HVU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44427", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44427", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44427:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44427:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305324", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305324", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061HVU2", "url": "https://www.uniprot.org/uniprotkb/A0A061HVU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061HVU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HVU2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPAHSDRETLYSNGSLLIQNVTRNDTGTYAVRILWEGYVTYIASTEFHVHQPVTPPFIQVTNTTIKEKDPVSLTCISKDTGISIRWLFNGKRLELTDRMKLSQDNITLRIESFRKEDSGVYECEVSNPVSSKKSDSIQLDIMHA", "length": 145, "header": "tr|A0A061HVU2-1|A0A061HVU2_CRIGR Isoform 1 of Carcinoembryonic antigen-related cell adhesion molecule 3-like OS=Cricetulus griseus OX=10029 GN=LOC113837346 PE=3 SV=1 CANONICAL=A0A061HVU2-1" }, "isoforms": [ { "isoform_ac": "A0A061HVU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HVU2/entry#A0A061HVU2-1", "sequence": { "sequence": "MGPAHSDRETLYSNGSLLIQNVTRNDTGTYAVRILWEGYVTYIASTEFHVHQPVTPPFIQVTNTTIKEKDPVSLTCISKDTGISIRWLFNGKRLELTDRMKLSQDNITLRIESFRKEDSGVYECEVSNPVSSKKSDSIQLDIMHA", "length": 145, "header": "tr|A0A061HVU2-1|A0A061HVU2_CRIGR Isoform 1 of Carcinoembryonic antigen-related cell adhesion molecule 3-like OS=Cricetulus griseus OX=10029 GN=LOC113837346 PE=3 SV=1 CANONICAL=A0A061HVU2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 55, "start_aa": "Thr", "end_pos": 55, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr55", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027288763", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288763" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061HW88", "url": "https://www.uniprot.org/uniprotkb/A0A061HW88" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Armcx5", "url": "https://www.uniprot.org/uniprotkb/A0A061HW88", "locus": {} } ], "crossref": [ { "id": "100769784", "url": "https://www.ncbi.nlm.nih.gov/gene/100769784", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769784", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769784", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NPKACRC", "url": "https://omabrowser.org/oma/group/NPKACRC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061HW88", "url": "https://www.orthodb.org/?gene=A0A061HW88", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47081", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47081", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47081:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47081:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027288763", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288763", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061HW88", "url": "https://www.uniprot.org/uniprotkb/A0A061HW88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061HW88-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HW88-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIGSTTKAKGREESGASLKPGSKSLANAKEKAKSQTKKVVEAKPKEELGTQAEARDEAMARTQTVTHTEPETMTWKVKKKKDKTNTRVKDQTKTELRAEPGLVPHTKADDLPMSVVITVTKSEIRVDTGIETSIKYSSKASDKGSMKHISEIKKETLVRSGAGDKASIVINTTDEDEEYVCSWFWTGEEPSVGSWFWPKEETPLQVYQPPPKVEEEPEPTDNFDFTLKRKAAAWARGRFIVLVPVEEFEQSLPPEGNWTLVATLIETPLGIRPLTKIPPFEGPYFQTLAEIKNQIREREKYGPNPKTCRCKSRTFSLEPIEFDKLVALLKLTRDPFIHEIATMIMGISPAYPFTQDIVHDVGITVMIENFVNNPNAKNHSRTVNVSASADTSEEAKENEAHVDKVCRDILSCPLNCSVQVEELKLLASLSMKFENHHVIINYVRHFITLLSKGSVKLKFQILRVILYLSKNQANTRELISAEVLSSLVALFHKNESKANVLHIINIFENINFQFKKRAKLFTKEMFTKSELISIFQEAKQFDLKLQDLIDHSDPEVRDKIIRLILKL", "length": 567, "header": "tr|A0A061HW88-1|A0A061HW88_CRIGR Isoform 1 of Armadillo repeat-containing X-linked protein 5 OS=Cricetulus griseus OX=10029 GN=Armcx5 PE=4 SV=1 CANONICAL=A0A061HW88-1" }, "isoforms": [ { "isoform_ac": "A0A061HW88-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HW88/entry#A0A061HW88-1", "sequence": { "sequence": "MIGSTTKAKGREESGASLKPGSKSLANAKEKAKSQTKKVVEAKPKEELGTQAEARDEAMARTQTVTHTEPETMTWKVKKKKDKTNTRVKDQTKTELRAEPGLVPHTKADDLPMSVVITVTKSEIRVDTGIETSIKYSSKASDKGSMKHISEIKKETLVRSGAGDKASIVINTTDEDEEYVCSWFWTGEEPSVGSWFWPKEETPLQVYQPPPKVEEEPEPTDNFDFTLKRKAAAWARGRFIVLVPVEEFEQSLPPEGNWTLVATLIETPLGIRPLTKIPPFEGPYFQTLAEIKNQIREREKYGPNPKTCRCKSRTFSLEPIEFDKLVALLKLTRDPFIHEIATMIMGISPAYPFTQDIVHDVGITVMIENFVNNPNAKNHSRTVNVSASADTSEEAKENEAHVDKVCRDILSCPLNCSVQVEELKLLASLSMKFENHHVIINYVRHFITLLSKGSVKLKFQILRVILYLSKNQANTRELISAEVLSSLVALFHKNESKANVLHIINIFENINFQFKKRAKLFTKEMFTKSELISIFQEAKQFDLKLQDLIDHSDPEVRDKIIRLILKL", "length": 567, "header": "tr|A0A061HW88-1|A0A061HW88_CRIGR Isoform 1 of Armadillo repeat-containing X-linked protein 5 OS=Cricetulus griseus OX=10029 GN=Armcx5 PE=4 SV=1 CANONICAL=A0A061HW88-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061HW88", "url": "https://www.uniprot.org/uniprotkb/A0A061HW88" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061HW88", "url": "https://www.uniprot.org/uniprotkb/A0A061HW88" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769784", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769784", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B0V5-1", "protein_name": "Armadillo repeat containing X-linked 5", "gene_name": "ARMCX5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAMTREVSKMEAKTKTRVVAETKSKPLVEPSVVSQTKSKTMPVSKISAVIEYEVKAGAASEPNIRSFARADDKDNTQSRSQRRREASMKFRAGDGAGIVIESSDDEENACSWFWTGEEPSVGSWFWPEEETPFQVYEPPPKIPEKPKPTPKPKPELTIKQKAAAWSRARYCVLVPIEGGEGSLPPEGNWTLVETLIETPLGIRPLTKIPPYNGPYFQTLAEIKKQVKYREKYGPNPKTCRCKSRVFSLEPKEFDKLVALLKLTRDPFIHQIATMIMGISPAYPFTQDIIHDVGITVMIENLVNNPNVIEHPRALNKVDDNSGSSGQPKTGELYVNQVCKEIISSPLNSPVQLAGLKLLVQLSVKFEDHHMIINYIPDFLTLLNKGSVKTKFYVLKVFSRLSKNQANTRELISAKVLSSLVAPFNKNESKANILNIIEIFENINFQFKKKVKLFTKEEFTKSELISIFQEAKEFGQKLQDLAEHSDPEVRDKVIRLILKL", "length": 499 }, "evidence": [ { "id": "A0A061HW88", "url": "https://omabrowser.org/oma/group/A0A061HW88/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4A548-1", "protein_name": "Armadillo repeat containing, X-linked 5", "gene_name": "Armcx5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIGSKTKKKAREESGPSPKPGTNSPANAKGKGKGQTNKGGKAEPKVEWGNQAEARDGAVARTQPVVPTEPKTVTWKVKKKKDKTNTRVTAQAKTELLAEPALVPHTKSDALPPSVLITVTKSEVKVDTGGEPSVKGSAKANDKHSIKHKSEIKKEVCVRSRAGDKASNVNTTDEDDEDYVCSWFWTGEEPSVGSWFWPKEENSLQAYQPPPKVEEEPEPPDTFDFALKKKAAAWLRGRFIVLVPIEEPQPSLPPEGNWTLVATLIETPLGIRPLTKIPPYGGPYFQTLADLKNQIREKEKYGPNPKTCRCKSRTFSLEPVEFDKLVALLKLTRDPFIHEIATMIMGISPAYPFTQDIVHDVGITVLIENFVNNPNAKKYPRNLNLNANPDAPEEVRETEAHVNKVCRDILSCPLNCSVQVEELKLLVSLSVKFDYHHVVIYYVRYFISLLNKGSVKIKFQILRVILCLSKNQANTRELISAEVMSSLVAHFHKNESKANILHIIEIFENINFQFKKRAKLFTKEMFTKSELISIFREAKEFDQKLQDLTDHSDPDVRDKVIRLILKL", "length": 567 }, "evidence": [ { "id": "A0A061HW88", "url": "https://omabrowser.org/oma/group/A0A061HW88/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3UZB0-1", "protein_name": "Armadillo repeat-containing X-linked protein 5", "gene_name": "Armcx5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIGSKTKRKAREESGASSKPGTNSPANAKGKAKNQTTKAVKAEPKEEWGNQAEARDEAVARTQPAISTEPKTVTWKVKKKKDKTNARVMAQAKTELPAGPALVPHTKSDALPTSVVITVTKSEVKIDTGIEASLKGAAKATDKRSIKQKPEIKKEVCVKSRAGDKAKEVCVKSSAGDKAKEVCVKSRAGDKAKEVCVKSRAGDKASIVINTTDEDEDYVCSWFWTGEEPSVGSWFWPKEENPLQVYQPPPKVEEEPEPPDTFDYALKKKAAAWLRGRFIVLVPIEEPQPSLPPDGNWTLVATLIETPLGIRPLTKIPPYGGPYFQTLADLKNQIREKEKYGPNPNTCRCKSRTFSLEPVDFDKLVALLKLTRDPFIHEIATMIMGISPAYPFTQDIVHDVGITVMIENFVNNPNAKKYPRTLNINANPDAPEEVKETEAHVNKVCRDILCCPLNCSVQVEELKLLVSLSVKFDYHHVVIYYVRYFISLLNKGSVKIKFQILRVLLCLSKNQANTRELISAEVMSSLVALFHKNESKANILHIIEIFENINFQFKKRAKLFTKEMFTKSELISIFREAKEFDQKLQDLTDHSDPDVRDKVIRLILKL", "length": 606 }, "evidence": [ { "id": "A0A061HW88", "url": "https://omabrowser.org/oma/group/A0A061HW88/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6P1M9-1", "protein_name": "Armadillo repeat-containing X-linked protein 5", "gene_name": "ARMCX5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVDSGTEARARGKAEAGLQDGISGPATARVNGKTQAEAVAEAELKTESVTQAKAGDGAMTRTHTVTYREAMAVTREVIKVEDTTKTRVMVETKTKPLAERSIVPQTKSKAMPMSRVSTVTKSEVKVVAVIEANIRSYAKSHDKANTGSRPDRREETSIGMKSSDEDEENICSWFWTGEEPSVGSWFWPEEETSLQVYKPLPKIQEKPKPTHKPTLTIKQKVIAWSRARYIVLVPVEGGEQSLPPEGNWTLVETLIETPLGIRPLTKIPPYHGPYYQTLAEIKKQIRQREKYGPNPKACHCKSRGFSLEPKEFDKLVALLKLTKDPFIHEIATMIMGISPAYPFTQDIIHDVGITVMIENLVNNPNVKEHPGALSMVDDSSESSEEPKSGESYIHQVCKGIISCPLNSPVQLAGLKLLGHLSIKFEDHYVITSYIPDFLTLLNKGSVKTKFYVLKVFSCLSKNHANTRELISAKVLSSLVAPFNKNESKANILNIIEIFENINFQFKTKAKLFTKEKFTKSELISIFQEAKQFGQKLQDLAEHSDPEVRDKVIRLILKL", "length": 558 }, "evidence": [ { "id": "A0A061HW88", "url": "https://omabrowser.org/oma/group/A0A061HW88/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 415, "end_pos": 417, "annotation": "n_glycosylation_sequon" }, { "start_pos": 494, "end_pos": 496, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061HW88", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HW88" }, { "id": "PF04826", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04826" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Armadillo repeat-containing", "eco_id": "ECO_0000259", "start_pos": 317, "end_pos": 536, "start_aa": "Leu", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 171, "end_pos": 173 }, { "start_pos": 257, "end_pos": 259 }, { "start_pos": 378, "end_pos": 380 }, { "start_pos": 384, "end_pos": 386 }, { "start_pos": 415, "end_pos": 417 }, { "start_pos": 494, "end_pos": 496 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061HWF3-1", "uniprot_ac": "A0A061HWF3", "uniprot_id": "A0A061HWF3_CRIGR", "mass": { "chemical_mass": 52811.0, "monoisotopic_mass": 52811.0 }, "refseq": { "ac": "XP_027283454", "name": "ras-GEF domain-containing family member 1C isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283454" }, "gene_names": [ { "name": "Rasgef1c", "type": "recommended", "evidence": [ { "id": "A0A061HWF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HWF3" } ] }, { "name": "Rasgef1c", "type": "synonym", "evidence": [ { "id": "XP_027283454", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283454" } ] } ], "protein_names": [ { "name": "Ras-GEF domain-containing family member 1C isoform X2", "type": "synonym", "evidence": [ { "id": "A0A061HWF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HWF3/entry#names_and_taxonomy" } ] }, { "name": "ras-GEF domain-containing family member 1C isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027283454", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283454" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027283454", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283454" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061HWF3", "url": "https://www.uniprot.org/uniprotkb/A0A061HWF3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rasgef1c", "url": "https://www.uniprot.org/uniprotkb/A0A061HWF3", "locus": {} } ], "crossref": [ { "id": "cd00155", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00155", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06224", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06224", "database": "CDD", 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This record is derived from a genomic sequence (NW_003614673.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003509303.1. 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}, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061HY09-1", "uniprot_ac": "A0A061HY09", "uniprot_id": "A0A061HY09_CRIGR", "mass": { "chemical_mass": 104216.0, "monoisotopic_mass": 104216.0 }, "refseq": { "ac": "XP_035301997", "name": "RIPOR family member 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301997" }, "gene_names": [ { "name": "Ripor3", "type": "recommended", "evidence": [ { "id": "A0A061HY09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HY09" } ] }, { "name": "Ripor3", "type": "synonym", "evidence": [ { "id": "XP_035301997", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301997" } ] } ], "protein_names": [ { "name": "RIPOR family member 3", "type": "synonym", "evidence": [ { "id": "XP_035301997", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301997" }, { "id": "A0A061HY09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HY09/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035301997", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301997" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061HY09", "url": "https://www.uniprot.org/uniprotkb/A0A061HY09" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ripor3", "url": "https://www.uniprot.org/uniprotkb/A0A061HY09", "locus": {} } ], "crossref": [ { "id": "100757599", "url": "https://www.ncbi.nlm.nih.gov/gene/100757599", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757599", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757599", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ELDYLCG", "url": "https://omabrowser.org/oma/group/ELDYLCG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061HY09", "url": "https://www.orthodb.org/?gene=A0A061HY09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15829", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15829", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15829:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15829:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15903", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15903", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035301997", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301997", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061HY09", "url": "https://www.uniprot.org/uniprotkb/A0A061HY09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061HY09-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HY09-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVRLRFLSPGDVGAVGTVGRSASFAGFSAQSRRVSKSINRNSVRSRLPAKPSKAYGTLRKGSLCLDPRPQQVKKIFDALKRGLREHLCEQQAELDYLCGRHTDSQRSSRLAFYYDLDKQTRLVERHIRKVEFHISKVDELYEGYCIQWRLRDGASNMQRAFSNGTQSRASRESLQELGRSLQECMEDMCLIEGALEVHLGEFHVKMKGLVGYARLCPGDQYEVLMRLGRQRWRLKGRIEPDDSQTWDEEEKAFVPTVHENLEIKVTELRGLSSMVVGAVTCDIADFFTARPQLVVVDITELGTIKLQLELLWNPLDSECRLVSPSPTGRFSMGSRKGSLYTWTPPSTPSFRDKYYLSVLQQPAQQALLLGGPRATSILGYLSDSELQGPCLRSRSQELLEMDSFSSEDPRDTETSTSASTSDVGFLPMPVGPTASIDKGTREEPPPLGLLPGLAHPAGGVLVEQPGWRDLGGERLALLQDAPIHSPMVPRSQKGQEEEDVGDGVERPVQEVLDLLRSANPTQPQLRELEYQVLGLRDRLKPRGVPPEPMSVQSLMDCILESFAFLNADLASDELSLFGGSQAPERDSPPPPRPSLKVSPSELTAGAPELDMLLTVHLQICKALLQKLASPNLSRMVQDCLLEEAEQQRQVLEVLSDLDFEQVSKARSVEEIIPQAPHRNGGLALWRGCTQPGAVLACSASTLLSQLKRTFLHRVRGKYPGQLEIVCRRLLEQVLNCGGLLATAGLQEEQMVTWFQFHSYLQRQSVSDLEKHLNLLCKEVTLIEELHCAGPAKALRKLHGKRLGQLQPLPQTLQAWALLQLDGSPRVCRAARARLASAARNRRFREKALLYYTNALNDSDATLQQAACMALQQLGGVESVEHIASLCRSDLEAVRVSAREATLSFGEKGRLAFEKMDKLQSEQEIYQEADVEITIF", "length": 936, "header": "tr|A0A061HY09-1|A0A061HY09_CRIGR Isoform 1 of RIPOR family member 3 OS=Cricetulus griseus OX=10029 GN=Ripor3 PE=3 SV=1 CANONICAL=A0A061HY09-1" }, "isoforms": [ { "isoform_ac": "A0A061HY09-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HY09/entry#A0A061HY09-1", "sequence": { "sequence": "MSVRLRFLSPGDVGAVGTVGRSASFAGFSAQSRRVSKSINRNSVRSRLPAKPSKAYGTLRKGSLCLDPRPQQVKKIFDALKRGLREHLCEQQAELDYLCGRHTDSQRSSRLAFYYDLDKQTRLVERHIRKVEFHISKVDELYEGYCIQWRLRDGASNMQRAFSNGTQSRASRESLQELGRSLQECMEDMCLIEGALEVHLGEFHVKMKGLVGYARLCPGDQYEVLMRLGRQRWRLKGRIEPDDSQTWDEEEKAFVPTVHENLEIKVTELRGLSSMVVGAVTCDIADFFTARPQLVVVDITELGTIKLQLELLWNPLDSECRLVSPSPTGRFSMGSRKGSLYTWTPPSTPSFRDKYYLSVLQQPAQQALLLGGPRATSILGYLSDSELQGPCLRSRSQELLEMDSFSSEDPRDTETSTSASTSDVGFLPMPVGPTASIDKGTREEPPPLGLLPGLAHPAGGVLVEQPGWRDLGGERLALLQDAPIHSPMVPRSQKGQEEEDVGDGVERPVQEVLDLLRSANPTQPQLRELEYQVLGLRDRLKPRGVPPEPMSVQSLMDCILESFAFLNADLASDELSLFGGSQAPERDSPPPPRPSLKVSPSELTAGAPELDMLLTVHLQICKALLQKLASPNLSRMVQDCLLEEAEQQRQVLEVLSDLDFEQVSKARSVEEIIPQAPHRNGGLALWRGCTQPGAVLACSASTLLSQLKRTFLHRVRGKYPGQLEIVCRRLLEQVLNCGGLLATAGLQEEQMVTWFQFHSYLQRQSVSDLEKHLNLLCKEVTLIEELHCAGPAKALRKLHGKRLGQLQPLPQTLQAWALLQLDGSPRVCRAARARLASAARNRRFREKALLYYTNALNDSDATLQQAACMALQQLGGVESVEHIASLCRSDLEAVRVSAREATLSFGEKGRLAFEKMDKLQSEQEIYQEADVEITIF", "length": 936, "header": "tr|A0A061HY09-1|A0A061HY09_CRIGR Isoform 1 of RIPOR family member 3 OS=Cricetulus griseus OX=10029 GN=Ripor3 PE=3 SV=1 CANONICAL=A0A061HY09-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 348, "start_aa": "Thr", "end_pos": 348, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr348", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 434, "start_aa": "Thr", "end_pos": 434, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr434", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061HY09", "url": "https://www.uniprot.org/uniprotkb/A0A061HY09" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061HY09", "url": "https://www.uniprot.org/uniprotkb/A0A061HY09" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757599", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757599", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YNZ6-1", "protein_name": "RIPOR family member 3", "gene_name": "FAM65C", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSVKLTFVSSGDGGGISRSCSFTGFSTVQSRKLAKSLGRSSVRSRMSLKSPKAYSSLQKGAVIWDPKPLQVKKIFEALKKGLNEYLEAHQTELDYLSDRHKDTKRNSRLAFYYDLDKQIRSVERYIRKLEFHISKVEELYEAYCIQCRLRDGAANMKHAFSLSPSTKASRESLVELYKNFQECTEDMCFIEGALEVHLGEFHLKMKGLVGFARLCPGDQYEVFVRLGRQKWKLKGKIETDDSQTWDEEEKIFIPNLHEQFEIKVTELRGLATVLVGVVTCDSINFFTTKPQAIIVDITELGTIKLQLEVLWNPFDAENLFLSPGTTAKFSVGSRKSSLYNWTPPNTPSFREKYYPSALQQRQNQGDVSGEAQPPSILSYLAACDFGVHERSKPHSPAETSEGDSFSNEDQRGTESRITAPVLDHRTLPLVIIQETCAEEQHPLPNHATLDILKTPCVDTFPSNPSNFLSHGKGGRHLNQTRNHHLTEQESISQKSLNAANGIKLDGCTKSIDKTLQEVLNLLKFHGVGQAQLEKLEYQVSTLRDKLKLRTLNHKHSSVESLMVETVLESFNFLNADCSADEVSLFGSIRTASISTYNDNMFQSLSCDMKTETSDVTTGDDNLDVLLITHLKLCKALLQKLRLPNVAQIVQENILEEVSEQLQVLGDVLDMSVEEIIQKTKKKKHYLKIWSDVAEPGSILFASAERFRHVLKYTLALKVKEKYPGQLEAVLRKLLEQIVTCDGLLPSPCLQTEPVTLFQFYSYLEKHQITSLEKHIGRLAKEVMLIEELQCPGRLKTLKKLKGKRLNRLQPLPQSLWLLGILQLDDNHRVSKAATSCLSRAAANKNFREKALLFYTDVLVGCDARLQQAACLALKNLRGIESIEQVAHLCQSETEDVRNAARETTLSFGEKGRQAFEKMDRICCELRFINKYGTGVPRLGREINIVQCRFASNSKQAPVALWH", "length": 962 }, "evidence": [ { "id": "A0A061HY09", "url": "https://omabrowser.org/oma/group/A0A061HY09/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A1L3T7-1", "protein_name": "RIPOR family member 3", "gene_name": "Ripor3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRLRFLSQGDAGAVGTVGRSASFAGFSSAQSRRLSKSINRNSVRSRLPAKSSKAYRTLRKGSLCLDPRPQQVKKIFDALKRGLREHLCEQQAELDYLCGRHTDTQRGSRLAFYYDLDKQLRLVERHIRKVEFHISKVDELYEAYCIQWRLRDGASNMQRAFSNSTQSRASRESLQELGRSLQECLEDMCLIEGTLEGHLGEFQVKMKGLVGYARLCPGDQYEVLMRLGRQRWRLKGRIEPDDSQTWDEEERVFVPTVHENLEIKVTELRGLSSMVVGAVTCDVADFFMARPQLVVVDITELGTIKLQLELLWNPLDSECRLVSPSPTGRFSMGSRKGSLYTWTPPSTPSFRDKYYLSLLQQPVQQSLLLGGPKATSILGYLSDSELQGPRLRSRSQELLEMDSFSSEDPRDTETSTSASTSDVGFLPVPVGSAACTEEETREGPPPLGLLPGLAHPARGVLVERPGWRDLGGERLALLQDAPIHSPMVPRSRKGQEDGDVGDGVEGPVQEVLDLLRSADPAQPQLRELEYQVLGLRERLKPRGVQPEPVSAQSLMDCILESFAFLNADLASDELSLFGGSQAPERDSPPPPRPSLKVSPSELTAGAPELDTLLTVHLQVCKALLQKLASPNLSRMVEDCLLEEAVQQRQVLEVLSDLDLEQVSKARSVEEIIPQASHRKGGLALWQGCTQPGGVLACPASTLLSQLKKTFLHRVRGKYPGQLEIVCRRLLEQVVGCGGLLVPAGLQEEQVVTWFQFHSYLQRQSISDLEKHLAQLTKEVTLIEELSCAGPAKALRKLHGKCLSQLQPLPQTLQAWALLQLDGPPRLCRAARTRLASAARNKRFREKALLYYTNALNDSDAKVQQAACVALQQLGGIESCEQIVSLCQSDLEAVRVAAREATLSFGEKGRLAFEKMDKLHSEQEAFCQEADVEITIF", "length": 938 }, "evidence": [ { "id": "A0A061HY09", "url": "https://omabrowser.org/oma/group/A0A061HY09/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZX40-1", "protein_name": "RIPOR family member 3", "gene_name": "Ripor3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVRLRFLSPGEAGAVGTVGRSASFAGFSSAQSRRVSKSINRNSVRSRLPAKSSKAYGTLRKGSLCLDPRPQQVKKIFDALKRGLREHLCEQQAELDYLCRCHTDTQRSSRLAFYYDLDKQMRMVERHIRKVEFHISKVDELYEGYCIQWRLRDGASNMQRAFSNSTQSRASRESLQELGRSLQECLEDMCLIEGTLEGHLGEFHVKMKGLVGYARLCPGDQYEVLMRLGRQRWRLKGRIEPDDSQTWDEEERVFVPTVHENLEIKVTELRGLGSMVVGAVTCDVADFFTARPQLVVVDITELGTIKLQLELLWNPLDSECRLVSPSPTGRFSVGSRKGSLYTWTPPSTPSFRDKYYLSVLQQPMQQALLLGGPRATSILGYLSDSELQGPRLRSRSQELLEMDSFSSEDPRDTETSTSASTSDVGFLPMPVAPTACIEEETREEPPPLGLLPGLTHPAGGVLVEQPGWRDLRGERLDLLLDDPIHSPTVPRSRKGQEDGGAGDGVEGPVQEVLDLLRSADPAQPQLRELEYQVLGLRERLKPRGVQPEPVSAQSLMDCILESFAFLNADLASDELSLFGGSQALERDSPPPPRPSLKVSPSELTAGTPELDTLLTVHLQVCKALLQKLASPNLSRMVQDCLLEEAVQQRQVLEVLSDLDLEQVSKAKSVEEIIPQASQRKGGLALWQGCTQPGGVLACPASTLLSQLKKTFLHRVRGKYPGQLEIVCRRLLEQVLGCGGLFVTAGLQDEQVVTWFQFHSYLQRQNISDLEKHLTQLTKEVTLIEELNCAGPAKALRKLHGKRLSQLQPLPQTLQAWARLQLDGPPRLCRAARMRLASAARNKRFREKALLYYTNALNDSDSKLQQAACMALQQLGGVESIEQIVSLCQSDLEAVRAAAREATLSFGEKGRLAFEKMDKLHAEQEAFCQEADVEITIF", "length": 938 }, "evidence": [ { "id": "A0A061HY09", "url": "https://omabrowser.org/oma/group/A0A061HY09/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96MK2-1", "protein_name": "RIPOR family member 3", "gene_name": "RIPOR3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVRLRFLSPGDTGAVGVVGRSASFAGFSSAQSRRIAKSINRNSVRSRMPAKSSKMYGTLRKGSVCADPKPQQVKKIFEALKRGLKEYLCVQQAELDHLSGRHKDTRRNSRLAFYYDLDKQTRCVERHIRKMEFHISKVDELYEDYCIQCRLRDGASSMQRAFARCPPSRAARESLQELGRSLHECAEDMWLIEGALEVHLGEFHIRMKGLVGYARLCPGDHYEVLMRLGRQRWKLKGRIESDDSQTWDEEEKAFIPTLHENLDIKVTELRGLGSLAVGAVTCDIADFFTTRPQVIVVDITELGTIKLQLEVQWNPFDTESFLVSPSPTGKFSMGSRKGSLYNWTPPSTPSFRERYYLSVLQQPTQQALLLGGPRATSILSYLSDSDLRGPSLRSQSQELPEMDSFSSEDPRDTETSTSASTSDVGFLPLTFGPHASIEEEAREDPLPPGLLPEMAHLSGGPFAEQPGWRNLGGESPSLPQGSLFHSGTASSSQNGHEEGATGDREDGPGVALEGPLQEVLELLRPTDSTQPQLRELEYQVLGFRDRLKPCRARQEHTSAESLMECILESFAFLNADFALDELSLFGGSQGLRKDRPLPPPSSLKASSRELTAGAPELDVLLMVHLQVCKALLQKLASPNLSRLVQECLLEEVAQQKHVLETLSVLDFEKVGKATSIEEIIPQASRTKGCLKLWRGCTGPGRVLSCPATTLLNQLKKTFQHRVRGKYPGQLEIACRRLLEQVVSCGGLLPGAGLPEEQIITWFQFHSYLQRQSVSDLEKHFTQLTKEVTLIEELHCAGQAKVVRKLQGKRLGQLQPLPQTLRAWALLQLDGTPRVCRAASARLAGAVRNRSFREKALLFYTNALAENDARLQQAACLALKHLKGIESIDQTASLCQSDLEAVRAAARETTLSFGEKGRLAFEKMDKLCSEQREVFCQEADVEITIF", "length": 946 }, "evidence": [ { "id": 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This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027287756", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287756" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061HY55", "url": "https://www.uniprot.org/uniprotkb/A0A061HY55" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rnf113a", "url": "https://www.uniprot.org/uniprotkb/A0A061HY55", "locus": {} } ], "crossref": [ { "id": "cd16539", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16539", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100763475", "url": "https://www.ncbi.nlm.nih.gov/gene/100763475", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763475", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763475", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061HY55", "url": "https://www.orthodb.org/?gene=A0A061HY55", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12930", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12930", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12930:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12930:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00642", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00642", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027287756", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287756", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061HY55", "url": "https://www.uniprot.org/uniprotkb/A0A061HY55", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061HY55-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HY55-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEQLSPGSSAGQVCTFLFKKPGRKGAAGRRKRRHCDEGSGDSGSSSDEGSAVVRPEKKQATHNPMIQKTRGSGKQRANYGGLSSEDENEQEQLGVVYKSTRSAKPVGPEDMGATAVYELDTEKERDAQSIFERSQKIQEELRGKEDDKIYRGINNYQKYVKPKDTSMGNASSGMVRKGPIRAPEHLRATVRWDYQPDICKDYKETGFCGFGDSCKFLHDRSDYKHGWQIERELDEGRYGVYEEENYEVGSDDEEIPFKCFICRQTFQNPVVTKCRHYFCEKCALQHFRTTSRCYVCDQQTNGVFNPAKELIAKLGKHRTEAPGGASDFLEDPEEESPMPTI", "length": 342, "header": "tr|A0A061HY55-1|A0A061HY55_CRIGR Isoform 1 of E3 ubiquitin-protein ligase RNF113A OS=Cricetulus griseus OX=10029 GN=Rnf113a PE=4 SV=1 CANONICAL=A0A061HY55-1" }, "isoforms": [ { "isoform_ac": "A0A061HY55-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HY55/entry#A0A061HY55-1", "sequence": { "sequence": "MAEQLSPGSSAGQVCTFLFKKPGRKGAAGRRKRRHCDEGSGDSGSSSDEGSAVVRPEKKQATHNPMIQKTRGSGKQRANYGGLSSEDENEQEQLGVVYKSTRSAKPVGPEDMGATAVYELDTEKERDAQSIFERSQKIQEELRGKEDDKIYRGINNYQKYVKPKDTSMGNASSGMVRKGPIRAPEHLRATVRWDYQPDICKDYKETGFCGFGDSCKFLHDRSDYKHGWQIERELDEGRYGVYEEENYEVGSDDEEIPFKCFICRQTFQNPVVTKCRHYFCEKCALQHFRTTSRCYVCDQQTNGVFNPAKELIAKLGKHRTEAPGGASDFLEDPEEESPMPTI", "length": 342, "header": "tr|A0A061HY55-1|A0A061HY55_CRIGR Isoform 1 of E3 ubiquitin-protein ligase RNF113A OS=Cricetulus griseus OX=10029 GN=Rnf113a PE=4 SV=1 CANONICAL=A0A061HY55-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061HY55", "url": "https://www.uniprot.org/uniprotkb/A0A061HY55" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061HY55", "url": "https://www.uniprot.org/uniprotkb/A0A061HY55" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763475", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763475", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "snoRNA splicing", "id": "GO:0034247", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034247", "evidence": [ { "database": "UniProtKB", "id": "A0A061HY55", "url": "https://www.uniprot.org/uniprotkb/A0A061HY55" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A061HY55", "url": "https://www.uniprot.org/uniprotkb/A0A061HY55" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "U2-type spliceosomal complex", "id": "GO:0005684", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005684", "evidence": [ { "database": "UniProtKB", "id": "A0A061HY55", "url": "https://www.uniprot.org/uniprotkb/A0A061HY55" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061HY55", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HY55" }, { "id": "PS50103", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50103" } ], "ann_type": 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], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061HYI4-1", "uniprot_ac": "A0A061HYI4", "uniprot_id": "A0A061HYI4_CRIGR", "mass": { "chemical_mass": 51987.0, "monoisotopic_mass": 51987.0 }, "refseq": { "ac": "XP_027288897", "name": "XK-related protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288897" }, "gene_names": [ { "name": "Xkrx", "type": "recommended", "evidence": [ { "id": "A0A061HYI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HYI4" } ] }, { "name": "Xkrx", "type": "synonym", "evidence": [ { "id": "XP_027288897", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288897" } ] } ], "protein_names": [ { "name": "XK-related protein", "type": "recommended", "evidence": [ { "id": "A0A061HYI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HYI4/entry#names_and_taxonomy" } ] }, { "name": "XK-related protein 2 isoform X1", "type": "synonym", 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This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027288897", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288897" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061HYI4", "url": "https://www.uniprot.org/uniprotkb/A0A061HYI4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Xkrx", "url": "https://www.uniprot.org/uniprotkb/A0A061HYI4", "locus": {} } ], "crossref": [ { "id": "100770991", "url": "https://www.ncbi.nlm.nih.gov/gene/100770991", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018629", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018629", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051773", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051773", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770991", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770991", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061HYI4", "url": "https://www.orthodb.org/?gene=A0A061HYI4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GPM2", "url": "https://www.orthodb.org/?gene=A0A9J7GPM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14297", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14297", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14297:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14297:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09815", "url": 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"MDRVYEIPEEPNVVPVSSLGEDVIRGPNPRFTFPFSILFSTFLYCGEAASALYMVRIYRKNNETFWMTYTFSFFMFSSIMVQLTLIFVHRDLAKDRPLSLFMHLILLGPVIRCLEAMIKYLTLWKKEGQEEPYVSLTRKKMLIDGQEVLIEWEVGHSIRTLAMHRNAYKRMSQIQAFLGSVPQLTYQLYVTLISAEVPLGRAVLMVFSLISVTYGATLCNMLAIQIKYDDYKIRLGPLEVLCITIWRTLEITSRLMILVLFSATLKLKAVPFLVLNFLIILFEPWVKFWRSGAQMPNNIEKNFSRVGTLVVLISVTILYAGINFSCWSAMQLKLADRDLVDKGQNWGHMGLHYSVRLVENVVMVLVFKFLGVKVLLNYCHSLIAVQLIIAYLISIGFMLLFFQYLHPLRSLFTHNVVDYLHCVCCRRHHRERAENEEPSLEAETRQSIV", "length": 449, "header": "tr|A0A061HYI4-1|A0A061HYI4_CRIGR Isoform 1 of XK-related protein OS=Cricetulus griseus OX=10029 GN=Xkrx PE=3 SV=1 CANONICAL=A0A061HYI4-1" }, "isoforms": [ { "isoform_ac": "A0A061HYI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HYI4/entry#A0A061HYI4-1", "sequence": { "sequence": "MDRVYEIPEEPNVVPVSSLGEDVIRGPNPRFTFPFSILFSTFLYCGEAASALYMVRIYRKNNETFWMTYTFSFFMFSSIMVQLTLIFVHRDLAKDRPLSLFMHLILLGPVIRCLEAMIKYLTLWKKEGQEEPYVSLTRKKMLIDGQEVLIEWEVGHSIRTLAMHRNAYKRMSQIQAFLGSVPQLTYQLYVTLISAEVPLGRAVLMVFSLISVTYGATLCNMLAIQIKYDDYKIRLGPLEVLCITIWRTLEITSRLMILVLFSATLKLKAVPFLVLNFLIILFEPWVKFWRSGAQMPNNIEKNFSRVGTLVVLISVTILYAGINFSCWSAMQLKLADRDLVDKGQNWGHMGLHYSVRLVENVVMVLVFKFLGVKVLLNYCHSLIAVQLIIAYLISIGFMLLFFQYLHPLRSLFTHNVVDYLHCVCCRRHHRERAENEEPSLEAETRQSIV", "length": 449, "header": "tr|A0A061HYI4-1|A0A061HYI4_CRIGR Isoform 1 of XK-related protein OS=Cricetulus griseus OX=10029 GN=Xkrx PE=3 SV=1 CANONICAL=A0A061HYI4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GN60-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HYI4/entry#A0A9J7GN60-1", "sequence": { "sequence": "MLLHWRPWIYHQAVLMVFSLISVTYGATLCNMLAIQIKYDDYKIRLGPLEVLCITIWRTLEITSRLMILVLFSATLKLKAVPFLVLNFLIILFEPWVKFWRSGAQMPNNIEKNFSRVGTLVVLISVTILYAGINFSCWSAMQLKLADRDLVDKGQNWGHMGLHYSVRLVENVVMVLVFKFLGVKVLLNYCHSLIAVQLIIAYLISIGFMLLFFQYLHPLRSLFTHNVVDYLHCVCCRRHHRERAENEEPSLEAETRQSIV", "length": 260, "header": "tr|A0A9J7GN60-1|A0A9J7GN60_CRIGR Computationally mapped isoform of XK-related protein OS=Cricetulus griseus OX=10029 GN=Xkrx PE=3 SV=1 CANONICAL=A0A061HYI4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GPM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HYI4/entry#A0A9J7GPM2-1", "sequence": { "sequence": "MDISPGDLAKDRPLSLFMHLILLGPVIRCLEAMIKYLTLWKKEGQEEPYVSLTRKKMLIDGQEVLIEWEVGHSIRTLAMHRNAYKRMSQIQAFLGSVPQLTYQLYVTLISAEVPLGRAVLMVFSLISVTYGATLCNMLAIQIKYDDYKIRLGPLEVLCITIWRTLEITSRLMILVLFSATLKLKAVPFLVLNFLIILFEPWVKFWRSGAQMPNNIEKNFSRVGTLVVLISVTILYAGINFSCWSAMQLKLADRDLVDKGQNWGHMGLHYSVRLVENVVMVLVFKFLGVKVLLNYCHSLIAVQLIIAYLISIGFMLLFFQYLHPLRSLFTHNVVDYLHCVCCRRHHRERAENEEPSLEAETRQSIV", "length": 365, "header": "tr|A0A9J7GPM2-1|A0A9J7GPM2_CRIGR Computationally mapped isoform of XK-related protein OS=Cricetulus griseus OX=10029 GN=Xkrx PE=3 SV=1 CANONICAL=A0A061HYI4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H9C8-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HYI4/entry#A0A9J7H9C8-1", "sequence": { "sequence": "MKWRCLEAMIKYLTLWKKEGQEEPYVSLTRKKMLIDGQEVLIEWEVGHSIRTLAMHRNAYKRMSQIQAFLGSVPQLTYQLYVTLISAEVPLGRAVLMVFSLISVTYGATLCNMLAIQIKYDDYKIRLGPLEVLCITIWRTLEITSRLMILVLFSATLKLKAVPFLVLNFLIILFEPWVKFWRSGAQMPNNIEKNFSRVGTLVVLISVTILYAGINFSCWSAMQLKLADRDLVDKGQNWGHMGLHYSVRLVENVVMVLVFKFLGVKVLLNYCHSLIAVQLIIAYLISIGFMLLFFQYLHPLRSLFTHNVVDYLHCVCCRRHHRERAENEEPSLEAETRQSIV", "length": 341, "header": "tr|A0A9J7H9C8-1|A0A9J7H9C8_CRIGR Computationally mapped isoform of XK-related protein OS=Cricetulus griseus OX=10029 GN=Xkrx PE=3 SV=1 CANONICAL=A0A061HYI4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K2W1-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HYI4/entry#A0A9J7K2W1-1", "sequence": { "sequence": "MDISPGCLEAMIKYLTLWKKEGQEEPYVSLTRKKMLIDGQEVLIEWEVGHSIRTLAMHRNAYKRMSQIQAFLGSVPQLTYQLYVTLISAEVPLGRAVLMVFSLISVTYGATLCNMLAIQIKYDDYKIRLGPLEVLCITIWRTLEITSRLMILVLFSATLKLKAVPFLVLNFLIILFEPWVKFWRSGAQMPNNIEKNFSRVGTLVVLISVTILYAGINFSCWSAMQLKLADRDLVDKGQNWGHMGLHYSVRLVENVVMVLVFKFLGVKVLLNYCHSLIAVQLIIAYLISIGFMLLFFQYLHPLRSLFTHNVVDYLHCVCCRRHHRERAENEEPSLEAETRQSIV", "length": 343, "header": "tr|A0A9J7K2W1-1|A0A9J7K2W1_CRIGR Computationally mapped isoform of XK-related protein OS=Cricetulus griseus OX=10029 GN=Xkrx PE=3 SV=1 CANONICAL=A0A061HYI4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061HYI4", "url": "https://www.uniprot.org/uniprotkb/A0A061HYI4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061HYI4", "url": "https://www.uniprot.org/uniprotkb/A0A061HYI4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770991", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770991", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A061HYI4", "url": "https://www.uniprot.org/uniprotkb/A0A061HYI4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 302, "end_pos": 304, "annotation": "n_glycosylation_sequon" }, { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 302, "end_pos": 304 }, { "start_pos": 323, "end_pos": 325 }, { "start_pos": 62, "end_pos": 64 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061HYL4-1", "uniprot_ac": "A0A061HYL4", "uniprot_id": "A0A061HYL4_CRIGR", "mass": { "chemical_mass": 50586.0, "monoisotopic_mass": 50586.0 }, "refseq": { "ac": "XP_007646713", "name": "properdin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646713" }, "gene_names": [ { "name": "Cfp", "type": "recommended", "evidence": [ { "id": "A0A061HYL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HYL4" } ] }, { "name": "Cfp", "type": "synonym", "evidence": [ { "id": "XP_007646713", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646713" } ] } ], "protein_names": [ { "name": "Properdin isoform X1", "type": "synonym", "evidence": [ { "id": "A0A061HYL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HYL4/entry#names_and_taxonomy" } ] }, { "name": "properdin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007646713", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646713" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614457.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007646713", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646713" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061HYL4", "url": "https://www.uniprot.org/uniprotkb/A0A061HYL4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cfp", "url": "https://www.uniprot.org/uniprotkb/A0A061HYL4", "locus": {} } ], "crossref": [ { "id": "100763603", "url": "https://www.ncbi.nlm.nih.gov/gene/100763603", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052065", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052065", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054019", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054019", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763603", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763603", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CQACRSP", "url": "https://omabrowser.org/oma/group/CQACRSP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061HYL4", "url": "https://www.orthodb.org/?gene=A0A061HYL4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22906", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22906", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22906:SF43", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22906:SF43", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18487", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18487", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22195", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22195", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007646713", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646713", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061HYL4", "url": "https://www.uniprot.org/uniprotkb/A0A061HYL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061HYL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HYL4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JSK2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JSK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSK2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLAGMQAPPTLLLLLLTLPATGSDPVFCFTKYEESSGKCKGLLGGDVSVEDCCLNAAYAFQEHGGGPCQACRSPRWSPWSSWAPCSVTCSEGSQLRHRRCVGRGGQCSEKVAPRTLEWQLQACEDQPCCPEIGGWSEWGPWGPCSVTCSKGTRTRQRLCDNPAPKCGGHCPEEAQQSQACDTQKVCPTHGAWAAWGPWSSCSGSCLGGTEQPKETRSRSCSAPAPSHQPPGKPCLGSAYEHRGCSGLPPCPVPGGWGPWSPVSPCSVTCGLGQTLERRTCDHPVPRHGGLFCAGDATRTHICNTATPCPVNGEWEEWGKWSHCSRVNMKSISCEEIPGQQSRTRSCGGRKFNGQRCSGNYQHIRHCYDIHNCFLKGTWSQWSSWGLCTPPCGPNPTRVRQRLCTPLLPKFSPTVSMVEGQGEKNVTFWGTPRPQCEALQGQKLMVEEKRPCLHVPVCKDPEEEKP", "length": 465, "header": "tr|A0A061HYL4-1|A0A061HYL4_CRIGR Isoform 1 of Properdin isoform X1 OS=Cricetulus griseus OX=10029 GN=Cfp PE=4 SV=1 CANONICAL=A0A061HYL4-1" }, "isoforms": [ { "isoform_ac": "A0A061HYL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HYL4/entry#A0A061HYL4-1", "sequence": { "sequence": "MLAGMQAPPTLLLLLLTLPATGSDPVFCFTKYEESSGKCKGLLGGDVSVEDCCLNAAYAFQEHGGGPCQACRSPRWSPWSSWAPCSVTCSEGSQLRHRRCVGRGGQCSEKVAPRTLEWQLQACEDQPCCPEIGGWSEWGPWGPCSVTCSKGTRTRQRLCDNPAPKCGGHCPEEAQQSQACDTQKVCPTHGAWAAWGPWSSCSGSCLGGTEQPKETRSRSCSAPAPSHQPPGKPCLGSAYEHRGCSGLPPCPVPGGWGPWSPVSPCSVTCGLGQTLERRTCDHPVPRHGGLFCAGDATRTHICNTATPCPVNGEWEEWGKWSHCSRVNMKSISCEEIPGQQSRTRSCGGRKFNGQRCSGNYQHIRHCYDIHNCFLKGTWSQWSSWGLCTPPCGPNPTRVRQRLCTPLLPKFSPTVSMVEGQGEKNVTFWGTPRPQCEALQGQKLMVEEKRPCLHVPVCKDPEEEKP", "length": 465, "header": "tr|A0A061HYL4-1|A0A061HYL4_CRIGR Isoform 1 of Properdin isoform X1 OS=Cricetulus griseus OX=10029 GN=Cfp PE=4 SV=1 CANONICAL=A0A061HYL4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JSK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HYL4/entry#A0A9J7JSK2-1", "sequence": { "sequence": "MLTTGTSLLGKRSAQIKEGLLCKRGQRQCSKCLLECKLLRRYCCYCLPCQPQVQTLCSASPSMKSPLGSAKACLGEMSAWKTAVSMLPMPSRSMVVVPVRHAEIGGWSEWGPWGPCSVTCSKGTRTRQRLCDNPAPKCGGHCPEEAQQSQACDTQKVCPTHGAWAAWGPWSSCSGSCLGGTEQPKETRSRSCSAPAPSHQPPGKPCLGSAYEHRGCSGLPPCPVPGGWGPWSPVSPCSVTCGLGQTLERRTCDHPVPRHGGLFCAGDATRTHICNTATPCPVNGEWEEWGKWSHCSRVNMKSISCEEIPGQQSRTRSCGGRKFNGQRCSGNYQHIRHCYDIHNCFLKGTWSQWSSWGLCTPPCGPNPTRVRQRLCTPLLPKFSPTVSMVEGQGEKNVTFWGTPRPQCEALQGQKLMVEEKRPCLHVPVCKDPEEEKP", "length": 437, "header": "tr|A0A9J7JSK2-1|A0A9J7JSK2_CRIGR Computationally mapped isoform of Properdin isoform X2 OS=Cricetulus griseus OX=10029 GN=Cfp PE=4 SV=1 CANONICAL=A0A061HYL4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061HYL4", "url": "https://www.uniprot.org/uniprotkb/A0A061HYL4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061HYL4", "url": "https://www.uniprot.org/uniprotkb/A0A061HYL4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763603", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763603", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QHH9-1", "protein_name": "Complement factor properdin", "gene_name": "CFP", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPTQRQAPQLLLLPLLLLTLPATGSDPVLCFTQYEESSGKCKGLLGGGVSLEDCCLNADYAFQETSSKFCMPCRPPQWSPWSAWAPCSVTCTEGSQLRHRRCVGWGGQCPENVELGTLQWQLQACENQPCCPEMGGWSSWGPWAPCSATCSRGTRTRRRACDRPTPKCGGHCPGEAQESEDCDTQQVCPTHGAWAAWGPWGPCQSTCKGGPSEPVERRKRTCTAPEPSTKPPGNPCSGSANDQRMCSGLPPCPVAGGWGPWGAVSPCPVTCGLGQTREQRSCDHPVPQHGGPFCVGEAFRTHICNTAVPCPVDGEWGLWGEWSNCVRRGIKHISCQEIPGQQTRSRICKGRKFDGRRCLGEQQDIRHCYSIQRCPLKEASWSEWSTWGLCIPPCGPSPVRTRQRLCQPKLPNFPPTITPVEGQGEKNVTFWGKPLVKCDVLQGQHMMVEEKRPCLHAPPCNEP", "length": 463 }, "evidence": [ { "id": "A0A061HYL4", "url": "https://omabrowser.org/oma/group/A0A061HYL4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8M1NF67-1", "protein_name": "Uncharacterized protein LOC100149189 precursor", "gene_name": "si:ch73-237c6.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": 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RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027287749", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287749" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061HYM2", "url": "https://www.uniprot.org/uniprotkb/A0A061HYM2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100765912", "url": "https://www.uniprot.org/uniprotkb/A0A061HYM2", "locus": {} } ], "crossref": [ { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100765912", "url": "https://www.ncbi.nlm.nih.gov/gene/100765912", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765912", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765912", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061HYM2", "url": "https://www.orthodb.org/?gene=A0A061HYM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47465", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47465", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47465:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47465:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027287749", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287749", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061HYM2", "url": "https://www.uniprot.org/uniprotkb/A0A061HYM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061HYM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HYM2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERQNANYLLHEGLDEDEEKLNGVKAPVVLLAGEGRNEKESGQGQPGQGAAAAEGEGAGELSGEGPSAAGAEGLVDDRSQEDRGTSGGEQNEGQPWEPFCEVMGVAENVQPVSVLVRQRCFHYKFTQWQLQELERFFQQSHYISAEVRKQLARWIGVTEARVQNWFKGRREQYRRDQKL", "length": 179, "header": "tr|A0A061HYM2-1|A0A061HYM2_CRIGR Isoform 1 of Rhox homeobox family member 2 OS=Cricetulus griseus OX=10029 GN=LOC100765912 PE=4 SV=1 CANONICAL=A0A061HYM2-1" }, "isoforms": [ { "isoform_ac": "A0A061HYM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HYM2/entry#A0A061HYM2-1", "sequence": { "sequence": "MERQNANYLLHEGLDEDEEKLNGVKAPVVLLAGEGRNEKESGQGQPGQGAAAAEGEGAGELSGEGPSAAGAEGLVDDRSQEDRGTSGGEQNEGQPWEPFCEVMGVAENVQPVSVLVRQRCFHYKFTQWQLQELERFFQQSHYISAEVRKQLARWIGVTEARVQNWFKGRREQYRRDQKL", "length": 179, "header": "tr|A0A061HYM2-1|A0A061HYM2_CRIGR Isoform 1 of Rhox homeobox family member 2 OS=Cricetulus griseus OX=10029 GN=LOC100765912 PE=4 SV=1 CANONICAL=A0A061HYM2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027274856", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274856" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061HYM6", "url": "https://www.uniprot.org/uniprotkb/A0A061HYM6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ccdc185", "url": "https://www.uniprot.org/uniprotkb/A0A061HYM6", "locus": {} } ], "crossref": [ { "id": "100754743", "url": "https://www.ncbi.nlm.nih.gov/gene/100754743", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029090", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029090", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754743", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754743", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061HYM6", "url": "https://www.orthodb.org/?gene=A0A061HYM6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33663", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33663", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33663:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33663:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15558", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15558", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027274856", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274856", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061HYM6", "url": "https://www.uniprot.org/uniprotkb/A0A061HYM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061HYM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HYM6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGFHLFSRPYGELGEPLPGGEPEFAAPLGWPEPSLSPWARTPGAEIETEVPWGHQKCSSAARSRRRGSMSLPRESHSLTHVARRPADRARKHRSGSRQLDEACGEAPTKSSRTWQQQQPPPPDQPCPSYPAAPGVSSPPYPGGAFSPQSAGTLPLEKTHNGDRWAVPVYRHVGLWSPSSVLTDKSSGHSLEFEFRKQSTQKRGSGDRTESLANQYSQPSTSCKETSSQQAQVLKSKLDEAEISSRDQKILALVLSRLKKAQKMRELQQQAAVAWEELKRSDKKVHMTLERERRLLLQQSQEQWQGQKEQHKSRRDHEQLRQGYEQQGERRDRQEKSTIQAQAESQSRWPEQPDNPENGDLDKLDRVHAQAEHLKQCQMQRLQEQERVLQSLRDLNRLQMQKKLEVTCHKRQQHLPEESQKKVPENNLSSSIINFQARKVLMDCQAKAEELLRKLSLEQSSQSSQDVQEDLAKERHREQQGKAQKEAEQFQRVRWRTEEAEERRRQERQRVLAELAEQKIRQARCHEHKTSKDRVQHLQELSVLRERNNHILKLKAEKEEKCHIEGIKEAIKKKEQRVEQMTRWKDPIFQEFQKVPSASKTDRCFDYVAAETQLPAHHLSGIY", "length": 623, "header": "tr|A0A061HYM6-1|A0A061HYM6_CRIGR Isoform 1 of Coiled-coil domain-containing protein 185 OS=Cricetulus griseus OX=10029 GN=Ccdc185 PE=4 SV=1 CANONICAL=A0A061HYM6-1" }, "isoforms": [ { "isoform_ac": "A0A061HYM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HYM6/entry#A0A061HYM6-1", "sequence": { "sequence": "MAGFHLFSRPYGELGEPLPGGEPEFAAPLGWPEPSLSPWARTPGAEIETEVPWGHQKCSSAARSRRRGSMSLPRESHSLTHVARRPADRARKHRSGSRQLDEACGEAPTKSSRTWQQQQPPPPDQPCPSYPAAPGVSSPPYPGGAFSPQSAGTLPLEKTHNGDRWAVPVYRHVGLWSPSSVLTDKSSGHSLEFEFRKQSTQKRGSGDRTESLANQYSQPSTSCKETSSQQAQVLKSKLDEAEISSRDQKILALVLSRLKKAQKMRELQQQAAVAWEELKRSDKKVHMTLERERRLLLQQSQEQWQGQKEQHKSRRDHEQLRQGYEQQGERRDRQEKSTIQAQAESQSRWPEQPDNPENGDLDKLDRVHAQAEHLKQCQMQRLQEQERVLQSLRDLNRLQMQKKLEVTCHKRQQHLPEESQKKVPENNLSSSIINFQARKVLMDCQAKAEELLRKLSLEQSSQSSQDVQEDLAKERHREQQGKAQKEAEQFQRVRWRTEEAEERRRQERQRVLAELAEQKIRQARCHEHKTSKDRVQHLQELSVLRERNNHILKLKAEKEEKCHIEGIKEAIKKKEQRVEQMTRWKDPIFQEFQKVPSASKTDRCFDYVAAETQLPAHHLSGIY", "length": 623, "header": "tr|A0A061HYM6-1|A0A061HYM6_CRIGR Isoform 1 of Coiled-coil domain-containing protein 185 OS=Cricetulus griseus OX=10029 GN=Ccdc185 PE=4 SV=1 CANONICAL=A0A061HYM6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"MRPVQSRVPESRYWLHVLRWDQSPSLTGLAFCVSSSSVPPTDRKPPTPTSVPITGLDQSVCAPSTCSYLETTTSSHAKISRSMSLGDSEGLVTPEPSRSLHKPLSMGELASLGQEPQAIPTIVTLTSSIEGQDPAMPSWGNHEARASLKLPLSSVCGQLLSSPPLEPPITCVWSQDSVDVQPGVTATVASFPAPSPVDASTPRLHSSVFLPRTSASGPLIPPGHPNSLQLLETRSRVPSSTAALLEPTPDMPGSPGHCGEPGLPAEVLPPALLELGSIRSVSHRLQAVFQEALDLYRMLVSSNQLGAEQQQAQTELASAFQWIHSQLEASNWMAAANTAPPQTLPSPGLPSSPTLCLLASPNLQALLEHYSELLVQAVKRKARGD", "length": 385, "header": "tr|A0A9J7GJX5-1|A0A9J7GJX5_CRIGR Computationally mapped isoform of WD repeat-containing protein 62-like isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC113837640 PE=4 SV=1 CANONICAL=A0A061HYQ0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061HYQ0", "url": "https://www.uniprot.org/uniprotkb/A0A061HYQ0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061HYQ0", "url": "https://www.uniprot.org/uniprotkb/A0A061HYQ0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:113837640", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113837640", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "A0A061HYQ0", "url": "https://www.uniprot.org/uniprotkb/A0A061HYQ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061HYQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HYQ0" }, { "id": "PF24795", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24795" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MABP1/WRD62 coiled-coil", "eco_id": "ECO_0000259", "start_pos": 309, "end_pos": 421, "start_aa": "Pro", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"A0A061HYY6-1", "uniprot_ac": "A0A061HYY6", "uniprot_id": "A0A061HYY6_CRIGR", "mass": { "chemical_mass": 56352.0, "monoisotopic_mass": 56352.0 }, "refseq": { "ac": "XP_003497713", "name": "zinc finger and BTB domain-containing protein 37 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497713" }, "gene_names": [ { "name": "Zbtb37", "type": "recommended", "evidence": [ { "id": "A0A061HYY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HYY6" } ] }, { "name": "Zbtb37", "type": "synonym", "evidence": [ { "id": "XP_003497713", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497713" } ] } ], "protein_names": [ { "name": "Zinc finger and BTB domain-containing protein 37 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A061HYY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HYY6/entry#names_and_taxonomy" } ] }, { "name": "zinc finger and BTB domain-containing protein 37 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003497713", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497713" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613658.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003497713", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497713" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061HYY6", "url": "https://www.uniprot.org/uniprotkb/A0A061HYY6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Zbtb37", "url": "https://www.uniprot.org/uniprotkb/A0A061HYY6", "locus": {} } ], "crossref": [ { "id": "cd18222", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18222", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100774939", "url": "https://www.ncbi.nlm.nih.gov/gene/100774939", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774939", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774939", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PMTERHR", "url": "https://omabrowser.org/oma/group/PMTERHR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061HYY6", "url": "https://www.orthodb.org/?gene=A0A061HYY6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12874", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12874", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003497713", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497713", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061HYY6", "url": "https://www.uniprot.org/uniprotkb/A0A061HYY6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061HYY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HYY6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LVG3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LVG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVG3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTMEKSGNIQLEIPDFSNSVLSHLNQLRMQGRLCDIVVNVQGQAFRAHKVVLAASSPYFRDHMSLNEMSTVSISVIKNPTVFEELLSFCYTGRICLQLADIISYLTAASFLQMQHIIDKCTQILEGIHFKINVAEVEAELSQTRTKHPERPPESHRVTPTLNRSLSPRHNAAKGNWRGQVSAVLDIREFSPPEESTSPQIIEQSSDVESRESILRINRAGQWYVETGLADQGARSGDEVRVLGAVHIKTENLEEWLGPENQPSGEDGSSAEEVTAMVIDTTGHGSIGQESYSLGSLEAKVARPTSSEVDRFSPSGSVVSMTERYRARSESPGRMDEPKQLSSQVEESAMMGVSGYVEYLREQEVSERWFRYNPRLTCIYCAKSFNQKGSLDRHMRLHMGITPFVCRMCGKKYTRKDQLEYHIRKHTGNKPFHCHVCGKSFPFQAILNQHFRKNHPGCIIPLEGPHSISPETTVTSRQAEEGSPTQEETVAPGESAQGSVSTTGPD", "length": 505, "header": "tr|A0A061HYY6-1|A0A061HYY6_CRIGR Isoform 1 of Zinc finger and BTB domain-containing protein 37 isoform X1 OS=Cricetulus griseus OX=10029 GN=Zbtb37 PE=4 SV=1 CANONICAL=A0A061HYY6-1" }, "isoforms": [ { "isoform_ac": "A0A061HYY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HYY6/entry#A0A061HYY6-1", "sequence": { "sequence": "MTMEKSGNIQLEIPDFSNSVLSHLNQLRMQGRLCDIVVNVQGQAFRAHKVVLAASSPYFRDHMSLNEMSTVSISVIKNPTVFEELLSFCYTGRICLQLADIISYLTAASFLQMQHIIDKCTQILEGIHFKINVAEVEAELSQTRTKHPERPPESHRVTPTLNRSLSPRHNAAKGNWRGQVSAVLDIREFSPPEESTSPQIIEQSSDVESRESILRINRAGQWYVETGLADQGARSGDEVRVLGAVHIKTENLEEWLGPENQPSGEDGSSAEEVTAMVIDTTGHGSIGQESYSLGSLEAKVARPTSSEVDRFSPSGSVVSMTERYRARSESPGRMDEPKQLSSQVEESAMMGVSGYVEYLREQEVSERWFRYNPRLTCIYCAKSFNQKGSLDRHMRLHMGITPFVCRMCGKKYTRKDQLEYHIRKHTGNKPFHCHVCGKSFPFQAILNQHFRKNHPGCIIPLEGPHSISPETTVTSRQAEEGSPTQEETVAPGESAQGSVSTTGPD", "length": 505, "header": "tr|A0A061HYY6-1|A0A061HYY6_CRIGR Isoform 1 of Zinc finger and BTB domain-containing protein 37 isoform X1 OS=Cricetulus griseus OX=10029 GN=Zbtb37 PE=4 SV=1 CANONICAL=A0A061HYY6-1" }, "locus": {} }, { "isoform_ac": "A0A8C2LVG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HYY6/entry#A0A8C2LVG3-1", "sequence": { "sequence": "MTMEKSGNIQLEIPDFSNSVLSHLNQLRMQGRLCDIVVNVQGQAFRAHKVVLAASSPYFRDHMSLNEMSTVSISVIKNPTVFEELLSFCYTGRICLQLADIISYLTAASFLQMQHIIDKCTQILEGIHFKINVAEVEAELSQTRTKHPERPPESHRVTPTLNRSLSPRHNAAKGNWRGQVSAVLDIREFSPPEESTSPQIIEQSSDVESRESILRINRAGQWYVETGLADQGARSGDEVRVLGAVHIKTENLEEWLGPENQPSGEDGSSAEEVTAMVIDTTGHGSIGQESYSLGSLEAKVARPTSSEVDR", "length": 310, "header": "tr|A0A8C2LVG3-1|A0A8C2LVG3_CRIGR Computationally mapped isoform of Zinc finger and BTB domain-containing protein 37 isoform X2 OS=Cricetulus griseus OX=10029 GN=Zbtb37 PE=4 SV=1 CANONICAL=A0A061HYY6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 158, "start_aa": "Thr", "end_pos": 158, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr158", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061HYY6", "url": "https://www.uniprot.org/uniprotkb/A0A061HYY6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061HYY6", "url": "https://www.uniprot.org/uniprotkb/A0A061HYY6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774939", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774939", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480L9D6-1", "protein_name": "Zinc finger and BTB domain containing 37", "gene_name": "ZBTB37", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEKGGNIQLEIPDFSNSVLSHLNQLRMQGRLCDIVVNVQGQAFRAHKVVLAASSPYFRDHMSLNEMSTVSISVIKNPTVFEQLLSFCYTGRICLQLADIISYLTAASFLQMQHIIDKCTQILEGIHFKINVAEVEAELSQTRTKHPEGPPESHRVTPNLNRSLSPRHNTPKGNRRGQVSTVLDIRELSPPEESTSPQIIEQSSDVESREPILRINRAGQWYVETGVADRGARSDDEVRVLGAVHIKTENLEEWLGPENQPSGEDGSSAEEVTAMVIDTTGHGSVGQENYSLGSSGAKVARPTSSEIDRFSPSGSVVPLTERHRARSESPGRMDEPKQPSSQVEESAMMGVSGYVEYLREQEVSERWFRYNPRLTCIYCAKSFNQKGSLDRHMRLHMGITPFVCRMCGKKYTRKDQLEYHIRKHTGNKPFHCHVCGKSFPFQAILNQHFRKNHPGCIPLEGPHSISPETTVTSRGQAEEESPSQEETVASGETAPGSVSTTGPD", "length": 503 }, "evidence": [ { "id": "A0A061HYY6", "url": "https://omabrowser.org/oma/group/A0A061HYY6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0YAS8-1", "protein_name": "Zinc finger and BTB domain containing 37", "gene_name": "ZBTB37", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLPLTLQGCTPATETAMEKSGNIQLEIPDFSNSVLSHLNQLRMQGRLCDIVVNVQGQAFRAHKVVLAASSPYFRDHMSLNEMSTVSISVIKNPSVFEQLLSFCYTGRICLQLADIISYLTAASFLQMQHIIDKCTQILEGIHFKINVAEVEAELSQTRTKHQERPPESHRVTPNLNRSLSPRHNTLKGSRLGQVSTVLDIRELSPPAESTSPQIIEQSSDVESREPILRINRAGQWYVETGMGDRGGRNDDDVRVLGGVRIKTENLEEWLGTENQPSGEDGSSAEEVTAMVIDTTGHGSMSQETYALGSSGAKVARPTSSEIDRFSPSGSMVAVTERYRSKSESPGRMDEPKQPSSQGEESAMFGVSGYVEYLREQEVSERWFRYNPRLTCIYCAKSFNQKGSLDRHMRLHMGITPFVCRMCGKKYTRKDQLEYHIRKHTGNKPFHCHVCGKSFPFQAILNQHFRKNHPGCVPLEGPHSISPETTVTSRGQAEEESPPQEEAVAVGETAQGSVSTTGPD", "length": 519 }, "evidence": [ { "id": "A0A061HYY6", "url": "https://omabrowser.org/oma/group/A0A061HYY6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZGJ3-1", "protein_name": "Zinc finger and BTB domain containing 37", "gene_name": "Zbtb37", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTMEKSGNIQLEIPDFSNSVLSHLNQLRMQGRLCDIVVNVQGQAFRAHKVVLAASSPYFRDHMSLNEMSTVSISVIKNPTVFEQLLSFCYTGRICLQLADIISYLTAASFLQMQHIIDKCTQILEGIHFKINVAEVEAELSQTRTKHPERPPESHRVTPNLTRSLSPRHNASKGNWRGQVSAVLDIRELSPPEESTSPQIIEQSSDVEGREPILRINRAGQWYVETGIADQGPQSGDEVRVLGAVHIKTENLEEWLGPENQPSGEDGSSAEEVAAMVIDTTGHGSVGQESYTLGSSGAKVARPTSSEVDRFSPSGSVVSMTERHRARSESPGRMDEPKQLSSQVEESAMMGVSAYVEYLREQEVSERWFRYNPRLTCIYCAKSFNQKGSLDRHMRLHMGITPFVCRMCGKKYTRKDQLEYHIRKHTGNKPFHCHVCGKSFPFQAILNQHFRKNHPGCIPLEGPHSISPETTVTSRQAEEGSPSHEETVAPGESAQGSVSTTGPD", "length": 504 }, "evidence": [ { "id": "A0A061HYY6", "url": "https://omabrowser.org/oma/group/A0A061HYY6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1N518-1", "protein_name": "Zinc finger and BTB domain containing 37", "gene_name": "ZBTB37", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEKSGNIQLEIPDFSNSVLSHLNQLRMQGRLCDIVVNVQGQAFRAHKVVLAASSPYFRDHMSLNEMSTVSISVIKNPTVFEQLLSFCYTGRICLQLADIISYLTAASFLQMQHIIDKCTQILEGIHFKINVAEVEAELSQTRTKHAEGPPESHRVTPNLNRSLSPRHNTLKGNRRGQVSAVLDIRELSPPEESTSPQIIEQSSDVESREPILRINRAGQWYVETGVADRGARSDDEVRVLGAVHIKTENLEEWLGPENQPSGEDGSSAEEVTAMVIDTTGHGSVGQENYALGSSGAKVARPTSSEIDRFSPSGSVVPLTERHRARSESPGRMDEPKQPTSQVEESAMMGVSGYVEYLREQEVSERWFRYNPRLTCIYCAKSFNQKGSLDRHMRLHMGITPFVCRMCGKKYTRKDQLEYHIRKHTGNKPFHCHVCGKSFPFQAILNQHFRKNHPGCIPLEGPHSISPETTVTSRGQAEEESPSQEETVASGETAQGSVSTTGPD", "length": 503 }, "evidence": [ { "id": "A0A061HYY6", "url": "https://omabrowser.org/oma/group/A0A061HYY6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5TC79-1", "protein_name": "Zinc finger and BTB domain-containing protein 37", "gene_name": "ZBTB37", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEKGGNIQLEIPDFSNSVLSHLNQLRMQGRLCDIVVNVQGQAFRAHKVVLAASSPYFRDHMSLNEMSTVSISVIKNPTVFEQLLSFCYTGRICLQLADIISYLTAASFLQMQHIIDKCTQILEGIHFKINVAEVEAELSQTRTKHQERPPESHRVTPNLNRSLSPRHNTPKGNRRGQVSAVLDIRELSPPEESTSPQIIEPSSDVESREPILRINRAGQWYVETGVADRGGRSDDEVRVLGAVHIKTENLEEWLGPENQPSGEDGSSAEEVTAMVIDTTGHGSVGQENYTLGSSGAKVARPTSSEVDRFSPSGSVVPLTERHRARSESPGRMDEPKQPSSQVEESAMMGVSGYVEYLREQEVSERWFRYNPRLTCIYCAKSFNQKGSLDRHMRLHMGITPFVCRMCGKKYTRKDQLEYHIRKHTGNKPFHCHVCGKSFPFQAILNQHFRKNHPGCIPLEGPHSISPETTVTSRGQAEEESPSQEETVAPGEAVQGSVSTTGPD", "length": 503 }, "evidence": [ { "id": "A0A061HYY6", "url": "https://omabrowser.org/oma/group/A0A061HYY6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A061HYY6", "url": "https://www.uniprot.org/uniprotkb/A0A061HYY6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A061HYY6", "url": "https://www.uniprot.org/uniprotkb/A0A061HYY6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A061HYY6", "url": "https://www.uniprot.org/uniprotkb/A0A061HYY6" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A061HYY6", "url": "https://www.uniprot.org/uniprotkb/A0A061HYY6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A061HYY6", "url": "https://www.uniprot.org/uniprotkb/A0A061HYY6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061HYY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HYY6" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 98, "start_aa": "Cys", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A061HYY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HYY6" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 375, "end_pos": 402, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 158 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 162, "end_pos": 164 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061HYY9-1", "uniprot_ac": "A0A061HYY9", "uniprot_id": "A0A061HYY9_CRIGR", "mass": { "chemical_mass": 50587.0, "monoisotopic_mass": 50587.0 }, "refseq": { "ac": "XP_027288782", "name": "armadillo repeat-containing X-linked protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288782" }, "gene_names": [ { "name": "Armcx1", "type": "recommended", "evidence": [ { "id": "A0A061HYY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HYY9" } ] }, { "name": "Armcx1", "type": "synonym", "evidence": [ { "id": "XP_027288782", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288782" } ] } ], "protein_names": [ { "name": "Armadillo repeat-containing X-linked protein 1", "type": "synonym", "evidence": [ { "id": "A0A061HYY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HYY9/entry#names_and_taxonomy" } ] }, { "name": "armadillo repeat-containing X-linked protein 1", "type": "synonym", "evidence": [ { "id": "XP_027288782", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288782" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027288782", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288782" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061HYY9", "url": "https://www.uniprot.org/uniprotkb/A0A061HYY9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Armcx1", "url": "https://www.uniprot.org/uniprotkb/A0A061HYY9", "locus": {} } ], "crossref": [ { "id": "100773690", "url": "https://www.ncbi.nlm.nih.gov/gene/100773690", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051303", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051303", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773690", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773690", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061HYY9", "url": "https://www.orthodb.org/?gene=A0A061HYY9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15712", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15712", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15712:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15712:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027288782", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288782", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061HYY9", "url": "https://www.uniprot.org/uniprotkb/A0A061HYY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061HYY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HYY9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRTREAGCVAAGMVIGAGACYCVYRLTWGKDENEKLWDDEEEEEEEEEESCSDKPETGGKTEKGVKTNVGVGAGPQDDSKPKADVKVGQENDPGVKIEAHPESQGEGGLEAKAKALFKILKEQASAKAGRGIRFANISGTRTLSSGLPCPGGRGGGCHPGRSGARARSRASGKAKRKNRSKITKAPATAWPVRRGKFNFPYKIDDILSAPDLQKVLNILERTNDPFTQEVALVTLGNNAAYSFNQNAIRELGGVPIIAKLIKTRDPIIREKTYNALNNLSVNSENQGKIKTYISQVCDDTMICRLDSAVQMAGLRLLTNMTVTNHYQHLLSYSFPDFFALLFLGNHFTKIQTMKLIINFTENPAMTRELVSCKVPSELISLFNKEWDREILLNILTLFENINDNIKSEGLASSRKEFSRSSLFFLFKESGVCVKKIRALANHKDLVVKVKVLKVLTKL", "length": 459, "header": "tr|A0A061HYY9-1|A0A061HYY9_CRIGR Isoform 1 of Armadillo repeat-containing X-linked protein 1 OS=Cricetulus griseus OX=10029 GN=Armcx1 PE=3 SV=1 CANONICAL=A0A061HYY9-1" }, "isoforms": [ { "isoform_ac": "A0A061HYY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HYY9/entry#A0A061HYY9-1", "sequence": { "sequence": "MGRTREAGCVAAGMVIGAGACYCVYRLTWGKDENEKLWDDEEEEEEEEEESCSDKPETGGKTEKGVKTNVGVGAGPQDDSKPKADVKVGQENDPGVKIEAHPESQGEGGLEAKAKALFKILKEQASAKAGRGIRFANISGTRTLSSGLPCPGGRGGGCHPGRSGARARSRASGKAKRKNRSKITKAPATAWPVRRGKFNFPYKIDDILSAPDLQKVLNILERTNDPFTQEVALVTLGNNAAYSFNQNAIRELGGVPIIAKLIKTRDPIIREKTYNALNNLSVNSENQGKIKTYISQVCDDTMICRLDSAVQMAGLRLLTNMTVTNHYQHLLSYSFPDFFALLFLGNHFTKIQTMKLIINFTENPAMTRELVSCKVPSELISLFNKEWDREILLNILTLFENINDNIKSEGLASSRKEFSRSSLFFLFKESGVCVKKIRALANHKDLVVKVKVLKVLTKL", "length": 459, "header": "tr|A0A061HYY9-1|A0A061HYY9_CRIGR Isoform 1 of Armadillo repeat-containing X-linked protein 1 OS=Cricetulus griseus OX=10029 GN=Armcx1 PE=3 SV=1 CANONICAL=A0A061HYY9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043374", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043374", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769500", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769500", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061HZ73", "url": "https://www.orthodb.org/?gene=A0A061HZ73", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46414", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46414", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46414:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46414:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027288757", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288757", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061HZ73", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061HZ73-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ73-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K2C3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2C3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K2C3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K2C3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTKAEMEPGAQAKAESKPGDENANTNTNGAEGESEAPMVVRPKVRTQIMPGARPKVRPKTTPAPRPRSEASAPAGAYAKCKPKSIPIARSKNDAQVWAPNRFRAEPMSKMGKQCQINPADSPLVNTDSGMVAQAKCLSVDREHGHMDTESFPRKANSQAGYQPSFGSEEGTSMGSWYRPRPTPKGEAYENSDFRWADKPSGSSSFWNRDETSARFRPRKNMKPSNTRFRHMPKQEANSMPRHKTKQELYNISSSDSEEESAKTPWFWAKEKPKVWSRPREEPNNRSWIRPKKEVRVESSSGSECENQTKSSFWSGEDAKSRPKPRARKGMNTRARHQAKREAGSDGLSASVDTNKKESCSFPEDKASALSKSKPKKEPKTRAVPKEEVKTKARATTKREARAEEEVFIGAWFWDTQEPRMVDRVSPKASLLVEEEPFVGDWFWSEEETSVDSETCCKPRRRAKEEQVRAFSLGSGKKTSMENGPKPTSKSVPVANEEEKNIVGSWFCADDEDINLEAEDESIFGSWFWGVGENSLRSVGVSYEKMLKSGEKEVTDSWFWAREVNPEAEVEEQARPASAKGTIFVPWFWSEKNLGTEPCSDIMAGAEEEPIIGPWFWAKVDNSADIDDSSKSSLEDEEEPIISPWLGAREQANMKYAAGARYKPVAEAGENNKRSDFWAKEPSLCHANRQILKSTLREQENTVDSWLWSNNYPRKQAIAGSWLWAAEEGNIDDETGEEIKLPTLEDNILNSWFWKENEETVVEAANREESKPEAEEEDIIGSWFWAGDENRFQPATEINEENKITSEEEDTVGSWLWGKEEASLEAMRRGTFESTPGIKEGKISGSWFWTEEAKVGAGSQTIETGSETEEEAIFQSLIWAAKKDNVRAGVNRVSKPENEKGPNVEVRSSAKDEVINKAGSGDNCESNAEAENIVGSWFWEGDEASFESNPTPVFKAVCKPKSSAEQEPDPSRRPQSWDEVTVQFKPGPWGKAGFPSISPFRFPKEAACLFAEMFGGKPKQEGEEESSCQSENGFPFQYDPSYRSVREIREHLKVRESADPESWSCSCIQCELNIGSEEFEELLLLMDRNRDPFIHEISKIAMGMRSASQFTRDFIRNSGVVSLIEALLNYPSTRVRTRFLEDMVSMAPPYPDLNVIQTYVCQVCEDTFDYDLDSPEQLSGLSMITHLSATSDYHKVVGKYLAGFFYLLNSGNTKTRFHVLKLLLNLSENLIMTKRLLATESMSEFMTLFSKEDSNDNIQIVLAIFDKISKNIQKEALFADDDDEEEEVVVNLDPLISAFHEIENFAKTLKRKPDN", "length": 1314, "header": "tr|A0A061HZ73-1|A0A061HZ73_CRIGR Isoform 1 of G-protein coupled receptor-associated sorting protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Gprasp1 PE=3 SV=1 CANONICAL=A0A061HZ73-1" }, "isoforms": [ { "isoform_ac": "A0A061HZ73-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ73/entry#A0A061HZ73-1", "sequence": { "sequence": "MTKAEMEPGAQAKAESKPGDENANTNTNGAEGESEAPMVVRPKVRTQIMPGARPKVRPKTTPAPRPRSEASAPAGAYAKCKPKSIPIARSKNDAQVWAPNRFRAEPMSKMGKQCQINPADSPLVNTDSGMVAQAKCLSVDREHGHMDTESFPRKANSQAGYQPSFGSEEGTSMGSWYRPRPTPKGEAYENSDFRWADKPSGSSSFWNRDETSARFRPRKNMKPSNTRFRHMPKQEANSMPRHKTKQELYNISSSDSEEESAKTPWFWAKEKPKVWSRPREEPNNRSWIRPKKEVRVESSSGSECENQTKSSFWSGEDAKSRPKPRARKGMNTRARHQAKREAGSDGLSASVDTNKKESCSFPEDKASALSKSKPKKEPKTRAVPKEEVKTKARATTKREARAEEEVFIGAWFWDTQEPRMVDRVSPKASLLVEEEPFVGDWFWSEEETSVDSETCCKPRRRAKEEQVRAFSLGSGKKTSMENGPKPTSKSVPVANEEEKNIVGSWFCADDEDINLEAEDESIFGSWFWGVGENSLRSVGVSYEKMLKSGEKEVTDSWFWAREVNPEAEVEEQARPASAKGTIFVPWFWSEKNLGTEPCSDIMAGAEEEPIIGPWFWAKVDNSADIDDSSKSSLEDEEEPIISPWLGAREQANMKYAAGARYKPVAEAGENNKRSDFWAKEPSLCHANRQILKSTLREQENTVDSWLWSNNYPRKQAIAGSWLWAAEEGNIDDETGEEIKLPTLEDNILNSWFWKENEETVVEAANREESKPEAEEEDIIGSWFWAGDENRFQPATEINEENKITSEEEDTVGSWLWGKEEASLEAMRRGTFESTPGIKEGKISGSWFWTEEAKVGAGSQTIETGSETEEEAIFQSLIWAAKKDNVRAGVNRVSKPENEKGPNVEVRSSAKDEVINKAGSGDNCESNAEAENIVGSWFWEGDEASFESNPTPVFKAVCKPKSSAEQEPDPSRRPQSWDEVTVQFKPGPWGKAGFPSISPFRFPKEAACLFAEMFGGKPKQEGEEESSCQSENGFPFQYDPSYRSVREIREHLKVRESADPESWSCSCIQCELNIGSEEFEELLLLMDRNRDPFIHEISKIAMGMRSASQFTRDFIRNSGVVSLIEALLNYPSTRVRTRFLEDMVSMAPPYPDLNVIQTYVCQVCEDTFDYDLDSPEQLSGLSMITHLSATSDYHKVVGKYLAGFFYLLNSGNTKTRFHVLKLLLNLSENLIMTKRLLATESMSEFMTLFSKEDSNDNIQIVLAIFDKISKNIQKEALFADDDDEEEEVVVNLDPLISAFHEIENFAKTLKRKPDN", "length": 1314, "header": "tr|A0A061HZ73-1|A0A061HZ73_CRIGR Isoform 1 of G-protein coupled receptor-associated sorting protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Gprasp1 PE=3 SV=1 CANONICAL=A0A061HZ73-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K2C3-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ73/entry#A0A9J7K2C3-1", "sequence": { "sequence": "MGSWYRPRPTPKGEAYENSDFRWADKPSGSSSFWNRDETSARFRPRKNMKPSNTRFRHMPKQEANSMPRHKTKQELYNISSSDSEEESAKTPWFWAKEKPKVWSRPREEPNNRSWIRPKKEVRVESSSGSECENQTKSSFWSGEDAKSRPKPRARKGMNTRARHQAKREAGSDGLSASVDTNKKESCSFPEDKASALSKSKPKKEPKTRAVPKEEVKTKARATTKREARAEEEVFIGAWFWDTQEPRMVDRVSPKASLLVEEEPFVGDWFWSEEETSVDSETCCKPRRRAKEEQVRAFSLGSGKKTSMENGPKPTSKSVPVANEEEKNIVGSWFCADDEDINLEAEDESIFGSWFWGVGENSLRSVGVSYEKMLKSGEKEVTDSWFWAREVNPEAEVEEQARPASAKGTIFVPWFWSEKNLGTEPCSDIMAGAEEEPIIGPWFWAKVDNSADIDDSSKSSLEDEEEPIISPWLGAREQANMKYAAGARYKPVAEAGENNKRSDFWAKEPSLCHANRQILKSTLREQENTVDSWLWSNNYPRKQAIAGSWLWAAEEGNIDDETGEEIKLPTLEDNILNSWFWKENEETVVEAANREESKPEAEEEDIIGSWFWAGDENRFQPATEINEENKITSEEEDTVGSWLWGKEEASLEAMRRGTFESTPGIKEGKISGSWFWTEEAKVGAGSQTIETGSETEEEAIFQSLIWAAKKDNVRAGVNRVSKPENEKGPNVEVRSSAKDEVINKAGSGDNCESNAEAENIVGSWFWEGDEASFESNPTPVFKAVCKPKSSAEQEPDPSRRPQSWDEVTVQFKPGPWGKAGFPSISPFRFPKEAACLFAEMFGGKPKQEGEEESSCQSENGFPFQYDPSYRSVREIREHLKVRESADPESWSCSCIQCELNIGSEEFEELLLLMDRNRDPFIHEISKIAMGMRSASQFTRDFIRNSGVVSLIEALLNYPSTRVRTRFLEDMVSMAPPYPDLNVIQTYVCQVCEDTFDYDLDSPEQLSGLSMITHLSATSDYHKVVGKYLAGFFYLLNSGNTKTRFHVLKLLLNLSENLIMTKRLLATESMSEFMTLFSKEDSNDNIQIVLAIFDKISKNIQKEALFADDDDEEEEVVVNLDPLISAFHEIENFAKTLKRKPDN", "length": 1142, "header": "tr|A0A9J7K2C3-1|A0A9J7K2C3_CRIGR Computationally mapped isoform of G-protein coupled receptor-associated sorting protein 1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Gprasp1 PE=3 SV=1 CANONICAL=A0A061HZ73-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 834, "start_aa": "Thr", "end_pos": 834, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr834", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061HZ73", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ73" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061HZ73", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ73" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769500", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769500", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A061HZ73", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ73" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A061HZ73", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ73" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "endosome to lysosome transport", "id": "GO:0008333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008333", "evidence": [ { "database": "UniProtKB", "id": "A0A061HZ73", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ73" } ], "pmid": "" }, { "name": "G protein-coupled receptor catabolic process", "id": "GO:1990172", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990172", "evidence": [ { "database": "UniProtKB", "id": "A0A061HZ73", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ73" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1224, "end_pos": 1226, "annotation": "n_glycosylation_sequon" }, { "start_pos": 250, "end_pos": 252, "annotation": "n_glycosylation_sequon" }, { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" }, { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061HZ73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZ73" }, { "id": "PF04826", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04826" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Armadillo repeat-containing", "eco_id": "ECO_0000259", "start_pos": 1075, "end_pos": 1281, "start_aa": "Ser", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 834 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1224, "end_pos": 1226 }, { "start_pos": 250, "end_pos": 252 }, { "start_pos": 284, "end_pos": 286 }, { "start_pos": 306, "end_pos": 308 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061HZA2-1", "uniprot_ac": "A0A061HZA2", "uniprot_id": "A0A061HZA2_CRIGR", "mass": { "chemical_mass": 11875.0, "monoisotopic_mass": 11875.0 }, "refseq": { "ac": "XP_035305826", "name": "transcription elongation factor A protein-like 7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305826" }, "gene_names": [ { "name": "Tceal7", "type": "recommended", "evidence": [ { "id": "A0A061HZA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZA2" } ] }, { "name": "Tceal7", "type": "synonym", "evidence": [ { "id": "XP_035305826", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305826" } ] } ], "protein_names": [ { "name": "Transcription elongation factor A protein-like 7", "type": "synonym", "evidence": [ { "id": "A0A061HZA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061HZA2/entry#names_and_taxonomy" } ] }, { "name": "transcription elongation factor A protein-like 7", "type": "synonym", "evidence": [ { "id": "XP_035305826", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305826" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. 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"sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061I071-1", "uniprot_ac": "A0A061I071", "uniprot_id": "A0A061I071_CRIGR", "mass": { "chemical_mass": 59767.0, "monoisotopic_mass": 59767.0 }, "refseq": { "ac": "XP_003507051", "name": "zinc finger protein OZF", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507051" }, "gene_names": [ { "name": "LOC100772364", "type": "recommended", "evidence": [ { "id": "A0A061I071", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I071" } ] }, { "name": "LOC100772364", "type": "synonym", "evidence": [ { "id": "XP_003507051", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507051" } ] } ], "protein_names": [ { "name": "Zinc finger protein OZF", "type": "synonym", "evidence": [ { "id": "A0A061I071", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I071/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein OZF", "type": "synonym", "evidence": [ { "id": "XP_003507051", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507051" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 7% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614316.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003507051", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507051" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061I071", "url": "https://www.uniprot.org/uniprotkb/A0A061I071" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100772364", "url": "https://www.uniprot.org/uniprotkb/A0A061I071", "locus": {} } ], "crossref": [ { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100772364", "url": "https://www.ncbi.nlm.nih.gov/gene/100772364", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772364", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772364", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061I071", "url": "https://www.orthodb.org/?gene=A0A061I071", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381:SF131", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381:SF131", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003507051", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507051", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061I071", "url": "https://www.uniprot.org/uniprotkb/A0A061I071", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I071-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I071-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFESRKPLKGPPTLVTMPPADGRPFAGDTWLHQKQEMEPVSFDDVVVNFTSGEWALLDSSQKKLYRDVMKETFMNLISIGRIVEENIDVDYDKLQRNLRIQVTEQFCDYEYGIQCGKPHQETPENIVNVDSYSASAVYGSSRMDVKDVNGHLSSALLIRSQTEEKPDGCQEHMEKAIKREKYWKDFTYSESFQTLESTPATENVLESKQCNESYSNLTYQRTRPGDELRGCKQFEKTLKEESYVQICEGIHTREKPFACKQCGETFIKSSHLAHHQRIHSREKTYKCRHCGETFMYSMARQNHEKTHKRERSYICKHCGKVCIHSYQLLQHERRHTREKRYTCNQCGKAFRRSSNLHKHERIHSEEKLYSCKQCGKAFISAGNCYNHERIHTAEKAYVCKQCGKAFTFSSYLRKHARIHTGEKPYACKYCGKAFTHSSAYCRHEKIHTREKPYVCVECGQAFSFSRSLQIHEKTHTAREKFHKCNQCGKEFAYFSYLQRHEKSHNEKKPSG", "length": 511, "header": "tr|A0A061I071-1|A0A061I071_CRIGR Isoform 1 of Zinc finger protein OZF OS=Cricetulus griseus OX=10029 GN=LOC100772364 PE=4 SV=1 CANONICAL=A0A061I071-1" }, "isoforms": [ { "isoform_ac": "A0A061I071-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I071/entry#A0A061I071-1", "sequence": { "sequence": "MFESRKPLKGPPTLVTMPPADGRPFAGDTWLHQKQEMEPVSFDDVVVNFTSGEWALLDSSQKKLYRDVMKETFMNLISIGRIVEENIDVDYDKLQRNLRIQVTEQFCDYEYGIQCGKPHQETPENIVNVDSYSASAVYGSSRMDVKDVNGHLSSALLIRSQTEEKPDGCQEHMEKAIKREKYWKDFTYSESFQTLESTPATENVLESKQCNESYSNLTYQRTRPGDELRGCKQFEKTLKEESYVQICEGIHTREKPFACKQCGETFIKSSHLAHHQRIHSREKTYKCRHCGETFMYSMARQNHEKTHKRERSYICKHCGKVCIHSYQLLQHERRHTREKRYTCNQCGKAFRRSSNLHKHERIHSEEKLYSCKQCGKAFISAGNCYNHERIHTAEKAYVCKQCGKAFTFSSYLRKHARIHTGEKPYACKYCGKAFTHSSAYCRHEKIHTREKPYVCVECGQAFSFSRSLQIHEKTHTAREKFHKCNQCGKEFAYFSYLQRHEKSHNEKKPSG", "length": 511, "header": "tr|A0A061I071-1|A0A061I071_CRIGR Isoform 1 of Zinc finger protein OZF OS=Cricetulus griseus OX=10029 GN=LOC100772364 PE=4 SV=1 CANONICAL=A0A061I071-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"MGSMSPDVPLLNDYKQDFLLKRFPQTVLGGPRLRLGYCAPPYIYVNQIVLFLMPWALGGTGTLLYQLDILRDYLAAALSGGLMVITASVIQLTSVYAKSKSVVVKRMIVRDILAEEDEHEFTSCTGAETVKFLIPGKKYVANTFFHSVLAGLVCGLGTWYLLPNRITLLYGSPGATAVLFVFGWITLCIGEYSLIVNTATETATFQTQDTYEITPLMRPLYILFFVSVDLAHRFIVNVPALEHMNQILHILFVFLPLLWALGTLPPPDALFFWAVEQVLEFGLGGSSMSTHLRLLVMFIISAGTPVVSYFIPSTVGVVLFMTGLGFLLSLNLSDVSLAFRHSVARHRVGSSHETFPGSFGHGFRRRDCLLCTIMLGVALLEAGLLHHYSGFSKVSGSSSQSALGYVLTALLSVLCILRETQSIYIFGIFRNPFYPKDVQAVSEFFEKQNKLLKIGVVRWILLTIVSPLAMVAFLALDSSLHGLHSVSVSIGFARAFRTVWQSTENALLETVIVSAVHVVSDTDCWWNRSLDTGTRLLLIGIMRDRLLQFITKLQFAMTVLLASWTEKKQHRKTTTTLCVLNTVFAPCVLVIIVFSALLSAPLLPLFTLPVFLVGFPRPVQSWPGAVGTSACVCTDTVFYHQMVPRLTTALQTAMAAGSLGLLLPGSHYLGRFEDRLIWIMVLERGYPYCCINVKGLELQETSCHTAEAQRVDEVFESAFQQEHLQMCSLNEHVGNILTPCTVLPVKLYSDARSVLSGIIDSHENLKEFKDDLVKVLVWVLLQYCSRRPSPQENIHKAENNREASPVALPALNTSPCPKFLEDSESLNSDTFHDWSDSSIFDDEPAIKNRKEKLQFKDLPSTNLPIPGSVDSQSEDDHSTNTASKNDLYRTVLLGFPAVDRGNREDVAYIPLVEFSCSQSHLLSLPEEWRSNCTPRSRIREASPLFPEDWYQFVLRQLECFHSKEKSGVLEEIAKDKALKALYVHTVMACYIGLFGSDNVLPSPGQIVRVYNGGLPCSGTLDWLSEKPELFQLVRKAFRYTLKLMVDKASLGPIEDFKELTSCLREYESNWYIGLVSEDQWKKAILEEKPCLFSLGYESSMGVYTSRVLVLQELLVHIGKLNSEAVRGQWANLSWELLYATNDDEERYSIQAHPLLLRNLTVQAADPPLGYPIFSSKPLSIHLC", 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061I0B2-1", "uniprot_ac": "A0A061I0B2", "uniprot_id": "A0A061I0B2_CRIGR", "mass": { "chemical_mass": 27150.0, "monoisotopic_mass": 27150.0 }, "refseq": { "ac": "XP_027279724", "name": "transmembrane protein 186", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279724" }, "gene_names": [ { "name": "Tmem186", "type": "recommended", "evidence": [ { "id": "A0A061I0B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I0B2" } ] }, { "name": "Tmem186", "type": "synonym", "evidence": [ { "id": "XP_027279724", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279724" } ] } ], "protein_names": [ { "name": "Transmembrane protein 186", "type": "recommended", "evidence": [ { "id": "A0A061I0B2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I0B2/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 186", "type": "synonym", "evidence": [ { "id": "XP_027279724", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279724" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027279724", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279724" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061I0B2", "url": "https://www.uniprot.org/uniprotkb/A0A061I0B2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tmem186", "url": "https://www.uniprot.org/uniprotkb/A0A061I0B2", "locus": {} } ], "crossref": [ { "id": "100769346", "url": "https://www.ncbi.nlm.nih.gov/gene/100769346", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769346", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769346", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061I0B2", "url": "https://www.orthodb.org/?gene=A0A061I0B2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13603", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13603", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13603:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13603:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_027279724", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279724", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061I0B2", "url": "https://www.uniprot.org/uniprotkb/A0A061I0B2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I0B2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I0B2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSSSFRGQVGLLFTAGDRIMSVFLRAVPRFQGPATWGRPLHRLWCCTGQGDSNRWVASKAPTLQEKPPGTETEKFHTIYRFRAIKRFGFLSRLKLAQTFLTVTALPPGLYWYSQGLLSVKSLYLMSGVSCFTLAMLCWMSYFFQRLVGFMYVNESGTVLRVAHLSFFGWRQDTYCAVSDIIPLSESKEHAQDLLVRIQQYGSKKTFYVTLRYGRILDRERFSQVFGNPTTLKKNN", "length": 236, "header": "tr|A0A061I0B2-1|A0A061I0B2_CRIGR Isoform 1 of Transmembrane protein 186 OS=Cricetulus griseus OX=10029 GN=Tmem186 PE=3 SV=1 CANONICAL=A0A061I0B2-1" }, "isoforms": [ { "isoform_ac": "A0A061I0B2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I0B2/entry#A0A061I0B2-1", "sequence": { "sequence": "MRSSSFRGQVGLLFTAGDRIMSVFLRAVPRFQGPATWGRPLHRLWCCTGQGDSNRWVASKAPTLQEKPPGTETEKFHTIYRFRAIKRFGFLSRLKLAQTFLTVTALPPGLYWYSQGLLSVKSLYLMSGVSCFTLAMLCWMSYFFQRLVGFMYVNESGTVLRVAHLSFFGWRQDTYCAVSDIIPLSESKEHAQDLLVRIQQYGSKKTFYVTLRYGRILDRERFSQVFGNPTTLKKNN", "length": 236, "header": "tr|A0A061I0B2-1|A0A061I0B2_CRIGR Isoform 1 of Transmembrane protein 186 OS=Cricetulus griseus OX=10029 GN=Tmem186 PE=3 SV=1 CANONICAL=A0A061I0B2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I0L8", "url": "https://www.uniprot.org/uniprotkb/A0A061I0L8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A061I0L8", "url": "https://www.uniprot.org/uniprotkb/A0A061I0L8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061I0L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I0L8" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 294, "start_aa": "Tyr", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 51, "end_pos": 53 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"https://www.uniprot.org/uniprotkb/A0A061I0R7" } ] }, { "name": "YPEL", "type": "synonym", "evidence": [ { "id": "A0A061I0R7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I0R7" } ] }, { "name": "Ypel2", "type": "synonym", "evidence": [ { "id": "XP_003503854", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503854" } ] } ], "protein_names": [ { "name": "Protein yippee-like", "type": "recommended", "evidence": [ { "id": "A0A061I0R7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I0R7/entry#names_and_taxonomy" } ] }, { "name": "protein yippee-like 2", "type": "synonym", "evidence": [ { "id": "XP_003503854", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503854" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614004.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003503854", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503854" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061I0R7", "url": "https://www.uniprot.org/uniprotkb/A0A061I0R7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ypel2", "url": "https://www.uniprot.org/uniprotkb/A0A061I0R7", "locus": {} } ], "crossref": [ { "id": "100756059", "url": "https://www.ncbi.nlm.nih.gov/gene/100756059", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756059", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756059", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SSRIYGC", "url": "https://omabrowser.org/oma/group/SSRIYGC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061I0R7", "url": "https://www.orthodb.org/?gene=A0A061I0R7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13848", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13848", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003503854", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503854", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061I0R7", "url": "https://www.uniprot.org/uniprotkb/A0A061I0R7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I0R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I0R7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVKMTRSKTFQAYLPSCHRTYSCIHCRAHLANHDELISKSFQGSQGRAYLFNSVVNVGCGPAEERVLLTGLHAVADIYCENCKTTLGWKYEHAFESSQKYKEGKYIIELAHMIKDNGWD", "length": 119, "header": "tr|A0A061I0R7-1|A0A061I0R7_CRIGR Isoform 1 of Protein yippee-like OS=Cricetulus griseus OX=10029 GN=Ypel2 PE=3 SV=1 CANONICAL=A0A061I0R7-1" }, "isoforms": [ { "isoform_ac": "A0A061I0R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I0R7/entry#A0A061I0R7-1", "sequence": { "sequence": "MVKMTRSKTFQAYLPSCHRTYSCIHCRAHLANHDELISKSFQGSQGRAYLFNSVVNVGCGPAEERVLLTGLHAVADIYCENCKTTLGWKYEHAFESSQKYKEGKYIIELAHMIKDNGWD", "length": 119, "header": "tr|A0A061I0R7-1|A0A061I0R7_CRIGR Isoform 1 of Protein yippee-like OS=Cricetulus griseus OX=10029 GN=Ypel2 PE=3 SV=1 CANONICAL=A0A061I0R7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I0R7", "url": "https://www.uniprot.org/uniprotkb/A0A061I0R7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I0R7", "url": "https://www.uniprot.org/uniprotkb/A0A061I0R7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756059", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756059", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4AAS2-1", "protein_name": "Protein yippee-like", "gene_name": "Ypel2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TAFTCVFRCFPCDPSCGSASWAAPEFAPRSAAPMVKMTRSKTFQAYLPSCHRTYSCIHCRAHLANHDELISKSFQGSQGRAYLFNSVVNVGCGPAEERVLLTGLHAVADIYCENCKTTLGWKYEHAFESSQKYKEGKYIIELAHMIKDNGWD", "length": 152 }, "evidence": [ { "id": "A0A061I0R7", "url": "https://omabrowser.org/oma/group/A0A061I0R7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F3A4-1", "protein_name": "Protein yippee-like", "gene_name": "ypel2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVTMTRSKTFQAYLPNCHRTYSCIHCRAHLANHDELISKSFQGSQGRAYLFNSVVNVGCGPAEERVLLTGLHAVADIYCENCKTTLGWKYEHAFESSQKYKEGKFIIELAHMIKDNGWD", "length": 119 }, "evidence": [ { "id": "A0A061I0R7", "url": "https://omabrowser.org/oma/group/A0A061I0R7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2YDI3-1", "protein_name": "Protein yippee-like 2", "gene_name": "YPEL2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVKMTRSKTFQAYLPSCHRTYSCIHCRAHLANHDELISKSFQGSQGRAYLFNSVVNVGCGPAEERVLLTGLHAVADIYCENCKTTLGWKYEHAFESSQKYKEGKYIIELAHMIKDNGWD", "length": 119 }, "evidence": [ { "id": "A0A061I0R7", "url": "https://omabrowser.org/oma/group/A0A061I0R7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q55FR5-1", "protein_name": "Protein yippee-like", "gene_name": "ypel", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGRLFKTYLTGPSIICCLNCKTHLTLHDQLISKQFQGRHGTAFLFGTCSNITVGPSEDRTLTTGMHIVADIYCIDCGETLGWKYEFAKEESQKYKVGKYILEKAKIQKEVNFGTQHQPHSLVALENSIM", "length": 129 }, "evidence": [ { "id": "A0A061I0R7", "url": "https://omabrowser.org/oma/group/A0A061I0R7/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q65Z95-1", "protein_name": "Protein yippee-like 2", "gene_name": "Ypel2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVKMTRSKTFQAYLPSCHRTYSCIHCRAHLANHDELISKSFQGSQGRAYLFNSVVNVGCGPAEERVLLTGLHAVADIYCENCKTTLGWKYEHAFESSQKYKEGKYIIELAHMIKDNGWD", "length": 119 }, "evidence": [ { "id": "A0A061I0R7", "url": "https://omabrowser.org/oma/group/A0A061I0R7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96QA6-1", "protein_name": "Protein yippee-like 2", "gene_name": "YPEL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVKMTRSKTFQAYLPSCHRTYSCIHCRAHLANHDELISKSFQGSQGRAYLFNSVVNVGCGPAEERVLLTGLHAVADIYCENCKTTLGWKYEHAFESSQKYKEGKYIIELAHMIKDNGWD", "length": 119 }, "evidence": [ { "id": "A0A061I0R7", "url": "https://omabrowser.org/oma/group/A0A061I0R7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W2X7-1", "protein_name": "Protein yippee-like", "gene_name": "Ypel", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVKTFQAYLPSTNRTYSCVHCRAHLASHDELISKSFQGSQGPAYLFNSVVNVACGQTEERVLLTGLHAVADIYCECCKTPLGWKYEHAYESSQKYKEGKFIIELAHMIKENGWD", "length": 114 }, "evidence": [ { "id": "A0A061I0R7", "url": "https://omabrowser.org/oma/group/A0A061I0R7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A061I0R7", "url": "https://www.uniprot.org/uniprotkb/A0A061I0R7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061I0R7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I0R7" }, { "id": "PS51792", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51792" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Yippee", "eco_id": "ECO_0000259", "start_pos": 19, "end_pos": 116, "start_aa": "Arg", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061I0S4-1", "uniprot_ac": "A0A061I0S4", "uniprot_id": "A0A061I0S4_CRIGR", "mass": { "chemical_mass": 136055.0, "monoisotopic_mass": 136055.0 }, "refseq": { "ac": "XP_027282170", "name": "integrator complex subunit 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282170" }, "gene_names": [ { "name": "Ints2", "type": "recommended", "evidence": [ { "id": "A0A061I0S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I0S4" } ] }, { "name": "Ints2", "type": "synonym", "evidence": [ { "id": "XP_027282170", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282170" } ] } ], "protein_names": [ { "name": "Integrator complex subunit 2 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A061I0S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I0S4/entry#names_and_taxonomy" } ] }, { "name": "integrator complex subunit 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027282170", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282170" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027282170", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282170" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061I0S4", "url": "https://www.uniprot.org/uniprotkb/A0A061I0S4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ints2", "url": "https://www.uniprot.org/uniprotkb/A0A061I0S4", "locus": {} } ], "crossref": [ { "id": "100774909", "url": "https://www.ncbi.nlm.nih.gov/gene/100774909", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774909", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774909", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061I0S4", "url": "https://www.orthodb.org/?gene=A0A061I0S4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JPD9", "url": "https://www.orthodb.org/?gene=A0A9J7JPD9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JYG9", "url": "https://www.orthodb.org/?gene=A0A9J7JYG9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28608", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28608", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28608:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28608:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14750", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14750", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027282170", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027282170", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061I0S4", "url": "https://www.uniprot.org/uniprotkb/A0A061I0S4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I0S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I0S4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JPD9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JPD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JPD9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JYG9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JYG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYG9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWDLDACFHFVVFNSSGSRVMMTECTSLQFVSPFAFEAMQKVDVVRLASLSDPELRLLLPCLVRMALCAPADQSQSWAQDKKLILRLLSGVEAVNSIVALLSVDFHALEQDASKEQQLRHKLGGGSGESILVSQLQHGLTLEFEHSDSPRRLRLVLSELLAIMNKVSESNGEFFFKSSELFESPVYLEEAADVLCILQAELPSLLPIVDVAEALLHVRNGAWFLCLLVANVPDSFNEVCRGLIKNGERQDEESLGGRRRTDALRFLCRMNPSQALKVRGVVVEECHLPGLGVALTLDHTKTETCEDGVSDLVCFVSGLLLGTNAKVRTWFGTFIRNGQQRKRETSGSVLWQMRRQLLLELMGILPTVRSTRIVEEADVEMEPTVSVYSGLKEEHVVKASALLRLYCALMGIAGLKPTEEEAEQLLQLMTSRPPATPAGVRFVSLSFCMLLAFSTLVSTPEQEQLMVVWLSWMIKEEAYFESTSGVSASFGEMLLLVAMYFHSNQLSAIIDLVCSTLGMKIVIKPSSLSRMKTIFTQEIFTEQVVTAHAVRVPVTSNLSANITGFLPIHCIYQLLRSRSFTKHKVSIKDWIYRQLCETSTPLHPQLLPLIDVYINSILTPASKSNPEATNQPVTEQEILNIFQEVIGGDSVRLNQRFSITAQLLVLYYILSYEEALLANTKTLASMQRKPKSYSSSLMDQIPIKFLIRQAQGLQQELGGLHSALLRLLATNYPHLCIVDDWICEEEITGTDALLRRMLLTSNAKNHSPKQLQEAFSAVPVSHTQVMQIMEHLTLLSASELIPYAEVLTSNMNQLLNSGVPRRILQTVNKLWMVLNTVMPRRLWVMTVNALQPSIKFIRQQKYTQNDLMIDPLIVLRCDRRVHRCPPLMDITLHMLNGYLLASKAYLSAHLKETAEQDRPSQNNTVGLLGQTDAPEVTREELKNALLAAQDSAAVQILLEICLPTDEEKAKGANPDISLRNTQSVITTNTPNKEMEEGEDNLLCNLREVQCLICCLLHQMYIADPNIAKLVHFQGYPCELLSLTVAGIPSMHICLDFIPELIAQPELEKQIFAIQLLSHLCIQYALPKSLSVARLAVNVMGTLLTVLTQAKRYAFFMPTLPSLVSFCRAFPPLYEDIMSLLIQIGQVCASDVATQTRDIDPVITRLQQIKEKPSGWSQICKDPSYKNGSRDTGSMDPDVQLCHCIESTIIEIINMSVSGI", "length": 1218, "header": "tr|A0A061I0S4-1|A0A061I0S4_CRIGR Isoform 1 of Integrator complex subunit 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ints2 PE=3 SV=1 CANONICAL=A0A061I0S4-1" }, "isoforms": [ { "isoform_ac": "A0A061I0S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I0S4/entry#A0A061I0S4-1", "sequence": { "sequence": "MWDLDACFHFVVFNSSGSRVMMTECTSLQFVSPFAFEAMQKVDVVRLASLSDPELRLLLPCLVRMALCAPADQSQSWAQDKKLILRLLSGVEAVNSIVALLSVDFHALEQDASKEQQLRHKLGGGSGESILVSQLQHGLTLEFEHSDSPRRLRLVLSELLAIMNKVSESNGEFFFKSSELFESPVYLEEAADVLCILQAELPSLLPIVDVAEALLHVRNGAWFLCLLVANVPDSFNEVCRGLIKNGERQDEESLGGRRRTDALRFLCRMNPSQALKVRGVVVEECHLPGLGVALTLDHTKTETCEDGVSDLVCFVSGLLLGTNAKVRTWFGTFIRNGQQRKRETSGSVLWQMRRQLLLELMGILPTVRSTRIVEEADVEMEPTVSVYSGLKEEHVVKASALLRLYCALMGIAGLKPTEEEAEQLLQLMTSRPPATPAGVRFVSLSFCMLLAFSTLVSTPEQEQLMVVWLSWMIKEEAYFESTSGVSASFGEMLLLVAMYFHSNQLSAIIDLVCSTLGMKIVIKPSSLSRMKTIFTQEIFTEQVVTAHAVRVPVTSNLSANITGFLPIHCIYQLLRSRSFTKHKVSIKDWIYRQLCETSTPLHPQLLPLIDVYINSILTPASKSNPEATNQPVTEQEILNIFQEVIGGDSVRLNQRFSITAQLLVLYYILSYEEALLANTKTLASMQRKPKSYSSSLMDQIPIKFLIRQAQGLQQELGGLHSALLRLLATNYPHLCIVDDWICEEEITGTDALLRRMLLTSNAKNHSPKQLQEAFSAVPVSHTQVMQIMEHLTLLSASELIPYAEVLTSNMNQLLNSGVPRRILQTVNKLWMVLNTVMPRRLWVMTVNALQPSIKFIRQQKYTQNDLMIDPLIVLRCDRRVHRCPPLMDITLHMLNGYLLASKAYLSAHLKETAEQDRPSQNNTVGLLGQTDAPEVTREELKNALLAAQDSAAVQILLEICLPTDEEKAKGANPDISLRNTQSVITTNTPNKEMEEGEDNLLCNLREVQCLICCLLHQMYIADPNIAKLVHFQGYPCELLSLTVAGIPSMHICLDFIPELIAQPELEKQIFAIQLLSHLCIQYALPKSLSVARLAVNVMGTLLTVLTQAKRYAFFMPTLPSLVSFCRAFPPLYEDIMSLLIQIGQVCASDVATQTRDIDPVITRLQQIKEKPSGWSQICKDPSYKNGSRDTGSMDPDVQLCHCIESTIIEIINMSVSGI", "length": 1218, "header": "tr|A0A061I0S4-1|A0A061I0S4_CRIGR Isoform 1 of Integrator complex subunit 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ints2 PE=3 SV=1 CANONICAL=A0A061I0S4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JPD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I0S4/entry#A0A9J7JPD9-1", "sequence": { "sequence": "MEVQGAGSRVMMTECTSLQFVSPFAFEAMQKVDVVRLASLSDPELRLLLPCLVRMALCAPADQSQSWAQDKKLILRLLSGVEAVNSIVALLSVDFHALEQDASKEQQLRHKLGGGSGESILVSQLQHGLTLEFEHSDSPRRLRLVLSELLAIMNKVSESNGEFFFKSSELFESPVYLEEAADVLCILQAELPSLLPIVDVAEALLHVRNGAWFLCLLVANVPDSFNEVCRGLIKNGERQDEESLGGRRRTDALRFLCRMNPSQALKVRGVVVEECHLPGLGVALTLDHTKTETCEDGVSDLVCFVSGLLLGTNAKVRTWFGTFIRNGQQRKRETSGSVLWQMRRQLLLELMGILPTVRSTRIVEEADVEMEPTVSVYSGLKEEHVVKASALLRLYCALMGIAGLKPTEEEAEQLLQLMTSRPPATPAGVRFVSLSFCMLLAFSTLVSTPEQEQLMVVWLSWMIKEEAYFESTSGVSASFGEMLLLVAMYFHSNQLSAIIDLVCSTLGMKIVIKPSSLSRMKTIFTQEIFTEQVVTAHAVRVPVTSNLSANITGFLPIHCIYQLLRSRSFTKHKVSIKDWIYRQLCETSTPLHPQLLPLIDVYINSILTPASKSNPEATNQPVTEQEILNIFQEVIGGDSVRLNQRFSITAQLLVLYYILSYEEALLANTKTLASMQRKPKSYSSSLMDQIPIKFLIRQAQGLQQELGGLHSALLRLLATNYPHLCIVDDWICEEEITGTDALLRRMLLTSNAKNHSPKQLQEAFSAVPVSHTQVMQIMEHLTLLSASELIPYAEVLTSNMNQLLNSGVPRRILQTVNKLWMVLNTVMPRRLWVMTVNALQPSIKFIRQQKYTQNDLMIDPLIVLRCDRRVHRCPPLMDITLHMLNGYLLASKAYLSAHLKETAEQDRPSQNNTVGLLGQTDAPEVTREELKNALLAAQDSAAVQILLEICLPTDEEKAKGANPDISLRNTQSVITTNTPNKEMEEGEDNLLCNLREVQCLICCLLHQMYIADPNIAKLVHFQGYPCELLSLTVAGIPSMHICLDFIPELIAQPELEKQIFAIQLLSHLCIQYALPKSLSVARLAVNVMGTLLTVLTQAKRYAFFMPTLPSLVSFCRAFPPLYEDIMSLLIQIGQVCASDVATQTRDIDPVITRLQQIKEKPSGWSQICKDPSYKNGSRDTGSMDPDVQLCHCIESTIIEIINMSVSGI", "length": 1208, "header": "tr|A0A9J7JPD9-1|A0A9J7JPD9_CRIGR Computationally mapped isoform of Integrator complex subunit 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Ints2 PE=3 SV=1 CANONICAL=A0A061I0S4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JYG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I0S4/entry#A0A9J7JYG9-1", "sequence": { "sequence": "MNGGSRVMMTECTSLQFVSPFAFEAMQKVDVVRLASLSDPELRLLLPCLVRMALCAPADQSQSWAQDKKLILRLLSGVEAVNSIVALLSVDFHALEQDASKEQQLRHKLGGGSGESILVSQLQHGLTLEFEHSDSPRRLRLVLSELLAIMNKVSESNGEFFFKSSELFESPVYLEEAADVLCILQAELPSLLPIVDVAEALLHVRNGAWFLCLLVANVPDSFNEVCRGLIKNGERQDEESLGGRRRTDALRFLCRMNPSQALKVRGVVVEECHLPGLGVALTLDHTKTETCEDGVSDLVCFVSGLLLGTNAKVRTWFGTFIRNGQQRKRETSGSVLWQMRRQLLLELMGILPTVRSTRIVEEADVEMEPTVSVYSGLKEEHVVKASALLRLYCALMGIAGLKPTEEEAEQLLQLMTSRPPATPAGVRFVSLSFCMLLAFSTLVSTPEQEQLMVVWLSWMIKEEAYFESTSGVSASFGEMLLLVAMYFHSNQLSAIIDLVCSTLGMKIVIKPSSLSRMKTIFTQEIFTEQVVTAHAVRVPVTSNLSANITGFLPIHCIYQLLRSRSFTKHKVSIKDWIYRQLCETSTPLHPQLLPLIDVYINSILTPASKSNPEATNQPVTEQEILNIFQEVIGGDSVRLNQRFSITAQLLVLYYILSYEEALLANTKTLASMQRKPKSYSSSLMDQIPIKFLIRQAQGLQQELGGLHSALLRLLATNYPHLCIVDDWICEEEITGTDALLRRMLLTSNAKNHSPKQLQEAFSAVPVSHTQVMQIMEHLTLLSASELIPYAEVLTSNMNQLLNSGVPRRILQTVNKLWMVLNTVMPRRLWVMTVNALQPSIKFIRQQKYTQNDLMIDPLIVLRCDRRVHRCPPLMDITLHMLNGYLLASKAYLSAHLKETAEQDRPSQNNTVGLLGQTDAPEVTREELKNALLAAQDSAAVQILLEICLPTDEEKAKGANPDISLRNTQSVITTNTPNKEMEEGEDNLLCNLREVQCLICCLLHQMYIADPNIAKLVHFQGYPCELLSLTVAGIPSMHICLDFIPELIAQPELEKQIFAIQLLSHLCIQYALPKSLSVARLAVNVMGTLLTVLTQAKRYAFFMPTLPSLVSFCRAFPPLYEDIMSLLIQIGQVCASDVATQTRDIDPVITRLQQIKEKPSGWSQICKDPSYKNGSRDTGSMDPDVQLCHCIESTIIEIINMSVSGI", 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This record is derived from a genomic sequence (NW_003615470.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027240349.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027240349", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240349" } ] }, { "annotation": "In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.", "evidence": [ { "database": "UniProtKB", "id": "A0A061I0V5", "url": "https://www.uniprot.org/uniprotkb/A0A061I0V5#function" }, { "database": "UniProtKB", "id": "RU368048", "url": "https://www.uniprot.org/uniprotkb/RU368048#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061I0V5", "url": "https://www.uniprot.org/uniprotkb/A0A061I0V5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ocm2", "url": "https://www.uniprot.org/uniprotkb/A0A061I0V5", "locus": {} } ], "crossref": [ { "id": "cd16255", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16255", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100768870", "url": "https://www.ncbi.nlm.nih.gov/gene/100768870", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008080", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008080", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768870", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768870", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CTCISIL", "url": "https://omabrowser.org/oma/group/CTCISIL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061I0V5", "url": "https://www.orthodb.org/?gene=A0A061I0V5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11653", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11653", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11653:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11653:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027240349", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240349", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061I0V5", "url": "https://www.uniprot.org/uniprotkb/A0A061I0V5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I0V5-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I0V5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSITDVLSADDIAAALQECQDPDTFEPQKFFQTSGLSKMSASQVKDVFRFIDNDQSGYLDEDELKFFLQKFQSDARELTESETKSLMAAADNDGDGKIGADEFQEMVHS", "length": 109, "header": "tr|A0A061I0V5-1|A0A061I0V5_CRIGR Isoform 1 of Parvalbumin OS=Cricetulus griseus OX=10029 GN=Ocm2 PE=3 SV=1 CANONICAL=A0A061I0V5-1" }, "isoforms": [ { "isoform_ac": "A0A061I0V5-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I0V5/entry#A0A061I0V5-1", "sequence": { "sequence": "MSITDVLSADDIAAALQECQDPDTFEPQKFFQTSGLSKMSASQVKDVFRFIDNDQSGYLDEDELKFFLQKFQSDARELTESETKSLMAAADNDGDGKIGADEFQEMVHS", "length": 109, "header": "tr|A0A061I0V5-1|A0A061I0V5_CRIGR Isoform 1 of Parvalbumin OS=Cricetulus griseus OX=10029 GN=Ocm2 PE=3 SV=1 CANONICAL=A0A061I0V5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I0V5", "url": "https://www.uniprot.org/uniprotkb/A0A061I0V5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615315.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003512068", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512068" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061I173", "url": "https://www.uniprot.org/uniprotkb/A0A061I173" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Bpifa3", "url": "https://www.uniprot.org/uniprotkb/A0A061I173", "locus": {} } ], "crossref": [ { "id": "100754343", "url": "https://www.ncbi.nlm.nih.gov/gene/100754343", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR017942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754343", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754343", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TNMQLDY", "url": "https://omabrowser.org/oma/group/TNMQLDY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061I173", "url": "https://www.orthodb.org/?gene=A0A061I173", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47736", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47736", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47736:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47736:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01273", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01273", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003512068", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512068", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061I173", "url": "https://www.uniprot.org/uniprotkb/A0A061I173", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I173-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I173-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHPLWRFLILLLGLLVLPSALLKEPWPGLTTAHKDGRSTLERIIAQGLLKHNAEGRIQSIRLLDRLNVSGMAAPGMVGWLIGGMNFKQQQEISINITNVQLYCDGIQMAFPKEWFSTNITLEFDVEFQLPFNSNIIKTHARMGLTAESWLEKDEFGRRELVMGRCHMEPGSEGASMSTEAVPPKMKHFLHNLRESLGKVIPNLVESQVCPLIGDILRQLDVKLLKGLVEQVAARNLGQL", "length": 239, "header": "tr|A0A061I173-1|A0A061I173_CRIGR Isoform 1 of BPI fold-containing family A member 3 OS=Cricetulus griseus OX=10029 GN=Bpifa3 PE=4 SV=1 CANONICAL=A0A061I173-1" }, "isoforms": [ { "isoform_ac": "A0A061I173-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I173/entry#A0A061I173-1", "sequence": { "sequence": "MHPLWRFLILLLGLLVLPSALLKEPWPGLTTAHKDGRSTLERIIAQGLLKHNAEGRIQSIRLLDRLNVSGMAAPGMVGWLIGGMNFKQQQEISINITNVQLYCDGIQMAFPKEWFSTNITLEFDVEFQLPFNSNIIKTHARMGLTAESWLEKDEFGRRELVMGRCHMEPGSEGASMSTEAVPPKMKHFLHNLRESLGKVIPNLVESQVCPLIGDILRQLDVKLLKGLVEQVAARNLGQL", "length": 239, "header": "tr|A0A061I173-1|A0A061I173_CRIGR Isoform 1 of BPI fold-containing family A member 3 OS=Cricetulus griseus OX=10029 GN=Bpifa3 PE=4 SV=1 CANONICAL=A0A061I173-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027289196", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027289196" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061I1F0", "url": "https://www.uniprot.org/uniprotkb/A0A061I1F0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rbmx", "url": "https://www.uniprot.org/uniprotkb/A0A061I1F0", "locus": {} } ], "crossref": [ { "id": "cd12382", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12382", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100762511", "url": "https://www.ncbi.nlm.nih.gov/gene/100762511", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003954", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003954", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762511", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762511", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061I1F0", "url": "https://www.orthodb.org/?gene=A0A061I1F0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48034", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48034", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08081", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08081", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027289196", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027289196", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061I1F0", "url": "https://www.uniprot.org/uniprotkb/A0A061I1F0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I1F0-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I1F0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K347", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K347", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K347-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K347-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGCRTSPWLPLVVGDSYRLEEKMVEADRPGKLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARDMNGKSLDGKAIKVEQATKPSFESGRRGLPPPPRSRGPPRGLRGARGGSGGTRGPPSRGGHMDDGGYSMNFTMSSSRGPLPVKRGPPPRSGGPPPKRSAPSGPVRSSSGMGGRAPVSRGRDSYGGPPRREPLPSRRDVYLSPRDDGYSTKDSYSSRDYPSSRDTRDYAPPPRDYTYRDYGHSSSRDDYPSRGYNDRDGYGRDRDYSDHPSGGSYRDSYESYGNSRSAPPTRGPPPSYGGSSRYDDYSSSRDGYGGSRDSYSSSRSDLYSSGRDRVGRQERGLPPSMERGYPPPRDSYSSSSRGAPRGGGRGGSRSDRGGGRSRY", "length": 413, "header": "tr|A0A061I1F0-1|A0A061I1F0_CRIGR Isoform 1 of RNA-binding motif protein, X chromosome isoform X2 OS=Cricetulus griseus OX=10029 GN=Rbmx PE=4 SV=1 CANONICAL=A0A061I1F0-1" }, "isoforms": [ { "isoform_ac": "A0A061I1F0-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I1F0/entry#A0A061I1F0-1", "sequence": { "sequence": "MGCRTSPWLPLVVGDSYRLEEKMVEADRPGKLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARDMNGKSLDGKAIKVEQATKPSFESGRRGLPPPPRSRGPPRGLRGARGGSGGTRGPPSRGGHMDDGGYSMNFTMSSSRGPLPVKRGPPPRSGGPPPKRSAPSGPVRSSSGMGGRAPVSRGRDSYGGPPRREPLPSRRDVYLSPRDDGYSTKDSYSSRDYPSSRDTRDYAPPPRDYTYRDYGHSSSRDDYPSRGYNDRDGYGRDRDYSDHPSGGSYRDSYESYGNSRSAPPTRGPPPSYGGSSRYDDYSSSRDGYGGSRDSYSSSRSDLYSSGRDRVGRQERGLPPSMERGYPPPRDSYSSSSRGAPRGGGRGGSRSDRGGGRSRY", "length": 413, "header": "tr|A0A061I1F0-1|A0A061I1F0_CRIGR Isoform 1 of RNA-binding motif protein, X chromosome isoform X2 OS=Cricetulus griseus OX=10029 GN=Rbmx PE=4 SV=1 CANONICAL=A0A061I1F0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K347-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I1F0/entry#A0A9J7K347-1", "sequence": { "sequence": "MVEADRPGKLFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARDMNGKSLDGKAIKVEQATKPSFESGRRGLPPPPRSRGPPRGLRGARGGSGGTRGPPSRGGHMDDGGYSMNFTMSSSRGPLPVKRGPPPRSGGPPPKRSAPSGPVRSSSGMGGRAPVSRGRDSYGGPPRREPLPSRRDVYLSPRDDGYSTKDSYSSRDYPSSRDTRDYAPPPRDYTYRDYGHSSSRDDYPSRGYNDRDGYGRDRDYSDHPSGGSYRDSYESYGNSRSAPPTRGPPPSYGGSSRYDDYSSSRDGYGGSRDSYSSSRSDLYSSGRDRVGRQERGLPPSMERGYPPPRDSYSSSSRGAPRGGGRGGSRSDRGGGRSRY", "length": 391, "header": "tr|A0A9J7K347-1|A0A9J7K347_CRIGR Computationally mapped isoform of RNA-binding motif protein, X chromosome isoform X3 OS=Cricetulus griseus OX=10029 GN=Rbmx PE=4 SV=1 CANONICAL=A0A061I1F0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I1F0", "url": "https://www.uniprot.org/uniprotkb/A0A061I1F0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I1F0", "url": "https://www.uniprot.org/uniprotkb/A0A061I1F0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762511", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762511", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A061I1F0", "url": "https://www.uniprot.org/uniprotkb/A0A061I1F0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A061I1F0", "url": "https://www.uniprot.org/uniprotkb/A0A061I1F0" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A061I1F0", "url": "https://www.uniprot.org/uniprotkb/A0A061I1F0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A061I1F0", "url": "https://www.uniprot.org/uniprotkb/A0A061I1F0" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A061I1F0", "url": "https://www.uniprot.org/uniprotkb/A0A061I1F0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 68, "end_pos": 70, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061I1F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I1F0" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 108, "start_aa": "Gly", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 159, "end_pos": 161 }, { "start_pos": 68, "end_pos": 70 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061I1F9-1", "uniprot_ac": "A0A061I1F9", "uniprot_id": "A0A061I1F9_CRIGR", "mass": { "chemical_mass": 86862.0, "monoisotopic_mass": 86862.0 }, "refseq": { "ac": "XP_003495313", "name": "ankyrin repeat and EF-hand domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495313" }, "gene_names": [ { "name": "Ankef1", "type": "recommended", "evidence": [ { "id": "A0A061I1F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I1F9" } ] }, { "name": "Ankef1", "type": "synonym", "evidence": [ { "id": "XP_003495313", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495313" } ] } ], "protein_names": [ { "name": "Ankyrin repeat and EF-hand domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A061I1F9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I1F9/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat and EF-hand domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_003495313", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495313" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613587.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003495313", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495313" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061I1F9", "url": "https://www.uniprot.org/uniprotkb/A0A061I1F9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ankef1", "url": "https://www.uniprot.org/uniprotkb/A0A061I1F9", "locus": {} } ], "crossref": [ { "id": "100750817", "url": "https://www.ncbi.nlm.nih.gov/gene/100750817", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052801", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052801", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100750817", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750817", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ATDNFMW", "url": "https://omabrowser.org/oma/group/ATDNFMW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061I1F9", "url": "https://www.orthodb.org/?gene=A0A061I1F9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24127", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24127", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24127:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24127:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003495313", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495313", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061I1F9", "url": "https://www.uniprot.org/uniprotkb/A0A061I1F9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I1F9-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I1F9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALADKRLENLQIYRVLQCVRNKDKKQIEKLTRLGYPELINFTEPIDGLSALHLASISNDIDMVSFLLGLGAHPDVQDRMGCTPTMRAAELGHELSMEILAKAKADMTIVDNEGKGILFYCILPTKRHYRCSLIALDHGADVNNITYEGKPVFLKACEEAHDVKEMCMTFLEKGANPNAINSSTGRTALMEASREGAVELVRGILERGGEVNAFDNDRHHAAHFAAKGGFFDILKLLFAYSGDMGLIGMNGNTPLHYAAMGGFADCCKYLAQRGCELKWKNLEHKTPRAVAKDGGFKAASKEIRRAERTAAKLAKPGVKNPNPIWALRLHDWSIEHEAFLREAFTFVDRGDGSVSKDDFVVTLEERQDFATPDQLLQIAQMHEKSRGSGININDFFKGTKYLSKSFVLGSFGPKKKKKSLSRKPKKGKFFLPLPVCTIPENAFPRRPDGGPPYYMIETYQNVSDCSRFNRDHPPDHPIQDDSVWYMDEPGKVFANINFITMAGDLSSLKKAFEAGIPVDMKDSSYKTPLMTACASGNLDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLIKSGAAVDAMSINNSTPLSRAIESCRLDTVKYLLDIGAKFQIENRRGHAAMDVAKAYADYRIIDMIKEKIDSLPKPLDNQKMKPKLPKLKSEGTDIKKEEETLSSVYAVPPITEEKKLSKDNVVYLNSLITSGYTKKVDITFIPRRIWSPEATTAELIRKRELRRERFTYEVDFEDFMMPFQKNIMEKAQALEASLKL", "length": 775, "header": "tr|A0A061I1F9-1|A0A061I1F9_CRIGR Isoform 1 of Ankyrin repeat and EF-hand domain-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Ankef1 PE=4 SV=1 CANONICAL=A0A061I1F9-1" }, "isoforms": [ { "isoform_ac": "A0A061I1F9-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I1F9/entry#A0A061I1F9-1", "sequence": { "sequence": "MALADKRLENLQIYRVLQCVRNKDKKQIEKLTRLGYPELINFTEPIDGLSALHLASISNDIDMVSFLLGLGAHPDVQDRMGCTPTMRAAELGHELSMEILAKAKADMTIVDNEGKGILFYCILPTKRHYRCSLIALDHGADVNNITYEGKPVFLKACEEAHDVKEMCMTFLEKGANPNAINSSTGRTALMEASREGAVELVRGILERGGEVNAFDNDRHHAAHFAAKGGFFDILKLLFAYSGDMGLIGMNGNTPLHYAAMGGFADCCKYLAQRGCELKWKNLEHKTPRAVAKDGGFKAASKEIRRAERTAAKLAKPGVKNPNPIWALRLHDWSIEHEAFLREAFTFVDRGDGSVSKDDFVVTLEERQDFATPDQLLQIAQMHEKSRGSGININDFFKGTKYLSKSFVLGSFGPKKKKKSLSRKPKKGKFFLPLPVCTIPENAFPRRPDGGPPYYMIETYQNVSDCSRFNRDHPPDHPIQDDSVWYMDEPGKVFANINFITMAGDLSSLKKAFEAGIPVDMKDSSYKTPLMTACASGNLDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLIKSGAAVDAMSINNSTPLSRAIESCRLDTVKYLLDIGAKFQIENRRGHAAMDVAKAYADYRIIDMIKEKIDSLPKPLDNQKMKPKLPKLKSEGTDIKKEEETLSSVYAVPPITEEKKLSKDNVVYLNSLITSGYTKKVDITFIPRRIWSPEATTAELIRKRELRRERFTYEVDFEDFMMPFQKNIMEKAQALEASLKL", "length": 775, "header": "tr|A0A061I1F9-1|A0A061I1F9_CRIGR Isoform 1 of Ankyrin repeat and EF-hand domain-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Ankef1 PE=4 SV=1 CANONICAL=A0A061I1F9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I1F9", "url": "https://www.uniprot.org/uniprotkb/A0A061I1F9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I1F9", "url": "https://www.uniprot.org/uniprotkb/A0A061I1F9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100750817", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750817", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Z5B9-1", "protein_name": "Ankyrin repeat and EF-hand domain containing 1", "gene_name": "ANKEF1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLPVDNRLRNLQIYKLLQCVHQKDKKQIEKLIQNGFPNLINFTEPMDGHSALSLACIKNDIDMCSFLLERGAHPDVQDKMGCTPAMKAAELGHSLVLELLAKIKADMTIVDNEGKGVLFYCILPTRRHYHCTQIALDYGADINNCSTDGKPVFLQACEQAHDIKEICLNFLERGANPNARDPVTGRTAIMEAAREGALEVVRGILERGGDINLFDNERHNAAHFAAKGGFFEILRIISAYNGDLGLIAMNGNTPLHYAAEGGFANCCKFIGQRGCDPTWTNLLAKTPRAVAKEGGFKAAATELHKIEKNFIKQSKPGAKENNPLWALRLYDWSLEHQTALLQAFEAVDQGDGTVAKDDFISVIQKWCSFVDAEQIQTIAEAHEKPDSEGINTEEFFKGFKYLQKSCLITSFGPKRKKGKKGKKRRSKKSVAVPVPICVIPKSACLLREDGFPVYMIEAVQSTADSYHINQDHPSAHPVHDDRAWYTDEPRKMYMNINFLVRAGDILSLQKAFEEGVPVDIKDKYYKTPLMAACTSGNIDVVRYLLEKGADVNATDNFMWTPLHHACYNGHLDIAELMVKAGGAIDAPAIGNATPLMRAVEICRLDIVHFLIDAGADVQTTNSNGKNALDIAKVFADSRIIDLLQNKLDNLPKVTEKKGAEKGTVAKPKMPSAPTPSEVQAVKTEPSHASLPPLEKPRLEKPAQDSVVYLNSLISSGATKKDDIAFKPRKIWTPDAATKELVRKQELLWERSTLGGDSENFESPFKRKVTE", "length": 770 }, "evidence": [ { "id": "A0A061I1F9", "url": "https://omabrowser.org/oma/group/A0A061I1F9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4A9E7-1", "protein_name": "Ankyrin repeat and EF-hand domain containing 1", "gene_name": "Ankef1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALADKRLENLQIYRVLQCVRNKDKKQIEKLTKLGYPELINFTEPIDGLSALHLASVSNDIDMVSFLLGLGAHPDVQDHMGCTPTMRAAELGHELSMEILAKAKADMTIVDNEGKGVLFYCILPTKRHFRCSQIALEHGADVNNITYEGKPVFLRACEEAHDVKDMCLTFLEKGANPNAINTSTGRTALMESSREGVLELVRGILERGGEVNTFDNDRHNAAHFAAKGGFFDILKLLFAYSGEMGLIGMDGNTPLHFAAMGGFADCCKYIAQRGCDLKWKNLEHKTPRMVAKDGGFKAASKEIRRAERTAAKLAKPGVKNPNPLWALRLHDWSIEHESSLREAFSFVDRGDGVVSKDDFVLALEERQEFATPEQLLSVAQMHEKSRGGGVNINDFFKGTKYLSKSFVLGSFGPKKKKKGLGKKPRKGKFVLPLPICTIPENAFPRRPDGGPPYYMVETYQNVTDTNRFNRDHPPEHPIQDDSEWYIDDPNRVFANINFITKAGDLASLKKAFEAGIPVDMKDNTYKTPLMTACASGNIDVVKFLLERGANVNATDNFLWTPLHFACHAGQQDIVELLVQSGAVIDASSINNSTPLSRAIESCRLDTVKYLLDNGAKFQTENRKGHAAMDIAKAYADYRIIDMIKEKLDELPKPTDNQKMKSKLPKLKTEGTDVKKEEGTLSSIYTVPAITEEKKIHRDNVVYLNSLITSGFTKKVDITFIPKRIWSPEATTAQLIRKRELRRERFTYEVDFEDFMMPFQKNITEKAQALESMLKN", "length": 775 }, "evidence": [ { "id": "A0A061I1F9", "url": "https://omabrowser.org/oma/group/A0A061I1F9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1B993-1", "protein_name": "Ankyrin repeat and EF-hand domain containing 1", "gene_name": "ANKEF1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MALADKRLENLQIYKVLQCVRNKDKKQIEKLTRLGYPELINFTDPVNGNSALHLASVSNDIDMVSFLLSLGAHPDVQDKMGCTPTMRAAELGHELSMEILAKAKADMTVVDNEGKGILFYCILPTKRHYRCALIALEHGADVNNCTCEGKPIFLRACEEAHDVKDVCLTFLEKGANPNAINTSTGRTALMEASREGVTELVRGILERGGDVNAFDNDRHHAAHFAAKGGFFDILKLLFAYNGDMGLIAMNGNTPLHYAAMGGFADCCKYIAQRGCDLKWKNLEHKTPRNLAKEGGFKAASKEIRRAEQIANKLARPGVKNPNPHLFLRLHDWSVEHETFLREAFSFVDRGDGTVTKEDFVLTLEERQDFVNSEQLAAIAQLHEKVRGGGVNINEFFKGTRYLSKSYVLGSYGPKKKKKGMAKRARVGKFVFPLPICIIPDHVFPRRSDGGPPYYMIETYKNVTDCNRFNRDHPPEHPIQDDSAWYIDDPGKVFSNINFITKAGDLASLKKAFESGIPVDMKDNYYKTPLMTACATGNIDAVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVKSGAVVDALSINNSTPLSRAIESCRLDTVKYLLDIGAKFQLENRKGHSAMDVAKAYADSRIIGLIKEKLDNLPKPAENQKPKGKPQPKAKTEGPEIKKEEETLSAIYTVPAIVEDKKMRKDNVVYLNSLITSGYTKKVDITFIPQRIWSPEATTAELIRMRELRRERLTYEVDFDDFMMPFQKHITERAQAVEASFKM", "length": 776 }, "evidence": [ { "id": "A0A061I1F9", "url": "https://omabrowser.org/oma/group/A0A061I1F9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SBK5-1", "protein_name": "Ankyrin repeat and EF-hand domain containing 1", "gene_name": "ANKEF1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALADKRLENLQIYKVLQCVRNKDKKQIEKLTRLGYPELINFTDPINGHSALHLASVSNDIDMVSFLLNLGAHPDVQDGMGCTPAMRAAELGHELSMEILAKAKADMTIVDNEGKGILFYCILPTKRHYRCTLIALEHGADVNNCTYEGKPIFLRACEEAHDVKDVCLTLLEKGANPNAINTSTGRTALMEASREGVIELVRGILERGGEVNAFDKDRHHAAHFAAKGGFFDILKLLFAYDGDMGLIAMNGNTPLHYAAMGGFADCCKYIAQRGCDLKWKNLDHKTPRALAKEGGFRAASKEIQQAERIANKLARPGAKNPNPQLYLRLHDWSVEHETFLREAFSFVDRGDGTVTKEDFVLALEERQDFVDSEQLAVIAQLHEKVRGGGVNINDFFKGTKYLSKSYVLGSFGLKRKKKGMAKRAKKGKLVLPLPICIIPDHVFPRRSDGGLPYYMIETYQNVTDCNRFNRDHPPEHPIQDDSAWYIDDPGKAFSNINFITKAGDLASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIAELLVKSGAVVDALSINNSTPLSRAIESCSLDTVKYLLDIGAKFQLENRKGHSAMDVAKAYADYRVIGLIKEKMDNLPKPAENQKPKGKPSLKVKTEGPEIKKEEERLSSIYTIPTVVQEKKMHKDNVVYLNSLITSGYTKKVDITFIPRRIWSPEATTAELIRKRELRREKFTYEVDFDEFMMPFQKNITEKAQALEAAFRT", "length": 776 }, "evidence": [ { "id": "A0A061I1F9", "url": "https://omabrowser.org/oma/group/A0A061I1F9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9D2J7-1", "protein_name": "Ankyrin repeat and EF-hand domain-containing protein 1", "gene_name": "Ankef1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALADKRLENLQIYRVLQCVRNKDKKQIEKLTRLGYPELINFTEPIDGLSALHLASISNDTDMVSFLLKLGAHPDVQDHMGCTPTMRAAELGHELSMEILAKAKADMTIVDNEGKGVLFYCILPTKRHYRCSLIALEHGADVNNITYEGKPVFLRACEEAHDVKDMCLTFLEKGANPNAINTSTGRTALMESSREGVLEIVRGILERGGEVNAYDNDRHHAAHFAAKGGFFDILKLLFAYNGDMGLIGMDGNTPLHFAAMGGFADCCKYIAQRGCDLKWKNLEHKTPRVVAKDGGFKAASKEIRRAERTAAKLAKTGAKNPNPLWALRLHDWSIEHETSLRNAFKFVDRGDGVVSKDDFVVALEERQEYATSEQLLSVAQMHEKSRGGGVNINEFFKGTKYLSKSYVLGSFGPKKKKRGLGKKPRKGKFVLPLPICTIPENAFPRRPDGGPPYYMIETYQNVSDSHRFNRDHPPEHPIQDDSEWYIDDPSRVFANISFITKAGDLASLKKAIETGIPVDMKDNTYKTPLMIACASGNIDVVKFLIEKGANVNATDNFLWTPLHFACHAGQQDIVELLVKAGASIDATSINNSTPLSRAIESCRLDTVKYLLDMGAKFQIENRKGHAAMDIAKAYADYRIIDMIKEKLDNLPKQADNQKMKGKLPKLKTEGTDVKKEEETLSSIYTVPAITEEKKVHRDSVVYLNSLITSGFTKKVDITFIPKRIWSPEATTAELIRKRELRRERFTYEVDFEDFMMPFQKNITEKAQALEATLKN", "length": 775 }, "evidence": [ { "id": "A0A061I1F9", "url": "https://omabrowser.org/oma/group/A0A061I1F9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NU02-1", "protein_name": "Ankyrin repeat and EF-hand domain-containing protein 1", "gene_name": "ANKEF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALADKRLENLQIYKVLQCVRNKDKKQIEKLTKLGYPELINYTEPINGLSALHLASVSNDIDMVSFLLDLGAHPDVQDRMGCTPTMRAAELGHELSMEILAKAKADMTIVDNEGKGVLFYCILPTKRHYRCALIALEHGADVNNSTYEGKPIFLRACEDAHDVKDVCLTFLEKGANPNAINSSTGRTALMEASREGVVEIVRGILERGGEVNAFDNDRHHAAHFAAKGGFFDILKLLFAYNGDVGLISINGNTPLHYAAMGGFADCCKYIAQRGCDLKWKNLDHKTPRAVAKEGGFKAASKEIRRAERIANKLARPGAKNPNPLWALRLHDWSVEREAFLREAFAVLDRGDGSISKNDFVMVLEERQDYASSEQLAAIAHLHEKTRGGGVNINEFFKGTRYLNKSFVLGSYGPKKKEKGMGKKGKKGKFVLPLPICVIPEYAFPRRQDGGPPYYMIETYKNVTDSSRFNRDHPPEHPIQDDSVWYIDDSEKVFSNINIITKAGDLASLKKAFESGIPVDMKDNYYKTPLMTACASGNIDVVKFLLEKGANVNATDNFLWTPLHFACHAGQQDIVELLVESGALIDAASINNSTPLNRAIESCRLDTVKYLLDIGAKFQLENRKGHSAMDVAKAYADYRIIDLIKEKLDNLPKPAENQKLKGKTPPILKTEGPEIKKEEELLSSIYGVPTTSEGKKVQKGNVVHLNSLITSGYTKKVDITFIPRRIWSPEATTAELIRKRELRRERFTHEVDFDDFMMPFQKNITEKARALEAALKT", "length": 776 }, "evidence": [ { "id": "A0A061I1F9", "url": "https://omabrowser.org/oma/group/A0A061I1F9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 461, "end_pos": 463, "annotation": "n_glycosylation_sequon" }, { "start_pos": 552, "end_pos": 554, "annotation": "n_glycosylation_sequon" }, { "start_pos": 590, "end_pos": 592, "annotation": "n_glycosylation_sequon" }, { "start_pos": 591, "end_pos": 593, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 144, "end_pos": 146 }, { "start_pos": 181, "end_pos": 183 }, { "start_pos": 41, "end_pos": 43 }, { "start_pos": 461, "end_pos": 463 }, { "start_pos": 552, "end_pos": 554 }, { "start_pos": 590, "end_pos": 592 }, { "start_pos": 591, "end_pos": 593 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061I1K8-1", "uniprot_ac": "A0A061I1K8", "uniprot_id": "A0A061I1K8_CRIGR", "mass": { "chemical_mass": 58623.0, "monoisotopic_mass": 58623.0 }, "refseq": { "ac": "XP_003511767", "name": "rho guanine nucleotide exchange factor 9 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511767" }, "gene_names": [ { "name": "Arhgef9", "type": "recommended", "evidence": [ { "id": "A0A061I1K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I1K8" } ] }, { "name": "Arhgef9", "type": "synonym", "evidence": [ { "id": "XP_003511767", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511767" } ] } ], "protein_names": [ { "name": "Rho guanine nucleotide exchange factor 9 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A061I1K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I1K8/entry#names_and_taxonomy" } ] }, { "name": "rho guanine nucleotide exchange factor 9 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003511767", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511767" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615217.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003511767", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511767" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061I1K8", "url": "https://www.uniprot.org/uniprotkb/A0A061I1K8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Arhgef9", "url": "https://www.uniprot.org/uniprotkb/A0A061I1K8", "locus": {} } ], "crossref": [ { "id": "cd00160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01224", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01224", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100768180", "url": "https://www.ncbi.nlm.nih.gov/gene/100768180", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. 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Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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"https://www.uniprot.org/uniprotkb/A0A061I259-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K108", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K108", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K108-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K108-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KC33", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KC33-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KC33-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHEEEIYCSLQWDSPPEEGSQKCLSPCKCSGTWCVVTVISCVFCVGLLATSIFLGIKFFQVSSLAMNQQERLIQQDKQLLNLTQWQRNYTLQMKNCQALQQRSPRSGSNCSPCPHNWIQNGRSCYYFFQIWEIWNRSKENCLKEGASLLQIDSKEEMDFLIQSLWKFKDGYWVGVYHDEPSRSWFWLDGSSPLSDLLPTERQLPSSQICGYLKDQSLFSDNCSSWKYFICEKNALGSCI", "length": 239, "header": "tr|A0A061I259-1|A0A061I259_CRIGR Isoform 1 of C-type lectin domain family 9 member A isoform X1 OS=Cricetulus griseus OX=10029 GN=Clec9a PE=4 SV=1 CANONICAL=A0A061I259-1" }, "isoforms": [ { "isoform_ac": "A0A061I259-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I259/entry#A0A061I259-1", "sequence": { "sequence": "MHEEEIYCSLQWDSPPEEGSQKCLSPCKCSGTWCVVTVISCVFCVGLLATSIFLGIKFFQVSSLAMNQQERLIQQDKQLLNLTQWQRNYTLQMKNCQALQQRSPRSGSNCSPCPHNWIQNGRSCYYFFQIWEIWNRSKENCLKEGASLLQIDSKEEMDFLIQSLWKFKDGYWVGVYHDEPSRSWFWLDGSSPLSDLLPTERQLPSSQICGYLKDQSLFSDNCSSWKYFICEKNALGSCI", "length": 239, "header": "tr|A0A061I259-1|A0A061I259_CRIGR Isoform 1 of C-type lectin domain family 9 member A isoform X1 OS=Cricetulus griseus OX=10029 GN=Clec9a PE=4 SV=1 CANONICAL=A0A061I259-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K108-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I259/entry#A0A9J7K108-1", "sequence": { "sequence": "MHEEEIYCSLQWDSPPEEGSQKCLSPCKCSGTWCVVTVISCVFCVGLLATSIFLGIKFFQVSSLAMNQQERLIQQDKQLLNLTQWQRNYTLQMKNCQALQQRSPRSGSNCSPCPHNWIQNGRSCYYFFQIWEIWNRSKENCLKEGASLLQIDSKEEMFANLSLWKFKDGYWVGVYHDEPSRSWFWLDGSSPLSDLLPTERQLPSSQICGYLKDQSLFSDNCSSWKYFICEKNALGSCI", "length": 238, "header": "tr|A0A9J7K108-1|A0A9J7K108_CRIGR Computationally mapped isoform of C-type lectin domain family 9 member A isoform X2 OS=Cricetulus griseus OX=10029 GN=Clec9a PE=4 SV=1 CANONICAL=A0A061I259-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KC33-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I259/entry#A0A9J7KC33-1", "sequence": { "sequence": "MHEEEIYCSLQWDSPPEEGSQKCLSPCKCSGTWCVVTVISCVFCVGLLATSIFLGIKFFQVSSLAMNQQERLIQQDKQLLNLTQWQRNYTLQMKNCQALQQRSPRSGCQQRDSYLPARSADTSKTNPSSQITAAAGNILSVRKTH", "length": 145, "header": "tr|A0A9J7KC33-1|A0A9J7KC33_CRIGR Computationally mapped isoform of C-type lectin domain family 9 member A isoform X3 OS=Cricetulus griseus OX=10029 GN=Clec9a PE=4 SV=1 CANONICAL=A0A061I259-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I259", "url": "https://www.uniprot.org/uniprotkb/A0A061I259" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I259", "url": "https://www.uniprot.org/uniprotkb/A0A061I259" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770747", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770747", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4AD02-1", "protein_name": "C-type lectin domain family 9 member A", "gene_name": "Clec9a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHEEEIYTSLQWDIPTSEASQKCPSLSKCPGTWCIVTVISCVVCVGLLAASIFLGIKFSQVSSLVMEQRERLIRQDTALLNLTEWQRNHTLQLKSCQASLQRSLRSGSNCNPCPPNWIQNGKSCYYAFDRWETWNNSKKSCLKEGDSLLQIDSKEEMEFINLSIWKLKGGYEYWVGVFQDGPSGSWFWEDGSSPLSDLLPTDRQLSASQICGYLKDHTLISDNCSNWKYFICEKKAFGSCI", "length": 241 }, "evidence": [ { "id": "A0A061I259", "url": 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This record is derived from a genomic sequence (NW_003615560.1) annotated using gene prediction method: Gnomon. 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automated computational analysis. 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This record is derived from a genomic sequence (NW_003614722.1) annotated using gene prediction method: Gnomon. 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"evidence": [ { "id": "A0A061I337", "url": "https://omabrowser.org/oma/group/A0A061I337/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9QYZ9-1", "protein_name": "Serine protease 30", "gene_name": "Prss30", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESRARCIFLLLLQILTRARGDILPSVCGHSRDAGKIVGGQDALEGQWPWQVSLWITEDGHICGGSLIHEVWVLTAAHCFRRSLNPSFYHVKVGGLTLSLLEPHSTLVAVRNIFVHPTYLWADASSGDIALVQLDTPLRPSQFTPVCLPAAQTPLTPGTVCWVTGWGATQERDMASVLQELAVPLLDSEDCEKMYHTQGSSLSGERIIQSDMLCAGYVEGQKDSCQGDSGGPLVCSINSSWTQVGITSWGIGCARPYRPGVYTRVPTYVDWIQRILAENHSDAYGYHSSASAAYQMLLPVLLAVALPGSL", "length": 310 }, "evidence": [ { "id": "A0A061I337", "url": "https://omabrowser.org/oma/group/A0A061I337/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": 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Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027270862", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270862" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061I3E7", "url": "https://www.uniprot.org/uniprotkb/A0A061I3E7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Sh2d7", "url": "https://www.uniprot.org/uniprotkb/A0A061I3E7", "locus": {} } ], "crossref": [ { "id": "cd10417", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10417", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100753703", "url": "https://www.ncbi.nlm.nih.gov/gene/100753703", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035885", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035885", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753703", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753703", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061I3E7", "url": "https://www.orthodb.org/?gene=A0A061I3E7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14388:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14388:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027270862", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270862", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061I3E7", "url": "https://www.uniprot.org/uniprotkb/A0A061I3E7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I3E7-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I3E7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGGPEQLHLAKAIGEAGDGRALAEIQELALKWFMETQAPSILQNGALPPWFHGFITRKQTEQLLRDKALGSFLVRLSDRAVGYILSYRGSDRCRHFVINQLRNRRYLVSGDTLSHSTLDELLRHYQEVQLEPFGETLAAACPRLEENDLYDAVNTGFQQTNMENPAAMEFPTVVADKTTSPRLPAKPQVSFLHTKKDLDVNSWTLLKEENVEAHIRVPPIPQRSPSFLDEPSAGPNDIIYADLKKMNLAQQGLGTDMCGRHRLPPAGCLACSPGRKSSKKLSDEDQSNPNSPEPAPSGVKTDQNATMPYASLGFSLPPNSEAVGSQPTTWRQGFLKLSHEAQSSSEASSVDTYQLVGTAGLLQEGRDRPDQEGSTYEQIPPCWHGTAKLPYPGVSPTYSQLSGPMDCGHEKILGTSQLPEPGNTYEQIPASKNKDTGRVNKPDKFRRFFFTDKRHKF", "length": 458, "header": "tr|A0A061I3E7-1|A0A061I3E7_CRIGR Isoform 1 of SH2 domain-containing protein 7 OS=Cricetulus griseus OX=10029 GN=Sh2d7 PE=4 SV=1 CANONICAL=A0A061I3E7-1" }, "isoforms": [ { "isoform_ac": "A0A061I3E7-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I3E7/entry#A0A061I3E7-1", "sequence": { "sequence": "MEGGPEQLHLAKAIGEAGDGRALAEIQELALKWFMETQAPSILQNGALPPWFHGFITRKQTEQLLRDKALGSFLVRLSDRAVGYILSYRGSDRCRHFVINQLRNRRYLVSGDTLSHSTLDELLRHYQEVQLEPFGETLAAACPRLEENDLYDAVNTGFQQTNMENPAAMEFPTVVADKTTSPRLPAKPQVSFLHTKKDLDVNSWTLLKEENVEAHIRVPPIPQRSPSFLDEPSAGPNDIIYADLKKMNLAQQGLGTDMCGRHRLPPAGCLACSPGRKSSKKLSDEDQSNPNSPEPAPSGVKTDQNATMPYASLGFSLPPNSEAVGSQPTTWRQGFLKLSHEAQSSSEASSVDTYQLVGTAGLLQEGRDRPDQEGSTYEQIPPCWHGTAKLPYPGVSPTYSQLSGPMDCGHEKILGTSQLPEPGNTYEQIPASKNKDTGRVNKPDKFRRFFFTDKRHKF", "length": 458, "header": "tr|A0A061I3E7-1|A0A061I3E7_CRIGR Isoform 1 of SH2 domain-containing protein 7 OS=Cricetulus griseus OX=10029 GN=Sh2d7 PE=4 SV=1 CANONICAL=A0A061I3E7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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analysis. This record is derived from a genomic sequence (NW_003617918.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007605773", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007605773" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061I3H2", "url": "https://www.uniprot.org/uniprotkb/A0A061I3H2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Eapp", "url": "https://www.uniprot.org/uniprotkb/A0A061I3H2", "locus": {} } ], "crossref": [ { "id": "100763566", "url": "https://www.ncbi.nlm.nih.gov/gene/100763566", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763566", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763566", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CFVNKEE", "url": "https://omabrowser.org/oma/group/CFVNKEE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061I3H2", "url": "https://www.orthodb.org/?gene=A0A061I3H2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15967", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15967", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15967:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15967:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10238", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10238", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007605773", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007605773", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061I3H2", "url": "https://www.uniprot.org/uniprotkb/A0A061I3H2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I3H2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I3H2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNRLQDDYDPYAVEEPSDEEPALSSSEDEVDVLLHGTPDQKRKLIRECLTGESESSSEDEFEKEMEAELNSTIKTMEDKLSSMGTGGSSAVGNVGGVTAKYYDDIYFDSDSEDEDKAAQVTKKKKKKQRRIPTNDELLYDPEKDNRDQAWVDAQRRGYHAFGLQRPHQKQQPVPNSDAVLNCPACMTTLCLDCQRHESYKTQYRAMFVMNCSVNREEVLRYKNPENRKKKRGAKKMRSNAEGPVETEEEEIYHPVMCTECSTEVAVYDKDEVFHFFNVLASHS", "length": 283, "header": "tr|A0A061I3H2-1|A0A061I3H2_CRIGR Isoform 1 of E2F-associated phosphoprotein OS=Cricetulus griseus OX=10029 GN=Eapp PE=4 SV=1 CANONICAL=A0A061I3H2-1" }, "isoforms": [ { "isoform_ac": "A0A061I3H2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I3H2/entry#A0A061I3H2-1", "sequence": { "sequence": "MNRLQDDYDPYAVEEPSDEEPALSSSEDEVDVLLHGTPDQKRKLIRECLTGESESSSEDEFEKEMEAELNSTIKTMEDKLSSMGTGGSSAVGNVGGVTAKYYDDIYFDSDSEDEDKAAQVTKKKKKKQRRIPTNDELLYDPEKDNRDQAWVDAQRRGYHAFGLQRPHQKQQPVPNSDAVLNCPACMTTLCLDCQRHESYKTQYRAMFVMNCSVNREEVLRYKNPENRKKKRGAKKMRSNAEGPVETEEEEIYHPVMCTECSTEVAVYDKDEVFHFFNVLASHS", "length": 283, "header": "tr|A0A061I3H2-1|A0A061I3H2_CRIGR Isoform 1 of E2F-associated phosphoprotein OS=Cricetulus griseus OX=10029 GN=Eapp PE=4 SV=1 CANONICAL=A0A061I3H2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I3H2", "url": "https://www.uniprot.org/uniprotkb/A0A061I3H2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I3H2", "url": "https://www.uniprot.org/uniprotkb/A0A061I3H2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763566", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763566", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XJI1-1", "protein_name": "E2F associated phosphoprotein", "gene_name": "EAPP", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSRLREEDDPYVVEEPSDEERALSSSEDEVDVLLHGTPDQKRKLLRECLTGESESSSDDEFQKEMEAELNTTVRNIEGKWKSPEMGTSSSTGEAGSATTSKYYDDVYFDSDSEDEDKTVMQDVQKKRKHQQRRILTNDELLYDPEEDSRDQEWVDSQRRRYRNQRRVLQPQQTKPSSVPNSDAVLNCPACMTTLCLDCQRHESYKTQYRAMFVMNCFVNKEEILKYRKKVKKRNKKRKHSEETTPAQSNQEEEEVYHPVLCTECSTEVAVMDKDEVFHFFNVLASHS", "length": 287 }, "evidence": [ { "id": "A0A061I3H2", "url": "https://omabrowser.org/oma/group/A0A061I3H2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "B5DF09-1", "protein_name": "E2F-associated phosphoprotein", "gene_name": "Eapp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNRLQDDYDPYAVEEPSDEEPALSSSEDEVDVLLHGTPDQKRKLIRECLTGESESSEDEFEKEMEAELNSTMKTVEDKLSSLGTGSSSGVAKVGGVTTKYYDAVYFDSDSEDEDKAVTKKKKKKQHRIPTNDELLYDPEKDSRDQAWVDAKRRGYHAFGLQRPCQKQQPVPNSDAVLNCPACMTTLCLDCQRHESYKTQYRAMFVMNCSINREEVLRYKNSDNRKKRRSAKKMRSNPEDLAEREVEEIYHPVMCTECSTEVAVYDKDEVFHFFNVLASHS", "length": 280 }, "evidence": [ { "id": "A0A061I3H2", "url": "https://omabrowser.org/oma/group/A0A061I3H2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SHH4-1", "protein_name": "E2F associated phosphoprotein", "gene_name": "EAPP", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNRLQGDYDPYAVEEPSDEEPALSSSEDEVDVLLHGTPDQKRKLIRECLTGESESSSEDEFEKEMEAELNSTLKTMEDKLSSLETGSSSGHGKVGTAPTKYYDDIYFDSDSEDEDKAAQGTKKKKKKQHRIPTNDELLYDPEKDNRDQAWVDAQRRGYHGFGIQRPRQQQQPVPNSDAVLNCPACMTTLCLDCQRHESYKTQYRAMFVMNCSVNKEEILRYKTPENRKKRRGHKKMKSNHEDAAEQAETNVEEIYHPVMCTECSTEVAVYDKDEVFHFFNVLASHS", "length": 286 }, "evidence": [ { "id": "A0A061I3H2", "url": "https://omabrowser.org/oma/group/A0A061I3H2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q56P03-1", "protein_name": "E2F-associated phosphoprotein", "gene_name": "EAPP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNRLPDDYDPYAVEEPSDEEPALSSSEDEVDVLLHGTPDQKRKLIRECLTGESESSSEDEFEKEMEAELNSTMKTMEDKLSSLGTGSSSGNGKVATAPTRYYDDIYFDSDSEDEDRAVQVTKKKKKKQHKIPTNDELLYDPEKDNRDQAWVDAQRRGYHGLGPQRSRQQQPVPNSDAVLNCPACMTTLCLDCQRHESYKTQYRAMFVMNCSINKEEVLRYKASENRKKRRVHKKMRSNREDAAEKAETDVEEIYHPVMCTECSTEVAVYDKDEVFHFFNVLASHS", "length": 285 }, "evidence": [ { "id": "A0A061I3H2", "url": "https://omabrowser.org/oma/group/A0A061I3H2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5BU09-1", "protein_name": "E2F-associated phosphoprotein", "gene_name": "Eapp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNRLQDDYDPYAVEEPSDEEPALSSSEDELDVLLHGTPDQKRKLIRECLTGESESSSEDEFEKEMEAELNSTMKTMEDQLSSLGTGSSSGVAKVGGVTEKFYDEIYFDSDSEDEDKTVTKKKKKKQHRIPTNDELLYDPEKDNRDQAWVDAKRRGYHAFGLQRPRQKQQPVPNSDAVLNCPACMTTLCLDCQRHESYKTQYRAMFVMNCSINREEVLRYKNPENRRKRRSAKKMRSNPEDPAEREAEEIYHPVMCTECSTEVAVYDKDEVFHFFNVLASHS", "length": 281 }, "evidence": [ { "id": "A0A061I3H2", "url": "https://omabrowser.org/oma/group/A0A061I3H2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "A0A061I3H2", "url": "https://www.uniprot.org/uniprotkb/A0A061I3H2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 210, "end_pos": 212 }, { "start_pos": 70, "end_pos": 72 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061I3K4-1", "uniprot_ac": "A0A061I3K4", "uniprot_id": "A0A061I3K4_CRIGR", "mass": { "chemical_mass": 61336.0, "monoisotopic_mass": 61336.0 }, "refseq": { "ac": "XP_003504760", "name": "zinc finger protein OZF", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504760" }, "gene_names": [ { "name": "LOC100774889", "type": "recommended", "evidence": [ { "id": "A0A061I3K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I3K4" } ] }, { "name": "LOC100774889", "type": "synonym", "evidence": [ { "id": "XP_003504760", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504760" } ] } ], "protein_names": [ { "name": "Zinc finger protein OZF", "type": "synonym", "evidence": [ { "id": "A0A061I3K4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I3K4/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein OZF", "type": "synonym", "evidence": [ { "id": "XP_003504760", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504760" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614083.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003504760", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504760" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A061I3K4", "url": "https://www.uniprot.org/uniprotkb/A0A061I3K4#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061I3K4", "url": "https://www.uniprot.org/uniprotkb/A0A061I3K4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100774889", "url": "https://www.uniprot.org/uniprotkb/A0A061I3K4", "locus": {} } ], "crossref": [ { "id": "cd07765", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07765", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100774889", "url": "https://www.ncbi.nlm.nih.gov/gene/100774889", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774889", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774889", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061I3K4", "url": "https://www.orthodb.org/?gene=A0A061I3K4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384:SF247", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384:SF247", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01352", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01352", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003504760", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504760", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061I3K4", "url": "https://www.uniprot.org/uniprotkb/A0A061I3K4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I3K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I3K4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPVTFEDVAVNFTLGEWTMLDSSQKKLYRDVMKETFLNLISIGKTEEEDTEEEYQKPKGNLRTLVVERLCKFDHGGQSGETHRQSPEHVVNEKMPPAITEWERDMIAHLPSDTCVRGQTGEKPYQYQEHMEKAFKYKKCWKDFSYSELLWMHKSPPMKQKLHENKQSNEVCRSFTSDHDYEGTYTEEKSYVCKQCGKAWSDSCSLLWHEKSHIQEKRHTCKQCGKAFSRPSQLHKHERIHTGEKPYVCTHCGKAFIDRRTCYNHERTHTGVKPYACKQCGKAFLRSCQLLIHERIHTGERPFVCKHCGKAFTYSSACYYHERIHTGEKPCVCKQCGKAFKCSAYLHIHERSHSGEKPYVCKHCGKAFAYATGCHKHERIHSGEKPYMCVQCGKLFSFPRSLHIHERSHSGEKPYVCKQCGKSFSQGTSLKRHERIHTGEKPYVCRQCGKAFIQRDDCYSHERTHTGEKPYMCVQCGKTFTFSKSLQIHEKNHTGEKPYICKQCGKAFTCSTYLLRHERTHSEKLSG", "length": 527, "header": "tr|A0A061I3K4-1|A0A061I3K4_CRIGR Isoform 1 of Zinc finger protein OZF OS=Cricetulus griseus OX=10029 GN=LOC100774889 PE=3 SV=1 CANONICAL=A0A061I3K4-1" }, "isoforms": [ { "isoform_ac": "A0A061I3K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I3K4/entry#A0A061I3K4-1", "sequence": { "sequence": 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"id": "A0A061I3R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I3R0/entry#names_and_taxonomy" } ] }, { "name": "zinc finger CW-type PWWP domain protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_016835257", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016835257" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 290 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614921.1) and transcript sequence (IACG01033089.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016835257", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016835257" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061I3R0", "url": "https://www.uniprot.org/uniprotkb/A0A061I3R0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Zcwpw1", "url": "https://www.uniprot.org/uniprotkb/A0A061I3R0", "locus": {} } ], "crossref": [ { "id": "cd20145", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20145", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100754258", "url": "https://www.ncbi.nlm.nih.gov/gene/100754258", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011124", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011124", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042778", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042778", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754258", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754258", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CAQPIRC", "url": "https://omabrowser.org/oma/group/CAQPIRC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061I3R0", "url": "https://www.orthodb.org/?gene=A0A061I3R0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A061I508", "url": "https://www.orthodb.org/?gene=A0A061I508", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A061I7F1", "url": "https://www.orthodb.org/?gene=A0A061I7F1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A061IAG0", "url": "https://www.orthodb.org/?gene=A0A061IAG0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G1E6", "url": "https://www.orthodb.org/?gene=A0A9J7G1E6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G3S8", "url": "https://www.orthodb.org/?gene=A0A9J7G3S8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JNC2", "url": "https://www.orthodb.org/?gene=A0A9J7JNC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15999", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15999", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15999:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15999:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07496", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07496", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016835257", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016835257", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061I3R0", "url": "https://www.uniprot.org/uniprotkb/A0A061I3R0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I3R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I3R0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I508", "url": "https://www.uniprot.org/uniprotkb/A0A061I508", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I508-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I508-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I7F1", "url": "https://www.uniprot.org/uniprotkb/A0A061I7F1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I7F1-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I7F1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IAG0", "url": "https://www.uniprot.org/uniprotkb/A0A061IAG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IAG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IAG0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1E6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1E6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G1E6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G1E6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3S8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3S8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3S8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3S8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JNC2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JNC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JNC2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMATSQNIKEYEKGTKKTFASPTQKSHHVKPQADSWKEDPQGTSSLEAEAKPRRPRASPKKEQKTATEHGPNGGQEKKRKAQDKPAKKKGKEKQTLTNAEFEEIFQIVLRKSLQEYLGLGSGLNFAETSCVQPIIPTKSDKEPGIASPATDNENADGINSREEVIVPDTREIASSLEEEVDSEIRTSKPGQLAAEPSKKKSNRLSLSKRRKKSEDEKMEEIQDGYECILKDKQKTTIQDPSQIRGQQKEEEGGFGQCLIWVQCSSSKCEKWRQLRGDIDPSVLPDNWSCDQNPDLNYNRCDIPEETWTGCESDVAYASYVPGSIVWAKQYGYPWWPGMIETDPDLGEYFLFSSHLDSLPSKYHVTYFGERVSRAWIPVSMLKNFQELSLELVRGKTCRNKDYNQKLEAAIAMAHKAEQINIQERVNLFGFRSRYSGSDSSGEGKDLMLRESSSPESCLQKEKDSGEEEKEEKEDPTLPKPKPAKIQTKKIKSRGPAGGQGGRPKEKTVKKSLSSESTIPLAPVLGGKEEQGNSELGHPGPKKKFKAPESKASATTLPEKQEIKIVSKCPTPPAGHGVCRLGKEGPGPQEPLTQEAAIFPLEDDGSSDLDLEQLMEDIGETEERGESQQRDGSEGFLAALFEE", "length": 642, "header": "tr|A0A061I3R0-1|A0A061I3R0_CRIGR Isoform 1 of Zinc finger CW-type PWWP domain protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Zcwpw1 PE=4 SV=1 CANONICAL=A0A061I3R0-1" }, "isoforms": [ { "isoform_ac": "A0A061I3R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I3R0/entry#A0A061I3R0-1", "sequence": { "sequence": "MMATSQNIKEYEKGTKKTFASPTQKSHHVKPQADSWKEDPQGTSSLEAEAKPRRPRASPKKEQKTATEHGPNGGQEKKRKAQDKPAKKKGKEKQTLTNAEFEEIFQIVLRKSLQEYLGLGSGLNFAETSCVQPIIPTKSDKEPGIASPATDNENADGINSREEVIVPDTREIASSLEEEVDSEIRTSKPGQLAAEPSKKKSNRLSLSKRRKKSEDEKMEEIQDGYECILKDKQKTTIQDPSQIRGQQKEEEGGFGQCLIWVQCSSSKCEKWRQLRGDIDPSVLPDNWSCDQNPDLNYNRCDIPEETWTGCESDVAYASYVPGSIVWAKQYGYPWWPGMIETDPDLGEYFLFSSHLDSLPSKYHVTYFGERVSRAWIPVSMLKNFQELSLELVRGKTCRNKDYNQKLEAAIAMAHKAEQINIQERVNLFGFRSRYSGSDSSGEGKDLMLRESSSPESCLQKEKDSGEEEKEEKEDPTLPKPKPAKIQTKKIKSRGPAGGQGGRPKEKTVKKSLSSESTIPLAPVLGGKEEQGNSELGHPGPKKKFKAPESKASATTLPEKQEIKIVSKCPTPPAGHGVCRLGKEGPGPQEPLTQEAAIFPLEDDGSSDLDLEQLMEDIGETEERGESQQRDGSEGFLAALFEE", "length": 642, "header": "tr|A0A061I3R0-1|A0A061I3R0_CRIGR Isoform 1 of Zinc finger CW-type PWWP domain protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Zcwpw1 PE=4 SV=1 CANONICAL=A0A061I3R0-1" }, "locus": {} }, { "isoform_ac": "A0A061I508-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I3R0/entry#A0A061I508-1", "sequence": { "sequence": "MMATSQNIKEYEKGTKKTFASPTQKSHHVKPQADSWKEDPQGTSSLEAEAKPRRPRASPKKEQKTATEHGPNGGQEKKRKAQDKPAKKKGKEKQTLTNAEFEEIFQIVLRKSLQEYLETSCVQPIIPTKSDKEPGIASPATDNENADGINSREEVIVPDTREIASSLEEEVDSEIRTSKPGQLAAEPSKKKSNRLSLSKRRKKSEDEKMEEIQDGYECILKDKQKTTIQDPSQIRGQQKEEEGGFGQCLIWVQCSSSKCEKWRQLRGDIDPSVLPDNWSCDQNPDLNYNRCDIPEETWTGCESDVAYASYVPGSIVWAKQYGYPWWPGMIETDPDLGEYFLFSSHLDSLPSKYHVTYFGERVSRAWIPVSMLKNFQELSLELVRGKTCRNKDYNQKLEAAIAMAHKAEQINIQERVNLFGFRSRYSGSDSSGEGKDLMLRESSSPESCLQKEKDSGEEEKEEKEDPTLPKPKPAKIQTKKIKSRGPAGGQGGRPKEKTVKKSLSSESTIPLAPVLGGKEEQGNSELGHPGPKKKFKAPESKASATTLPEKQEIKIVSKCPTPPAGHGVCRLGKEGPGPQEPLTQEAAIFPLEDDGSSDLDLEQLMEDIGETEERGESQQRDGSEGFLAALFEE", "length": 633, "header": "tr|A0A061I508-1|A0A061I508_CRIGR Computationally mapped isoform of Zinc finger CW-type PWWP domain protein 1 isoform X5 OS=Cricetulus griseus OX=10029 GN=Zcwpw1 PE=4 SV=1 CANONICAL=A0A061I3R0-1" }, "locus": {} }, { "isoform_ac": "A0A061I7F1-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I3R0/entry#A0A061I7F1-1", "sequence": { "sequence": "MMATSQNIKEYEKGTKKTFASPTQKSHHVKPQADSWKEDPQGTSSLEAEAKPRRPRASPKKEQKTATEHGPNGGQEKKRKAQDKPAKKKGKEKQTLTNAEFEEIFQIVLRKSLQEYLGLGSGLNFAETSCVQPIIPTKSDKEPGIASPATDNENADGINSREEVIVPDTREIASSLEEEVDSEIRTSKPGQLAAEPSKKKSNRLSLSKRRKKSEDEKMEEIQDGYECILKDKQKTTIQDPSQIRGQQKEEEGGFGQCLIWVQCSSSKCEKWRQLRGDIDPSVLPDNWSCDQNPDLNYNRCDIPEETWTGCESDVAYASYVPGSIVWAKQYGYPWWPGMIETDPDLGEYFLFSSHLDSLPKTCRNKDYNQKLEAAIAMAHKAEQINIQERVNLFGFRSRYSGSDSSGEGKDLMLRESSSPESCLQKEKDSGEEEKEEKEDPTLPKPKPAKIQTKKIKSRGPAGGQGGRPKEKTVKKSLSSESTIPLAPVLGGKEEQGNSELGHPGPKKKFKAPESKASATTLPEKQEIKIVSKCPTPPAGHGVCRLGKEGPGPQEPLTQEAAIFPLEDDGSSDLDLEQLMEDIGETEERGESQQRDGSEGFLAALFEE", "length": 607, "header": "tr|A0A061I7F1-1|A0A061I7F1_CRIGR Computationally mapped isoform of Zinc finger CW-type PWWP domain protein 1 isoform X7 OS=Cricetulus griseus OX=10029 GN=Zcwpw1 PE=4 SV=1 CANONICAL=A0A061I3R0-1" }, "locus": {} }, { "isoform_ac": "A0A061IAG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I3R0/entry#A0A061IAG0-1", "sequence": { "sequence": "MMATSQNIKEYEKGTKKTFASPTQKSHHVKPQADSWKEDPQGTSSLEAEAKPRRPRASPKKEQKTATEHGPNGGQEKKRKAQDKPAKKKGKEKQTLTNAEFEEIFQIVLRKSLQEYLGLGSGLNFAETSCVQPIIPTKSDKEPGIASPATDNENADGEEVIVPDTREIASSLEEEVDSEIRTSKPGQLAAEPSKKKSNRLSLSKRRKKSEDEKMEEIQDGYECILKDKQKTTIQDPSQIRGQQKEEEGGFGQCLIWVQCSSSKCEKWRQLRGDIDPSVLPDNWSCDQNPDLNYNRCDIPEETWTGCESDVAYASYVPGSIVWAKQYGYPWWPGMIETDPDLGEYFLFSSHLDSLPSKYHVTYFGERVSRAWIPVSMLKNFQELSLELVRGKTCRNKDYNQKLEAAIAMAHKAEQINIQERVNLFGFRSRYSGSDSSGEGKDLMLRESSSPESCLQKEKDSGEEEKEEKEDPTLPKPKPAKIQTKKIKSRGPAGGQGGRPKEKTVKKSLSSESTIPLAPVLGGKEEQGNSELGHPGPKKKFKAPESKASATTLPEKQEIKIVSKCPTPPAGHGVCRLGKEGPGPQEPLTQEAAIFPLEDDGSSDLDLEQLMEDIGETEERGESQQRDGSEGFLAALFEE", "length": 638, "header": "tr|A0A061IAG0-1|A0A061IAG0_CRIGR Computationally mapped isoform of Zinc finger CW-type PWWP domain protein 1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Zcwpw1 PE=4 SV=1 CANONICAL=A0A061I3R0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G1E6-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I3R0/entry#A0A9J7G1E6-1", "sequence": { "sequence": "MMATSQNIKEYEKGTKKTFASPTQKSHHVKPQADSWKEDPQGTSSLEAEAKPRRPRASPKKEQKTATEHGPNGGQEKKRKAQDKPAKKKGKEKQTLTNAEFEEIFQIVLRKSLQEYLGLGSGLNFAETSCVQPIIPTKSDKEPGIASPATDNENADGINSREEVIVPDTREIASSLEEEVDSEIRTSKPGQLAAEPSKKKSNRLSLSKRRKKSDEKMEEIQDGYECILKDKQKTTIQDPSQIRGQQKEEEGGFGQCLIWVQCSSSKCEKWRQLRGDIDPSVLPDNWSCDQNPDLNYNRCDIPEETWTGCESDVAYASYVPGSIVWAKQYGYPWWPGMIETDPDLGEYFLFSSHLDSLPSKYHVTYFGERVSRAWIPVSMLKNFQELSLELVRGKTCRNKDYNQKLEAAIAMAHKAEQINIQERVNLFGFRSRYSGSDSSGEGKDLMLRESSSPESCLQKEKDSGEEEKEEKEDPTLPKPKPAKIQTKKIKSRGPAGGQGGRPKEKTVKKSLSSESTIPLAPVLGGKEEQGNSELGHPGPKKKFKAPESKASATTLPEKQEIKIVSKCPTPPAGHGVCRLGKEGPGPQEPLTQEAAIFPLEDDGSSDLDLEQLMEDIGETEERGESQQRDGSEGFLAALFEE", "length": 641, "header": "tr|A0A9J7G1E6-1|A0A9J7G1E6_CRIGR Computationally mapped isoform of Zinc finger CW-type PWWP domain protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Zcwpw1 PE=4 SV=1 CANONICAL=A0A061I3R0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G3S8-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I3R0/entry#A0A9J7G3S8-1", "sequence": { "sequence": "MMATSQNIKEYEKGTKKTFASPTQKSHHVKPQADSWKEDPQGTSSLEAEAKPRRPRASPKKEQKTATEHGPNGGQEKKRKAQDKPAKKKGKEKQTLTNAEFEEIFQIVLRKSLQEYLGLGSGLNFAETSCVQPIIPTKSDKEPGIASPATDNENADGEEVIVPDTREIASSLEEEVDSEIRTSKPGQLAAEPSKKKSNRLSLSKRRKKSDEKMEEIQDGYECILKDKQKTTIQDPSQIRGQQKEEEGGFGQCLIWVQCSSSKCEKWRQLRGDIDPSVLPDNWSCDQNPDLNYNRCDIPEETWTGCESDVAYASYVPGSIVWAKQYGYPWWPGMIETDPDLGEYFLFSSHLDSLPSKYHVTYFGERVSRAWIPVSMLKNFQELSLELVRGKTCRNKDYNQKLEAAIAMAHKAEQINIQERVNLFGFRSRYSGSDSSGEGKDLMLRESSSPESCLQKEKDSGEEEKEEKEDPTLPKPKPAKIQTKKIKSRGPAGGQGGRPKEKTVKKSLSSESTIPLAPVLGGKEEQGNSELGHPGPKKKFKAPESKASATTLPEKQEIKIVSKCPTPPAGHGVCRLGKEGPGPQEPLTQEAAIFPLEDDGSSDLDLEQLMEDIGETEERGESQQRDGSEGFLAALFEE", "length": 637, "header": "tr|A0A9J7G3S8-1|A0A9J7G3S8_CRIGR Computationally mapped isoform of Zinc finger CW-type PWWP domain protein 1 isoform X4 OS=Cricetulus griseus OX=10029 GN=Zcwpw1 PE=4 SV=1 CANONICAL=A0A061I3R0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JNC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I3R0/entry#A0A9J7JNC2-1", "sequence": { "sequence": "MMATSQNIKEYEKGTKKTFASPTQKSHHVKPQADSWKEDPQGTSSLEAEAKPRRPRASPKKEQKTATEHGPNGGQEKKRKAQDKPAKKKGKEKQTLTNAEFEEIFQIVLRKSLQEYLETSCVQPIIPTKSDKEPGIASPATDNENADGEEVIVPDTREIASSLEEEVDSEIRTSKPGQLAAEPSKKKSNRLSLSKRRKKSEDEKMEEIQDGYECILKDKQKTTIQDPSQIRGQQKEEEGGFGQCLIWVQCSSSKCEKWRQLRGDIDPSVLPDNWSCDQNPDLNYNRCDIPEETWTGCESDVAYASYVPGSIVWAKQYGYPWWPGMIETDPDLGEYFLFSSHLDSLPSKYHVTYFGERVSRAWIPVSMLKNFQELSLELVRGKTCRNKDYNQKLEAAIAMAHKAEQINIQERVNLFGFRSRYSGSDSSGEGKDLMLRESSSPESCLQKEKDSGEEEKEEKEDPTLPKPKPAKIQTKKIKSRGPAGGQGGRPKEKTVKKSLSSESTIPLAPVLGGKEEQGNSELGHPGPKKKFKAPESKASATTLPEKQEIKIVSKCPTPPAGHGVCRLGKEGPGPQEPLTQEAAIFPLEDDGSSDLDLEQLMEDIGETEERGESQQRDGSEGFLAALFEE", "length": 629, "header": "tr|A0A9J7JNC2-1|A0A9J7JNC2_CRIGR Computationally mapped isoform of Zinc finger CW-type PWWP domain protein 1 isoform X6 OS=Cricetulus griseus OX=10029 GN=Zcwpw1 PE=4 SV=1 CANONICAL=A0A061I3R0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 570, "start_aa": "Thr", "end_pos": 570, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr570", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I3R0", "url": "https://www.uniprot.org/uniprotkb/A0A061I3R0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I3R0", "url": "https://www.uniprot.org/uniprotkb/A0A061I3R0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754258", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754258", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0L8H6-1", "protein_name": "Zinc finger CW-type and PWWP domain containing 1", "gene_name": "Zcwpw1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMLRPLRPRGGEYDVVSLGKESVVSELMAALQSHREYEKGTKKTFAPPTQKSHIEKPRPNSWKEDTPGTSSLEAETKPSLLKASLKKKQKATTEHGPSRGQEKKQKAHDQPAEKKGKEKTLTSAEFEEIFQIVLQKSLQECLETSCIQRIRPTKSDKEPGIAPSATDKENADPEKVITPDTPDIASSVEEGVNSEMGTSSLCQPGTEPSKKKWDRRSLSKQKKKAEDEKMEKIQDERECTLKEKQKIMIRDQKEEEGSFGHCVIWVQCSSPKCEKWRQLRGDIDPSVLPDDWSCDQNPDLNYNRCDIPEESWTGCESDVAYASYVPGSIVWAKQYGYPWWPGMIECDPDLGEYFLFASHLDSLPSKYHVTFFGEAVSRAWIPVRMLKNFQELSLELARLKKCKNKDSTQKLEAAISMAHRAEQINIQERVNLFGFWSRYNGADIGEGKDWMLCESNSPESCLEKEEKNSEEEKEEEGGKKDPTLPRPKPAKIQRKRPKSRGPVGGQDGTPKKKTVKKSLVSESTVPPGPTLRGKEEQGNSDLDHPGPKKKFKAPENKASVNNLSEEKEIKIVSKCPAPPAQHGVYTLGKDGLEPQVPLTQGATSFPPDDDGSSDLDLEQLMEDIGEPEERGEMQQRGSSEEFLAALFEE", "length": 649 }, "evidence": [ { "id": "A0A061I3R0", "url": "https://omabrowser.org/oma/group/A0A061I3R0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6IR42-1", "protein_name": "Zinc finger CW-type PWWP domain protein 1", "gene_name": "Zcwpw1", "tax_id": 10090, "organism": "Mus musculus", 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"name": "histone H3K36me3 reader activity", "id": "GO:0140003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140003", "evidence": [ { "database": "UniProtKB", "id": "A0A061I3R0", "url": "https://www.uniprot.org/uniprotkb/A0A061I3R0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0A061I3R0", "url": "https://www.uniprot.org/uniprotkb/A0A061I3R0" } ], "pmid": "" }, { "name": "double-strand break repair involved in meiotic recombination", "id": "GO:1990918", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990918", "evidence": [ { "database": "UniProtKB", "id": "A0A061I3R0", "url": "https://www.uniprot.org/uniprotkb/A0A061I3R0" } ], "pmid": "" }, { "name": "positive regulation of double-strand break repair", "id": "GO:2000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000781", "evidence": [ { "database": "UniProtKB", "id": "A0A061I3R0", "url": "https://www.uniprot.org/uniprotkb/A0A061I3R0" } ], "pmid": "" }, { "name": "positive regulation of DNA recombination", "id": "GO:0045911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045911", "evidence": [ { "database": "UniProtKB", "id": "A0A061I3R0", "url": "https://www.uniprot.org/uniprotkb/A0A061I3R0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 286, "end_pos": 288, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061I3R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I3R0" }, { "id": "PS51050", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51050" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CW-type", "eco_id": 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{ "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061I4B3-1", "uniprot_ac": "A0A061I4B3", "uniprot_id": "A0A061I4B3_CRIGR", "mass": { "chemical_mass": 24581.0, "monoisotopic_mass": 24581.0 }, "refseq": { "ac": "XP_003507810", "name": "CD209 antigen-like protein E", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507810" }, "gene_names": [ { "name": "LOC100772951", "type": "recommended", "evidence": [ { "id": "A0A061I4B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I4B3" } ] }, { "name": "LOC100772951", "type": "synonym", "evidence": [ { "id": "XP_003507810", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507810" } ] } ], "protein_names": [ { "name": "CD209 antigen-like protein E", "type": "synonym", "evidence": [ { "id": "XP_003507810", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507810" }, { "id": "A0A061I4B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I4B3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 7% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614420.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003507810", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507810" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061I4B3", "url": "https://www.uniprot.org/uniprotkb/A0A061I4B3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100772951", "url": "https://www.uniprot.org/uniprotkb/A0A061I4B3", "locus": {} } ], "crossref": [ { "id": "cd03590", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03590", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100772951", "url": "https://www.ncbi.nlm.nih.gov/gene/100772951", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018378", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018378", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772951", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772951", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061I4B3", "url": "https://www.orthodb.org/?gene=A0A061I4B3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46746", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46746", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46746:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46746:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003507810", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507810", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061I4B3", "url": "https://www.uniprot.org/uniprotkb/A0A061I4B3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I4B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I4B3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTVSDSKARVQQMGCLGFLDRGHISLVLQLLLLILFAGLLAAIIIQVSKIPSSEEMQLEETKQEKMYRDLSQLKSEVDSLCRHCPWDWTFFNGNCYFFSKSKRNWHDSITACQEVGAQLVIVKSHEEQSFLQQTSKKNGYTWMGLSDLNKEGAWYWLDDSPLSDRLGKYWNRGQPNNIGGQDCVEFRDEGWNDAKCDEMKLWICKKSATTCSSK", "length": 214, "header": "tr|A0A061I4B3-1|A0A061I4B3_CRIGR Isoform 1 of CD209 antigen-like protein E OS=Cricetulus griseus OX=10029 GN=LOC100772951 PE=4 SV=1 CANONICAL=A0A061I4B3-1" }, "isoforms": [ { "isoform_ac": "A0A061I4B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I4B3/entry#A0A061I4B3-1", "sequence": { "sequence": "MTVSDSKARVQQMGCLGFLDRGHISLVLQLLLLILFAGLLAAIIIQVSKIPSSEEMQLEETKQEKMYRDLSQLKSEVDSLCRHCPWDWTFFNGNCYFFSKSKRNWHDSITACQEVGAQLVIVKSHEEQSFLQQTSKKNGYTWMGLSDLNKEGAWYWLDDSPLSDRLGKYWNRGQPNNIGGQDCVEFRDEGWNDAKCDEMKLWICKKSATTCSSK", "length": 214, "header": "tr|A0A061I4B3-1|A0A061I4B3_CRIGR Isoform 1 of CD209 antigen-like protein E OS=Cricetulus griseus OX=10029 GN=LOC100772951 PE=4 SV=1 CANONICAL=A0A061I4B3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I4B3", "url": "https://www.uniprot.org/uniprotkb/A0A061I4B3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15729:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007645580", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645580", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061I4J5", "url": "https://www.uniprot.org/uniprotkb/A0A061I4J5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I4J5-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I4J5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKSRQKGKKKGYSKERVFGCDLQEHLQHSGQDVPQVLRSCAEFVQEYGVVDGIYRLSGVSSNIQKLRQEFEVERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVAVQLEPERLIKILEVLQELPAPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNLLRSKDIEASGFNGTAAFMEVRVQSIVVEFILTHVDQLFGGASLSDLESGWKSLPGARASGSSEDNMPRSLPYNLPSILQAGDGPPQIRPYHTIIEIAEHKRKGSLKVRKWRSIFNLGRSGHETKRKLPLRTEDREEKSSKGVLRPAKSMDSLSAAAGAIDEPEGLVGPSSSQSSSLVSENLESNSMEAAEGEQEPESEASGSANSEPGTPRAGRSAIRASGSSRAERCAGVHISDPYNVNLPLHITSILSVPPNIISNVSLVRLTRGLECPALQPRPSPASGPVPGPGPPDEKSEARSVPGPLADSSPEDMTPALEDSLSQEVQDSFSFLEDLSSSEPEWVGVEDREVAKAGASGAAGAAAFSLGEDDPGMGYLEEILGDGPQVEEFSVEPPLDDLSLEDAQYVLAPSCCSPDFDDPTPGAEDDNGEEIFLSAYDDLSPLLGPRPMNWEGAGSLQEEAARCEKQPPIQAEEKQACWEAEENKEAEPGSTSDNREDAEAIPEPGMEAGKADEGGGEAEISQKVMGGFEEGGDEEIETTEENAKGQEVESIGAKDMEETRGEGDKDKKESEIGRKEGAEKGEDIPVESGMDPEHSVQDNLLRGESWEAVHTREAEKGEKDENSDHKPREDRGHGGASGSPEEEDGEEGEVSKEQKSIDIGTEGKRAVGDQLEEGTFSEGPGVEFLEVDSTEEVNEQSSQMEQGPPQPSEPEGMEAEEQLSPEACDLYSCPCGSSGGVGMRLASTLIQVQQVRSVPVVPPKPQFAKMPNAMCSKIHVAPASPCPRPGRLDGTPGERAWGSRASWRNGGSLSFDAAVALARERQRTEAQGIRRTQTCTGGGDYSLNSRTSPCSMTPAHSSRPLSCLELPPEGTEGSEPRGRFSLPPRELQLPVPLMSPQRQTYAFETQTNRGKEGL", "length": 1089, "header": "tr|A0A061I4J5-1|A0A061I4J5_CRIGR Isoform 1 of Rho GTPase-activating protein 30 OS=Cricetulus griseus OX=10029 GN=Arhgap30 PE=4 SV=1 CANONICAL=A0A061I4J5-1" }, "isoforms": [ { "isoform_ac": "A0A061I4J5-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I4J5/entry#A0A061I4J5-1", "sequence": { "sequence": "MKSRQKGKKKGYSKERVFGCDLQEHLQHSGQDVPQVLRSCAEFVQEYGVVDGIYRLSGVSSNIQKLRQEFEVERKPDLRRDVYLQDIHCVSSLCKAYFRELPDPLLTYRLYDKFAEAVAVQLEPERLIKILEVLQELPAPNYRTLEFLMRHLVHMASFSAQTNMHARNLAIVWAPNLLRSKDIEASGFNGTAAFMEVRVQSIVVEFILTHVDQLFGGASLSDLESGWKSLPGARASGSSEDNMPRSLPYNLPSILQAGDGPPQIRPYHTIIEIAEHKRKGSLKVRKWRSIFNLGRSGHETKRKLPLRTEDREEKSSKGVLRPAKSMDSLSAAAGAIDEPEGLVGPSSSQSSSLVSENLESNSMEAAEGEQEPESEASGSANSEPGTPRAGRSAIRASGSSRAERCAGVHISDPYNVNLPLHITSILSVPPNIISNVSLVRLTRGLECPALQPRPSPASGPVPGPGPPDEKSEARSVPGPLADSSPEDMTPALEDSLSQEVQDSFSFLEDLSSSEPEWVGVEDREVAKAGASGAAGAAAFSLGEDDPGMGYLEEILGDGPQVEEFSVEPPLDDLSLEDAQYVLAPSCCSPDFDDPTPGAEDDNGEEIFLSAYDDLSPLLGPRPMNWEGAGSLQEEAARCEKQPPIQAEEKQACWEAEENKEAEPGSTSDNREDAEAIPEPGMEAGKADEGGGEAEISQKVMGGFEEGGDEEIETTEENAKGQEVESIGAKDMEETRGEGDKDKKESEIGRKEGAEKGEDIPVESGMDPEHSVQDNLLRGESWEAVHTREAEKGEKDENSDHKPREDRGHGGASGSPEEEDGEEGEVSKEQKSIDIGTEGKRAVGDQLEEGTFSEGPGVEFLEVDSTEEVNEQSSQMEQGPPQPSEPEGMEAEEQLSPEACDLYSCPCGSSGGVGMRLASTLIQVQQVRSVPVVPPKPQFAKMPNAMCSKIHVAPASPCPRPGRLDGTPGERAWGSRASWRNGGSLSFDAAVALARERQRTEAQGIRRTQTCTGGGDYSLNSRTSPCSMTPAHSSRPLSCLELPPEGTEGSEPRGRFSLPPRELQLPVPLMSPQRQTYAFETQTNRGKEGL", "length": 1089, "header": "tr|A0A061I4J5-1|A0A061I4J5_CRIGR Isoform 1 of Rho GTPase-activating protein 30 OS=Cricetulus griseus OX=10029 GN=Arhgap30 PE=4 SV=1 CANONICAL=A0A061I4J5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I4J5", "url": "https://www.uniprot.org/uniprotkb/A0A061I4J5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I4J5", "url": "https://www.uniprot.org/uniprotkb/A0A061I4J5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765257", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765257", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A061I4J5", "url": "https://www.uniprot.org/uniprotkb/A0A061I4J5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A061I4J5", "url": "https://www.uniprot.org/uniprotkb/A0A061I4J5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 435, "end_pos": 437, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061I4J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I4J5" }, { "id": "PS50238", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50238" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho-GAP", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 215, "start_aa": "Cys", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 189, "end_pos": 191 }, { "start_pos": 435, "end_pos": 437 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061I4N0-1", "uniprot_ac": "A0A061I4N0", "uniprot_id": "A0A061I4N0_CRIGR", "mass": { "chemical_mass": 34623.0, "monoisotopic_mass": 34623.0 }, "refseq": { "ac": "XP_016836281", "name": "JNK1/MAPK8-associated membrane protein isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016836281" }, "gene_names": [ { "name": "Jkamp", "type": "recommended", "evidence": [ { "id": "A0A061I4N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I4N0" } ] }, { "name": "Jkamp", "type": "synonym", "evidence": [ { "id": "XP_016836281", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016836281" } ] } ], "protein_names": [ { "name": "JNK1/MAPK8-associated membrane protein isoform X2", "type": "synonym", "evidence": [ { "id": "XP_016836281", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016836281" }, { "id": "A0A061I4N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I4N0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 341 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615595.1) and transcript sequence (IACG01052301.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016836281", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016836281" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061I4N0", "url": "https://www.uniprot.org/uniprotkb/A0A061I4N0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Jkamp", "url": "https://www.uniprot.org/uniprotkb/A0A061I4N0", "locus": {} } ], "crossref": [ { "id": "100763824", "url": "https://www.ncbi.nlm.nih.gov/gene/100763824", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008485", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008485", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A061I4N0", "url": "https://www.orthodb.org/?gene=A0A061I4N0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G3X2", "url": "https://www.orthodb.org/?gene=A0A9J7G3X2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12740", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12740", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12740:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12740:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05571", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05571", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016836281", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016836281", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061I4N0", "url": "https://www.uniprot.org/uniprotkb/A0A061I4N0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I4N0-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I4N0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3X2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3X2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G3X2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G3X2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MACLGLYCGKTLLFKNGSNEIYGECGVCPRGQRTNAQKYCQPCTESPELYDWLYLGFMAMLPLVLHWFFIEWYSGKKSSSALFQHITALFECSMAAIITLLVSDPVGVLYIRSCRVLMLSDWYTMLYNPSPDYVTTVHCTHEAVYPLYTIVFVYYAFCLVLMMLLRPLLVKKIACGLGKSERFKSIYAALYFFPILTVLQAVGGGLLYYAFPYIILVLSLVTLAVYMSASEIENCYDLLVRKKRLIVLFSHWLLHAYGIVSISRADRLEHDLPLLALVPTPALFYLFTAKFTEPSRILSEGANGH", "length": 305, "header": "tr|A0A061I4N0-1|A0A061I4N0_CRIGR Isoform 1 of JNK1/MAPK8-associated membrane protein isoform X2 OS=Cricetulus griseus OX=10029 GN=Jkamp PE=4 SV=1 CANONICAL=A0A061I4N0-1" }, "isoforms": [ { "isoform_ac": "A0A061I4N0-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I4N0/entry#A0A061I4N0-1", "sequence": { "sequence": "MACLGLYCGKTLLFKNGSNEIYGECGVCPRGQRTNAQKYCQPCTESPELYDWLYLGFMAMLPLVLHWFFIEWYSGKKSSSALFQHITALFECSMAAIITLLVSDPVGVLYIRSCRVLMLSDWYTMLYNPSPDYVTTVHCTHEAVYPLYTIVFVYYAFCLVLMMLLRPLLVKKIACGLGKSERFKSIYAALYFFPILTVLQAVGGGLLYYAFPYIILVLSLVTLAVYMSASEIENCYDLLVRKKRLIVLFSHWLLHAYGIVSISRADRLEHDLPLLALVPTPALFYLFTAKFTEPSRILSEGANGH", "length": 305, "header": "tr|A0A061I4N0-1|A0A061I4N0_CRIGR Isoform 1 of JNK1/MAPK8-associated membrane protein isoform X2 OS=Cricetulus griseus OX=10029 GN=Jkamp PE=4 SV=1 CANONICAL=A0A061I4N0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G3X2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I4N0/entry#A0A9J7G3X2-1", "sequence": { "sequence": "MAMLPLVLHWFFIEWYSGKKSSSALFQHITALFECSMAAIITLLVSDPVGVLYIRSCRVLMLSDWYTMLYNPSPDYVTTVHCTHEAVYPLYTIVFVYYAFCLVLMMLLRPLLVKKIACGLGKSERFKSIYAALYFFPILTVLQAVGGGLLYYAFPYIILVLSLVTLAVYMSASEIENCYDLLVRKKRLIVLFSHWLLHAYGIVSISRADRLEHDLPLLALVPTPALFYLFTAKFTEPSRILSEGANGH", "length": 248, "header": "tr|A0A9J7G3X2-1|A0A9J7G3X2_CRIGR Computationally mapped isoform of JNK1/MAPK8-associated membrane protein isoform X3 OS=Cricetulus griseus OX=10029 GN=Jkamp PE=4 SV=1 CANONICAL=A0A061I4N0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 280, "start_aa": "Thr", "end_pos": 280, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr280", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I4N0", "url": "https://www.uniprot.org/uniprotkb/A0A061I4N0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A061I4N0", "url": "https://www.uniprot.org/uniprotkb/A0A061I4N0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin protein ligase binding", "id": "GO:0031625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031625", "evidence": [ { "database": "UniProtKB", "id": "A0A061I4N0", "url": "https://www.uniprot.org/uniprotkb/A0A061I4N0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "A0A061I4N0", "url": "https://www.uniprot.org/uniprotkb/A0A061I4N0" } ], "pmid": "" }, { "name": "response to unfolded protein", "id": "GO:0006986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006986", "evidence": [ { "database": "UniProtKB", "id": "A0A061I4N0", "url": "https://www.uniprot.org/uniprotkb/A0A061I4N0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 16, "end_pos": 18, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", 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"mass": { "chemical_mass": 60642.0, "monoisotopic_mass": 60642.0 }, "refseq": { "ac": "XP_007639000", "name": "coiled-coil domain-containing protein 82 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639000" }, "gene_names": [ { "name": "Ccdc82", "type": "recommended", "evidence": [ { "id": "A0A061I4R7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I4R7" } ] }, { "name": "Ccdc82", "type": "synonym", "evidence": [ { "id": "XP_007639000", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639000" } ] } ], "protein_names": [ { "name": "Coiled-coil domain-containing protein 82 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A061I4R7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I4R7/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 82 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007639000", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639000" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613772.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007639000", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639000" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061I4R7", "url": "https://www.uniprot.org/uniprotkb/A0A061I4R7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ccdc82", "url": "https://www.uniprot.org/uniprotkb/A0A061I4R7", "locus": {} } ], "crossref": [ { "id": "100762899", "url": "https://www.ncbi.nlm.nih.gov/gene/100762899", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025451", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025451", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762899", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762899", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HYVHFKR", "url": "https://omabrowser.org/oma/group/HYVHFKR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061I4R7", "url": "https://www.orthodb.org/?gene=A0A061I4R7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14689", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14689", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14689:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14689:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13846", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13846", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13926", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13926", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007639000", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007639000", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061I4R7", "url": "https://www.uniprot.org/uniprotkb/A0A061I4R7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I4R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I4R7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K6C8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6C8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K6C8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K6C8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVHVRRHETRKNSKTQVPEQKSRVDWRRTKRSISQLFDSDEELDSDEELEVDSDEELESGESVDSGEELDSSKNPGISEIPEKETEPKLIKVETEGSNSKPLTNTSNSSTDEEKMNKTEHDLPDDENRPSGQEKGDVNRHTKQSVEEDMEDEYIKPGKRKRLSSVMYDSDDSDDSDILVRKVSAKRPRRVVEDECSSLETEQETPEKSLAARKREHHQKLKELSERSRQRQRRNSGRNFEDSEKESCSSTDEDEDEDDYKYDENGDDYMIDDFVVQDEEGDEENKNQQGENLTTSQLKLVKQNSLYSFSDHYTHFETVVKALLINAFDESFLETLYAGTRKKSYAQDMLTSLHYLDNRFIQPRLESLVSRSRWKEQYKERVESYSTLSIHSKNPADCSCQACGLHRHCVYSVHLSGKLYNTRTMETDDFMSHDKQVFTVGRICADRTRIYHKLKHFKFKLYQECCSIAKTEEDGDEQVKETVGRVFSQSKESGWIRKKYDQLQDYLNSADYFQDEKFEL", "length": 519, "header": "tr|A0A061I4R7-1|A0A061I4R7_CRIGR Isoform 1 of Coiled-coil domain-containing protein 82 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ccdc82 PE=4 SV=1 CANONICAL=A0A061I4R7-1" }, "isoforms": [ { "isoform_ac": "A0A061I4R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I4R7/entry#A0A061I4R7-1", "sequence": { "sequence": "MVHVRRHETRKNSKTQVPEQKSRVDWRRTKRSISQLFDSDEELDSDEELEVDSDEELESGESVDSGEELDSSKNPGISEIPEKETEPKLIKVETEGSNSKPLTNTSNSSTDEEKMNKTEHDLPDDENRPSGQEKGDVNRHTKQSVEEDMEDEYIKPGKRKRLSSVMYDSDDSDDSDILVRKVSAKRPRRVVEDECSSLETEQETPEKSLAARKREHHQKLKELSERSRQRQRRNSGRNFEDSEKESCSSTDEDEDEDDYKYDENGDDYMIDDFVVQDEEGDEENKNQQGENLTTSQLKLVKQNSLYSFSDHYTHFETVVKALLINAFDESFLETLYAGTRKKSYAQDMLTSLHYLDNRFIQPRLESLVSRSRWKEQYKERVESYSTLSIHSKNPADCSCQACGLHRHCVYSVHLSGKLYNTRTMETDDFMSHDKQVFTVGRICADRTRIYHKLKHFKFKLYQECCSIAKTEEDGDEQVKETVGRVFSQSKESGWIRKKYDQLQDYLNSADYFQDEKFEL", "length": 519, "header": "tr|A0A061I4R7-1|A0A061I4R7_CRIGR Isoform 1 of Coiled-coil domain-containing protein 82 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ccdc82 PE=4 SV=1 CANONICAL=A0A061I4R7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K6C8-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I4R7/entry#A0A9J7K6C8-1", "sequence": { "sequence": "MVHVRRHETRKNSKTQVPEQKSRVDWRRTKRSISQLFDSDEELDSDEELEVDSDEELESGESVDSGEELDSSKNPGISEIPEKETEPKLIKVETEGSNSKPLTNTSNSSTDEEKMNKTEHDLPDDENRPSGQEKGDVNRHTKQSVEEDMEDEYIKPGKRKRLSSVMYDSDDSDDSDILVRKVSAKRPRRVVEDECSSLETEQETPEKSLAARKREHHQKLKELSERSRQRQRRNSGRNFEDSEKESCSSTDEDEDEDDYKYDENGDDYMIDDFVVQDEEGDEENKNQQGENLTTSQLKLVKQNSLYSFSDHYTHFETVVKALLINAFDESFLETLYAGTRKKSYAQDMLTSLHYLDNRFIQPRLESLVSRSRWKEQYKERVESYSTLSIHSKNPADCSCQACGLHRHCVYSVHLSGKLYNTRTMETDDFMSHDKQKYDQLQDYLNSADYFQDEKFEL", "length": 457, "header": "tr|A0A9J7K6C8-1|A0A9J7K6C8_CRIGR Computationally mapped isoform of Coiled-coil domain-containing protein 82 isoform X2 OS=Cricetulus griseus OX=10029 GN=Ccdc82 PE=4 SV=1 CANONICAL=A0A061I4R7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I4R7", "url": "https://www.uniprot.org/uniprotkb/A0A061I4R7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I4R7", "url": "https://www.uniprot.org/uniprotkb/A0A061I4R7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762899", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762899", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TVQ8-1", "protein_name": "Coiled-coil domain containing 82", "gene_name": "CCDC82", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVHVRRCETRKSSKTQECEQKSRVDWRRTKRSSLSQLCDSDDELESDDEFDSDESVDNNASIDSDEELDNSKGLDSIKKPENERELKLIKVESEGNNSEHLINTSNTSVYEEEKNKTKHESINLSDHREHSSQEEDDLNIHTGQITEEDLEEEHIKRGKRKRISSVMYDSDESDDSDILVRKVGIKRPRRVVEDECSSVEMEQKNPEKALAAKKQEQLQKLKELSKQRSRQRRTSSRDFEDSEKESCSSSDENEEEEEEENYEDGDDYIIDDFVVKDEEGDEENKSQQGEKLTTSQLKLVKQNSLYSFSDHYTHFERVVKALLINALDDSFLETLYDGTRQKSYAKDMLTSLDYLDNRFVQPRLESLVSRSRWKEQYKERVENYSNVTIHSKNPEDCSCQACGLHRRCSYSVHLSGKLYNTRTMETDDFMSQDKQVFTVGRICANRTRIYHTLKHFKFKLYQECCSIAKTEEVEDEQVKETVERIFNQSKERGWIEEKYGQLQEYLNCADYFQDEKFD", "length": 518 }, "evidence": [ { "id": "A0A061I4R7", "url": "https://omabrowser.org/oma/group/A0A061I4R7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1MEZ4-1", "protein_name": "Coiled-coil domain containing 82", "gene_name": "CCDC82", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVHVRRHETRKNSKTQGHEQKSRVDWRRTKRNSLLQLCESGDELESDEGVDSNESVDSDEDPDSNKGPDCIEKPEDERELKLINVEGEGNSSKHLINTDNSSTYEEEKNKTKHGSIDLADHEKGPGQEEGDLNKHTGQITEEDLEEEHIKRGKRKRISSVMCDSDESDDSDILVRKVGVKRPRRVVEDECSSVEMEQKNPEKTSATRRREQLQKLEELSKQRSRQRHNSSRDFEDSEKKSSPSSDENDVEEEEEEDNDYEFDEDEIIDEDGDHYIIDGFVVQDEEGDEENKSQQGEQLTTSQRKSIKQNSFCDHYTHFERVVKALLINALDESFLGTLYDGTRQKSYAQDMLTSLYYLDNRFVQPRLENLVSRSRWKEKYKERVENYSSVDIQLKTSENCLCQACGLYRHCEYSVHLSGKLYDTRTMETDDFMSHDKQVFTVGRICAERTRIYHKLKHFKFELYQECCSIAKTEEVEDEEVKETVERIFSQSENSGWIKEKYGQLQEYLNLADYFKEEKFEF", "length": 522 }, "evidence": [ { "id": "A0A061I4R7", "url": "https://omabrowser.org/oma/group/A0A061I4R7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q66H73-1", "protein_name": "Coiled-coil domain-containing protein 82", "gene_name": "Ccdc82", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVHARRHETRKNSKTQVPEQKSRVDWRRTKRSVSQLFDSDEELDSDEEIGSDEDLDGGESIDSDGKLDISKDSGINEIPEKETELNLIKVESERSNSKCHMNTSSSSADEEEMNKTKHNDLPDDEAHPGQAEGHHNKLTGQVLEEDVEDECIKPGKRKRLSSVMYDSDESDDSDILVRKASAKHPRRVVEDECSSLEMERETPEKSPAARKREYHQKLQELCERSRQKQRHNSGRNCESSEKDSCSSTDEDEDDDDYGDAENEDDYMIDDFVVGDEEADEENKNQGENLTTSQLKLVKQNSLYSFSDHYTHFERVVKALLINAFDGSFLETLYAGKRKKSYAQDMLTSLHYLDDRFIQPRLESLVSRSRWREQYKERVESYSDLSIHWKSPENCGCQACGLHRYCKFSVRLSGKLYNTRTMETDDFMSRDKQVFIVGRICAERTKIYHKLKHFKFKLYQDCCSIAYTKEVGDEQVKDTVKRLFCQLKKSGWIRKKHGQLEEYLNSADYFQDEKFKL", "length": 516 }, "evidence": [ { "id": "A0A061I4R7", "url": "https://omabrowser.org/oma/group/A0A061I4R7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6PG04-1", "protein_name": "Coiled-coil domain-containing protein 82", "gene_name": "Ccdc82", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVHVRRHETRKNSKTQKPEQKSRVDWHRTKRSISQLFDSDEELDSNEELDSDEEHDSGESIDSDEELDISKKSDINELPEKETELKLIKVESQGSNSKHLTNTSNSSADEEQLKETKHNDLPDDEAHPGQAENHHNRHTGQILEEDMEDEYIKPGKRKRLSSVMYDSDESDDSDILIRKASAKHPRRVVEDECSSLEMEQETPEKSSAARKREYHQKLQELSERSRQRRRRNSGRNFEDSEKDSCSGTGEEDEDEDEDDYRYDEDGDDYMIDDFVVRNEEGDDENSNQQGENLTTSQLKLVKQNSLYSFSDHYTHFERVVKALLINAFDESFLETLYAGTRKKSYAKDMLTSLHYLDNRFIQPRLESLVSRSRWKEQYKERVESYSNLNILSKSPENCVCQACGLHRHCKFSVHLSGKLYNIRTMETDDFMSHDKQVFTVGRICVERTRIYHKLKHFKFKLYQDCCLIAKPEEVGDEQVKDTVKRVFNHSKERGWIRKKYDQLQNFLNSADYFQDEKF", "length": 518 }, "evidence": [ { "id": "A0A061I4R7", "url": "https://omabrowser.org/oma/group/A0A061I4R7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N4S0-1", "protein_name": "Coiled-coil domain-containing protein 82", "gene_name": "CCDC82", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIHVRRHETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFENDEELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESDEDGDDYIIDDFVVQDEEGDEENKNQQGEKLTTSQLKLVKQNSLYSFSDHYTHFERVVKALLINALDESFLGTLYDGTRQKSYAKDMLTSLHYLDNRFVQPRLESLVSRSRWKEQYKERVENYSNVSIHLKNPENCSCQACGLHRYCKYSVHLSGELYNTRTMQIDNFMSHDKQVFTVGRICASRTRIYHKLKHFKFKLYQECCTIAMTEEVEDEQVKETVERIFRRSKENGWIKEKYGQLEEYLNFADYFQEEKFEL", "length": 544 }, "evidence": [ { "id": "A0A061I4R7", "url": "https://omabrowser.org/oma/group/A0A061I4R7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A061I4R7", "url": "https://www.uniprot.org/uniprotkb/A0A061I4R7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 116, "end_pos": 118, "annotation": "n_glycosylation_sequon" }, { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061I4R7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I4R7" }, { "id": "PF13846", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13846" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Coiled-coil", "eco_id": "ECO_0000259", "start_pos": 104, "end_pos": 213, "start_aa": "Asn", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A061I4R7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I4R7" }, { "id": "PF13926", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13926" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF4211", "eco_id": "ECO_0000259", "start_pos": 272, "end_pos": 424, "start_aa": "Asp", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 }, { "start_pos": 107, "end_pos": 109 }, { "start_pos": 116, "end_pos": 118 }, { "start_pos": 291, "end_pos": 293 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7H9D8-1", "uniprot_ac": "A0A3L7H9D8", "uniprot_id": "A0A3L7H9D8_CRIGR", "mass": { "chemical_mass": 32961.0, "monoisotopic_mass": 32961.0 }, "refseq": { "ac": "XP_027285215", "name": "WW domain-binding protein 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285215" }, "gene_names": [ { "name": "Wbp1", "type": "recommended", "evidence": [ { "id": "A0A3L7H9D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9D8" } ] }, { "name": "Wbp1", "type": "synonym", "evidence": [ { "id": "XP_027285215", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285215" } ] } ], "protein_names": [ { "name": "WW domain-binding protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027285215", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285215" }, { "id": "A0A3L7H9D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9D8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027285215", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285215" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H9D8", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9D8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Wbp1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9D8", "locus": {} } ], "crossref": [ { "id": "100762371", "url": "https://www.ncbi.nlm.nih.gov/gene/100762371", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR021684", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021684", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762371", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762371", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NGSHETW", "url": "https://omabrowser.org/oma/group/NGSHETW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7H9D8", "url": "https://www.orthodb.org/?gene=A0A3L7H9D8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16209", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16209", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16209:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16209:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11669", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11669", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027285215", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285215", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7H9D8", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9D8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7H9D8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9D8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3I7V7", "url": "https://www.uniprot.org/uniprotkb/G3I7V7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3I7V7-1", "url": "https://www.uniprot.org/uniprotkb/G3I7V7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARASSRNSSEEAWGAHRAPQQQSPAASSLEGAIWKRAGTQTRALDAILYHPQQSHLLQELCPGVNTQPYLCESGHCCGETGCCTYYYELWWFWLLWTVLILFSCCCAFRHRRAKLRLQQQQRQREINLLAYHGACHGAGPVPTGSLLDLRLLSAFKPPAYEDVVHHPGTPPPPYTLTLGHPSSASSEHICCSSASSCSAHLEGTNVEGVSSHQSALPHQEGEPRAGLSPVHTPPSCRYRRLTGDSGIELCPCPDSREGEPVKEMRASATQPDLGDHSPCVLSPDSMSQTPPLGLASSYGDIP", "length": 303, "header": "tr|A0A3L7H9D8-1|A0A3L7H9D8_CRIGR Isoform 1 of WW domain-binding protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Wbp1 PE=4 SV=1 CANONICAL=A0A3L7H9D8-1" }, "isoforms": [ { "isoform_ac": "A0A3L7H9D8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9D8/entry#A0A3L7H9D8-1", "sequence": { "sequence": "MARASSRNSSEEAWGAHRAPQQQSPAASSLEGAIWKRAGTQTRALDAILYHPQQSHLLQELCPGVNTQPYLCESGHCCGETGCCTYYYELWWFWLLWTVLILFSCCCAFRHRRAKLRLQQQQRQREINLLAYHGACHGAGPVPTGSLLDLRLLSAFKPPAYEDVVHHPGTPPPPYTLTLGHPSSASSEHICCSSASSCSAHLEGTNVEGVSSHQSALPHQEGEPRAGLSPVHTPPSCRYRRLTGDSGIELCPCPDSREGEPVKEMRASATQPDLGDHSPCVLSPDSMSQTPPLGLASSYGDIP", "length": 303, "header": "tr|A0A3L7H9D8-1|A0A3L7H9D8_CRIGR Isoform 1 of WW domain-binding protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Wbp1 PE=4 SV=1 CANONICAL=A0A3L7H9D8-1" }, "locus": {} }, { "isoform_ac": "G3I7V7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9D8/entry#G3I7V7-1", "sequence": { "sequence": "MARASSRNSSEEAWGAHRAPQQQLQELCPGVNTQPYLCESGHCCGETGCCTYYYELWWFWLLWTVLILFSCCCAFRHRRAKLRLQQQQRQREINLLAYHGACHGAGPVPTGSLLDLRLLSAFKPPAYEDVVHHPGTPPPPYTLTLGHPSSASSEHICCSSASSCSAHLEGTNVEGVSSHQSALPHQEGEPRAGLSPVHTPPSCRYRRLTGDSGIELCPCPDSREGEPVKEMRASATQPDLGDHSPCVLSPDSMSQTPPLGLASSYGDIP", "length": 269, "header": "tr|G3I7V7-1|A0A3L7H9D8_CRIGR Computationally mapped isoform of WW domain-binding protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Wbp1 PE=4 SV=1 CANONICAL=A0A3L7H9D8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3I7V7", "url": "https://www.uniprot.org/uniprotkb/G3I7V7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3I7V7", "url": "https://www.uniprot.org/uniprotkb/G3I7V7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762371", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762371", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K3J0-1", "protein_name": "WW domain binding protein 1", "gene_name": "Wbp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARASSRNSSEEAWGALQAPQQQSPAASSLEGAIWRRAGTQTRALDAILYHPQQSHLLRELCPGVNTQPYLCESGHCCGETGCCTYYYELWWFWLLWTVLILFSCCCAFRHRRAKLRLQQQQRQREINLLAYHGACHGAGPVPTGSLLDLRLLSAFKPPAYEDVVHHPGTPPPPYTMAPGHPLTTSNECTRCSSESSCSAQSEGTSVEGVSSNQSALPPQEGEPRAGVSPVHTPPSCRYRHLTGDSGIELCPCPDSSEGELVKELRASATQPDLEDHSPCALPPEPMSQVPPVGLASSYGDIP", "length": 303 }, "evidence": [ { "id": "A0A3L7H9D8", "url": "https://omabrowser.org/oma/group/A0A3L7H9D8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A287BLW9-1", "protein_name": "WW domain binding protein 1", "gene_name": "WBP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARASGGNGSEEAWGALRVPQQQSPAASSLEGAIWRRAGAQTRALDAIIYHPQHSPLLRELCPGVNNQPYLCESGHCCGETGCCTYYYELWWFWLLWTVLILFSCCCAFRHRRAKLRLQQQQRQREINLLAYHGACHGAGPAPAGSLLDLRLLSAFKPPAYEDVVHRPGTPPPPYTAASGCPSTASSECTCSSSASSCPAHREGTNVEGVSSHQSTPLHQEGEPGAGVSPAPTPPSCRYRRLTGDSGIELCPCPDSSEGEPAEEARAGATPPDVEGQSPCAPPLNPIPQVSPLGLASSEGDIP", "length": 303 }, "evidence": [ { "id": "A0A3L7H9D8", "url": "https://omabrowser.org/oma/group/A0A3L7H9D8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97764-1", "protein_name": "WW domain-binding protein 1", "gene_name": "Wbp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARASSRNSSEEAWGSLQAPQQQQSPAASSLEGAIWRRAGTQTRALDTILYHPQQSHLLRELCPGVNTQPYLCETGHCCGETGCCTYYYELWWFWLLWTVLILFSCCCAFRHRRAKLRLQQQQRQREINLLAYHGACHGAGPVPTGSLLDLRLLSAFKPPAYEDVVHHPGTPPPPYTVGPGYPWTTSSECTRCSSESSCSAHLEGTNVEGVSSQQSALPHQEGEPRAGLSPVHIPPSCRYRRLTGDSGIELCPCPDSSEGEPLKEARASASQPDLEDHSPCALPPDSVSQVPPMGLASSCGDIP", "length": 304 }, "evidence": [ { "id": "A0A3L7H9D8", "url": "https://omabrowser.org/oma/group/A0A3L7H9D8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96G27-1", "protein_name": "WW domain-binding protein 1", "gene_name": "WBP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARASSGNGSEEAWGALRAPQQQLRELCPGVNNQPYLCESGHCCGETGCCTYYYELWWFWLLWTVLILFSCCCAFRHRRAKLRLQQQQRQREINLLAYHGACHGAGPFPTGSLLDLRFLSTFKPPAYEDVVHRPGTPPPPYTVAPGRPLTASSEQTCCSSSSSCPAHFEGTNVEGVSSHQSAPPHQEGEPGAGVTPASTPPSCRYRRLTGDSGIELCPCPASGEGEPVKEVRVSATLPDLEDYSPCALPPESVPQIFPMGLSSSEGDIP", "length": 269 }, "evidence": [ { "id": "A0A3L7H9D8", "url": "https://omabrowser.org/oma/group/A0A3L7H9D8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "WW domain binding", "id": "GO:0050699", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050699", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H9D8", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9D8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061IMU8-1", "uniprot_ac": "A0A061IMU8", "uniprot_id": "A0A061IMU8_CRIGR", "mass": { "chemical_mass": 91200.0, "monoisotopic_mass": 91200.0 }, "refseq": { "ac": "XP_007644033", "name": "activating signal cointegrator 1 complex subunit 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644033" }, "gene_names": [ { "name": "Ascc2", "type": "recommended", "evidence": [ { "id": "A0A061IMU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IMU8" } ] }, { "name": "Ascc2", "type": "synonym", "evidence": [ { "id": "XP_007644033", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644033" } ] } ], "protein_names": [ { "name": "Activating signal cointegrator 1 complex subunit 2 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A061IMU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IMU8/entry#names_and_taxonomy" } ] }, { "name": "activating signal cointegrator 1 complex subunit 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007644033", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644033" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614142.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007644033", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644033" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IMU8", "url": "https://www.uniprot.org/uniprotkb/A0A061IMU8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ascc2", "url": "https://www.uniprot.org/uniprotkb/A0A061IMU8", "locus": {} } ], "crossref": [ { "id": "cd14364", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14364", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100775056", "url": "https://www.ncbi.nlm.nih.gov/gene/100775056", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041800", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041800", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052586", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052586", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100775056", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100775056", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061IMU8", "url": "https://www.orthodb.org/?gene=A0A061IMU8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3HP16", "url": "https://www.orthodb.org/?gene=G3HP16", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21494", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21494", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21494:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21494:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02845", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02845", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007644033", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644033", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IMU8", "url": "https://www.uniprot.org/uniprotkb/A0A061IMU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IMU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IMU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HP16", "url": 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"MCLLTDSHVSGTDVGAGIQAARQTRRLCSWDLQSRGRRQSTRGSHSTMSALPLDQHQITHKDPKTGKPRTSPALHPEQKADRYFVLYKPPPKDNIPALVEEYLERATFIANDLDWLLALPHDKFWCQVVFDETLQKCLDSYLRYVPRKFDEWVAPTPEVADMQKHLHRSIFLTFLRMSTHKESKDHFISPSVFGEILYNNFLFDIPKILDLCVLFGKGNSPLLQKMIGNIFTQQPSYYNDLDETIPTILQVFSNILQHCGLQGDGTSTTPQKLGEKGRLTPSDMPLLELKDIVLYLCDTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEMAIPEMESAIKKRRLEDSKLLGDMWQRLSHSKKKLMEVFHIILNQICLLPILESSCDNIQGFIEEFLQIFSSLLQEKRFLRDYDSFFPIAEDISLLQQASSALDETRTAYILQAVESAWEGVDRQKIKDIKDPSRAKDANNEVTMTPKPISEMPSSQLENSEEDEECMGAAAALGPTVCGVELDSLISQVKDLLPDLGEGFILACLEHYSYDSEQVINNILEDRLAPELSQLDRSLERQVKPDPTPLLTSRHNVFQNDEFDVFSRDSVDLSRVHKGRRKEENVRSLVNDKRAVVAQWHRYQQYSVVMEEVPLQPGEYQVDDYEDEYDDTYDGNQVGANDADSDDELISRRPFTTPQVLRTKTPGEGQEEEYEVEEVEEEAPKLDHFIQDPAVLREKAEARRMAFLARKGYRPENSAAVTGSPRGHGQSRETTQERRKKEAKKATRANHNRRTMADRKRSKGMIPS", "length": 796, "header": "tr|A0A061IMU8-1|A0A061IMU8_CRIGR Isoform 1 of Activating signal cointegrator 1 complex subunit 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ascc2 PE=4 SV=1 CANONICAL=A0A061IMU8-1" }, "isoforms": [ { "isoform_ac": "A0A061IMU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IMU8/entry#A0A061IMU8-1", "sequence": { "sequence": "MCLLTDSHVSGTDVGAGIQAARQTRRLCSWDLQSRGRRQSTRGSHSTMSALPLDQHQITHKDPKTGKPRTSPALHPEQKADRYFVLYKPPPKDNIPALVEEYLERATFIANDLDWLLALPHDKFWCQVVFDETLQKCLDSYLRYVPRKFDEWVAPTPEVADMQKHLHRSIFLTFLRMSTHKESKDHFISPSVFGEILYNNFLFDIPKILDLCVLFGKGNSPLLQKMIGNIFTQQPSYYNDLDETIPTILQVFSNILQHCGLQGDGTSTTPQKLGEKGRLTPSDMPLLELKDIVLYLCDTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEMAIPEMESAIKKRRLEDSKLLGDMWQRLSHSKKKLMEVFHIILNQICLLPILESSCDNIQGFIEEFLQIFSSLLQEKRFLRDYDSFFPIAEDISLLQQASSALDETRTAYILQAVESAWEGVDRQKIKDIKDPSRAKDANNEVTMTPKPISEMPSSQLENSEEDEECMGAAAALGPTVCGVELDSLISQVKDLLPDLGEGFILACLEHYSYDSEQVINNILEDRLAPELSQLDRSLERQVKPDPTPLLTSRHNVFQNDEFDVFSRDSVDLSRVHKGRRKEENVRSLVNDKRAVVAQWHRYQQYSVVMEEVPLQPGEYQVDDYEDEYDDTYDGNQVGANDADSDDELISRRPFTTPQVLRTKTPGEGQEEEYEVEEVEEEAPKLDHFIQDPAVLREKAEARRMAFLARKGYRPENSAAVTGSPRGHGQSRETTQERRKKEAKKATRANHNRRTMADRKRSKGMIPS", "length": 796, "header": "tr|A0A061IMU8-1|A0A061IMU8_CRIGR Isoform 1 of Activating signal cointegrator 1 complex subunit 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ascc2 PE=4 SV=1 CANONICAL=A0A061IMU8-1" }, "locus": {} }, { "isoform_ac": "G3HP16-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IMU8/entry#G3HP16-1", "sequence": { "sequence": "MRVAGVEPGGGSHSTMSALPLDQHQITHKDPKTGKPRTSPALHPEQKADRYFVLYKPPPKDNIPALVEEYLERATFIANDLDWLLALPHDKFWCQVVFDETLQKCLDSYLRYVPRKFDEWVAPTPEVADMQKHLHRSIFLTFLRMSTHKESKDHFISPSVFGEILYNNFLFDIPKILDLCVLFGKGNSPLLQKMIGNIFTQQPSYYNDLDETIPTILQVFSNILQHCGLQGDGTSTTPQKLGEKGRLTPSDMPLLELKDIVLYLCDTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEMAIPEMESAIKKRRLEDSKLLGDMWQRLSHSKKKLMEVFHIILNQICLLPILESSCDNIQGFIEEFLQIFSSLLQEKRFLRDYDSFFPIAEDISLLQQASSALDETRTAYILQAVESAWEGVDRQKIKDIKDPSRAKDANNEVTMTPKPISEMPSSQLENSEEDEECMGAAAALGPTVCGVELDSLISQVKDLLPDLGEGFILACLEHYSYDSEQVINNILEDRLAPELSQLDRSLERQVKPDPTPLLTSRHNVFQNDEFDVFSRDSVDLSRVHKGRRKEENVRSLVNDKRAVVAQWHRYQQYSVVMEEVPLQPGEYQVDDYEDEYDDTYDGNQVGANDADSDDELISRRPFTTPQVLRTKTPGEGQEEEYEVEEVEEEAPKLDHFIQDPAVLREKAEARRMAFLARKGYRPENSAAVTGSPRGHGQSRETTQERRKKEAKKATRANHNRRTMADRKRSKGMIPS", "length": 764, "header": "tr|G3HP16-1|A0A061IMU8_CRIGR Computationally mapped isoform of Activating signal cointegrator 1 complex subunit 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ascc2 PE=4 SV=1 CANONICAL=A0A061IMU8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 156, "start_aa": "Thr", "end_pos": 156, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr156", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 508, "start_aa": "Thr", "end_pos": 508, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr508", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HP16", "url": "https://www.uniprot.org/uniprotkb/G3HP16" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HP16", "url": "https://www.uniprot.org/uniprotkb/G3HP16" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100775056", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100775056", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "rescue of stalled ribosome", "id": "GO:0072344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072344", "evidence": [ { "database": "UniProtKB", "id": "A0A061IMU8", "url": "https://www.uniprot.org/uniprotkb/A0A061IMU8" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A061IMU8", "url": "https://www.uniprot.org/uniprotkb/A0A061IMU8" } ], "pmid": "" }, { "name": "ribosome-associated ubiquitin-dependent protein catabolic process", "id": "GO:1990116", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990116", "evidence": [ { "database": "UniProtKB", "id": "A0A061IMU8", "url": "https://www.uniprot.org/uniprotkb/A0A061IMU8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A061IMU8", "url": "https://www.uniprot.org/uniprotkb/A0A061IMU8" } ], "pmid": "" }, { "name": "cytosolic ribosome", "id": "GO:0022626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022626", "evidence": [ { "database": "UniProtKB", "id": "A0A061IMU8", "url": "https://www.uniprot.org/uniprotkb/A0A061IMU8" } ], "pmid": "" }, { "name": "RQC-trigger complex", "id": "GO:0180022", "url": 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"domain_list": [ { "evidence": [ { "id": "A0A061IMU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IMU8" }, { "id": "PS51140", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51140" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CUE", "eco_id": "ECO_0000259", "start_pos": 513, "end_pos": 556, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 156, 508 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615225.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003511791", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511791" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061I8E0", "url": "https://www.uniprot.org/uniprotkb/A0A061I8E0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ccdc189", "url": "https://www.uniprot.org/uniprotkb/A0A061I8E0", "locus": {} } ], "crossref": [ { "id": "100751203", "url": "https://www.ncbi.nlm.nih.gov/gene/100751203", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032727", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032727", "database": "InterPro", "categories": [ "Protein Classification" 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] } ], "sequence": { "sequence": "MISPKSSQVLGVKMQSEFEQLPQLEQDLESCARSEGGSVIRTETDVQTESTAEASTSVGVAEDPGANLFPPPLPQPRICMWKYLDIHSMHRLEKAVTVEEMREVLAELLELGCPEQSLRDAIILDLFSHALIFCRQQGFSLEQTSAACALLQDLHKACVATPLGNVEECYRYFTSVLFCHGVRRPPFSIDLFKEEQLLALADYVINTYFRHFKLYKYVFTPQVRLDLSLTYIGLQPPKPWPEEKEGEVLAEQAATPQEEEPETVTQPEQQPSEVCILQTYIKTQLSKELRQLQQLVEERLKESEERLSSKLAALERPYQPPPSKGKTKTK", "length": 330, "header": "tr|A0A061I8E0-1|A0A061I8E0_CRIGR Isoform 1 of Coiled-coil domain-containing protein 189 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ccdc189 PE=4 SV=1 CANONICAL=A0A061I8E0-1" }, "isoforms": [ { "isoform_ac": "A0A061I8E0-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I8E0/entry#A0A061I8E0-1", "sequence": { "sequence": 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Computationally mapped isoform of Coiled-coil domain-containing protein 189 isoform X3 OS=Cricetulus griseus OX=10029 GN=Ccdc189 PE=4 SV=1 CANONICAL=A0A061I8E0-1" }, "locus": {} }, { "isoform_ac": "G3I9T9-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I8E0/entry#G3I9T9-1", "sequence": { "sequence": "MISPKSSQVLGVKMQSEFEQLPQLEQDLESCARSEGGSVIRTETDVQTESTAEASTSVGVAEDPGANLFPPPLPQPRICMWVLAELLELGCPEQSLRDAIILDLFSHALIFCRQQGFSLEQTSAACALLQDLHKACVATPLGNVEECYRYFTSVLFCHGVRRPPFSIDLFKEEQLLALADYVINTYFRHFKLYKYVFTPQVRLDLSLTYIGLQPPKPWPEEKEGEVLAEQAATPQEEEPETVTQPEQQPSEVCILQTYIKTQLSKELRQLQQLVEERLKESEERLSSKLAALERPYQPPPSKGKTKTK", "length": 308, "header": "tr|G3I9T9-1|A0A061I8E0_CRIGR Computationally mapped isoform of Coiled-coil domain-containing protein 189 isoform X1 OS=Cricetulus griseus OX=10029 GN=Ccdc189 PE=4 SV=1 CANONICAL=A0A061I8E0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3I9T9", "url": "https://www.uniprot.org/uniprotkb/G3I9T9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3I9T9", "url": "https://www.uniprot.org/uniprotkb/G3I9T9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751203", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751203", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A1A4V9-1", "protein_name": "Cilia- and flagella-associated protein 119", "gene_name": "CFAP119", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLNRKTSHFLGMRVQSELEHLSELRREAGKDRSSVHGSAARTRASVRTQWTTAAAAKADEDPGANLFPPPLPRPRICMWKYLDVHSMHQLEKTTNAEMREVLAELLELGCPEQSLRDAITLDLFCHALIFCRQQGFSLEQTSAACALLQDLHKACIATPLGNVEECYRYFTSVLFCHGVRRPPFSIDLFKEEQLLALEDYVVNTYFRHFKLYKYVFTPQVRLDLSLTYMGLQPPKLWPESETEKEESKEMEEQAVTPQKEELETVAPPEPEPSHIHVLRAYIKTQVNKELEQLQGLVEERLKASEERLSSKLTALERPFQLPPGKGKSKTK", "length": 331 }, "evidence": [ { "id": "A0A061I8E0", "url": "https://omabrowser.org/oma/group/A0A061I8E0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F1MZI0-1", "protein_name": "Cilia and flagella associated protein 119", "gene_name": "CFAP119", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MIRRKSSQFQGLKMQSELVQHYELRREPEKDLSSLDESATRMGTGVRTESGTVASVDVDNDPSANLFPPPLPQPRICIWKYLDIHSMHMLEKTASTEEMREVLAELLGLGSPEKSLRDAITLDLFSHALIFCRQQGFSLEQTSTACALLQDLHKACIETPLGNVEECYRYFTSVLFCHGVRRPPFSINLFKEEQLLALADYVVNTYFRHFKLYKYVFTPQVRLDLSLTYMGLKPPSLWSEDETEKEKGGEVEQQAVIAQEVEPETVVQPKPEPSQVSILRAYIKNQMNKELRQLQQLVEERLKASEERLSSKLTTLERPLQLPPGKGKNKTK", "length": 332 }, "evidence": [ { "id": "A0A061I8E0", "url": "https://omabrowser.org/oma/group/A0A061I8E0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RG95-1", "protein_name": "Cilia and flagella associated protein 119", "gene_name": "CFAP119", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MIRRKSSQFRRLKRRSELDQHSELRREHEKDHEKDLSSLDESAKRMGTGVRTESGTVASVDANEDPAANLFPPPLPQPRICIWKYLDIHSMQRLEKTTNVEEMREVLAELLGLSCPEQNLRDAITLDLFSHILIFCRHQGFSLEQTSTACALLQDLHKACIATPLGNVEECYRYFTSVLFCHGVRRPPFSINLFKEEQLLALADYVVNTYFRHFKLYKYVFTPQVRLDLSLTYMGLQPPRLWPEDETEKEEGEEVEEPAASPQEEEPEAGVQPEQEPSQLSILRTYIKTQVNKELEQLQKLVEERLKASEERLSSKLTALERPLQPPPGKGKNKTK", "length": 336 }, "evidence": [ { "id": "A0A061I8E0", "url": "https://omabrowser.org/oma/group/A0A061I8E0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6NZQ0-1", "protein_name": "Cilia- and flagella-associated protein 119", "gene_name": "Cfap119", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MITPSSSQSLGMKVQMESEQSPKLQEELDRSPSSVDGSAIRNGTDMQTESPAEATSSPVEVAEDPGANLFPPPLPQPRICMWKYLDIHSMHRLEKAATVEKMREVLAELLELGFPEQSLRDAIILDLFSHALIFCRQQGFSPEQTSAACAMLQDLHKACVATPLGNVEECYRYFTSVLFCHGIRRPPFSIDLFKEEQLLALADYVVNTYFRHFKLYKYVFTPQVRLDLSLTYTGLQPLTLWPEEKENEEMMVVEQVATPQEEEPETVTEPEQQPSEVCILQTYIKSQLSKELRQLQQLVEERLKESEERLSSKLAALEQPFQTPPSKGKTKTK", "length": 333 }, "evidence": [ { "id": "A0A061I8E0", "url": "https://omabrowser.org/oma/group/A0A061I8E0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "U3JAD7-1", "protein_name": "Cilia- and flagella-associated protein 119 isoform 1", "gene_name": "cfap119", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": 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This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027287750", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287750" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LEQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEQ7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Slc25a43", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEQ7", "locus": {} } ], "crossref": [ { "id": "100769378", "url": "https://www.ncbi.nlm.nih.gov/gene/100769378", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002067", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002067", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769378", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769378", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LEQ7", "url": "https://www.orthodb.org/?gene=A0A8C2LEQ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7K246", "url": "https://www.orthodb.org/?gene=A0A9J7K246", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24089", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24089", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00153", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00153", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027287750", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287750", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LEQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LEQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K246", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K246", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K246-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K246-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATWRRDSRLTGSQRLLCAGLAGVFSLSLTAPLELATVLAQVGMVQGHTQGLWATGRRVWLAEGPRALWKGNGVACLRLFPCSMVQLAAYRKFVVLFMDDLGHISQWHSIVAGSLAGMVSMIVTYPTDLIKTRLIVQNMLKPSYRGITHAFSTIYQQEGFLALYRGVSLTVLGAVPFSAGSLLVYMNLEKIWNGPRERFSQLQNFANGCMAAAVSQSLSFPFDTVKRKMQAQSPYLPNCGGVDVHFSGAVDCFRQIVKTQGALGLWSGLTANLLKVVPYFGVMFSMFEFCKRIFLYQNGYILSPLTYKLTPGVDQSLKPQELRELKKFFKPRTGI", "length": 335, "header": "tr|A0A8C2LEQ7-1|A0A8C2LEQ7_CRIGR Isoform 1 of Solute carrier family 25 member 43 OS=Cricetulus griseus OX=10029 GN=Slc25a43 PE=3 SV=1 CANONICAL=A0A8C2LEQ7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LEQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEQ7/entry#A0A8C2LEQ7-1", "sequence": { "sequence": "MATWRRDSRLTGSQRLLCAGLAGVFSLSLTAPLELATVLAQVGMVQGHTQGLWATGRRVWLAEGPRALWKGNGVACLRLFPCSMVQLAAYRKFVVLFMDDLGHISQWHSIVAGSLAGMVSMIVTYPTDLIKTRLIVQNMLKPSYRGITHAFSTIYQQEGFLALYRGVSLTVLGAVPFSAGSLLVYMNLEKIWNGPRERFSQLQNFANGCMAAAVSQSLSFPFDTVKRKMQAQSPYLPNCGGVDVHFSGAVDCFRQIVKTQGALGLWSGLTANLLKVVPYFGVMFSMFEFCKRIFLYQNGYILSPLTYKLTPGVDQSLKPQELRELKKFFKPRTGI", "length": 335, "header": "tr|A0A8C2LEQ7-1|A0A8C2LEQ7_CRIGR Isoform 1 of Solute carrier family 25 member 43 OS=Cricetulus griseus OX=10029 GN=Slc25a43 PE=3 SV=1 CANONICAL=A0A8C2LEQ7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K246-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEQ7/entry#A0A9J7K246-1", "sequence": { "sequence": "MATWRRDSRLTGSQRLLCAGLAGVFSLSLTAPLELATVLAQVGMVQGHTQGLWATGRRVWLAEGPRALWKGNGVACLRLFPCSMVQLAAYRKFVVLFMDDLGHISQWHSIVAGSLAGMVSMIVTYPTDLIKTRLIVQNMLKPSYRGITHAFSTIYQQEGFLALYRGVSLTVLGAVPFSAGSLLVYMNLEKIWNGPRERFSQLQNFANGCMAAAVSQSLSFPFDTVKRKMQARGWKGSKSLSSQLWRSRCPFLRSSGLLPADSEDPRGTRALERTDS", "length": 276, "header": "tr|A0A9J7K246-1|A0A8C2LEQ7_CRIGR Computationally mapped isoform of Solute carrier family 25 member 43 OS=Cricetulus griseus OX=10029 GN=Slc25a43 PE=3 SV=1 CANONICAL=A0A8C2LEQ7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K246", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K246" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K246", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K246" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769378", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769378", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LEQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEQ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LEQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEQ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LCB3-1", "uniprot_ac": "A0A8C2LCB3", "uniprot_id": "A0A8C2LCB3_CRIGR", 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"##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613640.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027242213", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027242213" } ] }, { "annotation": "Catalyzes the phosphorylation of the ketose sugar fructose to fructose-1-phosphate.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7KA63", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KA63#function" }, { "database": "UniProtKB", "id": "ARBA00057271", "url": "https://www.uniprot.org/uniprotkb/ARBA00057271#function" }, { "database": "UniProtKB", "id": "A0A8C2L859", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L859#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LCB3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCB3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Khk", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCB3", "locus": {} } ], "crossref": [ { "id": "cd01939", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01939", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100763359", "url": "https://www.ncbi.nlm.nih.gov/gene/100763359", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002173", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002173", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034093", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034093", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052562", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052562", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763359", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763359", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2L859", "url": "https://www.orthodb.org/?gene=A0A8C2L859", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LCB3", "url": "https://www.orthodb.org/?gene=A0A8C2LCB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JX76", "url": "https://www.orthodb.org/?gene=A0A9J7JX76", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42774", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42774", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42774:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42774:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00294", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00294", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027242213", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027242213", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2L859", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L859", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2L859-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L859-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LCB3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LCB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCB3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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} ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 142 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613595.1) and transcript sequence (IACG01087037.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003495600", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495600" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061I5Y6", "url": "https://www.uniprot.org/uniprotkb/A0A061I5Y6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tmem50b", "url": "https://www.uniprot.org/uniprotkb/A0A061I5Y6", "locus": {} } ], "crossref": [ { "id": "100757829", "url": "https://www.ncbi.nlm.nih.gov/gene/100757829", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007919", "database": "InterPro", "categories": [ "Protein Classification" 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I5Y6-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I5Y6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYF0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYF0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G2W8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2W8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G2W8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2W8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JMX5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JMX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JMX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JMX5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], 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"https://www.uniprot.org/uniprotkb/A0A061I5Y6/entry#A0A9J7JMX5-1", "sequence": { "sequence": "MAGFLDNFRWPECECIDWSERRNAVASVVAGILFFTGWWIMIDAAVVYPKPEQLNHAFHTCGVFSTLAFFMINAVSNAQVRGDSYESGCLGRTGARVWLFIGFMLMFGSLIASMWILFGAYVTQNIDVYPGLAVFFQNALIFFSFVHPL", "length": 149, "header": "tr|A0A9J7JMX5-1|A0A9J7JMX5_CRIGR Computationally mapped isoform of Transmembrane protein 50B isoform X4 OS=Cricetulus griseus OX=10029 GN=Tmem50b PE=3 SV=1 CANONICAL=A0A061I5Y6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I5Y6", "url": "https://www.uniprot.org/uniprotkb/A0A061I5Y6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757829", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757829", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1L1RX69-1", "protein_name": "Transmembrane protein 50B", "gene_name": "TMEM50B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGFLDNFRWPECECIDWSERRNAIASIVAGVLFFTGWWIMIDAAVVYPKPEQMNHAFHTCGVFSTLAFFMINAVSNAQVRGDSYSDGCLGRTGARVWLFIGFMLMFGSLIASMWILFGAYVTQNTNVYPGLAVFFQNALIFFSTLIYKFGRTEELWG", "length": 158 }, "evidence": [ { "id": "A0A061I5Y6", "url": "https://omabrowser.org/oma/group/A0A061I5Y6/", "database": "OMA" } ], "glygen_name": "Chicken", 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ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027267994", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267994" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061I5Y7", "url": "https://www.uniprot.org/uniprotkb/A0A061I5Y7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100764447", "url": "https://www.uniprot.org/uniprotkb/A0A061I5Y7", "locus": {} } ], "crossref": [ { "id": "cd15228", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15228", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100764447", "url": "https://www.ncbi.nlm.nih.gov/gene/100764447", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764447", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764447", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061I5Y7", "url": "https://www.orthodb.org/?gene=A0A061I5Y7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027267994", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267994", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061I5Y7", "url": "https://www.uniprot.org/uniprotkb/A0A061I5Y7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I5Y7-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I5Y7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDMRNCSVVTEFILLGIPHTEGLETMLFVLFLPFYACTLVGNVSILVAVISSTRLHTPMYFFLGNLSIFDMGFSSVTCPKMLLYLMGLSRLISYQDCVSQLFFFHFLGSIECFLYTVMAYDRFAAICHPLRYSVIMNSRICVALAVGTWLLGCLHSSILTSLTFTLPYCGPNKVDYFFCDIPAVLPLASADTSLAKRVSFTNVGLVSLVCFLLILVSYTRIAISILSIHSTEGRQRAFSTCSAHLIAILCAYGPIITVYLQPTPNPMLGTVVQILMNLVGPMLNPLIYTLRNKEVKIALKKVVHGKGHFSED", "length": 312, "header": "tr|A0A061I5Y7-1|A0A061I5Y7_CRIGR Isoform 1 of Olfactory receptor 958 OS=Cricetulus griseus OX=10029 GN=LOC100764447 PE=3 SV=1 CANONICAL=A0A061I5Y7-1" }, "isoforms": [ { "isoform_ac": "A0A061I5Y7-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I5Y7/entry#A0A061I5Y7-1", "sequence": { "sequence": "MDMRNCSVVTEFILLGIPHTEGLETMLFVLFLPFYACTLVGNVSILVAVISSTRLHTPMYFFLGNLSIFDMGFSSVTCPKMLLYLMGLSRLISYQDCVSQLFFFHFLGSIECFLYTVMAYDRFAAICHPLRYSVIMNSRICVALAVGTWLLGCLHSSILTSLTFTLPYCGPNKVDYFFCDIPAVLPLASADTSLAKRVSFTNVGLVSLVCFLLILVSYTRIAISILSIHSTEGRQRAFSTCSAHLIAILCAYGPIITVYLQPTPNPMLGTVVQILMNLVGPMLNPLIYTLRNKEVKIALKKVVHGKGHFSED", "length": 312, "header": "tr|A0A061I5Y7-1|A0A061I5Y7_CRIGR Isoform 1 of Olfactory receptor 958 OS=Cricetulus griseus OX=10029 GN=LOC100764447 PE=3 SV=1 CANONICAL=A0A061I5Y7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I5Y7", "url": "https://www.uniprot.org/uniprotkb/A0A061I5Y7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"UniProtKB", "id": "A0A061I5Y7", "url": "https://www.uniprot.org/uniprotkb/A0A061I5Y7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A061I5Y7", "url": "https://www.uniprot.org/uniprotkb/A0A061I5Y7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061I5Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I5Y7" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 288, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 42, "end_pos": 44 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614420.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003507804", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507804" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061I619", "url": "https://www.uniprot.org/uniprotkb/A0A061I619" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100771214", "url": "https://www.uniprot.org/uniprotkb/A0A061I619", "locus": {} } ], "crossref": [ { "id": "100771214", "url": "https://www.ncbi.nlm.nih.gov/gene/100771214", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008733", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008733", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026510", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026510", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771214", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771214", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PIEKICW", "url": "https://omabrowser.org/oma/group/PIEKICW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061I619", "url": "https://www.orthodb.org/?gene=A0A061I619", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FYV8", "url": "https://www.orthodb.org/?gene=A0A9J7FYV8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20990", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20990", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20990:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20990:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05648", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003507804", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507804", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061I619", "url": "https://www.uniprot.org/uniprotkb/A0A061I619", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I619-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I619-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYV8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYV8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALLNSLASSLESYRGRDRLIRTLGYCCQLVGGVLVEQCPSRSEMGRRLLVVSAQLSHCRTVLRLFDDPAMFVYTKQYGLGTEEEDIFIRLLSVLSNMADQLYYPCEHVAWAADAKVLQVDAARWWTLSTALWILSLLLGVVRSLWTALKLRQMLRSPTGAFTSQLPRSKRRAMEARMWSEVLTLLSNLADLANAVHWLPRGVLWAGHFPPWLVGLMGTISSLLSMYQAARAGGTAEADSS", "length": 241, "header": "tr|A0A061I619-1|A0A061I619_CRIGR Isoform 1 of Peroxisomal membrane protein 11C isoform X4 OS=Cricetulus griseus OX=10029 GN=LOC100771214 PE=4 SV=1 CANONICAL=A0A061I619-1" }, "isoforms": [ { "isoform_ac": "A0A061I619-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I619/entry#A0A061I619-1", "sequence": { "sequence": "MALLNSLASSLESYRGRDRLIRTLGYCCQLVGGVLVEQCPSRSEMGRRLLVVSAQLSHCRTVLRLFDDPAMFVYTKQYGLGTEEEDIFIRLLSVLSNMADQLYYPCEHVAWAADAKVLQVDAARWWTLSTALWILSLLLGVVRSLWTALKLRQMLRSPTGAFTSQLPRSKRRAMEARMWSEVLTLLSNLADLANAVHWLPRGVLWAGHFPPWLVGLMGTISSLLSMYQAARAGGTAEADSS", "length": 241, "header": "tr|A0A061I619-1|A0A061I619_CRIGR Isoform 1 of Peroxisomal membrane protein 11C isoform X4 OS=Cricetulus griseus OX=10029 GN=LOC100771214 PE=4 SV=1 CANONICAL=A0A061I619-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FYV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I619/entry#A0A9J7FYV8-1", "sequence": { "sequence": "MGRRLLVVSAQLSHCRTVLRLFDDPAMFVYTKQYGLGTEEEDIFIRLLSVLSNMADQLYYPCEHVAWAADAKVLQVDAARWWTLSTALWILSLLLGVVRSLWTALKLRQMLRSPTGAFTSQLPRSKRRAMEARMWSEVLTLLSNLADLANAVHWLPRGVLWAGHFPPWLVGLMGTISSLLSMYQAARAGGTAEADSS", "length": 197, "header": "tr|A0A9J7FYV8-1|A0A9J7FYV8_CRIGR Computationally mapped isoform of Peroxisomal membrane protein 11C isoform X5 OS=Cricetulus griseus OX=10029 GN=LOC100771214 PE=4 SV=1 CANONICAL=A0A061I619-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I619", "url": "https://www.uniprot.org/uniprotkb/A0A061I619" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_003614197.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003505952.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003505952", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505952" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061I6E5", "url": "https://www.uniprot.org/uniprotkb/A0A061I6E5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Efcab1", "url": "https://www.uniprot.org/uniprotkb/A0A061I6E5", "locus": {} } ], "crossref": [ { "id": "cd00051", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00051", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100768257", "url": "https://www.ncbi.nlm.nih.gov/gene/100768257", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768257", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768257", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DNDGCVS", "url": "https://omabrowser.org/oma/group/DNDGCVS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061I6E5", "url": "https://www.orthodb.org/?gene=A0A061I6E5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23055", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23055", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23055:SF75", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23055:SF75", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13833", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13833", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003505952", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505952", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061I6E5", "url": "https://www.uniprot.org/uniprotkb/A0A061I6E5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I6E5-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I6E5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1D5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1D5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1D5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1D5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNRKKLQKLTDTLTKSCKHFNKYEVNCLITLFYNLVGDAAERSGAVVGLDRNAFRNILHVTFRMTDDMIMDRVFRGFDRDNDGCVNVSEWVQGLSLFLRGTLEEKMKYCFEVFDLNGDGFISKEEMFHMLKNSLLKQPSEEDPDEGIKDLVEITLKKMDQDHDGKLSYTDYENAVREETLLLEAFGPCLPDPKSQMEFEAQVFKDPHEFHDI", "length": 212, "header": "tr|A0A061I6E5-1|A0A061I6E5_CRIGR Isoform 1 of EF-hand calcium-binding domain-containing protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Efcab1 PE=4 SV=1 CANONICAL=A0A061I6E5-1" }, "isoforms": [ { "isoform_ac": "A0A061I6E5-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I6E5/entry#A0A061I6E5-1", "sequence": { "sequence": "MNRKKLQKLTDTLTKSCKHFNKYEVNCLITLFYNLVGDAAERSGAVVGLDRNAFRNILHVTFRMTDDMIMDRVFRGFDRDNDGCVNVSEWVQGLSLFLRGTLEEKMKYCFEVFDLNGDGFISKEEMFHMLKNSLLKQPSEEDPDEGIKDLVEITLKKMDQDHDGKLSYTDYENAVREETLLLEAFGPCLPDPKSQMEFEAQVFKDPHEFHDI", "length": 212, "header": "tr|A0A061I6E5-1|A0A061I6E5_CRIGR Isoform 1 of EF-hand calcium-binding domain-containing protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Efcab1 PE=4 SV=1 CANONICAL=A0A061I6E5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H1D5-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I6E5/entry#A0A9J7H1D5-1", "sequence": { "sequence": "MNRKKLQKLTDTLTKSCKHLFRGFDRDNDGCVNVSEWVQGLSLFLRGTLEEKMKYCFEVFDLNGDGFISKEEMFHMLKNSLLKQPSEEDPDEGIKDLVEITLKKMDQDHDGKLSYTDYENAVREETLLLEAFGPCLPDPKSQMEFEAQVFKDPHEFHDI", "length": 159, "header": "tr|A0A9J7H1D5-1|A0A9J7H1D5_CRIGR Computationally mapped isoform of EF-hand calcium-binding domain-containing protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Efcab1 PE=4 SV=1 CANONICAL=A0A061I6E5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I6E5", "url": "https://www.uniprot.org/uniprotkb/A0A061I6E5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I6E5", "url": "https://www.uniprot.org/uniprotkb/A0A061I6E5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768257", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768257", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BPF8-1", "protein_name": "Calaxin", "gene_name": "CLXN", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNRKKLQKLTESLTKDCKHFNKFEVKCLISLFYNLVGDVTERQGVVVGLDRNAFRNILHVTFGMTDDMIMDRVFRGFDKDNDGCVSVSEWVYGLSVFLRGTLEEKMKYCFEVFDLNGDGFISKEEMVHMLKNSLLKQPSEEDPDEGIKDLVEITLKKMDHDHDGKLSFPDYEAAVREEALLLEAFGPCLPDPKSQKEFEAQVFKDPNEFGEV", "length": 212 }, "evidence": [ { "id": "A0A061I6E5", "url": "https://omabrowser.org/oma/group/A0A061I6E5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0KYW5-1", "protein_name": "Calaxin", "gene_name": "Clxn", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNRKKLQKLTDTLTKSCKHFNKFEVKCLITLFYNLVGDVPEKPGVVTGLDRNVFRNILHVTFGMTDDMIMDRVFRGFDRDNDGCISVSEWVHGLSLFLRGTLDEKMKYCFEVFDLNGDGFISKEEMFHMLKNSLLKQPSEEDPDEGIKDLVEITLKKMDHDHDGKLSFVDYETAVREETLLLEAFGPCLPDPKWWPASSNFSNRRASFCFFLHSELLL", "length": 218 }, "evidence": [ { "id": "A0A061I6E5", "url": "https://omabrowser.org/oma/group/A0A061I6E5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q32L26-1", "protein_name": "Calaxin", "gene_name": "CLXN", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNRKKLQKLTDSLTKNCKHFSKFEVKCLINLFYNLVGEVTERQGVIIGLDRNAFRNILHMTFGMTDDMIMDRVFRGFDKDNDGCISVTEWVYGLSVFLRGTLEEKMKYCFEVFDLNGDSFISKEEMFHMLKNSLLKQPSEEDPDEGIKDLVEITLKKMDHDHDGKLSFADYEQAVREETLLLEAFGPCLPDPKSQSEFEAQVFKDPNEFNEV", "length": 212 }, "evidence": [ { "id": "A0A061I6E5", "url": "https://omabrowser.org/oma/group/A0A061I6E5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9D3N2-1", "protein_name": "Calaxin", "gene_name": "Clxn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNRKKLQKLTDTLTKNCKHFDKFEVKCLITLFYNLVGDVAERPGVVTGLDRNVFRNILHVTFGMTDDMIMDRVFRGFDKDNDGCISVSEWIHGLSLFLRGTLDEKMKYCFEVFDLNGDGFISKEEMFHMLKNSLLKQPSEEDPDEGIKDLVEITLKKMDHDHDGKLSFVDYEKAVREENLLLEAFGPCLPDPKSQMEFEAQVFKDPNEFNDM", "length": 212 }, "evidence": [ { "id": "A0A061I6E5", "url": "https://omabrowser.org/oma/group/A0A061I6E5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HAE3-1", "protein_name": "Calaxin", "gene_name": "CLXN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNRKKLQKLTDTLTKNCKHFNKFEVNCLIKLFYDLVGGVERQGLVVGLDRNAFRNILHVTFGMTDDMIMDRVFRGFDKDNDGCVNVLEWIHGLSLFLRGSLEEKMKYCFEVFDLNGDGFISKEEMFHMLKNSLLKQPSEEDPDEGIKDLVEITLKKMDHDHDGKLSFADYELAVREETLLLEAFGPCLPDPKSQMEFEAQVFKDPNEFNDM", "length": 211 }, "evidence": [ { "id": "A0A061I6E5", "url": "https://omabrowser.org/oma/group/A0A061I6E5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VI39-1", "protein_name": "EF-hand domain-containing protein", "gene_name": "Dmel\\CG15177", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MENLDSTVDSTENSKFSALYGGLIKEIAATSKMSTLDITCLLCVYYKFVRFNGPGAKQMKKNQFYQIYLVLFNVANVQVIERSLLAITKDTKYVSPRAWVDLFELYTTEDLERRMKFAFEVYDTKNTGVIDREQVGVACEKFFHEGDDEDELIELRADMTEFIMKKFDVDKDGVISFEDYSSVVSQQPVLVEFLGWLFPSNEERDLMAHVINMDSMLNYCNPDAK", "length": 225 }, "evidence": [ { "id": "A0A061I6E5", "url": "https://omabrowser.org/oma/group/A0A061I6E5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A061I6E5", "url": "https://www.uniprot.org/uniprotkb/A0A061I6E5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "sperm flagellum", "id": "GO:0036126", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036126", "evidence": [ { "database": "UniProtKB", "id": "A0A061I6E5", "url": "https://www.uniprot.org/uniprotkb/A0A061I6E5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of flagellated sperm motility", "id": "GO:1901317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901317", "evidence": [ { "database": "UniProtKB", "id": "A0A061I6E5", "url": "https://www.uniprot.org/uniprotkb/A0A061I6E5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 86, "end_pos": 88, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061I6E5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I6E5" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 65, "end_pos": 100, "start_aa": "Thr", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 86, "end_pos": 88 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061I6K6-1", "uniprot_ac": "A0A061I6K6", "uniprot_id": "A0A061I6K6_CRIGR", "mass": { "chemical_mass": 36957.0, "monoisotopic_mass": 36957.0 }, "refseq": { "ac": "XP_027263796", "name": "olfactory receptor 52D1-like isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263796" }, "gene_names": [ { "name": "LOC100761788", "type": "recommended", "evidence": [ { "id": "A0A061I6K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I6K6" } ] }, { "name": "LOC100761788", "type": "synonym", "evidence": [ { "id": "XP_027263796", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263796" } ] } ], "protein_names": [ { "name": "Olfactory receptor 52D1-like isoform X2", "type": "synonym", "evidence": [ { "id": "A0A061I6K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I6K6/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 52D1-like isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027263796", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263796" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. 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Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613616.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003496292", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496292" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061I7H1", "url": "https://www.uniprot.org/uniprotkb/A0A061I7H1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Yae1", "url": "https://www.uniprot.org/uniprotkb/A0A061I7H1", "locus": {} } ], "crossref": [ { "id": "100769054", "url": "https://www.ncbi.nlm.nih.gov/gene/100769054", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019191", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019191", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769054", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769054", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VKKQTVW", "url": "https://omabrowser.org/oma/group/VKKQTVW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061I7H1", "url": "https://www.orthodb.org/?gene=A0A061I7H1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18829", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18829", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18829:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18829:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09811", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09811", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003496292", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496292", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061I7H1", "url": "https://www.uniprot.org/uniprotkb/A0A061I7H1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I7H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I7H1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSWVRAVPEIPSSGDQDVFDEEADETLLVQREWQGHMRRRIQEGYRDGIDAGKAVTLQQGFNQGYKEGAEVIINYGLLRGTLSALLSWCHLHGNSSTLVSKINNLLDAVGQCEECVLKRLKSVAPQPQVTDLLDSIEDMDLCHVVPAEKKIDEVKDERLCENSAEFNKNSDKSHIRTDCSHSECCRTQEHEHLEKPSLTWILEQTASLVKQLGVSVDVLQHLRQL", "length": 225, "header": "tr|A0A061I7H1-1|A0A061I7H1_CRIGR Isoform 1 of Protein YAE1 homolog OS=Cricetulus griseus OX=10029 GN=Yae1 PE=4 SV=1 CANONICAL=A0A061I7H1-1" }, "isoforms": [ { "isoform_ac": "A0A061I7H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I7H1/entry#A0A061I7H1-1", "sequence": { "sequence": "MSWVRAVPEIPSSGDQDVFDEEADETLLVQREWQGHMRRRIQEGYRDGIDAGKAVTLQQGFNQGYKEGAEVIINYGLLRGTLSALLSWCHLHGNSSTLVSKINNLLDAVGQCEECVLKRLKSVAPQPQVTDLLDSIEDMDLCHVVPAEKKIDEVKDERLCENSAEFNKNSDKSHIRTDCSHSECCRTQEHEHLEKPSLTWILEQTASLVKQLGVSVDVLQHLRQL", "length": 225, "header": "tr|A0A061I7H1-1|A0A061I7H1_CRIGR Isoform 1 of Protein YAE1 homolog OS=Cricetulus griseus OX=10029 GN=Yae1 PE=4 SV=1 CANONICAL=A0A061I7H1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"monoisotopic_mass": 51079.0 }, "refseq": { "ac": "XP_016822355", "name": "protein phosphatase 1M isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016822355" }, "gene_names": [ { "name": "Ppm1m", "type": "recommended", "evidence": [ { "id": "A0A061I809", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I809" } ] }, { "name": "Ppm1m", "type": "synonym", "evidence": [ { "id": "XP_016822355", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016822355" } ] } ], "protein_names": [ { "name": "Protein phosphatase 1M isoform X2", "type": "synonym", "evidence": [ { "id": "A0A061I809", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I809/entry#names_and_taxonomy" } ] }, { "name": "protein phosphatase 1M isoform X1", "type": "synonym", "evidence": [ { "id": "XP_016822355", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016822355" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 184 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613657.1) and transcript sequence (IACG01201535.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_016822355.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016822355", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016822355" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061I809", "url": "https://www.uniprot.org/uniprotkb/A0A061I809" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ppm1m", "url": "https://www.uniprot.org/uniprotkb/A0A061I809", "locus": {} } ], "crossref": [ { "id": "cd00143", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00143", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100770979", "url": "https://www.ncbi.nlm.nih.gov/gene/100770979", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001932", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001932", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015655", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015655", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770979", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770979", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061I809", "url": "https://www.orthodb.org/?gene=A0A061I809", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13832", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13832", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13832:SF236", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13832:SF236", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00481", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00481", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016822355", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016822355", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061I809", "url": "https://www.uniprot.org/uniprotkb/A0A061I809", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I809-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I809-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWS4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWS4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWX9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FWX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FWX9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JM30", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JM30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JM30-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JM30-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAGWFRRRFLPGGPLPEPRPAGPRSSPVPYHRPRFLRGSGSSPSATDASRRPDSRPVRSPARGRTLPWNAGYAEIINAEKSEFNEDQAACGKLCIRRCLFGIAEDQEWLTVCPEEFLTGHYWALFDGHGGPAAAILAANTLHSCLRRQLEAVVEGMVATQPPMHLSGRCVCSSDPHFVEEKGIRAEDLVIGALESAFQECDDVIGRELEASGQVGGCTALVAVSLQGKLYVANAGDSRAILVRRDEIRVLSTEFTPETERQRIQQLAFIYPELLAGEFTRLEFPRRLKGDDLGEKVLFRDHHMNGWSYKQVEKSDLKYPLIHGQGRQARLLGTLAVSRGLGDHQLRVLDTNIQLKPFLLSIPQVTVLDVDQLALEEEDVVIMATDGLWDVLSNEQVARLVRRFLTGNREDPHRFSELAKMLIHNTQGKDDGATGEGQVSYDDVSVFVIPLHSQDKGNSGQ", "length": 461, "header": "tr|A0A061I809-1|A0A061I809_CRIGR Isoform 1 of Protein phosphatase 1M isoform X2 OS=Cricetulus griseus OX=10029 GN=Ppm1m PE=4 SV=1 CANONICAL=A0A061I809-1" }, "isoforms": [ { "isoform_ac": "A0A061I809-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I809/entry#A0A061I809-1", "sequence": { "sequence": "MSAGWFRRRFLPGGPLPEPRPAGPRSSPVPYHRPRFLRGSGSSPSATDASRRPDSRPVRSPARGRTLPWNAGYAEIINAEKSEFNEDQAACGKLCIRRCLFGIAEDQEWLTVCPEEFLTGHYWALFDGHGGPAAAILAANTLHSCLRRQLEAVVEGMVATQPPMHLSGRCVCSSDPHFVEEKGIRAEDLVIGALESAFQECDDVIGRELEASGQVGGCTALVAVSLQGKLYVANAGDSRAILVRRDEIRVLSTEFTPETERQRIQQLAFIYPELLAGEFTRLEFPRRLKGDDLGEKVLFRDHHMNGWSYKQVEKSDLKYPLIHGQGRQARLLGTLAVSRGLGDHQLRVLDTNIQLKPFLLSIPQVTVLDVDQLALEEEDVVIMATDGLWDVLSNEQVARLVRRFLTGNREDPHRFSELAKMLIHNTQGKDDGATGEGQVSYDDVSVFVIPLHSQDKGNSGQ", "length": 461, "header": "tr|A0A061I809-1|A0A061I809_CRIGR Isoform 1 of Protein phosphatase 1M isoform X2 OS=Cricetulus griseus OX=10029 GN=Ppm1m PE=4 SV=1 CANONICAL=A0A061I809-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FWS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I809/entry#A0A9J7FWS4-1", "sequence": { "sequence": "MSAGWFRRRFLPGGPLPEPRPAGPRSSPVPYHRPRFLRGSGSSPSATDASRRPDSRPVRSPARGRTLPWNAGYAEIINAEKSEFNEDQAACGKLCIRRCLFGIAEDQEWLTVCPEEFLTGHYWALFDGHGGPAAAILAANTLHSCLRRQLEAVVEGMVATQPPMHLSGRCVCSSDPHFVEEKGIRAEDLVIGALESAFQECDDVIGRELEASGQVGGCTALVAVSLQGKLYVANAGDSRAILVRRDEIRVLSTEFTPETERQRIQQLLLAGEFTRLEFPRRLKGDDLGEKVLFRDHHMNGWSYKQVEKSDLKYPLIHGQGRQARLLGTLAVSRGLGDHQLRVLDTNIQLKPFLLSIPQVTVLDVDQLALEEEDVVIMATDGLWDVLSNEQVARLVRRFLTGNREDPHRFSELAKMLIHNTQGKDDGATGEGQVSYDDVSVFVIPLHSQDKGNSGQ", "length": 455, "header": "tr|A0A9J7FWS4-1|A0A9J7FWS4_CRIGR Computationally mapped isoform of Protein phosphatase 1M isoform X3 OS=Cricetulus griseus OX=10029 GN=Ppm1m PE=4 SV=1 CANONICAL=A0A061I809-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FWX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I809/entry#A0A9J7FWX9-1", "sequence": { "sequence": "MSAGWFRRRFLPGGPLPEPRPAGPRSSPVPYHRPRFLRGSGSSPSATDASRRPDSRPVRSPARGRTLPWNAGYAEIINAEKSEFNEDQAACGKLCIRRCLFGIAEDQEWLTVCPEEFLTGHYWALFDGHGGPAAAILAANTLHSCLRRQLEAVVEGMVATQPPMHLSGRCVCSSDPHFVEEKGIRAEDLVIGALESAFQECDDVIGRELEASGQVGGCTALVAVSLQGKLYVANAGDSRAILVRRDEIRVLSTEFTPETERQRIQQLAFIYPELLAGEFTRLEFPRRLKGDDLGEKVLFRDHHMNGWSYKQVEKSDLKYPLIHGQGRQVTVLDVDQLALEEEDVVIMATDGLWDVLSNEQVARLVRRFLTGNREDPHRFSELAKMLIHNTQGKDDGATGEGQVSYDDVSVFVIPLHSQDKGNSGQ", "length": 425, "header": "tr|A0A9J7FWX9-1|A0A9J7FWX9_CRIGR Computationally mapped isoform of Protein phosphatase 1M isoform X5 OS=Cricetulus griseus OX=10029 GN=Ppm1m PE=4 SV=1 CANONICAL=A0A061I809-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JM30-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I809/entry#A0A9J7JM30-1", "sequence": { "sequence": "MSAGWFRRRFLPGGPLPEPRPAGPRSSPVPYHRPRFLRGSGSSPSATDASRRPDSRPVRSPARGRTLPWNAGYAEIINAEKSEFNEDQAACGKLCIRRCLFGIAEDQEWLTVCPEEFLTGHYWALFDGHGGPAAAILAANTLHSCLRRQLEAVVEGMVATQPPMHLSGRCVCSSDPHFVEEKGIRAEDLVIGALESAFQECDDVIGRELEASGQVGGCTALVAVSLQGKLYVANAGDSRAILVRRDEIRVLSTEFTPETERQRIQQLAFIYPELLAGEFTRLEFPRRLKGDDLGEKVLFRDHHMNGWSYKQVEKSDLKYPLIHGQGRQARLLGTLAVSRGLGDHQLRVLDTNIQLKPFLLSIPQLALEEEDVVIMATDGLWDVLSNEQVARLVRRFLTGNREDPHRFSELAKMLIHNTQGKDDGATGEGQVSYDDVSVFVIPLHSQDKGNSGQ", "length": 453, "header": "tr|A0A9J7JM30-1|A0A9J7JM30_CRIGR Computationally mapped isoform of Protein phosphatase 1M isoform X4 OS=Cricetulus griseus OX=10029 GN=Ppm1m PE=4 SV=1 CANONICAL=A0A061I809-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I809", "url": "https://www.uniprot.org/uniprotkb/A0A061I809" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I809", "url": "https://www.uniprot.org/uniprotkb/A0A061I809" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770979", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770979", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "[pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity", "id": "GO:0004741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004741", "evidence": [ { "database": "UniProtKB", "id": "A0A061I809", "url": "https://www.uniprot.org/uniprotkb/A0A061I809" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A061I809", "url": "https://www.uniprot.org/uniprotkb/A0A061I809" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061I809", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I809" }, { "id": "PS51746", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51746" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PPM-type phosphatase", "eco_id": "ECO_0000259", "start_pos": 100, "end_pos": 451, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613582.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007645144", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645144" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061I8S9", "url": "https://www.uniprot.org/uniprotkb/A0A061I8S9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "C4H15orf65", "url": "https://www.uniprot.org/uniprotkb/A0A061I8S9", "locus": {} } ], "crossref": [ { "id": "100768761", "url": "https://www.ncbi.nlm.nih.gov/gene/100768761", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026507", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026507", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A061I8S9", "url": "https://www.orthodb.org/?gene=A0A061I8S9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20899", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20899", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20899:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20899:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14892", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14892", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007645144", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645144", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061I8S9", "url": "https://www.uniprot.org/uniprotkb/A0A061I8S9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I8S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I8S9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKPEPSAPCVNPGNPVFSCMLDPKTFHTTTSLSKPQMIMYKTNSSQYGAFSPKPQFFPCRYTPKEQVFSNHIKATGFYQNNSLNTAPDRTRTIDFPNFQHTL", "length": 102, "header": "tr|A0A061I8S9-1|A0A061I8S9_CRIGR Isoform 1 of Uncharacterized protein C15orf65 homolog isoform X2 OS=Cricetulus griseus OX=10029 GN=C4H15orf65 PE=4 SV=1 CANONICAL=A0A061I8S9-1" }, "isoforms": [ { "isoform_ac": "A0A061I8S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I8S9/entry#A0A061I8S9-1", "sequence": { "sequence": "MKPEPSAPCVNPGNPVFSCMLDPKTFHTTTSLSKPQMIMYKTNSSQYGAFSPKPQFFPCRYTPKEQVFSNHIKATGFYQNNSLNTAPDRTRTIDFPNFQHTL", "length": 102, "header": "tr|A0A061I8S9-1|A0A061I8S9_CRIGR Isoform 1 of Uncharacterized protein C15orf65 homolog isoform X2 OS=Cricetulus griseus OX=10029 GN=C4H15orf65 PE=4 SV=1 CANONICAL=A0A061I8S9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613865.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007640748", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640748" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061I993", "url": "https://www.uniprot.org/uniprotkb/A0A061I993" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "CUNH19orf67", "url": "https://www.uniprot.org/uniprotkb/A0A061I993", "locus": {} } ], "crossref": [ { "id": "100768711", "url": "https://www.ncbi.nlm.nih.gov/gene/100768711", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR021748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768711", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768711", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WHLETIP", "url": "https://omabrowser.org/oma/group/WHLETIP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061I993", "url": "https://www.orthodb.org/?gene=A0A061I993", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR36292", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36292", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR36292:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36292:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11771", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11771", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007640748", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640748", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061I993", "url": "https://www.uniprot.org/uniprotkb/A0A061I993", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I993-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I993-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAEPWFAGSLALGPGEALPSEELGPGPPPYGDSSWSPAGRPETSAEQEAQRAQQLMEAPASASSREPLAAELGPAQARLPLDSMFSPITDQLRYLLRKADDFQSYLLYSRDRVQKEQLAKAMPTFLTMCEPYFLYLEAAARSVPPIYGALQELVRKGLLEISQQLTLRLEQLVLMYASFGFVDLEETNPLSISCFFCGRFSISPSHDVSIFRYCTPAAYTASHFPRYLYKKMRWNLETTTEASSQGPDSRVDYYFLCYRDTWEDTGQGPANSCPQIQKLWSIGRWLPLGPAEDDLDSWILCPQPPGDYQQLLTIGFEEPSHVLATDLLVQILMGQVGPARPPSTAGPLAWAAPAS", "length": 356, "header": "tr|A0A061I993-1|A0A061I993_CRIGR Isoform 1 of UPF0575 protein C19orf67 homolog OS=Cricetulus griseus OX=10029 GN=CUNH19orf67 PE=4 SV=1 CANONICAL=A0A061I993-1" }, "isoforms": [ { "isoform_ac": "A0A061I993-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I993/entry#A0A061I993-1", "sequence": { "sequence": "MAAEPWFAGSLALGPGEALPSEELGPGPPPYGDSSWSPAGRPETSAEQEAQRAQQLMEAPASASSREPLAAELGPAQARLPLDSMFSPITDQLRYLLRKADDFQSYLLYSRDRVQKEQLAKAMPTFLTMCEPYFLYLEAAARSVPPIYGALQELVRKGLLEISQQLTLRLEQLVLMYASFGFVDLEETNPLSISCFFCGRFSISPSHDVSIFRYCTPAAYTASHFPRYLYKKMRWNLETTTEASSQGPDSRVDYYFLCYRDTWEDTGQGPANSCPQIQKLWSIGRWLPLGPAEDDLDSWILCPQPPGDYQQLLTIGFEEPSHVLATDLLVQILMGQVGPARPPSTAGPLAWAAPAS", "length": 356, "header": "tr|A0A061I993-1|A0A061I993_CRIGR Isoform 1 of UPF0575 protein C19orf67 homolog OS=Cricetulus griseus OX=10029 GN=CUNH19orf67 PE=4 SV=1 CANONICAL=A0A061I993-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I993", "url": "https://www.uniprot.org/uniprotkb/A0A061I993" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I993", "url": "https://www.uniprot.org/uniprotkb/A0A061I993" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768711", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768711", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A6NJJ6-1", "protein_name": "UPF0575 protein C19orf67", "gene_name": "C19orf67", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"MAAESWFAGSLALGPGEAPPSEELGPGPQPYGDPSWSPAGRPEGSTELEPQRAQSMMEAPTSTSSREPLAAELGAAPARLPLDSMFSPITDQLRYLLRKADDFQSYLLYRDRVQKEQLAKAMPTFLTMCEPYFLYLEAAARSVPPIYGALQELVRKGLLEISQQLTLRLEQLVLMYASFGFVDLEETNPLSISCFFCGRFSISPSHDVSIFRYCTPAAYTASHFPRYLYKKMRWNLETTTEASSQGADAHVDYYFLCYRDTWEDAGQGPANSCPQIQKLWSIGRWMPLGPAEDDLDSWILCPQPPGDYQQLLTIGFEEPSHVLATDLLVQILMGQAGPARPPSSAGPAAWAAPAS", "length": 355 }, "evidence": [ { "id": "A0A061I993", "url": "https://omabrowser.org/oma/group/A0A061I993/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CF25-1", "protein_name": "UPF0575 protein C19orf67 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMEAPASTSSREPLAAELGPAPARLPLDSMFSPITDQLRYLLRKADDFQSYLLYSRDRVQKEQLAKAMPTFLTMCEPYFLYLEAAARSVPPIYGALQELVRKGLLEISQQLTLRLEQLVLMYASFGFVDLEETNPLSISCFFCGRFSISPSHDVSIFRYCTPAAYTASHFPRYLYKKMRWNLETTTEASSQGADSHVDYYFLCYRDTWEDAGQGPANSCPQIQKLWSIGRWMPLGPAEDDLDSWILCPQPPGDYQQLLTIGFEEPSHVLATDLLVQILLGQAGPARPPSAAGPAAWAAPAS", "length": 301 }, "evidence": [ { "id": "A0A061I993", "url": "https://omabrowser.org/oma/group/A0A061I993/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], 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This record is derived from a genomic sequence (NW_003613612.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003496198", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496198" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061I9B4", "url": "https://www.uniprot.org/uniprotkb/A0A061I9B4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Angptl5", "url": "https://www.uniprot.org/uniprotkb/A0A061I9B4", "locus": {} } ], "crossref": [ { "id": "cd00087", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00087", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100762578", "url": "https://www.ncbi.nlm.nih.gov/gene/100762578", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762578", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762578", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061I9B4", "url": "https://www.orthodb.org/?gene=A0A061I9B4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19143", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19143", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19143:SF185", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19143:SF185", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00147", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00147", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003496198", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496198", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061I9B4", "url": "https://www.uniprot.org/uniprotkb/A0A061I9B4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I9B4-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I9B4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHHFFHRELIFEELFSLVQENMMYLSQASLLFLNVCIFICGEAVQGICVHHSTDPLVGNNVGDKTNLKDESQAVYKEDCKESRDAKTKVTREEKHFMCRNLQNSIVSYTRSTKKLLRNIMDEQQASLDYLSSQVNELMNRILLLTTEVFRKHLAPFPSRPMSHGLDCTDIKDSIGSVTKTPSGLYVIFPEGSSYPFEVICDMDFRGGGWTVIQKRIDGTIDFQRPWCDYLDGFGDLLGEFWLGLKKIFYIVNQKDSSFMLHVALESEDDTLAYASYDNFWLEDEIRFFKIHLGRYSGNAGDAFQGFREEDNQNAMPFSTSDVDNDGCHPACLVNSQSVKSCSHLHNNTGWWFNQCGLTNLNGIHHSRGKLHATGIQWGTWTKNNSVVKIKSVSMKIRRIYNPYFK", "length": 405, "header": "tr|A0A061I9B4-1|A0A061I9B4_CRIGR Isoform 1 of Angiopoietin-related protein 5 OS=Cricetulus griseus OX=10029 GN=Angptl5 PE=4 SV=1 CANONICAL=A0A061I9B4-1" }, "isoforms": [ { "isoform_ac": "A0A061I9B4-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I9B4/entry#A0A061I9B4-1", "sequence": { "sequence": "MHHFFHRELIFEELFSLVQENMMYLSQASLLFLNVCIFICGEAVQGICVHHSTDPLVGNNVGDKTNLKDESQAVYKEDCKESRDAKTKVTREEKHFMCRNLQNSIVSYTRSTKKLLRNIMDEQQASLDYLSSQVNELMNRILLLTTEVFRKHLAPFPSRPMSHGLDCTDIKDSIGSVTKTPSGLYVIFPEGSSYPFEVICDMDFRGGGWTVIQKRIDGTIDFQRPWCDYLDGFGDLLGEFWLGLKKIFYIVNQKDSSFMLHVALESEDDTLAYASYDNFWLEDEIRFFKIHLGRYSGNAGDAFQGFREEDNQNAMPFSTSDVDNDGCHPACLVNSQSVKSCSHLHNNTGWWFNQCGLTNLNGIHHSRGKLHATGIQWGTWTKNNSVVKIKSVSMKIRRIYNPYFK", "length": 405, "header": "tr|A0A061I9B4-1|A0A061I9B4_CRIGR Isoform 1 of Angiopoietin-related protein 5 OS=Cricetulus griseus OX=10029 GN=Angptl5 PE=4 SV=1 CANONICAL=A0A061I9B4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I9B4", "url": "https://www.uniprot.org/uniprotkb/A0A061I9B4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I9B4", "url": "https://www.uniprot.org/uniprotkb/A0A061I9B4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762578", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762578", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A061I9B4", "url": "https://www.uniprot.org/uniprotkb/A0A061I9B4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 346, "end_pos": 348, "annotation": "n_glycosylation_sequon" }, { "start_pos": 383, "end_pos": 385, 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027265847", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265847" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061I9L0", "url": "https://www.uniprot.org/uniprotkb/A0A061I9L0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dennd2b", "url": "https://www.uniprot.org/uniprotkb/A0A061I9L0", "locus": {} } ], "crossref": [ { "id": "100750899", "url": "https://www.ncbi.nlm.nih.gov/gene/100750899", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001194", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001194", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100750899", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750899", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061I9L0", "url": "https://www.orthodb.org/?gene=A0A061I9L0", "database": "OrthoDB", 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genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027265255", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265255" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061I9R7", "url": "https://www.uniprot.org/uniprotkb/A0A061I9R7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100767897", "url": "https://www.uniprot.org/uniprotkb/A0A061I9R7", "locus": {} } ], "crossref": [ { "id": "100767897", "url": "https://www.ncbi.nlm.nih.gov/gene/100767897", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026054", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026054", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767897", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767897", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061I9R7", "url": "https://www.orthodb.org/?gene=A0A061I9R7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23193", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23193", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23193:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23193:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15229", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15229", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027265255", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265255", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061I9R7", "url": "https://www.uniprot.org/uniprotkb/A0A061I9R7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I9R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I9R7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSYLGKAESSPRSPAQGRADAREKPATRRPARPLYQVHRVQHVHRAQPARRHRPARRPPNWDPANPAAFVSEAWRRFPMKRPQNPIMGSLPSDWWESYLKRNIWSLRHPRATWSPVTVKISPPERRPHPLFSASKAVNSAGPSEEPPGGYGKDPVLKALLECRKGRGRWEEPLFPDSSDSKRNSATPWSAFKPLLKSGATVTFVARPGSLKRSLHAQSSDHKRKKSSCSSVAILANICTRGPPSTKRNAITSSYSSSRYLSESWKRHFSRTSVQTPEWPLKKTGKSPISHPLVTPSNSWQPNGEIPPLQSGPSDLLTTPCQQDCVVTEADPTLERQAGPSNQTTEATTATVADAIPETRAGIRPPLSFSPPSSESVLSTHMSPQLESSKNMPVPHGCSQLEHLQGISSDSKPSTASIQVSPSSPTSPVSDSNWPSSVPQAYRKKGLFGRWSWTSETKKAVFSGDKSLL", "length": 469, "header": "tr|A0A061I9R7-1|A0A061I9R7_CRIGR Isoform 1 of POM121-like protein 2 OS=Cricetulus griseus OX=10029 GN=LOC100767897 PE=4 SV=1 CANONICAL=A0A061I9R7-1" }, "isoforms": [ { "isoform_ac": "A0A061I9R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I9R7/entry#A0A061I9R7-1", "sequence": { "sequence": "MGSYLGKAESSPRSPAQGRADAREKPATRRPARPLYQVHRVQHVHRAQPARRHRPARRPPNWDPANPAAFVSEAWRRFPMKRPQNPIMGSLPSDWWESYLKRNIWSLRHPRATWSPVTVKISPPERRPHPLFSASKAVNSAGPSEEPPGGYGKDPVLKALLECRKGRGRWEEPLFPDSSDSKRNSATPWSAFKPLLKSGATVTFVARPGSLKRSLHAQSSDHKRKKSSCSSVAILANICTRGPPSTKRNAITSSYSSSRYLSESWKRHFSRTSVQTPEWPLKKTGKSPISHPLVTPSNSWQPNGEIPPLQSGPSDLLTTPCQQDCVVTEADPTLERQAGPSNQTTEATTATVADAIPETRAGIRPPLSFSPPSSESVLSTHMSPQLESSKNMPVPHGCSQLEHLQGISSDSKPSTASIQVSPSSPTSPVSDSNWPSSVPQAYRKKGLFGRWSWTSETKKAVFSGDKSLL", "length": 469, "header": "tr|A0A061I9R7-1|A0A061I9R7_CRIGR Isoform 1 of POM121-like protein 2 OS=Cricetulus griseus OX=10029 GN=LOC100767897 PE=4 SV=1 CANONICAL=A0A061I9R7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I9R7", "url": "https://www.uniprot.org/uniprotkb/A0A061I9R7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061I9R7", "url": "https://www.uniprot.org/uniprotkb/A0A061I9R7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767897", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767897", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "A0A061I9R7", "url": "https://www.uniprot.org/uniprotkb/A0A061I9R7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "structural constituent of nuclear pore", "id": "GO:0017056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017056", "evidence": [ { "database": "UniProtKB", "id": "A0A061I9R7", "url": "https://www.uniprot.org/uniprotkb/A0A061I9R7" } ], "pmid": "" }, { "name": "nuclear localization sequence binding", "id": "GO:0008139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008139", "evidence": [ { "database": "UniProtKB", "id": "A0A061I9R7", "url": "https://www.uniprot.org/uniprotkb/A0A061I9R7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "RNA export from nucleus", "id": "GO:0006405", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006405", "evidence": [ { "database": "UniProtKB", "id": "A0A061I9R7", "url": "https://www.uniprot.org/uniprotkb/A0A061I9R7" } ], "pmid": "" }, { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "A0A061I9R7", "url": "https://www.uniprot.org/uniprotkb/A0A061I9R7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 342, "end_pos": 344, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 342, "end_pos": 344 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061I9X9-1", "uniprot_ac": "A0A061I9X9", "uniprot_id": "A0A061I9X9_CRIGR", "mass": { "chemical_mass": 97243.0, "monoisotopic_mass": 97243.0 }, "refseq": { "ac": "XP_027260277", "name": "armadillo repeat-containing protein 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260277" }, "gene_names": [ { "name": "Armc5", "type": "recommended", "evidence": [ { "id": "A0A061I9X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9X9" } ] }, { "name": "Armc5", "type": "synonym", "evidence": [ { "id": "XP_027260277", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260277" } ] } ], "protein_names": [ { "name": "Armadillo repeat-containing protein 5", "type": "synonym", "evidence": [ { "id": "A0A061I9X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061I9X9/entry#names_and_taxonomy" } ] }, { "name": "armadillo repeat-containing protein 5", "type": "synonym", "evidence": [ { "id": "XP_027260277", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260277" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027260277", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260277" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061I9X9", "url": "https://www.uniprot.org/uniprotkb/A0A061I9X9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Armc5", "url": "https://www.uniprot.org/uniprotkb/A0A061I9X9", "locus": {} } ], "crossref": [ { "id": "cd18191", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18191", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100772037", "url": "https://www.ncbi.nlm.nih.gov/gene/100772037", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772037", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772037", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061I9X9", "url": "https://www.orthodb.org/?gene=A0A061I9X9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23312", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23312", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23312:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23312:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF24768", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24768", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027260277", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260277", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061I9X9", "url": "https://www.uniprot.org/uniprotkb/A0A061I9X9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I9X9-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I9X9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAARPALTDSLSFCLAQLTAAAGEGPGWGKDPATNETPLGRALLALRTRHIKAADGIERFRARGGLRPLLALLRRTAAAGPAPSHAGSGSAPSSVASAVSSPGPAPAPESPLTPSSPVRLRKTLDLALSILANCCTEEACRAEVRRLGGILPLVTILQCVKIDSIHNRTARALGNLAMEPESCRDIHSAGAVPFLVESLTAYQDSQCLQSIVRALRNLADSPQHRLALAQQGAVRPLAELLATAPDPALTSALVRALLELSRGCSRACAEQLSLGGGLGPLVSLASHPKRPIREAAILILANLCAQGLVRPALGNAGGVEVLLGELRRRRGSSGTSSAAQQPLVRAVCLLCREAINRARLRDAGGLELLMGLLQDPGASAWHPRVVAALVGFLYDTGALGKLQALGLVPLLARQLCGEAGEEEEEGIEAASWDFPEERTPGQTEVGSFRSLRLWLISEGYAAGPGDISPDWSPERCPMPELSESVSPTPGQTAASTPRTLRKLGRIPAATTEEPWGQEGPALLLLSRFSQAPDPSGALVTGPALCGLLAYVTGAPGPPNPRALRILARLTCNPACLEAFVRSYGAALLRAWLILGVSPDDWPVPHARPVHRNQHRELGEMLLQNLTVQAESPFGVGALTHLLLSGSPEDRVACALTLPFICRKPTLWRRLLLDQGGLRHLLTALTQPVPHPLFLFFAADSLSCLHELVSPTVSPILFSVMPSEPDSTSPCLYEPLLGPAPVLAPDLHFVLDSGLQLPAQRAASATASPFFRALLSGSFAEAQMDLVPLRGLSPSAAWPVLHHLHGCRGCGAALGSIPPLGQPLLGSKAEEALEAAGRFLLPALEEELEEAVGRIHLGPQGGPESVGEVFRLGRPRLAAHCVRWTLGPGQCPRKRALALIGLVEAAGEEAGPLTEALLAVLTGIEP", "length": 926, "header": "tr|A0A061I9X9-1|A0A061I9X9_CRIGR Isoform 1 of Armadillo repeat-containing protein 5 OS=Cricetulus griseus OX=10029 GN=Armc5 PE=4 SV=1 CANONICAL=A0A061I9X9-1" }, "isoforms": [ { "isoform_ac": "A0A061I9X9-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I9X9/entry#A0A061I9X9-1", "sequence": { "sequence": "MAAARPALTDSLSFCLAQLTAAAGEGPGWGKDPATNETPLGRALLALRTRHIKAADGIERFRARGGLRPLLALLRRTAAAGPAPSHAGSGSAPSSVASAVSSPGPAPAPESPLTPSSPVRLRKTLDLALSILANCCTEEACRAEVRRLGGILPLVTILQCVKIDSIHNRTARALGNLAMEPESCRDIHSAGAVPFLVESLTAYQDSQCLQSIVRALRNLADSPQHRLALAQQGAVRPLAELLATAPDPALTSALVRALLELSRGCSRACAEQLSLGGGLGPLVSLASHPKRPIREAAILILANLCAQGLVRPALGNAGGVEVLLGELRRRRGSSGTSSAAQQPLVRAVCLLCREAINRARLRDAGGLELLMGLLQDPGASAWHPRVVAALVGFLYDTGALGKLQALGLVPLLARQLCGEAGEEEEEGIEAASWDFPEERTPGQTEVGSFRSLRLWLISEGYAAGPGDISPDWSPERCPMPELSESVSPTPGQTAASTPRTLRKLGRIPAATTEEPWGQEGPALLLLSRFSQAPDPSGALVTGPALCGLLAYVTGAPGPPNPRALRILARLTCNPACLEAFVRSYGAALLRAWLILGVSPDDWPVPHARPVHRNQHRELGEMLLQNLTVQAESPFGVGALTHLLLSGSPEDRVACALTLPFICRKPTLWRRLLLDQGGLRHLLTALTQPVPHPLFLFFAADSLSCLHELVSPTVSPILFSVMPSEPDSTSPCLYEPLLGPAPVLAPDLHFVLDSGLQLPAQRAASATASPFFRALLSGSFAEAQMDLVPLRGLSPSAAWPVLHHLHGCRGCGAALGSIPPLGQPLLGSKAEEALEAAGRFLLPALEEELEEAVGRIHLGPQGGPESVGEVFRLGRPRLAAHCVRWTLGPGQCPRKRALALIGLVEAAGEEAGPLTEALLAVLTGIEP", "length": 926, "header": "tr|A0A061I9X9-1|A0A061I9X9_CRIGR Isoform 1 of Armadillo repeat-containing protein 5 OS=Cricetulus griseus OX=10029 GN=Armc5 PE=4 SV=1 CANONICAL=A0A061I9X9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 489, "start_aa": "Thr", "end_pos": 489, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr489", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027265066", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265066" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IAC9", "url": "https://www.uniprot.org/uniprotkb/A0A061IAC9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pxdc1", "url": "https://www.uniprot.org/uniprotkb/A0A061IAC9", "locus": {} } ], "crossref": [ { "id": "100762877", "url": "https://www.ncbi.nlm.nih.gov/gene/100762877", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040288", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040288", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762877", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762877", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061IAC9", "url": "https://www.orthodb.org/?gene=A0A061IAC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31433", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31433", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31433:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31433:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027265066", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265066", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IAC9", "url": "https://www.uniprot.org/uniprotkb/A0A061IAC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IAC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IAC9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASAVFEGTSLVNMFVRGCWVNGIRRLIVSRRGDEEEFFEIRTEWSDRSVLYLHRSFADLGRLCKRLRDAFPEDRPELARAPLRQGLLAIKEAHDIETRLNEVEKLLETVISMPCKYSRSEVVLTFFERSPLDQVLKNDNVHKIQPSFQSPVKISEIMRSNGFCLANTETIVIDHSIPNGKDQLLDADSTEHLFENGGEFTPELEDGDDPTAYVTNLSYYHLVPFETDILD", "length": 231, "header": "tr|A0A061IAC9-1|A0A061IAC9_CRIGR Isoform 1 of PX domain-containing protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Pxdc1 PE=4 SV=1 CANONICAL=A0A061IAC9-1" }, "isoforms": [ { "isoform_ac": "A0A061IAC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IAC9/entry#A0A061IAC9-1", "sequence": { "sequence": "MASAVFEGTSLVNMFVRGCWVNGIRRLIVSRRGDEEEFFEIRTEWSDRSVLYLHRSFADLGRLCKRLRDAFPEDRPELARAPLRQGLLAIKEAHDIETRLNEVEKLLETVISMPCKYSRSEVVLTFFERSPLDQVLKNDNVHKIQPSFQSPVKISEIMRSNGFCLANTETIVIDHSIPNGKDQLLDADSTEHLFENGGEFTPELEDGDDPTAYVTNLSYYHLVPFETDILD", "length": 231, "header": "tr|A0A061IAC9-1|A0A061IAC9_CRIGR Isoform 1 of PX domain-containing protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Pxdc1 PE=4 SV=1 CANONICAL=A0A061IAC9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IAC9", "url": "https://www.uniprot.org/uniprotkb/A0A061IAC9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IAC9", "url": "https://www.uniprot.org/uniprotkb/A0A061IAC9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762877", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762877", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A061IAC9", "url": "https://www.uniprot.org/uniprotkb/A0A061IAC9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061IAC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAC9" }, { "id": "PS50195", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50195" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PX", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 134, "start_aa": "Met", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 216, "end_pos": 218 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061IAE6-1", "uniprot_ac": "A0A061IAE6", "uniprot_id": "A0A061IAE6_CRIGR", "mass": { "chemical_mass": 47448.0, "monoisotopic_mass": 47448.0 }, "refseq": { "ac": "XP_003508583", "name": "UPF0183 protein C16orf70 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508583" }, "gene_names": [ { "name": "C3H16orf70", "type": "recommended", "evidence": [ { "id": "A0A061IAE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAE6" } ] }, { "name": "C3H16orf70", "type": "synonym", "evidence": [ { "id": "XP_003508583", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508583" } ] } ], "protein_names": [ { "name": "UPF0183 protein C16orf70 homolog", "type": "synonym", "evidence": [ { "id": "XP_003508583", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508583" }, { "id": "A0A061IAE6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAE6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614552.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003508583", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508583" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IAE6", "url": "https://www.uniprot.org/uniprotkb/A0A061IAE6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "C3H16orf70", "url": "https://www.uniprot.org/uniprotkb/A0A061IAE6", "locus": {} } ], "crossref": [ { "id": "100758102", "url": "https://www.ncbi.nlm.nih.gov/gene/100758102", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758102", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758102", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YRKNDQK", "url": "https://omabrowser.org/oma/group/YRKNDQK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061IAE6", "url": "https://www.orthodb.org/?gene=A0A061IAE6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13465", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13465", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13465:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13465:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03676", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03676", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003508583", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508583", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IAE6", "url": "https://www.uniprot.org/uniprotkb/A0A061IAE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IAE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IAE6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLDLEVVPERSLGNEQWEFTLGMPLAQAVAILQKHCRIIKNVQVLYSEQSPLSHDLILNLTQDGIKLLFDAFNQRLKVIEVYDLTKVKLKYCGVHFNSQAIAPTIEQIDQSFGATHPGVYNSAEQLFHLNFRGLSFSFQLDSWTEAPKYEPNFAHGLASLQIPHGATVKRMYIYSGNSLQDTKAPVMPLSCFLGNVYAESVDVLRDGTGPSGLRLRLLAAGCGPGVLADAKMRVFERSVYFGDSCQDVLSMLGSPHKVFYKSEDKMKIHSPSPHKQVPSKCNDYFFNYFTLGVDILFDANTHKVKKFVLHTNYPGHYNFNIYHRCEFKIPLAVKKENAGGQTETCTTYSKWDNIQELLGHPVEKPVVLHRSSSPNNTNPFGSTFCFGLQRMIFEVMQNNHIASVTLYGPPRPGAHLRTAELP", "length": 422, "header": "tr|A0A061IAE6-1|A0A061IAE6_CRIGR Isoform 1 of UPF0183 protein C16orf70 homolog OS=Cricetulus griseus OX=10029 GN=C3H16orf70 PE=3 SV=1 CANONICAL=A0A061IAE6-1" }, "isoforms": [ { "isoform_ac": "A0A061IAE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IAE6/entry#A0A061IAE6-1", "sequence": { "sequence": "MLDLEVVPERSLGNEQWEFTLGMPLAQAVAILQKHCRIIKNVQVLYSEQSPLSHDLILNLTQDGIKLLFDAFNQRLKVIEVYDLTKVKLKYCGVHFNSQAIAPTIEQIDQSFGATHPGVYNSAEQLFHLNFRGLSFSFQLDSWTEAPKYEPNFAHGLASLQIPHGATVKRMYIYSGNSLQDTKAPVMPLSCFLGNVYAESVDVLRDGTGPSGLRLRLLAAGCGPGVLADAKMRVFERSVYFGDSCQDVLSMLGSPHKVFYKSEDKMKIHSPSPHKQVPSKCNDYFFNYFTLGVDILFDANTHKVKKFVLHTNYPGHYNFNIYHRCEFKIPLAVKKENAGGQTETCTTYSKWDNIQELLGHPVEKPVVLHRSSSPNNTNPFGSTFCFGLQRMIFEVMQNNHIASVTLYGPPRPGAHLRTAELP", "length": 422, "header": "tr|A0A061IAE6-1|A0A061IAE6_CRIGR Isoform 1 of UPF0183 protein C16orf70 homolog OS=Cricetulus griseus OX=10029 GN=C3H16orf70 PE=3 SV=1 CANONICAL=A0A061IAE6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IAE6", "url": "https://www.uniprot.org/uniprotkb/A0A061IAE6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IAE6", "url": "https://www.uniprot.org/uniprotkb/A0A061IAE6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758102", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758102", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A2V6-1", "protein_name": "Phagosome assembly factor 1", "gene_name": "PHAF1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLDLEVVPERSLGNEQWEFALGMPLAQAVAILQKHCRIIKNVQVLYSEQSPLSHDLILNLTQDGIKLLFDAFNQRLKVIEVYDLTKVKLKYCGVHFNSQAIAPTIEQIDQSFGATHPGVYNSAEQLFHLNFRGLSFSFQLDSWIEAPKYEPNFAHGLASLQIPHGATVKRMYIYSGNSLQDTKAPVMPLSCFLGNVYAESVDVLRDGTGPSGLRLRLLAAGCGPGLLADAKMRVFERSVYFGDSCQDVLSMLGSPHKVFYKSEDKMKIHSPSPHKQVPSKCNDYFFNYFTLGVDILFDANTHKVKKFVLHTNYPGHYNFNIYHRCEFKIPLTIKRENTDGQTETCTTYSKWDNIQELLGHPVEKPVVLHRSSSPNNTNPFGSTFCFGLQRMIFEVMQNNHIASVTLYGPPRPGAHLRTAELP", "length": 422 }, "evidence": [ { "id": "A0A061IAE6", "url": "https://omabrowser.org/oma/group/A0A061IAE6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A3Q1MQA6-1", "protein_name": "Phagosome assembly factor 1", "gene_name": "PHAF1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLDLEVVPERSLGNEQWEFALGMPLAQAVAILQKHCRIIKNVQVLYSEQSPLSHDLILNLTQDGIKLLFDAFNQRLKVIEVYDLTKVKLKYCGVHFNSQAIAPTIEQIDQSFGATHPGVYNSAEQLFHLNFRGLSFSFQLDSWTEAPKYEPNFAHGLASLQIPHGATVKRMYIYSGNSLQDTKAPVMPLSCFLGNVYAESVDVLRDGTGPSGLRLRLLAAGCGPGLLADAKMRVFERSVYFGDSCQDVLSMLGSPHKVFYKSEDKMKIHSPSPHKQVPSKCNDYFFNYFTLGVDILFDANTHKVKKFVLHTNYPGHYNFNIYHRCEFKIPLTVKRENTEGQTETCTTYSKWDNIQELLGHPVEKPVVLHRSSSPNNTNPFGSTFCFGLQRMIFEVMQNNHIASVTLYGPPRPGAHLRTAELP", "length": 422 }, "evidence": [ { "id": "A0A061IAE6", "url": "https://omabrowser.org/oma/group/A0A061IAE6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O08654-1", "protein_name": "Phagosome assembly factor 1", "gene_name": "Phaf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLDLEVVPERSLGNEQWEFTLGMPLAQAVAILQKHCRIIKNVQVLYSEQSPLSHDLILNLTQDGIKLLFDAFNQRLKVIEVYDLTKVKLKYCGVHFNSQAIAPTIEQIDQSFGATHPGVYNSAEQLFHLNFRGLSFSFQLDSWTEAPKYEPNFAHGLASLQIPHGATVKRMYIYSGNSLQDTKAPMMPLSCFLGNVYAESVDVIRDGTGPSGLRLRLLAAGCGPGVLADAKMRVFERAVYFGDSCQDVLSMLGSPHKVFYKSEDKMKIHSPSPHKQVPSKCNDYFFNYFTLGVDILFDANTHKVKKFVLHTNYPGHYNFNIYHRCEFKIPLAIKKENAGGQTEICTTYSKWDSIQELLGHPVEKPVVLHRSSSPNNTNPFGSTFCFGLQRMIFEVMQNNHIASVTLYGPPRPGAHLRTAELP", "length": 422 }, "evidence": [ { "id": "A0A061IAE6", "url": "https://omabrowser.org/oma/group/A0A061IAE6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q1LV04-1", "protein_name": "Phagosome assembly factor 1", "gene_name": "phaf1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLDLEVVPERSLGNEQWEFALGMPLAQAISILQKHCRIIKNVQVLYSEQMPLSHDLILNLTQDGIKLLFDACNQRLKVIEVYDLTKVKLKYCGVHFNSQAIAPTIEQIDQSFGATHPGVYNAAEQLFHLNFRGLSFSFQLDSWSEAPKYEPNFAHGLASLQIPHGATVKRMYIYSGNNLQETKAPAMPLACFLGNVYAECVEVLRDGAGPLGLKLRLLTAGCGPGVLADTKVRAVERSIYFGDSCQDVLSALGSPHKVFYKSEDKMKIHSPSPHKQVPSKCNDYFFNYYILGVDILFDSTTHLVKKFVLHTNFPGHYNFNIYHRCDFKIPLIIKKDGADAHSEDCILTTYSKWDQIQELLGHPMEKPVVLHRSSSANNTNPFGSTFCFGLQRMIFEVMQNNHIASVTLYGAPRPSSLARVEQSTH", "length": 425 }, "evidence": [ { "id": "A0A061IAE6", "url": "https://omabrowser.org/oma/group/A0A061IAE6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q922R1-1", "protein_name": "Phagosome assembly factor 1", "gene_name": "Phaf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLDLEVVPERSLGNEQWEFTLGMPLAQAVAILQKHCRIIRNVQVLYSEQSPLSHDLILNLTQDGITLLFDAFNQRLKVIEVCELTKVKLKYCGVHFNSQAIAPTIEQIDQSFGATHPGVYNSTEQLFHLNFRGLSFSFQLDSWTEAPKYEPNFAHGLASLQIPHGATVKRMYIYSGNSLQDTKAPVMPLSCFLGNVYAESVDVLRDGTGPSGLRLRLLAAGCGPGVLADAKMRVFERAVYFGDSCQDVLSMLGSPHKVFYKSEDKMKIHSPSPHKQVPSKCNDYFFNYFTLGVDILFDANTHKVKKFVLHTNYPGHYNFNIYHRCEFKIPLAIKKENAGGQTEICTTYSKWDSIQELLGHPVEKPVVLHRSSSPNNTNPFGSTFCFGLQRMIFEVMQNNHIASVTLYGPPRPGAHLRTAELP", "length": 422 }, "evidence": [ { "id": "A0A061IAE6", "url": "https://omabrowser.org/oma/group/A0A061IAE6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BSU1-1", "protein_name": "Phagosome assembly factor 1", "gene_name": "PHAF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLDLEVVPERSLGNEQWEFTLGMPLAQAVAILQKHCRIIKNVQVLYSEQSPLSHDLILNLTQDGIKLMFDAFNQRLKVIEVCDLTKVKLKYCGVHFNSQAIAPTIEQIDQSFGATHPGVYNSAEQLFHLNFRGLSFSFQLDSWTEAPKYEPNFAHGLASLQIPHGATVKRMYIYSGNSLQDTKAPMMPLSCFLGNVYAESVDVLRDGTGPAGLRLRLLAAGCGPGLLADAKMRVFERSVYFGDSCQDVLSMLGSPHKVFYKSEDKMKIHSPSPHKQVPSKCNDYFFNYFTLGVDILFDANTHKVKKFVLHTNYPGHYNFNIYHRCEFKIPLAIKKENADGQTETCTTYSKWDNIQELLGHPVEKPVVLHRSSSPNNTNPFGSTFCFGLQRMIFEVMQNNHIASVTLYGPPRPGSHLRTAELP", "length": 422 }, "evidence": [ { "id": "A0A061IAE6", "url": "https://omabrowser.org/oma/group/A0A061IAE6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9SD33-1", "protein_name": "PHAF1 protein At3g51130", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKDYSKIGDKLVMQRPRRRLEGTAMGATVFDLRPGVGIGPFSIGMPICEAFAQIEQQPNIYDVVHVKYYDEDPLKLDVVISFPDHGFHLRFDPWSQRLRLVEIFDVKRLQMRYATSMIGGPSTLATFVAVYALFGPTFPGIYDKERGIYSLFYPGLSFEFPIPNQYTDCCHDGEAALPLEFPDGTTPVTCRVSIYDNSSDKKVGVGKLMDRASVPPLPPGSLYMEEVHVKPGKELYFTVGGQHMPFGASPQDVWTELGRPCGIHPKQVDQMVIHSASDPRPKTTICGDYFYNYFTRGLDILFDGETHKVKKFVLHTNYPGHADFNSYIKCNFVISAGADAAEANRSGNKITPSTNWDQVKEILGECGPAAIQTQGSTSNPFGSTYVYGYQNVAFEVMKNGHIATITLFQS", "length": 410 }, "evidence": [ { "id": "A0A061IAE6", "url": "https://omabrowser.org/oma/group/A0A061IAE6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VSH9-1", "protein_name": "PHAF1 protein CG7083", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLDLEIVPEISLGCDAWEFVLGMHFSQAIAIIQSQVGIIKGVQVLYSDTTPLGVDIIINLPQDGVRLIFDPVSQRLKTIEVFNMKLVKLRYFGVYFNSPEVLPSIEQIEHSFGATHPGVYDAAKQLFALHFRGLSFYFPVDSKLHSGYAHGLSSLVFLNGASPVVSKMSLYAGSNVLENRVPSLPLSCYHRQMYLESATVLRTAFGHTKGLKLKLFTEGSGRALEPRRQCFTRELLFGDSCEDVATSLGAPNRIFFKSEDKMKIHSSSVNRQAQSKRSDIFFNYFTLGIDVLFDARTQTCKKFILHTNYPGHFNFNMYHRCEFQFLLQADHPSMSDSGHDLVTPTKQEHVNITAYTKWDAISSALATSERPVVLHRASSTNTANPFGSTFCYGYQDLIFEVMPNSHIASVTLYNTAPPRQPAHSWQQHKMQDIRLTVA", "length": 438 }, "evidence": [ { "id": "A0A061IAE6", "url": "https://omabrowser.org/oma/group/A0A061IAE6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A061IAE6", "url": "https://www.uniprot.org/uniprotkb/A0A061IAE6" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030672", "evidence": [ { "database": "UniProtKB", "id": "A0A061IAE6", "url": "https://www.uniprot.org/uniprotkb/A0A061IAE6" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A061IAE6", "url": "https://www.uniprot.org/uniprotkb/A0A061IAE6" } ], "pmid": "" }, { "name": "phagophore assembly site", "id": "GO:0000407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000407", "evidence": [ { "database": "UniProtKB", "id": "A0A061IAE6", "url": "https://www.uniprot.org/uniprotkb/A0A061IAE6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "Golgi to plasma membrane protein transport", "id": "GO:0043001", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043001", "evidence": [ { "database": "UniProtKB", "id": "A0A061IAE6", "url": "https://www.uniprot.org/uniprotkb/A0A061IAE6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" }, { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 375, "end_pos": 377 }, { "start_pos": 59, "end_pos": 61 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061IAE7-1", "uniprot_ac": "A0A061IAE7", "uniprot_id": "A0A061IAE7_CRIGR", "mass": { "chemical_mass": 122487.0, "monoisotopic_mass": 122487.0 }, "refseq": { "ac": "XP_027262012", "name": "zinc finger SWIM domain-containing protein 4 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262012" }, "gene_names": [ { "name": "Zswim4", "type": "recommended", "evidence": [ { "id": "A0A061IAE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAE7" } ] }, { "name": "Zswim4", "type": "synonym", "evidence": [ { "id": "XP_027262012", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262012" } ] } ], "protein_names": [ { "name": "Zinc finger SWIM domain-containing protein 4 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A061IAE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IAE7/entry#names_and_taxonomy" } ] }, { "name": "zinc finger SWIM domain-containing protein 4 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027262012", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262012" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027262012", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262012" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IAE7", "url": "https://www.uniprot.org/uniprotkb/A0A061IAE7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Zswim4", "url": "https://www.uniprot.org/uniprotkb/A0A061IAE7", "locus": {} } ], "crossref": [ { "id": "100758751", "url": "https://www.ncbi.nlm.nih.gov/gene/100758751", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007527", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007527", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758751", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758751", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061IAE7", "url": "https://www.orthodb.org/?gene=A0A061IAE7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22619", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22619", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22619:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22619:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21055", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21055", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027262012", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027262012", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IAE7", "url": "https://www.uniprot.org/uniprotkb/A0A061IAE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IAE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IAE7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPPAAKRSRGCPAGDEPGTGARRGRPEPLLDLSAKRVAESWAFEQVEERFSRVPEPVQKRIVFWSFPRSEREICMYSSLGYQPPEGEQDTRVPFTRGLHLLQSGAVDRVLQVGFHLSGNIRELGAPGEPEHLYHVSISFDRCKITSVSCGCDNRDLFYCAHVVALSLYRIRHAHQVELRLPISETLSQMNRDQLQKFVQYLISAHHTEVLPTAQRLADEILLLGSEINLVHGAPDPTAGAGTEDANCWHLDEEQIQEQVKQLLSNGGHYGASQQLRSMFSKVREMLRARDSNGARMLILMTEQFLQDPRLALWRQQGAGMTDKCRQLWDELGALWVCVILSPHCKPDERSGWLQLLGTWDKLDVCPLEEGNYSLDTPGLQPALTSRAGSENEEEALTAASPRRTVFSRALQAGDLHWNDSHLQRILASDSCGPSLTGNMGGDKPTFDPQGHPIWLGEPFPTACARVDTLRAHGYPHKALRLACAIVNALRLQRRHQLENYKQQKKELLQKGATCLTSTEGWVGHPLDPIGCLCRALLEACRLEEEPHSLYPDLTTEKRKVPYQHVPVPGSPGESYLALALEVALLGLGQQRALPEGLYAQDKVVRNEEQLLALLEEVELDERLVQVLRKQAGLLLEGGPFSGFGEVIFRESVPMHTCARYLFAALLPHDPDLAFRLALRAMRLPVLETTFPAGEAHPNPLDSIMSNRFPRWFILGHLETRQCELASTMLTAAKGDTKWLHAVLGSVQQNIHSPALLFKLAQDACKTATPANAPPDTMLLGIALELGLQVMRMTLNTMTWRRREMVRWLVSCATEIGPPALMSIMKNWYSLFTPVEAVTIVAVTGTTHATLLRLQLDTAGREELWAGARTLALQCAMKDPQNCALPALTLCEKNHAAFEAAYQIVLDAAAGGLGHAHLFTVARYMEHRGLPLRAYKLATLALAQLSIAFNQDSHPAVNDVLWACSLSHSLGRHELSAIVPLIIRSIHCAPMLSDILRRWTLSAPGLGPLGARRATKPLGTDRAPLCQLLDAAVAAYITTSHSRLTHISPRHYGDFIEFLGKARETFLLAPDGHLQFAQFLENLKQTYKGKKKLMLLVRERFG", "length": 1102, "header": "tr|A0A061IAE7-1|A0A061IAE7_CRIGR Isoform 1 of Zinc finger SWIM domain-containing protein 4 isoform X2 OS=Cricetulus griseus OX=10029 GN=Zswim4 PE=4 SV=1 CANONICAL=A0A061IAE7-1" }, "isoforms": [ { "isoform_ac": "A0A061IAE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IAE7/entry#A0A061IAE7-1", "sequence": { "sequence": "MEPPAAKRSRGCPAGDEPGTGARRGRPEPLLDLSAKRVAESWAFEQVEERFSRVPEPVQKRIVFWSFPRSEREICMYSSLGYQPPEGEQDTRVPFTRGLHLLQSGAVDRVLQVGFHLSGNIRELGAPGEPEHLYHVSISFDRCKITSVSCGCDNRDLFYCAHVVALSLYRIRHAHQVELRLPISETLSQMNRDQLQKFVQYLISAHHTEVLPTAQRLADEILLLGSEINLVHGAPDPTAGAGTEDANCWHLDEEQIQEQVKQLLSNGGHYGASQQLRSMFSKVREMLRARDSNGARMLILMTEQFLQDPRLALWRQQGAGMTDKCRQLWDELGALWVCVILSPHCKPDERSGWLQLLGTWDKLDVCPLEEGNYSLDTPGLQPALTSRAGSENEEEALTAASPRRTVFSRALQAGDLHWNDSHLQRILASDSCGPSLTGNMGGDKPTFDPQGHPIWLGEPFPTACARVDTLRAHGYPHKALRLACAIVNALRLQRRHQLENYKQQKKELLQKGATCLTSTEGWVGHPLDPIGCLCRALLEACRLEEEPHSLYPDLTTEKRKVPYQHVPVPGSPGESYLALALEVALLGLGQQRALPEGLYAQDKVVRNEEQLLALLEEVELDERLVQVLRKQAGLLLEGGPFSGFGEVIFRESVPMHTCARYLFAALLPHDPDLAFRLALRAMRLPVLETTFPAGEAHPNPLDSIMSNRFPRWFILGHLETRQCELASTMLTAAKGDTKWLHAVLGSVQQNIHSPALLFKLAQDACKTATPANAPPDTMLLGIALELGLQVMRMTLNTMTWRRREMVRWLVSCATEIGPPALMSIMKNWYSLFTPVEAVTIVAVTGTTHATLLRLQLDTAGREELWAGARTLALQCAMKDPQNCALPALTLCEKNHAAFEAAYQIVLDAAAGGLGHAHLFTVARYMEHRGLPLRAYKLATLALAQLSIAFNQDSHPAVNDVLWACSLSHSLGRHELSAIVPLIIRSIHCAPMLSDILRRWTLSAPGLGPLGARRATKPLGTDRAPLCQLLDAAVAAYITTSHSRLTHISPRHYGDFIEFLGKARETFLLAPDGHLQFAQFLENLKQTYKGKKKLMLLVRERFG", "length": 1102, "header": "tr|A0A061IAE7-1|A0A061IAE7_CRIGR Isoform 1 of Zinc finger SWIM domain-containing protein 4 isoform X2 OS=Cricetulus griseus OX=10029 GN=Zswim4 PE=4 SV=1 CANONICAL=A0A061IAE7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 238, "start_aa": "Thr", "end_pos": 238, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr238", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IAE7", "url": "https://www.uniprot.org/uniprotkb/A0A061IAE7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035297541", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297541" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061ICC1", "url": "https://www.uniprot.org/uniprotkb/A0A061ICC1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100761955", "url": "https://www.uniprot.org/uniprotkb/A0A061ICC1", "locus": {} } ], "crossref": [ { "id": "100761955", "url": "https://www.ncbi.nlm.nih.gov/gene/100761955", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051036", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051036", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761955", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761955", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CELEVII", "url": "https://omabrowser.org/oma/group/CELEVII/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061ICC1", "url": "https://www.orthodb.org/?gene=A0A061ICC1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12035", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12035", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12035:SF137", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12035:SF137", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035297541", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297541", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061ICC1", "url": "https://www.uniprot.org/uniprotkb/A0A061ICC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061ICC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A061ICC1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLLLLWVCGWASENYFLLHAESMFMYETFKVELQSTLVTVQEGLCVFVPCTFFSLFKNPSFNTTVFGYWFRAGSNTDLDFPVATNNPDKTMQETHSQFHLFGDPRINDCSLDIRDAQRSDSGYYFFRTESDTFKWNYYKDQLFLNVTALNHTPNIDIPQTLELGHPSNVTCSVPWACEKGTPPIFSWMSAALTSLGPRTTLSSVLTLTPRLQDHGTNLVCQVTFPGAGVTVQKAVQINVTWKSGTLAEVVLVAMGEAAIKFLLLGICFIFLSMESQRRRVERPATQVDYAETVMD", "length": 296, "header": "tr|A0A061ICC1-1|A0A061ICC1_CRIGR Isoform 1 of Myeloid cell surface antigen CD33 OS=Cricetulus griseus OX=10029 GN=LOC100761955 PE=3 SV=1 CANONICAL=A0A061ICC1-1" }, "isoforms": [ { "isoform_ac": "A0A061ICC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A061ICC1/entry#A0A061ICC1-1", "sequence": { "sequence": "MLLLLLWVCGWASENYFLLHAESMFMYETFKVELQSTLVTVQEGLCVFVPCTFFSLFKNPSFNTTVFGYWFRAGSNTDLDFPVATNNPDKTMQETHSQFHLFGDPRINDCSLDIRDAQRSDSGYYFFRTESDTFKWNYYKDQLFLNVTALNHTPNIDIPQTLELGHPSNVTCSVPWACEKGTPPIFSWMSAALTSLGPRTTLSSVLTLTPRLQDHGTNLVCQVTFPGAGVTVQKAVQINVTWKSGTLAEVVLVAMGEAAIKFLLLGICFIFLSMESQRRRVERPATQVDYAETVMD", "length": 296, "header": "tr|A0A061ICC1-1|A0A061ICC1_CRIGR Isoform 1 of Myeloid cell surface antigen CD33 OS=Cricetulus griseus OX=10029 GN=LOC100761955 PE=3 SV=1 CANONICAL=A0A061ICC1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061ICC1", "url": "https://www.uniprot.org/uniprotkb/A0A061ICC1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761955", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761955", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZAH6-1", "protein_name": "Sialic acid binding Ig-like lectin H", "gene_name": "Siglech", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"evidence": [ { "database": "UniProtKB", "id": "A0A061ICC1", "url": "https://www.uniprot.org/uniprotkb/A0A061ICC1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "sialic acid binding", "id": "GO:0033691", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033691", "evidence": [ { "database": "UniProtKB", "id": "A0A061ICC1", "url": "https://www.uniprot.org/uniprotkb/A0A061ICC1" } ], "pmid": "" }, { "name": "monosaccharide binding", "id": "GO:0048029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048029", "evidence": [ { "database": "UniProtKB", "id": "A0A061ICC1", "url": "https://www.uniprot.org/uniprotkb/A0A061ICC1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 239, "end_pos": 241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061ICC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ICC1" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 154, "end_pos": 237, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 146, "end_pos": 148 }, { "start_pos": 151, "end_pos": 153 }, { "start_pos": 169, "end_pos": 171 }, { "start_pos": 239, "end_pos": 241 }, { "start_pos": 63, "end_pos": 65 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061ICF2-1", "uniprot_ac": "A0A061ICF2", "uniprot_id": "A0A061ICF2_CRIGR", "mass": { "chemical_mass": 13496.0, "monoisotopic_mass": 13496.0 }, "refseq": { "ac": "XP_003510271", "name": "melanoma antigen recognized by T-cells 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510271" }, "gene_names": [ { "name": "Mlana", "type": "recommended", "evidence": [ { "id": "A0A061ICF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ICF2" } ] }, { "name": "Mlana", "type": "synonym", "evidence": [ { "id": "XP_003510271", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510271" } ] } ], "protein_names": [ { "name": "Melanoma antigen recognized by T-cells 1", "type": "synonym", "evidence": [ { "id": "A0A061ICF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ICF2/entry#names_and_taxonomy" } ] }, { "name": "melanoma antigen recognized by T-cells 1", "type": "synonym", "evidence": [ { "id": "XP_003510271", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510271" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614848.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003510271", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510271" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061ICF2", "url": "https://www.uniprot.org/uniprotkb/A0A061ICF2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mlana", "url": "https://www.uniprot.org/uniprotkb/A0A061ICF2", "locus": {} } ], "crossref": [ { "id": "100762259", "url": "https://www.ncbi.nlm.nih.gov/gene/100762259", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029242", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029242", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762259", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762259", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061ICF2", "url": "https://www.orthodb.org/?gene=A0A061ICF2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15305", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15305", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15305:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15305:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14991", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14991", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003510271", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510271", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061ICF2", "url": "https://www.uniprot.org/uniprotkb/A0A061ICF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061ICF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061ICF2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPREDAHFGYPRKEHSHSYITTEEAAGIGILIVVLGIALLIGCWYCRRRSGYRTLRDKRLHAGPRSPRKESCPGEQCSCDGLGLQDSPLPFQEKTHQPVVPNAPPAYEKLSSDQLPPPYSP", "length": 121, "header": "tr|A0A061ICF2-1|A0A061ICF2_CRIGR Isoform 1 of Melanoma antigen recognized by T-cells 1 OS=Cricetulus griseus OX=10029 GN=Mlana PE=4 SV=1 CANONICAL=A0A061ICF2-1" }, "isoforms": [ { "isoform_ac": "A0A061ICF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061ICF2/entry#A0A061ICF2-1", "sequence": { "sequence": "MPREDAHFGYPRKEHSHSYITTEEAAGIGILIVVLGIALLIGCWYCRRRSGYRTLRDKRLHAGPRSPRKESCPGEQCSCDGLGLQDSPLPFQEKTHQPVVPNAPPAYEKLSSDQLPPPYSP", "length": 121, "header": "tr|A0A061ICF2-1|A0A061ICF2_CRIGR Isoform 1 of Melanoma antigen recognized by T-cells 1 OS=Cricetulus griseus OX=10029 GN=Mlana PE=4 SV=1 CANONICAL=A0A061ICF2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061ICF2", "url": "https://www.uniprot.org/uniprotkb/A0A061ICF2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061ICF2", "url": "https://www.uniprot.org/uniprotkb/A0A061ICF2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762259", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762259", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A061ICF2", "url": "https://www.uniprot.org/uniprotkb/A0A061ICF2" } ], "pmid": "" }, { "name": "melanosome", "id": "GO:0042470", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042470", "evidence": [ { "database": "UniProtKB", "id": 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This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027264724", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264724" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061ICI5", "url": "https://www.uniprot.org/uniprotkb/A0A061ICI5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cracr2b", "url": "https://www.uniprot.org/uniprotkb/A0A061ICI5", "locus": {} } ], "crossref": [ { "id": "cd00051", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00051", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100754254", "url": "https://www.ncbi.nlm.nih.gov/gene/100754254", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754254", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754254", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CCHHLGT", "url": "https://omabrowser.org/oma/group/CCHHLGT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061ICI5", "url": "https://www.orthodb.org/?gene=A0A061ICI5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46311", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46311", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46311:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46311:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27574", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27574", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027264724", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264724", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061ICI5", "url": "https://www.uniprot.org/uniprotkb/A0A061ICI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061ICI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A061ICI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K552", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K552", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K552-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K552-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASPGQPGPGEGQEEEETKGISAGHRPEVLQQAQELFLLCDKDAKGFITRQDLQGLQSDLPLTPEQLEAVFESLDQAHTGFLTAREFCLGLGKFVGVESAQGGSSLRTPEETFESSTGGSLEEDDDVETFCTSLEKLGVARVLGEQWAVRTLWVRLQRERPELLGALEEVLMRASACLEAAARERDGLEQALRRRESEHEREVRGLYEELEQQLGEQRHRCQSQKLLPREEQRGHLELELQTREQELERAGLRQRELEQQLQARTAEQLEAQAQHTQLRRAYEVIRAQLDQAQEQLSRLEGEAQGRQEQTQRDVVAVSRNMQKEKLSLLRQLELLRELNLRLRDERDACETKLLGSSHRKALAIAHKPGPTYCCCCCGWARPPRRGSGHLPSAR", "length": 394, "header": "tr|A0A061ICI5-1|A0A061ICI5_CRIGR Isoform 1 of EF-hand calcium-binding domain-containing protein 4A isoform X1 OS=Cricetulus griseus OX=10029 GN=Cracr2b PE=4 SV=1 CANONICAL=A0A061ICI5-1" }, "isoforms": [ { "isoform_ac": "A0A061ICI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A061ICI5/entry#A0A061ICI5-1", "sequence": { "sequence": "MASPGQPGPGEGQEEEETKGISAGHRPEVLQQAQELFLLCDKDAKGFITRQDLQGLQSDLPLTPEQLEAVFESLDQAHTGFLTAREFCLGLGKFVGVESAQGGSSLRTPEETFESSTGGSLEEDDDVETFCTSLEKLGVARVLGEQWAVRTLWVRLQRERPELLGALEEVLMRASACLEAAARERDGLEQALRRRESEHEREVRGLYEELEQQLGEQRHRCQSQKLLPREEQRGHLELELQTREQELERAGLRQRELEQQLQARTAEQLEAQAQHTQLRRAYEVIRAQLDQAQEQLSRLEGEAQGRQEQTQRDVVAVSRNMQKEKLSLLRQLELLRELNLRLRDERDACETKLLGSSHRKALAIAHKPGPTYCCCCCGWARPPRRGSGHLPSAR", "length": 394, "header": "tr|A0A061ICI5-1|A0A061ICI5_CRIGR Isoform 1 of EF-hand calcium-binding domain-containing protein 4A isoform X1 OS=Cricetulus griseus OX=10029 GN=Cracr2b PE=4 SV=1 CANONICAL=A0A061ICI5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K552-1", "url": "https://www.uniprot.org/uniprotkb/A0A061ICI5/entry#A0A9J7K552-1", "sequence": { "sequence": "MASPGQPGPGEGQEEEETKGISAGHRPEVLQQAQELFLLCDKDAKGFITRQDLQGLQSDLPLTPEQLEAVFESLDQAHTGFLTAREFCLGLGKFVGVESAQGGSSLRTPEETFESSTGGSLEEDDDVETFCTSLEKLGVARVLGEQWAVRTLWVRLQRERPELLGALEEVLMRASACLEAAARERDGLEQALRRRESEHEREVRGLYEELEQQLGEQRHRCQSQKLLPREEQRGHLELELQTREQELERAGLRQRERCGCCLQEHAEGETQSPKAAGAAEVGQAYLGCVEKWFQVPE", "length": 297, "header": "tr|A0A9J7K552-1|A0A9J7K552_CRIGR Computationally mapped isoform of EF-hand calcium-binding domain-containing protein 4A isoform X2 OS=Cricetulus griseus OX=10029 GN=Cracr2b PE=4 SV=1 CANONICAL=A0A061ICI5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061ICI5", "url": "https://www.uniprot.org/uniprotkb/A0A061ICI5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061ICI5", "url": "https://www.uniprot.org/uniprotkb/A0A061ICI5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754254", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754254", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B0BNK9-1", "protein_name": "EF-hand calcium-binding domain-containing protein 4A", "gene_name": "Cracr2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASPGPPGAGQGQEEEERAGVSAGHQAEVLQQAQELFVLCDKDAKGFITRQDLQGLQSDLPLTPEQLEAVFESLDQAHTGFLTAREFCLGLGKFVGVESVPGRAPLRTPEETFESGTGGSLEEEDDVETFYTSLEKLGVARVLGEQWAVRTLWVGLQRERPELLGSLEEILMRASACLEAAARERDGLEQALRRRESEHEREVRGLYEELEQQLREQRQRRQSQNPPREEERGHLELELQTREQELERAALRQRELEQQLQARAAEQLEVQAQHIQLQRAYEALRAQLDQAQEQLIRLEGEAQGRQEQTQRDVVAVSRNMQKEKLSLLRQLELLRELNLRLRDERDACETKLLGSSHRKALAIAHKPGPIYCCCCCGWARPPRRGSGHLPSAR", "length": 393 }, "evidence": [ { "id": "A0A061ICI5", "url": "https://omabrowser.org/oma/group/A0A061ICI5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3L6X5-1", "protein_name": "Calcium release activated channel regulator 2B", "gene_name": "CRACR2B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": 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"MASPGLPGSGEGQEGEETTGVSARHGVEVLQQAQELFLLCDKDAKGFITRQDLQGLQSDLPLTPEQLEAVFESLDQAHTGFLTAREFCLGLGKFVGVESAPGGSPLRTSEETFESGTGGSLEEEEEDVETFYTSLEKLGVARVLGEQWAVRTLWVGLQRERPELLGSLEEVLMRASACLEAAAREREGLEQALRRRESEHEREVRGLYEELEQQLGEQRHRRQSQNLPREEQRGHLELELQTREQELERAGLRQRELEQQLQARAAEQLEAQAQHIQLQRAYEAIRAQLDQAQEQLSRLEGEAQGRQEQTQRDVVAVSRNMQKEKLSLLRQLELLRELNLRLRDERDACETKLLGSSHRKALAIAHKPGPIYCCCCCGWARPPRRGSGHLPSAR", "length": 394 }, "evidence": [ { "id": "A0A061ICI5", "url": "https://omabrowser.org/oma/group/A0A061ICI5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N4Y2-1", "protein_name": "EF-hand calcium-binding domain-containing protein 4A", "gene_name": "CRACR2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027265960", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265960" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061ID74", "url": "https://www.uniprot.org/uniprotkb/A0A061ID74" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Itpripl2", "url": "https://www.uniprot.org/uniprotkb/A0A061ID74", "locus": {} } ], "crossref": [ { "id": "100756036", "url": "https://www.ncbi.nlm.nih.gov/gene/100756036", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026250", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026250", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756036", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756036", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061ID74", "url": "https://www.orthodb.org/?gene=A0A061ID74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10656", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10656", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10656:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10656:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF20266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027265960", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265960", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061ID74", "url": "https://www.uniprot.org/uniprotkb/A0A061ID74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061ID74-1", "url": "https://www.uniprot.org/uniprotkb/A0A061ID74-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVRYTLNLKVFWPVVTGLCTALVCLYHALRSSEGARAESPDGADSGFPLLKVAILLLLGYILLRCRHTIRQRLLPGSSRPCGHANFSARPLQEPGLSILLESYYEHEVRLSPHVLGHSKAHVSRIVGELVQAGRARGSPGPITGGALALAFRGDFIQVGSAYEQHKIRRPDSFDVLVPLRLPPQVALEPRSLGTEPTLAPAFRSCFVCALKAPPSPSGTTTGQWHRDCKPFAEGFCVDVQGRRHLSATLVLRWFQAHLQRSLATVRYSLEGRCRVSLTPGGLEQPPTLHILPCRTDYGCCRLSMAVRLIPAVHLGDGVFLVAPPPPPSPSGALSELPGGLRAEALWGVNTARQEQKLLGWLQERAPPGACYLKCLQLLKALRDLGARGLDPTAATQWGRILSSYVLKTVLLTVFLNEGGPTHSWDEAHLSECLEKLVKFLRDCLLRRRDLFHCVLGPGGAAAEVGPLPKALREAAPVDLLAPFDLHARELAAARLLSIWRRLPQLLRAYGGPRYLARCPTPRSQRIQGFPEDEP", "length": 535, "header": "tr|A0A061ID74-1|A0A061ID74_CRIGR Isoform 1 of Inositol 1,4,5-trisphosphate receptor-interacting protein-like 2 OS=Cricetulus griseus OX=10029 GN=Itpripl2 PE=3 SV=1 CANONICAL=A0A061ID74-1" }, "isoforms": [ { "isoform_ac": "A0A061ID74-1", "url": "https://www.uniprot.org/uniprotkb/A0A061ID74/entry#A0A061ID74-1", "sequence": { "sequence": "MSVRYTLNLKVFWPVVTGLCTALVCLYHALRSSEGARAESPDGADSGFPLLKVAILLLLGYILLRCRHTIRQRLLPGSSRPCGHANFSARPLQEPGLSILLESYYEHEVRLSPHVLGHSKAHVSRIVGELVQAGRARGSPGPITGGALALAFRGDFIQVGSAYEQHKIRRPDSFDVLVPLRLPPQVALEPRSLGTEPTLAPAFRSCFVCALKAPPSPSGTTTGQWHRDCKPFAEGFCVDVQGRRHLSATLVLRWFQAHLQRSLATVRYSLEGRCRVSLTPGGLEQPPTLHILPCRTDYGCCRLSMAVRLIPAVHLGDGVFLVAPPPPPSPSGALSELPGGLRAEALWGVNTARQEQKLLGWLQERAPPGACYLKCLQLLKALRDLGARGLDPTAATQWGRILSSYVLKTVLLTVFLNEGGPTHSWDEAHLSECLEKLVKFLRDCLLRRRDLFHCVLGPGGAAAEVGPLPKALREAAPVDLLAPFDLHARELAAARLLSIWRRLPQLLRAYGGPRYLARCPTPRSQRIQGFPEDEP", "length": 535, "header": "tr|A0A061ID74-1|A0A061ID74_CRIGR Isoform 1 of Inositol 1,4,5-trisphosphate receptor-interacting protein-like 2 OS=Cricetulus griseus OX=10029 GN=Itpripl2 PE=3 SV=1 CANONICAL=A0A061ID74-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"MRPHLAAAAPREARRERCFRRGSAPPGRAHREAPPQAVLEPSVCQVPVTFRDVAMYFCREEWECLSPSQRTLYREVMLENFRNFIELGYCGPRPDLISHLEQWDEPWVEDQDIPKFLEARKGVCSGGRKSVDQKRPCDLASAHERAHPRMGAKRGATMRKSVLTAGKVHLPRDTSGKKVDKQKAFQDQLCGKSYRKQLGLKEQCKSGAEGHPFICGTCGKALSCHSRLAAHQTVHTGTRSFECFECGQTFRWVSNLLRHQRNHTSEKPFCCEVCGQAFSLKDRLAQHRKIHTEHRPYVCSDCGKAFKQKSNLLRHKLVHTGERPFYCDNCGKAFRTKENLSHHQRIHSGEKPYTCGQCGKAFRWPKGFSIHQRLHLTKRFYECEHCGKGFRHLGFFTRHQRTHGRGEV", "length": 408, "header": "tr|A0A061ID85-1|A0A061ID85_CRIGR Isoform 1 of Zinc finger protein 707 isoform X1 OS=Cricetulus griseus OX=10029 GN=Znf707 PE=3 SV=1 CANONICAL=A0A061ID85-1" }, "isoforms": [ { "isoform_ac": "A0A061ID85-1", "url": "https://www.uniprot.org/uniprotkb/A0A061ID85/entry#A0A061ID85-1", "sequence": { "sequence": "MRPHLAAAAPREARRERCFRRGSAPPGRAHREAPPQAVLEPSVCQVPVTFRDVAMYFCREEWECLSPSQRTLYREVMLENFRNFIELGYCGPRPDLISHLEQWDEPWVEDQDIPKFLEARKGVCSGGRKSVDQKRPCDLASAHERAHPRMGAKRGATMRKSVLTAGKVHLPRDTSGKKVDKQKAFQDQLCGKSYRKQLGLKEQCKSGAEGHPFICGTCGKALSCHSRLAAHQTVHTGTRSFECFECGQTFRWVSNLLRHQRNHTSEKPFCCEVCGQAFSLKDRLAQHRKIHTEHRPYVCSDCGKAFKQKSNLLRHKLVHTGERPFYCDNCGKAFRTKENLSHHQRIHSGEKPYTCGQCGKAFRWPKGFSIHQRLHLTKRFYECEHCGKGFRHLGFFTRHQRTHGRGEV", "length": 408, "header": "tr|A0A061ID85-1|A0A061ID85_CRIGR Isoform 1 of Zinc finger protein 707 isoform X1 OS=Cricetulus griseus OX=10029 GN=Znf707 PE=3 SV=1 CANONICAL=A0A061ID85-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FLL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A061ID85/entry#A0A9J7FLL3-1", "sequence": { "sequence": "MYFCREEWECLSPSQRTLYREVMLENFRNFIELGYCGPRPDLISHLEQWDEPWVEDQDIPKFLEARKGVCSGGRKSVDQKRPCDLASAHERAHPRMGAKRGATMRKSVLTAGKVHLPRDTSGKKVDKQKAFQDQLCGKSYRKQLGLKEQCKSGAEGHPFICGTCGKALSCHSRLAAHQTVHTGTRSFECFECGQTFRWVSNLLRHQRNHTSEKPFCCEVCGQAFSLKDRLAQHRKIHTEHRPYVCSDCGKAFKQKSNLLRHKLVHTGERPFYCDNCGKAFRTKENLSHHQRIHSGEKPYTCGQCGKAFRWPKGFSIHQRLHLTKRFYECEHCGKGFRHLGFFTRHQRTHGRGEV", "length": 354, "header": "tr|A0A9J7FLL3-1|A0A9J7FLL3_CRIGR Computationally mapped isoform of Zinc finger protein 707 isoform X2 OS=Cricetulus griseus OX=10029 GN=Znf707 PE=3 SV=1 CANONICAL=A0A061ID85-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061ID85", "url": "https://www.uniprot.org/uniprotkb/A0A061ID85" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763645", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763645", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A061ID85", "url": "https://www.uniprot.org/uniprotkb/A0A061ID85" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A061ID85", "url": "https://www.uniprot.org/uniprotkb/A0A061ID85" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A061ID85", "url": "https://www.uniprot.org/uniprotkb/A0A061ID85" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A061ID85", "url": "https://www.uniprot.org/uniprotkb/A0A061ID85" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A061ID85", "url": "https://www.uniprot.org/uniprotkb/A0A061ID85" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated 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"interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061ID85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ID85" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 213, "end_pos": 240, "start_aa": "Phe", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A061ID85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ID85" }, { "id": "PS50805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KRAB", "eco_id": "ECO_0000259", "start_pos": 48, "end_pos": 119, "start_aa": "Val", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061IDJ3-1", "uniprot_ac": "A0A061IDJ3", "uniprot_id": "A0A061IDJ3_CRIGR", "mass": { "chemical_mass": 49600.0, "monoisotopic_mass": 49600.0 }, "refseq": { "ac": "XP_027257218", "name": "39S ribosomal protein S30, mitochondrial isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257218" }, "gene_names": [ { "name": "Mrps30", "type": "recommended", "evidence": [ { "id": "A0A061IDJ3", "database": "UniProtKB", 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027257218", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257218" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IDJ3", "url": "https://www.uniprot.org/uniprotkb/A0A061IDJ3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mrps30", "url": "https://www.uniprot.org/uniprotkb/A0A061IDJ3", "locus": {} } ], "crossref": [ { "id": "100753404", "url": "https://www.ncbi.nlm.nih.gov/gene/100753404", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010793", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010793", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039982", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039982", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753404", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753404", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061IDJ3", "url": "https://www.orthodb.org/?gene=A0A061IDJ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13014", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13014", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13014:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13014:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07147", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07147", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027257218", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257218", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IDJ3", "url": "https://www.uniprot.org/uniprotkb/A0A061IDJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IDJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IDJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAARCWQLVPRRGLSLHAAAEASASASKVSDPEVVATPVARYPPIVASMTADSKAARLRRVQRWQAAVHAAPSVDEKVRILTKMQFKKYMVYPQTFALNADRWYQGFTKTVFISGLPPAPAQSRPSLDLAGLRAAVCDCILQEHVYLRRRLRPHLFDRRQALVSPLLDRLVETLVSLLVPLNPALATAALDCKRPVDFYWLRGEECIPAGHRKGRIDALRYQINDKPHNQIRISQQLPEFVPLDYSIPVEIPVMKCKPDKLPLFKRQYENTIFTGSKTADPCCYGHTQFHLLPDRLNRDKLIKQNQTEQVEVVCRANALASLFAWTGAQAMYQGFWSEADVTRPFVSQGVITDGKYFSFFCYQLNTLALTVQADQNNSRKNICWGTQSKPLYETVEDNDVKGFDDNVLLQIVDFLLNKPKEDRTQLLGSQEKALDLGP", "length": 439, "header": "tr|A0A061IDJ3-1|A0A061IDJ3_CRIGR Isoform 1 of 39S ribosomal protein S30, mitochondrial isoform X2 OS=Cricetulus griseus OX=10029 GN=Mrps30 PE=4 SV=1 CANONICAL=A0A061IDJ3-1" }, "isoforms": [ { "isoform_ac": "A0A061IDJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IDJ3/entry#A0A061IDJ3-1", "sequence": { "sequence": "MAAARCWQLVPRRGLSLHAAAEASASASKVSDPEVVATPVARYPPIVASMTADSKAARLRRVQRWQAAVHAAPSVDEKVRILTKMQFKKYMVYPQTFALNADRWYQGFTKTVFISGLPPAPAQSRPSLDLAGLRAAVCDCILQEHVYLRRRLRPHLFDRRQALVSPLLDRLVETLVSLLVPLNPALATAALDCKRPVDFYWLRGEECIPAGHRKGRIDALRYQINDKPHNQIRISQQLPEFVPLDYSIPVEIPVMKCKPDKLPLFKRQYENTIFTGSKTADPCCYGHTQFHLLPDRLNRDKLIKQNQTEQVEVVCRANALASLFAWTGAQAMYQGFWSEADVTRPFVSQGVITDGKYFSFFCYQLNTLALTVQADQNNSRKNICWGTQSKPLYETVEDNDVKGFDDNVLLQIVDFLLNKPKEDRTQLLGSQEKALDLGP", "length": 439, "header": "tr|A0A061IDJ3-1|A0A061IDJ3_CRIGR Isoform 1 of 39S ribosomal protein S30, mitochondrial isoform X2 OS=Cricetulus griseus OX=10029 GN=Mrps30 PE=4 SV=1 CANONICAL=A0A061IDJ3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IDJ3", "url": "https://www.uniprot.org/uniprotkb/A0A061IDJ3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IDJ3", "url": "https://www.uniprot.org/uniprotkb/A0A061IDJ3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753404", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753404", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial large ribosomal subunit", "id": "GO:0005762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005762", "evidence": [ { "database": "UniProtKB", "id": "A0A061IDJ3", "url": "https://www.uniprot.org/uniprotkb/A0A061IDJ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A061IDJ3", "url": "https://www.uniprot.org/uniprotkb/A0A061IDJ3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A061IDJ3", "url": "https://www.uniprot.org/uniprotkb/A0A061IDJ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 377, "end_pos": 379, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 306, "end_pos": 308 }, { "start_pos": 377, "end_pos": 379 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061IDR1-1", "uniprot_ac": "A0A061IDR1", "uniprot_id": "A0A061IDR1_CRIGR", "mass": { "chemical_mass": 73463.0, "monoisotopic_mass": 73463.0 }, "refseq": { "ac": "XP_035298010", "name": "lamin tail domain-containing protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298010" }, "gene_names": [ { "name": "Lmntd2", "type": "recommended", "evidence": [ { "id": "A0A061IDR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IDR1" } ] }, { "name": "Lmntd2", "type": "synonym", "evidence": [ { "id": "XP_035298010", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298010" } ] } ], "protein_names": [ { "name": "Lamin tail domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "A0A061IDR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IDR1/entry#names_and_taxonomy" } ] }, { "name": "lamin tail domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "XP_035298010", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298010" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035298010", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298010" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IDR1", "url": "https://www.uniprot.org/uniprotkb/A0A061IDR1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Lmntd2", "url": "https://www.uniprot.org/uniprotkb/A0A061IDR1", "locus": {} } ], "crossref": [ { "id": "100774508", "url": "https://www.ncbi.nlm.nih.gov/gene/100774508", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036415", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036415", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774508", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774508", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HLTVWGE", "url": "https://omabrowser.org/oma/group/HLTVWGE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061IDR1", "url": "https://www.orthodb.org/?gene=A0A061IDR1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19956", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19956", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19956:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19956:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00932", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00932", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035298010", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298010", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IDR1", "url": "https://www.uniprot.org/uniprotkb/A0A061IDR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IDR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IDR1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPKSCQESEDEQVSPAPSGVKPDSRELESPGGTPLDTVAPSSSQSSKPYCASTPVGCSAKQQLSPETLDPCTLRLLWEQRELEIQALRWAVQNDQNARYYHILQEVAGIPPERNSKSQDKILQNQVQKLTLELKAQKEQAQLEKESLEEKLQQNLCAIQQLEAELQTFQKSCLLQLARSSWVGRMLRSQTGSVEVVTAEVLKDPSDSSEYAEVPTAGEGFRLEDVDWNSIAHRYPNLFSNMSYHSDHKLPQPQQSSEMDASDSESVKHVEKPGKSLEWSALPVVDNSSSEGTDSDYSSCQLVLHSGGKVVTGHSPQGTDLTSEQMQESTRSGSGHMEDLHKSRSPSDSKTVLEPFADLHLQYARPQLNPLGCCLKIAAVSYRERFIRILNQSQAETVDLGGFVLRQFVKDFPVCMYRFPPGTLLAPQHHITVWGEGASRTKKHLPVSSGQDPFHFQSSRGCVTMLVNPHGQVLSEHQAAPCVTLGSKIFTDNTDWSIDRFPLPESEPNADHGEERHRPSSPHKGRVQYARAMRKKPGPGVHQQRTSGLRTSGSLRPTETRDILPLLSTRKLLHLGEVPAQQEGMKTETSELLPAIPECPSRVCLEDSQGRQERKVQVCRKSVDLSCPMVALSVQNSAESRYGFRFLCYPPITEELFRRL", "length": 660, "header": "tr|A0A061IDR1-1|A0A061IDR1_CRIGR Isoform 1 of Lamin tail domain-containing protein 2 OS=Cricetulus griseus OX=10029 GN=Lmntd2 PE=4 SV=1 CANONICAL=A0A061IDR1-1" }, "isoforms": [ { "isoform_ac": "A0A061IDR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IDR1/entry#A0A061IDR1-1", "sequence": { "sequence": "MAPKSCQESEDEQVSPAPSGVKPDSRELESPGGTPLDTVAPSSSQSSKPYCASTPVGCSAKQQLSPETLDPCTLRLLWEQRELEIQALRWAVQNDQNARYYHILQEVAGIPPERNSKSQDKILQNQVQKLTLELKAQKEQAQLEKESLEEKLQQNLCAIQQLEAELQTFQKSCLLQLARSSWVGRMLRSQTGSVEVVTAEVLKDPSDSSEYAEVPTAGEGFRLEDVDWNSIAHRYPNLFSNMSYHSDHKLPQPQQSSEMDASDSESVKHVEKPGKSLEWSALPVVDNSSSEGTDSDYSSCQLVLHSGGKVVTGHSPQGTDLTSEQMQESTRSGSGHMEDLHKSRSPSDSKTVLEPFADLHLQYARPQLNPLGCCLKIAAVSYRERFIRILNQSQAETVDLGGFVLRQFVKDFPVCMYRFPPGTLLAPQHHITVWGEGASRTKKHLPVSSGQDPFHFQSSRGCVTMLVNPHGQVLSEHQAAPCVTLGSKIFTDNTDWSIDRFPLPESEPNADHGEERHRPSSPHKGRVQYARAMRKKPGPGVHQQRTSGLRTSGSLRPTETRDILPLLSTRKLLHLGEVPAQQEGMKTETSELLPAIPECPSRVCLEDSQGRQERKVQVCRKSVDLSCPMVALSVQNSAESRYGFRFLCYPPITEELFRRL", "length": 660, "header": "tr|A0A061IDR1-1|A0A061IDR1_CRIGR Isoform 1 of Lamin tail domain-containing protein 2 OS=Cricetulus griseus OX=10029 GN=Lmntd2 PE=4 SV=1 CANONICAL=A0A061IDR1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 216, "start_aa": "Thr", "end_pos": 216, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr216", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IDR1", "url": "https://www.uniprot.org/uniprotkb/A0A061IDR1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IDR1", "url": "https://www.uniprot.org/uniprotkb/A0A061IDR1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774508", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774508", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3MX93-1", "protein_name": "Lamin tail domain containing 2", "gene_name": "LMNTD2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPKSCQEAEDAEEEALASLVDREPVSGHMGPPVGAAADPVASTHPQNAKPSSTRMVSSINLSALESLDPRTLRLLWGQRELEIQALRWAIQNQREARHCRILQEVAGLPAERSSRSKDKFLQNQVQKLTLELKAQKEKAQLQEKKRLEERLQQAEDALRQLEAELQAFQKSCLLQLARSSWVGRVLRSSTGSVEVVTAETLMDLSDFSENDQAPTAGEGFRLEDVDWNSIAHRYPNLFTNLESSSDQKHPRTSQLPTASPPDQWSSELCCRHQEHNLKSVEWSSLPLAGTSSSGGADSESSNSQLAAHNRVHKVTGDPPQVPSHTAKQVEARAQSLCRDSQSPCLHSSPSPSGSCLKIMAVSRRQRFVRILNQSLEETVDLGGFVLQQLVLDFPVCMYRFPPSTLLPPRHHITVWGEGPCSTRRQQLSSLGREPVHFYSSRSCVTLLLNPQGEVLSEHQSPHCVTPVSRIFADNTDLSIDCFPLSEARPEADLAEHQPQPRPPRKGRVREARAGRRRPGWGPRVLQCRVCPGTTPSRWQAVSHDPSLARPRVQLPRLSTIKLLRQREAPVWPEDVAQTHPELLPSIPIPGESASRAPPPQVCRKRVDCGCPMVALSVQSTAESRFGFRFLSCPPITVDTRWPL", "length": 644 }, "evidence": [ { "id": "A0A061IDR1", "url": "https://omabrowser.org/oma/group/A0A061IDR1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q0VET5-1", "protein_name": "Lamin tail domain-containing protein 2", "gene_name": "Lmntd2", "tax_id": 10090, "organism": "Mus musculus", 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061IDS5-1", "uniprot_ac": "A0A061IDS5", "uniprot_id": "A0A061IDS5_CRIGR", "mass": { "chemical_mass": 50004.0, "monoisotopic_mass": 50004.0 }, "refseq": { "ac": "XP_035295102", "name": "PC-esterase domain-containing protein 1B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295102" }, "gene_names": [ { "name": "Pced1b", "type": "recommended", "evidence": [ { "id": "A0A061IDS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IDS5" } ] }, { "name": "Pced1b", "type": "synonym", "evidence": [ { "id": "XP_035295102", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295102" } ] } ], "protein_names": [ { "name": "PC-esterase domain-containing protein 1B", "type": "synonym", "evidence": [ { "id": "XP_035295102", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295102" }, { "id": "A0A061IDS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IDS5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035295102", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295102" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IDS5", "url": "https://www.uniprot.org/uniprotkb/A0A061IDS5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pced1b", "url": "https://www.uniprot.org/uniprotkb/A0A061IDS5", "locus": {} } ], "crossref": [ { "id": "100760834", "url": "https://www.ncbi.nlm.nih.gov/gene/100760834", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR036514", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036514", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760834", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760834", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061IDS5", "url": "https://www.orthodb.org/?gene=A0A061IDS5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14469", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14469", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14469:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14469:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_035295102", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035295102", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IDS5", "url": "https://www.uniprot.org/uniprotkb/A0A061IDS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IDS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IDS5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVRLLASEVQQLLHNKYVVVLGDSVHRAVYKDLVLLLQKDCLLTHKQLRTKGELTFEKDQLMKGGELDTLHNRTDYREVREFCSDHHLVRFYFLTRVYSEYMETVLEELQSGTHAPDVIIMNSCLWDVSRYGRNSLSSYRQNLESLFGRMDQVLPKSCLLVWNTAMPLGDKIKAAFLPQKCKGQYRISVATLKKRVSQANFYSHAEATKRCFDVLDLNFHFRQAKKHLQGDGVHWNEHAHRRLSYLLLAHMADAWGVELPHRDPWEPDPVAWESPGLVEEWHPQANRGPQAFAQAPPMPLPRPRPLFPPPGLPLRPPPLLSCPLPPPQATPPLPLYPQDTYFSSDHVFHSDEFYIHSEGPSPPHTGYTFEGDFSFYPQPPVPNFRPPCHQRQAPVVHRGFPRRFAHGPYTPWRERPRRPQRHAPPCLESRPQ", "length": 432, "header": "tr|A0A061IDS5-1|A0A061IDS5_CRIGR Isoform 1 of PC-esterase domain-containing protein 1B OS=Cricetulus griseus OX=10029 GN=Pced1b PE=3 SV=1 CANONICAL=A0A061IDS5-1" }, "isoforms": [ { "isoform_ac": "A0A061IDS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IDS5/entry#A0A061IDS5-1", "sequence": { "sequence": "MVRLLASEVQQLLHNKYVVVLGDSVHRAVYKDLVLLLQKDCLLTHKQLRTKGELTFEKDQLMKGGELDTLHNRTDYREVREFCSDHHLVRFYFLTRVYSEYMETVLEELQSGTHAPDVIIMNSCLWDVSRYGRNSLSSYRQNLESLFGRMDQVLPKSCLLVWNTAMPLGDKIKAAFLPQKCKGQYRISVATLKKRVSQANFYSHAEATKRCFDVLDLNFHFRQAKKHLQGDGVHWNEHAHRRLSYLLLAHMADAWGVELPHRDPWEPDPVAWESPGLVEEWHPQANRGPQAFAQAPPMPLPRPRPLFPPPGLPLRPPPLLSCPLPPPQATPPLPLYPQDTYFSSDHVFHSDEFYIHSEGPSPPHTGYTFEGDFSFYPQPPVPNFRPPCHQRQAPVVHRGFPRRFAHGPYTPWRERPRRPQRHAPPCLESRPQ", "length": 432, "header": "tr|A0A061IDS5-1|A0A061IDS5_CRIGR Isoform 1 of PC-esterase domain-containing protein 1B OS=Cricetulus griseus OX=10029 GN=Pced1b PE=3 SV=1 CANONICAL=A0A061IDS5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 330, "start_aa": "Thr", "end_pos": 330, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr330", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IDS5", "url": "https://www.uniprot.org/uniprotkb/A0A061IDS5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760834", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760834", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A061IDS5", "url": "https://www.uniprot.org/uniprotkb/A0A061IDS5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], 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"count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061IDV8-1", "uniprot_ac": "A0A061IDV8", "uniprot_id": "A0A061IDV8_CRIGR", "mass": { "chemical_mass": 95554.0, "monoisotopic_mass": 95554.0 }, "refseq": { "ac": "XP_027260626", "name": "tetratricopeptide repeat protein 13 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260626" }, "gene_names": [ { "name": "Ttc13", "type": "recommended", "evidence": [ { "id": "A0A061IDV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IDV8" } ] }, { "name": "Ttc13", "type": "synonym", "evidence": [ { "id": "XP_027260626", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260626" } ] } ], "protein_names": [ { "name": "Tetratricopeptide repeat protein 13 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A061IDV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IDV8/entry#names_and_taxonomy" } ] }, { "name": "tetratricopeptide repeat protein 13 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027260626", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260626" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027260626", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260626" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IDV8", "url": "https://www.uniprot.org/uniprotkb/A0A061IDV8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ttc13", "url": "https://www.uniprot.org/uniprotkb/A0A061IDV8", "locus": {} } ], "crossref": [ { "id": "100766190", "url": "https://www.ncbi.nlm.nih.gov/gene/100766190", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766190", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766190", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061IDV8", "url": "https://www.orthodb.org/?gene=A0A061IDV8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44523", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44523", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44523:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44523:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00515", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00515", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13432", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13432", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027260626", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260626", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IDV8", "url": "https://www.uniprot.org/uniprotkb/A0A061IDV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IDV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IDV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IET6", "url": "https://www.uniprot.org/uniprotkb/A0A061IET6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IET6-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IET6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FHP6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FHP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FHP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FHP6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FI21", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FI21-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FI21-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FIY4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FIY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FIY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FIY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FJD3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FJD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJD3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FLA7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FLA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLA7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FLJ1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FLJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FLJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FMU8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FMU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GUF1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GUF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GUF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GUF1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GVG0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GVG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVG0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GYD6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GYD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYD6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JBN8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JBN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JFI8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JFI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JFI8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJ31", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJ31-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ31-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPAGRDCGCWGGSGAGVVLSLLLLLLGALACARATEHYSPLSLLKQELQHRQQQDASAGGGCSQSGDWADQYPECESSFLNFHESDCELRGSAPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLVGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFELSRVIALEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFEQSLELNRNQPTAMLYKGLTFFHRGLLKEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQKASPEYLRVKYLREYSRYLHAHLDTPLTEYNIDTDLPGSFKDHWAKNLPFLIDGYEEQPGLQPHIKDVLHQNFEGYRPEVQEMICVADRLGSLMQYETPGFLPNKRIHRAMGLAALEVMQAVHRTWTNSKVRMNGKTRLMQWRDMFDIAVKWRRIADPDQPVLWLDQMPARSLSRGFNNHINLIRGQVINMRYLEYFEKILHFIKDRILVYHGANNPKGLLEVREALEKVHKVEDLLPIMKQFNTKTKDGFTVNTKVPSLKDQGKEYDGFTITITGDKVGNILFSVETQTTEERTQLYHAEIDALYKDLTAKGKVLILSSEFGEADAVCNLILSLVYYFYNLMPLSRGSSVIAYSVIVGALMASGKEVAGKIPKGKLVDFEAMTAPGSEAFSKIAKSWMNLKSISPSYKTLPSVSETFPTLRSMMEVLNTDSTPRCLKKL", "length": 846, "header": "tr|A0A061IDV8-1|A0A061IDV8_CRIGR Isoform 1 of Tetratricopeptide repeat protein 13 isoform X2 OS=Cricetulus griseus OX=10029 GN=Ttc13 PE=4 SV=1 CANONICAL=A0A061IDV8-1" }, "isoforms": [ { "isoform_ac": "A0A061IDV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IDV8/entry#A0A061IDV8-1", "sequence": { "sequence": "MAPAGRDCGCWGGSGAGVVLSLLLLLLGALACARATEHYSPLSLLKQELQHRQQQDASAGGGCSQSGDWADQYPECESSFLNFHESDCELRGSAPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLVGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFELSRVIALEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFEQSLELNRNQPTAMLYKGLTFFHRGLLKEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQKASPEYLRVKYLREYSRYLHAHLDTPLTEYNIDTDLPGSFKDHWAKNLPFLIDGYEEQPGLQPHIKDVLHQNFEGYRPEVQEMICVADRLGSLMQYETPGFLPNKRIHRAMGLAALEVMQAVHRTWTNSKVRMNGKTRLMQWRDMFDIAVKWRRIADPDQPVLWLDQMPARSLSRGFNNHINLIRGQVINMRYLEYFEKILHFIKDRILVYHGANNPKGLLEVREALEKVHKVEDLLPIMKQFNTKTKDGFTVNTKVPSLKDQGKEYDGFTITITGDKVGNILFSVETQTTEERTQLYHAEIDALYKDLTAKGKVLILSSEFGEADAVCNLILSLVYYFYNLMPLSRGSSVIAYSVIVGALMASGKEVAGKIPKGKLVDFEAMTAPGSEAFSKIAKSWMNLKSISPSYKTLPSVSETFPTLRSMMEVLNTDSTPRCLKKL", "length": 846, "header": "tr|A0A061IDV8-1|A0A061IDV8_CRIGR Isoform 1 of Tetratricopeptide repeat protein 13 isoform X2 OS=Cricetulus griseus OX=10029 GN=Ttc13 PE=4 SV=1 CANONICAL=A0A061IDV8-1" }, "locus": {} }, { "isoform_ac": "A0A061IET6-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IDV8/entry#A0A061IET6-1", "sequence": { "sequence": "MAPAGRDCGCWGGSGAGVVLSLLLLLLGALACARATEHYSPLSLLKQELQHRQQQDASAGGGCSQSGDWADQYPECESSFLNFHESDCELRGSAPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLVGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFEQSLELNRNQPTAMLYKGLTFFHRGLLKEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQKASPEYLRVKYLREYSRYLHAHLDTPLTEYNIDTDLPGSFKDHWAKNLPFLIDGYEEQPGLQPHIKDVLHQNFEGYRPEVQEMICVADRLGSLMQYETPGFLPNKRIHRAMGLAALEVMQAVHRTWTNSKVRMNGKTRLMQWRDMFDIAVKWRRIADPDQPVLWLDQMPARSLSRGFNNHINLIRGQVINMRYLEYFEKILHFIKDRILVYHGANNPKGLLEVREALEKVHKVEDLLPIMKQFNTKTKDGFTVNTKVPSLKDQGKEYDGFTITITGDKVGNILFSVETQTTEERTQLYHAEIDALYKDLTAKGKVLILSSEFGEADAVCNLILSLVYYFYNLMPLSRGSSVIAYSVIVGALMASGKEVAGKIPKGKLVDFEAMTAPGSEAFSKIAKSWMNLKSISPSYKTLPSVSETFPTLRSMMEVLNTDSTPRCLKKL", "length": 815, "header": "tr|A0A061IET6-1|A0A061IET6_CRIGR Computationally mapped isoform of Tetratricopeptide repeat protein 13 isoform X4 OS=Cricetulus griseus OX=10029 GN=Ttc13 PE=4 SV=1 CANONICAL=A0A061IDV8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FHP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IDV8/entry#A0A9J7FHP6-1", "sequence": { "sequence": "MAPAGRDCGCWGGSGAGVVLSLLLLLLGALACARATEHYSPLSLLKQELQHRQQQDASAGGGCSQSGDWADQYPECESSFLNFHESDCELRGSAPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLVGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFELSRVIALEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFEQSLELNRNQPTAMLYKGLTFFHRGLLKEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQKASPEYLRVKYLREYSRYLHAHLDTPLTEYNIDTDLPGSFKDHWAKNLPFLIDGYEEQPGLQPHIKDVLHQNFEGYRPEVQEMICVADRLGSLMQYETPGFLPNKRIHRAMGLAALEVMQAVHRTWTNSKVRMNGKTRLMQWRDMFDIAVKWRRIADPDQPVLWLDQMPARSLSRGFNNHINLIRGQVINMRYLEYFEKILHFIKDRILVYHGANNPKGLLEVREALEKVHKVEDLLPIMKFNTKTKDGFTVNTKVPSLKDQGKEYDGFTITITGDKVGNILFSVETQTTEERTQLYHAEIDALYKDLTAKGKVLILSSEFGEADAVCNLILSLVYYFYNLMPLSRGSSVIAYSVIVGALMASGKEVAGKIPKGKLVDFEAMTAPGSEAFSKIAKSWMNLKSISPSYKTLPSVSETFPTLRSMMEVLNTDSTPRCLKKL", "length": 845, "header": "tr|A0A9J7FHP6-1|A0A9J7FHP6_CRIGR Computationally mapped isoform of Tetratricopeptide repeat protein 13 isoform X3 OS=Cricetulus griseus OX=10029 GN=Ttc13 PE=4 SV=1 CANONICAL=A0A061IDV8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FI21-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IDV8/entry#A0A9J7FI21-1", "sequence": { "sequence": "MAPAGRDCGCWGGSGAGVVLSLLLLLLGALACARATEHYSPLSLLKQELQHRQQQDASAGGGCSQSGDWADQYPECESSFLNFHESDCELRGSAPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLVGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQKASPEYLRVKYLREYSRYLHAHLDTPLTEYNIDTDLPGSFKDHWAKNLPFLIDGYEEQPGLQPHIKDVLHQNFEGYRPEVQEMICVADRLGSLMQYETPGFLPNKRIHRAMGLAALEVMQAVHRTWTNSKVRMNGKTRLMQWRDMFDIAVKWRRIADPDQPVLWLDQMPARSLSRGFNNHINLIRGQVINMRYLEYFEKILHFIKDRILVYHGANNPKGLLEVREALEKVHKVEDLLPIMKQFNTKTKDGFTVNTKVPSLKDQGKEYDGFTITITGDKVGNILFSVETQTTEERTQLYHAEIDALYKDLTAKGKVLILSSEFGEADAVCNLILSLVYYFYNLMPLSRGSSVIAYSVIVGALMASGKEVAGKIPKGKLVDFEAMTAPGSEAFSKIAKSWMNLKSISPSYKTLPSVSETFPTLRSMMEVLNTDSTPRCLKKL", "length": 739, "header": "tr|A0A9J7FI21-1|A0A9J7FI21_CRIGR Computationally mapped isoform of Tetratricopeptide repeat protein 13 isoform X12 OS=Cricetulus griseus OX=10029 GN=Ttc13 PE=4 SV=1 CANONICAL=A0A061IDV8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FIY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IDV8/entry#A0A9J7FIY4-1", "sequence": { "sequence": "MAPAGRDCGCWGGSGAGVVLSLLLLLLGALACARATEHYSPLSLLKQELQHRQQQDASAGGGCSQSGDWADQYPECESSFLNFHESDCELRGSAPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLVGSGLYDEAIRHFSTMLQEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQKASPEYLRVKYLREYSRYLHAHLDTPLTEYNIDTDLPGSFKDHWAKNLPFLIDGYEEQPGLQPHIKDVLHQNFEGYRPEVQEMICVADRLGSLMQYETPGFLPNKRIHRAMGLAALEVMQAVHRTWTNSKVRMNGKTRLMQWRDMFDIAVKWRRIADPDQPVLWLDQMPARSLSRGFNNHINLIRGQVINMRYLEYFEKILHFIKDRILVYHGANNPKGLLEVREALEKVHKVEDLLPIMKFNTKTKDGFTVNTKVPSLKDQGKEYDGFTITITGDKVGNILFSVETQTTEERTQLYHAEIDALYKDLTAKGKVLILSSEFGEADAVCNLILSLVYYFYNLMPLSRGSSVIAYSVIVGALMASGKEVAGKIPKGKLVDFEAMTAPGSEAFSKIAKSWMNLKSISPSYKTLPSVSETFPTLRSMMEVLNTDSTPRCLKKL", "length": 716, "header": "tr|A0A9J7FIY4-1|A0A9J7FIY4_CRIGR Computationally mapped isoform of Tetratricopeptide repeat protein 13 isoform X15 OS=Cricetulus griseus OX=10029 GN=Ttc13 PE=4 SV=1 CANONICAL=A0A061IDV8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FJD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IDV8/entry#A0A9J7FJD3-1", "sequence": { "sequence": "MAPAGRDCGCWGGSGAGVVLSLLLLLLGALACARATEHYSPLSLLKQELQHRQQQDASAGGGCSQSGDWADQYPECESSFLNFHESDCELRGSAPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLVGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFELSRVIALEPDRPEVFEQRAEEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQKASPEYLRVKYLREYSRYLHAHLDTPLTEYNIDTDLPGSFKDHWAKNLPFLIDGYEEQPGLQPHIKDVLHQNFEGYRPEVQEMICVADRLGSLMQYETPGFLPNKRIHRAMGLAALEVMQAVHRTWTNSKVRMNGKTRLMQWRDMFDIAVKWRRIADPDQPVLWLDQMPARSLSRGFNNHINLIRGQVINMRYLEYFEKILHFIKDRILVYHGANNPKGLLEVREALEKVHKVEDLLPIMKQFNTKTKDGFTVNTKVPSLKDQGKEYDGFTITITGDKVGNILFSVETQTTEERTQLYHAEIDALYKDLTAKGKVLILSSEFGEADAVCNLILSLVYYFYNLMPLSRGSSVIAYSVIVGALMASGKEVAGKIPKGKLVDFEAMTAPGSEAFSKIAKSWMNLKSISPSYKTLPSVSETFPTLRSMMEVLNTDSTPRCLKKL", "length": 770, "header": "tr|A0A9J7FJD3-1|A0A9J7FJD3_CRIGR Computationally mapped isoform of Tetratricopeptide repeat protein 13 isoform X9 OS=Cricetulus griseus OX=10029 GN=Ttc13 PE=4 SV=1 CANONICAL=A0A061IDV8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FLA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IDV8/entry#A0A9J7FLA7-1", "sequence": { "sequence": "MAPAGRDCGCWGGSGAGVVLSLLLLLLGALACARATEHYSPLSLLKQELQHRQQQDASAGGGCSQSGDWADQYPECAIAYVLVGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFELSRVIALEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFEQSLELNRNQPTAMLYKGLTFFHRGLLKEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQKASPEYLRVKYLREYSRYLHAHLDTPLTEYNIDTDLPGSFKDHWAKNLPFLIDGYEEQPGLQPHIKDVLHQNFEGYRPEVQEMICVADRLGSLMQYETPGFLPNKRIHRAMGLAALEVMQAVHRTWTNSKVRMNGKTRLMQWRDMFDIAVKWRRIADPDQPVLWLDQMPARSLSRGFNNHINLIRGQVINMRYLEYFEKILHFIKDRILVYHGANNPKGLLEVREALEKVHKVEDLLPIMKQFNTKTKDGFTVNTKVPSLKDQGKEYDGFTITITGDKVGNILFSVETQTTEERTQLYHAEIDALYKDLTAKGKVLILSSEFGEADAVCNLILSLVYYFYNLMPLSRGSSVIAYSVIVGALMASGKEVAGKIPKGKLVDFEAMTAPGSEAFSKIAKSWMNLKSISPSYKTLPSVSETFPTLRSMMEVLNTDSTPRCLKKL", "length": 789, "header": "tr|A0A9J7FLA7-1|A0A9J7FLA7_CRIGR Computationally mapped isoform of Tetratricopeptide repeat protein 13 isoform X8 OS=Cricetulus griseus OX=10029 GN=Ttc13 PE=4 SV=1 CANONICAL=A0A061IDV8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FLJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IDV8/entry#A0A9J7FLJ1-1", "sequence": { "sequence": "MAPAGRDCGCWGGSGAGVVLSLLLLLLGALACARATEHYSPLSLLKQELQHRQQQDASAGGGCSQSGDWADQYPECESSFLNFHESDCELRGSAPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLVGSGLYDEAIRHFSTMLQILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFEQSLELNRNQPTAMLYKGLTFFHRGLLKEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQKASPEYLRVKYLREYSRYLHAHLDTPLTEYNIDTDLPGSFKDHWAKNLPFLIDGYEEQPGLQPHIKDVLHQNFEGYRPEVQEMICVADRLGSLMQYETPGFLPNKRIHRAMGLAALEVMQAVHRTWTNSKVRMNGKTRLMQWRDMFDIAVKWRRIADPDQPVLWLDQMPARSLSRGFNNHINLIRGQVINMRYLEYFEKILHFIKDRILVYHGANNPKGLLEVREALEKVHKVEDLLPIMKFNTKTKDGFTVNTKVPSLKDQGKEYDGFTITITGDKVGNILFSVETQTTEERTQLYHAEIDALYKDLTAKGKVLILSSEFGEADAVCNLILSLVYYFYNLMPLSRGSSVIAYSVIVGALMASGKEVAGKIPKGKLVDFEAMTAPGSEAFSKIAKSWMNLKSISPSYKTLPSVSETFPTLRSMMEVLNTDSTPRCLKKL", "length": 792, "header": "tr|A0A9J7FLJ1-1|A0A9J7FLJ1_CRIGR Computationally mapped isoform of Tetratricopeptide repeat protein 13 isoform X7 OS=Cricetulus griseus OX=10029 GN=Ttc13 PE=4 SV=1 CANONICAL=A0A061IDV8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FMU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IDV8/entry#A0A9J7FMU8-1", "sequence": { "sequence": "MAPAGRDCGCWGGSGAGVVLSLLLLLLGALACARATEHYSPLSLLKQELQHRQQQDASAGGGCSQSGDWADQYPECESSFLNFHESDCELRGSAPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLVGSGLYDEAIRHFSTMLQDYATAHEDFEQSLELNRNQPTAMLYKGLTFFHRGLLKEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQKASPEYLRVKYLREYSRYLHAHLDTPLTEYNIDTDLPGSFKDHWAKNLPFLIDGYEEQPGLQPHIKDVLHQNFEGYRPEVQEMICVADRLGSLMQYETPGFLPNKRIHRAMGLAALEVMQAVHRTWTNSKVRMNGKTRLMQWRDMFDIAVKWRRIADPDQPVLWLDQMPARSLSRGFNNHINLIRGQVINMRYLEYFEKILHFIKDRILVYHGANNPKGLLEVREALEKVHKVEDLLPIMKQFNTKTKDGFTVNTKVPSLKDQGKEYDGFTITITGDKVGNILFSVETQTTEERTQLYHAEIDALYKDLTAKGKVLILSSEFGEADAVCNLILSLVYYFYNLMPLSRGSSVIAYSVIVGALMASGKEVAGKIPKGKLVDFEAMTAPGSEAFSKIAKSWMNLKSISPSYKTLPSVSETFPTLRSMMEVLNTDSTPRCLKKL", "length": 754, "header": "tr|A0A9J7FMU8-1|A0A9J7FMU8_CRIGR Computationally mapped isoform of Tetratricopeptide repeat protein 13 isoform X11 OS=Cricetulus griseus OX=10029 GN=Ttc13 PE=4 SV=1 CANONICAL=A0A061IDV8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GUF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IDV8/entry#A0A9J7GUF1-1", "sequence": { "sequence": "MAPAGRDCGCWGGSGAGVVLSLLLLLLGALACARATEHYSPLSLLKQELQHRQQQDASAGGGCSQSGDWADQYPECESSFLNFHESDCELRGSAPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLVGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFEQSLELNRNQPTAMLYKGLTFFHRGLLKEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQKASPEYLRVKYLREYSRYLHAHLDTPLTEYNIDTDLPGSFKDHWAKNLPFLIDGYEEQPGLQPHIKDVLHQNFEGYRPEVQEMICVADRLGSLMQYETPGFLPNKRIHRAMGLAALEVMQAVHRTWTNSKVRMNGKTRLMQWRDMFDIAVKWRRIADPDQPVLWLDQMPARSLSRGFNNHINLIRGQVINMRYLEYFEKILHFIKDRILVYHGANNPKGLLEVREALEKVHKVEDLLPIMKFNTKTKDGFTVNTKVPSLKDQGKEYDGFTITITGDKVGNILFSVETQTTEERTQLYHAEIDALYKDLTAKGKVLILSSEFGEADAVCNLILSLVYYFYNLMPLSRGSSVIAYSVIVGALMASGKEVAGKIPKGKLVDFEAMTAPGSEAFSKIAKSWMNLKSISPSYKTLPSVSETFPTLRSMMEVLNTDSTPRCLKKL", "length": 814, "header": "tr|A0A9J7GUF1-1|A0A9J7GUF1_CRIGR Computationally mapped isoform of Tetratricopeptide repeat protein 13 isoform X5 OS=Cricetulus griseus OX=10029 GN=Ttc13 PE=4 SV=1 CANONICAL=A0A061IDV8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GVG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IDV8/entry#A0A9J7GVG0-1", "sequence": { "sequence": "MAPAGRDCGCWGGSGAGVVLSLLLLLLGALACARATEHYSPLSLLKQELQHRQQQDASAGGGCSQSGDWADQYPECESSFLNFHESDCELRGSAPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLVGSGLYDEAIRHFSTMLQEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQKASPEYLRVKYLREYSRYLHAHLDTPLTEYNIDTDLPGSFKDHWAKNLPFLIDGYEEQPGLQPHIKDVLHQNFEGYRPEVQEMICVADRLGSLMQYETPGFLPNKRIHRAMGLAALEVMQAVHRTWTNSKVRMNGKTRLMQWRDMFDIAVKWRRIADPDQPVLWLDQMPARSLSRGFNNHINLIRGQVINMRYLEYFEKILHFIKDRILVYHGANNPKGLLEVREALEKVHKVEDLLPIMKQFNTKTKDGFTVNTKVPSLKDQGKEYDGFTITITGDKVGNILFSVETQTTEERTQLYHAEIDALYKDLTAKGKVLILSSEFGEADAVCNLILSLVYYFYNLMPLSRGSSVIAYSVIVGALMASGKEVAGKIPKGKLVDFEAMTAPGSEAFSKIAKSWMNLKSISPSYKTLPSVSETFPTLRSMMEVLNTDSTPRCLKKL", "length": 717, "header": "tr|A0A9J7GVG0-1|A0A9J7GVG0_CRIGR Computationally mapped isoform of Tetratricopeptide repeat protein 13 isoform X14 OS=Cricetulus griseus OX=10029 GN=Ttc13 PE=4 SV=1 CANONICAL=A0A061IDV8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GYD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IDV8/entry#A0A9J7GYD6-1", "sequence": { "sequence": "MAPAGRDCGCWGGSGAGVVLSLLLLLLGALACARATEHYSPLSLLKQELQHRQQQDASAGGGCSQSGDWADQYPECESSFLNFHESDCELRGSAPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLVGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFELSRVIALEPDRPEVFEQRAEEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQKASPEYLRVKYLREYSRYLHAHLDTPLTEYNIDTDLPGSFKDHWAKNLPFLIDGYEEQPGLQPHIKDVLHQNFEGYRPEVQEMICVADRLGSLMQYETPGFLPNKRIHRAMGLAALEVMQAVHRTWTNSKVRMNGKTRLMQWRDMFDIAVKWRRIADPDQPVLWLDQMPARSLSRGFNNHINLIRGQVINMRYLEYFEKILHFIKDRILVYHGANNPKGLLEVREALEKVHKVEDLLPIMKFNTKTKDGFTVNTKVPSLKDQGKEYDGFTITITGDKVGNILFSVETQTTEERTQLYHAEIDALYKDLTAKGKVLILSSEFGEADAVCNLILSLVYYFYNLMPLSRGSSVIAYSVIVGALMASGKEVAGKIPKGKLVDFEAMTAPGSEAFSKIAKSWMNLKSISPSYKTLPSVSETFPTLRSMMEVLNTDSTPRCLKKL", "length": 769, "header": "tr|A0A9J7GYD6-1|A0A9J7GYD6_CRIGR Computationally mapped isoform of Tetratricopeptide repeat protein 13 isoform X10 OS=Cricetulus griseus OX=10029 GN=Ttc13 PE=4 SV=1 CANONICAL=A0A061IDV8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JBN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IDV8/entry#A0A9J7JBN8-1", "sequence": { "sequence": "MAPAGRDCGCWGGSGAGVVLSLLLLLLGALACARATEHYSPLSLLKQELQHRQQQDASAGGGCSQSGDWADQYPECAIAYVLVGSGLYDEAIRHFSTMLQDYATAHEDFEQSLELNRNQPTAMLYKGLTFFHRGLLKEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQKASPEYLRVKYLREYSRYLHAHLDTPLTEYNIDTDLPGSFKDHWAKNLPFLIDGYEEQPGLQPHIKDVLHQNFEGYRPEVQEMICVADRLGSLMQYETPGFLPNKRIHRAMGLAALEVMQAVHRTWTNSKVRMNGKTRLMQWRDMFDIAVKWRRIADPDQPVLWLDQMPARSLSRGFNNHINLIRGQVINMRYLEYFEKILHFIKDRILVYHGANNPKGLLEVREALEKVHKVEDLLPIMKQFNTKTKDGFTVNTKVPSLKDQGKEYDGFTITITGDKVGNILFSVETQTTEERTQLYHAEIDALYKDLTAKGKVLILSSEFGEADAVCNLILSLVYYFYNLMPLSRGSSVIAYSVIVGALMASGKEVAGKIPKGKLVDFEAMTAPGSEAFSKIAKSWMNLKSISPSYKTLPSVSETFPTLRSMMEVLNTDSTPRCLKKL", "length": 697, "header": "tr|A0A9J7JBN8-1|A0A9J7JBN8_CRIGR Computationally mapped isoform of Tetratricopeptide repeat protein 13 isoform X16 OS=Cricetulus griseus OX=10029 GN=Ttc13 PE=4 SV=1 CANONICAL=A0A061IDV8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JFI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IDV8/entry#A0A9J7JFI8-1", "sequence": { "sequence": "MAPAGRDCGCWGGSGAGVVLSLLLLLLGALACARATEHYSPLSLLKQELQHRQQQDASAGGGCSQSGDWADQYPECAIAYVLVGSGLYDEAIRHFSTMLQILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFEQSLELNRNQPTAMLYKGLTFFHRGLLKEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQKASPEYLRVKYLREYSRYLHAHLDTPLTEYNIDTDLPGSFKDHWAKNLPFLIDGYEEQPGLQPHIKDVLHQNFEGYRPEVQEMICVADRLGSLMQYETPGFLPNKRIHRAMGLAALEVMQAVHRTWTNSKVRMNGKTRLMQWRDMFDIAVKWRRIADPDQPVLWLDQMPARSLSRGFNNHINLIRGQVINMRYLEYFEKILHFIKDRILVYHGANNPKGLLEVREALEKVHKVEDLLPIMKQFNTKTKDGFTVNTKVPSLKDQGKEYDGFTITITGDKVGNILFSVETQTTEERTQLYHAEIDALYKDLTAKGKVLILSSEFGEADAVCNLILSLVYYFYNLMPLSRGSSVIAYSVIVGALMASGKEVAGKIPKGKLVDFEAMTAPGSEAFSKIAKSWMNLKSISPSYKTLPSVSETFPTLRSMMEVLNTDSTPRCLKKL", "length": 736, "header": "tr|A0A9J7JFI8-1|A0A9J7JFI8_CRIGR Computationally mapped isoform of Tetratricopeptide repeat protein 13 isoform X13 OS=Cricetulus griseus OX=10029 GN=Ttc13 PE=4 SV=1 CANONICAL=A0A061IDV8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JJ31-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IDV8/entry#A0A9J7JJ31-1", "sequence": { "sequence": "MAPAGRDCGCWGGSGAGVVLSLLLLLLGALACARATEHYSPLSLLKQELQHRQQQDASAGGGCSQSGDWADQYPECESSFLNFHESDCELRGSAPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLVGSGLYDEAIRHFSTMLQILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFEQSLELNRNQPTAMLYKGLTFFHRGLLKEAIEAFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQKASPEYLRVKYLREYSRYLHAHLDTPLTEYNIDTDLPGSFKDHWAKNLPFLIDGYEEQPGLQPHIKDVLHQNFEGYRPEVQEMICVADRLGSLMQYETPGFLPNKRIHRAMGLAALEVMQAVHRTWTNSKVRMNGKTRLMQWRDMFDIAVKWRRIADPDQPVLWLDQMPARSLSRGFNNHINLIRGQVINMRYLEYFEKILHFIKDRILVYHGANNPKGLLEVREALEKVHKVEDLLPIMKQFNTKTKDGFTVNTKVPSLKDQGKEYDGFTITITGDKVGNILFSVETQTTEERTQLYHAEIDALYKDLTAKGKVLILSSEFGEADAVCNLILSLVYYFYNLMPLSRGSSVIAYSVIVGALMASGKEVAGKIPKGKLVDFEAMTAPGSEAFSKIAKSWMNLKSISPSYKTLPSVSETFPTLRSMMEVLNTDSTPRCLKKL", "length": 793, "header": "tr|A0A9J7JJ31-1|A0A9J7JJ31_CRIGR Computationally mapped isoform of Tetratricopeptide repeat protein 13 isoform X6 OS=Cricetulus griseus OX=10029 GN=Ttc13 PE=4 SV=1 CANONICAL=A0A061IDV8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IDV8", "url": "https://www.uniprot.org/uniprotkb/A0A061IDV8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IDV8", "url": "https://www.uniprot.org/uniprotkb/A0A061IDV8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766190", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766190", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 126, "end_pos": 128, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { 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"isoform_ac": "A0A061IEL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IEL8/entry#A0A061IEL8-1", "sequence": { "sequence": "MAETKDPIQLRLLSLELLKQLWAGHDAMCRSVARAVSEPKQDCSNSSNLEMSLSQESSCTSSVAPSSQDKRHVWNSLDNHRGNTADTSWYDKENSRVNSIPPATCQHPEPQNGLWPPSVPLLAPEAVKGPPKGMGPQKTQVPKSVLSRPSKPSKPKVTFSQESVMPESSRRFLPYLGYDWIAGSLDSNSPVTSKPDAFFSELQRFRETNKEDCICDSPEAVFPGLQESSCMEGDHECVYCYRVNRRLFPVPVDLGTTCRLCGISRDQQGPETLAEPSQVRVSIPLSILDPPHQYRIHRRKSFDASDTLALPQHCLLGWDILPPKSEKSSVPKSLDLWSSVSCEGAQRRHLSATSSSLLGGSRVCPNLGGWCPGGTDPIKMGAQALTRCPSNFGTHCCLPHSTQEGGPHSKVQEEWRLILGPTCP", "length": 424, "header": "tr|A0A061IEL8-1|A0A061IEL8_CRIGR Isoform 1 of Migration and invasion-inhibitory protein isoform X1 OS=Cricetulus griseus OX=10029 GN=Miip PE=4 SV=1 CANONICAL=A0A061IEL8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FBE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IEL8/entry#A0A9J7FBE2-1", "sequence": { "sequence": "MAETKDPIQLRLLSLELLKQLWAGHDAMCRSVARAVSEPKQDCSNSSNLEMSLSQESSCTSSVAPSSQDKRHVWNSLDNHRGNTADTSWYDKENSRVNSIPPATCQHPEPQNGLWPPSVPLLAPEAVKGPPKGMGPQKTQVPKSVLSRPSKPSKPKVTFSQESVMPESSRRFLPYLGYDWIAGSLDSNSPVTSKPDAFFSELQRFRETNKEDCICDSPEAVFPGLQESSCMEGDHECVYCYRVNRRLFPVPVDLGTTCRLCGISRDQQGPETLAEPSQVRVSIPLSILDPPHQYRIHRRKSFDASDTLALPQHCLLGWDILPPKSEKSSVPKSLDLWSSVSCEGAQRRHLSATSSSLLGGSRDFPAQVPPPIWSEPRVPQFRPSH", "length": 385, "header": "tr|A0A9J7FBE2-1|A0A9J7FBE2_CRIGR Computationally mapped isoform of Migration and invasion-inhibitory protein isoform X3 OS=Cricetulus griseus OX=10029 GN=Miip PE=4 SV=1 CANONICAL=A0A061IEL8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J7W5-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IEL8/entry#A0A9J7J7W5-1", "sequence": { "sequence": "MSLSQESSCTSSVAPSSQDKRHVWNSLDNHRGNTADTSWYDKENSRVNSIPPATCQHPEPQNGLWPPSVPLLAPEAVKGPPKGMGPQKTQVPKSVLSRPSKPSKPKVTFSQESVMPESSRRFLPYLGYDWIAGSLDSNSPVTSKPDAFFSELQRFRETNKEDCICDSPEAVFPGLQESSCMEGDHECVYCYRVNRRLFPVPVDLGTTCRLCGISRDQQGPETLAEPSQVRVSIPLSILDPPHQYRIHRRKSFDASDTLALPQHCLLGWDILPPKSEKSSVPKSLDLWSSVSCEGAQRRHLSATSSSLLGGSRVCPNLGGWCPGGTDPIKMGAQALTRCPSNFGTHCCLPHSTQEGGPHSKVQEEWRLILGPTCP", "length": 374, "header": "tr|A0A9J7J7W5-1|A0A9J7J7W5_CRIGR Computationally mapped isoform of Migration and invasion-inhibitory protein isoform X5 OS=Cricetulus griseus OX=10029 GN=Miip PE=4 SV=1 CANONICAL=A0A061IEL8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JB57-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IEL8/entry#A0A9J7JB57-1", "sequence": { "sequence": "MAETKDPIQLRLLSLELLKQLWAGHDAMCRSVARAVSEPKQDCSNSSNLEMSLSQESSCTSSVAPSSQDKRHVWNSLDNHRGNTADTSWYDKENSRVNSIPPATCQHPEPQNGLWPPSVPLLAPEAVKGPPKGMGPQKTQVPKSVLSRPSKPSKPKVTFSQESVMPESSRRFLPYLGYDWIAGSLDSNSPVTSKPDAFFSELQRFRETNKEDCICDSPEAVFPGLQESSCMEGDHELPVDLGTTCRLCGISRDQQGPETLAEPSQVRVSIPLSILDPPHQYRIHRRKSFDASDTLALPQHCLLGWDILPPKSEKSSVPKSLDLWSSVSCEGAQRRHLSATSSSLLGGSRVCPNLGGWCPGGTDPIKMGAQALTRCPSNFGTHCCLPHSTQEGGPHSKVQEEWRLILGPTCP", "length": 411, "header": "tr|A0A9J7JB57-1|A0A9J7JB57_CRIGR Computationally mapped isoform of Migration and invasion-inhibitory protein isoform X2 OS=Cricetulus griseus OX=10029 GN=Miip PE=4 SV=1 CANONICAL=A0A061IEL8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K126-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IEL8/entry#A0A9J7K126-1", "sequence": { "sequence": "MAETKDPIQLRLLSLELLKQLWAGHDAMCRSVARAVSEPKQDCSNSSNLEMSLSQESSCTSSVAPSSQDKRHVWNSLDNHRGNTADTSWYDKENSRVNSIPPATCQHPEPQNGLWPPSVPLLAPEAVKGPPKGMGPQKTQVPKSVLSRPSKPSKPKVTFSQESVMPESSRRFLPYLGYDWIAGSLDSNSPVTSKPDAFFSELQRFRETNKEDCICDSPEAVFPGLQESSCMEGDHECVYCYRVNRRLFPVPVDLGTTCRLCGISRDQQGPETLAEPSQVRVSIPLSILDPPHQYRIHRRKSFDASDTLALPQDFPAQVPPPIWSEPRVPQFRPSH", "length": 335, "header": "tr|A0A9J7K126-1|A0A9J7K126_CRIGR Computationally mapped isoform of Migration and invasion-inhibitory protein isoform X4 OS=Cricetulus griseus OX=10029 GN=Miip PE=4 SV=1 CANONICAL=A0A061IEL8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IEL8", "url": "https://www.uniprot.org/uniprotkb/A0A061IEL8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763559", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763559", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of cell migration", "id": "GO:0030336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030336", "evidence": [ { "database": "UniProtKB", "id": "A0A061IEL8", "url": "https://www.uniprot.org/uniprotkb/A0A061IEL8" } ], "pmid": "" }, { "name": "negative regulation of G2/M transition of mitotic cell cycle", "id": "GO:0010972", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010972", "evidence": [ { "database": "UniProtKB", "id": "A0A061IEL8", "url": "https://www.uniprot.org/uniprotkb/A0A061IEL8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 45, "end_pos": 47 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"uniprot_ac": "A0A061IEN1", "uniprot_id": "A0A061IEN1_CRIGR", "mass": { "chemical_mass": 14693.0, "monoisotopic_mass": 14693.0 }, "refseq": { "ac": "XP_007648951", "name": "putative protein T-ENOL isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007648951" }, "gene_names": [ { "name": "LOC100754044", "type": "recommended", "evidence": [ { "id": "A0A061IEN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IEN1" } ] }, { "name": "LOC100754044", "type": "synonym", "evidence": [ { "id": "XP_007648951", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007648951" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A061IEN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IEN1/entry#names_and_taxonomy" } ] }, { "name": "putative protein T-ENOL isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007648951", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007648951" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614830.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007648951", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007648951" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IEN1", "url": "https://www.uniprot.org/uniprotkb/A0A061IEN1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100754044", "url": "https://www.uniprot.org/uniprotkb/A0A061IEN1", "locus": {} } ], "crossref": [ { "id": "100754044", "url": "https://www.ncbi.nlm.nih.gov/gene/100754044", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "cge:100754044", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754044", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061IEN1", "url": "https://www.orthodb.org/?gene=A0A061IEN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FKY1", "url": "https://www.orthodb.org/?gene=A0A9J7FKY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FL66", "url": "https://www.orthodb.org/?gene=A0A9J7FL66", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "XP_007648951", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007648951", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IEN1", "url": "https://www.uniprot.org/uniprotkb/A0A061IEN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IEN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IEN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FKY1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FKY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FL66", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FL66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FL66-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FL66-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASTSARNGDTKDSWPPQTPASLGGGQKVSLSRSEEFLSQISAELTDEALFIARSYMNSVPIKEKQTKDQGTQISRHALTEIEPAARHTFYHLLVKSTVLECSTEQNKAPALQKWEMKDEWWEDREPSPTA", "length": 131, "header": "tr|A0A061IEN1-1|A0A061IEN1_CRIGR Isoform 1 of Uncharacterized protein OS=Cricetulus griseus OX=10029 GN=LOC100754044 PE=4 SV=1 CANONICAL=A0A061IEN1-1" }, "isoforms": [ { "isoform_ac": "A0A061IEN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IEN1/entry#A0A061IEN1-1", "sequence": { "sequence": "MASTSARNGDTKDSWPPQTPASLGGGQKVSLSRSEEFLSQISAELTDEALFIARSYMNSVPIKEKQTKDQGTQISRHALTEIEPAARHTFYHLLVKSTVLECSTEQNKAPALQKWEMKDEWWEDREPSPTA", "length": 131, "header": "tr|A0A061IEN1-1|A0A061IEN1_CRIGR Isoform 1 of Uncharacterized protein OS=Cricetulus griseus OX=10029 GN=LOC100754044 PE=4 SV=1 CANONICAL=A0A061IEN1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FKY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IEN1/entry#A0A9J7FKY1-1", "sequence": { "sequence": "MASTSARNGDTKDSWPPQTPASLGGGQKVSLSRSEEFLSQISAELTDEALFIARSYMNSVPIKEKQTKDQGTQISRHALTEIEPAARHTFYHLLVKREPSPTA", "length": 103, "header": "tr|A0A9J7FKY1-1|A0A9J7FKY1_CRIGR Computationally mapped isoform of Uncharacterized protein OS=Cricetulus griseus OX=10029 GN=LOC100754044 PE=4 SV=1 CANONICAL=A0A061IEN1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FL66-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IEN1/entry#A0A9J7FL66-1", "sequence": { "sequence": "MASTSARNGDTKDSWPPQTPASLGGGQKVSLSRSEEFLSQISAELTDEALFIARSYMNSVPIKEKQTKDQGTQISRHVFFNKSRGTDTRSDRNRTRSKAHLLPSPREKGALPNSLTTGG", "length": 119, "header": "tr|A0A9J7FL66-1|A0A9J7FL66_CRIGR Computationally mapped isoform of Uncharacterized protein OS=Cricetulus griseus OX=10029 GN=LOC100754044 PE=4 SV=1 CANONICAL=A0A061IEN1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613950.1) and transcript sequence (IACG01047011.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_016831490.1. 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OX=10029 GN=Caap1 PE=4 SV=1 CANONICAL=A0A061IEQ6-1" }, "isoforms": [ { "isoform_ac": "A0A061IEQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IEQ6/entry#A0A061IEQ6-1", "sequence": { "sequence": "MTGKKSSREKRRKRSGQEAAAALAAPDLVPVLGGTAGGCGSGGCCGGAGGGASVAGGAERSERRKRRSTDSSSSVSGSLQQETKYLLPTLEKELLLAEHSDVEEGGLDLAVSLKPVSFYISDKKEMLQQCFCIIGEKKLQKMLPDVLKNCSVEEIKKLCQEQLELLSEKKILKILEGDNGLDTDMEEEADDGCKVASDLISQQDACVDSTSSLRENKQPEGLESKQVSKRLKYYLSSYPGKGEDSDVLSINADAYDSDIEGPCNEDAAAATATAAAVATPASAPEVPERTVRSEAGQIDDLEKDIEKSVNEILGLAESSPKEPKAATLTVPPPEDVQPSAQQLELLELEMRARAIKALMKAGDIKKPV", "length": 368, "header": "tr|A0A061IEQ6-1|A0A061IEQ6_CRIGR Isoform 1 of Caspase activity and apoptosis inhibitor 1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Caap1 PE=4 SV=1 CANONICAL=A0A061IEQ6-1" }, "locus": {} }, { "isoform_ac": "A0A061IHB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IEQ6/entry#A0A061IHB5-1", "sequence": { "sequence": "MTGKKSSREKRRKRSGQEAAAALAAPDLVPVLGGTAGGCGSGGCCGGAGGGASVAGGAERSERRKRRSTDSSSSVSGSLQQETKYLLPTLEKELLLAEHSDVEEGGLDLAVSLKPVSFYISDKKEMLQQCFCIIGEKKLQKMLPDVLKNCSVEEIKKLCQEQLELLSEKKILKILEGDNGLDTDMEEEADDGCKVASDLISQQDACVDSTSSLRENKQPEGLESKQGKGEDSDVLSINADAYDSDIEGPCNEDAAAATATAAAVATPASAPEVPERTVRSEAGQIDDLEKDIEKSVNEILGLAESSPKEPKAATLTVPPPEDVQPSAQQLELLELEMRARAIKALMKAGDIKKPV", "length": 355, "header": "tr|A0A061IHB5-1|A0A061IHB5_CRIGR Computationally mapped isoform of Caspase activity and apoptosis inhibitor 1 isoform X4 OS=Cricetulus griseus OX=10029 GN=Caap1 PE=4 SV=1 CANONICAL=A0A061IEQ6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 279, "start_aa": "Thr", "end_pos": 279, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr279", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IEQ6", "url": "https://www.uniprot.org/uniprotkb/A0A061IEQ6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766887", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766887", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "A0A061IEQ6", "url": "https://www.uniprot.org/uniprotkb/A0A061IEQ6" } ], "pmid": "" }, { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A061IEQ6", "url": "https://www.uniprot.org/uniprotkb/A0A061IEQ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 149, "end_pos": 151, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 279 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 149, "end_pos": 151 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027265377", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265377" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IER7", "url": "https://www.uniprot.org/uniprotkb/A0A061IER7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100760697", "url": "https://www.uniprot.org/uniprotkb/A0A061IER7", "locus": {} } ], "crossref": [ { "id": "cd05834", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05834", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100760697", "url": "https://www.ncbi.nlm.nih.gov/gene/100760697", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000313", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000313", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760697", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760697", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061IER7", "url": "https://www.orthodb.org/?gene=A0A061IER7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12550", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12550", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12550:SF81", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12550:SF81", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027265377", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265377", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IER7", "url": "https://www.uniprot.org/uniprotkb/A0A061IER7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IER7-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IER7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSYFSHPKYKTGDLVFAKLKGYAHWPARIEQVAEPNRYQVFFFGTHETALLGPKHLFPYEESKERFGKPNKRRGFSEGLWEIEHDPMVEASPSLCSGEEQGCDQGPGLRDEPEPGLEPESLCELEPGPEPETVSEQQPGPQPAYGLLDAAAEEEPGLGEEAEAGDQHAEAEAEAKEPRHLKRSAGEQTQDAPKRPREAAPGPLEVEPSGEREAEACPIIEEPDQPQEQRPPLEEEATDQEAPLIGGEIEGL", "length": 251, "header": "tr|A0A061IER7-1|A0A061IER7_CRIGR Isoform 1 of Hepatoma-derived growth factor-like protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100760697 PE=4 SV=1 CANONICAL=A0A061IER7-1" }, "isoforms": [ { "isoform_ac": "A0A061IER7-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IER7/entry#A0A061IER7-1", "sequence": { "sequence": "MSYFSHPKYKTGDLVFAKLKGYAHWPARIEQVAEPNRYQVFFFGTHETALLGPKHLFPYEESKERFGKPNKRRGFSEGLWEIEHDPMVEASPSLCSGEEQGCDQGPGLRDEPEPGLEPESLCELEPGPEPETVSEQQPGPQPAYGLLDAAAEEEPGLGEEAEAGDQHAEAEAEAKEPRHLKRSAGEQTQDAPKRPREAAPGPLEVEPSGEREAEACPIIEEPDQPQEQRPPLEEEATDQEAPLIGGEIEGL", "length": 251, "header": "tr|A0A061IER7-1|A0A061IER7_CRIGR Isoform 1 of Hepatoma-derived growth factor-like protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100760697 PE=4 SV=1 CANONICAL=A0A061IER7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IER7", "url": "https://www.uniprot.org/uniprotkb/A0A061IER7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IER7", "url": "https://www.uniprot.org/uniprotkb/A0A061IER7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760697", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760697", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061IER7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IER7" }, { "id": "PS50812", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50812" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PWWP", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 62, "start_aa": "Thr", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061IET3-1", "uniprot_ac": "A0A061IET3", "uniprot_id": "A0A061IET3_CRIGR", "mass": { "chemical_mass": 66348.0, "monoisotopic_mass": 66348.0 }, "refseq": { "ac": "XP_003501953", "name": "podocan-like protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501953" }, "gene_names": [ { "name": "Podnl1", "type": "recommended", "evidence": [ { "id": "A0A061IET3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IET3" } ] }, { "name": "Podnl1", "type": "synonym", "evidence": [ { "id": "XP_003501953", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501953" } ] } ], "protein_names": [ { "name": "Podocan-like protein 1", "type": "synonym", "evidence": [ { "id": "A0A061IET3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IET3/entry#names_and_taxonomy" } ] }, { "name": "podocan-like protein 1", "type": "synonym", "evidence": [ { "id": "XP_003501953", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501953" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613865.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003501953", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501953" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IET3", "url": "https://www.uniprot.org/uniprotkb/A0A061IET3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Podnl1", "url": "https://www.uniprot.org/uniprotkb/A0A061IET3", "locus": {} } ], "crossref": [ { "id": "100759324", "url": "https://www.ncbi.nlm.nih.gov/gene/100759324", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759324", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759324", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061IET3", "url": "https://www.orthodb.org/?gene=A0A061IET3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45712", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45712:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003501953", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501953", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IET3", "url": "https://www.uniprot.org/uniprotkb/A0A061IET3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IET3-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IET3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGSCSHRGCWSKRMLHRNLRGTTGLIMRPQELLLLLMLRWTEAHMEDLAFPHLGDSSQPLSRACPWRCSCPRDDTVDCAGLGLRVFPDNITRAARHLSLQNNQLQELPYNELSRLSGLCTLDLHSNLISSEGLPDEAFESLTQLEHFYVAHNKLSVAPQFLPRTLRVADLAANEVVEIFPLTFGEKPALRSVYLHNNRLNNTGLPPNTFHGSEAITTLSLSSNQLSYLPPSLPASLERLHLQNNLISKVPRGALSLQTQLRELYLQHNQLTDGGLDATTFSKLSSLEYLDLSHNQLATVPEGLPRTLTILHLGRNCIRQVEAGRLHRARGLRYLLLPHNELGASALPAGTLRPLRALHTLHLYGNRLERVPPALPRHLKALVMPHNRVAVLGARDLVSARTLVELNLAYNRLASAHVHPGAFRRLRVLRSLDLAGNQLSRLPEGLPASLRSLRLQRNQLRGLEPELLAGLNRLQELSLAHNRLRVGDIGPGTWHELQALQVLDLSHNELSFVPPDLPEALEELYLQANRISHVGPEAFLSTPRLRALFLRANRLHMTSIPAETFLGLAHLRVVDTAENPEQVLVQLPPKDRGP", "length": 594, "header": "tr|A0A061IET3-1|A0A061IET3_CRIGR Isoform 1 of Podocan-like protein 1 OS=Cricetulus griseus OX=10029 GN=Podnl1 PE=4 SV=1 CANONICAL=A0A061IET3-1" }, "isoforms": [ { "isoform_ac": "A0A061IET3-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IET3/entry#A0A061IET3-1", "sequence": { "sequence": "MEGSCSHRGCWSKRMLHRNLRGTTGLIMRPQELLLLLMLRWTEAHMEDLAFPHLGDSSQPLSRACPWRCSCPRDDTVDCAGLGLRVFPDNITRAARHLSLQNNQLQELPYNELSRLSGLCTLDLHSNLISSEGLPDEAFESLTQLEHFYVAHNKLSVAPQFLPRTLRVADLAANEVVEIFPLTFGEKPALRSVYLHNNRLNNTGLPPNTFHGSEAITTLSLSSNQLSYLPPSLPASLERLHLQNNLISKVPRGALSLQTQLRELYLQHNQLTDGGLDATTFSKLSSLEYLDLSHNQLATVPEGLPRTLTILHLGRNCIRQVEAGRLHRARGLRYLLLPHNELGASALPAGTLRPLRALHTLHLYGNRLERVPPALPRHLKALVMPHNRVAVLGARDLVSARTLVELNLAYNRLASAHVHPGAFRRLRVLRSLDLAGNQLSRLPEGLPASLRSLRLQRNQLRGLEPELLAGLNRLQELSLAHNRLRVGDIGPGTWHELQALQVLDLSHNELSFVPPDLPEALEELYLQANRISHVGPEAFLSTPRLRALFLRANRLHMTSIPAETFLGLAHLRVVDTAENPEQVLVQLPPKDRGP", "length": 594, "header": "tr|A0A061IET3-1|A0A061IET3_CRIGR Isoform 1 of Podocan-like protein 1 OS=Cricetulus griseus OX=10029 GN=Podnl1 PE=4 SV=1 CANONICAL=A0A061IET3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IET3", "url": "https://www.uniprot.org/uniprotkb/A0A061IET3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IET3", "url": "https://www.uniprot.org/uniprotkb/A0A061IET3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759324", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759324", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A061IET3", "url": "https://www.uniprot.org/uniprotkb/A0A061IET3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 90, "end_pos": 92, 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}, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061IEW9-1", "uniprot_ac": "A0A061IEW9", "uniprot_id": "A0A061IEW9_CRIGR", "mass": { "chemical_mass": 37357.0, "monoisotopic_mass": 37357.0 }, "refseq": { "ac": "XP_027266314", "name": "Fanconi anemia group F protein isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266314" }, "gene_names": [ { "name": "Fancf", "type": "recommended", "evidence": [ { "id": "A0A061IEW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IEW9" } ] }, { "name": "Fancf", "type": "synonym", "evidence": [ { "id": "XP_027266314", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266314" } ] } ], "protein_names": [ { "name": "Fanconi anemia group F protein", "type": "recommended", "evidence": [ { "id": "A0A061IEW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IEW9/entry#names_and_taxonomy" } ] }, { "name": "Fanconi anemia group F protein isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027266314", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266314" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027266314", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266314" } ] }, { "annotation": "DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.", "evidence": [ { "database": "UniProtKB", "id": "A0A061IEW9", "url": "https://www.uniprot.org/uniprotkb/A0A061IEW9#function" }, { "database": "UniProtKB", "id": "ARBA00059878", "url": "https://www.uniprot.org/uniprotkb/ARBA00059878#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IEW9", "url": "https://www.uniprot.org/uniprotkb/A0A061IEW9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Fancf", "url": "https://www.uniprot.org/uniprotkb/A0A061IEW9", "locus": {} } ], "crossref": [ { "id": "103161842", "url": "https://www.ncbi.nlm.nih.gov/gene/103161842", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR035428", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035428", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038505", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038505", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:103161842", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103161842", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061IEW9", "url": "https://www.orthodb.org/?gene=A0A061IEW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14449", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14449", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14449:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14449:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11107", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11107", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027266314", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266314", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IEW9", "url": "https://www.uniprot.org/uniprotkb/A0A061IEW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IEW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IEW9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPLVQHMECFSEVLAVSCGAQVRSWDATTVRRALQWARYLLHVYRRFGGRGRAREALERRLQSRSGPLGLRSFAALEFGDARLALRLLRNRALAPVAAHALPSLLFPGPAADSEDDAPQSRLVLLARRGSALHLLLRLGGDAPRVALLRTHAELLCARLHELGGADPTAAHKLLDTLWTRGPHEHVLSVLGEALLRGLDLELAGAADCVGAKETPKLLQWLLESPEVLVAFCRQLPALRLASLAGCHPALSRAYLDLLTAWATQLHYDLQKGFWSPTQPEDMPWEELCLRLHSLCQASPLLQEEVLERLRGRRALDGDFEVPGMSIWTDLLLALPGGA", "length": 339, "header": "tr|A0A061IEW9-1|A0A061IEW9_CRIGR Isoform 1 of Fanconi anemia group F protein OS=Cricetulus griseus OX=10029 GN=Fancf PE=4 SV=1 CANONICAL=A0A061IEW9-1" }, "isoforms": [ { "isoform_ac": "A0A061IEW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IEW9/entry#A0A061IEW9-1", "sequence": { "sequence": "MEPLVQHMECFSEVLAVSCGAQVRSWDATTVRRALQWARYLLHVYRRFGGRGRAREALERRLQSRSGPLGLRSFAALEFGDARLALRLLRNRALAPVAAHALPSLLFPGPAADSEDDAPQSRLVLLARRGSALHLLLRLGGDAPRVALLRTHAELLCARLHELGGADPTAAHKLLDTLWTRGPHEHVLSVLGEALLRGLDLELAGAADCVGAKETPKLLQWLLESPEVLVAFCRQLPALRLASLAGCHPALSRAYLDLLTAWATQLHYDLQKGFWSPTQPEDMPWEELCLRLHSLCQASPLLQEEVLERLRGRRALDGDFEVPGMSIWTDLLLALPGGA", "length": 339, "header": "tr|A0A061IEW9-1|A0A061IEW9_CRIGR Isoform 1 of Fanconi anemia group F protein OS=Cricetulus griseus OX=10029 GN=Fancf PE=4 SV=1 CANONICAL=A0A061IEW9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 169, "start_aa": "Thr", "end_pos": 169, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr169", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IEW9", "url": "https://www.uniprot.org/uniprotkb/A0A061IEW9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IEW9", "url": "https://www.uniprot.org/uniprotkb/A0A061IEW9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:103161842", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103161842", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Fanconi anaemia nuclear complex", "id": "GO:0043240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043240", "evidence": [ { "database": "UniProtKB", "id": "A0A061IEW9", "url": "https://www.uniprot.org/uniprotkb/A0A061IEW9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "interstrand cross-link repair", "id": "GO:0036297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036297", "evidence": [ { "database": "UniProtKB", "id": "A0A061IEW9", "url": "https://www.uniprot.org/uniprotkb/A0A061IEW9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 169 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061IF00-1", "uniprot_ac": "A0A061IF00", "uniprot_id": "A0A061IF00_CRIGR", "mass": { "chemical_mass": 72823.0, "monoisotopic_mass": 72823.0 }, "refseq": { "ac": "XP_007651749", "name": "ubiquilin-3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651749" }, "gene_names": [ { "name": "Ubqln3", "type": "recommended", "evidence": [ { "id": "A0A061IF00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IF00" } ] }, { "name": "Ubqln3", "type": "synonym", "evidence": [ { "id": "XP_007651749", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651749" } ] } ], "protein_names": [ { "name": "Ubiquilin-3", "type": "recommended", "evidence": [ { "id": "A0A061IF00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IF00/entry#names_and_taxonomy" } ] }, { "name": "ubiquilin-3", "type": "synonym", "evidence": [ { "id": "XP_007651749", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651749" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615815.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007651749.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007651749", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651749" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IF00", "url": "https://www.uniprot.org/uniprotkb/A0A061IF00" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ubqln3", "url": "https://www.uniprot.org/uniprotkb/A0A061IF00", "locus": {} } ], "crossref": [ { "id": "cd01808", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01808", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14399", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14399", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100763544", "url": "https://www.ncbi.nlm.nih.gov/gene/100763544", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006636", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763544", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763544", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061IF00", "url": "https://www.orthodb.org/?gene=A0A061IF00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10677", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10677", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10677:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10677:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00627", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00627", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23195", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23195", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007651749", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651749", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IF00", "url": "https://www.uniprot.org/uniprotkb/A0A061IF00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IF00-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IF00-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MISVFHPYPFSCVPTDLGFLLPTMAKSGEALPQGSPAPAQDSHLIRVTVKTPKDKEDFSVVDTCTIRQLKEEISHRFKAHPNQLVLIFAGKILKDPDSLAQCGVRDGLTVHLVIKMQRRTTGTECPAPPVSTSGPNPGVLPQSSSVYPVDGSPSFSLGVLTGLSGLGLTSGSFSDQPGSLMWQHISVPELVAQLVDDPFIQGLLSNTGLVRQLVLDNPHMQQLIQQNPEIGHILNNPEIMRQTMEFLRNPSMMQEMMRSQDRALSNLESIPGGYNVLRTMYTDIMDPMLNAVQEQFGGNPFATTATASTTTSSSQPSRTENCDPLPNPWTSTYGVSGSRQGRQSGDQDASESRNRLPSFLGNIGLFDYLQQLHETSQSLGSYLQGTVPTQSSSQEAPLSENRVPPTLPSSQKPGSGQPLPKESVAVKGKSSCPTFLRHSSENSTGQGGNLHDAGKGSTGQSTSLPNLTSQIGDSANRSPFVPTLSSLVAATAGDPETPWLPPTGYPRPLRSAGTNQVPRIQNEIHQQLPLLLHLQAAMANPRVMQALVQIEQGLQILATEAPRLLLWFMPCLTGLSGVTGGTESRDGAVTSEDPHPAPAPQVSHTQGSAELGFHSTPFLQVLQALASTNPQQLQLEAHFRVQLEQLRAMGFLNLEANLQALIATGGDVDAAVEKLRKP", "length": 678, "header": "tr|A0A061IF00-1|A0A061IF00_CRIGR Isoform 1 of Ubiquilin-3 OS=Cricetulus griseus OX=10029 GN=Ubqln3 PE=4 SV=1 CANONICAL=A0A061IF00-1" }, "isoforms": [ { "isoform_ac": "A0A061IF00-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IF00/entry#A0A061IF00-1", "sequence": { "sequence": "MISVFHPYPFSCVPTDLGFLLPTMAKSGEALPQGSPAPAQDSHLIRVTVKTPKDKEDFSVVDTCTIRQLKEEISHRFKAHPNQLVLIFAGKILKDPDSLAQCGVRDGLTVHLVIKMQRRTTGTECPAPPVSTSGPNPGVLPQSSSVYPVDGSPSFSLGVLTGLSGLGLTSGSFSDQPGSLMWQHISVPELVAQLVDDPFIQGLLSNTGLVRQLVLDNPHMQQLIQQNPEIGHILNNPEIMRQTMEFLRNPSMMQEMMRSQDRALSNLESIPGGYNVLRTMYTDIMDPMLNAVQEQFGGNPFATTATASTTTSSSQPSRTENCDPLPNPWTSTYGVSGSRQGRQSGDQDASESRNRLPSFLGNIGLFDYLQQLHETSQSLGSYLQGTVPTQSSSQEAPLSENRVPPTLPSSQKPGSGQPLPKESVAVKGKSSCPTFLRHSSENSTGQGGNLHDAGKGSTGQSTSLPNLTSQIGDSANRSPFVPTLSSLVAATAGDPETPWLPPTGYPRPLRSAGTNQVPRIQNEIHQQLPLLLHLQAAMANPRVMQALVQIEQGLQILATEAPRLLLWFMPCLTGLSGVTGGTESRDGAVTSEDPHPAPAPQVSHTQGSAELGFHSTPFLQVLQALASTNPQQLQLEAHFRVQLEQLRAMGFLNLEANLQALIATGGDVDAAVEKLRKP", "length": 678, "header": "tr|A0A061IF00-1|A0A061IF00_CRIGR Isoform 1 of Ubiquilin-3 OS=Cricetulus griseus OX=10029 GN=Ubqln3 PE=4 SV=1 CANONICAL=A0A061IF00-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IF00", "url": "https://www.uniprot.org/uniprotkb/A0A061IF00" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IF00", "url": "https://www.uniprot.org/uniprotkb/A0A061IF00" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763544", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763544", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A061IF00", "url": "https://www.uniprot.org/uniprotkb/A0A061IF00" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "polyubiquitin modification-dependent protein binding", "id": "GO:0031593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031593", "evidence": [ { "database": "UniProtKB", "id": "A0A061IF00", "url": "https://www.uniprot.org/uniprotkb/A0A061IF00" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A061IF00", "url": "https://www.uniprot.org/uniprotkb/A0A061IF00" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 442, "end_pos": 444, "annotation": "n_glycosylation_sequon" }, { "start_pos": 466, "end_pos": 468, "annotation": "n_glycosylation_sequon" }, { "start_pos": 476, "end_pos": 478, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061IF00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IF00" }, { "id": "PS50030", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50030" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBA", "eco_id": "ECO_0000259", "start_pos": 634, "end_pos": 678, "start_aa": "Gln", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A061IF00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IF00" }, { "id": "PS50053", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50053" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquitin-like", "eco_id": "ECO_0000259", "start_pos": 45, "end_pos": 119, "start_aa": "Ile", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 442, "end_pos": 444 }, { "start_pos": 466, "end_pos": 468 }, { "start_pos": 476, "end_pos": 478 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061IF21-1", "uniprot_ac": "A0A061IF21", "uniprot_id": "A0A061IF21_CRIGR", "mass": { "chemical_mass": 40822.0, "monoisotopic_mass": 40822.0 }, "refseq": { "ac": "XP_003514203", "name": "WD repeat-containing protein 73 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514203" }, "gene_names": [ { "name": "Wdr73", "type": "recommended", "evidence": [ { "id": "A0A061IF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IF21" } ] }, { "name": "Wdr73", "type": "synonym", "evidence": [ { "id": "XP_003514203", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514203" } ] } ], "protein_names": [ { "name": "WD repeat-containing protein 73 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003514203", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514203" }, { "id": "A0A061IF21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IF21/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616388.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003514203", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514203" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IF21", "url": "https://www.uniprot.org/uniprotkb/A0A061IF21" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Wdr73", "url": "https://www.uniprot.org/uniprotkb/A0A061IF21", "locus": {} } ], "crossref": [ { "id": "100771456", "url": "https://www.ncbi.nlm.nih.gov/gene/100771456", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042795", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042795", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771456", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771456", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CKPRTLL", "url": "https://omabrowser.org/oma/group/CKPRTLL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061IF21", "url": "https://www.orthodb.org/?gene=A0A061IF21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46947", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46947", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46947:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46947:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_003514203", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514203", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IF21", "url": "https://www.uniprot.org/uniprotkb/A0A061IF21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IF21-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IF21-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GWJ4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GWJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GWJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GWJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELAEDWLVESLRLYQDFHAFDLSGATRVLEWIGEKGVFVAGYESSKKNEILHLILPLRLSVKENQGLFPERDFKVRHGGFSDRSVFDLKHVPDTRLLVTTGLPGCYLQVWQIGEDNDVIEAVSTIDVQDREKSLWPRVSVFSTAAPGILHGTRLSGLKTVDIESQKITYSSGTSDSESLSSLQVLDSDTFAFCGTSGRLGLVDTRQKWAPLEAFSPSPDSSGQRWCADVRNRGQGPGPCVASLGSDGQLCLLDPRNLCHPVSSAQCPVSKSSPDPELLRVSWAPGLDNCLAISGFDGTVQIYDVTSWDGKKSQVESLFTHKGHILLDGNEIDATPLVTTHTWHPCKPRTLLSAASDASLHVWDWVDLQASC", "length": 372, "header": "tr|A0A061IF21-1|A0A061IF21_CRIGR Isoform 1 of WD repeat-containing protein 73 isoform X1 OS=Cricetulus griseus OX=10029 GN=Wdr73 PE=4 SV=1 CANONICAL=A0A061IF21-1" }, "isoforms": [ { "isoform_ac": "A0A061IF21-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IF21/entry#A0A061IF21-1", "sequence": { "sequence": "MELAEDWLVESLRLYQDFHAFDLSGATRVLEWIGEKGVFVAGYESSKKNEILHLILPLRLSVKENQGLFPERDFKVRHGGFSDRSVFDLKHVPDTRLLVTTGLPGCYLQVWQIGEDNDVIEAVSTIDVQDREKSLWPRVSVFSTAAPGILHGTRLSGLKTVDIESQKITYSSGTSDSESLSSLQVLDSDTFAFCGTSGRLGLVDTRQKWAPLEAFSPSPDSSGQRWCADVRNRGQGPGPCVASLGSDGQLCLLDPRNLCHPVSSAQCPVSKSSPDPELLRVSWAPGLDNCLAISGFDGTVQIYDVTSWDGKKSQVESLFTHKGHILLDGNEIDATPLVTTHTWHPCKPRTLLSAASDASLHVWDWVDLQASC", "length": 372, "header": "tr|A0A061IF21-1|A0A061IF21_CRIGR Isoform 1 of WD repeat-containing protein 73 isoform X1 OS=Cricetulus griseus OX=10029 GN=Wdr73 PE=4 SV=1 CANONICAL=A0A061IF21-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GWJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IF21/entry#A0A9J7GWJ4-1", "sequence": { "sequence": "MELAEDWLVESLRLYQDFHAFDLSGATRVLEWIGEKGVFVAGYESSKKNEILHLILPLRLSVKENQGLFPERDFKVRHGGFSDRSVFDLKHVPDTRLLVTTGLPGCYLQVWQIGEDNDVIEAVSTIDVQDREKSLWPRVSVFSTAAPGILHGTRLSGLKTVDIESQKITYSSGRLGLVDTRQKWAPLEAFSPSPDSSGQRWCADVRNRGQGPGPCVASLGSDGQLCLLDPRNLCHPVSSAQCPVSKSSPDPELLRVSWAPGLDNCLAISGFDGTVQIYDVTSWDGKKSQVESLFTHKGHILLDGNEIDATPLVTTHTWHPCKPRTLLSAASDASLHVWDWVDLQASC", "length": 347, "header": "tr|A0A9J7GWJ4-1|A0A9J7GWJ4_CRIGR Computationally mapped isoform of WD repeat-containing protein 73 isoform X2 OS=Cricetulus griseus OX=10029 GN=Wdr73 PE=4 SV=1 CANONICAL=A0A061IF21-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IF21", "url": "https://www.uniprot.org/uniprotkb/A0A061IF21" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IF21", "url": "https://www.uniprot.org/uniprotkb/A0A061IF21" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771456", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771456", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480K409-1", "protein_name": "WD repeat domain 73", "gene_name": "WDR73", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPAEDWLVESLRLYQDFHEFDLSGATRVLEWIGDKGILVAGYESLKKNEILHLILPLRLSVKENQGLFPERDFKVRHGGFSDRSVFDLKHVPDTRLLVTSGLPGCYLQVWQVAEDSDVIKAVSTIDAHEKEGHPWPRLAIFSSPAPGVLHGARLSSLKVVDLESHKSTYTSGISEDELLSSLQVLDANTFAFCCTSGRLGLVDTRQKWAPSENLRPSPGSAGGRWYAEVGGRGPGPRIASLGSDGQLCLLDLRDLSQPVSSVQCPVSTPSPDPELLRVTWAPGLDNCLAISGFDGTVQVYDVTSWNGVGGQVEPLFTHRGHIFLDDSGVDTAPLVTTHTWHPCKPRTLLSAASDASLHVWDWVDLRASH", "length": 370 }, "evidence": [ { "id": "A0A061IF21", "url": "https://omabrowser.org/oma/group/A0A061IF21/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0X3H4-1", "protein_name": "WD repeat domain 73", "gene_name": "WDR73", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEAAGERGEEEEEEEEEEEWLLQSLHLYEALHAFELQAPTRVIEWALGKRVCVAGYGCAGRNEILQLLPPAALEAKESRGLCPERDFKVECGGFSNRPVYNLKHVPDTSLLVTSGPPDSSLQLWQMSAEDSDVIKSVSAISTENSTGEGWAKIATISMRAPWVLHGSRLSSTQITEVESRKKVYVAASSSGEEQLSSLAFVDANTSLLCCTAGQLCVADIRQHSPLQAAPIPSAQRGQCWCMAVGRRALCSELSSQPIACLSSAGQLVLMDVRKASQCLASAKCRVPSSSCSAEFLSVSWAPALEGCLAVSAIPQSLSCTKKHVSAAWPCSLFPTSCPGHSASARIPREHPRAPGKVSTEGCNEETFGAAASIWGGFPLQINVWGRGATRRAGEQSNANAAPIKWSLGRKGGWGGGVKRSIGTLWVRLCVCVFVSEVNKLE", "length": 441 }, "evidence": [ { "id": "A0A061IF21", "url": "https://omabrowser.org/oma/group/A0A061IF21/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AAA9TA72-1", "protein_name": "WD repeat domain 73", "gene_name": "WDR73", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDCSRPAPLSMGLSRYQDFHAFDLSGATRVLEWIGDKGILVAGYDSLKKNEILHLILPLRLSVKENQGLFPERDFKVQHGGFSDRSVCDLKHVPDTRLLVTSGPPGSYLQVWQLAEDSDVIRAVSTIDVHEREEPLWPRVAIFPSVAPGVLHGTRLSSLKVVDLHSQKTMYTSGVSDDDVLSSLQVLDTDTFAFCCSSGRLGLVDTRQRWAPSENLSPGPGSTGRQWCAEAGGRGPGPSIARLGSDGQLCLLDPRDLCQPVSSVQCPVSMPSPEPELLRVTWAPGLDNCLAISGFDGTVQVYDVTSWAGVGRQVEPLFTHRGHIFLDDSGMDPAPLVTTHTWHPYKPRTVLSAASDASLHVWDWVDPCASR", "length": 371 }, "evidence": [ { "id": "A0A061IF21", "url": "https://omabrowser.org/oma/group/A0A061IF21/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0LB16-1", "protein_name": "WD repeat domain 73", "gene_name": "Wdr73", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "YTSPATKRGGFLPRAEPLERPIQLPCPDTRLLREWGSYCFVSSGVFVAGYESLKKNEILHLILPLRLSVKENQGLYPERDFKVRHGGFSDRAVFDLKHVPDTRLLVTSGLPGCYIQVWQIREDNDVIEAVSTIDVQDKEESLWPRVSIFCSAAPGILHGARLSGLRTVDVESRKITYSSDTTDSESLSSLQVLDADTFAFCGTSGRLGLVDTRQKWAPLETVSPRAGSSGERWCAEVRSKGQGPGPCIASLGSDGQLCLLDPRNLRDPVSSAQCPVFKSSPDPELLRVTWAPGLDNCLAISGFDGTVQIYDVTSWDGKKTQVEALFIHKGHIFLDGNEVESAPLVTTHTWHPSKPRTLLSAASDAALHVWDWVDLQAS", "length": 378 }, "evidence": [ { "id": "A0A061IF21", "url": "https://omabrowser.org/oma/group/A0A061IF21/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6P4I2-1", "protein_name": "Integrator complex assembly factor WDR73", "gene_name": "WDR73", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPGDDWLVESLRLYQDFYAFDLSGATRVLEWIDDKGVFVAGYESLKKNEILHLKLPLRLSVKENKGLFPERDFKVRHGGFSDRSIFDLKHVPHTRLLVTSGLPGCYLQVWQVAEDSDVIKAVSTIAVHEKEESLWPRVAVFSTLAPGVLHGARLRSLQVVDLESRKTTYTSDVSDSEELSSLQVLDADTFAFCCASGRLGLVDTRQKWAPLENRSPGPGSGGERWCAEVGSWGQGPGPSIASLGSDGRLCLLDPRDLCHPVSSVQCPVSVPSPDPELLRVTWAPGLKNCLAISGFDGTVQVYDATSWDGTRSQDGTRSQVEPLFTHRGHIFLDGNGMDPAPLVTTHTWHPCRPRTLLSATNDASLHVWDWVDLCAPR", "length": 378 }, "evidence": [ { "id": "A0A061IF21", "url": "https://omabrowser.org/oma/group/A0A061IF21/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CWR1-1", "protein_name": "Integrator complex assembly factor WDR73", "gene_name": "Wdr73", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELAEDWLVESLRLYQDFHAFDLSGATRVLEWIGEKGVFVAGYESLKKNEILHLILPLRLSVQENQGLHPERDFKVRHGGFSDRSVFDLKHVPDTRLLVTSGLPGCYIQMWQVREDNDVIEAVSTIDVQDKEESLWPRVSVFCSKAPGILHGARLSGLRTVDVESQKITYSSGTADSESLSCLQVLDANTFAFCGNSGRLGLVDTRQKWAALETVSPGSGCSGERWCAEVRNKGQGPGPCIASLGSDGQLCLLDSRNLCHPVSSAQCPVFKPSPDPELLRVTWAPGLDNCLAISGFDGTVQIYDVTSWDGKKTQAEPLFTHKGHIFLDGNDVDSAPLVTTHTWHPRKPRTLLSAASDSSLHVWDWVDLQAS", "length": 371 }, "evidence": [ { "id": "A0A061IF21", "url": "https://omabrowser.org/oma/group/A0A061IF21/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "spindle pole", "id": "GO:0000922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000922", "evidence": [ { "database": "UniProtKB", "id": "A0A061IF21", "url": "https://www.uniprot.org/uniprotkb/A0A061IF21" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A061IF21", "url": "https://www.uniprot.org/uniprotkb/A0A061IF21" } ], "pmid": "" }, { "name": "cleavage furrow", "id": "GO:0032154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032154", "evidence": [ { "database": "UniProtKB", "id": "A0A061IF21", "url": "https://www.uniprot.org/uniprotkb/A0A061IF21" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A061IF21", "url": "https://www.uniprot.org/uniprotkb/A0A061IF21" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "nucleus organization", "id": "GO:0006997", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006997", "evidence": [ { "database": "UniProtKB", "id": "A0A061IF21", "url": "https://www.uniprot.org/uniprotkb/A0A061IF21" } ], "pmid": "" }, { "name": "cytoplasmic microtubule organization", "id": "GO:0031122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031122", "evidence": [ { "database": "UniProtKB", "id": "A0A061IF21", "url": "https://www.uniprot.org/uniprotkb/A0A061IF21" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061IIP3-1", "uniprot_ac": "A0A061IIP3", "uniprot_id": "A0A061IIP3_CRIGR", "mass": { "chemical_mass": 46597.0, "monoisotopic_mass": 46597.0 }, "refseq": { "ac": "XP_027257350", "name": "trafficking protein particle complex subunit 13 isoform X7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257350" }, "gene_names": [ { "name": "Trappc13", "type": "recommended", "evidence": [ { "id": "A0A061IIP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IIP3" } ] }, { "name": "Trappc13", "type": "synonym", "evidence": [ { "id": "XP_027257350", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257350" } ] } ], "protein_names": [ { "name": "Trafficking protein particle complex subunit 13", "type": "recommended", "evidence": [ { "id": "A0A061IIP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IIP3/entry#names_and_taxonomy" } ] }, { "name": "trafficking protein particle complex subunit 13 isoform X7", "type": "synonym", "evidence": [ { "id": "XP_027257350", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257350" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027257350", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257350" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IIP3", "url": "https://www.uniprot.org/uniprotkb/A0A061IIP3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Trappc13", "url": "https://www.uniprot.org/uniprotkb/A0A061IIP3", "locus": {} } ], "crossref": [ { "id": "cd22293", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22293", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100761869", "url": "https://www.ncbi.nlm.nih.gov/gene/100761869", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010378", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010378", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039996", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039996", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055428", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055428", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055429", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055429", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761869", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761869", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061IIP3", "url": "https://www.orthodb.org/?gene=A0A061IIP3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A061IJQ5", "url": "https://www.orthodb.org/?gene=A0A061IJQ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FH12", "url": "https://www.orthodb.org/?gene=A0A9J7FH12", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13134", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13134", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13134:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13134:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR41404", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR41404", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR41404:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR41404:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06159", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06159", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23647", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23647", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027257350", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257350", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IF38", "url": "https://www.uniprot.org/uniprotkb/A0A061IF38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IF38-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IF38-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IIP3", "url": "https://www.uniprot.org/uniprotkb/A0A061IIP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IIP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IIP3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IJQ5", "url": "https://www.uniprot.org/uniprotkb/A0A061IJQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IJQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IJQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FF63", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FF63-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FF63-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FH12", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FH12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FH12-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FH12-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JV60", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JV60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JV60-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JV60-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K584", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K584", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K584-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K584-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVNPPKQEHLLALKVMRLTKPTLFTNIPVTCEEKDLPGDLFNQLMRDDPSTVNGAEILMLGEMLTLPQNFGNIFLGETFSSYISVHNDSNQVVKDILVKADLQTSSQRLNLSASNAAVAELKPDCCIDDVIHHEVKEIGTHILVCAVSYTTQGGEKMYFRKFFKFQVLKPLDVKTKFYNAESDLSSVTDEVFLEAQIQNITTSPMFMEKVSLEPSIMYNVTELNSVTQAGECVSTFGSRGYLQPMDTRQYLYCLKPKKEFAEKAGIIKGVTVIGKLDIVWKTNLGERGRLQTSQLQRMAPGYGDVRLSLEAIPDTVNLEEPFRITCKITNCSSERTMDLVLEMCNTNSIHWCGISGRQLGKLHPSSSLCLALTLLSSVQGLQSISGLRLTDTFLKRTYEYDDIAQVCVVSSAVEVEA", "length": 418, "header": "tr|A0A061IIP3-1|A0A061IIP3_CRIGR Isoform 1 of Trafficking protein particle complex subunit 13 OS=Cricetulus griseus OX=10029 GN=Trappc13 PE=3 SV=1 CANONICAL=A0A061IIP3-1" }, "isoforms": [ { "isoform_ac": "A0A061IF38-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IIP3/entry#A0A061IF38-1", "sequence": { "sequence": "MEVNPPKQEHLLALKVMRLTKPTLFTNIPVTCEEKDLPGDLFNQLMRDDPSTVNGAEILMLGEMLTLPQNFGNIFLGETFSSYISVHNDSNQVVKDILVKADLQTSSQRLNLSASNAAVAELKPDCCIDDVIHHEVKEIGTHILVCAVSYTTQGGEKMYFRKFFKFQVLKPLDVKTKFYNAETDEVFLEAQIQNITTSPMFMEKVSLEPSIMYNVTELNSVTQAGECVSTFGSRGYLQPMDTRQYLYCLKPKKEFAEKAGIIKGVTVIGKLDIVWKTNLGERGRLQTSQLQRMAPGYGDVRLSLEAIPDTVNLEEPFRITCKITNCSSERTMDLVLEMCNTNSIHWCGISGRQLGKLHPSSSLCLALTLLSSVQGLQSISGLRLTDTFLKRTYEYDDIAQVCVVSSAVEVEA", "length": 412, "header": "tr|A0A061IF38-1|A0A061IIP3_CRIGR Computationally mapped isoform of Trafficking protein particle complex subunit 13 OS=Cricetulus griseus OX=10029 GN=Trappc13 PE=3 SV=1 CANONICAL=A0A061IIP3-1" }, "locus": {} }, { "isoform_ac": "A0A061IIP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IIP3/entry#A0A061IIP3-1", "sequence": { "sequence": "MEVNPPKQEHLLALKVMRLTKPTLFTNIPVTCEEKDLPGDLFNQLMRDDPSTVNGAEILMLGEMLTLPQNFGNIFLGETFSSYISVHNDSNQVVKDILVKADLQTSSQRLNLSASNAAVAELKPDCCIDDVIHHEVKEIGTHILVCAVSYTTQGGEKMYFRKFFKFQVLKPLDVKTKFYNAESDLSSVTDEVFLEAQIQNITTSPMFMEKVSLEPSIMYNVTELNSVTQAGECVSTFGSRGYLQPMDTRQYLYCLKPKKEFAEKAGIIKGVTVIGKLDIVWKTNLGERGRLQTSQLQRMAPGYGDVRLSLEAIPDTVNLEEPFRITCKITNCSSERTMDLVLEMCNTNSIHWCGISGRQLGKLHPSSSLCLALTLLSSVQGLQSISGLRLTDTFLKRTYEYDDIAQVCVVSSAVEVEA", "length": 418, "header": "tr|A0A061IIP3-1|A0A061IIP3_CRIGR Isoform 1 of Trafficking protein particle complex subunit 13 OS=Cricetulus griseus OX=10029 GN=Trappc13 PE=3 SV=1 CANONICAL=A0A061IIP3-1" }, "locus": {} }, { "isoform_ac": "A0A061IJQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IIP3/entry#A0A061IJQ5-1", "sequence": { "sequence": "MEVNPPKQEHLLALKVMRLTKPTLFTNIPVTCEEKDLPGDLFNQLMRDDPSTVNGAEILMLGEMLTLPQNFGNIFLGETFSSYISVHNDSNQVVKDILVKADLQTSSQRLNLSASNAAVAELKPDCCIDDVIHHEVKEIGTHILVCAVSYTTQGGEKMYFRKFFKFQVLKPLDVKTKFYNAESDLSSVTDEVFLEAQIQNITTSPMFMEKVSLEPSIMYNVTELNSVTQAGECVSTFGSRGYLQPMDTRQYLYCLKPKKEFAEKAGIIKGVTVIGKLDIVWKTNLGERGRLQTSQLQRMAPGYGDVRLSLEAIPDTVNLEEPFRITCKITNCSERTMDLVLEMCNTNSIHWCGISGRQLGKLHPSSSLCLALTLLSSVQGLQSISGLRLTDTFLKRTYEYDDIAQVCVVSSAVEVEA", "length": 417, "header": "tr|A0A061IJQ5-1|A0A061IJQ5_CRIGR Computationally mapped isoform of Trafficking protein particle complex subunit 13 OS=Cricetulus griseus OX=10029 GN=Trappc13 PE=3 SV=1 CANONICAL=A0A061IIP3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FF63-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IIP3/entry#A0A9J7FF63-1", "sequence": { "sequence": "MRDDPSTVNGAEILMLGEMLTLPQNFGNIFLGETFSSYISVHNDSNQVVKDILVKADLQTSSQRLNLSASNAAVAELKPDCCIDDVIHHEVKEIGTHILVCAVSYTTQGGEKMYFRKFFKFQVLKPLDVKTKFYNAESDLSSVTDEVFLEAQIQNITTSPMFMEKVSLEPSIMYNVTELNSVTQAGECVSTFGSRGYLQPMDTRQYLYCLKPKKEFAEKAGIIKGVTVIGKLDIVWKTNLGERGRLQTSQLQRMAPGYGDVRLSLEAIPDTVNLEEPFRITCKITNCSSERTMDLVLEMCNTNSIHWCGISGRQLGKLHPSSSLCLALTLLSSVQGLQSISGLRLTDTFLKRTYEYDDIAQVCVVSSAVEVEA", "length": 373, "header": "tr|A0A9J7FF63-1|A0A9J7FF63_CRIGR Computationally mapped isoform of Trafficking protein particle complex subunit 13 OS=Cricetulus griseus OX=10029 GN=Trappc13 PE=3 SV=1 CANONICAL=A0A061IIP3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FH12-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IIP3/entry#A0A9J7FH12-1", "sequence": { "sequence": "MEVNPPKQEHLLALKVMRLTKPTLFTNIPVTCEEKDLPGDLFNQLMRDDPSTVNGAEILMLGEMLTLPQNFGNIFLGETFSSYISVHNDSNQVVKDILVKADLQTSSQRLNLSASNAAVAELKPDCCIDDVIHHEVKEIGTHILVCAVSYTTQGGEKMYFRKFFKFQVLKPLDVKTKFYNAETDEVFLEAQIQNITTSPMFMEKVSLEPSIMYNVTELNSVTQAGECVSTFGSRGYLQPMDTRQYLYCLKPKKEFAEKAGIIKGVTVIGKLDIVWKTNLGERGRLQTSQLQRMAPGYGDVRLSLEAIPDTVNLEEPFRITCKITNCSERTMDLVLEMCNTNSIHWCGISGRQLGKLHPSSSLCLALTLLSSVQGLQSISGLRLTDTFLKRTYEYDDIAQVCVVSSAVEVEA", "length": 411, "header": "tr|A0A9J7FH12-1|A0A9J7FH12_CRIGR Computationally mapped isoform of Trafficking protein particle complex subunit 13 OS=Cricetulus griseus OX=10029 GN=Trappc13 PE=3 SV=1 CANONICAL=A0A061IIP3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JV60-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IIP3/entry#A0A9J7JV60-1", "sequence": { "sequence": "MEVNPPKQEHLLALKEFMDHCRMTTEVILHYRPYEKDPTQLAKIAEKAIQDFPTHQLSRFIPWFPQDGSKLPLKPKRLPPVVSGEAAENVKQYITVSEPSVKSQSYDCTVDLLEFQPSLKTQHLIQSHMLNEQNNPGNVDRNSDKGKLHRKRSWSISLASKHCPKKNFPLSEQLQAILKTLHLHSLHRARWTLEYSACNNQTLEDIWTKLNHLIRHNELPSSNATIQRQLGQIWVFCDIMYCEYVGNLLKERLSLIGKIHLFVRKYGVIFSM", "length": 272, "header": "tr|A0A9J7JV60-1|A0A9J7JV60_CRIGR Computationally mapped isoform of Trafficking protein particle complex subunit 13 isoform X12 OS=Cricetulus griseus OX=10029 GN=Trappc13 PE=4 SV=1 CANONICAL=A0A061IIP3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K584-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IIP3/entry#A0A9J7K584-1", "sequence": { "sequence": "MDHCRMTTEVILHYRPYEKDPTQLAKIAEKAIQDFPTHQLSRFIPWFPQDGSKLPLKPKRLPPVVSGEAAENVKQYITVSEPSVKSQSYDCTVDLLEFQPSLKTQHLIQSHMLNEQNNPGNVDRNSDKGKLHRKRSWSISLASKHCPKKNFPLSEQLQAILKTLHLHSLHRARWTLEYSACNNQTLEDIWTKLNHLIRHNELPSSNATIQRQLGQIWVFCDIMYCEYVGNLLKERLSLIGKIHLFVRKYGVIFSM", "length": 255, "header": "tr|A0A9J7K584-1|A0A9J7K584_CRIGR Computationally mapped isoform of Trafficking protein particle complex subunit 13 isoform X6 OS=Cricetulus griseus OX=10029 GN=Trappc13 PE=4 SV=1 CANONICAL=A0A061IIP3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IF38", "url": "https://www.uniprot.org/uniprotkb/A0A061IF38" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IF38", "url": "https://www.uniprot.org/uniprotkb/A0A061IF38" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761869", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761869", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "TRAPPIII protein complex", "id": "GO:1990072", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990072", "evidence": [ { "database": "UniProtKB", "id": "A0A061IIP3", "url": "https://www.uniprot.org/uniprotkb/A0A061IIP3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of double-strand break repair via homologous recombination", "id": "GO:2000042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000042", "evidence": [ { "database": "UniProtKB", "id": "A0A061IIP3", "url": "https://www.uniprot.org/uniprotkb/A0A061IIP3" } ], "pmid": "" }, { "name": "positive regulation of double-strand break repair via nonhomologous end joining", "id": "GO:2001034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001034", "evidence": [ { "database": "UniProtKB", "id": "A0A061IIP3", "url": "https://www.uniprot.org/uniprotkb/A0A061IIP3" } ], "pmid": "" }, { "name": "positive regulation of isotype switching", "id": "GO:0045830", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045830", "evidence": [ { "database": "UniProtKB", "id": "A0A061IIP3", "url": "https://www.uniprot.org/uniprotkb/A0A061IIP3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061IIP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IIP3" }, { "id": "PF23643", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23643" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Trafficking protein particle complex subunit 13 C-terminal", "eco_id": "ECO_0000259", "start_pos": 314, "end_pos": 409, "start_aa": "Pro", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A061IIP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IIP3" }, { "id": "PF06159", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06159" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Trafficking protein particle complex subunit 13 N-terminal", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 168, "start_aa": "His", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A061IIP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IIP3" }, { "id": "PF23647", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23647" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Trafficking protein particle complex subunit 13 middle", "eco_id": "ECO_0000259", "start_pos": 172, "end_pos": 301, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 111, "end_pos": 113 }, { "start_pos": 200, "end_pos": 202 }, { "start_pos": 220, "end_pos": 222 }, { "start_pos": 331, "end_pos": 333 }, { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061IF83-1", "uniprot_ac": "A0A061IF83", "uniprot_id": "A0A061IF83_CRIGR", "mass": { "chemical_mass": 10423.0, "monoisotopic_mass": 10423.0 }, "refseq": { "ac": "XP_016818982", "name": "tetratricopeptide repeat protein 9C isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016818982" }, "gene_names": [ { "name": "Ttc9c", "type": "recommended", "evidence": [ { "id": "A0A061IF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IF83" } ] }, { "name": "Ttc9c", "type": "synonym", "evidence": [ { "id": "XP_016818982", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016818982" } ] } ], "protein_names": [ { "name": "Tetratricopeptide repeat protein 9C", "type": "recommended", "evidence": [ { "id": "A0A061IF83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IF83/entry#names_and_taxonomy" } ] }, { "name": "tetratricopeptide repeat protein 9C isoform X2", "type": "synonym", "evidence": [ { "id": "XP_016818982", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016818982" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616501.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027265717.1. 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Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027254225", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254225" } ] }, { "annotation": "May be involved in protection from oxidative damage.", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7J805", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J805#function" }, { "database": "UniProtKB", "id": "ARBA00037112", "url": "https://www.uniprot.org/uniprotkb/ARBA00037112#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IFG1", "url": "https://www.uniprot.org/uniprotkb/A0A061IFG1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ncoa7", "url": "https://www.uniprot.org/uniprotkb/A0A061IFG1", "locus": {} } ], "crossref": [ { "id": "cd00118", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00118", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100773831", "url": "https://www.ncbi.nlm.nih.gov/gene/100773831", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036779", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036779", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773831", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773831", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061IFG1", "url": "https://www.orthodb.org/?gene=A0A061IFG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23354", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23354", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23354:SF68", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23354:SF68", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01476", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01476", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07534", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07534", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027254225", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254225", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IFG1", "url": "https://www.uniprot.org/uniprotkb/A0A061IFG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IFG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IFG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IGG3", "url": "https://www.uniprot.org/uniprotkb/A0A061IGG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IGG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IGG3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J805", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J805", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J805-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J805-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDTKEEKKEQKERKQSYFARLKKKKQAKQNAEIISATATRSHSGKEDANSVILEQGKSNLAVEGEYSTDEKKKRKNNQLKEIRRTELKRYYSTDDNQSKTHDKKEKKMVVQKPHGTMEYTAGSQDTLNSIALKFNITPNKLVELNKLFTHTIVPGQVLFVPDANFPSSTLRLSSSTPGATVSPSSSDAEYDKLPDADLARKALKPIERVLSSTSEEDEPGVVKFLKMNCRYFTDGKGVVGGVMIVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYNDISHMKIKDALPSDLPQDLCPLYRPGEWEDLASEKDINPFSKFKSINKEKRQQNGERTLTLDPKPMSSPEESGECTHVKPSDSSESWKLKKLEPSRGTASESPSLTQLSKGPSDTHAALESTAKENCLLGEDDDFVDLEELSSQPGSGMDKGDATKERPSYDQKKSEPQTIMSAKKMQVQSSLDLAGLESEAELKGALDLETCEKQDKVHEIDKQSGSPENQVESTLKIHEDLDKVKLIEFYLNKNKDGSQLSENIQRSELKSSKRMEPGGIDITLSSSLPQTGDSPPEGNKEPGTIWVKEKETLPLKLDPSAEENVINNKEALDALGSSLDKSCQGAQMDNKSEIQLWLLKRIQVPIEDILPSKEEKSKTPPMFLCIKVGKPMRKSFASHTTAMVQQYGKRRKQPEYWFAVPRERVDHLYTFFVQWSPDVYGKDAKEQGFVVVEKEELNMIDNFFSEPTTKSWEIITVEEAKRRKSTCSYYEEEEEEEEEEGLPILQPHSALLENMHVEQLARCLPARVQGYPWRLAYSTIEHGTSLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPFKFSDHYYGTGETFLYTFSPNFKVFKWSGENSYFINGDISSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKKEDFIVQDLEVWTFE", "length": 948, "header": "tr|A0A061IFG1-1|A0A061IFG1_CRIGR Isoform 1 of Nuclear receptor coactivator 7 isoform X3 OS=Cricetulus griseus OX=10029 GN=Ncoa7 PE=3 SV=1 CANONICAL=A0A061IFG1-1" }, "isoforms": [ { "isoform_ac": "A0A061IFG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IFG1/entry#A0A061IFG1-1", "sequence": { "sequence": "MDTKEEKKEQKERKQSYFARLKKKKQAKQNAEIISATATRSHSGKEDANSVILEQGKSNLAVEGEYSTDEKKKRKNNQLKEIRRTELKRYYSTDDNQSKTHDKKEKKMVVQKPHGTMEYTAGSQDTLNSIALKFNITPNKLVELNKLFTHTIVPGQVLFVPDANFPSSTLRLSSSTPGATVSPSSSDAEYDKLPDADLARKALKPIERVLSSTSEEDEPGVVKFLKMNCRYFTDGKGVVGGVMIVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYNDISHMKIKDALPSDLPQDLCPLYRPGEWEDLASEKDINPFSKFKSINKEKRQQNGERTLTLDPKPMSSPEESGECTHVKPSDSSESWKLKKLEPSRGTASESPSLTQLSKGPSDTHAALESTAKENCLLGEDDDFVDLEELSSQPGSGMDKGDATKERPSYDQKKSEPQTIMSAKKMQVQSSLDLAGLESEAELKGALDLETCEKQDKVHEIDKQSGSPENQVESTLKIHEDLDKVKLIEFYLNKNKDGSQLSENIQRSELKSSKRMEPGGIDITLSSSLPQTGDSPPEGNKEPGTIWVKEKETLPLKLDPSAEENVINNKEALDALGSSLDKSCQGAQMDNKSEIQLWLLKRIQVPIEDILPSKEEKSKTPPMFLCIKVGKPMRKSFASHTTAMVQQYGKRRKQPEYWFAVPRERVDHLYTFFVQWSPDVYGKDAKEQGFVVVEKEELNMIDNFFSEPTTKSWEIITVEEAKRRKSTCSYYEEEEEEEEEEGLPILQPHSALLENMHVEQLARCLPARVQGYPWRLAYSTIEHGTSLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPFKFSDHYYGTGETFLYTFSPNFKVFKWSGENSYFINGDISSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKKEDFIVQDLEVWTFE", "length": 948, "header": "tr|A0A061IFG1-1|A0A061IFG1_CRIGR Isoform 1 of Nuclear receptor coactivator 7 isoform X3 OS=Cricetulus griseus OX=10029 GN=Ncoa7 PE=3 SV=1 CANONICAL=A0A061IFG1-1" }, "locus": {} }, { "isoform_ac": "A0A061IGG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IFG1/entry#A0A061IGG3-1", "sequence": { "sequence": "MDTKEEKKEQKERKQSYFARLKKKKQAKQNAEIISATATRSHSGKEDANSVILEQGKSNLAVEGEYSTDEKKKRKNNQLKEIRRTELKRYYSTDDNQSKTHDKKEKKMVVQKPHGTMEYTAGSQDTLNSIALKFNITPNKLVELNKLFTHTIVPGQVLFVPDANFPSSTLRLSSSTPGATVSPSSSDAEYDKLPDADLARKALKPIERVLSSTSEEDEPGVVKFLKMNCRYFTDGKGVVGGVMIVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYNDISHMKIKDALPSPGEWEDLASEKDINPFSKFKSINKEKRQQNGERTLTLDPKPMSSPEESGECTHVKPSDSSESWKLKKLEPSRGTASESPSLTQLSKGPSDTHAALESTAKENCLLGEDDDFVDLEELSSQPGSGMDKGDATKERPSYDQKKSEPQTIMSAKKMQVQSSLDLAGLESEAELKGALDLETCEKQDKVHEIDKQSGSPENQVESTLKIHEDLDKVKLIEFYLNKNKDGSQLSENIQRSELKSSKRMEPGGIDITLSSSLPQTGDSPPEGNKEPGTIWVKEKETLPLKLDPSAEENVINNKEALDALGSSLDKSCQGAQMDNKSEIQLWLLKRIQVPIEDILPSKEEKSKTPPMFLCIKVGKPMRKSFASHTTAMVQQYGKRRKQPEYWFAVPRERVDHLYTFFVQWSPDVYGKDAKEQGFVVVEKEELNMIDNFFSEPTTKSWEIITVEEAKRRKSTCSYYEEEEEEEEEEGLPILQPHSALLENMHVEQLARCLPARVQGYPWRLAYSTIEHGTSLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPFKFSDHYYGTGETFLYTFSPNFKVFKWSGENSYFINGDISSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKKEDFIVQDLEVWTFE", "length": 937, "header": "tr|A0A061IGG3-1|A0A061IGG3_CRIGR Computationally mapped isoform of Nuclear receptor coactivator 7 isoform X4 OS=Cricetulus griseus OX=10029 GN=Ncoa7 PE=3 SV=1 CANONICAL=A0A061IFG1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J805-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IFG1/entry#A0A9J7J805-1", "sequence": { "sequence": "MDTKEEKKEQKERKQSYFARLKKKKQAKQNAEIISATATRSHSGKEDANSVILEQDDNQSKTHDKKEKKMVVQKPHGTMEYTAGSQDTLNSIALKFNITPNKLVELNKLFTHTIVPGQVLFVPDANFPSSTLRLSSSTPGATVSPSSSDAEYDKLPDADLARKALKPIERVLSSTSEEDEPGVVKFLKMNCRYFTDGKGVVGGVMIVTPNNIMFDPHKSDPLVIENGCEEYGLICPMEEVVSIALYNDISHMKIKDALPSDLPQDLCPLYRPGEWEDLASEKDINPFSKFKSINKEKRQQNGERTLTLDPKPMSSPEESGECTHVKPSDSSESWKLKKLEPSRGTASESPSLTQLSKGPSDTHAALESTAKENCLLGEDDDFVDLEELSSQPGSGMDKGDATKERPSYDQKKSEPQTIMSAKKMQVQSSLDLAGLESEAELKGALDLETCEKQDKVHEIDKQSGSPENQVESTLKIHEDLDKVKLIEFYLNKNKDGSQLSENIQRSELKSSKRMEPGGIDITLSSSLPQTGDSPPEGNKEPGTIWVKEKETLPLKLDPSAEENVINNKEALDALGSSLDKSCQGAQMDNKSEIQLWLLKRIQVPIEDILPSKEEKSKTPPMFLCIKVGKPMRKSFASHTTAMVQQYGKRRKQPEYWFAVPRERVDHLYTFFVQWSPDVYGKDAKEQGFVVVEKEELNMIDNFFSEPTTKSWEIITVEEAKRRKSTCSYYEEEEEEEEEEGLPILQPHSALLENMHVEQLARCLPARVQGYPWRLAYSTIEHGTSLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPFKFSDHYYGTGETFLYTFSPNFKVFKWSGENSYFINGDISSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKKEDFIVQDLEVWTFE", "length": 910, "header": "tr|A0A9J7J805-1|A0A9J7J805_CRIGR Computationally mapped isoform of Oxidation resistance protein 1 OS=Cricetulus griseus OX=10029 GN=Ncoa7 PE=3 SV=1 CANONICAL=A0A061IFG1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IFG1", "url": "https://www.uniprot.org/uniprotkb/A0A061IFG1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IFG1", "url": "https://www.uniprot.org/uniprotkb/A0A061IFG1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773831", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773831", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A061IFG1", "url": "https://www.uniprot.org/uniprotkb/A0A061IFG1" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A061IFG1", "url": "https://www.uniprot.org/uniprotkb/A0A061IFG1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A061IFG1", "url": "https://www.uniprot.org/uniprotkb/A0A061IFG1" } ], "pmid": "" }, { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "A0A061IFG1", "url": "https://www.uniprot.org/uniprotkb/A0A061IFG1" } ], "pmid": "" }, { "name": "negative regulation of cellular response to oxidative stress", "id": "GO:1900408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900408", "evidence": [ { "database": "UniProtKB", "id": "A0A061IFG1", "url": "https://www.uniprot.org/uniprotkb/A0A061IFG1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" }, { "start_pos": 627, "end_pos": 629, "annotation": "n_glycosylation_sequon" }, { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061IFG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IFG1" }, { "id": "PS51782", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51782" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LysM", "eco_id": "ECO_0000259", "start_pos": 117, "end_pos": 160, "start_aa": "Met", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A061IFG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IFG1" }, { "id": "PS51886", "database": "PROSITE", "url": 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This record is derived from a genomic sequence (NW_003614900.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003510578", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510578" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IFW1", "url": "https://www.uniprot.org/uniprotkb/A0A061IFW1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100765661", "url": "https://www.uniprot.org/uniprotkb/A0A061IFW1", "locus": {} } ], "crossref": [ { "id": "100765661", "url": "https://www.ncbi.nlm.nih.gov/gene/100765661", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765661", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765661", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CLYFKIA", "url": "https://omabrowser.org/oma/group/CLYFKIA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061IFW1", "url": "https://www.orthodb.org/?gene=A0A061IFW1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35860", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35860", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35860:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35860:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15193", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15193", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003510578", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510578", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IFW1", "url": "https://www.uniprot.org/uniprotkb/A0A061IFW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IFW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IFW1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFDLRTKVMIGIASSLLVAAIMLIIVVLCLYWKLAKALKMAKEADVENCIGPCKFSQSKINGVKPILAESCPAVQYCDDCSIYTDVGSLPPCFCGTSDGL", "length": 100, "header": "tr|A0A061IFW1-1|A0A061IFW1_CRIGR Isoform 1 of Protein FAM24A OS=Cricetulus griseus OX=10029 GN=LOC100765661 PE=3 SV=1 CANONICAL=A0A061IFW1-1" }, "isoforms": [ { "isoform_ac": "A0A061IFW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IFW1/entry#A0A061IFW1-1", "sequence": { "sequence": "MFDLRTKVMIGIASSLLVAAIMLIIVVLCLYWKLAKALKMAKEADVENCIGPCKFSQSKINGVKPILAESCPAVQYCDDCSIYTDVGSLPPCFCGTSDGL", "length": 100, "header": "tr|A0A061IFW1-1|A0A061IFW1_CRIGR Isoform 1 of Protein FAM24A OS=Cricetulus griseus OX=10029 GN=LOC100765661 PE=3 SV=1 CANONICAL=A0A061IFW1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NW_003614763.1) annotated using gene prediction method: Gnomon. 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"synonym", "evidence": [ { "id": "XP_027263885", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263885" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027263885", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263885" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IFY0", "url": "https://www.uniprot.org/uniprotkb/A0A061IFY0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100764696", "url": "https://www.uniprot.org/uniprotkb/A0A061IFY0", "locus": {} } ], "crossref": [ { "id": "100764696", "url": "https://www.ncbi.nlm.nih.gov/gene/100764696", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764696", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764696", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061IFY0", "url": "https://www.orthodb.org/?gene=A0A061IFY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11736", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11736", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11736:SF163", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11736:SF163", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01454", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01454", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027263885", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263885", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IFY0", "url": "https://www.uniprot.org/uniprotkb/A0A061IFY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IFY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IFY0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLQKPRGRGRPSTQADREREWGDAGEEAPSTSRGTGGTSQGSRASLSSPAVGPRTQKQLEVKVAELVQFLLIKDQKKIPIKRTDILKHVVGDYRDVYPNLLRLAAERLQYVFGYKLVELEPKSHTYILINMLEPVEEDAEVRGDQGTPTTGLLMIVLGLIFMKGNTITETEVWDFLRRLGVYPTKKHLIFGDPKKLITEDFVRQRYLEYRRIPHTDPVDYELQWGPRTNLETSKMKVLKFVAKVHNQDPKDWPTQYCEALADEENRARPAASAPTTSS", "length": 278, "header": "tr|A0A061IFY0-1|A0A061IFY0_CRIGR Isoform 1 of Non-structural maintenance of chromosomes element 3 homolog OS=Cricetulus griseus OX=10029 GN=LOC100764696 PE=4 SV=1 CANONICAL=A0A061IFY0-1" }, "isoforms": [ { "isoform_ac": "A0A061IFY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IFY0/entry#A0A061IFY0-1", "sequence": { "sequence": "MLQKPRGRGRPSTQADREREWGDAGEEAPSTSRGTGGTSQGSRASLSSPAVGPRTQKQLEVKVAELVQFLLIKDQKKIPIKRTDILKHVVGDYRDVYPNLLRLAAERLQYVFGYKLVELEPKSHTYILINMLEPVEEDAEVRGDQGTPTTGLLMIVLGLIFMKGNTITETEVWDFLRRLGVYPTKKHLIFGDPKKLITEDFVRQRYLEYRRIPHTDPVDYELQWGPRTNLETSKMKVLKFVAKVHNQDPKDWPTQYCEALADEENRARPAASAPTTSS", "length": 278, "header": "tr|A0A061IFY0-1|A0A061IFY0_CRIGR Isoform 1 of Non-structural maintenance of chromosomes element 3 homolog OS=Cricetulus griseus OX=10029 GN=LOC100764696 PE=4 SV=1 CANONICAL=A0A061IFY0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007647660", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007647660" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IGM6", "url": "https://www.uniprot.org/uniprotkb/A0A061IGM6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "CUNH4orf33", "url": "https://www.uniprot.org/uniprotkb/A0A061IGM6", "locus": {} } ], "crossref": [ { "id": "100771610", "url": "https://www.ncbi.nlm.nih.gov/gene/100771610", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "cge:100771610", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771610", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TIFGEEW", "url": "https://omabrowser.org/oma/group/TIFGEEW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061IGM6", "url": "https://www.orthodb.org/?gene=A0A061IGM6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31475", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31475", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31475:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31475:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_007647660", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007647660", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IGM6", "url": "https://www.uniprot.org/uniprotkb/A0A061IGM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IGM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IGM6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KD81", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KD81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KD81-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KD81-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFKIEYTWDGFPVKHEPVCVKLSSGDKGVKMEVSAPFFNDPLTPLGEPGKPFSELWNYEVVEAFFLNDTTEQYLEVELCPHGQHLVLLLSGRRNVWKKELPLSFKVFRGETNWEGIAFLPWSYFPPNVTKFNSFAIHGSNDQRSYEALYPVPQHELQQGQKPDFHRLEYFKPFSFNTLLGEEWKQPESDLWLIEKPDM", "length": 199, "header": "tr|A0A061IGM6-1|A0A061IGM6_CRIGR Isoform 1 of UPF0462 protein C4orf33 homolog isoform X1 OS=Cricetulus griseus OX=10029 GN=CUNH4orf33 PE=3 SV=1 CANONICAL=A0A061IGM6-1" }, "isoforms": [ { "isoform_ac": "A0A061IGM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IGM6/entry#A0A061IGM6-1", "sequence": { "sequence": "MDFKIEYTWDGFPVKHEPVCVKLSSGDKGVKMEVSAPFFNDPLTPLGEPGKPFSELWNYEVVEAFFLNDTTEQYLEVELCPHGQHLVLLLSGRRNVWKKELPLSFKVFRGETNWEGIAFLPWSYFPPNVTKFNSFAIHGSNDQRSYEALYPVPQHELQQGQKPDFHRLEYFKPFSFNTLLGEEWKQPESDLWLIEKPDM", "length": 199, "header": "tr|A0A061IGM6-1|A0A061IGM6_CRIGR Isoform 1 of UPF0462 protein C4orf33 homolog isoform X1 OS=Cricetulus griseus OX=10029 GN=CUNH4orf33 PE=3 SV=1 CANONICAL=A0A061IGM6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KD81-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IGM6/entry#A0A9J7KD81-1", "sequence": { "sequence": "MDFKIEYTWDGFPVKHEPVCVKLSSGDKGVKMEVSAPFFNDPLTPLGEPGKPFSELWNYEVVEAFFLNDTTEQYLEVELCPHGQHLVLLLSGRRNVWKKELPLSFKVFRGETNWEGIAFLPWSYFPPNVTKFNSFAIHGSNDQRSYEALYPVPQHELQQGQKPDLIIQNNFTSEGKKRVYKRWQMALKH", "length": 189, "header": "tr|A0A9J7KD81-1|A0A9J7KD81_CRIGR Computationally mapped isoform of UPF0462 protein C4orf33 homolog isoform X2 OS=Cricetulus griseus OX=10029 GN=CUNH4orf33 PE=3 SV=1 CANONICAL=A0A061IGM6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IGM6", "url": "https://www.uniprot.org/uniprotkb/A0A061IGM6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IGM6", "url": "https://www.uniprot.org/uniprotkb/A0A061IGM6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771610", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771610", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XYF2-1", "protein_name": "CD033 protein", "gene_name": "C4orf33", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQNTKMELRIEHTWDGLPVSHDPVTIALKSYDAGLLMQVSAPFFNDPPAPLGEPGKPFRKLWDYEVVEAFFLSDRSEQYLEVELCPHGQHLLLLLSGKRRVWKEELPLEFDVTRTETKWEGTAHLPWNYFPPGTSKFNAYAIYGSGEHRKYEALYPVPRHKLQEGQKPDFHRLEFFQELNLKELMGEDWKQPESHLWKSHTE", "length": 202 }, "evidence": [ { "id": "A0A061IGM6", "url": "https://omabrowser.org/oma/group/A0A061IGM6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1RRC4-1", "protein_name": "Chromosome 4 open reading frame 33", "gene_name": "C4orf33", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDFKIEHTWDSFPVKHEPVFVRLNPGDRGVMMEVSAPFFNDPPAPLGEPGKPFNELWDYEVVEAFFLNDMTEQYLEVELCPHGQHLVLLLSGRRNVWKQELDLSFKVYRGETKWEGRAYLPWSYFPPNVTKFNSFAIHGSKDKRSYEALYPVPQHEIQQGQKPDFHRLEYFKPFSFNVLLGEEWKQPESDLWLTEKPDV", "length": 199 }, "evidence": [ { "id": "A0A061IGM6", "url": "https://omabrowser.org/oma/group/A0A061IGM6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5M845-1", "protein_name": "UPF0462 protein C4orf33 homolog", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDFKIEYTWDSFPVSHEPVRIRLNPCDKGLKMEVSAPFFNDPPAPLGEPGKPFSELWNYEVVEAFFLNNTTEQYLEVELCPHGQHLVLLLSGRRNVWKKELALSFKVSRGETHWEGEAFLPWSYFPSKVTRFNSFAIHGSNDKRVYEALYPVPQPELQQGQNPDFHRLEYFKPFSFNTLLGEEWKQPESDLWLIEKSDI", "length": 199 }, "evidence": [ { "id": "A0A061IGM6", "url": "https://omabrowser.org/oma/group/A0A061IGM6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BGN2-1", "protein_name": "UPF0462 protein C4orf33 homolog", "gene_name": "D3Ertd751e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFKIEYTWDGFPVRHEPVCVRLSPCEQGVKMEVSAPLFNDPPSPLGEPGKPFSELWNYEVVEAFFLNDTTKQYLEVELCPHGQHLVLLLAGRRNVWKKELPLSFKASRGGTNWEGEAYIPWSYFPPNVTKFNSFAIHGSNDRRVYEALYPVPQHELQQGQKPDFHRLEYFKPFSFNTLLGEEWRQPEPDLW", "length": 192 }, "evidence": [ { "id": "A0A061IGM6", "url": "https://omabrowser.org/oma/group/A0A061IGM6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N1A6-1", "protein_name": "UPF0462 protein C4orf33", "gene_name": "C4orf33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDFKIEHTWDGFPVKHEPVFIRLNPGDRGVMMDISAPFFRDPPAPLGEPGKPFNELWDYEVVEAFFLNDITEQYLEVELCPHGQHLVLLLSGRRNVWKQELPLSFRMSRGETKWEGKAYLPWSYFPPNVTKFNSFAIHGSKDKRSYEALYPVPQHELQQGQKPDFHCLEYFKSFNFNTLLGEEWKQPESDLWLIEKCDI", "length": 199 }, "evidence": [ { "id": "A0A061IGM6", "url": "https://omabrowser.org/oma/group/A0A061IGM6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 68, "end_pos": 70, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 }, { "start_pos": 68, "end_pos": 70 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061IGN2-1", "uniprot_ac": "A0A061IGN2", "uniprot_id": "A0A061IGN2_CRIGR", "mass": { "chemical_mass": 48128.0, "monoisotopic_mass": 48128.0 }, "refseq": { "ac": "XP_027263423", "name": "coiled-coil domain-containing protein 83 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263423" }, "gene_names": [ { "name": "Ccdc83", "type": "recommended", "evidence": [ { "id": "A0A061IGN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IGN2" } ] }, { "name": "Ccdc83", "type": "synonym", "evidence": [ { "id": "XP_027263423", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263423" } ] } ], "protein_names": [ { "name": "Coiled-coil domain-containing protein 83 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A061IGN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IGN2/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 83 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027263423", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263423" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027263423", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263423" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IGN2", "url": "https://www.uniprot.org/uniprotkb/A0A061IGN2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ccdc83", "url": "https://www.uniprot.org/uniprotkb/A0A061IGN2", "locus": {} } ], "crossref": [ { "id": "100763604", "url": "https://www.ncbi.nlm.nih.gov/gene/100763604", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026702", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026702", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763604", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763604", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061IGN2", "url": "https://www.orthodb.org/?gene=A0A061IGN2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21468", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21468", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21468:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21468:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_027263423", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263423", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IGN2", "url": "https://www.uniprot.org/uniprotkb/A0A061IGN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IGN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IGN2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSSAKGGKKEAQDITTKDGKLPMSEALLDYHREIKENAVERFMFHIKKLRDKNQRYHDRNRRLKDEQKWHVKNLLKELTEEKAEGVPAITREEVEEAMKEKWQFERDQEKNLKEMRIQINDAEKLFLEKLSEKEYWEEYKNVGSEQHAQLIISLQNDIKTVKENAEKMSEQYKINLEDTRKRIIRETLIQMDLRKEWATQNAVKFVDRGNYREVWENDWLKKEISIHKKEVEKLENCIHELEKENLVLIEQLFNCKLVDLKIPRKLYSTQAAGQQELPEDVASLKLPELDKDSEENLKSPTEARDEASLLPGSSKEASIPEVQLEQTDRGDSSSIEIKGSVIHYLLHEDEQDFKDYVKLGPLALKLMSVEGKKMPIHFQEKETPLITYEDLKVPDNHITHKMMKSFL", "length": 408, "header": "tr|A0A061IGN2-1|A0A061IGN2_CRIGR Isoform 1 of Coiled-coil domain-containing protein 83 isoform X2 OS=Cricetulus griseus OX=10029 GN=Ccdc83 PE=4 SV=1 CANONICAL=A0A061IGN2-1" }, "isoforms": [ { "isoform_ac": "A0A061IGN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IGN2/entry#A0A061IGN2-1", "sequence": { "sequence": "MDSSAKGGKKEAQDITTKDGKLPMSEALLDYHREIKENAVERFMFHIKKLRDKNQRYHDRNRRLKDEQKWHVKNLLKELTEEKAEGVPAITREEVEEAMKEKWQFERDQEKNLKEMRIQINDAEKLFLEKLSEKEYWEEYKNVGSEQHAQLIISLQNDIKTVKENAEKMSEQYKINLEDTRKRIIRETLIQMDLRKEWATQNAVKFVDRGNYREVWENDWLKKEISIHKKEVEKLENCIHELEKENLVLIEQLFNCKLVDLKIPRKLYSTQAAGQQELPEDVASLKLPELDKDSEENLKSPTEARDEASLLPGSSKEASIPEVQLEQTDRGDSSSIEIKGSVIHYLLHEDEQDFKDYVKLGPLALKLMSVEGKKMPIHFQEKETPLITYEDLKVPDNHITHKMMKSFL", "length": 408, "header": "tr|A0A061IGN2-1|A0A061IGN2_CRIGR Isoform 1 of Coiled-coil domain-containing protein 83 isoform X2 OS=Cricetulus griseus OX=10029 GN=Ccdc83 PE=4 SV=1 CANONICAL=A0A061IGN2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IGN2", "url": "https://www.uniprot.org/uniprotkb/A0A061IGN2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027260434", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260434" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IGU2", "url": "https://www.uniprot.org/uniprotkb/A0A061IGU2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ypel3", "url": "https://www.uniprot.org/uniprotkb/A0A061IGU2", "locus": {} } ], "crossref": [ { "id": "100770652", "url": "https://www.ncbi.nlm.nih.gov/gene/100770652", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770652", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770652", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061IGU2", "url": "https://www.orthodb.org/?gene=A0A061IGU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13848", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13848", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027260434", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260434", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IGU2", "url": "https://www.uniprot.org/uniprotkb/A0A061IGU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IGU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IGU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FL02", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FL02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FL02-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FL02-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GXD3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GXD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GXD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GXD3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQPEASSALGSLCSPWAAPRVGPLPLAPAMVRISKPKTFQAYLDDCHRRYSCAHCRAHLANHDDLISKSFQGSQGRAYLFNSVVNVGCGPAEERVLLTGLHAVADIHCENCKTTLGWKYEQAFESSQKYKEGKYIIELNHMIKDNGWD", "length": 148, "header": "tr|A0A061IGU2-1|A0A061IGU2_CRIGR Isoform 1 of Protein yippee-like OS=Cricetulus griseus OX=10029 GN=Ypel3 PE=3 SV=1 CANONICAL=A0A061IGU2-1" }, "isoforms": [ { "isoform_ac": "A0A061IGU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IGU2/entry#A0A061IGU2-1", "sequence": { "sequence": "MQPEASSALGSLCSPWAAPRVGPLPLAPAMVRISKPKTFQAYLDDCHRRYSCAHCRAHLANHDDLISKSFQGSQGRAYLFNSVVNVGCGPAEERVLLTGLHAVADIHCENCKTTLGWKYEQAFESSQKYKEGKYIIELNHMIKDNGWD", "length": 148, "header": "tr|A0A061IGU2-1|A0A061IGU2_CRIGR Isoform 1 of Protein yippee-like OS=Cricetulus griseus OX=10029 GN=Ypel3 PE=3 SV=1 CANONICAL=A0A061IGU2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FL02-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IGU2/entry#A0A9J7FL02-1", "sequence": { "sequence": "MYGLGPHSPPLLPDRHWAPSARRGPLPAWGHCPWPPPWCGFQSPRRFRPTWMIVTGGIAVPTAVPTWLTTTTSSPRVNVGCGPAEERVLLTGLHAVADIHCENCKTTLGWKYEQAFESSQKYKEGKYIIELNHMIKDNGWD", "length": 141, "header": "tr|A0A9J7FL02-1|A0A9J7FL02_CRIGR Computationally mapped isoform of Protein yippee-like OS=Cricetulus griseus OX=10029 GN=Ypel3 PE=3 SV=1 CANONICAL=A0A061IGU2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GXD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IGU2/entry#A0A9J7GXD3-1", "sequence": { "sequence": "MIVTGGIAVPTAVPTWLTTTTSSPRVNVGCGPAEERVLLTGLHAVADIHCENCKTTLGWKYEQAFESSQKYKEGKYIIELNHMIKDNGWD", "length": 90, "header": "tr|A0A9J7GXD3-1|A0A9J7GXD3_CRIGR Computationally mapped isoform of Protein yippee-like OS=Cricetulus griseus OX=10029 GN=Ypel3 PE=3 SV=1 CANONICAL=A0A061IGU2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061IGU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IGU2" }, { "id": "PS51792", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51792" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Yippee", "eco_id": "ECO_0000259", "start_pos": 48, "end_pos": 145, "start_aa": "Arg", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"A0A061IGV6", "uniprot_id": "A0A061IGV6_CRIGR", "mass": { "chemical_mass": 15518.0, "monoisotopic_mass": 15518.0 }, "refseq": { "ac": "XP_003504479", "name": "transmembrane protein 60", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504479" }, "gene_names": [ { "name": "Tmem60", "type": "recommended", "evidence": [ { "id": "A0A061IGV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IGV6" } ] }, { "name": "Tmem60", "type": "synonym", "evidence": [ { "id": "XP_003504479", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504479" } ] } ], "protein_names": [ { "name": "Transmembrane protein 60", "type": "synonym", "evidence": [ { "id": "A0A061IGV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IGV6/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 60", "type": "synonym", "evidence": [ { "id": "XP_003504479", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504479" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614067.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003504479.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003504479", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504479" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IGV6", "url": "https://www.uniprot.org/uniprotkb/A0A061IGV6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tmem60", "url": "https://www.uniprot.org/uniprotkb/A0A061IGV6", "locus": {} } ], "crossref": [ { "id": "100757990", "url": "https://www.ncbi.nlm.nih.gov/gene/100757990", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019396", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019396", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757990", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757990", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RTHWNWF", "url": "https://omabrowser.org/oma/group/RTHWNWF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061IGV6", "url": "https://www.orthodb.org/?gene=A0A061IGV6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13568", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13568", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13568:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13568:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10269", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10269", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003504479", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504479", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IGV6", "url": "https://www.uniprot.org/uniprotkb/A0A061IGV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IGV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IGV6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRMSLAQRVLLTWLFTLLFLIMLVLKLDEKAPWNWFLIFIPVWIFDTILLVMLIVKMAGRCKSGFDPRHGSHNIKKKAWYLIAMLLKLAFCLALCAKLEQFTTMNLSYVFIPLWALLAGALTELGYNVFFVRD", "length": 133, "header": "tr|A0A061IGV6-1|A0A061IGV6_CRIGR Isoform 1 of Transmembrane protein 60 OS=Cricetulus griseus OX=10029 GN=Tmem60 PE=4 SV=1 CANONICAL=A0A061IGV6-1" }, "isoforms": [ { "isoform_ac": "A0A061IGV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IGV6/entry#A0A061IGV6-1", "sequence": { "sequence": "MRMSLAQRVLLTWLFTLLFLIMLVLKLDEKAPWNWFLIFIPVWIFDTILLVMLIVKMAGRCKSGFDPRHGSHNIKKKAWYLIAMLLKLAFCLALCAKLEQFTTMNLSYVFIPLWALLAGALTELGYNVFFVRD", "length": 133, "header": "tr|A0A061IGV6-1|A0A061IGV6_CRIGR Isoform 1 of Transmembrane protein 60 OS=Cricetulus griseus OX=10029 GN=Tmem60 PE=4 SV=1 CANONICAL=A0A061IGV6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IGV6", "url": "https://www.uniprot.org/uniprotkb/A0A061IGV6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IGV6", "url": "https://www.uniprot.org/uniprotkb/A0A061IGV6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757990", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757990", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AK80-1", "protein_name": "Transmembrane protein 60", "gene_name": "TMEM60", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRMSLAQRVLLTWLFTLLFLIMLVLKLDEKAPWNWFLIFIPVWIFDTILLVMLIVKMAGRCKSGFDPRHGSHNIKKKAWYLIAMLLKLAFCLALCAKLEQFTTMNLSYVFIPLWALLAGALIELGYNVFFVRD", "length": 133 }, "evidence": [ { "id": "A0A061IGV6", "url": "https://omabrowser.org/oma/group/A0A061IGV6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { 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This record is derived from a genomic sequence (NW_003613875.1) annotated using gene prediction method: Gnomon. 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF17919", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17921", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17921", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23050", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23050", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23052", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23052", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003502130", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502130", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IH38", "url": "https://www.uniprot.org/uniprotkb/A0A061IH38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IH38-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IH38-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], 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"length": 1892, "header": "tr|A0A061IH38-1|A0A061IH38_CRIGR Isoform 1 of Protein NYNRIN OS=Cricetulus griseus OX=10029 GN=Nynrin PE=4 SV=1 CANONICAL=A0A061IH38-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 600, "start_aa": "Thr", "end_pos": 600, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr600", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 636, "start_aa": "Thr", "end_pos": 636, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr636", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IH38", "url": "https://www.uniprot.org/uniprotkb/A0A061IH38" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IH38", "url": "https://www.uniprot.org/uniprotkb/A0A061IH38" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768139", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768139", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A061IH38", "url": "https://www.uniprot.org/uniprotkb/A0A061IH38" } ], "pmid": "" }, { "name": "RNA-DNA hybrid ribonuclease activity", "id": "GO:0004523", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004523", "evidence": [ { "database": "UniProtKB", "id": "A0A061IH38", "url": "https://www.uniprot.org/uniprotkb/A0A061IH38" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A061IH38", "url": "https://www.uniprot.org/uniprotkb/A0A061IH38" } ], "pmid": "" }, { "name": "cytoplasmic ribonucleoprotein granule", "id": "GO:0036464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036464", "evidence": [ { "database": "UniProtKB", "id": "A0A061IH38", "url": "https://www.uniprot.org/uniprotkb/A0A061IH38" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA integration", "id": "GO:0015074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015074", "evidence": [ { "database": "UniProtKB", "id": "A0A061IH38", "url": "https://www.uniprot.org/uniprotkb/A0A061IH38" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { 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"categories": [ "Protein Classification" ] }, { "id": "PTHR12072", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12072", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12072:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12072:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04676", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04676", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04677", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04677", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003508494", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508494", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IHC6", "url": "https://www.uniprot.org/uniprotkb/A0A061IHC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IHC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IHC6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GWP6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GWP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GWP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GWP6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQQPLRLLACGDVDGKFDVLFNRVRTIQKKSGNFDLLLCVGNFFGSTQDAEWEEYKTGKKKAPIQTYVLGANNPETVQYFQDTDGCELAENITYLGRKGFFTGSSGLQIVYLSGTESLSEPVPSHSFSPKDVSSLRTMLCSASQFKGVDILLTSPWPKYVGNFGNSSGEVDTKKCGSALISSLAASLKPRYHFAALEKSYYERLPYRNHVVLQESTQHATRFIALANVGNAEKKKYLYAFSIVPMKLMAAAELVKQPPDVTENPYRESGKAAAIGKHVPAPQEEPACQFFFDLNEKQGRKRSSTGRDSKSPQAKQPRRPPQPPGPCWFCLASPEVEKHLVVNIGTHCYLALAKGGLSDDHVLILPIGHYQSVVELSAEVVEEVEKYKATLKRFFKSRGKRCVLFERNYRSHHLQLQVIPVPLSCCVTDDIKDAFITQAQEQQIELLEIPEHSDIKQIAQPGAAYFYVELDTGEKLFHRIKKNFPLQFGREVLASEAILNIPDKADWRQCQISKEEEETLARRFRKDFEPFDFTLDD", "length": 537, "header": "tr|A0A061IHC6-1|A0A061IHC6_CRIGR Isoform 1 of CWF19-like protein 1 OS=Cricetulus griseus OX=10029 GN=Cwf19l1 PE=3 SV=1 CANONICAL=A0A061IHC6-1" }, "isoforms": [ { "isoform_ac": "A0A061IHC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IHC6/entry#A0A061IHC6-1", "sequence": { "sequence": "MAQQPLRLLACGDVDGKFDVLFNRVRTIQKKSGNFDLLLCVGNFFGSTQDAEWEEYKTGKKKAPIQTYVLGANNPETVQYFQDTDGCELAENITYLGRKGFFTGSSGLQIVYLSGTESLSEPVPSHSFSPKDVSSLRTMLCSASQFKGVDILLTSPWPKYVGNFGNSSGEVDTKKCGSALISSLAASLKPRYHFAALEKSYYERLPYRNHVVLQESTQHATRFIALANVGNAEKKKYLYAFSIVPMKLMAAAELVKQPPDVTENPYRESGKAAAIGKHVPAPQEEPACQFFFDLNEKQGRKRSSTGRDSKSPQAKQPRRPPQPPGPCWFCLASPEVEKHLVVNIGTHCYLALAKGGLSDDHVLILPIGHYQSVVELSAEVVEEVEKYKATLKRFFKSRGKRCVLFERNYRSHHLQLQVIPVPLSCCVTDDIKDAFITQAQEQQIELLEIPEHSDIKQIAQPGAAYFYVELDTGEKLFHRIKKNFPLQFGREVLASEAILNIPDKADWRQCQISKEEEETLARRFRKDFEPFDFTLDD", "length": 537, "header": "tr|A0A061IHC6-1|A0A061IHC6_CRIGR Isoform 1 of CWF19-like protein 1 OS=Cricetulus griseus OX=10029 GN=Cwf19l1 PE=3 SV=1 CANONICAL=A0A061IHC6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GWP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IHC6/entry#A0A9J7GWP6-1", "sequence": { "sequence": "MLCSASQFKGVDILLTSPWPKYVGNFGNSSGEVDTKKCGSALISSLAASLKPRYHFAALEKSYYERLPYRNHVVLQESTQHATRFIALANVGNAEKKKYLYAFSIVPMKLMAAAELVKQPPDVTENPYRESGKAAAIGKHVPAPQEEPACQFFFDLNEKQGRKRSSTGRDSKSPQAKQPRRPPQPPGPCWFCLASPEVEKHLVVNIGTHCYLALAKGGLSDDHVLILPIGHYQSVVELSAEVVEEVEKYKATLKRFFKSRGKRCVLFERNYRSHHLQLQVIPVPLSCCVTDDIKDAFITQAQEQQIELLEIPEHSDIKQIAQPGAAYFYVELDTGEKLFHRIKKNFPLQFGREVLASEAILNIPDKADWRQCQISKEEEETLARRFRKDFEPFDFTLDD", "length": 399, "header": "tr|A0A9J7GWP6-1|A0A9J7GWP6_CRIGR Computationally mapped isoform of CWF19-like protein 1 OS=Cricetulus griseus OX=10029 GN=Cwf19l1 PE=3 SV=1 CANONICAL=A0A061IHC6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IHC6", "url": "https://www.uniprot.org/uniprotkb/A0A061IHC6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IHC6", "url": "https://www.uniprot.org/uniprotkb/A0A061IHC6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751475", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751475", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1U4C8-1", "protein_name": "CWF19-like protein 1", "gene_name": "CWF19L1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAQKPLRLLACGDVEGKFDILFNRVRAIQKKSGNFDLLLCVGNFFGSTPDTEWEEYKTGVKKAPIQTYVLGANNQETVKYFQDVDGCELAENITYLGRKGIFTGSSGLQIVYLSGTESLNEPVPGYSFSPKDVSSLRMMLCSTPQFKGVDILLTSPWPKYVGNFGNSSGEVDTKKCGSALISSLAAGLKPRYHFAALEKTYYERLPYRNHIVLQENAQHATRFIALANVGNPEKKKYLYAFSIVPMKLMDAAELVKQPPDVTENPYRKSGKEASIGKQIPAPEEESACQFFFDLNEKQGRKRSSTGRDTKSSPHPKQPRKPPQPPGPCWFCLASPEVEKHLVVNIGTHCYLALAKGGLSDDHVLILPIGHYQSVVELSAEVVEEVEKYKATLRRFFKSRGKRCVLFERNYKSHHLQLQVIPVPLSRCATDDIKDAFITQAQEQQIELLEIPEHSDIKQIAQPGAAYFYVELDTGEKLFHRIKKNFPLQFGREVLASEAILNIPDKSDWRQCQISKEEEETLARRFRKDFEPFDFTLDD", "length": 538 }, "evidence": [ { "id": "A0A061IHC6", "url": "https://omabrowser.org/oma/group/A0A061IHC6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A1Z8J0-1", "protein_name": "CWF19-like protein 1 homolog", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHQVGSTNMMKIQSIAQLSITMDAGTKILVVGDVRGRFKQLFQRVEQVNKKAGPFEILCCVGDFFGEDKQNEELIAYKNGFKHITVPTYILGPNQREHEKYFENLTDGEICTNLTYLGRRGVYTLSSGVKIAYLSGLEAQGTADSAGSEHEFTKADVIAVRNSCLVSKNCSTEYRGVDVLLTSQWPFGMQEKENATASKLVSFLCREIKPRYHFCAINGTHYESAPFRMPKDETTQFELCTRFISLAEVGNAEKAKYIYALSLKPVDKSRLLDLAQKTTNEIPCPFIGLDLGGAIGKNDSSENRQYFYDMDGGRRKRQGGDNNKRDKRPRIPQIEQDKCWFCLSSPDVEKHLIITVGEHFYLALAKGPINKHHVMILSTKHVPCAAQLSPDDWKELNKFKAALRKFFKTLGQVVCFTERHYKSVHLQINALAFEEGYAWKIKHSFEDKAEEFNLEFETLPALDSEKMLPEMGPYFLAELPDDSTLITRQMKHFPIHFARDVFCSENLLNCDEKVNWKDCLLDKDEEVAYVEDFRKAFAPFDFTDD", "length": 545 }, "evidence": [ { "id": "A0A061IHC6", "url": "https://omabrowser.org/oma/group/A0A061IHC6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "D3Z863-1", "protein_name": "CWF19-like protein 1", "gene_name": "Cwf19l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQKPLRLLACGDVEGKFDVLFNRVRTIQKKSGNFDLLLCVGNFFGSTQDAAWEEYRTGSKKAPIQTYVLGANNQETANYFQDADGCELAENITYLGRKGVFTGSSGLQIVYLSGTESLDEPVPAYSFSPKDVSSLRTMLCSAPQFKGVDILLTSPWPKYVGSFGNSSGEVDTKQCGSALISSLAVSLKPRYHFAALEKSYYERLPYRNHVVLQESAQHATRFIALANVGNPEKKKYLYAFSIVPMKLMAVAELVKQPPDVTENPYRESGKQAAAGKQIPAPQEESACQFFFDLNEKQGRKRSSTGRDNKPPHAKHPRKPPQPPGPCWFCLASPEVEKHLVVNIGTHCYLALAKGGLSDDHVLILPIGHYQSVVELSAEVVEEVEKYKDTLKRFFKSRGKRCVLFERNYKSHHLQLQVIPVPLSCCVTDDIKDAFITQAQEQQIELLEIPEHSDIKQIAQPGAAYFYVELDTGEKLFHRIKKNFPLQFGREVLASEAILNIPEKADWRQCQTSKDEEEALARRFRKDFEPFDFTLDD", "length": 537 }, "evidence": [ { "id": "A0A061IHC6", "url": "https://omabrowser.org/oma/group/A0A061IHC6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54NJ5-1", "protein_name": "CwfJ family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METHKILVCGDIGGSFNALFKRVSTVNKSNGPFSLLLCVGSFFEPYHPTTNISNENNNNSNDADDKDENNNDNDNNNNNNNNNNSDDKDENELTFPKELQPYKDEIENVPIPTYFIAYSQSDFKYIKKFVNKETGELCKGITYLGKCGIKNISNLNIAYLSGKIDYPIKIQSNEENTIIKSEIDNIIKEGEDKRIDILLSNQWSRGVLNNVTSGIPTFLKTPYKIGIDGVKLVSQALTPAYHFSKNSFYFQRAPYYNTPTLKNKNPQPTRFLSLAPINNDKKEKYLFAMSYNPNKDINKDDITPNPFERKQRELDEHVSKKQRNSDEQQTNFFFNNTNNNYNNNNNRNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNYNNNYNKRINNQQQQQQQLKQKHQDQSCWFCLSSPEVDSHLIVTIGDECYLAFPKGGMVEHNLLIVFTEHKPNFMSLNEEERKDVNLMIDYLREYFLDKYNQDIVIFERSISTKGGTDLHGHLQVIPIPKELSSTVKQSFIDHPLTKKYNMEFNDFKNDENSGKELKDKPYYLVFLPNSEQIYSVISKPDFQYGRKVMVDLLGIPEKLNWKDCVKTKEIETSETLKFRDEFQPFYDKKQPTDDDNNEDNTQ", "length": 630 }, "evidence": [ { "id": "A0A061IHC6", "url": "https://omabrowser.org/oma/group/A0A061IHC6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5RGJ5-1", "protein_name": "CWF19-like protein 1", "gene_name": "cwf19l1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGDKPLRVLACGDVEGRINALFNRVNAIQKKSGQFDLLLCVGDFFGSSPEAEAEWATYKSGAKKAPIHTCILGAASQETVKYFPSSDGCELAENITCLGRRGIFTGASGLQIAYVSGREAHQEPAPSHCFTPKDITALVAPLLSNSKFRGVDILLTSQWPRGVCQYGNSPETDMKFCGVSSIADLADKLKPRYHFAGLEGVHYERLPYRNHVVLQENTQHVSRFIALATVNNPAKKKYLYAFNIIPMKNMDSTELVKQPQDVTENPYRKLMKDGKKERQSASMTDAQEEPASQFFFDLGQKNPQRQHGRKRQSDGDRPNQHKQPRRPPQPTGPCWFCLASPEVEKHLVISIGTHCYMALAKGGLTPDHVLLLPIGHYQSVVDLASEVVEEMEKYKSAFKKFCKSKGKRCVLFERNYRSQHLQLQAVPVPMEKCSTEDIKEAFMTQAEEQQMELMEIPAHTDLKQIAPPGTPYFYVELDTGDKLFYRIKKNFPLQFGREVLASEAVMNIPMRSDWRECKISREEEEDQAKQVRSDYEPFDFALDD", "length": 544 }, "evidence": [ { "id": "A0A061IHC6", "url": "https://omabrowser.org/oma/group/A0A061IHC6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q69YN2-1", "protein_name": "CWF19-like protein 1", "gene_name": "CWF19L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQKPLRLLACGDVEGKFDILFNRVQAIQKKSGNFDLLLCVGNFFGSTQDAEWEEYKTGIKKAPIQTYVLGANNQETVKYFQDADGCELAENITYLGRKGIFTGSSGLQIVYLSGTESLNEPVPGYSFSPKDVSSLRMMLCTTSQFKGVDILLTSPWPKCVGNFGNSSGEVDTKKCGSALVSSLATGLKPRYHFAALEKTYYERLPYRNHIILQENAQHATRFIALANVGNPEKKKYLYAFSIVPMKLMDAAELVKQPPDVTENPYRKSGQEASIGKQILAPVEESACQFFFDLNEKQGRKRSSTGRDSKSSPHPKQPRKPPQPPGPCWFCLASPEVEKHLVVNIGTHCYLALAKGGLSDDHVLILPIGHYQSVVELSAEVVEEVEKYKATLRRFFKSRGKWCVVFERNYKSHHLQLQVIPVPISCSTTDDIKDAFITQAQEQQIELLEIPEHSDIKQIAQPGAAYFYVELDTGEKLFHRIKKNFPLQFGREVLASEAILNVPDKSDWRQCQISKEDEETLARRFRKDFEPYDFTLDD", "length": 538 }, "evidence": [ { "id": "A0A061IHC6", "url": "https://omabrowser.org/oma/group/A0A061IHC6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q84WU9-1", "protein_name": "Zinc finger CCCH domain-containing protein 64", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAPRILLCGDPLGRLNQLFKRVQSVSKSAGPFDALICVGQFFPDSPEILDEFLDYVEGRAQVPIPTYFTGDYGVVAPKILSTTSKKAENQGFKMDGLEVCHNLFWLRGSGKFSLHGLSVAYLSGRQSSESQFGKYSQDDVDALRALAEEPGGVDLFLTNEWPAGVTNRAAVSDIPVGISDSSCSDSTVSELVMEVKPRYHIAGSMGVFYAREPYLNAESTHVTRFIGLAQVGNKNKQKFLHALSPTPTSTMSPAELSAKPPKTTLWPYNLQDGAAESKKRPNDSDSDSQYWRYDVPKRQKSGSQGEKLCFKFVCSGSCPRGEDCHFQHNAEAREQCRRGVCLDLIIKGKCEKGPECSYKHEFQDESSIQRKPRSENANRSKECWFCLSSPSVESHLIVSVGESFYCALPKGSLVEDHILIIPIEHLPNTLVLSPEVESELSRYQNGLRNCYKSQGNDAVFFELVSKRVSHANLQVVPVPSSRARLLPNIFSLAAEKLGFKLVTKKFNDSTDGRKYLQKEYNAALGLFYVELPDGTVLSHTLEENEVFPAQFGREVLAGLLKIPDRADWRNCKISQEEEAKLAEDFKKQFQEFDPCQ", "length": 596 }, "evidence": [ { "id": "A0A061IHC6", "url": "https://omabrowser.org/oma/group/A0A061IHC6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8CI33-1", "protein_name": "CWF19-like protein 1", "gene_name": "Cwf19l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQKPLRLLACGDVEGKFDVLFNRVRTIQKKSGNFDLLLCVGNFFGSAQDAEWEEYKTGNKKAPIQTYVLGANNEETANYFQGADGCELAENITYLGRKGVFTGSSGLQIVYLSGTESLDEPVPAHSFSPKDVSSLRTMLCSASQFKGVDILLTSPWPKYVGSFGNSSGEVDTKNCGSALISSLAVSLKPRYHFAALEKSYYERLPYRNHVVLQESAQHATRFIALANVGNPEKKKYLYAFSIVPMKLMAVAELVKQPPDVTENPYRDSGKQAAGGKHIPAPQEESACQFFFDLSEKQGRKRPSTGRDTRPPHAKQPRKPPQPPGPCWFCLASPEVEKHLVVNIGTHCYLALAKGGLSDDHVLILPIGHYQSVVELSAEVVEEVEKYKATLQRFFKSRGKRCVLFERNYRSHHLQLQVIPVPLSCCATDDIKDAFITQAQEQQIELLEIPEHSDIKQIAQPGAAYFYVELDTGEKLFHRIKKNFPLQFGREVLASEAILNIPEKADWRQCQTSKDEEEALARRFRKDFEPFDFTLDD", "length": 537 }, "evidence": [ { "id": "A0A061IHC6", "url": "https://omabrowser.org/oma/group/A0A061IHC6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "A0A061IHC6", "url": "https://www.uniprot.org/uniprotkb/A0A061IHC6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "post-mRNA release spliceosomal complex", "id": "GO:0071014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071014", "evidence": [ { "database": "UniProtKB", "id": "A0A061IHC6", "url": "https://www.uniprot.org/uniprotkb/A0A061IHC6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA lariat debranching enzyme activator activity", "id": "GO:0061632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061632", "evidence": [ { "database": "UniProtKB", "id": "A0A061IHC6", "url": "https://www.uniprot.org/uniprotkb/A0A061IHC6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 166, "end_pos": 168, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061IHC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IHC6" }, { "id": "PF04677", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04677" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cwf19-like C-terminal", "eco_id": "ECO_0000259", "start_pos": 318, "end_pos": 424, "start_aa": "Arg", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A061IHC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IHC6" }, { "id": "PF04676", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04676" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cwf19-like protein C-terminal", "eco_id": "ECO_0000259", "start_pos": 442, "end_pos": 534, "start_aa": "Gln", "end_aa": "Thr", "glycosite_overlap": "" } 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"tr|A0A061IHK6-1|A0A061IHK6_CRIGR Isoform 1 of Ribosomal biogenesis factor isoform X1 OS=Cricetulus griseus OX=10029 GN=Rbis PE=4 SV=1 CANONICAL=A0A061IHK6-1" }, "locus": {} }, { "isoform_ac": "A0A061IIL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IHK6/entry#A0A061IIL6-1", "sequence": { "sequence": "MAKNKFKGQKSRNVFHIASQKTFKAKNKAKPVTTNLKKINIMNDEKVNRMNTAFVNIQKELANFSKSLSLKSMQKELHHENEPANVDEATRLMAQL", "length": 96, "header": "tr|A0A061IIL6-1|A0A061IIL6_CRIGR Computationally mapped isoform of Ribosomal biogenesis factor isoform X4 OS=Cricetulus griseus OX=10029 GN=Rbis PE=4 SV=1 CANONICAL=A0A061IHK6-1" }, "locus": {} }, { "isoform_ac": "A0A061IKM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IHK6/entry#A0A061IKM9-1", "sequence": { "sequence": "MAKNKFKGQKSRNVFHIASQKTFKAKNKAKPVTTNLKKINIMNDEKVNRMNTAFVNIQKELANFSKSLSLKSMQKELQHHENEPANVDEATRLMAQL", "length": 97, "header": "tr|A0A061IKM9-1|A0A061IKM9_CRIGR Computationally mapped isoform of Ribosomal biogenesis factor isoform X3 OS=Cricetulus griseus OX=10029 GN=Rbis PE=4 SV=1 CANONICAL=A0A061IHK6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K1J5-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IHK6/entry#A0A9J7K1J5-1", "sequence": { "sequence": "MAKNKFKGQKSRNVFHIASQKTFKAKNKAKPVTTNLKKINIMNDEKVNRMNTAFVNIQKELANFSKSLSLKSMQKELIPQQHHENEPANVDEATRLMAQL", "length": 100, "header": "tr|A0A9J7K1J5-1|A0A9J7K1J5_CRIGR Computationally mapped isoform of Ribosomal biogenesis factor isoform X2 OS=Cricetulus griseus OX=10029 GN=Rbis PE=4 SV=1 CANONICAL=A0A061IHK6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"evidence": [ { "database": "UniProtKB", "id": "A0A061IHK6", "url": "https://www.uniprot.org/uniprotkb/A0A061IHK6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 63, "end_pos": 65 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"uniprot_ac": "A0A061IHW2", "uniprot_id": "A0A061IHW2_CRIGR", "mass": { "chemical_mass": 76998.0, "monoisotopic_mass": 76998.0 }, "refseq": { "ac": "XP_003495120", "name": "transcription factor 25 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495120" }, "gene_names": [ { "name": "Tcf25", "type": "recommended", "evidence": [ { "id": "A0A061IHW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IHW2" } ] }, { "name": "Tcf25", "type": "synonym", "evidence": [ { "id": "XP_003495120", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495120" } ] } ], "protein_names": [ { "name": "Transcription factor 25 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A061IHW2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IHW2/entry#names_and_taxonomy" } ] }, { "name": "transcription factor 25 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003495120", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495120" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613583.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003495120", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495120" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IHW2", "url": "https://www.uniprot.org/uniprotkb/A0A061IHW2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tcf25", "url": "https://www.uniprot.org/uniprotkb/A0A061IHW2", "locus": {} } ], "crossref": [ { "id": "100760643", "url": "https://www.ncbi.nlm.nih.gov/gene/100760643", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006994", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006994", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760643", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760643", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IWGKMPP", "url": "https://omabrowser.org/oma/group/IWGKMPP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061IHW2", "url": "https://www.orthodb.org/?gene=A0A061IHW2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2M687", "url": "https://www.orthodb.org/?gene=A0A8C2M687", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FRG2", "url": "https://www.orthodb.org/?gene=A0A9J7FRG2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22684", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22684", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22684:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22684:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04910", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04910", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003495120", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495120", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IHW2", "url": "https://www.uniprot.org/uniprotkb/A0A061IHW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IHW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IHW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M687", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M687", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M687-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M687-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FRG2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FRG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FRG2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRRALRRLRGEQRGQEPLGPDALQFVLLDDDDAEEEGPKQGSGGRRPGGAGKEGVRVNNRFELINIEDLEDDLVVNGERSDCTLPDAVSSGNKGRAQRGKPETKQDEDVAKAGSPEQSNASGKLRKKKKKQKNKKNCTGDSSENGLEDIDRILERIEDSSGFSHPGPPPLNSRKQVLYVEHRHLNPDTELKRYFGARAVLGEQRPRQRQRVYPKCTWLTTPKSTWPRYSKPGLSMRLLESKKGLSFFAFEHSEEYQQAQHKFLVAVESMEPNNIVVLLQTSPYHVDSLLQLSDACRFQEDQEMARDLIERALYSMECAFHPLFSLTSGTCRLDYRRPENRSFYLALYKQMSFLEKRGCPRTALEYCKLILSLEPDEDPLCMLLLIDHLALRARNYEYLIRLFQEWEAHRNLSQLPNFAFSVPLAYFLLSQQTDLPEHELTSARQQASLLIQQALTMFPGALMPLLEYCSVRPDATVSNHRFFGPDAEISQPPALSQLVSLYLGRSHFLWKEPATMSWLEENVREVLQAVDAGDSAVEACENRRKVLYQRAPRNIHRHVILSEIKEAVAALPSDVTTQSVMGFDPLPPLDTIYSYVRPERLSPVSHGNTIALFFRSLLPNYTTEGERLEEGVARGPNRNQGLNRLMLAVRDMMANFHFNDQEVPREDNPEGEGDWD", "length": 676, "header": "tr|A0A061IHW2-1|A0A061IHW2_CRIGR Isoform 1 of Transcription factor 25 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tcf25 PE=4 SV=1 CANONICAL=A0A061IHW2-1" }, "isoforms": [ { "isoform_ac": "A0A061IHW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IHW2/entry#A0A061IHW2-1", "sequence": { "sequence": "MSRRALRRLRGEQRGQEPLGPDALQFVLLDDDDAEEEGPKQGSGGRRPGGAGKEGVRVNNRFELINIEDLEDDLVVNGERSDCTLPDAVSSGNKGRAQRGKPETKQDEDVAKAGSPEQSNASGKLRKKKKKQKNKKNCTGDSSENGLEDIDRILERIEDSSGFSHPGPPPLNSRKQVLYVEHRHLNPDTELKRYFGARAVLGEQRPRQRQRVYPKCTWLTTPKSTWPRYSKPGLSMRLLESKKGLSFFAFEHSEEYQQAQHKFLVAVESMEPNNIVVLLQTSPYHVDSLLQLSDACRFQEDQEMARDLIERALYSMECAFHPLFSLTSGTCRLDYRRPENRSFYLALYKQMSFLEKRGCPRTALEYCKLILSLEPDEDPLCMLLLIDHLALRARNYEYLIRLFQEWEAHRNLSQLPNFAFSVPLAYFLLSQQTDLPEHELTSARQQASLLIQQALTMFPGALMPLLEYCSVRPDATVSNHRFFGPDAEISQPPALSQLVSLYLGRSHFLWKEPATMSWLEENVREVLQAVDAGDSAVEACENRRKVLYQRAPRNIHRHVILSEIKEAVAALPSDVTTQSVMGFDPLPPLDTIYSYVRPERLSPVSHGNTIALFFRSLLPNYTTEGERLEEGVARGPNRNQGLNRLMLAVRDMMANFHFNDQEVPREDNPEGEGDWD", "length": 676, "header": "tr|A0A061IHW2-1|A0A061IHW2_CRIGR Isoform 1 of Transcription factor 25 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tcf25 PE=4 SV=1 CANONICAL=A0A061IHW2-1" }, "locus": {} }, { "isoform_ac": "A0A8C2M687-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IHW2/entry#A0A8C2M687-1", "sequence": { "sequence": "MSRRALRRLRGEQRGQEPLGPDALQFVLLDDDDAEEEGPKQGSGGRRPGGAGKEGVRVNNRFELINIEDLEDDLVVNGERSDCTLPDAVSSGNKGRAQRGKPETKQDEDVAKAGSPEQSNASGKLRKKKKKQKNKKNCTGDSSENGLEDIDRILERIEDSSGFSHPGPPPLNSRKQVLYVEHRHLNPDTELKRYFGARAVLGEQRPRQRQRVYPKCTWLTTPKSTWPRYSKPGLSMRLLESKKGLSFFAFEHSEEYQQAQHKFLVAVESMEPNNIVVLLQTSPYHVDSLLQLSDACRFQEDQEMARDLIERALYSMECAFHPLFSLTSGTCRLDYRRPENRSFYLALYKQMSFLEKRGCPRTALEYCKLILSLEPDEDPLCMLLLIDHLALRARNYEYLIRLFQEWEAHRNLSQLPNFAFSVPLAYFLLSQQTDLPEHELTSARQQASLLIQQALTMFPGALMPLLEYCSVRPDATVSNHRFFGPDAEISQPPALSQLVSLYLGRSHFLWKEPATMSWLEENVREVLQAVDAGDSAVEACENRRKVLYQRAPRNIHRHVILSEIKEAVAALPSDVTTQSVMGFDPLPPLDTIYSYVRPERLSPVSHGNTIALFFRSLLPNYTTEQL", "length": 626, "header": "tr|A0A8C2M687-1|A0A8C2M687_CRIGR Computationally mapped isoform of Transcription factor 25 isoform X2 OS=Cricetulus griseus OX=10029 GN=Tcf25 PE=4 SV=1 CANONICAL=A0A061IHW2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FRG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IHW2/entry#A0A9J7FRG2-1", "sequence": { "sequence": "MSRRALRRLRGEQRGQEPLGPDALQFVLLDDDDAEEEGPKQGSGGRRPGGAGKEGVRVNNRFELINIEDLEDDLVVNGERSDCTLPDAVSSGNKGRAQRGKPETKQDEDVAKAGSPEQSNASGKLRKKKKKQKNKKNCTGDSSENGLEDIDRILERIEDSSGFSHPGPPPLNSRKQVLYVEHRHLNPDTELKRYFGARAVLGEQRPRQRQRVYPKCTWLTTPKSTWPRYSKPGLSMRLLESKKGLSFFAFEHSEEYQQAQHKFLVAVESMEPNNIVVLLQTSPYHVDSLLQLSDACRFQEDQEMARDLIERALYSMECAFHPLFSLTSGTCRLDYRRPENRSFYLALYKQMSFLEKRGCPRTALEYCKLILSLEPDEDPLCMLLLIDHLALRARNYEYLIRLFQEWEAHRNLSQLPNFAFSVPLAYFLLSQQTDLPEHELTSARQQASLLIQQALTMFPGALMPLLEYCSVRPDATVSNHRFFGPDAEISQPPALSQLVSLYLGRSHFLWKEPATMSWLEENVREVLQAVDAGDSAVEACENRRKVLYQRAPRNIHRHVILSEIKEAVAALPSDVTTQSVMGFDPLPPLDTIYSYVRPERLSPVSHGNTIALFFRSLLPNYTTEL", "length": 625, "header": "tr|A0A9J7FRG2-1|A0A9J7FRG2_CRIGR Computationally mapped isoform of Transcription factor 25 isoform X3 OS=Cricetulus griseus OX=10029 GN=Tcf25 PE=4 SV=1 CANONICAL=A0A061IHW2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IHW2", "url": "https://www.uniprot.org/uniprotkb/A0A061IHW2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IHW2", "url": "https://www.uniprot.org/uniprotkb/A0A061IHW2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760643", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760643", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ASZ5-1", "protein_name": "Ribosome quality control complex subunit TCF25", "gene_name": "Tcf25", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRRALRRLRGEQRGQEPLGPDALQFVLLDDDDAEEEGPKTGLGGRRPGGAGKEGVRVNNRFELINIEDLEDDLVVNGERSDCTLPDSASSGNKGRAKHGNPENKQDGDAAAKAGSSEQSNASGKLRKKKKKQKNKKSCTGESSENGLEDIDRILERIEDSSGFSHPGPPPLSSRKHVLYVEHRHLNPDTELKRYFGARAVLGEQRPRQRQRVYPKCTWLTTPKSTWPRYSKPGLSMRLLESKKGLSFFAFEHSEEYQQAQHKFLVAVESMEPNNIVALLQTSPYHVDSLLQLSDACRFQEDQEMARDLIGEPAYPHLLPMEKSWCRRPHWSFYLALYKQMSFLEKRGCPRTALEYCKLILSLEPDEDPLCMLLLIDHMALRARNYEYLIRLFQEWEAHRNLSQLPNFAFSVPLAYFLLSQQTDLPDHELSSARQQASLLIQQALTMFPGVLMPLLEYCSVRPDATVSNHRFFGPDAEISQPPALSQLVSLYLGRSHFLWKEPAIMSWLEENVHEVLEAVDSGDPAVEACENRRKVLYQRAPRNIHRHVILSEIKEAVAALPSDVTTQSVMGFDPLPPVDTIYSYVRPERLSPVSHGNTIALFFRSLLPNYTTEGERLEEGVAGGPNRNQGLNRLMLAVRDMMANFHFNDLEVPREDNPEGEGDWD", "length": 666 }, "evidence": [ { "id": "A0A061IHW2", "url": "https://omabrowser.org/oma/group/A0A061IHW2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MYH7-1", "protein_name": "Transcription factor 25", "gene_name": "TCF25", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRRALRRLRGEQRGQEPLGPGALQFVLHDDDDVEEECPKRGPGGRRPRGAGKEGVRVNNRFELINIEDLDEAPGVNGERTDCLLVDAVVSGNKRRAQSGHSESTRGGNAADTAVPSEQSNTCSKLRKKKRKQKNKKNAGETSQNGLEDIDRILERIEDASGASRPGPPPLSTKKHVLYVEHRHLNPDTELKRYFGARAVLGEQRPRQRQRMYPKCTWLTTPKSTWPRYTKPGLSMRLLESRKGRSVFAFEHSEEYQQTQHKFLAAVESMEPNNIVVLLQSSPYHVDSLLQLSDACRFQEDQETARDLVERALYSMECAFHPLFSLTSGTCRLDYRRPENRSFYLALYKQMSFLEKRGCPRTALEYCKLILSLEPDEDPLCMLLLIDHLALRARSYEYLIRLFEEWEAHRNLSQLPNFAFSVPLAYFLLSQQADLSEQEMSSAREEACVRIQQALTMFPGVLMPLLEYCSVRPDTTVATHHFFGPDAEISQPPALSQLVSLYLGRSHFLWKEPATMSWLEENVHKVLQVVDAGDPAVEACESRRKVLYQRAPRNIHRHVVLSEIKEAVAALPPDVTTQSVLGFDPLPPLDTIYSYVRPERLSPISHGNTIALFFRSLLPNYTVEGERPEDGGPGGLHRDQGLNRLMLAVRDMMANFHFHDLEVLPEEHPEGDGEWD", "length": 676 }, "evidence": [ { "id": "A0A061IHW2", "url": "https://omabrowser.org/oma/group/A0A061IHW2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O80734-1", "protein_name": "Transcription factor-like protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSGRLLKKVLQEHEDSKLQKHHEEEEEEDEEESGARSSINPFDLLNDGDEDPEEIDDETIAEKKNEDADHQSSVADHVQPVSKNKSKKKKKKKNKESGSNVPKAEMTLDETLEALGLNANSKQDKVQETKPNADSSKKASSRFVLEIDSKYLNLENELRRTYGSKAMRSFESESGSQGGSSSRRGGRRGVHHITKTVLVSPKENWSRWDRSFSMEFLETKDGNNYFRYTHSSSYEQAQRAFQAAQAIHDLNGVASVLIHNPYHIESLITMADYFKFVGENDMAADSIGKCLYGLERAWHPMFTPFQGNCRLEFNHDENKLFFKTLFTHMRNMDRRGCHRSALEVCKLLLSLDTSNPVGALFCVDYFALRAEEYAWLEQFSEEYRNDNSLWLFPNFSYSLAIARVYLEKMEPTSSSEATPRDTSKQSSLDLMTQALKLHPTVLNKLVEKVPLKDQAWTKILKHSYFRSDESKIPSLDHLIKIYVERNYLIWRLPDVQKLLRSAADLVIESLEQDGTEAESWLCVRLEAFSSENNQYSHLSTHDFSDSMPTLPPDNLQNFVADPRMVGGEQMAEGGGRGQHQAPPPRPRDLANRSPLAVLIESILPWANFGDGEDEIAHDAHHQPDNNG", "length": 627 }, "evidence": [ { "id": "A0A061IHW2", "url": "https://omabrowser.org/oma/group/A0A061IHW2/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8R3L2-1", "protein_name": "Ribosome quality control complex subunit TCF25", "gene_name": "Tcf25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRRALRRLRGEQRGQEPLGPDALKFVLLDDDDAEEEGPKPGLGGRRPGGAGKEGVRVNNRFELINTEDLEDDLVVNGERSDCTLPDSVSSGNKGRAKHGNAETKQDGGATKAGSSEQSNASGKLRKKKKKQKNKKSCTGESSENGLEDIDRILERIEDSSGFSHPGPPPLSSRKHVLYVEHRHLNPDTELKRYFGARAVLGEQRPRQRQRVYPKCTWLTTPKSTWPRYSKPGLSMRLLESKKGLSFFAFDHNEEYQQAQHKFLVAVESMEPNNIVVLLQTSPYHVDSLLQLSDACRFQEDQEMARDLIERALYSMECAFHPLFSLTSGTCRLDYRRPENRSFYLTLYKQMSFLEKRGCPRTALEYCKLILSLEPDEDPLCMLLLIDHLALRARNYEYLIRLFQEWEAHRNLSQLPNFAFSVPLAYFLLSQQTDLPEHELSSARQQASLLIQQALTMFPGVLMPLLEYCSVRPDATVSNHRFFGPDAEISQPPALGQLVSLYLGRSHFLWKEPAIMSWLEENVHEVLQAVDAGDPAVEACENRRKVLYQRAPRNIHRHVILSEIKEAVAALPSDVTTQSVMGFDPLPPLDTIYSYVRPERLSPVSHGNTIALFFRSLLPNYTTEGERLEEGVAGGPNRNQGLNRLMLAVRDMMANFHFNDLEVPREDNPEGEGDWD", "length": 676 }, "evidence": [ { "id": "A0A061IHW2", "url": "https://omabrowser.org/oma/group/A0A061IHW2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8T2A4-1", "protein_name": "Ribosome quality control complex subunit TCF25", "gene_name": "tcf25", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSTKALKKKQHINVQHVNSSSDEGSEKKVVVVVNSVKPKFSMLNLSDEDDDKSDQDENEDKKDSESEESEEEEEEEEIEKEKPQAKEQLSSKQQKQKQQQQASKKKQAKKKQQQKKKQQQQEKDELELNEIEKSSPPIILSEIEIKDKEFRELFKINTVNLNPDNELKKLFGCKSSDIKGQKKKSVHHFKKKNYIFVQPKPEWPDVMGGFMVMEICNDDKVPSSPTNATTTTTTTTTTTNTVSPKLKSQQQSLDGINYFKIKWGQTYSNIQEEFYLALTTHDPMSLVEIIRYHPYHIDSLLQLGQVCLQTADYSKAGDFVEMAVFAFENVFHHLFNPLNGNCRFEYRHDQNKSCFLAIFRFIQIIGRRACHRTALELCKILLTWDYSDPLYVRLIIDYYSIRSKQYRFLVDLFTKLKTITPTNQGDLSLLPNFCYSAALAMYHLEREKSTTTTSTSTSTSSSKSSSVEESSDILLQKALISFPMVLQPLLEKLKTNFSIPKNGKIITLENDPFFKDDPLEKRIDHLVTLFVERNYQCWQTPEILDWLKSNVIIVLDKVAAKHPMVKQLSDSIKAEYETVNQEVFDHLVLSEYSDVINRLTPDIIEAMHAEGFRDILPQRDPNQAPPQHLRRGGIGQGFQIHQRNQQQQRRVQQQLRQLQQQQQQNLQHQQQQPLEPLLQENPDYTGPANPVLNFLHSLLPWNDPSIQRERQLAATQGTQQPAPGFLDDYVDFSDEDENEN", "length": 740 }, "evidence": [ { "id": "A0A061IHW2", "url": "https://omabrowser.org/oma/group/A0A061IHW2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9BQ70-1", "protein_name": "Ribosome quality control complex subunit TCF25", "gene_name": "TCF25", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRRALRRLRGEQRGQEPLGPGALHFDLRDDDDAEEEGPKRELGVRRPGGAGKEGVRVNNRFELINIDDLEDDPVVNGERSGCALTDAVAPGNKGRGQRGNTESKTDGDDTETVPSEQSHASGKLRKKKKKQKNKKSSTGEASENGLEDIDRILERIEDSTGLNRPGPAPLSSRKHVLYVEHRHLNPDTELKRYFGARAILGEQRPRQRQRVYPKCTWLTTPKSTWPRYSKPGLSMRLLESKKGLSFFAFEHSEEYQQAQHKFLVAVESMEPNNIVVLLQTSPYHVDSLLQLSDACRFQEDQEMARDLVERALYSMECAFHPLFSLTSGACRLDYRRPENRSFYLALYKQMSFLEKRGCPRTALEYCKLILSLEPDEDPLCMLLLIDHLALRARNYEYLIRLFQEWEAHRNLSQLPNFAFSVPLAYFLLSQQTDLPECEQSSARQKASLLIQQALTMFPGVLLPLLESCSVRPDASVSSHRFFGPNAEISQPPALSQLVNLYLGRSHFLWKEPATMSWLEENVHEVLQAVDAGDPAVEACENRRKVLYQRAPRNIHRHVILSEIKEAVAALPPDVTTQSVMGFDPLPPSDTIYSYVRPERLSPISHGNTIALFFRSLLPNYTMEGERPEEGVAGGLNRNQGLNRLMLAVRDMMANFHLNDLEAPHEDDAEGEGEWD", "length": 676 }, "evidence": [ { "id": "A0A061IHW2", "url": "https://omabrowser.org/oma/group/A0A061IHW2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "rescue of stalled ribosome", "id": "GO:0072344", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072344", "evidence": [ { "database": "UniProtKB", "id": "A0A061IHW2", "url": "https://www.uniprot.org/uniprotkb/A0A061IHW2" } ], "pmid": "" }, { "name": "regulation of protein K48-linked ubiquitination", "id": "GO:0061945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061945", "evidence": [ { "database": "UniProtKB", "id": "A0A061IHW2", "url": "https://www.uniprot.org/uniprotkb/A0A061IHW2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A061IHW2", "url": "https://www.uniprot.org/uniprotkb/A0A061IHW2" } ], "pmid": "" }, { "name": "RQC complex", "id": "GO:1990112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990112", "evidence": [ { "database": "UniProtKB", "id": "A0A061IHW2", "url": "https://www.uniprot.org/uniprotkb/A0A061IHW2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 340, "end_pos": 342, "annotation": "n_glycosylation_sequon" }, { "start_pos": 411, "end_pos": 413, "annotation": "n_glycosylation_sequon" }, { "start_pos": 620, "end_pos": 622, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 120, "end_pos": 122 }, { "start_pos": 137, "end_pos": 139 }, { "start_pos": 340, "end_pos": 342 }, { "start_pos": 411, "end_pos": 413 }, { "start_pos": 620, "end_pos": 622 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061IHY9-1", "uniprot_ac": "A0A061IHY9", "uniprot_id": "A0A061IHY9_CRIGR", "mass": { "chemical_mass": 44908.0, "monoisotopic_mass": 44908.0 }, "refseq": { "ac": "XP_016818659", "name": "cotranscriptional regulator FAM172A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016818659" }, "gene_names": [ { "name": "LOC100752273", "type": "recommended", "evidence": [ { "id": "A0A061IHY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IHY9" } ] }, { "name": "LOC100752273", "type": "synonym", "evidence": [ { "id": "XP_016818659", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016818659" } ] } ], "protein_names": [ { "name": "Cotranscriptional regulator FAM172A isoform X4", "type": "synonym", "evidence": [ { "id": "A0A061IHY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IHY9/entry#names_and_taxonomy" } ] }, { "name": "cotranscriptional regulator FAM172A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_016818659", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016818659" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 474 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615976.1) and transcript sequence (IACG01060118.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_016818659.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016818659", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016818659" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IHY9", "url": "https://www.uniprot.org/uniprotkb/A0A061IHY9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100752273", "url": "https://www.uniprot.org/uniprotkb/A0A061IHY9", "locus": {} } ], "crossref": [ { "id": "100752273", "url": "https://www.ncbi.nlm.nih.gov/gene/100752273", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048263", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048263", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053858", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053858", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR21357", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21357", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21357:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21357:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF22749", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22749", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016818659", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016818659", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IHY9", "url": "https://www.uniprot.org/uniprotkb/A0A061IHY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IHY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IHY9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FDQ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FDQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FDQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FFH5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FFH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFH5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FHD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FHD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FHD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FHD4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FHM6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FHM6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FHM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FHM6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GSU8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GSU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GSU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GSU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K5E7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5E7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K5E7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5E7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSISLSSLIFLPIWISTAQIQQGGPDEKEKTTALKDLLSRINLDELMKKDEPPFDFPDTLEGFEYAFNEKGQLRHIKTGEPFVFNYREDLHRWNQKRYEALGEIITKYVYELLEKDCHLQKISIPVDATESEPKSFIFMSEDALTNPQKLMVLIHGSGVVRAGQWARRLIINEDLDSGTQIPFIKRAVDEGYGVIVLNPNENYIEVEKPKMRKQLSADGTDEPAEKRERREKVSKETKKRRDFFEKYRNPQKEKEMMQLFIRENGSPEEHAVYVWDHFIAKSAAESVFFVAHSYGGLAFVELMIQREADVKSKVTAVALTDSVHNVWHQEAGKTIREWMRENCCNWVSSSEPLDTSVESMLPDCPRVSAAADRSRYGSPASMPLLCHRKL", "length": 390, "header": "tr|A0A061IHY9-1|A0A061IHY9_CRIGR Isoform 1 of Cotranscriptional regulator FAM172A isoform X4 OS=Cricetulus griseus OX=10029 GN=LOC100752273 PE=4 SV=1 CANONICAL=A0A061IHY9-1" }, "isoforms": [ { "isoform_ac": "A0A061IHY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IHY9/entry#A0A061IHY9-1", "sequence": { "sequence": "MSISLSSLIFLPIWISTAQIQQGGPDEKEKTTALKDLLSRINLDELMKKDEPPFDFPDTLEGFEYAFNEKGQLRHIKTGEPFVFNYREDLHRWNQKRYEALGEIITKYVYELLEKDCHLQKISIPVDATESEPKSFIFMSEDALTNPQKLMVLIHGSGVVRAGQWARRLIINEDLDSGTQIPFIKRAVDEGYGVIVLNPNENYIEVEKPKMRKQLSADGTDEPAEKRERREKVSKETKKRRDFFEKYRNPQKEKEMMQLFIRENGSPEEHAVYVWDHFIAKSAAESVFFVAHSYGGLAFVELMIQREADVKSKVTAVALTDSVHNVWHQEAGKTIREWMRENCCNWVSSSEPLDTSVESMLPDCPRVSAAADRSRYGSPASMPLLCHRKL", "length": 390, "header": "tr|A0A061IHY9-1|A0A061IHY9_CRIGR Isoform 1 of Cotranscriptional regulator FAM172A isoform X4 OS=Cricetulus griseus OX=10029 GN=LOC100752273 PE=4 SV=1 CANONICAL=A0A061IHY9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FDQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IHY9/entry#A0A9J7FDQ0-1", "sequence": { "sequence": "MSISLSSLIFLPIWISTAQIQQGGPDEKEKTTALKDLLSRINLDELMKKDEPPFDFPDTLEGFEYAFNEKGQLRHIKTGEPFVFNYREDLHRWNQKRYEALGEIITKYVYELLEKDCHLQKISIPEGYGVIVLNPNENYIEVEKPKMRKQLSADGTDEPAEKRERREKVSKETKKRRDFFEKYRNPQKEKEMMQLFIRENGSPEEHAVYVWDHFIAKSAAESVFFVAHSYGGLAFVELMIQREADVKSKVTAVALTDSVHNVWHQEAGKTIREWMRENCCNWVSSSEPLDTSVESMLPDCPRVSAGTDRHELTSWKSFPSIFKFFAEASQAKSSSQKPTLTRRSHRIKHEEL", "length": 352, "header": "tr|A0A9J7FDQ0-1|A0A9J7FDQ0_CRIGR Computationally mapped isoform of Cotranscriptional regulator FAM172A isoform X9 OS=Cricetulus griseus OX=10029 GN=LOC100752273 PE=4 SV=1 CANONICAL=A0A061IHY9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FFH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IHY9/entry#A0A9J7FFH5-1", "sequence": { "sequence": "MKKDEPPFDFPDTLEGFEYAFNEKGQLRHIKTGEPFVFNYREDLHRWNQKRYEALGEIITKYVYELLEKDCHLQKISIPVDATESEPKSFIFMSEDALTNPQKLMVLIHGSGVVRAGQWARRLIINEDLDSGTQIPFIKRAVDEGYGVIVLNPNENYIEVEKPKMRKQLSADGTDEPAEKRERREKVSKETKKRRDFFEKYRNPQKEKEMMQLFIRENGSPEEHAVYVWDHFIAKSAAESVFFVAHSYGGLAFVELMIQREADVKSKVTAVALTDSVHNVWHQEAGKTIREWMRENCCNWVSSSEPLDTSVESMLPDCPRVSAGTDRHELTSWKSFPSIFKFFAEASQAKSSSQKPTLTRRSHRIKHEEL", "length": 370, "header": "tr|A0A9J7FFH5-1|A0A9J7FFH5_CRIGR Computationally mapped isoform of Cotranscriptional regulator FAM172A isoform X8 OS=Cricetulus griseus OX=10029 GN=LOC100752273 PE=4 SV=1 CANONICAL=A0A061IHY9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FHD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IHY9/entry#A0A9J7FHD4-1", "sequence": { "sequence": "MSISLSSLIFLPIWISTAQIQQGGPDEKEKTTALKDLLSRINLDELMKKDEPPFDFPDTLEGFEYAFNEKGQLRHIKTGEPFVFNYREDLHRWNQKRYEALGEIITKYVYELLEKDCHLQKISIPVDATESEPKSFIFMSEDALTNPQKLMVLIHGSGVVRAGQWARRLIINEDLDSGTQIPFIKRAVDEGYGVIVLNPNENYIEVEKPKMRKQLSADGTDEPAEKRERREKVSKETKKRRDFFEKYRNPQKEKEMMQLFIRENGSPEEHAVYVWDHFIAKSAAESVFFVAHSYGGLAFVELMIQREADVKSKVTAVALTDSVHNVWHQEAGKTIREWMRENCCNWVSSSEPLDTSVESMLPDCPRVSAVPGFLAP", "length": 376, "header": "tr|A0A9J7FHD4-1|A0A9J7FHD4_CRIGR Computationally mapped isoform of Cotranscriptional regulator FAM172A isoform X6 OS=Cricetulus griseus OX=10029 GN=LOC100752273 PE=4 SV=1 CANONICAL=A0A061IHY9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FHM6-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IHY9/entry#A0A9J7FHM6-1", "sequence": { "sequence": "MSISLSSLIFLPIWISTAQIQQGGPDEKEKTTALKDLLSRINLDELMKKDEPPFDFPDTLEGFEYAFNEKGQLRHIKTGEPFVFNYREDLHRWNQKRYEALGEIITKYVYELLEKDCHLQKISIPVDATESEPKSFIFMSEDALTNPQKLMVLIHGSGVVRAGQWARRLIINEDLDSGTQIPFIKRAVDEGYGVIVLNPNENYIEVEKPKMRKQLSADGTDEPAEKRERREKVSKETKKRRDFFEKYRNPQKEKEMMQLFIRENGSPEEHAVYVWDHFIAKSAAESVFFVAHSYGGLAFVELMIQREADVKSKVTAVALTDSVHNVWHQEAGKTIREWMRENCCNWVSSSEPLDTSVESMLPDCPRVSAVVRDDEGKPKGRKNKSNPS", "length": 388, "header": "tr|A0A9J7FHM6-1|A0A9J7FHM6_CRIGR Computationally mapped isoform of Cotranscriptional regulator FAM172A isoform X5 OS=Cricetulus griseus OX=10029 GN=LOC100752273 PE=4 SV=1 CANONICAL=A0A061IHY9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GSU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IHY9/entry#A0A9J7GSU8-1", "sequence": { "sequence": "MNHLLISLIHWKDLNMLSMKIITKYVYELLEKDCHLQKISIPVDATESEPKSFIFMSEDALTNPQKLMVLIHGSGVVRAGQWARRLIINEDLDSGTQIPFIKRAVDEGYGVIVLNPNENYIEVEKPKMRKQLSADGTDEPAEKRERREKVSKETKKRRDFFEKYRNPQKEKEMMQLFIRENGSPEEHAVYVWDHFIAKSAAESVFFVAHSYGGLAFVELMIQREADVKSKVTAVALTDSVHNVWHQEAGKTIREWMRENCCNWVSSSEPLDTSVESMLPDCPRVSAGTDRHELTSWKSFPSIFKFFAEASQAKSSSQKPTLTRRSHRIKHEEL", "length": 333, "header": "tr|A0A9J7GSU8-1|A0A9J7GSU8_CRIGR Computationally mapped isoform of Cotranscriptional regulator FAM172A isoform X10 OS=Cricetulus griseus OX=10029 GN=LOC100752273 PE=4 SV=1 CANONICAL=A0A061IHY9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K5E7-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IHY9/entry#A0A9J7K5E7-1", "sequence": { "sequence": "MSISLSSLIFLPIWISTAQIQQGGPDEKEKTTALKDLLSRINLDELMKKDEPPFDFPDTLEGFEYAFNEKGQLRHIKTGEPFVFNYREDLHRWNQKRYEALGEIITKYVYELLEKDCHLQKISIPVDATESEPKSFIFMSEDALTNPQKLMVLIHGSGVVRAGQWARRLIINEDLDSGTQIPFIKRAVDEGYGVIVLNPNENYIEVEKPKMRKQLSADGTDEPAEKRERREKVSKETKKRRDFFEKYRNPQKEKEMMQLFIRMIQREADVKSKVTAVALTDSVHNVWHQEAGKTIREWMRENCCNWVSSSEPLDTSVESMLPDCPRVSAGTDRHELTSWKSFPSIFKFFAEASQAKSSSQKPTLTRRSHRIKHEEL", "length": 376, "header": "tr|A0A9J7K5E7-1|A0A9J7K5E7_CRIGR Computationally mapped isoform of Cotranscriptional regulator FAM172A isoform X7 OS=Cricetulus griseus OX=10029 GN=LOC100752273 PE=4 SV=1 CANONICAL=A0A061IHY9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IHY9", "url": "https://www.uniprot.org/uniprotkb/A0A061IHY9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IHY9", "url": "https://www.uniprot.org/uniprotkb/A0A061IHY9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A061IHY9", "url": "https://www.uniprot.org/uniprotkb/A0A061IHY9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "siRNA binding", "id": "GO:0035197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035197", "evidence": [ { "database": "UniProtKB", "id": "A0A061IHY9", "url": "https://www.uniprot.org/uniprotkb/A0A061IHY9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulatory ncRNA-mediated heterochromatin formation", "id": "GO:0031048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031048", "evidence": [ { "database": "UniProtKB", "id": "A0A061IHY9", "url": "https://www.uniprot.org/uniprotkb/A0A061IHY9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061IHY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IHY9" }, { "id": "PF22749", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22749" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Arb2", "eco_id": "ECO_0000259", "start_pos": 56, "end_pos": 353, "start_aa": "Phe", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 264, "end_pos": 266 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"url": "https://www.uniprot.org/uniprotkb/A0A061II06" } ] }, { "name": "Testin-2", "type": "synonym", "evidence": [ { "id": "XP_027265483", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265483" } ] } ], "protein_names": [ { "name": "Testin-2 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A061II06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061II06/entry#names_and_taxonomy" } ] }, { "name": "testin-2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027265483", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265483" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027265483", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265483" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061II06", "url": "https://www.uniprot.org/uniprotkb/A0A061II06" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Testin-2", "url": "https://www.uniprot.org/uniprotkb/A0A061II06", "locus": {} } ], "crossref": [ { "id": "cd02248", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02248", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100765299", "url": "https://www.ncbi.nlm.nih.gov/gene/100765299", "database": "GeneID", "categories": [ "Genome 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035294871", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294871" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061II50", "url": "https://www.uniprot.org/uniprotkb/A0A061II50" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113834440", "url": "https://www.uniprot.org/uniprotkb/A0A061II50", "locus": {} } ], "crossref": [ { "id": "cd00349", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00349", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "113834440", "url": "https://www.ncbi.nlm.nih.gov/gene/113834440", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020784", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020784", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036769", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036769", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036796", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036796", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113834440", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113834440", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061II50", "url": "https://www.orthodb.org/?gene=A0A061II50", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11661", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11661", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11661:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11661:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00298", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00298", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03946", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03946", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035294871", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294871", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061II50", "url": "https://www.uniprot.org/uniprotkb/A0A061II50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061II50-1", "url": "https://www.uniprot.org/uniprotkb/A0A061II50-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPKFDPNEIKVVYLRCTGGEVGATSTLGPKIGPLGLSPKKVGDDIAKATGEWKGLSITVKLTIQNRQAQIEVVASASAVIIKALKEPPRDRKKQKNIKHSGNITFDEIVGIARQMRHWSLTRELSGTIKEILGTAVCGL", "length": 140, "header": "tr|A0A061II50-1|A0A061II50_CRIGR Isoform 1 of 60S ribosomal protein L12-like OS=Cricetulus griseus OX=10029 GN=LOC113834440 PE=3 SV=1 CANONICAL=A0A061II50-1" }, "isoforms": [ { "isoform_ac": "A0A061II50-1", "url": "https://www.uniprot.org/uniprotkb/A0A061II50/entry#A0A061II50-1", "sequence": { "sequence": "MPPKFDPNEIKVVYLRCTGGEVGATSTLGPKIGPLGLSPKKVGDDIAKATGEWKGLSITVKLTIQNRQAQIEVVASASAVIIKALKEPPRDRKKQKNIKHSGNITFDEIVGIARQMRHWSLTRELSGTIKEILGTAVCGL", "length": 140, "header": "tr|A0A061II50-1|A0A061II50_CRIGR Isoform 1 of 60S ribosomal protein L12-like OS=Cricetulus griseus OX=10029 GN=LOC113834440 PE=3 SV=1 CANONICAL=A0A061II50-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061II50", "url": "https://www.uniprot.org/uniprotkb/A0A061II50" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061II50", "url": "https://www.uniprot.org/uniprotkb/A0A061II50" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:113834440", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113834440", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A061II50", "url": "https://www.uniprot.org/uniprotkb/A0A061II50" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": 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ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027246084", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246084" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IIB3", "url": "https://www.uniprot.org/uniprotkb/A0A061IIB3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Trim35", "url": "https://www.uniprot.org/uniprotkb/A0A061IIB3", "locus": {} } ], "crossref": [ { "id": "cd16599", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16599", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100760599", "url": "https://www.ncbi.nlm.nih.gov/gene/100760599", "database": "GeneID", "categories": [ "Genome 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"categories": [ "Protein" ] }, { "id": "A0A061IIB3", "url": "https://www.uniprot.org/uniprotkb/A0A061IIB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IIB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IIB3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EYZ5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EYZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EYZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EYZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKAASVVTSTAAAAAAAAAAAAAMEPGPSVSPGPSRSFKEELLCAVCYDPFHDAVTLRCGHNFCRRCVTSCWEVQTTPSCPVCKERAVPGELRTNHTLNNLVETLLREEAEGARWTGRRSPRPCRAHRAPLTLFCLEDKELLCCACQADARHQEHRVQPIKDTAQDFRAKCKNMEHVLREKAKAFWALRRTYEAIAKHNEVQTTWLEGRIRYEFDKLRDFLRVEEQATLGAMKEESRKKHLLVEEKMKQLAEQTEALAREIERLQMEIKEDDMTFLMKHKSRKRRLFCTVEPAPLQPGLLMDACKYLDSLQYRVWKKMLGSVESVPFSLDPNTAAGWLKVADDLTSVINHGYRVQVENPERFSSAPCLLGSQVFSKGSHSWEVDVGGLPSWRVGVVRVQAHAQAQAQADVGGEGHSHSCYHDTRSGFWYLCRTQGVDGDHCMTSDTATAPLVQAMPRRLRVELECEEGELSFYDSERHCHLYTFHAHFGEVRPYFYLGSSRGDGPPEPLRICHLRVSIKEELDI", "length": 524, "header": "tr|A0A061IIB3-1|A0A061IIB3_CRIGR Isoform 1 of Tripartite motif-containing protein 35 isoform X3 OS=Cricetulus griseus OX=10029 GN=Trim35 PE=4 SV=1 CANONICAL=A0A061IIB3-1" }, "isoforms": [ { "isoform_ac": "A0A061IIB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IIB3/entry#A0A061IIB3-1", "sequence": { "sequence": 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Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027251226.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027251226", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251226" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IIQ6", "url": "https://www.uniprot.org/uniprotkb/A0A061IIQ6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dennd2d", "url": "https://www.uniprot.org/uniprotkb/A0A061IIQ6", "locus": {} } ], "crossref": [ { "id": "100759018", "url": "https://www.ncbi.nlm.nih.gov/gene/100759018", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001194", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001194", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759018", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759018", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061IIQ6", "url": "https://www.orthodb.org/?gene=A0A061IIQ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15288", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15288", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15288:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15288:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02141", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02141", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03455", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03455", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03456", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03456", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027251226", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027251226", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IIQ6", "url": "https://www.uniprot.org/uniprotkb/A0A061IIQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IIQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IIQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGQGVGRTLRLLRNRLPRLRAGPSQNNTVEAATEPERTQEHSLSSFAGGQHFFEYLLVVSLKRKHSGDDYEPTITYQFPKRENLLRGQQEEEERLLKAIPLFCFPDGNEWTQLTDYSRETFSFVLTNVDGSRKIGYCRRLLPAGPGPRLPKVYCIISCIGCFGLFSKILDEVEKRHQISTAVIYPFMQGLREAAFPAPGKTVTLKSFIPDSGTEFISLTRPLDSHLEHVDFSALLHCLHFEQIIQIFASAVLERKIIFLAEGLSTLSQCIHAAAALLYPFSWAHTYIPVVPESLLATVCCPTPFMVGVQMRFQQEVMESPMEEVLLVNLCEGTFLLSVGDEKDILPPKLQDDILDSLGQGINELKTSEQINEHVSGPFVQFFVKTVGHYASYIKREASGQGHFQERSFCKAVTSKTKRRFVKKFVKTQLFSLFIQEAEKSRNPPAGYFQKKILEYEEQKKQKKSREKTVK", "length": 471, "header": "tr|A0A061IIQ6-1|A0A061IIQ6_CRIGR Isoform 1 of DENN domain-containing protein 2D isoform X2 OS=Cricetulus griseus OX=10029 GN=Dennd2d PE=4 SV=1 CANONICAL=A0A061IIQ6-1" }, "isoforms": [ { "isoform_ac": "A0A061IIQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IIQ6/entry#A0A061IIQ6-1", "sequence": { "sequence": "MEGQGVGRTLRLLRNRLPRLRAGPSQNNTVEAATEPERTQEHSLSSFAGGQHFFEYLLVVSLKRKHSGDDYEPTITYQFPKRENLLRGQQEEEERLLKAIPLFCFPDGNEWTQLTDYSRETFSFVLTNVDGSRKIGYCRRLLPAGPGPRLPKVYCIISCIGCFGLFSKILDEVEKRHQISTAVIYPFMQGLREAAFPAPGKTVTLKSFIPDSGTEFISLTRPLDSHLEHVDFSALLHCLHFEQIIQIFASAVLERKIIFLAEGLSTLSQCIHAAAALLYPFSWAHTYIPVVPESLLATVCCPTPFMVGVQMRFQQEVMESPMEEVLLVNLCEGTFLLSVGDEKDILPPKLQDDILDSLGQGINELKTSEQINEHVSGPFVQFFVKTVGHYASYIKREASGQGHFQERSFCKAVTSKTKRRFVKKFVKTQLFSLFIQEAEKSRNPPAGYFQKKILEYEEQKKQKKSREKTVK", "length": 471, "header": "tr|A0A061IIQ6-1|A0A061IIQ6_CRIGR Isoform 1 of DENN domain-containing protein 2D isoform X2 OS=Cricetulus griseus OX=10029 GN=Dennd2d PE=4 SV=1 CANONICAL=A0A061IIQ6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IIQ6", "url": "https://www.uniprot.org/uniprotkb/A0A061IIQ6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IIQ6", "url": "https://www.uniprot.org/uniprotkb/A0A061IIQ6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759018", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759018", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A061IIQ6", "url": "https://www.uniprot.org/uniprotkb/A0A061IIQ6" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A061IIQ6", "url": "https://www.uniprot.org/uniprotkb/A0A061IIQ6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A061IIQ6", "url": "https://www.uniprot.org/uniprotkb/A0A061IIQ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061IIQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IIQ6" }, { "id": "PS50211", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50211" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UDENN", "eco_id": "ECO_0000259", "start_pos": 55, "end_pos": 445, "start_aa": "Glu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 27, "end_pos": 29 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { 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"url": "https://www.uniprot.org/uniprotkb/A0A061IIU5" } ] }, { "name": "Rnf39", "type": "synonym", "evidence": [ { "id": "XP_027244448", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244448" } ] } ], "protein_names": [ { "name": "RING finger protein 39", "type": "synonym", "evidence": [ { "id": "XP_027244448", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244448" }, { "id": "A0A061IIU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IIU5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027244448", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244448" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IIU5", "url": "https://www.uniprot.org/uniprotkb/A0A061IIU5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rnf39", "url": "https://www.uniprot.org/uniprotkb/A0A061IIU5", "locus": {} } ], "crossref": [ { "id": "cd16592", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16592", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100753435", "url": "https://www.ncbi.nlm.nih.gov/gene/100753435", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050143", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050143", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753435", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753435", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061IIU5", "url": "https://www.orthodb.org/?gene=A0A061IIU5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13445", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13445", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027244448", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244448", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IIU5", "url": "https://www.uniprot.org/uniprotkb/A0A061IIU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IIU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IIU5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAPELGPGLVERLEQLATCPLCGGPFEDPVLLACEHSFCRACLARCWGRPAAPGSEAAPPSCPCCGQPCPRRSLRSNVRLAVEVRISRGLREKLAEPGARTGRRRGGRIPTMGCLDPHGEDMRKTWRRFDVPTPKSSNSGEELPEDYPVVKNMLHRLTADLTLDPRTAHRGLLISSDNRGVSLAPPGTPEPLDSPARFDQLLAVLGAQGFASGRHCWEVETVEGASFRDSASENEDAGESCYAVGAAGESVTRKGLIKLCPSEAVWAVEGRGGRLWALTAPEPTLLGGARPPPQRIRVDLDWERGRVAFYDGRSLDLLFAFQAPRPLGERVFPLLCTCDPRSPLRIVPGEG", "length": 352, "header": "tr|A0A061IIU5-1|A0A061IIU5_CRIGR Isoform 1 of RING finger protein 39 OS=Cricetulus griseus OX=10029 GN=Rnf39 PE=4 SV=1 CANONICAL=A0A061IIU5-1" }, "isoforms": [ { "isoform_ac": "A0A061IIU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IIU5/entry#A0A061IIU5-1", "sequence": { "sequence": "MEAPELGPGLVERLEQLATCPLCGGPFEDPVLLACEHSFCRACLARCWGRPAAPGSEAAPPSCPCCGQPCPRRSLRSNVRLAVEVRISRGLREKLAEPGARTGRRRGGRIPTMGCLDPHGEDMRKTWRRFDVPTPKSSNSGEELPEDYPVVKNMLHRLTADLTLDPRTAHRGLLISSDNRGVSLAPPGTPEPLDSPARFDQLLAVLGAQGFASGRHCWEVETVEGASFRDSASENEDAGESCYAVGAAGESVTRKGLIKLCPSEAVWAVEGRGGRLWALTAPEPTLLGGARPPPQRIRVDLDWERGRVAFYDGRSLDLLFAFQAPRPLGERVFPLLCTCDPRSPLRIVPGEG", "length": 352, "header": "tr|A0A061IIU5-1|A0A061IIU5_CRIGR Isoform 1 of RING finger protein 39 OS=Cricetulus griseus OX=10029 GN=Rnf39 PE=4 SV=1 CANONICAL=A0A061IIU5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613710.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003498988", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498988" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IIZ7", "url": "https://www.uniprot.org/uniprotkb/A0A061IIZ7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Nup43", "url": "https://www.uniprot.org/uniprotkb/A0A061IIZ7", "locus": {} } ], "crossref": [ { "id": "100758256", "url": "https://www.ncbi.nlm.nih.gov/gene/100758256", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758256", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758256", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HDGDVMD", "url": "https://omabrowser.org/oma/group/HDGDVMD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061IIZ7", "url": "https://www.orthodb.org/?gene=A0A061IIZ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22652", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22652", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22652:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22652:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003498988", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498988", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IIZ7", "url": "https://www.uniprot.org/uniprotkb/A0A061IIZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IIZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IIZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEIYAKFVSQKISKTRWRPVPSGSLQTAETFATGSWDNEENCVSLWSIGDFGNLDSDGGFEGDHQLLCDIRHHGDVMDLQFFDQERIVAASSTGCVTVFLHHPNNQTLSVNQQWPAAHHHTGPGSPSYSSAPCTGIVCDNPEIVTVGEDGRINLFRVDHKEAVRTIDNADSSTLHAVTFLRTPEIVTVNSIGQLKIWDFRQQGSEPCQILSLTGDRVPLHCVDRHPNQQHVVATGGQDGMLSIWDVRQGTMPVSLLKAHEAEMWEVHFHPSNPDHLFTCSEDGSLWHWDASTNGPEKSSLFYQGGRSSTFLSHSISNQASVHQSLISSWLSTDPAKDRIEITSLLPSRTLSVNSLDVLGPCLVCGTDAEAIYVTRQLFS", "length": 380, "header": "tr|A0A061IIZ7-1|A0A061IIZ7_CRIGR Isoform 1 of Nucleoporin Nup43 OS=Cricetulus griseus OX=10029 GN=Nup43 PE=4 SV=1 CANONICAL=A0A061IIZ7-1" }, "isoforms": [ { "isoform_ac": "A0A061IIZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IIZ7/entry#A0A061IIZ7-1", "sequence": { "sequence": "MEEIYAKFVSQKISKTRWRPVPSGSLQTAETFATGSWDNEENCVSLWSIGDFGNLDSDGGFEGDHQLLCDIRHHGDVMDLQFFDQERIVAASSTGCVTVFLHHPNNQTLSVNQQWPAAHHHTGPGSPSYSSAPCTGIVCDNPEIVTVGEDGRINLFRVDHKEAVRTIDNADSSTLHAVTFLRTPEIVTVNSIGQLKIWDFRQQGSEPCQILSLTGDRVPLHCVDRHPNQQHVVATGGQDGMLSIWDVRQGTMPVSLLKAHEAEMWEVHFHPSNPDHLFTCSEDGSLWHWDASTNGPEKSSLFYQGGRSSTFLSHSISNQASVHQSLISSWLSTDPAKDRIEITSLLPSRTLSVNSLDVLGPCLVCGTDAEAIYVTRQLFS", "length": 380, "header": "tr|A0A061IIZ7-1|A0A061IIZ7_CRIGR Isoform 1 of Nucleoporin Nup43 OS=Cricetulus griseus OX=10029 GN=Nup43 PE=4 SV=1 CANONICAL=A0A061IIZ7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IIZ7", "url": "https://www.uniprot.org/uniprotkb/A0A061IIZ7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IIZ7", "url": "https://www.uniprot.org/uniprotkb/A0A061IIZ7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758256", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758256", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1VR16-1", "protein_name": "Nucleoporin 43", "gene_name": "NUP43", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEEIYAKFVSQKISKTRWRPLSSGSLQTAETFATGSWDNEENYVSLWSIGDLGNVDSDGGFEGDHQLLCDIRHHGDVMDLQFFDQERIVAASSTGCVTVFLHHPNNQTLSVSQQWTTAHYHAGPGSPSCSSAPCTGVVCNSPEIVTVGEDGRINLFRADYKEAIKTIVWEVHFHPSNPDHLFTCSEDGSLWHWDASTDVPEKSSLFHQGGRSSTFLSHSISNQTNVHQSLISSWLSTDPARDRIEITSLLPSRTLSVNSLDVLGPCLVCGTDAEAIYVTRQLFS", "length": 284 }, "evidence": [ { "id": "A0A061IIZ7", "url": "https://omabrowser.org/oma/group/A0A061IIZ7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E1C370-1", "protein_name": "Nucleoporin 43", "gene_name": "NUP43", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEEVCARFVSQKISKARWRPLPAAALQPPDLFATGSWDNEDNRISIWSVGDVGSAGLNGEYQGEPQLLCDIRHNGDVMDMQFLDQERIVVGSSTGSVTVFRHHQNNQTLSASHRWENAHYHADQYTACGGAACTGVICNNPEIVTVGEDGRINLYRADQKDAVRTIDNADSSTLHAVTFLRTTEILTVNSIGQLKIWDFRQQRNEPAQIFSLTGDRVPLHCVDRHPNQQHIVATGGQDGMLSIWDIRQGTMPVSLLNAHEAEMWEVHFHPSNPDHLFTCSEDGSLWHWDTSTDVSEKPSFLHQGGRSTAYFSHSTINQSVVSAWLSNDPTKDRMEITNLIPNQTLSVNTLDVLGPCLVYGTDAEAIYVNRQLFA", "length": 374 }, "evidence": [ { "id": "A0A061IIZ7", "url": "https://omabrowser.org/oma/group/A0A061IIZ7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P59235-1", "protein_name": "Nucleoporin Nup43", "gene_name": "Nup43", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEEIYAKFVSQKISKTRWRPVPSGSLQTTETFATGSWDNEENCVSLWSIGDFGNLDSDGGFEGDHQLLCDIRHHGDVMDLQFFDQERIVAASSTGCVTVFLHHPNNQTLSVNQQWPAAHYHTGPSSPSYSSAPCTGIVCDNPEIVTVGEDGRINLFRVDHKEAVRTIDNADSSTLHAVTFLRTPEIVTVNSIGQLKIWDFRQQGSEPCQILSLTGDRVPLHCVDRHPDQQHVVATGGQDGMLSIWDVRQGTMPVSLLKAHEAEMWEVHFHPSNPDHLFTCSEDGSLWHWDASTDAPEKSSLFHQGGRSSTFLSHSLSNQAGVHQSLVSSWLSTDPAKDRIEITSLLPSRTLSVNSLDVLGPCLVCGTDAEAIYVTRQLFS", "length": 380 }, "evidence": [ { "id": "A0A061IIZ7", "url": "https://omabrowser.org/oma/group/A0A061IIZ7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54Z22-1", "protein_name": "Nuclear pore complex protein nup43", "gene_name": "nup43", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": 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:: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614628.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003509065", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509065" } ] }, { "annotation": "Putative transporter.", "evidence": [ { "database": "UniProtKB", "id": "A0A061IJ18", "url": "https://www.uniprot.org/uniprotkb/A0A061IJ18#function" }, { "database": "UniProtKB", "id": "ARBA00093767", "url": "https://www.uniprot.org/uniprotkb/ARBA00093767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IJ18", "url": "https://www.uniprot.org/uniprotkb/A0A061IJ18" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Slc35e4", "url": "https://www.uniprot.org/uniprotkb/A0A061IJ18", "locus": {} } ], "crossref": [ { "id": "100757148", "url": "https://www.ncbi.nlm.nih.gov/gene/100757148", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757148", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757148", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MAGLNKW", "url": "https://omabrowser.org/oma/group/MAGLNKW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061IJ18", "url": "https://www.orthodb.org/?gene=A0A061IJ18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11132", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11132", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03151", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03151", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003509065", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509065", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IJ18", "url": "https://www.uniprot.org/uniprotkb/A0A061IJ18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IJ18-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IJ18-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRCPLQRHEGRMTSAEAVAVAGSAREHGRPKWPPDNPEVLGQPARARVVVAALVWLLAGASMSSLNKWIFTVHGFGRPLLLSALHMLAAALACYWGARRPMPRIIQGRVLLLSLTFGTSMACGNVGLSTVPLDLAQLATTTTPLFTLGLSALLLGRRHHPLQFAAMGLLCLGAACSLAGEFRAPPVGCVFLLVATCLRGFKSVQQSALLQEERLDAVTLLYATSLPSFCLLAGAALVMEAGVAPPLAPTDSRLWACVLLSCCLSVVYNLASSSLLALTSALTVHVLGNLTVVGNLILSRLLFGTHLSDLSYVGIALTLSGMFVYHNCEFVASWATRRGLWHRDQPGKDLVECMNHT", "length": 357, "header": "tr|A0A061IJ18-1|A0A061IJ18_CRIGR Isoform 1 of Solute carrier family 35 member E4 OS=Cricetulus griseus OX=10029 GN=Slc35e4 PE=3 SV=1 CANONICAL=A0A061IJ18-1" }, "isoforms": [ { "isoform_ac": "A0A061IJ18-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IJ18/entry#A0A061IJ18-1", "sequence": { "sequence": "MGRCPLQRHEGRMTSAEAVAVAGSAREHGRPKWPPDNPEVLGQPARARVVVAALVWLLAGASMSSLNKWIFTVHGFGRPLLLSALHMLAAALACYWGARRPMPRIIQGRVLLLSLTFGTSMACGNVGLSTVPLDLAQLATTTTPLFTLGLSALLLGRRHHPLQFAAMGLLCLGAACSLAGEFRAPPVGCVFLLVATCLRGFKSVQQSALLQEERLDAVTLLYATSLPSFCLLAGAALVMEAGVAPPLAPTDSRLWACVLLSCCLSVVYNLASSSLLALTSALTVHVLGNLTVVGNLILSRLLFGTHLSDLSYVGIALTLSGMFVYHNCEFVASWATRRGLWHRDQPGKDLVECMNHT", "length": 357, "header": "tr|A0A061IJ18-1|A0A061IJ18_CRIGR Isoform 1 of Solute carrier family 35 member E4 OS=Cricetulus griseus OX=10029 GN=Slc35e4 PE=3 SV=1 CANONICAL=A0A061IJ18-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IJ18", "url": "https://www.uniprot.org/uniprotkb/A0A061IJ18" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IJ18", "url": "https://www.uniprot.org/uniprotkb/A0A061IJ18" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757148", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757148", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0X2P4-1", "protein_name": "Solute carrier family 35 member E4", "gene_name": "SLC35E4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MCPRCPGGDEAAMMAAGGTLRPRRTDPGQPGERPPLRLVLTVAAWLGTGTALAGLNKWIFAAHGFRYPLLLSSLHMLAAVALGYPLGWVRGPPPPVRPRARIYLLSLTFCGSVALGNLGLSLVPLDAAQAVHATAPLATLLLSALLRGRRHHPLQYAAMGPVCAGAACSIAGGVRFHQPGGCVLLAATVLRALKSLQQSLLLQEGRLDAVSLLCLTALPSFCLLFGTAVALEVAPAWQGVLRYDGSLWGCVLLSCLGSVLYNLASFCVLSLTSALTIHLLGNITVVGNLLLSRLLFGSRLSALSYLGIALTLAGMFMYQQPQLIARRWAVWLRHRSPRHQ", "length": 340 }, "evidence": [ { "id": "A0A061IJ18", "url": "https://omabrowser.org/oma/group/A0A061IJ18/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E1BQ38-1", "protein_name": "Solute carrier family 35 member E4", "gene_name": "SLC35E4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MCRCPPDHHDGRMTSAEAVEVAGGARWAGSAEWPPGTPQALRRPGRARVAVAALVWLLAGASMSSLNKWIFTVHGFGRPLLLSALHMLAAALACHRGARRPLPGQTRRQVLLLSLTFGASMACGNVGLSAVPLDLAQLATTTTPLITLALSALLLGRRHHPLQFAAMGPLCLGAACSLAGELRTPPAGCGFLLAATCLRGLKSIQQSALLQEEQLDAVTLLYATSLPSFCLLAGAALVLEAGVAPPPVPTDCHLWACVLLSCLLSVLYNLASFSLLALTSALTVHVLGNLTVVGNLVLSRLLFGSRLSTLSYVGVALTLSGMFLYHNCEFVASWAARRGFRWRDQPGKGL", "length": 350 }, "evidence": [ { "id": "A0A061IJ18", "url": "https://omabrowser.org/oma/group/A0A061IJ18/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RPE3-1", "protein_name": "Solute carrier family 35 member E4", "gene_name": "SLC35E4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MCRCPPEHHDSRMTSAEVVALAGGARLAGSPEWPPDTPQALGRPGRARVAVAALVWLLAGASMSSLNKWIFTVHGFGRPLLLSALHMLAAALACHRGAQRPMPGRTRRQVLLLSLTFGTSMACGNVGLNAVPLDLAQLATTTTPLITLALSGLLLGRRHHPLQFAAMGPLCLGAACSLAGELRTPPAGCGFLLVATCLRGLKSVQQSALLQEERLDAVTLLYATSLPSFCLLVGAALVLEAGVAPPPAPTDSRLWACILLSCLLSVLYNLASFSLLALTSALTVHVLGNLTVVGNLILSRLLFGSRLSTLSYVGIALTLSGMFLYHNCEFVASWAARRGFWRRDQPGKGL", "length": 350 }, "evidence": [ { "id": "A0A061IJ18", "url": "https://omabrowser.org/oma/group/A0A061IJ18/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q54KI9-1", "protein_name": "Sugar phosphate transporter domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSIISNINNIDNNHLAGGALALWFILNISTLILNKYIYSSLYFYYPITLTAIHMFVCWIGSVAVLRVYKLIPLITVQWSGKQFINIMILSILFCSNIVFGNVSLRWVPVSFMQTVKSSVPLFTVILTTLFFSNIGGKKTTFTRGTYLSMIPIVGGVCVASLSEVNFNQAGFIAALASSILSAVFAIVSGLILTQQMNAVNLLYYMSPISCCLLFPLSAFMEWNAIANEWPLYGESKPIVILLLSGLIAFLLNTFTFLVIKLTSPLTYTVSGNLKVVLSISISILVFKNETNFFNVLGCAIAIMGVVCYSNIKYEESKAKLEQQQQQSLKQLESIYEEKLDKESLLSK", "length": 348 }, "evidence": [ { "id": "A0A061IJ18", "url": "https://omabrowser.org/oma/group/A0A061IJ18/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5RKL7-1", "protein_name": "Solute carrier family 35 member E4", "gene_name": "Slc35e4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCRCPLEHHEVRMTSAEAIAVAGSAQEHGRPKWPPDKPQVLGQPALARVVVAALVWLLAGASMSSLNKWIFTVHGFGRPLLLSALHMLAAAVACHWGAQRPVPHSIHRRVLLLSLTFGTSMACGNVGLSTVPLDLAQLATTTTPLFTLALSALLLGRRHHPLQFAAMGPLCLGAACSLAGELRAPPAGCGFLLVATCLRGFKSVQQSALLQEERLDAVTLLYATSLPSFCLLAGAALVLEAGAAPPLPPTDSRLWACVLLSCFLSVVYNLASFSLLALTSALTVHVLGNLTVVGNLILSRLLFGSHLSALSYVGIALTLSGMFLYHNCESVASWATRRGLWNRDQPGKGL", "length": 350 }, "evidence": [ { "id": "A0A061IJ18", "url": "https://omabrowser.org/oma/group/A0A061IJ18/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5XF09-1", "protein_name": "Probable sugar phosphate/phosphate translocator At3g11320", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKIAANGRFFTIGLVASWYSSNIGVLLLNKYLLSNYGFKYPIFLTMCHMTACSLLSYVAIAWMKMVPMQTIRSRVQFLKIAALSLVFCVSVVFGNISLRFLPVSFNQAIGATTPFFTAVFAYLITFKREAWLTYFTLVPVVTGVVIASGSEPSFHLFGFIMCIAATAARALKSVLQGILLSSEGEKLNSMNLLLYMAPIAVVFLLPATLIMEKNVVGITIALARDDFRIVWYLLFNSALAYFVNLTNFLVTKHTSALTLQVLGNAKGAVAVVVSILIFRNPVSVTGMLGYSLTVCGVILYSEAKKRSK", "length": 308 }, "evidence": [ { "id": "A0A061IJ18", "url": "https://omabrowser.org/oma/group/A0A061IJ18/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q6ICL7-1", "protein_name": "Solute carrier family 35 member E4", "gene_name": "SLC35E4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCRCPPEHHDGRMTSAEVGAAAGGAQAAGPPEWPPGSPQALRQPGRARVAMAALVWLLAGASMSSLNKWIFTVHGFGRPLLLSALHMLVAALACHRGARRPMPGGTRCRVLLLSLTFGTSMACGNVGLRAVPLDLAQLVTTTTPLFTLALSALLLGRRHHPLQLAAMGPLCLGAACSLAGEFRTPPTGCGFLLAATCLRGLKSVQQSALLQEERLDAVTLLYATSLPSFCLLAGAALVLEAGVAPPPTAGDSRLWACILLSCLLSVLYNLASFSLLALTSALTVHVLGNLTVVGNLILSRLLFGSRLSALSYVGIALTLSGMFLYHNCEFVASWAARRGLWRRDQPSKGL", "length": 350 }, "evidence": [ { "id": "A0A061IJ18", "url": "https://omabrowser.org/oma/group/A0A061IJ18/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K3D6-1", "protein_name": "Solute carrier family 35 member E4", "gene_name": "Slc35e4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCRCPLEHHEGMMTSAEAVAVAGSAQEHGRPKWPPDKPQVLGQPAPARVVVAALVWLLAGASMSSLNKWIFTVHGFGRPLLLSALHMLAAALACHWGAQRPVPHSIHRRVLLLSLTFGTSMACGNVGLSTVPLDLAQLATTTTPLFTMALSALLLGRRHHPLQFAAMGPLCLGAACSLAGELRAPPAGCGFLLVATCLRGFKSVQQSGALLQEERLDTVTLLYATSLPSFCLLASAALVLEAGTAPPLPPTDSRLWACVLLSCFLSVVYNLASFSLLALTSALTVHVLGNLMVVGNLILSRLLFGSHLSALSYLGITLTLSGMFLYHNCELVASWATRWGLWNRDQPGKGL", "length": 351 }, "evidence": [ { "id": "A0A061IJ18", "url": "https://omabrowser.org/oma/group/A0A061IJ18/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A061IJ18", "url": "https://www.uniprot.org/uniprotkb/A0A061IJ18" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 289, "end_pos": 291, "annotation": "n_glycosylation_sequon" }, { "start_pos": 355, "end_pos": 357, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061IJ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJ18" }, { "id": "PF03151", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03151" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sugar phosphate transporter", "eco_id": "ECO_0000259", "start_pos": 49, "end_pos": 325, "start_aa": "Val", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 289, "end_pos": 291 }, { "start_pos": 355, "end_pos": 357 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061IJH1-1", "uniprot_ac": "A0A061IJH1", "uniprot_id": "A0A061IJH1_CRIGR", "mass": { "chemical_mass": 46457.0, "monoisotopic_mass": 46457.0 }, "refseq": { "ac": "XP_027253932", "name": "arylacetamide deacetylase-like 4 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253932" }, "gene_names": [ { "name": "LOC100759860", "type": "recommended", "evidence": [ { "id": "A0A061IJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJH1" } ] }, { "name": "LOC100759860", "type": "synonym", "evidence": [ { "id": "XP_027253932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253932" } ] } ], "protein_names": [ { "name": "Arylacetamide deacetylase-like 4 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A061IJH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJH1/entry#names_and_taxonomy" } ] }, { "name": "arylacetamide deacetylase-like 4 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027253932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253932" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027253932", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253932" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IJH1", "url": "https://www.uniprot.org/uniprotkb/A0A061IJH1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100759860", "url": "https://www.uniprot.org/uniprotkb/A0A061IJH1", "locus": {} } ], "crossref": [ { "id": "100759860", "url": "https://www.ncbi.nlm.nih.gov/gene/100759860", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013094", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013094", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759860", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759860", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061IJH1", "url": "https://www.orthodb.org/?gene=A0A061IJH1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48081", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48081", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48081:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48081:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07859", "url": 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"sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061IJK2-1", "uniprot_ac": "A0A061IJK2", "uniprot_id": "A0A061IJK2_CRIGR", "mass": { "chemical_mass": 30956.0, "monoisotopic_mass": 30956.0 }, "refseq": { "ac": "XP_027244627", "name": "uncharacterized protein C6orf47 homolog isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244627" }, "gene_names": [ { "name": "CUNH6orf47", "type": "recommended", "evidence": [ { "id": "A0A061IJK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJK2" } ] }, { "name": "CUNH6orf47", "type": "synonym", "evidence": [ { "id": "XP_027244627", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244627" } ] } ], "protein_names": [ { "name": "Uncharacterized protein C6orf47 homolog isoform X2", "type": "synonym", "evidence": [ { "id": "A0A061IJK2", "database": "UniProtKB", "url": 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This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027244627", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244627" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IJK2", "url": "https://www.uniprot.org/uniprotkb/A0A061IJK2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "CUNH6orf47", "url": "https://www.uniprot.org/uniprotkb/A0A061IJK2", "locus": {} } ], "crossref": [ { "id": "100760681", "url": "https://www.ncbi.nlm.nih.gov/gene/100760681", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760681", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760681", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061IJK2", "url": "https://www.orthodb.org/?gene=A0A061IJK2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14307", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14307", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14307:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14307:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15576", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15576", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027244627", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244627", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IJK2", "url": "https://www.uniprot.org/uniprotkb/A0A061IJK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IJK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IJK2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFLRRLGSWLPRPWGRRKSTKAELPAPETRWVDSSPENSGSDWDSAPETMGDAGPPKTKDAGKPRTPGAAPGTNREDQVDHPGGKRKDSFERDKTVSSAQEPSRLETGGPIPKLDSGGAKNHGGPPHGGAGTAGPEAVLEKPGRRQKLLRWLRGGPGEPSNYLRDPEEYLHISTNLTLHLLELLASALLALCSRPLRAVLDALGLRGPVGLWLHGLLCFLAALHGLHAVLSLLTAHTLHFACLFGLLQALVLAVSLQGPSEDEETADWESEGQGQEVREPREGPGRVL", "length": 288, "header": "tr|A0A061IJK2-1|A0A061IJK2_CRIGR Isoform 1 of Uncharacterized protein C6orf47 homolog isoform X2 OS=Cricetulus griseus OX=10029 GN=CUNH6orf47 PE=4 SV=1 CANONICAL=A0A061IJK2-1" }, "isoforms": [ { "isoform_ac": "A0A061IJK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IJK2/entry#A0A061IJK2-1", "sequence": { "sequence": "MFLRRLGSWLPRPWGRRKSTKAELPAPETRWVDSSPENSGSDWDSAPETMGDAGPPKTKDAGKPRTPGAAPGTNREDQVDHPGGKRKDSFERDKTVSSAQEPSRLETGGPIPKLDSGGAKNHGGPPHGGAGTAGPEAVLEKPGRRQKLLRWLRGGPGEPSNYLRDPEEYLHISTNLTLHLLELLASALLALCSRPLRAVLDALGLRGPVGLWLHGLLCFLAALHGLHAVLSLLTAHTLHFACLFGLLQALVLAVSLQGPSEDEETADWESEGQGQEVREPREGPGRVL", "length": 288, "header": "tr|A0A061IJK2-1|A0A061IJK2_CRIGR Isoform 1 of Uncharacterized protein C6orf47 homolog isoform X2 OS=Cricetulus griseus OX=10029 GN=CUNH6orf47 PE=4 SV=1 CANONICAL=A0A061IJK2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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] }, { "id": "A0A061IKW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IKW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J5A5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5A5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J5A5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5A5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J5H7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J5H7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5H7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPEPVEDCVQSTLAALYPPFEATAPTLLGQVFQVVERTYQEDALRYTLDFLVPAKHLLAKVQQEACAQYSGFLFFHEGWPLCLHEQVVVQLAALPWQLLRPGDFYLQVVPSAAQAPRLALKCLAPGGGRVQELPVPSEACAYLFTPEWLQGVNKDRPTGRLSTCLLSAPSGIQRLPWAELICPRFVHKEGLMVGHQPSTLPPELPSGPPGLPSSPLPEEVLGTRSPGDGHNAPAEGPEGEYVELLEVTLPHMRGSPTDAEASGLSRTRTVPTRKSTGGKGRHRRHRAWMHQKGLGSRDQDGSRPPGEGSSTGVSSDSPPGAEADPDTTVLVASEPPAEALGETSESCLLSGEAGGGVGQGTEGPPGTPRRTGKGNRRKKRAASRAAVKGESTPLSPRDKEETRQQEVLVSLPSPSEQEPAECSPVKEEEDSGKPESELKELKPTDEKEPVPPEDCEPPEEGIRESEQKGLIPVSTAGSTGPEWLPSDPPTQPLETVQDVKGDSIPEETPEVSILDHPLVAWDLMASGFFVLTGGIDQTGRALLTITPPPPCLPEEPSPSQETLNTALRYLYSLLRPDLQLLGLTILLDLRKAPPLPPALIPALSQLQDSGNPPLIQRLMILIHEEPPAELCGFQGAELLSEKDLKRVAKPEELPWDLGGHKDVSPNHWVEIHQEVARLCSLCQGVLTSVRQAIEELEGAAEAQEEEAAGMPEPLQKVLADPRLTALQRTGGAILMRLRSTHSSKLEGPGPAVLYQEVDEAIHQLVRLSNLRVQRQEQRQRLHQLQQVLQWLSGPGEEQLASFAMPGNSLSVLQETELRFRAFSTEVQERLVQAREALALEEDMASQKVLDIFEQRLEQVESGLHRALRLQRFFQQAHEWVDEGSARLAGAGPGREAVLAALALRRAPEPSAGTFQEMRALALDLGSPAVLREWGRCRARCQELERRIQQQLGEEASPRGHRRRRADSASSTGAQHGAHSPSPSLSSLLLPSSPGPRAAPSHCSLTPCGEDYEEEGLELAPEADGRPPRAVLIRGLEVTSTEVVDRTCSPREHVLLGRAGGPDGPWGIGTPRMERKRSISAQQRLVSELIACEQEYITTLNEPVPPPGPELTPELRCTWAAALSARERLRSFHGTHFLQELQGCTTHPLRIGACFLRHGDQFNLYAQLVKHRHKLESGLAALTSSAKGSMESSPCLPRALQQPLEQLARYGQFLEELLREAGPELSSERQALRAAVQLLQEQEARGRDLLAVEAVRGCEIDLKEQGQLLHRDPFTVICGRKKCLRHVFLFEDLLLFSKFKGFEGGSETFVYKQAFKTADMGLTENIGDSGLCFELWFRRRRAREAYTLQAISPETKLKWTSSIAQLLWRQAAHNKELRVQQMVSMGIGNKPFLDIKALGERTLSALLTGRAARTRASVAVSSFEHAGPSLPGLSPGACSLPARVEEEAWDLDVKQISLASETLDSSGDVSPGPRNSPSLQPPHHGSSTPTLASGGILGLSRQAWLRSIKVRESFPSPE", "length": 1518, "header": "tr|A0A061IJX5-1|A0A061IJX5_CRIGR Isoform 1 of Rho guanine nucleotide exchange factor 40 isoform X5 OS=Cricetulus griseus OX=10029 GN=Arhgef40 PE=4 SV=1 CANONICAL=A0A061IJX5-1" }, "isoforms": [ { "isoform_ac": "A0A061IJX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IJX5/entry#A0A061IJX5-1", "sequence": { "sequence": "MEPEPVEDCVQSTLAALYPPFEATAPTLLGQVFQVVERTYQEDALRYTLDFLVPAKHLLAKVQQEACAQYSGFLFFHEGWPLCLHEQVVVQLAALPWQLLRPGDFYLQVVPSAAQAPRLALKCLAPGGGRVQELPVPSEACAYLFTPEWLQGVNKDRPTGRLSTCLLSAPSGIQRLPWAELICPRFVHKEGLMVGHQPSTLPPELPSGPPGLPSSPLPEEVLGTRSPGDGHNAPAEGPEGEYVELLEVTLPHMRGSPTDAEASGLSRTRTVPTRKSTGGKGRHRRHRAWMHQKGLGSRDQDGSRPPGEGSSTGVSSDSPPGAEADPDTTVLVASEPPAEALGETSESCLLSGEAGGGVGQGTEGPPGTPRRTGKGNRRKKRAASRAAVKGESTPLSPRDKEETRQQEVLVSLPSPSEQEPAECSPVKEEEDSGKPESELKELKPTDEKEPVPPEDCEPPEEGIRESEQKGLIPVSTAGSTGPEWLPSDPPTQPLETVQDVKGDSIPEETPEVSILDHPLVAWDLMASGFFVLTGGIDQTGRALLTITPPPPCLPEEPSPSQETLNTALRYLYSLLRPDLQLLGLTILLDLRKAPPLPPALIPALSQLQDSGNPPLIQRLMILIHEEPPAELCGFQGAELLSEKDLKRVAKPEELPWDLGGHKDVSPNHWVEIHQEVARLCSLCQGVLTSVRQAIEELEGAAEAQEEEAAGMPEPLQKVLADPRLTALQRTGGAILMRLRSTHSSKLEGPGPAVLYQEVDEAIHQLVRLSNLRVQRQEQRQRLHQLQQVLQWLSGPGEEQLASFAMPGNSLSVLQETELRFRAFSTEVQERLVQAREALALEEDMASQKVLDIFEQRLEQVESGLHRALRLQRFFQQAHEWVDEGSARLAGAGPGREAVLAALALRRAPEPSAGTFQEMRALALDLGSPAVLREWGRCRARCQELERRIQQQLGEEASPRGHRRRRADSASSTGAQHGAHSPSPSLSSLLLPSSPGPRAAPSHCSLTPCGEDYEEEGLELAPEADGRPPRAVLIRGLEVTSTEVVDRTCSPREHVLLGRAGGPDGPWGIGTPRMERKRSISAQQRLVSELIACEQEYITTLNEPVPPPGPELTPELRCTWAAALSARERLRSFHGTHFLQELQGCTTHPLRIGACFLRHGDQFNLYAQLVKHRHKLESGLAALTSSAKGSMESSPCLPRALQQPLEQLARYGQFLEELLREAGPELSSERQALRAAVQLLQEQEARGRDLLAVEAVRGCEIDLKEQGQLLHRDPFTVICGRKKCLRHVFLFEDLLLFSKFKGFEGGSETFVYKQAFKTADMGLTENIGDSGLCFELWFRRRRAREAYTLQAISPETKLKWTSSIAQLLWRQAAHNKELRVQQMVSMGIGNKPFLDIKALGERTLSALLTGRAARTRASVAVSSFEHAGPSLPGLSPGACSLPARVEEEAWDLDVKQISLASETLDSSGDVSPGPRNSPSLQPPHHGSSTPTLASGGILGLSRQAWLRSIKVRESFPSPE", "length": 1518, "header": "tr|A0A061IJX5-1|A0A061IJX5_CRIGR Isoform 1 of Rho guanine nucleotide exchange factor 40 isoform X5 OS=Cricetulus griseus OX=10029 GN=Arhgef40 PE=4 SV=1 CANONICAL=A0A061IJX5-1" }, "locus": {} }, { "isoform_ac": "A0A061IKW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IJX5/entry#A0A061IKW2-1", "sequence": { "sequence": "MEPEPVEDCVQSTLAALYPPFEATAPTLLGQVFQVVERTYQEDALRYTLDFLVPAKHLLAKVQQEACAQYSGFLFFHEGWPLCLHEQVVVQLAALPWQLLRPGDFYLQVVPSAAQAPRLALKCLAPGGGRVQELPVPSEACAYLFTPEWLQGVNKDRPTGRLSTCLLSAPSGIQRLPWAELICPRFVHKEGLMVGHQPSTLPPELPSGPPGLPSSPLPEEVLGTRSPGDGHNAPAEGPEGEYVELLEVTLPHMRGSPTDAEASGLSRTRTVPTRKSTGGKGRHRRHRAWMHQKGLGSRDQDGSRPPGEGSSTGVSSDSPPGAEADPDTTVLVASEPPAEALGETSESCLLSGEAGGGVGQGTEGPPGTPRRTGKGNRRKKRAASRAAVKGESTPLSPRDKEETRQQEVLVSLPSPSEQEPAECSPVKEEEDSGKPESELKELKPTDEKEPVPPEDCEPPEEGIRESEQKGLIPVSTAGSTGPEWLPSDPPTQPLETVQDVKGDSIPEETPEVSILDHPLVAWDLMASGFFVLTGGIDQTGRALLTITPPPPCLPEEPSPSQETLNTALRYLYSLLRPDLQLLGLTILLDLRKAPPLPPALIPALSQLQDSGNPPLIQRLMILIHEEPPAELCGFQGAELLSEKDLKRVAKPEELPWDLGGHKDVSPNHWVEIHQEVARLCSLCQGVLTSVRQAIEELEGAAEAQEEEAAGMPEPLQKVLADPRLTALQRTGGAILMRLRSTHSSKLEGPGPAVLYQEVDEAIHQLVRLSNLRVQRQEQRQRLHQLQQVLQWLSGPGEEQLASFAMPGNSLSVLQETELRFRAFSTEVQERLVQAREALALEEDMASQKVLDIFEQRLEQVESGLHRALRLQRFFQQAHEWVDEGSARLAGAGPGREAVLAALALRRAPEPSAGTFQEMRALALDLGSPAVLREWGRCRARCQELERRIQQQLGEEASPRGHRRRRADSASSTGAQHGAHSPSPSLSSLLLPSSPGPRAAPSHCSLTPCGEDYEEEGLELAPEADGRPPRAVLIRGLEVTSTEVVDRTCSPREHVLLGRAGGPDGPWGIGTPRMERKRSISAQQRLVSELIACEQEYITTLNEPVPPPGPELTPELRCTWAAALSARERLRSFHGTHFLQELQGCTTHPLRIGACFLRHGDQFNLYAQLVKHRHKLESGLAALTSSAKGSMESSPCLPRALQQPLEQLARYGQFLEELLREAGPELSSERQALRAAVQLLQEQEARGRDLLAVEAVRGCEIDLKEQGQLLHRDPFTVICGRKKCLRHVFLFEDLLLFSKFKGFEGGSETFVYKQAFKTADMGLTENIGDSGLCFELWFRRRRAREAYTLQAISPETKLKWTSSIAQLLWRQAAHNKELRVQQMVSMGIGNKPFLDIKALGERTLSALLTGRAARTRASVAVSSFEHAGPSLPGLSPGACSLPARVEEEAWDLDVKQISLASETLDSSGDVSPGPRNSPSLQPPHHGSSTPTLASGGILGLSRQSHSRALSDPTTPL", "length": 1515, "header": "tr|A0A061IKW2-1|A0A061IKW2_CRIGR Computationally mapped isoform of Rho guanine nucleotide exchange factor 40 isoform X6 OS=Cricetulus griseus OX=10029 GN=Arhgef40 PE=4 SV=1 CANONICAL=A0A061IJX5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J5A5-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IJX5/entry#A0A9J7J5A5-1", "sequence": { "sequence": "MEPEPVEDCVQSTLAALYPPFEATAPTLLGQVFQVVERTYQEDALRYTLDFLVPAKHLLAKVQQEACAQYSGFLFFHEGWPLCLHEQVVVQLAALPWQLLRPGDFYLQVVPSAAQAPRLALKCLAPGGGRVQELPVPSEACAYLFTPEWLQGVNKDRPTGRLSTCLLSAPSGIQRLPWAELICPRFVHKEGLMVGHQPSTLPPELPSGPPGLPSSPLPEEVLGTRSPGDGHNAPAEGPEGEYVELLEVTLPHMRGSPTDAEASGLSRTRTVPTRKSTGGKGRHRRHRAWMHQKGLGSRDQDGSRPPGEGSSTGVSSDSPPGAEADPDTTVLVASEPPAEALGETSESCLLSGEAGGGVGQGTEGPPGTPRRTGKGNRRKKRAASRAAVKGESTPLSPRDKEETRQQEVLVSLPSPSEQEPAECSPVKEEEDSGKPESELKELKPTDEKEPVPPEDCEPPEEGIRESEQKGLIPVSTAGSTGPEWLPSDPPTQPLETVQDVKGDSIPEETPEVSILDHPLVAWDLMASGFFVLTGGIDQTGRALLTITPPPPCLPEEPSPSQETLNTALRYLYSLLRPDLQLLGLTILLDLRKAPPLPPALIPALSQLQDSGNPPLIQRLMILIHEEPPAELCGFQGAELLSEKDLKRVAKPEELPWDLGGHKDVSPNHWVEIHQEVARLCSLCQGVLTSVRQAIEELEGAAEAQEEEAAGMPEPLQKVLADPRLTALQRTGGAILMRLRSTHSSKLEGPGPAVLYQEVDEAIHQLVRLSNLRVQRQEQRQRLHQLQQVLQWLSGPGEEQLASFAMPGNSLSVLQETELRFRAFSTEVQERLVQAREALALEEDMASQKVLDIFEQRLEQVESGLHRALRLQRFFQQAHEWVDEGSARLAGAGPGREAVLAALALRRAPEPSAGTFQEMRALALDLGSPAVLREWGRCRARCQELERRIQQQLGEEASPRGHRRRRADSASSTGAQHGAHSPSPSLSSLLLPSSPGPRAAPSHCSLTPCGEDYEEEGLELAPEADGRPPRAVLIRGLEVTSTEVVDRTCSPREHVLLGRAGGPDGPWGIGTPRMERKRSISAQQRLVSELIACEQEYITTLNEPVPPPGPELTPELRCTWAAALSARERLRSFHGTHFLQELQGCTTHPLRIGACFLRHGDQFNLYAQLVKHRHKLESGLAALTSSAKGSMESSPCLPRALQQPLEQLARYGQFLEELLREAGPELSSERQALRAAVQLLQEQEARGRDLLAVEAVRGCEIDLKEQGQLLHRDPFTVICGRKKCLRHVFLFEDLLLFSKFKGFEGGSETFVYKQAFKTADMGLTENIGDSGLCFELWFRRRRAREAYTLQAISPETKLKWTSSIAQLLWRQAAHNKELRVQQMVSMGIGNKPFLDIKALGERTLSALLTGRASETLDSSGDVSPGPRNSPSLQPPHHGSSTPTLASGGILGLSRQAWLRSIKVRESFPSPE", "length": 1470, "header": "tr|A0A9J7J5A5-1|A0A9J7J5A5_CRIGR Computationally mapped isoform of Rho guanine nucleotide exchange factor 40 isoform X7 OS=Cricetulus griseus OX=10029 GN=Arhgef40 PE=4 SV=1 CANONICAL=A0A061IJX5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J5H7-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IJX5/entry#A0A9J7J5H7-1", "sequence": { "sequence": "MEPEPVEDCVQSTLAALYPPFEATAPTLLGQVFQVVERTYQEDALRYTLDFLVPAKHLLAKVQQEACAQYSGFLFFHEGWPLCLHEQVVVQLAALPWQLLRPGDFYLQVVPSAAQAPRLALKCLAPGGGRVQELPVPSEACAYLFTPEWLQGVNKDRPTGRLSTCLLSAPSGIQRLPWAELICPRFVHKEGLMVGHQPSTLPPELPSGPPGLPSSPLPEEVLGTRSPGDGHNAPAEGPEGEYVELLEVTLPHMRGSPTDAEASGLSRTRTVPTRKSTGGKGRHRRHRAWMHQKGLGSRDQDGSRPPGEGSSTGVSSDSPPGAEADPDTTVLVASEPPAEALGETSESCLLSGEAGGGVGQGTEGPPGTPRRTGKGNRRKKRAASRAAVKGESTPLSPRDKEETRQQEVLVSLPSPSEQEPAECSPVKEEEDSGKPESELKELKPTDEKEPVPPEDCEPPEEGIRESEQKGLIPVSTAGSTGPEWLPSDPPTQPLETVQDVKGDSIPEETPEVSILDHPLVAWDLMASGFFVLTGGIDQTGRALLTITPPPPCLPEEPSPSQETLNTALRYLYSLLRPDLQLLGLTILLDLRKAPPLPPALIPALSQLQDSGNPPLIQRLMILIHEEPPAELCGFQGAELLSEKDLKRVAKPEELPWDLGGHKDVSPNHWVEIHQEVARLCSLCQGVLTSVRQAIEELEGAAEAQEEEAAGMPEPLQKVLADPRLTALQRTGGAILMRLRSTHSSKLEGPGPAVLYQEVDEAIHQLVRLSNLRVQRQEQRQRLHQLQQVLQWLSGPGEEQLASFAMPGNSLSVLQETELRFRAFSTEVQERLVQAREALALEEDMASQKVLDIFEQRLEQVESGLHRALRLQRFFQQAHEWVDEGSARLAGAGPGREAVLAALALRRAPEPSAGTFQEMRALALDLGSPAVLREWGRCRARCQELERRIQQQLGEEASPRGHRRRRADSASSTGAQHGAHSPSPSLSSLLLPSSPGPRAAPSHCSLTPCGEDYEEEGLELAPEADGRPPRAVLIRGLEVTSTEVVDRTCSPREHVLLGRAGGPDGPWGIGTPRMERKRSISAQQRLVSELIACEQEYITTLNEPVPPPGPELTPELRCTWAAALSARERLRSFHGTHFLQELQGCTTHPLRIGACFLRHGDQFNLYAQLVKHRHKLESGLAALTSSAKGSMESSPCLPRALQQPLEQLARYGQFLEELLREAGPELSSERQALRAAVQLLQEQEARGRDLLAVEAVRGCEIDLKEQGQLLHRDPFTVICGRKKCLRHVFLFEDLLLFSKFKGFEGGSETFVYKQAFKTADMGLTENIGDSGLCFELWFRRRRAREAYTLQAISPETKLKWTSSIAQLLWRQAAHNKELRVQQMVSMGIGNKPFLDIKALGERTLSALLTGRASETLDSSGDVSPGPRNSPSLQPPHHGSSTPTLASGGILGLSRQSHSRALSDPTTPL", "length": 1467, "header": "tr|A0A9J7J5H7-1|A0A9J7J5H7_CRIGR Computationally mapped isoform of Rho guanine nucleotide exchange factor 40 isoform X8 OS=Cricetulus griseus OX=10029 GN=Arhgef40 PE=4 SV=1 CANONICAL=A0A061IJX5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IJX5", "url": "https://www.uniprot.org/uniprotkb/A0A061IJX5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IJX5", "url": "https://www.uniprot.org/uniprotkb/A0A061IJX5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758097", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758097", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A061IJX5", "url": "https://www.uniprot.org/uniprotkb/A0A061IJX5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061IJX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJX5" }, { "id": "PS50010", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50010" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DH", "eco_id": "ECO_0000259", "start_pos": 1081, "end_pos": 1249, "start_aa": "Ala", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A061IJX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IJX5" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 1261, "end_pos": 1368, "start_aa": "Asp", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IK26", "url": "https://www.uniprot.org/uniprotkb/A0A061IK26" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IK26", "url": "https://www.uniprot.org/uniprotkb/A0A061IK26" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763924", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763924", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1LX06-1", "protein_name": "RIKEN cDNA 1700109H08 gene like", "gene_name": "1700109H08Rikl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEQRALKKLVESFRKTVKCFKKFEVECLIQLFYSLAGCPIGKVDNTKLDCNAFRGVLQNFFGMTNDVLMNRVFFVFDKDGDSHVNLQEWIKGLAVFLRGTFEEKMRFCFEVYYLSGDAYISREKIFDMLKSSLFHNSPEEENEEGIKDLVEISLKKMDYDNDGKISFEDFEKAVRKDGLLLEAFGPCLPDAKTCFHFEALVFKNNSPAS", "length": 209 }, "evidence": [ { "id": "A0A061IK26", "url": "https://omabrowser.org/oma/group/A0A061IK26/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A061IK26", "url": "https://www.uniprot.org/uniprotkb/A0A061IK26" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061IK26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IK26" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 64, "end_pos": 99, "start_aa": "Thr", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 205, "end_pos": 207 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061IK51-1", "uniprot_ac": "A0A061IK51", "uniprot_id": "A0A061IK51_CRIGR", "mass": { "chemical_mass": 97516.0, "monoisotopic_mass": 97516.0 }, "refseq": { "ac": "XP_003508387", "name": "gamma-secretase-activating protein isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508387" }, "gene_names": [ { "name": "Gsap", "type": "recommended", "evidence": [ { "id": "A0A061IK51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IK51" } ] }, { "name": "Gsap", "type": "synonym", "evidence": [ { "id": "XP_003508387", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508387" } ] } ], "protein_names": [ { "name": "Gamma-secretase-activating protein isoform X3", "type": "synonym", "evidence": [ { "id": "A0A061IK51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IK51/entry#names_and_taxonomy" } ] }, { "name": "gamma-secretase-activating protein isoform X3", "type": "synonym", "evidence": [ { "id": "XP_003508387", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508387" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614526.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003508387", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508387" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IK51", "url": "https://www.uniprot.org/uniprotkb/A0A061IK51" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Gsap", "url": "https://www.uniprot.org/uniprotkb/A0A061IK51", "locus": {} } ], "crossref": [ { "id": "cd23105", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23105", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100760803", "url": "https://www.ncbi.nlm.nih.gov/gene/100760803", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026172", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026172", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028010", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028010", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760803", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760803", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061IK51", "url": "https://www.orthodb.org/?gene=A0A061IK51", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7F363", "url": "https://www.orthodb.org/?gene=A0A9J7F363", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7J9Z2", "url": "https://www.orthodb.org/?gene=A0A9J7J9Z2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13630", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13630", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13630:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13630:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14959", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14959", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003508387", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508387", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IK51", "url": "https://www.uniprot.org/uniprotkb/A0A061IK51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IK51-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IK51-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F363", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F363", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F363-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F363-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F777", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F777", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F777-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F777-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J569", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J569", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J569-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J569-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J9Z2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J9Z2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J9Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J9Z2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALRLVAHFDVRADVLPSLVAQAATAAEAGDTGVLETAYESLRVLNIERNGNIIYTYKDNKGNSVFGLYDCQTRQNEHLYTFEKDMQAVSCSVNSERTLLAASFVQYTKEGVRSEFHPGSKCLTLLVEIHPVDSVKVLKAVDSCIWVQFLYPHAESHHLQNHLLLISEEKYIERFNIQITREDGNRAVIRNSSHLPKDRIAEDFAWAQWDMSEQRLYYIELEKSKSVLRCIQFWPDESFTLMFEMPLDISLSGLRFKFVNFGYDYHQDQEKLCNQPSLCVFTNHTGSLCVCYSPKFDSGEEITYSVFYLHKGYRKTFTSAPGSAGSHVTKGITFLNLGYLVAVYFPGHFLHLLNIQHPDLICHSLFLTGNNKMAAVLPPSPLQSLPGSLILDCSSGKVYRATLDQSYLLWFLWNAAHLDCEKMAALHCALSCGQDPGFQEDQIIQWVCEHVSGCHSFDLIQEFLIASSYWSVYPELVDVDMLLPHSSVLTWNEEIPGIMLVTEELPLLLMKVYSLTGYWAKLNSNLEYVKYTKPHLHYHNSVVRREWHNLISEEKTGKRRSTMYVRNILDNAIKVISNMEIRTLEPRLIPLLQEEDRHQRLLIGLMVSELRDHLVRHLQGVEKKKIEQTTLDYISKLLNLIWCMLETIWRKHSVHPWVLHLNNRGSAADFEVFHLMTRILDASNNLCFPLPPGFHSLHMILGVHCLPLYNLLHYIDNGVLLLTETAVTMLMKDLDNSEKNEKLKFSIIVRLPPLIGQKVCRFWDHPMSSNIISRNHVAQLLKNYKKEPRNSMIGKSSFPTEFLPLNYFIETLTGLESSHQALCDFEGQDNVDAEFVEEAALKHTMALLGL", "length": 850, "header": "tr|A0A061IK51-1|A0A061IK51_CRIGR Isoform 1 of Gamma-secretase-activating protein isoform X3 OS=Cricetulus griseus OX=10029 GN=Gsap PE=4 SV=1 CANONICAL=A0A061IK51-1" }, "isoforms": [ { "isoform_ac": "A0A061IK51-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IK51/entry#A0A061IK51-1", "sequence": { "sequence": "MALRLVAHFDVRADVLPSLVAQAATAAEAGDTGVLETAYESLRVLNIERNGNIIYTYKDNKGNSVFGLYDCQTRQNEHLYTFEKDMQAVSCSVNSERTLLAASFVQYTKEGVRSEFHPGSKCLTLLVEIHPVDSVKVLKAVDSCIWVQFLYPHAESHHLQNHLLLISEEKYIERFNIQITREDGNRAVIRNSSHLPKDRIAEDFAWAQWDMSEQRLYYIELEKSKSVLRCIQFWPDESFTLMFEMPLDISLSGLRFKFVNFGYDYHQDQEKLCNQPSLCVFTNHTGSLCVCYSPKFDSGEEITYSVFYLHKGYRKTFTSAPGSAGSHVTKGITFLNLGYLVAVYFPGHFLHLLNIQHPDLICHSLFLTGNNKMAAVLPPSPLQSLPGSLILDCSSGKVYRATLDQSYLLWFLWNAAHLDCEKMAALHCALSCGQDPGFQEDQIIQWVCEHVSGCHSFDLIQEFLIASSYWSVYPELVDVDMLLPHSSVLTWNEEIPGIMLVTEELPLLLMKVYSLTGYWAKLNSNLEYVKYTKPHLHYHNSVVRREWHNLISEEKTGKRRSTMYVRNILDNAIKVISNMEIRTLEPRLIPLLQEEDRHQRLLIGLMVSELRDHLVRHLQGVEKKKIEQTTLDYISKLLNLIWCMLETIWRKHSVHPWVLHLNNRGSAADFEVFHLMTRILDASNNLCFPLPPGFHSLHMILGVHCLPLYNLLHYIDNGVLLLTETAVTMLMKDLDNSEKNEKLKFSIIVRLPPLIGQKVCRFWDHPMSSNIISRNHVAQLLKNYKKEPRNSMIGKSSFPTEFLPLNYFIETLTGLESSHQALCDFEGQDNVDAEFVEEAALKHTMALLGL", "length": 850, "header": "tr|A0A061IK51-1|A0A061IK51_CRIGR Isoform 1 of Gamma-secretase-activating protein isoform X3 OS=Cricetulus griseus OX=10029 GN=Gsap PE=4 SV=1 CANONICAL=A0A061IK51-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F363-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IK51/entry#A0A9J7F363-1", "sequence": { "sequence": "MQVLGTEPVSSARTHLYTFEKDMQAVSCSVNSERTLLAASFVQYTKEGVRSEFHPGSKCLTLLVEIHPVDSVKVLKAVDSCIWVQFLYPHAESHHLQNHLLLISEEKYIERFNIQITREDGNRAVIRNSSHLPKDRIAEDFAWAQWDMSEQRLYYIELEKSKSVLRCIQFWPDESFTLMFEMPLDISLSGLRFKFVNFGYDYHQDQEKLCNQPSLCVFTNHTGSLCVCYSPKFDSGEEITYSVFYLHKGYRKTFTSAPGSAGSHVTKGITFLNLGYLVAVYFPGHFLHLLNIQHPDLICHSLFLTGNNKMAAVLPPSPLQSLPGSLILDCSSGKVYRATLDQSYLLWFLWNAAHLDCEKMAALHCALSCGQDPGFQEDQIIQWVCEHVSGCHSFDLIQEFLIASSYWSVYPELVDVDMLLPHSSVLTWNEEIPGIMLVTEELPLLLMKVYSLTGYWAKLNSNLEYVKYTKPHLHYHNSVVRREWHNLISEEKTGKRRSTMYVRNILDNAIKVISNMEIRTLEPRLIPLLQEEDRHQRLLIGLMVSELRDHLVRHLQGVEKKKIEQTTLDYISKLLNLIWCMLETIWRKHSVHPWVLHLNNRGSAADFEVFHLMTRILDASNNLCFPLPPGFHSLHMILGVHCLPLYNLLHYIDNGVLLLTETAVTMLMKDLDNSEKNEKLKFSIIVRLPPLIGQKVCRFWDHPMSSNIISRNHVAQLLKNYKKEPRNSMIGKSSFPTEFLPLNYFIETLTGLESSHQALCDFEGQDNVDAEFVEEAALKHTMALLGL", "length": 787, "header": "tr|A0A9J7F363-1|A0A9J7F363_CRIGR Computationally mapped isoform of Gamma-secretase-activating protein isoform X5 OS=Cricetulus griseus OX=10029 GN=Gsap PE=4 SV=1 CANONICAL=A0A061IK51-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F777-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IK51/entry#A0A9J7F777-1", "sequence": { "sequence": "MQAVSCSVNSERTLLAASFVQYTKEGVRSEFHPGSKCLTLLVEIHPVDSVKVLKAVDSCIWVQFLYPHAESHHLQNHLLLISEEKYIERFNIQITREDGNRAVIRNSSHLPKDRIAEDFAWAQWDMSEQRLYYIELEKSKSVLRCIQFWPDESFTLMFEMPLDISLSGLRFKFVNFGYDYHQDQEKLCNQPSLCVFTNHTGSLCVCYSPKFDSGEEITYSVFYLHKGYRKTFTSAPGSAGSHVTKGITFLNLGYLVAVYFPGHFLHLLNIQHPDLICHSLFLTGNNKMAAVLPPSPLQSLPGSLILDCSSGKVYRATLDQSYLLWFLWNAAHLDCEKMAALHCALSCGQDPGFQEDQIIQWVCEHVSGCHSFDLIQEFLIASSYWSVYPELVDVDMLLPHSSVLTWNEEIPGIMLVTEELPLLLMKVYSLTGYWAKLNSNLEYVKYTKPHLHYHNSVVRREWHNLISEEKTGKRRSTMYVRNILDNAIKVISNMEIRTLEPRLIPLLQEEDRHQRLLIGLMVSELRDHLVRHLQGVEKKKIEQTTLDYISKLLNLIWCMLETIWRKHSVHPWVLHLNNRGSAADFEVFHLMTRILDASNNLCFPLPPGFHSLHMILGVHCLPLYNLLHYIDNGVLLLTETAVTMLMKDLDNSEKNEKLKFSIIVRLPPLIGQKVCRFWDHPMSSNIISRNHVAQLLKNYKKEPRNSMIGKSSFPTEFLPLNYFIETLTGLESSHQALCDFEGQDNVDAEFVEEAALKHTMALLGL", "length": 765, "header": "tr|A0A9J7F777-1|A0A9J7F777_CRIGR Computationally mapped isoform of Gamma-secretase-activating protein isoform X1 OS=Cricetulus griseus OX=10029 GN=Gsap PE=4 SV=1 CANONICAL=A0A061IK51-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J569-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IK51/entry#A0A9J7J569-1", "sequence": { "sequence": "MQAVSCSVNSERTLLAASFVQYTKEGVRRSKCLTLLVEIHPVDSVKVLKAVDSCIWVQFLYPHAESHHLQNHLLLISEEKYIERFNIQITREDGNRAVIRNSSHLPKDRIAEDFAWAQWDMSEQRLYYIELEKSKSVLRCIQFWPDESFTLMFEMPLDISLSGLRFKFVNFGYDYHQDQEKLCNQPSLCVFTNHTGSLCVCYSPKFDSGEEITYSVFYLHKGYRKTFTSAPGSAGSHVTKGITFLNLGYLVAVYFPGHFLHLLNIQHPDLICHSLFLTGNNKMAAVLPPSPLQSLPGSLILDCSSGKVYRATLDQSYLLWFLWNAAHLDCEKMAALHCALSCGQDPGFQEDQIIQWVCEHVSGCHSFDLIQEFLIASSYWSVYPELVDVDMLLPHSSVLTWNEEIPGIMLVTEELPLLLMKVYSLTGYWAKLNSNLEYVKYTKPHLHYHNSVVRREWHNLISEEKTGKRRSTMYVRNILDNAIKVISNMEIRTLEPRLIPLLQEEDRHQRLLIGLMVSELRDHLVRHLQGVEKKKIEQTTLDYISKLLNLIWCMLETIWRKHSVHPWVLHLNNRGSAADFEVFHLMTRILDASNNLCFPLPPGFHSLHMILGVHCLPLYNLLHYIDNGVLLLTETAVTMLMKDLDNSEKNEKLKFSIIVRLPPLIGQKVCRFWDHPMSSNIISRNHVAQLLKNYKKEPRNSMIGKSSFPTEFLPLNYFIETLTGLESSHQALCDFEGQDNVDAEFVEEAALKHTMALLGL", "length": 760, "header": "tr|A0A9J7J569-1|A0A9J7J569_CRIGR Computationally mapped isoform of Gamma-secretase-activating protein isoform X2 OS=Cricetulus griseus OX=10029 GN=Gsap PE=4 SV=1 CANONICAL=A0A061IK51-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J9Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IK51/entry#A0A9J7J9Z2-1", "sequence": { "sequence": 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This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027254009", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254009" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IK82", "url": "https://www.uniprot.org/uniprotkb/A0A061IK82" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Angptl7", "url": "https://www.uniprot.org/uniprotkb/A0A061IK82", "locus": {} } ], "crossref": [ { "id": "cd00087", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00087", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100755713", "url": "https://www.ncbi.nlm.nih.gov/gene/100755713", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037579", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037579", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755713", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755713", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061IK82", "url": "https://www.orthodb.org/?gene=A0A061IK82", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47221", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47221", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47221:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47221:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00147", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00147", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027254009", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254009", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IK82", "url": "https://www.uniprot.org/uniprotkb/A0A061IK82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IK82-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IK82-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMRKTWLCIILVAFVSHPVWLQKPPKRKTPAQLKAAACCEEMRELKAQVANLSSLLGELSKKQESDWVSVVMQVMELESGSKRMESRLAVAESKYSEMNNQIDIMQLQAAQTVTQTSADAIYDCYSLYQKNYRISGVYKLPPDEFLGSPELEVFCDMETSGGGWTIIQRRKSGLVSFYQDWRQYKQGFGSIRGDFWLGNEHIHRLTRQPTRLRVELEDWEGNARYAEYSHFALANELNSYRLFLGNYSGNVGKDALLYHNNTVFSTKDKDNDNCLDKCAQLRKGGYWYNCCTDSNLNGVYYRQGEHRKHMDGISWYGWHGANYSLKRVEMKIRPEAFQP", "length": 339, "header": "tr|A0A061IK82-1|A0A061IK82_CRIGR Isoform 1 of Angiopoietin-related protein 7 OS=Cricetulus griseus OX=10029 GN=Angptl7 PE=4 SV=1 CANONICAL=A0A061IK82-1" }, "isoforms": [ { "isoform_ac": "A0A061IK82-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IK82/entry#A0A061IK82-1", "sequence": { "sequence": "MMRKTWLCIILVAFVSHPVWLQKPPKRKTPAQLKAAACCEEMRELKAQVANLSSLLGELSKKQESDWVSVVMQVMELESGSKRMESRLAVAESKYSEMNNQIDIMQLQAAQTVTQTSADAIYDCYSLYQKNYRISGVYKLPPDEFLGSPELEVFCDMETSGGGWTIIQRRKSGLVSFYQDWRQYKQGFGSIRGDFWLGNEHIHRLTRQPTRLRVELEDWEGNARYAEYSHFALANELNSYRLFLGNYSGNVGKDALLYHNNTVFSTKDKDNDNCLDKCAQLRKGGYWYNCCTDSNLNGVYYRQGEHRKHMDGISWYGWHGANYSLKRVEMKIRPEAFQP", "length": 339, "header": "tr|A0A061IK82-1|A0A061IK82_CRIGR Isoform 1 of Angiopoietin-related protein 7 OS=Cricetulus griseus OX=10029 GN=Angptl7 PE=4 SV=1 CANONICAL=A0A061IK82-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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"mass": { "chemical_mass": 112673.0, "monoisotopic_mass": 112673.0 }, "refseq": { "ac": "XP_007647437", "name": "testis anion transporter 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007647437" }, "gene_names": [ { "name": "Slc26a8", "type": "recommended", "evidence": [ { "id": "A0A061IL33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IL33" } ] }, { "name": "Slc26a8", "type": "synonym", "evidence": [ { "id": "XP_007647437", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007647437" } ] } ], "protein_names": [ { "name": "Testis anion transporter 1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A061IL33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IL33/entry#names_and_taxonomy" } ] }, { "name": "testis anion transporter 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007647437", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007647437" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 127 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614566.1) and transcript sequence (IACG01107432.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007647437", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007647437" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IL33", "url": "https://www.uniprot.org/uniprotkb/A0A061IL33" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Slc26a8", "url": "https://www.uniprot.org/uniprotkb/A0A061IL33", "locus": {} } ], "crossref": [ { "id": "cd07042", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07042", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100764091", "url": "https://www.ncbi.nlm.nih.gov/gene/100764091", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001902", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001902", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002645", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002645", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011547", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011547", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036513", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036513", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764091", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764091", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MFPILNW", "url": "https://omabrowser.org/oma/group/MFPILNW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061IL33", "url": "https://www.orthodb.org/?gene=A0A061IL33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11814", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11814", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00916", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00916", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01740", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01740", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007647437", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007647437", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IL33", "url": "https://www.uniprot.org/uniprotkb/A0A061IL33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IL33-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IL33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EXC3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EXC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F1T8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1T8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F1T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1T8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQSERSIQNLGSRFRQIPFVYDVKRNVYNEENFQQEHRRKAATSGNVDINVTTFKHHVQCRCSWHKFLRCMLTVFPFLEWMCLYRFKDWLLGDLLAGLSVGLVQVPQGLTLSLLTRQLIPPLNVTYAAFCSSVIYVIFGSCHQMSIGPFFLVSALLINVLKDRPFNNGHLILGTFVKDDFSQPTFYVNYNGSLSVVASMTFLTGVIQLSMGMMGMGFVATYLPEAAISAYLAAVALHIILAQMTCVFGIMISFHAGPISFFYNIINYCIALPKANSTSILLFLTAVVALRINKCIRISFNRYPIEFPMELFLILGFSILTNKISMATESSKMLVNMIPYSFVFPETPDFGILPTIILQAISLSLVSSFLIVSLGKKIANLHNYRINSNQDLIAIGLCNVVSSFFRCCVFTGAMARTIIQDKSGGRQQFASLVGAGVMVLLMVKMGSFFHNMPNAVLAGIVLSNVIPYLQTIYNLPNLWRQDQYDCVVWMVTFSSVIFLGLDVGLLISLAFAFFIITVRSHRTKILVLGQIPNTNIYRNVNDYREVLLIPGVKILQCCNSITFVNVYSLKHKLLKEVSMVKIPLKEEEIFTLFNESYTSLSENKICRCFCDCEELEPETRIVYIERFENKQEHDQSSVNLIRCSYLGNGTMTEESTSEEQVPHTVSSTSQKNLGQSYEDTDKIWLSSNPSRNSSLPPPEGSESLAQSRSRSIIIPYSDTSMAPSIHTIILDFSMVHYVDNEASVVLRQMCNAFYNANILVLISGCHTSVVKSFEKNDFFDEGIRKAQLFLSLHDAVLFALSRKMPEPSELSMDATDTVIQENYSESDKNGNLSNLRHKTGSSIIEAPQRTSQNYINIHKPIKDDLEFDLDLDAMLNSEKNSGLGLNPNLNLDLDQESELEPESELESEIQAKSDLEIDTEFDTDAQTEPETEEEPELVSERERRPQPRTRSHSPWRNYFTAYRFGSSPSQSQVPPHSRSSEKKQTHGHPNSPQFDEDTW", "length": 998, "header": "tr|A0A061IL33-1|A0A061IL33_CRIGR Isoform 1 of Testis anion transporter 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Slc26a8 PE=4 SV=1 CANONICAL=A0A061IL33-1" }, "isoforms": [ { "isoform_ac": "A0A061IL33-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IL33/entry#A0A061IL33-1", "sequence": { "sequence": "MQSERSIQNLGSRFRQIPFVYDVKRNVYNEENFQQEHRRKAATSGNVDINVTTFKHHVQCRCSWHKFLRCMLTVFPFLEWMCLYRFKDWLLGDLLAGLSVGLVQVPQGLTLSLLTRQLIPPLNVTYAAFCSSVIYVIFGSCHQMSIGPFFLVSALLINVLKDRPFNNGHLILGTFVKDDFSQPTFYVNYNGSLSVVASMTFLTGVIQLSMGMMGMGFVATYLPEAAISAYLAAVALHIILAQMTCVFGIMISFHAGPISFFYNIINYCIALPKANSTSILLFLTAVVALRINKCIRISFNRYPIEFPMELFLILGFSILTNKISMATESSKMLVNMIPYSFVFPETPDFGILPTIILQAISLSLVSSFLIVSLGKKIANLHNYRINSNQDLIAIGLCNVVSSFFRCCVFTGAMARTIIQDKSGGRQQFASLVGAGVMVLLMVKMGSFFHNMPNAVLAGIVLSNVIPYLQTIYNLPNLWRQDQYDCVVWMVTFSSVIFLGLDVGLLISLAFAFFIITVRSHRTKILVLGQIPNTNIYRNVNDYREVLLIPGVKILQCCNSITFVNVYSLKHKLLKEVSMVKIPLKEEEIFTLFNESYTSLSENKICRCFCDCEELEPETRIVYIERFENKQEHDQSSVNLIRCSYLGNGTMTEESTSEEQVPHTVSSTSQKNLGQSYEDTDKIWLSSNPSRNSSLPPPEGSESLAQSRSRSIIIPYSDTSMAPSIHTIILDFSMVHYVDNEASVVLRQMCNAFYNANILVLISGCHTSVVKSFEKNDFFDEGIRKAQLFLSLHDAVLFALSRKMPEPSELSMDATDTVIQENYSESDKNGNLSNLRHKTGSSIIEAPQRTSQNYINIHKPIKDDLEFDLDLDAMLNSEKNSGLGLNPNLNLDLDQESELEPESELESEIQAKSDLEIDTEFDTDAQTEPETEEEPELVSERERRPQPRTRSHSPWRNYFTAYRFGSSPSQSQVPPHSRSSEKKQTHGHPNSPQFDEDTW", "length": 998, "header": "tr|A0A061IL33-1|A0A061IL33_CRIGR Isoform 1 of Testis anion transporter 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Slc26a8 PE=4 SV=1 CANONICAL=A0A061IL33-1" }, "locus": {} }, { "isoform_ac": "A0A9J7EXC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IL33/entry#A0A9J7EXC3-1", "sequence": { "sequence": "MQSERSIQNLGSRFRQIPFVYDVKRNVYNEENFQQEHRRKAATSGNVDINVTTFKHHVQCRCSWHKFLRCMLTVFPFLEWMCLYRFKDWLLGDLLAGLSVGLVQVPQGLTLSLLTRQLIPPLNVTYAAFCSSVIYVIFGSCHQMSIGPFFLVSALLINVLKDRPFNNGHLILGTFVKDDFSQPTFYVNYNGSLSVVASMTFLTGVIQLSMGMMGMGFVATYLPEAAISAYLAAVALHIILAQMTCVFGIMISFHAGPISFFYNIINYCIALPKANSTSILLFLTAVVALRINKCIRISFNRYPIEFPMELFLLRVPGDSRLRHSSHYYFTSHIFIFSELLFDRISGQEDCQLAQLQNQFQPGFDSHRPLQRGQLLFQMLCVYRCHGQDYYPRQIWRKTAGAGVMVLLMVKMGSFFHNMPNAVLAGIVLSNVIPYLQTIYNLPNLWRQDQYDCVVWMVTFSSVIFLGLDVGLLISLAFAFFIITVRSHRTKILVLGQIPNTNIYRNVNDYREVLLIPGVKILQCCNSITFVNVYSLKHKLLKEVSMVKIPLKEEEIFTLFNESYTSLSENKICRCFCDCEELEPETRIVYIERFENKQEHDQSSVNLIRCSYLGNGTMTEESTSEEQVPHTVSSTSQKNLGQSYEDTDKIWLSSNPSRNSSLPPPEGSESLAQSRSRSIIIPYSDTSMAPSIHTIILDFSMVHYVDNEASVVLRQMCNAFYNANILVLISGCHTSVVKSFEKNDFFDEGIRKAQLFLSLHDAVLFALSRKMPEPSELSMDATDTVIQENYSESDKNGNLSNLRHKTGSSIIEAPQRTSQNYINIHKPIKDDLEFDLDLDAMLNSEKNSGLGLNPNLNLDLDQESELEPESELESEIQAKSDLEIDTEFDTDAQTEPETEEEPELVSERERRPQPRTRSHSPWRNYFTAYRFGSSPSQSQVPPHSRSSEKKQTHGHPNSPQFDEDTW", "length": 965, "header": "tr|A0A9J7EXC3-1|A0A9J7EXC3_CRIGR Computationally mapped isoform of Testis anion transporter 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Slc26a8 PE=4 SV=1 CANONICAL=A0A061IL33-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F1T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IL33/entry#A0A9J7F1T8-1", "sequence": { "sequence": "MQSERSIQNLGSRFRQIPFVYDVKRNVYNEENFQQEHRRKAATSGNVDINVTTFKHHVQCRCSWHKFLRCMLTVFPFLEWMCLYRFKDWLLGDLLAGLSVGLVQVPQGLTLSLLTRQLIPPLNVTYAAFCSSVIYVIFGSCHQMSIGPFFLVSALLINVLKDRPFNNGHLILGTFVKDDFSQPTFYVNYNGSLSVVASMTFLTGVIQLSMGMMGMGFVATYLPEAAISAYLAAVALHIILAQMTCVFGIMISFHAGPISFFYNIINYCIALPKANSTSILLFLTAVVALRINKCIRISFNRYPIEFPMELFLLRVPGDSRLRHSSHYYFTSHIFIFSELLFDRISGQEDCQLAQLQNQFQPGFDSHRPLQRGQLLFQMLCVYRCHGQDYYPRQIWRKTAGVMVLLMVKMGSFFHNMPNAVLAGIVLSNVIPYLQTIYNLPNLWRQDQYDCVVWMVTFSSVIFLGLDVGLLISLAFAFFIITVRSHRTKILVLGQIPNTNIYRNVNDYREVLLIPGVKILQCCNSITFVNVYSLKHKLLKEVSMVKIPLKEEEIFTLFNESYTSLSENKICRCFCDCEELEPETRIVYIERFENKQEHDQSSVNLIRCSYLGNGTMTEESTSEEQVPHTVSSTSQKNLGQSYEDTDKIWLSSNPSRNSSLPPPEGSESLAQSRSRSIIIPYSDTSMAPSIHTIILDFSMVHYVDNEASVVLRQMCNAFYNANILVLISGCHTSVVKSFEKNDFFDEGIRKAQLFLSLHDAVLFALSRKMPEPSELSMDATDTVIQENYSESDKNGNLSNLRHKTGSSIIEAPQRTSQNYINIHKPIKDDLEFDLDLDAMLNSEKNSGLGLNPNLNLDLDQESELEPESELESEIQAKSDLEIDTEFDTDAQTEPETEEEPELVSERERRPQPRTRSHSPWRNYFTAYRFGSSPSQSQVPPHSRSSEKKQTHGHPNSPQFDEDTW", "length": 963, "header": "tr|A0A9J7F1T8-1|A0A9J7F1T8_CRIGR Computationally mapped isoform of Testis anion transporter 1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Slc26a8 PE=4 SV=1 CANONICAL=A0A061IL33-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IL33", "url": "https://www.uniprot.org/uniprotkb/A0A061IL33" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IL33", "url": "https://www.uniprot.org/uniprotkb/A0A061IL33" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764091", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764091", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0U1RS37-1", "protein_name": "Solute carrier family 26 member 8", "gene_name": "Slc26a8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTERSSQGFGNRYRQIPFMYDVKRSVYNEENFQQEHRRKGPTSGNMDINITTFKHHVQCRCSWHKFLRCMLTVFPFLEWMCLYRFKDWLLGDLLAGLSVGLVQVPQGLTLSLLTRQLIPPLNVAYAAFCSSVIYVIFGSCHQMSIGPFFLVSALMINVLKERPFNNGHLIMGTFVKDDFSVPTFYLNYNRSLSMVASTTFLTGIIQLSMGMLGMGFVATYLPEAATSAYLAAVALHIILAQMTCIFGIMVSFHAGPIAFIYNIINYCIALPKANSTSILLFLTAVVALRVNKCIRISFNRYPIEFPMELLLILGFSMLTSRITMATENSKMLINMIPYSFVFPETPEFGILSRIVLQALSLSVVSSFLLISLGKKIANLHNYRTNSNQDLIAIGLCNLVSSFFRCCVFTGGMARTIIQDKSGGRQQKKLACFSANRRPQLQTGTNACLTRSLQPALSPQFASLVGAGVMLLLMVKIGSFFDNLPNAVLAGIILSNVVPYLETIYNLPTLWRQDQYECVVWMVTFSAAIFLGLDVGLLISLVFTFFVITVRSHRTKILVLGQIPNTNIYRNVNEYREVILIPGVKILQCCSSITFVNVYHLKHKLLKEVNMVKLPLKEEEIYALFHESETSIAENKLCRCFCDCEELEPESRVVYTERYENKQEHGSSINLIRCSYLGSGDSSQTTSEEQVPYTVSSTSQRNIGQNYEDTEKAWLPNSPPRNSSLPPPENSESLAQSRSRSVILPYSDTHTIILDFSMVHYVDNRALVVLRQMCNAFHNADILVLISGCHTSVVKLFEKNDFFDDGITKAQLFLSLHDAVLFALSRKCSEPSDLSVDETETVIQETYSESDKNDNLSNLRFKPGNVIMEGSQHASPNYTKTHRPAKNDLEFDLDPDRLLASDQTSGMDLNLDLDLDLGRESDLDPGSELGSEIQAKPELESELEIDVQTEPETEEESERERKSQPRTRTRAQSPWQSYLTAYRFGSTSSQSAGPPQTPQTRPAEKR", "length": 1006 }, "evidence": [ { "id": "A0A061IL33", "url": "https://omabrowser.org/oma/group/A0A061IL33/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MEY3-1", "protein_name": "Solute carrier family 26 member 8", "gene_name": "SLC26A8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQPDRSFQSFASRYRQSSFTYDVKRDVYNEENFQQEHRKKTASSGNVDIDISTVSHHVQCRCSWHKFRRCLLTVFPFLEWMCFYRFKDWLLGDLLAGISVGLVQIPQVLMLGLLARHLIPPLNVSYAAFCASVIYGIFGSCHQMSIGTFFLVSALAINVLRTQPFNRGHLLLGTFIQADFSNTSFYENYNRSLSSVASVTLLTGIIQLSMGMLGFGFIVAYIPEAAISAYLAATALHVMLSQLTCIFGIMISYNSGPIAFFYNIINYCLGLPKANSTSILLFLTAMVALRINKCIRISFNQYPIEFPMEVFLVLGFAAFSNKVNMATENSLMLMEMIPYSFLFPVTPDMSNLTEVLIESFSLALVSSSLLVFLGKKIASFHNYDVNSNQDLIAIGLCNVVSSFFRSYVFTGAVARTIIQDKTGGRQQFASLVGAGIMLLLMMKMARFFYRLPNAIVAGIILSNVLPYLEAVYTLPSLWRQNQYDCLIWMVTFMSAILLGLDIGLVVAVTFAFFIITVQSHRTKILLLGQIPNTNIYRSFQDYREVANIPGVKIFQCCNAITFVNVHYLKRKVLEEIEMVKMPLTEEEIYTLFSQNEEGAQRGKICRCYCNCDEPEPSPRVIYTERYEVQRGRESSFINLVRCSRFESMNTAQTMSEDQVPYITSSSSQRNPNYEEVEKVWLSDDPSRSMTITLPEASDTQVRATKLLPYSTSTILPSIHTIILDFSMVHLVDARALVVLRQMFSAFQNANILVLIAGCHSFVVRSLEKNDFFDAGITKAQLFLTLHDAVLFALSRKLPESSELSVDESETVIQETFSETDKKEESRHKTNRSLIEAPRSKSPGFSLLPDPEMEEESDLDLYSTIQMSKDHGLDLDLDLDREVEPESELEPESELDQETELEPEPEASPKPNRQKYWSLFRAIIPRSPTQTQARTQSVDRRHQNVKPYTSKADTSEDALEI", "length": 960 }, "evidence": [ { "id": "A0A061IL33", "url": "https://omabrowser.org/oma/group/A0A061IL33/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8R0C3-1", "protein_name": "Testis anion transporter 1", "gene_name": "Slc26a8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQTERSLQSFSNRYTQIPFVYDVKRSVYNEENFQQEHRKKGPTSGNVDIDITTFKHHVQCGCSWHKFLRCMLTVFPFLEWICLYRFKDWLLGDLLAGLSVGLVQVPQGLILSLLTRQLIPPLNVTYAAFCSSVIYVIFGSCHQMSIGPFFLVSALMINVLKDRPFNNGHLILGTFVKDDFSVPTFYLSYNRSLSMVASTTFLTGIIQLSMGMLGMGFMATYLPEAATSAYLAAVALHIILAQMTCILGIMVSFHAGPISFIYNIINYCIALPKANSTSILLFITSVVALRINKCIRITFNRYPIEFPMELLLILGFSLLTSKITMATENSKMLMNMIPYSFVFPENPEFGILSRVVLQALSLSFVSSFLLISLGKKIANFHNYRTNSNQDLIAIGLCNLLSSFFKCCVFTGSLSRTTIQDKSGGRQQFASLVGAGVMLLLMVKMESFFHNLPNAVLAGIILSNVVPYLEAIYNLPSLWRQDQYECIIWMVTFSSAILLGLDVGLLISLAFTFFVITIRSHRTKILVLGQIPNTNIYRNVNDYREVILIPGVKIFQCCSSITFVNVYHLKQKVLKEVNMVKLPLKEEEIYTLFHESETSIAENKLCRCFCDCEELEPEIRVVYTERYENRQEQDSSINLIRCSYLGSGDSSQVTSEEQIPYTVSSTSQRNIVQSYEDTEKAWLPNSPPRNSPLPPPEASESLAQSRSRSIIMPYSDTSVQNNTHTIILDFSMVHYVDNRALVILRQMCNAFYNANILVLISGCHTSVVKSFEKNDFFDEGITKAQLFLSLHDAVLFALSRKFSEPSDLSMDETETVIQETYSESDKNGNLSNLRLKTGKAIIEGSQHASPGFTKNLKPGKDDLEFDLELDPMLSFEQSSGMDLNLDLDLDLDQSELDPGSELDSEIQAKPELELESELETDAQTEPETEEEPELEPEPEPEPETEPEPEPERERKTRTRSQSPWRNYFTAYRFGSSNSQSRAPPQTRPEKRKPHNYPNSP", "length": 999 }, "evidence": [ { "id": "A0A061IL33", "url": "https://omabrowser.org/oma/group/A0A061IL33/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96RN1-1", "protein_name": "Testis anion transporter 1", "gene_name": "SLC26A8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061IL39-1", "uniprot_ac": "A0A061IL39", "uniprot_id": "A0A061IL39_CRIGR", "mass": { "chemical_mass": 20215.0, "monoisotopic_mass": 20215.0 }, "refseq": { "ac": "XP_027240955", "name": "exocyst complex component 1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240955" }, "gene_names": [ { "name": "Exoc1l", "type": "recommended", "evidence": [ { "id": "A0A061IL39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IL39" } ] }, { "name": "Exoc1l", "type": "synonym", "evidence": [ { "id": "XP_027240955", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240955" } ] } ], "protein_names": [ { "name": "Exocyst complex component 1-like", "type": "recommended", "evidence": [ { "id": "A0A061IL39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IL39/entry#names_and_taxonomy" } ] }, { "name": "exocyst complex component 1-like", "type": "synonym", "evidence": [ { "id": "XP_027240955", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240955" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616041.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027240955", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240955" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IL39", "url": "https://www.uniprot.org/uniprotkb/A0A061IL39" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Exoc1l", "url": "https://www.uniprot.org/uniprotkb/A0A061IL39", "locus": {} } ], "crossref": [ { "id": "113831273", "url": "https://www.ncbi.nlm.nih.gov/gene/113831273", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028258", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028258", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113831273", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113831273", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EVEICMV", "url": "https://omabrowser.org/oma/group/EVEICMV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061IL39", "url": "https://www.orthodb.org/?gene=A0A061IL39", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF15277", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15277", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027240955", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027240955", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IL39", "url": "https://www.uniprot.org/uniprotkb/A0A061IL39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IL39-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IL39-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSLVKEDLEKKLFKPLAQNLCEFIEIEFSVQDRYYLCVSVTKTDEVKIIMVKHYRVGLDEKYEVTKKWSLDDLQMIDGKEADTDNPFFDLHFKKVYSLEAYSCASKYSFARTVNRLNHVYLKKDLHIVNFDSTYINDDSIWSSNNKDCLVLMRICFYAFNLVCLSLCPLPL", "length": 172, "header": "tr|A0A061IL39-1|A0A061IL39_CRIGR Isoform 1 of Exocyst complex component 1-like OS=Cricetulus griseus OX=10029 GN=Exoc1l PE=4 SV=1 CANONICAL=A0A061IL39-1" }, "isoforms": [ { "isoform_ac": "A0A061IL39-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IL39/entry#A0A061IL39-1", "sequence": { "sequence": "MSSLVKEDLEKKLFKPLAQNLCEFIEIEFSVQDRYYLCVSVTKTDEVKIIMVKHYRVGLDEKYEVTKKWSLDDLQMIDGKEADTDNPFFDLHFKKVYSLEAYSCASKYSFARTVNRLNHVYLKKDLHIVNFDSTYINDDSIWSSNNKDCLVLMRICFYAFNLVCLSLCPLPL", "length": 172, "header": "tr|A0A061IL39-1|A0A061IL39_CRIGR Isoform 1 of Exocyst complex component 1-like OS=Cricetulus griseus OX=10029 GN=Exoc1l PE=4 SV=1 CANONICAL=A0A061IL39-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IL39", "url": "https://www.uniprot.org/uniprotkb/A0A061IL39" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IL39", "url": "https://www.uniprot.org/uniprotkb/A0A061IL39" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:113831273", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113831273", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1B0GW35-1", "protein_name": "Exocyst complex component 1-like", "gene_name": "EXOC1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSLVKEDLEKKLFKPLSQNLYEFIEIEFSVQDRYYLCVSVTKKEEVKIVMVKHYRIGLDEKYEVTKKWSLNDLQMIDGKEADTDNPFFDLHFKKVYSLEAYSCASKYAFARTVNKLNHAYLKKDLQIVNFDSTYINDDSIWSSNNKDCLVLMRICFYAFNLVCLSLCPLPL", "length": 172 }, "evidence": [ { "id": "A0A061IL39", "url": "https://omabrowser.org/oma/group/A0A061IL39/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "B8A5K8-1", "protein_name": "Exocyst complex component 1-like", "gene_name": "exoc1l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSLLREEMDRVLFRPEGQTLKEFIEIEEQQQGRHFLCVSISKDKEAQISVVMCRRVKHSRTKKLQHSGLEDSYERTETWALTDLLILDGRDPDTDDPCFLMHFNSVRPIRAVSCAAKYTLARCLLSLSRKYHHTALKLKNFDWTYIQPTAMYSDRGDCVVLTQVCFYAFNLVCLSMCPVPLA", "length": 183 }, "evidence": [ { "id": "A0A061IL39", "url": "https://omabrowser.org/oma/group/A0A061IL39/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B9EK06-1", "protein_name": "Exocyst complex component 1-like", "gene_name": "Exoc1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLVKEDLEKKLFKPLAQNLCEFIEIEVSVQDRYFLCVSVTKTDEVKITMVKHYRVGLDEKYEVTKRWSLSDLRMIDGKEADTDNPFFDLHFKKVYSLEAYSCASKYSFARTVSRLNHVYLKKDLHMVNFDSTYINDDSIWSSNNKDCLVLMRICFYAFNLVCLSLCPLPL", "length": 172 }, "evidence": [ { "id": 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"MSSLVKEDLEKRLFKPLAQNLCEFIEIEVSVQDRYYLCVSVTKTDEVKISMVKHYRVGLDEKYEVTKRWSLNDLRMIDGKEADTDNPFFDLHFKKVYSLEAYSCASKYSFARTVSRLNHVYLKKDLHIVNFDSTYINDDSIWSSNNKDCLVLMRICFYAFNLVCLSLCPLPL", "length": 172 }, "evidence": [ { "id": "A0A061IL39", "url": "https://omabrowser.org/oma/group/A0A061IL39/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "R4GKM0-1", "protein_name": "Exocyst complex component 1-like", "gene_name": "LOC107053246", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSSLVKEDLAKRLFGPRRLRLHEFIEVEGSGAERCYLCAAVTKSEEVEICMVKHFRDREEKYEVVEKWFLKDLEMIDGKEADTDNPYFDMHFHKVYSMEAYSCASKYTFARTLSNLNEMYLKKDLKIVNFDSTYLNDDSIWSSNNRDCLVLMRICFYASNLLCLSLCPLS", "length": 170 }, "evidence": [ { "id": "A0A061IL39", "url": "https://omabrowser.org/oma/group/A0A061IL39/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], 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"count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061ILB3-1", "uniprot_ac": "A0A061ILB3", "uniprot_id": "A0A061ILB3_CRIGR", "mass": { "chemical_mass": 12618.0, "monoisotopic_mass": 12618.0 }, "refseq": { "ac": "XP_035294668", "name": "60S ribosomal protein L29-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294668" }, "gene_names": [ { "name": "LOC113834193", "type": "recommended", "evidence": [ { "id": "A0A061ILB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061ILB3" } ] }, { "name": "LOC113834193", "type": "synonym", "evidence": [ { "id": "XP_035294668", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294668" } ] } ], "protein_names": [ { "name": "60S ribosomal protein 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This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035294668", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294668" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061ILB3", "url": "https://www.uniprot.org/uniprotkb/A0A061ILB3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113834193", "url": "https://www.uniprot.org/uniprotkb/A0A061ILB3", "locus": {} } ], "crossref": [ { "id": "113834193", "url": "https://www.ncbi.nlm.nih.gov/gene/113834193", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "cge:113834193", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113834193", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_035294668", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294668", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061ILB3", "url": "https://www.uniprot.org/uniprotkb/A0A061ILB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061ILB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A061ILB3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVDPKFLRKMWLVKKHSKKHLKKMRSHNVKAMSACSEAIEDFQSQRWLSPGCHKAPAAISVTWLPSLTPIGKWIRNYMAKFQTKEVATALPQAQASAPAQAPKGPQAPAKDP", "length": 113, "header": "tr|A0A061ILB3-1|A0A061ILB3_CRIGR Isoform 1 of 60S ribosomal protein L29-like OS=Cricetulus griseus OX=10029 GN=LOC113834193 PE=4 SV=1 CANONICAL=A0A061ILB3-1" }, "isoforms": [ { "isoform_ac": "A0A061ILB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A061ILB3/entry#A0A061ILB3-1", "sequence": { "sequence": "MEVDPKFLRKMWLVKKHSKKHLKKMRSHNVKAMSACSEAIEDFQSQRWLSPGCHKAPAAISVTWLPSLTPIGKWIRNYMAKFQTKEVATALPQAQASAPAQAPKGPQAPAKDP", "length": 113, "header": "tr|A0A061ILB3-1|A0A061ILB3_CRIGR Isoform 1 of 60S ribosomal protein L29-like OS=Cricetulus griseus OX=10029 GN=LOC113834193 PE=4 SV=1 CANONICAL=A0A061ILB3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NW_003615077.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003511366", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511366" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061ILV0", "url": "https://www.uniprot.org/uniprotkb/A0A061ILV0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "CUNH2orf74", "url": "https://www.uniprot.org/uniprotkb/A0A061ILV0", "locus": {} } ], "crossref": [ { "id": "100755791", "url": "https://www.ncbi.nlm.nih.gov/gene/100755791", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027813", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027813", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755791", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755791", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TEKGPCT", "url": "https://omabrowser.org/oma/group/TEKGPCT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061ILV0", "url": "https://www.orthodb.org/?gene=A0A061ILV0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR37882", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37882", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15484", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15484", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003511366", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511366", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061ILV0", "url": "https://www.uniprot.org/uniprotkb/A0A061ILV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061ILV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A061ILV0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFGQNGVDKMDENSKSNPMFFETTTITFFVILLICIICILLLLAIFFYKCFTGKTTEEPAKPPCTDENEGEDCLFASAKMNKPKDQEKVLLRLVNMDMPVRPGILVQRQSKDGEVASPLGEITEAEEDKHRQTLEPLTNAGETTLEGESAEKTPVHVHRTSTAESQKRPLKGVTFSKEVIVVDLGNKYPTPRSYSREHKERK", "length": 202, "header": "tr|A0A061ILV0-1|A0A061ILV0_CRIGR Isoform 1 of Uncharacterized protein C2orf74 homolog OS=Cricetulus griseus OX=10029 GN=CUNH2orf74 PE=4 SV=1 CANONICAL=A0A061ILV0-1" }, "isoforms": [ { "isoform_ac": "A0A061ILV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A061ILV0/entry#A0A061ILV0-1", "sequence": { "sequence": "MFGQNGVDKMDENSKSNPMFFETTTITFFVILLICIICILLLLAIFFYKCFTGKTTEEPAKPPCTDENEGEDCLFASAKMNKPKDQEKVLLRLVNMDMPVRPGILVQRQSKDGEVASPLGEITEAEEDKHRQTLEPLTNAGETTLEGESAEKTPVHVHRTSTAESQKRPLKGVTFSKEVIVVDLGNKYPTPRSYSREHKERK", "length": 202, "header": "tr|A0A061ILV0-1|A0A061ILV0_CRIGR Isoform 1 of Uncharacterized protein C2orf74 homolog OS=Cricetulus griseus OX=10029 GN=CUNH2orf74 PE=4 SV=1 CANONICAL=A0A061ILV0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061ILV0", "url": "https://www.uniprot.org/uniprotkb/A0A061ILV0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061ILV0", "url": "https://www.uniprot.org/uniprotkb/A0A061ILV0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755791", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755791", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A8MZ97-1", "protein_name": "Uncharacterized protein C2orf74", "gene_name": "C2orf74", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSFETTAITFFIILLICLICILLLLVVFLYKCFQGRKGKETKKVPCTDANGGVDCAAAKVVTSNPEDHERILMQVMNLNVPMRPGILVQRQSKEVLATPLENRRDMEAEEENQINEKQEPENAGETGQEEDDGLQKIHTSVTRTPSVVESQKRPLKGVTFSREVIVVDLGNEYPTPRSYTREHKERK", "length": 187 }, "evidence": [ { "id": "A0A061ILV0", "url": "https://omabrowser.org/oma/group/A0A061ILV0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3ZLU7-1", "protein_name": "Similar to human chromosome 2 open reading frame 74", "gene_name": "C14h2orf74", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFAQSKSEKTEDILTLSTVAFETKAITFFIILLICFFCILLLLAMFLYKCYRSQSFEEAMRPLCTGENDDENCLAVNTQMSRPEVNDKVLLHFVNMNMPVRPGILVQRQNKKEMATSLGDIKTEEYRNRQTYEPAISRETKHEGEFAEKIPIHVHRTPTDRSQKRPIKGVTFSKEVIVVDLGNEDATPRSYAREHKERK", "length": 199 }, "evidence": [ { "id": "A0A061ILV0", "url": "https://omabrowser.org/oma/group/A0A061ILV0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q810S2-1", "protein_name": "Uncharacterized protein C2orf74 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTQSDTGKIEEIFTTNTMAFETTAITFFFILLICFICILLLLAIFLYKCYRGHNHEEPLKTLCTGEGCVAANAEMDKPEDQDKVLMHFLNMGLPMKPSILVQKQSKEEMATSLGDNIKAEDYQKKQTYEPVNARETNHEGELAEKMPIHVHRSSDTGSQKRPLKGVTFSKEVIVVDLGNEYPTPRSYAREHKERK", "length": 196 }, "evidence": [ { "id": "A0A061ILV0", "url": "https://omabrowser.org/oma/group/A0A061ILV0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061IM69-1", "uniprot_ac": "A0A061IM69", "uniprot_id": "A0A061IM69_CRIGR", "mass": { "chemical_mass": 81866.0, "monoisotopic_mass": 81866.0 }, "refseq": { "ac": "XP_007651059", "name": "ligand-dependent nuclear receptor-interacting factor 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651059" }, "gene_names": [ { "name": "Lrif1", "type": "recommended", "evidence": [ { "id": "A0A061IM69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IM69" } ] }, { "name": "Lrif1", "type": "synonym", "evidence": [ { "id": "XP_007651059", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651059" } ] } ], "protein_names": [ { "name": "Ligand-dependent nuclear receptor-interacting factor 1 isoform X4", "type": "synonym", "evidence": [ { "id": "A0A061IM69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IM69/entry#names_and_taxonomy" } ] }, { "name": "ligand-dependent nuclear receptor-interacting factor 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007651059", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651059" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615433.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007651059", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651059" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IM69", "url": "https://www.uniprot.org/uniprotkb/A0A061IM69" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Lrif1", "url": "https://www.uniprot.org/uniprotkb/A0A061IM69", "locus": {} } ], "crossref": [ { "id": "100773363", "url": "https://www.ncbi.nlm.nih.gov/gene/100773363", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026191", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026191", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773363", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773363", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061IM69", "url": "https://www.orthodb.org/?gene=A0A061IM69", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7F509", "url": "https://www.orthodb.org/?gene=A0A9J7F509", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JBD2", "url": "https://www.orthodb.org/?gene=A0A9J7JBD2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16131", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16131", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16131:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16131:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15741", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15741", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007651059", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651059", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IM69", "url": "https://www.uniprot.org/uniprotkb/A0A061IM69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IM69-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IM69-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F509", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F509", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F509-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F509-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F9K2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9K2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F9K2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F9K2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JBD2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JBD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JBD2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSNSLQSAFLKTAEEISGSGSHCVSGCMYQVVQMVGTDGKNLLKLLPIPKSSGNFTPVVQSPVVSDALKRNTGKPVQVTFQAQISSSSTSASVQLPIFQPADTTKCILTETIDTPGKGGITSVGTGSFIPPVSKVESHDVKIDGLNMQTFAIPPSTQDDSSHFVVSTPSLPVNVNSPVLPPGPHLQIPVHAEVKSIPELTLSPSVRQNIHATTTRSPSGNVEASQIPTVIYVSPANKVTNRVTKSFQKIYPKPVILNTAKIPPNVATETQLKSGQHSDTAQMKIIFQESLQTGIPSLVPVKSSNNVDSKISKTFIGRKKLRDNTINTPPLNTISSNGTQSISVPIKDNTLVMLNGKVYLLTKEGTHGLPSQNDHPNSVSSGNPLRKDSSQVVSSSPGTEISKELNSAFIQSKSCQLETKSLSNSQLASLTSLRAEKNETVARPSFSMASPHTVNQSSNYHKQSKTVFTDPVGFRTVQNAPRKGNLIQSIEKICSSVDAATVTSQQCVFRDQELQTQCEMASMLKKNTEERNKKYSEGSNTKASYLKSDAELKKLFGLTKDLRVGLTRIPDYLGSRKGSDSVSSLMKSSSYKDAEFVVKEEEIKQSFSKKRRAKNIKKMEYTKRRKIKRASDTVMNGTDVASSQLLSILPTSEVPQHNIVTSHSTTREDKRTEVEHCSHEKQDKGTLSSSVSFEQSNCFNKSYTEDIFLVTPPELEETIRDEKIRRLKQIVKEKEAALEEMRKKMHQKQ", "length": 748, "header": "tr|A0A061IM69-1|A0A061IM69_CRIGR Isoform 1 of Ligand-dependent nuclear receptor-interacting factor 1 isoform X4 OS=Cricetulus griseus OX=10029 GN=Lrif1 PE=4 SV=1 CANONICAL=A0A061IM69-1" }, "isoforms": [ { "isoform_ac": "A0A061IM69-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IM69/entry#A0A061IM69-1", "sequence": { "sequence": "MSNSLQSAFLKTAEEISGSGSHCVSGCMYQVVQMVGTDGKNLLKLLPIPKSSGNFTPVVQSPVVSDALKRNTGKPVQVTFQAQISSSSTSASVQLPIFQPADTTKCILTETIDTPGKGGITSVGTGSFIPPVSKVESHDVKIDGLNMQTFAIPPSTQDDSSHFVVSTPSLPVNVNSPVLPPGPHLQIPVHAEVKSIPELTLSPSVRQNIHATTTRSPSGNVEASQIPTVIYVSPANKVTNRVTKSFQKIYPKPVILNTAKIPPNVATETQLKSGQHSDTAQMKIIFQESLQTGIPSLVPVKSSNNVDSKISKTFIGRKKLRDNTINTPPLNTISSNGTQSISVPIKDNTLVMLNGKVYLLTKEGTHGLPSQNDHPNSVSSGNPLRKDSSQVVSSSPGTEISKELNSAFIQSKSCQLETKSLSNSQLASLTSLRAEKNETVARPSFSMASPHTVNQSSNYHKQSKTVFTDPVGFRTVQNAPRKGNLIQSIEKICSSVDAATVTSQQCVFRDQELQTQCEMASMLKKNTEERNKKYSEGSNTKASYLKSDAELKKLFGLTKDLRVGLTRIPDYLGSRKGSDSVSSLMKSSSYKDAEFVVKEEEIKQSFSKKRRAKNIKKMEYTKRRKIKRASDTVMNGTDVASSQLLSILPTSEVPQHNIVTSHSTTREDKRTEVEHCSHEKQDKGTLSSSVSFEQSNCFNKSYTEDIFLVTPPELEETIRDEKIRRLKQIVKEKEAALEEMRKKMHQKQ", "length": 748, "header": "tr|A0A061IM69-1|A0A061IM69_CRIGR Isoform 1 of Ligand-dependent nuclear receptor-interacting factor 1 isoform X4 OS=Cricetulus griseus OX=10029 GN=Lrif1 PE=4 SV=1 CANONICAL=A0A061IM69-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F509-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IM69/entry#A0A9J7F509-1", "sequence": { "sequence": "MASMLKKNTEERNKKYSEGSNTKASYLKSDAELKKLFGLTKDLRVGLTRIPDYLGSRKGSDSVSSLMKSSSYKDAEFVVKEEEIKQSFSKKRRAKNIKKMEYTKRRKIKRASDTVMNGTDVASSQLLSILPTSEVPQHNIVTSHSTTREDKRTEVEHCSHEKQDKGTLSSSVSFEQSNCFNKSYTEDIFLVTPPELEETIRDEKIRRLKQIVKEKEAALEEMRKKMHQKQ", "length": 230, "header": "tr|A0A9J7F509-1|A0A9J7F509_CRIGR Computationally mapped isoform of Ligand-dependent nuclear receptor-interacting factor 1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Lrif1 PE=4 SV=1 CANONICAL=A0A061IM69-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F9K2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IM69/entry#A0A9J7F9K2-1", "sequence": { "sequence": "MAGGTRARSRADKARPTQCEMASMLKKNTEERNKKYSEGSNTKASYLKSDAELKKLFGLTKDLRVGLTRIPDYLGSRKGSDSVSSLMKSSSYKDAEFVVKEEEIKQSFSKKRRAKNIKKMEYTKRRKIKRASDTVMNGTDVASSQLLSILPTSEVPQHNIVTSHSTTREDKRTEVEHCSHEKQDKGTLSSSVSFEQSNCFNKSYTEDIFLVTPPELEETIRDEKIRRLKQIVKEKEAALEEMRKKMHQKQ", "length": 250, "header": "tr|A0A9J7F9K2-1|A0A9J7F9K2_CRIGR Computationally mapped isoform of Ligand-dependent nuclear receptor-interacting factor 1 isoform X5 OS=Cricetulus griseus OX=10029 GN=Lrif1 PE=4 SV=1 CANONICAL=A0A061IM69-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JBD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IM69/entry#A0A9J7JBD2-1", "sequence": { "sequence": "MYQVVQMVGTDGKNLLKLLPIPKSSGNFTPVVQSPVVSDALKRNTGKPVQVTFQAQISSSSTSASVQLPIFQPADTTKCILTETIDTPGKGGITSVGTGSFIPPVSKVESHDVKIDGLNMQTFAIPPSTQDDSSHFVVSTPSLPVNVNSPVLPPGPHLQIPVHAEVKSIPELTLSPSVRQNIHATTTRSPSGNVEASQIPTVIYVSPANKVTNRVTKSFQKIYPKPVILNTAKIPPNVATETQLKSGQHSDTAQMKIIFQESLQTGIPSLVPVKSSNNVDSKISKTFIGRKKLRDNTINTPPLNTISSNGTQSISVPIKDNTLVMLNGKVYLLTKEGTHGLPSQNDHPNSVSSGNPLRKDSSQVVSSSPGTEISKELNSAFIQSKSCQLETKSLSNSQLASLTSLRAEKNETVARPSFSMASPHTVNQSSNYHKQSKTVFTDPVGFRTVQNAPRKGNLIQSIEKICSSVDAATVTSQQCVFRDQELQTQCEMASMLKKNTEERNKKYSEGSNTKASYLKSDAELKKLFGLTKDLRVGLTRIPDYLGSRKGSDSVSSLMKSSSYKDAEFVVKEEEIKQSFSKKRRAKNIKKMEYTKRRKIKRASDTVMNGTDVASSQLLSILPTSEVPQHNIVTSHSTTREDKRTEVEHCSHEKQDKGTLSSSVSFEQSNCFNKSYTEDIFLVTPPELEETIRDEKIRRLKQIVKEKEAALEEMRKKMHQKQ", "length": 721, "header": "tr|A0A9J7JBD2-1|A0A9J7JBD2_CRIGR Computationally mapped isoform of Ligand-dependent nuclear receptor-interacting factor 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Lrif1 PE=4 SV=1 CANONICAL=A0A061IM69-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IM69", "url": "https://www.uniprot.org/uniprotkb/A0A061IM69" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IM69", "url": "https://www.uniprot.org/uniprotkb/A0A061IM69" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773363", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773363", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A061IM69", "url": "https://www.uniprot.org/uniprotkb/A0A061IM69" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "nuclear retinoic acid receptor binding", "id": "GO:0042974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042974", "evidence": [ { "database": "UniProtKB", "id": "A0A061IM69", "url": "https://www.uniprot.org/uniprotkb/A0A061IM69" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 336, "end_pos": 338, "annotation": "n_glycosylation_sequon" }, { "start_pos": 437, "end_pos": 439, "annotation": "n_glycosylation_sequon" }, { "start_pos": 454, "end_pos": 456, "annotation": "n_glycosylation_sequon" }, { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" }, { "start_pos": 635, "end_pos": 637, "annotation": "n_glycosylation_sequon" }, { "start_pos": 699, "end_pos": 701, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 336, "end_pos": 338 }, { "start_pos": 437, "end_pos": 439 }, { "start_pos": 454, "end_pos": 456 }, { "start_pos": 54, "end_pos": 56 }, { "start_pos": 635, "end_pos": 637 }, { "start_pos": 699, "end_pos": 701 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { 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"recommended", "evidence": [ { "id": "A0A061IMA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IMA3" } ] }, { "name": "Cped1", "type": "synonym", "evidence": [ { "id": "XP_027245767", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027245767" } ] } ], "protein_names": [ { "name": "Cadherin-like and PC-esterase domain-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A061IMA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IMA3/entry#names_and_taxonomy" } ] }, { "name": "cadherin-like and PC-esterase domain-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027245767", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027245767" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027245767", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027245767" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IMA3", "url": "https://www.uniprot.org/uniprotkb/A0A061IMA3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cped1", "url": "https://www.uniprot.org/uniprotkb/A0A061IMA3", "locus": {} } ], "crossref": [ { "id": "100766134", "url": "https://www.ncbi.nlm.nih.gov/gene/100766134", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766134", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766134", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061IMA3", "url": "https://www.orthodb.org/?gene=A0A061IMA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14776", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14776", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14776:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14776:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12733", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12733", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027245767", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027245767", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IMA3", "url": "https://www.uniprot.org/uniprotkb/A0A061IMA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IMA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IMA3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F2N2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2N2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F2N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2N2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVCRPVFFCRRRFCPRPFLVGLVVAICLFYQTLTLRGTKKLAAEVPGTVRHTPSQTQASRCDQGYPWDKRCFLLSANALEIRKIEELIETHFGSHSRRAILFRSPSHSRPELQTLQHLLGQHGYSVVTVEERLGTGLGLELLDQGDLNSWDLLICLPSREADGKPCIAREHICRLRLHQKINVLPEIQPQLCRKEGLCQMIRRFPELRLPVSPSVCLDQGMQSQLSASSHLSKGAKPHVWKPWDGQSKQLNQTTVPVPREAILRAEELSVILKAYVLVTSLRPLRAFIHSTGTVWSPPKKKRFTVKLQMFFETFLRTSSPLQALDSMKEAISKLLLVAEVFSETSTLGPKTFHRCRQCFQLLTFDIGYGDSGHPVVLQVHEHLKVRDDENFNLEDQKTEKILLKDTFSFLFSNTSSLSLLSEQLQRLYREGVLEDGNYGKELNQCLSLEEIHSIRTFVKELGSLGEFQLLFPSTVPGIQSVMHEFYDMANPSSLLSRYWSLLNISEQFWPMNKKEQLHPLEWNSSTRNKTIQKTPESLEAIKSKEDAVPRVFHENKDIHCSNGKGTVCNIKIFTHPRLELNPEFNPKVKDYYCEVPFDVLTVRIGAETSKCQCKVHLQERAGPSFANYPLGLGMNRISMLVVDKSPAEGDTETTYKLSIYREDRPSLPFFEDFTACGFVQDCGLLIKPEETCGLQPISSDYIEAISQPKIESCPSGDTKGQWIVPCLSCSDNRTCDWREITWQPHNCQHNVLTKPELQQCLRGRKILFIGDSTNRGMMYYLIERLNETLQEWQKVHGTKLYPSVNGGKTLISYSYYPQFWISPSLRPTFEKALEHLLQRSHPLENTDQTVLVVGGVQWLNSQHLQIIHKVLKRENLLNILVIIKTLGIGFHLPVDGVHFLTQTEVQNLHKENLSILEAAKKYGYEVVDTFTITMGRHKEFLQGNCGCHFHEVVKSKLSREHHVIKMKRSKNHIVGKYFSSQNKLQRQNSVPNVHSPYHVRGPINQVCSEILLSRMCASQRSARAP", "length": 1025, "header": "tr|A0A061IMA3-1|A0A061IMA3_CRIGR Isoform 1 of Cadherin-like and PC-esterase domain-containing protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Cped1 PE=4 SV=1 CANONICAL=A0A061IMA3-1" }, "isoforms": [ { "isoform_ac": "A0A061IMA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IMA3/entry#A0A061IMA3-1", "sequence": { "sequence": "MVCRPVFFCRRRFCPRPFLVGLVVAICLFYQTLTLRGTKKLAAEVPGTVRHTPSQTQASRCDQGYPWDKRCFLLSANALEIRKIEELIETHFGSHSRRAILFRSPSHSRPELQTLQHLLGQHGYSVVTVEERLGTGLGLELLDQGDLNSWDLLICLPSREADGKPCIAREHICRLRLHQKINVLPEIQPQLCRKEGLCQMIRRFPELRLPVSPSVCLDQGMQSQLSASSHLSKGAKPHVWKPWDGQSKQLNQTTVPVPREAILRAEELSVILKAYVLVTSLRPLRAFIHSTGTVWSPPKKKRFTVKLQMFFETFLRTSSPLQALDSMKEAISKLLLVAEVFSETSTLGPKTFHRCRQCFQLLTFDIGYGDSGHPVVLQVHEHLKVRDDENFNLEDQKTEKILLKDTFSFLFSNTSSLSLLSEQLQRLYREGVLEDGNYGKELNQCLSLEEIHSIRTFVKELGSLGEFQLLFPSTVPGIQSVMHEFYDMANPSSLLSRYWSLLNISEQFWPMNKKEQLHPLEWNSSTRNKTIQKTPESLEAIKSKEDAVPRVFHENKDIHCSNGKGTVCNIKIFTHPRLELNPEFNPKVKDYYCEVPFDVLTVRIGAETSKCQCKVHLQERAGPSFANYPLGLGMNRISMLVVDKSPAEGDTETTYKLSIYREDRPSLPFFEDFTACGFVQDCGLLIKPEETCGLQPISSDYIEAISQPKIESCPSGDTKGQWIVPCLSCSDNRTCDWREITWQPHNCQHNVLTKPELQQCLRGRKILFIGDSTNRGMMYYLIERLNETLQEWQKVHGTKLYPSVNGGKTLISYSYYPQFWISPSLRPTFEKALEHLLQRSHPLENTDQTVLVVGGVQWLNSQHLQIIHKVLKRENLLNILVIIKTLGIGFHLPVDGVHFLTQTEVQNLHKENLSILEAAKKYGYEVVDTFTITMGRHKEFLQGNCGCHFHEVVKSKLSREHHVIKMKRSKNHIVGKYFSSQNKLQRQNSVPNVHSPYHVRGPINQVCSEILLSRMCASQRSARAP", "length": 1025, "header": "tr|A0A061IMA3-1|A0A061IMA3_CRIGR Isoform 1 of Cadherin-like and PC-esterase domain-containing protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Cped1 PE=4 SV=1 CANONICAL=A0A061IMA3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F2N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IMA3/entry#A0A9J7F2N2-1", "sequence": { "sequence": "MVCRPVFFCRRRFCPRPFLVGLVVAICLFYQTLTLRGTKKLAAEVPGTVRHTPSQTQASRCDQGYPWDKRCFLLSANALEIRKIEELIETHFGSHSRRAILFRSPSHSRPELQTLQHLLGQHGYSVVTVEERLGTGLGLELLDQGDLNSWDLLICLPSREADGKPCIAREHICRLRLHQKINVLPEIQPQLCRKEGLCQMIRRFPELRLPVSPSVCLDQGMQSQLSASSHLSKGAKPHVWKPWDGQSKQLNQTTVPVPREAILRAEELSVILKAYVLVTSLRPLRAFIHSTGTVWSPPKKKRFTVKLQMFFETFLRTSSPLQALDSMKEAISKLLLVAEVFSETSTLGPKTFHRCRQCFQLLTFDIGYGDSGHPVVLQVHEHLKVRDDENFNLEDQKTEKILLKDTFSFLFSNTSSLSLLSEQLQRLYREGVLEDGNYGKELNQCLSLEEIHSIRTFVKELGSLGEFQLLFPSTVPGIQSVMHEFYDMANPSSLLSRYWSLLNISEQFWPMNKKEQLHPLEWNSSTRNKTIQKTPESLEAIKSKEDAVPRVFHENKDIHCSNGKGTVCNIKIFTHPRLELNPEFNPKVKDYYCEVPFDVLTVRIGAETSKCQCKVHLQERAGPSFANYPLGLGMNRISMLVVDKSPAEGDTETTYKLSIYREDRPSLPFFEDFTACGFVQDCGLLIKPEETCGLQPISSDYIEAISQPKIESCPSGDTKGQWIVPCLSCSDNRTCDWREITWQPHNCQHNVLTKPELQQCLRGRKILFIGDSTNRGMMYYLIERLNETLQEWQKVHGTKLYPSVNGGKTLISYSYYPQFWISPSLRPTFEKALEHLLQRSHPLENTDQTVLVVGGVQWLNSQHLQIIHKVLKRENLLNILVIIKTLGIGFHLPVDGVHFLTQTEVQNLHKENLSILEAAKKYGYEVVDTFTITMGRHKEFLQGNCGCHFHETGAEIS", "length": 957, "header": "tr|A0A9J7F2N2-1|A0A9J7F2N2_CRIGR Computationally mapped isoform of Cadherin-like and PC-esterase domain-containing protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Cped1 PE=4 SV=1 CANONICAL=A0A061IMA3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"MKLDSAEEESRGVPSPLAEGSPSTLELAFSKILHGLSRPESGQGNARTAVLQDLGALIEAAECDELCEGTRSGDSLRGMPEILGQVAKALEKLAAPPKEKAEGGDGHSEVAGKATEVGLLFLKLLGKVEAAKSSPACPAWKTGLRHLAGPAYVFATTHRLKQPWTSPRSQRVADEVLSLLLRVTECSSVAGFLCGENEDDRGRFAVVLGLLKPHLNKESWKNNPAVKHVFSWSLQQVTQPWLSQHLEKILPPSLLISDDYQTENKILGVQCLHHIVINVPAADLLQYNRAQVLYHALFNHLYMPEHHLIQAVLLCLLDLFPVLEKGLHWKGDAVRATTHCHDVLQLILTHMEPEHRLLLRRTYARNLPAFVRKLGILTVRHLKRLEPVIIGYLEVYDGPEEETRLKILETLKLVMQYAWPRIPCRVVVLLKALLKLICDVARDTSLTTEATKCTLLQEATDCLILLDHCSQGQVKGLLSKIVLSCEDHTVVNCIRRVQQSSAAVPCDDS", "length": 509, "header": "tr|A0A061IMU4-1|A0A061IMU4_CRIGR Isoform 1 of TELO2-interacting protein 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tti2 PE=3 SV=1 CANONICAL=A0A061IMU4-1" }, "isoforms": [ { "isoform_ac": "A0A061IMU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IMU4/entry#A0A061IMU4-1", "sequence": { "sequence": "MKLDSAEEESRGVPSPLAEGSPSTLELAFSKILHGLSRPESGQGNARTAVLQDLGALIEAAECDELCEGTRSGDSLRGMPEILGQVAKALEKLAAPPKEKAEGGDGHSEVAGKATEVGLLFLKLLGKVEAAKSSPACPAWKTGLRHLAGPAYVFATTHRLKQPWTSPRSQRVADEVLSLLLRVTECSSVAGFLCGENEDDRGRFAVVLGLLKPHLNKESWKNNPAVKHVFSWSLQQVTQPWLSQHLEKILPPSLLISDDYQTENKILGVQCLHHIVINVPAADLLQYNRAQVLYHALFNHLYMPEHHLIQAVLLCLLDLFPVLEKGLHWKGDAVRATTHCHDVLQLILTHMEPEHRLLLRRTYARNLPAFVRKLGILTVRHLKRLEPVIIGYLEVYDGPEEETRLKILETLKLVMQYAWPRIPCRVVVLLKALLKLICDVARDTSLTTEATKCTLLQEATDCLILLDHCSQGQVKGLLSKIVLSCEDHTVVNCIRRVQQSSAAVPCDDS", "length": 509, "header": "tr|A0A061IMU4-1|A0A061IMU4_CRIGR Isoform 1 of TELO2-interacting protein 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tti2 PE=3 SV=1 CANONICAL=A0A061IMU4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HDJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IMU4/entry#A0A9J7HDJ9-1", "sequence": { "sequence": "MKLDSAEEESRGVPSPLAEGSPSTLELAFSKILHGLSRPESGQGNARTAVLQDLGALIEAAECDELCEGTRSGDSLRGMPEILGQVAKALEKLAAPPKEKAEGGDGHSEVAGKATEVGLLFLKLLGKVEAAKSSPACPAWKTGLRHLAGPAYVFATTHRLKQPWTSPRSQRVADEVLSLLLRVTECSSVAGFLCGENEDDRGRFAVVLGLLKPHLNNLQQVTQPWLSQHLEKILPPSLLISDDYQTENKILGVQCLHHIVINVPAADLLQYNRAQVLYHALFNHLYMPEHHLIQAVLLCLLDLFPVLEKGLHWKGDAVRATTHCHDVLQLILTHMEPEHRLLLRRTYARNLPAFVRKLGILTVRHLKRLEPVIIGYLEVYDGPEEETRLKILETLKLVMQYAWPRIPCRVVVLLKALLKLICDVARDTSLTTEATKCTLLQEATDCLILLDHCSQGQVKGLLSKIVLSCEDHTVVNCIRRVQQSSAAVPCDDS", "length": 493, "header": "tr|A0A9J7HDJ9-1|A0A9J7HDJ9_CRIGR Computationally mapped isoform of TELO2-interacting protein 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Tti2 PE=3 SV=1 CANONICAL=A0A061IMU4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IMU4", "url": "https://www.uniprot.org/uniprotkb/A0A061IMU4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IMU4", "url": "https://www.uniprot.org/uniprotkb/A0A061IMU4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760553", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760553", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A061IMU4", "url": "https://www.uniprot.org/uniprotkb/A0A061IMU4" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A061IMU4", "url": "https://www.uniprot.org/uniprotkb/A0A061IMU4" } ], "pmid": "" }, { "name": "TTT Hsp90 cochaperone complex", "id": "GO:0110078", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0110078", "evidence": [ { "database": "UniProtKB", "id": "A0A061IMU4", "url": "https://www.uniprot.org/uniprotkb/A0A061IMU4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061IN65-1", "uniprot_ac": "A0A061IN65", "uniprot_id": "A0A061IN65_CRIGR", "mass": { "chemical_mass": 24862.0, "monoisotopic_mass": 24862.0 }, "refseq": { "ac": "XP_003502999", "name": "coiled-coil domain-containing protein 169", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502999" }, "gene_names": [ { "name": "Ccdc169", "type": "recommended", "evidence": [ { "id": "A0A061IN65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IN65" } ] }, { "name": "Ccdc169", "type": "synonym", "evidence": [ { "id": "XP_003502999", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502999" } ] } ], "protein_names": [ { "name": "Coiled-coil domain-containing protein 169", "type": "synonym", "evidence": [ { "id": "A0A061IN65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IN65/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 169", "type": "synonym", "evidence": [ { "id": "XP_003502999", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502999" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613925.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003502999", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502999" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IN65", "url": "https://www.uniprot.org/uniprotkb/A0A061IN65" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ccdc169", "url": "https://www.uniprot.org/uniprotkb/A0A061IN65", "locus": {} } ], "crossref": [ { "id": "100767466", "url": "https://www.ncbi.nlm.nih.gov/gene/100767466", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028022", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028022", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767466", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767466", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MPVGSLN", "url": "https://omabrowser.org/oma/group/MPVGSLN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061IN65", "url": "https://www.orthodb.org/?gene=A0A061IN65", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28671", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28671", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28671:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28671:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15372", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15372", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003502999", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502999", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IN65", "url": "https://www.uniprot.org/uniprotkb/A0A061IN65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IN65-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IN65-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGEGRGDTFEGVSTDRLKLELLEEIHMKDVVQLSMLEIRHKIAELEASVNSEHAGNEWKTRYETQMELNDQLEKQIVSLKEKMEKVRGNPSDRLSSIRVYERMPLESLNTLLKQLEKEKRSLESQVKDYALKLEQESKAYHRTNNERRTYIAEMSQVSGLNQVSKKQQMDALPRMKENLVKTGRYNPVNQKIMNAKKGPVKKVSRSNHLPKLNP", "length": 214, "header": "tr|A0A061IN65-1|A0A061IN65_CRIGR Isoform 1 of Coiled-coil domain-containing protein 169 OS=Cricetulus griseus OX=10029 GN=Ccdc169 PE=4 SV=1 CANONICAL=A0A061IN65-1" }, "isoforms": [ { "isoform_ac": "A0A061IN65-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IN65/entry#A0A061IN65-1", "sequence": { "sequence": "MGEGRGDTFEGVSTDRLKLELLEEIHMKDVVQLSMLEIRHKIAELEASVNSEHAGNEWKTRYETQMELNDQLEKQIVSLKEKMEKVRGNPSDRLSSIRVYERMPLESLNTLLKQLEKEKRSLESQVKDYALKLEQESKAYHRTNNERRTYIAEMSQVSGLNQVSKKQQMDALPRMKENLVKTGRYNPVNQKIMNAKKGPVKKVSRSNHLPKLNP", "length": 214, "header": "tr|A0A061IN65-1|A0A061IN65_CRIGR Isoform 1 of Coiled-coil domain-containing protein 169 OS=Cricetulus griseus OX=10029 GN=Ccdc169 PE=4 SV=1 CANONICAL=A0A061IN65-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IN65", "url": "https://www.uniprot.org/uniprotkb/A0A061IN65" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IN65", "url": "https://www.uniprot.org/uniprotkb/A0A061IN65" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767466", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767466", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XL96-1", "protein_name": "Coiled-coil domain containing 169", "gene_name": "CCDC169", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGERGDSEGLDMELGRERRRQQMLENSISELRKTVTELEKKLSSVEDEGNEWKTRYEMQVELNSQLQRQIHILKDKVELIRGNPTDKLAIVRIFDQMPVDSLKEVLEQLKEEKKSLQNQLKDYELRLEQEAKAYHKANDERRMYLAEILQTSAMLKTVEKQKTDALTSKGEKWALRGRCSVPQSLKMVNPQKGPIKKTAGVKQLPNLKP", "length": 209 }, "evidence": [ { "id": "A0A061IN65", "url": "https://omabrowser.org/oma/group/A0A061IN65/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A6NNP5-1", "protein_name": "Coiled-coil domain-containing protein 169", "gene_name": "CCDC169", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKEERNYNFDGVSTNRLKQQLLEEVRKKDAVQLSIFELRHKITELEAKLNTDNEGSEWKTRYETQLELNDELEKQIVYLKEKVEKIHGNSSDRLSSIRVYERMPVESLNTLLKQLEEEKKTLESQVKYYALKLEQESKAYQKINNERRTYLAEMSQGSGLHQVSKRQQVDQLPRMQENLVKTGRYNPAKQKTVSAKRGPVKKITRPNHLPELHP", "length": 214 }, "evidence": [ { "id": "A0A061IN65", "url": "https://omabrowser.org/oma/group/A0A061IN65/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BXX9-1", "protein_name": "Coiled-coil domain-containing protein 169", "gene_name": "Ccdc169", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"MAGARAALLLPLLLQLGSLALAARGGEVSRKRPRLADILDYQQQAPSHSLLPAEGPQQQWCPLKERLERLEAEVTDLRKQNRDLQARVTRLESCDCCSASPQCRGLGHTCPEGARWEPDACTACVCRDGTAHCGPQPNLPHCPGCSHNGQSYGHEETFSPDACTTCRCLAGTVQCQGPSCSKLNCLETLTPPGECCPVCRPGCEYEGQLHEEGASFLSSSNPCLQCSCLGSLVQCVPVKCLPSPCPEPVLRPGHCCPACQTPGCTEGNSHREHGQEWTTPGDPCRICQCLEGHIQCRQKECASLCPYPARPLPGTCCPVCDGCFLNGREHSSGEPVGSQDPCSSCRCTNGSVQCEPLPCPPAPCRYPGRIRGQCCPVCDGCQYQGHEYQSQETFTLQENGRCLRCSCQAGEVSCEEQGCPVAPCTRSASGPQLCSACVLNGEEFAEGIQWEPDGQPCTTCSCQDGMPVCRAVLCSPVLCQHPTQPPGACCPSCESCAYRGLVYNNGQNFTDVDNPCQICHCEDGTVRCSSVNCPATTCTKPQSGPGQCCPKCPDCILETQVFVDGERFPHPRDPCQECHCQEGQAHCQPRACPSAPCGHPLPSTCCRTDCKGCAFGGKEYPNGADFPHPTDPCRLCRCLGGNAQCLARRCPPLSCPEPVLPPGECCPQCPDAPAGCPQSGDAVPARHQEHFFPPGDPCSRCLCLDGSVSCRRLPCPPAPCAHPRRGPCCPSCDGCLYQGKEFASGQRFPSPSIACHVCLCWEGSVNCEPKACAPAQCPFPAREDCCPTCDSCEYLGVSYLSSQEFPDPREPCSLCTCLGGFVTCTRQPCEPPACSHPLIISGHCCPTCQGCLYHGITAALGETLPDPLDPACSLCTCQEGSMRCQKKPCPPALCSHPAPGPCFCPVCRSCLSHGQEHQDGEEFEGPEGSCERCHCWAGRVSCMRVQCAPLPCLLQVTEPGSCCPRCTGCLAHGEEHPEGSIWVPANSPCSTCMCHKGTITCAQVQCVSACRQPQQEPSACCPPCSGCEHEGRKYEPGESFQPGADPCEVCTCELQPEKPPSLHCRRRQCPILVGCPPSQLLPPGPQRCCPTCAQALSNCTEDLLGTELMPPDPCYACQCQDLTWLCTHRACPELSCPLWERHTPTGSCCPMCKAPTQSCMHRGRQVASGEHWTVDACTSCFCVAGIVRCQSQRCSKLACGQDEAPALSPGSCCPRCLPRPASCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSDDFSVHVTNDDRGRRGVAWTQEVAVLLGTVAVRLLQGRTVMVDQHTVTLPFLREGLLFVELRGRTVILHAQPGLQVLWDGQSQVEVRVPSSYRGQTCGLCGNFNGFAQDDLRGPDGRFLPTEAAFGNSWKVPEELGPSQPCSAGREVDPCRAAGYRARREANARCGLLKTSTFSHCHAVVPPEPFFAACVYDLCACGPGSSADTCLCDVLEAYASHCRQAGVTPVWRGPTLCVVGCPMDRGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVPGCQCPAGLVEHEGHCISPEACPPVLLTGDNPSQEQPLVPPGVKNALS", "length": 1577, "header": "tr|A0A061IN98-1|A0A061IN98_CRIGR Isoform 1 of Kielin/chordin-like protein OS=Cricetulus griseus OX=10029 GN=Kcp PE=4 SV=1 CANONICAL=A0A061IN98-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IN98", "url": "https://www.uniprot.org/uniprotkb/A0A061IN98" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IN98", "url": "https://www.uniprot.org/uniprotkb/A0A061IN98" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761131", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761131", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A061IN98", "url": "https://www.uniprot.org/uniprotkb/A0A061IN98" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of BMP signaling pathway", "id": "GO:0030513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030513", "evidence": [ { "database": "UniProtKB", "id": "A0A061IN98", "url": "https://www.uniprot.org/uniprotkb/A0A061IN98" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1098, "end_pos": 1100, "annotation": "n_glycosylation_sequon" }, { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 508, "end_pos": 510, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061IN98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IN98" }, { "id": "PS50184", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50184" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFC", "eco_id": "ECO_0000259", "start_pos": 143, "end_pos": 200, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A061IN98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IN98" }, { "id": "PS51233", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51233" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFD", "eco_id": "ECO_0000259", "start_pos": 1221, "end_pos": 1397, "start_aa": "Ala", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1098, "end_pos": 1100 }, { "start_pos": 349, "end_pos": 351 }, { "start_pos": 508, "end_pos": 510 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"XP_007647803", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007647803" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614620.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007647803", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007647803" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061INE8", "url": "https://www.uniprot.org/uniprotkb/A0A061INE8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Prickle4", "url": "https://www.uniprot.org/uniprotkb/A0A061INE8", "locus": {} } ], "crossref": [ { "id": "cd09340", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09340", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09341", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09341", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09828", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09828", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100772474", "url": "https://www.ncbi.nlm.nih.gov/gene/100772474", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010442", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010442", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047120", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047120", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772474", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772474", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LNSGWPH", "url": "https://omabrowser.org/oma/group/LNSGWPH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061INE8", "url": "https://www.orthodb.org/?gene=A0A061INE8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7F746", "url": "https://www.orthodb.org/?gene=A0A9J7F746", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24211", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24211", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24211:SF35", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24211:SF35", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06297", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06297", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007647803", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007647803", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061INE8", "url": "https://www.uniprot.org/uniprotkb/A0A061INE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061INE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A061INE8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F746", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F746", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F746-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F746-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAQ1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J8P6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8P6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J8P6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8P6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVQNSDWSLQQNCPIFREPDPPISSDSHSGHQLVECYMDTSGQASTDSSLGPPCLDINQASNWPEFRILLQQLPPQDSDEHYCLALGEDELAQLRLFCAQRKQKSLGQGVARLLPPKLEGHTCEKCKKLLNPGEYGVFAARAGEQSCWHRACFACQACGQALINLIYFYHDGHLYCGRHHAELLRPRCPACDQLIFSQRCTEAEGRRWHENHFCCQDCAGPLGAGPYALPGGSPCCPSCFENRYQSAGSNSEEAPEGHASLGGTGPDPSVGWNRACSDDKIIFRDGLFSTVASSTLGPPSPASKGQDRDRPQTPGNPKEDSFCPTCSSSSESEPEGFFFGQRLPGPWKTPENLQADDRDISRKHCTIC", "length": 369, "header": "tr|A0A061INE8-1|A0A061INE8_CRIGR Isoform 1 of Prickle-like protein 4 isoform X1 OS=Cricetulus griseus OX=10029 GN=Prickle4 PE=4 SV=1 CANONICAL=A0A061INE8-1" }, "isoforms": [ { "isoform_ac": "A0A061INE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A061INE8/entry#A0A061INE8-1", "sequence": { "sequence": "MSVQNSDWSLQQNCPIFREPDPPISSDSHSGHQLVECYMDTSGQASTDSSLGPPCLDINQASNWPEFRILLQQLPPQDSDEHYCLALGEDELAQLRLFCAQRKQKSLGQGVARLLPPKLEGHTCEKCKKLLNPGEYGVFAARAGEQSCWHRACFACQACGQALINLIYFYHDGHLYCGRHHAELLRPRCPACDQLIFSQRCTEAEGRRWHENHFCCQDCAGPLGAGPYALPGGSPCCPSCFENRYQSAGSNSEEAPEGHASLGGTGPDPSVGWNRACSDDKIIFRDGLFSTVASSTLGPPSPASKGQDRDRPQTPGNPKEDSFCPTCSSSSESEPEGFFFGQRLPGPWKTPENLQADDRDISRKHCTIC", "length": 369, "header": "tr|A0A061INE8-1|A0A061INE8_CRIGR Isoform 1 of Prickle-like protein 4 isoform X1 OS=Cricetulus griseus OX=10029 GN=Prickle4 PE=4 SV=1 CANONICAL=A0A061INE8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F746-1", "url": "https://www.uniprot.org/uniprotkb/A0A061INE8/entry#A0A9J7F746-1", "sequence": { "sequence": "MRSLPFYLSPAQHLSLREHFNPSEVWVDGGLFLQEHYCLALGEDELAQLRLFCAQRKQKSLGQGVARLLPPKLEGHTCEKCKKLLNPGEYGVFAARAGEQSCWHRACFACQACGQALINLIYFYHDGHLYCGRHHAELLRPRCPACDQLIFSQRCTEAEGRRWHENHFCCQDCAGPLGAGPYALPGGSPCCPSCFENRYQSAGSNSEEAPEGHASLGGTGPDPSVGWNRACSDDKIIFRDGLFSTVASSTLGPPSPASKGQDRDRPQTPGNPKEDSFCPTCSSSSESEPEGFFFGQRLPGPWKTPENLQADDRDISRKHCTIC", "length": 323, "header": "tr|A0A9J7F746-1|A0A9J7F746_CRIGR Computationally mapped isoform of Prickle-like protein 4 isoform X4 OS=Cricetulus griseus OX=10029 GN=Prickle4 PE=4 SV=1 CANONICAL=A0A061INE8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HAQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A061INE8/entry#A0A9J7HAQ1-1", "sequence": { "sequence": "MSVQNSDWSLQQNCPIFREPDPPISSDSHSGHQLVECYMDTSGQASTDSSLGPPCLDINQASNWPEFRILLQQLPPQDSDEHYCLALGEDELAQLRLFCAQRKQKSLGQGVARLLPPKLEGHTCEKACGQALINLIYFYHDGHLYCGRHHAELLRPRCPACDQLIFSQRCTEAEGRRWHENHFCCQDCAGPLGAGPYALPGGSPCCPSCFENRYQSAGSNSEEAPEGHASLGGTGPDPSVGWNRACSDDKIIFRDGLFSTVASSTLGPPSPASKGQDRDRPQTPGNPKEDSFCPTCSSSSESEPEGFFFGQRLPGPWKTPENLQADDRDISRKHCTIC", "length": 338, "header": "tr|A0A9J7HAQ1-1|A0A9J7HAQ1_CRIGR Computationally mapped isoform of Prickle-like protein 4 isoform X3 OS=Cricetulus griseus OX=10029 GN=Prickle4 PE=4 SV=1 CANONICAL=A0A061INE8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J8P6-1", "url": "https://www.uniprot.org/uniprotkb/A0A061INE8/entry#A0A9J7J8P6-1", "sequence": { "sequence": "MSVQNSDWSLQQNCPIFREPDPPISSDSHSGHQLVECYMDTSGQASTDSSLGPPCLDINQASNWPEFRILLQQLPPQDSDEHYCLALGEDELAQLRLFCAQRKQKSLGQGVARLLPPKLEGHTCEKCKKLLNPGEYGVFAARAGEQSCWHRACFACQACGQALINLIYFYHDGHLYCGRHHAELLRPRCPACDQLIFSQRCTEAEGRRWHENHFCCQDCAGPLGAGPYALPGGSPCCPSCFENRYQSAGSNSEEAPEGHASLVASSTLGPPSPASKGQDRDRPQTPGNPKEDSFCPTCSSSSESEPEGFFFGQRLPGPWKTPENLQADDRDISRKHCTIC", "length": 340, "header": "tr|A0A9J7J8P6-1|A0A9J7J8P6_CRIGR Computationally mapped isoform of Prickle-like protein 4 isoform X2 OS=Cricetulus griseus OX=10029 GN=Prickle4 PE=4 SV=1 CANONICAL=A0A061INE8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061INE8", "url": "https://www.uniprot.org/uniprotkb/A0A061INE8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061INE8", "url": "https://www.uniprot.org/uniprotkb/A0A061INE8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100772474", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772474", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LU11-1", "protein_name": "Prickle planar cell polarity protein 4", "gene_name": "PRICKLE4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTLPPVSLLNSGWPHRVKRLASPELNPPVNSDSDPETMPKEDPEETSAQDPEVLSWGHPGLDTTPAPSWPVLRSLLQQLPPQDSDERYCLALGEEELAELRLFCAQRRREALGQGVACLVPLKLEECTCENCRERLRPGEYGVFAARAGERRCWHRACFACQACGQALINLIYFYHDGRLYCGRHHAELLRPRCPACDQLIFSRRCTEAEGRRWHENHFCCQDCAGPLGGGRYALPGGGPCCPSCFERRYSDVGSSPAPTLESRASPGEEGLCRVGAPDCAQLNAATISRATLLATAASSSLETRTEMLGSSAEQEYRAGDQTEARQGQAQGRLETPLDPKEDAPCPTCSSSSESEPEGFFLGQRLPRPWETPASLQTGYSDTSRRHCTIC", "length": 391 }, "evidence": [ { "id": "A0A061INE8", "url": "https://omabrowser.org/oma/group/A0A061INE8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3Z6Q6-1", "protein_name": "Prickle planar cell polarity protein 4", "gene_name": "Prickle4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVQNSDWSLQQDNPIFREPDPPVYTDSDSGRRPVEDYEDTSAQAATCSSLGPPCLDINQVSNWPGFRTLLQQLPPQDSDERYCLALGEEELAQLRLFCAQRKQKSLGQGVARLLPPKLEGYTCKKCKKLLDPGEYGVFAARAGEQSCWHRPCFACQACGQGLINLIYFYHEGHLYCGRHHAELLRPRCPACDQLIFSQRCTEAEGQRWHENHFCCQDCAGPLDGGRYALPGGSPCCPSCFSKRYRSAGSSSVGVAEGQASFEEEGPDPSVGWNRASSDDKITSRAALLSAVPTLTLETLNGASKRQDRDGPQTPGSPIEDSPCPTCSSSSESEPEGFFFGQRLPEPWKTPENLQADDRDISRKHCTIC", "length": 369 }, "evidence": [ { "id": "A0A061INE8", "url": "https://omabrowser.org/oma/group/A0A061INE8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1M759-1", "protein_name": "Prickle planar cell polarity protein 4", "gene_name": "Prickle4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVQNSDWSLQQDNPIFREPDPPVNTDSDSGHRPVQGYGDISVQAPTSSSLGPPCPDISQASNWPGFRTLLQQLPPQDSDERYCLALGEEELAQLRLFCAQRKQKSLGQGVARLLPPKLEGHTCEKCKKLLNPGEYGVFAARAGERCCWHRPCFACQACGQALTNLIYFYHDGHLYCGRHHAELLRPRCPACDQLIFSQRCTEAEGRHWHENHFCCQDCAEPLDGGRYALPGGSPCCPSCFARRYRSGGSSSIGAAEGQASLEGPDPSVGWNRASSDDKITSRAALPSAVAIPSEASKQRDRNSPQTPKEGSPCPTCSSSSESEPEGYFFGQRLPDLWKTPENLQADDRGISRKHCAIC", "length": 359 }, "evidence": [ { "id": "A0A061INE8", "url": "https://omabrowser.org/oma/group/A0A061INE8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2TBC4-1", "protein_name": "Prickle-like protein 4", "gene_name": "PRICKLE4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSPQGPAVLSLGSLCLDTNQAPNWTGLQTLLQQLPPQDIDERYCLALGEEERAELQLFCARRKQEALGQGVARLVLPKLEGHTCEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIFSWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSCFENRYSDAGSSWAGALEGQAFLGETGLDRTEGRDQTSVNSATLSRTLLAAAGGSSLQTQRGLPGSSPQQENRPGDKAEAPKGQEQCRLETIRDPKDTPFSTCSSSSDSEPEGFFLGERLPQSWKTPGSLQAEDSNASKTHCTMC", "length": 344 }, "evidence": [ { "id": "A0A061INE8", "url": "https://omabrowser.org/oma/group/A0A061INE8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A061INE8", "url": "https://www.uniprot.org/uniprotkb/A0A061INE8" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A061INE8", "url": "https://www.uniprot.org/uniprotkb/A0A061INE8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061INE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061INE8" }, { "id": "PS50023", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50023" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding", "eco_id": "ECO_0000259", "start_pos": 122, "end_pos": 187, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A061INE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061INE8" }, { "id": "PS51303", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51303" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PET", "eco_id": "ECO_0000259", "start_pos": 68, "end_pos": 120, "start_aa": "Arg", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061INM9-1", "uniprot_ac": "A0A061INM9", "uniprot_id": "A0A061INM9_CRIGR", "mass": { "chemical_mass": 39571.0, "monoisotopic_mass": 39571.0 }, "refseq": { "ac": "XP_016827362", "name": "circadian-associated transcriptional repressor isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016827362" }, "gene_names": [ { "name": "Ciart", "type": "recommended", "evidence": [ { "id": "A0A061INM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061INM9" } ] }, { "name": "Ciart", "type": "synonym", "evidence": [ { "id": "XP_016827362", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016827362" } ] } ], "protein_names": [ { "name": "Circadian-associated transcriptional repressor isoform X1", "type": "synonym", "evidence": [ { "id": "A0A061INM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061INM9/entry#names_and_taxonomy" } ] }, { "name": "circadian-associated transcriptional repressor isoform X1", "type": "synonym", "evidence": [ { "id": "XP_016827362", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016827362" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613699.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016827362", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016827362" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061INM9", "url": "https://www.uniprot.org/uniprotkb/A0A061INM9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ciart", "url": "https://www.uniprot.org/uniprotkb/A0A061INM9", "locus": {} } ], "crossref": [ { "id": "100761544", "url": "https://www.ncbi.nlm.nih.gov/gene/100761544", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761544", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761544", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061INM9", "url": "https://www.orthodb.org/?gene=A0A061INM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35441", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35441", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35441:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35441:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15673", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15673", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016827362", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016827362", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061INM9", "url": "https://www.uniprot.org/uniprotkb/A0A061INM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061INM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A061INM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H826", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H826", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H826-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H826-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSPSSVSSYCSSSLSSSFSTSPVNSDFSFPSDNEREGKSAHGLRPEDVGQRGGSRPSPGPIRCRHRLRVSSNQHTASHLEQRGSRVKGSRDGELGTSLHTQGCTTEGDLLFAQKCEELQGFIRPLTDLLNGLKMGRFDRGLSSFQQSVAMDRIQRIVGVLRKPQMGERYLGTLLQVEGMLKTWFPRIAAQKSSLGGSRHQISKHFPSHHSDSAASSPAPLMEKMGQTQLGHLVLKPKQPWHLTEWPAMNLTWIHSTPICNPPLSSQGSNSAHSSIGTGASIGVILVLQKGGQPFTHSALGTPIPPTTLSPVIPGDLKKLSREGPCYHSLPVTLPSDWSCTLCPPVLPTTVREMTTGHLESAVAPGP", "length": 367, "header": "tr|A0A061INM9-1|A0A061INM9_CRIGR Isoform 1 of Circadian-associated transcriptional repressor isoform X1 OS=Cricetulus griseus OX=10029 GN=Ciart PE=4 SV=1 CANONICAL=A0A061INM9-1" }, "isoforms": [ { "isoform_ac": "A0A061INM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A061INM9/entry#A0A061INM9-1", "sequence": { "sequence": "MDSPSSVSSYCSSSLSSSFSTSPVNSDFSFPSDNEREGKSAHGLRPEDVGQRGGSRPSPGPIRCRHRLRVSSNQHTASHLEQRGSRVKGSRDGELGTSLHTQGCTTEGDLLFAQKCEELQGFIRPLTDLLNGLKMGRFDRGLSSFQQSVAMDRIQRIVGVLRKPQMGERYLGTLLQVEGMLKTWFPRIAAQKSSLGGSRHQISKHFPSHHSDSAASSPAPLMEKMGQTQLGHLVLKPKQPWHLTEWPAMNLTWIHSTPICNPPLSSQGSNSAHSSIGTGASIGVILVLQKGGQPFTHSALGTPIPPTTLSPVIPGDLKKLSREGPCYHSLPVTLPSDWSCTLCPPVLPTTVREMTTGHLESAVAPGP", "length": 367, "header": "tr|A0A061INM9-1|A0A061INM9_CRIGR Isoform 1 of Circadian-associated transcriptional repressor isoform X1 OS=Cricetulus griseus OX=10029 GN=Ciart PE=4 SV=1 CANONICAL=A0A061INM9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H826-1", "url": "https://www.uniprot.org/uniprotkb/A0A061INM9/entry#A0A9J7H826-1", "sequence": { "sequence": "MDSPSSVSSYCSSSLSSSFSTSPVNSDFSFPSDNEREGKSAHGLRPEDVGQRGGSRPSPGPIRCRHRLRVSSNQHTASHLEQRGSRVKGSRDGELGTSLHTQGCTTEGDLLFAQKCEELQGFIRPLTDLLNGLKMGRFDRGLSSFQQSVAMDRIQRIVGVLRKPQMGERYLGTLLQVEGMLKTWFPRIAAQKSSLGGSRHQISKLNTVEISLSMRLSALPVR", "length": 222, "header": "tr|A0A9J7H826-1|A0A9J7H826_CRIGR Computationally mapped isoform of Circadian-associated transcriptional repressor isoform X2 OS=Cricetulus griseus OX=10029 GN=Ciart PE=4 SV=1 CANONICAL=A0A061INM9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061INM9", "url": "https://www.uniprot.org/uniprotkb/A0A061INM9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A061INM9", "url": "https://www.uniprot.org/uniprotkb/A0A061INM9" } ], "pmid": "" }, { "name": "locomotor rhythm", "id": "GO:0045475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045475", "evidence": [ { "database": "UniProtKB", "id": "A0A061INM9", "url": "https://www.uniprot.org/uniprotkb/A0A061INM9" } ], "pmid": "" }, { "name": "circadian regulation of gene expression", "id": "GO:0032922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032922", "evidence": [ { "database": "UniProtKB", "id": "A0A061INM9", "url": "https://www.uniprot.org/uniprotkb/A0A061INM9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "E-box binding", "id": "GO:0070888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070888", "evidence": [ { "database": "UniProtKB", "id": "A0A061INM9", "url": "https://www.uniprot.org/uniprotkb/A0A061INM9" } ], "pmid": "" }, { "name": "RNA 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"sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061INN2-1", "uniprot_ac": "A0A061INN2", "uniprot_id": "A0A061INN2_CRIGR", "mass": { "chemical_mass": 50759.0, "monoisotopic_mass": 50759.0 }, "refseq": { "ac": "XP_027247346", "name": "RUN domain-containing protein 3B isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247346" }, "gene_names": [ { "name": "Rundc3b", "type": "recommended", "evidence": [ { "id": "A0A061INN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061INN2" } ] }, { "name": "Rundc3b", "type": "synonym", "evidence": [ { "id": "XP_027247346", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247346" } ] } ], "protein_names": [ { "name": "RUN domain-containing protein 3B", "type": "recommended", "evidence": [ { "id": "A0A061INN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061INN2/entry#names_and_taxonomy" } ] }, { "name": "RUN domain-containing protein 3B isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027247346", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247346" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027247346", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247346" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061INN2", "url": "https://www.uniprot.org/uniprotkb/A0A061INN2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rundc3b", "url": "https://www.uniprot.org/uniprotkb/A0A061INN2", "locus": {} } ], "crossref": [ { "id": "cd17700", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17700", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100752332", "url": "https://www.ncbi.nlm.nih.gov/gene/100752332", "database": "GeneID", "categories": [ "Genome 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] }, { "id": "A0A8C2LC93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LC93-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASRSLGGLGGSRCGGGAGKKSLSSRNAAVERRNLITVCRFSVKTLIDRSCFETIDDSSPEFNNFAAVLEQILSHRLKGQVTWFGYESPRSFWDYIRVACRKVSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAIDFSFCLKGEGLDGTFPAVIDYTPYLKFEQSSDSISSDEEELRTFGSSDSESSTPENVGPPLIMDENSWFNKCKRVRQKYQLTLEQKGYLEELLRLRENQLSDSVSQNKVLLQRIEDSDLAHKLEKEQLEYIIVELQDQLTVLKNNDLRSRQELTAHLTNQWPSPGAMDVNAVALDTLLYRKHNKQWYDKSYQSLDQLSAEVSLSQASLDPSHSQEDGKQDSFNFIGEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDCLASPTAEMTSPGRTPS", "length": 454, "header": "tr|A0A061INN2-1|A0A061INN2_CRIGR Isoform 1 of RUN domain-containing protein 3B OS=Cricetulus griseus OX=10029 GN=Rundc3b PE=3 SV=1 CANONICAL=A0A061INN2-1" }, "isoforms": [ { "isoform_ac": "A0A061INN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061INN2/entry#A0A061INN2-1", "sequence": { "sequence": 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"MASRSLGGLGGSRCGGGAGKKSLSSRNAAVERRNLITVCRFSVKTLIDRSCFETIDDSSPEFNNFAAVLEQILSHRLKGQVTWFGYESPRSFWDYIRVACRKVSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAIDFSFCLKGEGLDGTFPAVIDYTPYLKFEQSSDSISSDEEELRTFGSSDSESSTPENVGPPLIMDENSWFNKCKRVRQKYQLTLEQKGYLEELLRLRENQLSDSVSQNKVLLQRIEDSDLAHKLEKEQLEYIIVELQDQLKSYQSLDQLSAEVSLSQASLDPSHSQEDGKQDSFNFIGEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDCLASPTAEMTSPGRTPS", "length": 405, "header": "tr|A0A8C2LC93-1|A0A8C2LC93_CRIGR Computationally mapped isoform of RUN domain-containing protein 3B OS=Cricetulus griseus OX=10029 GN=Rundc3b PE=3 SV=1 CANONICAL=A0A061INN2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061INN2", "url": "https://www.uniprot.org/uniprotkb/A0A061INN2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061INN2", "url": "https://www.uniprot.org/uniprotkb/A0A061INN2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752332", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752332", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 116, "end_pos": 118, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061INN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061INN2" }, { "id": "PS50826", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50826" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RUN", "eco_id": "ECO_0000259", "start_pos": 56, "end_pos": 188, "start_aa": "Asp", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 116, "end_pos": 118 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061IQC5-1", "uniprot_ac": "A0A061IQC5", "uniprot_id": "A0A061IQC5_CRIGR", "mass": { "chemical_mass": 118328.0, "monoisotopic_mass": 118328.0 }, "refseq": { "ac": "XP_003499193", "name": "SURP and G-patch domain-containing protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499193" }, "gene_names": [ { "name": "Sugp2", "type": "recommended", "evidence": [ { "id": "A0A061IQC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IQC5" } ] }, { "name": "Sugp2", "type": "synonym", "evidence": [ { "id": "XP_003499193", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499193" } ] } ], "protein_names": [ { "name": "SURP and G-patch domain-containing protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003499193", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499193" }, { "id": "A0A061IQC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IQC5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613716.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003499193", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499193" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IQC5", "url": "https://www.uniprot.org/uniprotkb/A0A061IQC5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Sugp2", "url": "https://www.uniprot.org/uniprotkb/A0A061IQC5", "locus": {} } ], "crossref": [ { "id": "100754204", "url": "https://www.ncbi.nlm.nih.gov/gene/100754204", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000061", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000061", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000467", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000467", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035967", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035967", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040169", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040169", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754204", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754204", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KAKRYHI", "url": "https://omabrowser.org/oma/group/KAKRYHI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061IQC5", "url": "https://www.orthodb.org/?gene=A0A061IQC5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23340", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23340", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23340:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23340:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01585", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01585", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01805", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01805", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003499193", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499193", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061INV3", "url": "https://www.uniprot.org/uniprotkb/A0A061INV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061INV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A061INV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IQC5", "url": "https://www.uniprot.org/uniprotkb/A0A061IQC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IQC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IQC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F965", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F965", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F965-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F965-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7J6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7J6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H7J6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H7J6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAARRMAQESLDTVLQEKCKRYGDSEAVGEALQLKAQDLLRTGSRARADIYEDVHGDSRYSASGPGVYSLDLGREGLRGDMFAGPSFRSSNQSISEDSYLRKECGRDLEATHTDSRDQSFGHRKMGHFPSQDWKLALRGTWEQDLGHPVSQESSWSQEYGFGSSVLGGLASSRRLEKENPDYDLDHRGDVNSVSRGSGQVLARGRSLNMADQEGTLLGKGDTQGLLTAKGVGKLITLKNMTTKKMPVVGRITSKPQGTNQIQKTTPSPDVTLGTSPGLDEIQLAALKMPLGLDLRALGFPRRKLGFDTMEKADVFSRFGIEIIKWAGFHTIKDDLKFSQLFQTLFELETETCAKMLASFKCSLKPEHRDFCFFTIKFLKHSALKTPRVDNEFLNMLLDKGAVKTKNCFFEIIKPFDKYIMRLQDRLLKGVTPLLMACNAYELSVKMKTLTSPLDLAVALETTNSLCRKSLALLGQTFSLASSFRQEKILEAVGLQDIAPSPASFPNFEDSTLFGREYIDHLKAWLMASGYPLQVKRAVPAEPREQKITPQPWAASTLSQAVPQRADHRVVDTIDQLVMRVIQGRLSPRERTLLLQDPAYWFLSDESSLEYKYYKLKLAESQRLNHSWPIVERRPTPAQCAVRAMLYAQAVRSLKRRLLPWQRRRLLRSQGPRAMKTKRAATAQHISLSSATRQRHHGRQAVGSLQVKPPPRDSSDAAQDCLPESAKPHPQPCSPGALGTSRPIEDDSEVLLASSPCPSADVDLKTMETAEKLARLVAQVGPEIEQFSIESSTDNPDLWFLHDQSSSAFKFYREKVLELCPSISFQSTGEAGDSEQSPTAHKEGEGEPEEGRPQQEATLEGPEVLPEEEEDDVEVEEDEGREETCTLRPQAGAAKCPGSEGSSPTDSIPGEGSREDQAGTPGLSQASSGSCFPRKRISSKSLKVGMIPAPKRVCLIQESKVHEPVRIAYDRPRGRPIAKKKKPKDLEFAQQKLTEKNLGFQMLQKMGWKEGHGLGSLGKGIREPVSVGTLSEGEGLGADGPEQKEDTFDVFRQRMMQMYRHKRASK", "length": 1065, "header": "tr|A0A061IQC5-1|A0A061IQC5_CRIGR Isoform 1 of SURP and G-patch domain-containing protein 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Sugp2 PE=4 SV=1 CANONICAL=A0A061IQC5-1" }, "isoforms": [ { "isoform_ac": "A0A061INV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IQC5/entry#A0A061INV3-1", "sequence": { "sequence": "MAARRMAQESLDTVLQEKCKRYGDSEAVGEALQLKAQDLLRTGSRARADIYEDVHGDSRYSASGPGVYSLDLGREGLRGDMFAGPSFRSSNQSISEDSYLRKECGRDLEATHTDSRDQSFGHRKMGHFPSQDWKLALRGTWEQDLGHPVSQESSWSQEYGFGSSVLGGLASSRRLEKENPDYDLDHRGDVNSVSRGSGQVLARGRSLNMADQEGTLLGKGDTQGLLTAKGVGKLITLKNMTTKKMPVVGRITSKPQGTNQIQKTTPSPDVTLGTSPGLDEIQLAALKMPLGLDLRALGFPRRKLGFDTMEKADVFSRFGIEIIKWAGFHTIKDDLKFSQLFQTLFELETETCAKMLASFKCSLKPEHRDFCFFTIKFLKHSALKTPRVDNEFLNMLLDKGAVKTKNCFFEIIKPFDKYIMRLQDRLLKGVTPLLMACNAYELSVKMKTLTSPLDLAVALETTNSLCRKSLALLGQTFSLASSFRQEKILEAVGLQDIAPSPASFPNFEDSTLFGREYIDHLKAWLMASGYPLQVKRAVPAEPREQKITPQPWAASTLSQVPQRADHRVVDTIDQLVMRVIQGRLSPRERTLLLQDPAYWFLSDESSLEYKYYKLKLAESQRLNHSWPIVERRPTPAQCAVRAMLYAQAVRSLKRRLLPWQRRRLLRSQGPRAMKTKRAATAQHISLSSATRQRHHGRQAVGSLQVKPPPRDSSDAAQDCLPESAKPHPQPCSPGALGTSRPIEDDSEVLLASSPCPSADVDLKTMETAEKLARLVAQVGPEIEQFSIESSTDNPDLWFLHDQSSSAFKFYREKVLELCPSISFQSTGEAGDSEQSPTAHKEGEGEPEEGRPQQEATLEGPEVLPEEEEDDVEVEEDEGREETCTLRPQAGAAKCPGSEGSSPTDSIPGEGSREDQAGTPGLSQASSGSCFPRKRISSKSLKVGMIPAPKRVCLIQESKVHEPVRIAYDRPRGRPIAKKKKPKDLEFAQQKLTEKNLGFQMLQKMGWKEGHGLGSLGKGIREPVSVGTLSEGEGLGADGPEQKEDTFDVFRQRMMQMYRHKRASK", "length": 1064, "header": "tr|A0A061INV3-1|A0A061IQC5_CRIGR Computationally mapped isoform of SURP and G-patch domain-containing protein 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Sugp2 PE=4 SV=1 CANONICAL=A0A061IQC5-1" }, "locus": {} }, { "isoform_ac": "A0A061IQC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IQC5/entry#A0A061IQC5-1", "sequence": { "sequence": "MAARRMAQESLDTVLQEKCKRYGDSEAVGEALQLKAQDLLRTGSRARADIYEDVHGDSRYSASGPGVYSLDLGREGLRGDMFAGPSFRSSNQSISEDSYLRKECGRDLEATHTDSRDQSFGHRKMGHFPSQDWKLALRGTWEQDLGHPVSQESSWSQEYGFGSSVLGGLASSRRLEKENPDYDLDHRGDVNSVSRGSGQVLARGRSLNMADQEGTLLGKGDTQGLLTAKGVGKLITLKNMTTKKMPVVGRITSKPQGTNQIQKTTPSPDVTLGTSPGLDEIQLAALKMPLGLDLRALGFPRRKLGFDTMEKADVFSRFGIEIIKWAGFHTIKDDLKFSQLFQTLFELETETCAKMLASFKCSLKPEHRDFCFFTIKFLKHSALKTPRVDNEFLNMLLDKGAVKTKNCFFEIIKPFDKYIMRLQDRLLKGVTPLLMACNAYELSVKMKTLTSPLDLAVALETTNSLCRKSLALLGQTFSLASSFRQEKILEAVGLQDIAPSPASFPNFEDSTLFGREYIDHLKAWLMASGYPLQVKRAVPAEPREQKITPQPWAASTLSQAVPQRADHRVVDTIDQLVMRVIQGRLSPRERTLLLQDPAYWFLSDESSLEYKYYKLKLAESQRLNHSWPIVERRPTPAQCAVRAMLYAQAVRSLKRRLLPWQRRRLLRSQGPRAMKTKRAATAQHISLSSATRQRHHGRQAVGSLQVKPPPRDSSDAAQDCLPESAKPHPQPCSPGALGTSRPIEDDSEVLLASSPCPSADVDLKTMETAEKLARLVAQVGPEIEQFSIESSTDNPDLWFLHDQSSSAFKFYREKVLELCPSISFQSTGEAGDSEQSPTAHKEGEGEPEEGRPQQEATLEGPEVLPEEEEDDVEVEEDEGREETCTLRPQAGAAKCPGSEGSSPTDSIPGEGSREDQAGTPGLSQASSGSCFPRKRISSKSLKVGMIPAPKRVCLIQESKVHEPVRIAYDRPRGRPIAKKKKPKDLEFAQQKLTEKNLGFQMLQKMGWKEGHGLGSLGKGIREPVSVGTLSEGEGLGADGPEQKEDTFDVFRQRMMQMYRHKRASK", "length": 1065, "header": "tr|A0A061IQC5-1|A0A061IQC5_CRIGR Isoform 1 of SURP and G-patch domain-containing protein 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Sugp2 PE=4 SV=1 CANONICAL=A0A061IQC5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F965-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IQC5/entry#A0A9J7F965-1", "sequence": { "sequence": "MAARRMAQESLDTVLQEKCKRYGDSEAVGEALQLKAQDLLRTGSRARADIYEDVHGDSRYSASGPGVYSLDLGREGLRGDMFAGPSFRSSNQSISEDSYLRKECGRDLEATHTDSRDQSFGHRKMGHFPSQDWKLALRGTWEQDLGHPVSQESSWSQEYGFGSSVLGGLASSRRLEKENPDYDLDHRGDVNSVSRGSGQVLARGRSLNMADQEGTLLGKGDTQGLLTAKGVGKLITLKNMTTKKMPVVGRITSKPQGTNQIQKTTPSPDVTLGTSPGLDEIQLAALKMPLGLDLRALGFPRRKLGFDTMEKADVFSRFGIEIIKWAGFHTIKDDLKFSQLFQTLFELETETCAKMLASFKCSLKPEHRDFCFFTIKFLKHSALKTPRVDNEFLNMLLDKGAVKTKNCFFEIIKPFDKYIMRLQDRLLKGVTPLLMACNAYELSVKMKTLTSPLDLAVALETTNSLCRKSLALLGQTFSLASSFRQEKILEAVGLQDIAPSPASFPNFEDSTLFGREYIDHLKAWLMASGYPLQVKRAVPAEPREQKITPQPWAASTLSQAVPQRADHRVVDTIDQLVMRVIQGRLSPRERTLLLQDPAYWFLSDESSLEYKYYKLKLAESQRLNHSWPIVERRPTPAQCAVRAMLYAQAVRSLKRRLLPWQRRRLLRSQGPRAMKTKRAATAQHISLSSATRQRHHGRQAVGSLQVKPPPRDSSDAAQDCLPESAKPHPQPCSPGALGTSRPIEDDSEVLLASSPCPSADVDLKTMETAEKLARLVAQVGPEIEQFSIESSTDNPDLWFLHDQSSSAFKFYREKVLELCPSISFQSTGEAGDSEQSPTAHKEGEGEPEEGRPQQEATLEGPEVLPEEEEDDVEVEEDEGREETCTLRPQAGAAKCPGSEGSSPTDSIPGEGSREDQAGTPGLSQASSGSCFPRKRISSKSLKVGMIPAPKRVCLIQESKVHEPVRIAYDRPRGRPIAKKKAQHRAAACHPTARCPF", "length": 996, "header": "tr|A0A9J7F965-1|A0A9J7F965_CRIGR Computationally mapped isoform of SURP and G-patch domain-containing protein 2 isoform X4 OS=Cricetulus griseus OX=10029 GN=Sugp2 PE=4 SV=1 CANONICAL=A0A061IQC5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H7J6-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IQC5/entry#A0A9J7H7J6-1", "sequence": { "sequence": "MAARRMAQESLDTVLQEKCKRYGDSEAVGEALQLKAQDLLRTGSRARADIYEDVHGDSRYSASGPGVYSLDLGREGLRGDMFAGPSFRSSNQSISEDSYLRKECGRDLEATHTDSRDQSFGHRKMGHFPSQDWKLALRGTWEQDLGHPVSQESSWSQEYGFGSSVLGGLASSRRLEKENPDYDLDHRGDVNSVSRGSGQVLARGRSLNMADQEGTLLGKGDTQGLLTAKGVGKLITLKNMTTKKMPVVGRITSKPQGTNQIQKTTPSPDVTLGTSPGLDEIQLAALKMPLGLDLRALGFPRRKLGFDTMEKADVFSRFGIEIIKWAGFHTIKDDLKFSQLFQTLFELETETCAKMLASFKCSLKPEHRDFCFFTIKFLKHSALKTPRVDNEFLNMLLDKGAVKTKNCFFEIIKPFDKYIMRLQDRLLKGVTPLLMACNAYELSVKMKTLTSPLDLAVALETTNSLCRKSLALLGQTFSLASSFRQEKILEAVGLQDIAPSPASFPNFEDSTLFGREYIDHLKAWLMASGYPLQVKRAVPAEPREQKITPQPWAASTLSQAVPQRADHRVVDTIDQLVMRVIQGRLSPRERTLLLQDPAYWFLSDESSLEYKYYKLKLAESQRLNHSWPIVERRPTPAQCAVRAMLYAQAVRSLKRRLLPWQRRRLLRSQGPRAMKTKRAATAQHISLSSATRQRHHGRQAVGSLQVKPPPRDSSDAAQDCLPESAKPHPQPCSPGALGTSRPIEDDSEVLLASSPCPSADVDLKTMETAEKLARLVAQVGPEIEQFSIESSTDNPDLWFLHDQSSSAFKFYREKVLELCPSISFQSTGEAGDSEQSPTAHKEGEGEPEEGRPQQEATLEGPEVLPEEEEDDVEVEEDEGREETCTLRPQAGAAKCPGSEGSSPTDSIPGEGSREDQAGTPGLSQASSGSCFPRKRISSKSLKVGMIPAPKRVCLIQESKETQGPGVCPAEADRKEPRLPDVAEDGLEGRPRPGLPREGHPRACQRGDTLRRRGPGG", "length": 1016, "header": "tr|A0A9J7H7J6-1|A0A9J7H7J6_CRIGR Computationally mapped isoform of SURP and G-patch domain-containing protein 2 isoform X3 OS=Cricetulus griseus OX=10029 GN=Sugp2 PE=4 SV=1 CANONICAL=A0A061IQC5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 635, "start_aa": "Thr", "end_pos": 635, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr635", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061INV3", "url": "https://www.uniprot.org/uniprotkb/A0A061INV3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061INV3", "url": "https://www.uniprot.org/uniprotkb/A0A061INV3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754204", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754204", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AX25-1", "protein_name": "SURP and G-patch domain containing 2", "gene_name": "SUGP2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATRRIAQETFDAVLQEKAKRYHMDPSGEAVGEALQFKAQDLLRTVPRARADMFDDIHSDSRYTLGGSIAHPRDTGREGLRSDVFPGPSFRSSNPSVSEDSYFRKECGRDLEFSHTDSRDQVFGHRKLGHFRSQDWKFALRGSWEQDFGHSVSQESSWSQEYSFGPSALLGDFGSSRLIEKECLEKESRDYDVDHPGEADSVLRGSSQVQGRGRGLNIVDQEGALLGKGETQGLLTPKAGVGKLVTLRSVSTKKVPTVSRITPKTQGTNQIQKTTPSSDVTLGTNPGTEDVQFPTQKIPLGLNLKDIRLPRRKMSFDLIDKSDVFSRFGIEIIKWAGFHTIKDDVKFSQLFQTLFELETETCAKMLASFKCSLKPEHRDFCFFTIKFLKHSALKTPRVDNEFLNMLLDKGAVKTKNCFFEIIKPFDKYIMRLQDRLLKSVTPLLMACNAYELSVKMKTLSNPLDLAVALETTNSLCRKSLALLGQTFSLASSFRQEKILEAVGLQDIAPSPAAFPNFEDSTLFGREYIDHLKAWLVSSGCPLQVKKAEPEPARDEEKTVPPAKPEIQAKAPSGLSDEVPQRADHKVVDIIDQLVSRVVGGSLSPKERALLKEDPAYWFLSDDSSLEYKYYKLKLAEMQRMSQTMPGADQKPMAAECAVRAMLYARAVRSLKKRLLPGRRRGLLRAQGLRGWKVRKATTGTQTLLSSGTRLKHHGRQAPGSLQGKLPQPDGNAAAKDCLPDPAGPSPQDPSPEASGPSPKPAGVDVPEAPQSSSPCPSSDVDTKTMETAEKLAKFVAQVGPEIEQFSIENSTDNPDLWFLHDQNSSAFKFYRKKVFELCPSICFTSSPLNLRASESADSQESPLEPMEGEGEFEDEPPQHEAELESPEVIPEEDEEDEEEEEDEEGDEEAPTPGGASRLAGESTKSEGSEGSSPADGLLSEVAEDGSVGTPALSQASSGACFPRKRVSSKSLKVGMIPAPKRLCLIEEPKVHEPVRIAYDRPRGRPVSKKKKPKDLDFAQQKLTDKNLGFQMLQKMGWKEGHGLGSCGKGIREPVSVGTASEGEGLGADGQEHKEDTFDVFRQRMMQMYRHKRANK", "length": 1095 }, "evidence": [ { "id": "A0A061IQC5", "url": "https://omabrowser.org/oma/group/A0A061IQC5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZJH2-1", "protein_name": "SURP and G patch domain containing 2", "gene_name": "Sugp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAARRMAQESLDTVLQDKSKRYGDSEAVGEALHLKAQDLLRTGSRARADVYEDIHGDSRCSVSGSAVYSLDLGREGLRGDMFVGPSFRSSNQSVGEDSYLRKECGRDLEPAHTDSRDQSFGHRNLGHFPSQDWKLALRGSWEQDLGHSVSQESSWSQEYGFGPSLLGDLASSRRMEKESRDFDLDHPGEVDSVSRSSGQVLARGRSLNMADQEGTLIGKGDTQGLLGAKGVGKLITLKSMTTKKIPVVSRITSKPQGTNQIQKAAPSPDVTVGASPVLDEIQFAALKIPLGMDLRTLSFPRRKLGFDAIDKADVFSRFGIEIIKWAGFHTIKDDLKFSQLFQTLFELETETCAKMLASFKCSLKPEHRDFCFFTIKFLKHSALKTPRVDNEFLNMLLDKGAVKTKNCFFEIIKPFDKYIMRLQDRLLKGVTPLLMACNAYELSVKMKTLTSPLDLAVALETTNSLCKKSLALLGQTFSLASSFRQEKILEAVGLQDIAPSPAYFPNFEDSTLFGREYIDHLKAWLMASGYPLQVKRAVPPEPREQKTTAQTWAASTLSQAVPQRADHRVVDTIDQLVMRVIQGRLSPRERTLLLQDPAYWFLSDESSLEYKYYKLKLAESQRLNHSWPIVERRPTPAQCAVRAMLYAQAVRSLKRRLLPWQRRRLLRSQGPRGLKPKKATTAQQISLSSGTRLKHHGRQASGSLRVKPPPRDSSDAAQDCLPEPAKPCAQPSSPGALGPSPQPAAGDDSEALPASSRCSSANMDAKTMETAEKLARFVAQVGPEIEQFSIENSTDNPDLWFLHDQSSSAFKFYREKVLELCPSISFQSTGEAGDSVQSPTAGKEGKGEPEEGRPEQEAALEGSEVLPEEEEEDEEESEEDEGGEETCTLTPQTGAAKCPGSEGSSPTESIPGEGAREDQAGTPGLSQASSGSCFPRKRISSKSLKVGMIPAPKRVCLIQESKVHEPVRIAYDRPRGRPIAKKKKPKDLEFSQQKLTDKNVGFQMLQKMGWKEGHGLGSLGKGIREPVSVGTLSEGEGLGADGPEQKEDTFDVFRQRMMQMYRHKRASK", "length": 1068 }, "evidence": [ { "id": "A0A061IQC5", "url": "https://omabrowser.org/oma/group/A0A061IQC5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BE55-1", "protein_name": "SURP and G-patch domain containing 2", "gene_name": "SUGP2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAARRIAQETFDAVLQEKANRYMDPSGEAVGETLQFKAQDLLRTVPRARADMFDDIHSDSRYTLGTSVTHPRDTGREGLRGDIFPGPSFRSNNPSVSEDSYFRKECGRDLEFSHPNSRDQVFGHRKLGHFRSQDWKFALHGSWEQDFAHSVSQESSWSQEYSFGPSALLGNFGSSRLIEKECLEKESHDYDGDRPGEADSVLRGSSQAQGRGRGLNLADQEGAVLGKGETQGLLTSKVGVGKLVMLRNVSTKKVPTMSRITPKTQGTNQIQKTTSSPDVTLATNPGTEVQFPTRKVPLGLDLKDVRLPRRKMSFDIIDKSDVFSRFGIEIIKWAGFHTIKDDVKFSQLFQTLFELETETCAKMLASFKCSLKPEHRDFCFFTIKFLKHSALKTPRVDNEFLNMLLDKGAVKTKNCFFEIIKPFDKYIMRLQDRLLKSVTPLLMACNAYELSVKMKTLTNPLDLAIALETTNSLCRKSLALLGQTFSLASSFRQEKILEAVGLQDIAPSPAAFPNFEDSTLFGREYIDHLKAWLVSSGCPLQVKKTESEPTRDEEKAVPSTKPEIQAQALSGLSDGPMWSRVFLREDPLCVPEVPQRADHKVVDIIDQLVARVIGGSLSPKERALLQEDPAYWFLSDDSSLEYKYYKLKLAEMQRMSQTLPGADQKPTAAECAVRAMLYARAVRSLKRRLLPGRRRGHLRAQGLRGWKVRRATTGTQTLLSSGTRLKHHGRQAPGSLQGKSPQPDRSDAAKDCPPELAGPSPRDPSPEASGPSPKPGGLDVSEAPQTSSPCPSIDVDTKTMETAEKLAKFVAQVGPEIEQFSIENSIDNPDLWFLHDQNSSAFKFYRKKVFELCPSICFTSSPLTLHASESADSQESPLEPMEGEGEFEDEPSQHEAELESPEVMPEEEEEEEEDEEDEEEDEEGGEEASPPGGVSRPAEGSKSEGSEGSPPADGLLSEVAEDSPAGGPALSQASSGACFPRKRISSKSLKVGMIPAPKRLCLIQEPKVHEPVRIAYDRPRGRPVSKKKKPKDFDFAQQKLTDKNLGFQMLQKMGWKEGHGLGSCGKGIREPVSVGSASEGEGLGADGQEHKEDTFDVFRQRMMQMYRHRRASK", "length": 1113 }, "evidence": [ { "id": "A0A061IQC5", "url": "https://omabrowser.org/oma/group/A0A061IQC5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8CH09-1", "protein_name": "SURP and G-patch domain-containing protein 2", "gene_name": "Sugp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAARRMAQESLDSVLQEKSKRYGDSEAVGEALHLKAQDLLRTGSRARADVYEDIHGDSRYSASGSGVYSLDMGREGLRGDMFVGPSFRSSNQSVGEDSYLRKECGRDLEPAHTDSRDQSFGHRNLGHFPSQDWKLALRGSWEQDLGHSVSQESSWSQEYGFGPSLLGDLASSRRMEKESRDYDLDHPGEVDSVSRSSGQVLTRGRSLNIADQEGTLLGKGDTQGLLGAKGVGKLITLKSMTTKKIPVASRITSKPQGTNQIQKPTPSPDVTIGTSPVLDEIQFAALKIPLGLDLRTLGLPRRKMGFDAIDKADVFSRFGIEIIKWAGFHTIKDDLKFSQLFQTLFELETETCAKMLASFKCSLKPEHRDFCFFTIKFLKHSALKTPRVDNEFLNMLLDKGAVKTKNCFFEIIKPFDKSIMRLQDRLLKGVTPLLMACNAYELSVKMKTLTSPLDLAMALETTNSLCRKSLALLGQTFSLASSFRQEKILEAVGLQDIAPSPAYFPNFEDSTLFGREYIDHLKAWLMASGYPLQLKRAVPPESREQKTTAQTWASSTLSQAVPQRADHRVVDTIDQLVMRVIQGRLSPRERTLLLQDPAYWFLSDESSLEYKYYKLKLAESQRLNHSWPIVERRPTPAQCAVRAMLYAQAVRSLKRRLLPWQRRRLIRSQGPRGLKAKKATTAQQTSLSSGTRQKHHGRQASGSLRVKPPPRDSSDAAQDCLSEPAKPCPQPSSPGALGPSPRPTGADDSEALPASSRCPSANMDAKTMETAEKLARFVAQVGPEIEQFSIENSTDNPDLWFLHDQSSSAFKFYREKVLELCPSISFQSTGEAGDSVQSPTAGKEGKGEPQEGHPEQEASLEGTEVLPEEEEEDEEESEDEGGEETSTLRPQAGAAKCPGSEGSSPTDSIPGEGSREDQASTPGLSQASSGSCFPRKRISSKSLKVGMIPAPKRVCLIQESKVHEPVRIAYDRPRGRPIAKKKKPKDMEFSQQKLTDKNVGFQMLQKMGWKEGHGLGSLGKGIREPVSVGALSEGEGLGADGPEQKEDTFDVFRQRMMQMYRHKRASK", "length": 1067 }, "evidence": [ { "id": "A0A061IQC5", "url": "https://omabrowser.org/oma/group/A0A061IQC5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IX01-1", "protein_name": "SURP and G-patch domain-containing protein 2", "gene_name": "SUGP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAARRITQETFDAVLQEKAKRYHMDASGEAVSETLQFKAQDLLRAVPRSRAEMYDDVHSDGRYSLSGSVAHSRDAGREGLRSDVFPGPSFRSSNPSISDDSYFRKECGRDLEFSHSDSRDQVIGHRKLGHFRSQDWKFALRGSWEQDFGHPVSQESSWSQEYSFGPSAVLGDFGSSRLIEKECLEKESRDYDVDHPGEADSVLRGGSQVQARGRALNIVDQEGSLLGKGETQGLLTAKGGVGKLVTLRNVSTKKIPTVNRITPKTQGTNQIQKNTPSPDVTLGTNPGTEDIQFPIQKIPLGLDLKNLRLPRRKMSFDIIDKSDVFSRFGIEIIKWAGFHTIKDDIKFSQLFQTLFELETETCAKMLASFKCSLKPEHRDFCFFTIKFLKHSALKTPRVDNEFLNMLLDKGAVKTKNCFFEIIKPFDKYIMRLQDRLLKSVTPLLMACNAYELSVKMKTLSNPLDLALALETTNSLCRKSLALLGQTFSLASSFRQEKILEAVGLQDIAPSPAAFPNFEDSTLFGREYIDHLKAWLVSSGCPLQVKKAEPEPMREEEKMIPPTKPEIQAKAPSSLSDAVPQRADHRVVGTIDQLVKRVIEGSLSPKERTLLKEDPAYWFLSDENSLEYKYYKLKLAEMQRMSENLRGADQKPTSADCAVRAMLYSRAVRNLKKKLLPWQRRGLLRAQGLRGWKARRATTGTQTLLSSGTRLKHHGRQAPGLSQAKPSLPDRNDAAKDCPPDPVGPSPQDPSLEASGPSPKPAGVDISEAPQTSSPCPSADIDMKTMETAEKLARFVAQVGPEIEQFSIENSTDNPDLWFLHDQNSSAFKFYRKKVFELCPSICFTSSPHNLHTGGGDTTGSQESPVDLMEGEAEFEDEPPPREAELESPEVMPEEEDEDDEDGGEEAPAPGGAGKSEGSTPADGLPGEAAEDDLAGAPALSQASSGTCFPRKRISSKSLKVGMIPAPKRVCLIQEPKVHEPVRIAYDRPRGRPMSKKKKPKDLDFAQQKLTDKNLGFQMLQKMGWKEGHGLGSLGKGIREPVSVGTPSEGEGLGADGQEHKEDTFDVFRQRMMQMYRHKRANK", "length": 1082 }, "evidence": [ { "id": "A0A061IQC5", "url": "https://omabrowser.org/oma/group/A0A061IQC5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A061IQC5", "url": "https://www.uniprot.org/uniprotkb/A0A061IQC5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A061IQC5", "url": "https://www.uniprot.org/uniprotkb/A0A061IQC5" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A061IQC5", "url": "https://www.uniprot.org/uniprotkb/A0A061IQC5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "A0A061IQC5", "url": "https://www.uniprot.org/uniprotkb/A0A061IQC5" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "A0A061IQC5", "url": "https://www.uniprot.org/uniprotkb/A0A061IQC5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 239, "end_pos": 241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 624, "end_pos": 626, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061IQC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IQC5" }, { "id": "PS50174", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50174" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-patch", "eco_id": "ECO_0000259", "start_pos": 994, "end_pos": 1040, "start_aa": "Glu", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A061IQC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IQC5" }, { "id": "PS50128", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50128" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SURP motif", "eco_id": "ECO_0000259", "start_pos": 768, "end_pos": 811, "start_aa": "Thr", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 635 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 239, "end_pos": 241 }, { "start_pos": 624, "end_pos": 626 }, { "start_pos": 91, "end_pos": 93 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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automated computational analysis. 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Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614628.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003509074", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509074" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IPC2", "url": "https://www.uniprot.org/uniprotkb/A0A061IPC2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "CUNH5orf52", "url": "https://www.uniprot.org/uniprotkb/A0A061IPC2", "locus": {} } ], "crossref": [ { "id": "100760617", "url": "https://www.ncbi.nlm.nih.gov/gene/100760617", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR038935", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038935", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760617", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760617", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RKMSHLY", "url": "https://omabrowser.org/oma/group/RKMSHLY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061IPC2", "url": "https://www.orthodb.org/?gene=A0A061IPC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35666", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35666", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35666:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35666:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF17666", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17666", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003509074", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509074", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IPC2", "url": "https://www.uniprot.org/uniprotkb/A0A061IPC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IPC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IPC2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFGLATIPESLSIEEDSSSQPRKTFVKWDLGSKLESVAKETTTPGPDFRRERIDSPPDLGERVLPQIHFLRPRPAIPMFLFSVLNSSDANVKKLLPKSHLSRVIIRDNLNAQRMYEMEMKASDKTKRKMSNLYDYLKKKFVADQLRKMLRWRRESLSTQRYLDKQRLFRHSA", "length": 173, "header": "tr|A0A061IPC2-1|A0A061IPC2_CRIGR Isoform 1 of Uncharacterized protein C5orf52 homolog OS=Cricetulus griseus OX=10029 GN=CUNH5orf52 PE=4 SV=1 CANONICAL=A0A061IPC2-1" }, "isoforms": [ { "isoform_ac": "A0A061IPC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IPC2/entry#A0A061IPC2-1", "sequence": { "sequence": "MAFGLATIPESLSIEEDSSSQPRKTFVKWDLGSKLESVAKETTTPGPDFRRERIDSPPDLGERVLPQIHFLRPRPAIPMFLFSVLNSSDANVKKLLPKSHLSRVIIRDNLNAQRMYEMEMKASDKTKRKMSNLYDYLKKKFVADQLRKMLRWRRESLSTQRYLDKQRLFRHSA", "length": 173, "header": "tr|A0A061IPC2-1|A0A061IPC2_CRIGR Isoform 1 of Uncharacterized protein C5orf52 homolog OS=Cricetulus griseus OX=10029 GN=CUNH5orf52 PE=4 SV=1 CANONICAL=A0A061IPC2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IPC2", "url": "https://www.uniprot.org/uniprotkb/A0A061IPC2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IPC2", "url": "https://www.uniprot.org/uniprotkb/A0A061IPC2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760617", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760617", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A6NGY3-1", "protein_name": "Uncharacterized protein C5orf52", "gene_name": "C5orf52", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTQPTRPSVTCDQGSSTIGGTAAQATTSSSATSGSNYQRDRLGRRPEIGVGGQPQICFPRPRSAQQPVLFSLMNSSEAAMKKTLPKSHLSRVIIHDNRITQRIYEMEVSALEKTKKKISHYYEHLKKKFMTEQLRKLGRWREESVNSNRYLTFGIPPPV", "length": 159 }, "evidence": [ { "id": "A0A061IPC2", "url": "https://omabrowser.org/oma/group/A0A061IPC2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "E1BKK8-1", "protein_name": "Chromosome 17 C5orf52 homolog", "gene_name": "C17H5orf52", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDPEEAPIPELLAKAGDENSAVGQQLRPSVTWNLDSPVAGAVAPQATSSSGTYPASAFFRHSRLSNRRDTHVGSQPKICFLRPRTAQPLVLFSLMNSSEAAVKKFLPKSHLSRVIIRDNLSAQRIYEMEIRAADKTKKKMNHLYDHLKKKFMTDQLRKLGRWRRESTNIRQYLDSIRGNKVPLKPQPNRKNQPP", "length": 194 }, "evidence": [ { "id": "A0A061IPC2", "url": "https://omabrowser.org/oma/group/A0A061IPC2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 86, "end_pos": 88, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 86, "end_pos": 88 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061IPF1-1", "uniprot_ac": "A0A061IPF1", "uniprot_id": "A0A061IPF1_CRIGR", "mass": { "chemical_mass": 18806.0, "monoisotopic_mass": 18806.0 }, "refseq": { "ac": "XP_003504793", "name": "28S ribosomal protein S24, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504793" }, "gene_names": [ { "name": "Mrps24", "type": "recommended", "evidence": [ { "id": "A0A061IPF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IPF1" } ] }, { "name": "Mrps24", "type": "synonym", "evidence": [ { "id": "XP_003504793", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504793" } ] } ], "protein_names": [ { "name": "28S ribosomal protein S24, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_003504793", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504793" }, { "id": "A0A061IPF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IPF1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614085.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003504793", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504793" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IPF1", "url": "https://www.uniprot.org/uniprotkb/A0A061IPF1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mrps24", "url": "https://www.uniprot.org/uniprotkb/A0A061IPF1", "locus": {} } ], "crossref": [ { "id": "100761173", "url": "https://www.ncbi.nlm.nih.gov/gene/100761173", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026146", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026146", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761173", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761173", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FLQGYTE", "url": "https://omabrowser.org/oma/group/FLQGYTE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061IPF1", "url": "https://www.orthodb.org/?gene=A0A061IPF1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21244", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21244", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21244:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21244:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14955", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14955", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003504793", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504793", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IPF1", "url": "https://www.uniprot.org/uniprotkb/A0A061IPF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IPF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IPF1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALSASVRRLGVGMLSCSRELPCAWRALHTSAVCAKNRAARVRVAKGDKPVSYEEAHAPHHIAHRKGWLSLHTGNLDGEDHAAERTLEDVFLRKFMLGTFPGCLADQIVLKRRANQVDICAVVLRQLPAHKFYFLVGYSETLLSHFYKCPVRLHLQTVPSKVVYKYI", "length": 167, "header": "tr|A0A061IPF1-1|A0A061IPF1_CRIGR Isoform 1 of 28S ribosomal protein S24, mitochondrial OS=Cricetulus griseus OX=10029 GN=Mrps24 PE=3 SV=1 CANONICAL=A0A061IPF1-1" }, "isoforms": [ { "isoform_ac": "A0A061IPF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IPF1/entry#A0A061IPF1-1", "sequence": { "sequence": "MALSASVRRLGVGMLSCSRELPCAWRALHTSAVCAKNRAARVRVAKGDKPVSYEEAHAPHHIAHRKGWLSLHTGNLDGEDHAAERTLEDVFLRKFMLGTFPGCLADQIVLKRRANQVDICAVVLRQLPAHKFYFLVGYSETLLSHFYKCPVRLHLQTVPSKVVYKYI", "length": 167, "header": "tr|A0A061IPF1-1|A0A061IPF1_CRIGR Isoform 1 of 28S ribosomal protein S24, mitochondrial OS=Cricetulus griseus OX=10029 GN=Mrps24 PE=3 SV=1 CANONICAL=A0A061IPF1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IPF1", "url": "https://www.uniprot.org/uniprotkb/A0A061IPF1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IPF1", "url": "https://www.uniprot.org/uniprotkb/A0A061IPF1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761173", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761173", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ANU4-1", "protein_name": "Mitochondrial ribosomal protein S24", "gene_name": "MRPS24", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVASVCGGGLRPLVLSWSRELPCAWRALHISAVCAKNRAARVRVSKGDKPVTYEEAHAPHYIAHRKGWLSLHTGNLDGEDHAAERTVEDVFLRKFMLGTFPGCLADQLVLKRRANQLEICALVLRQLPPHKFYFLVGYSETLLSHFYKCPVHLHLQTVPSKVVYKYI", "length": 167 }, "evidence": [ { "id": "A0A061IPF1", "url": "https://omabrowser.org/oma/group/A0A061IPF1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q2M2T7-1", "protein_name": "Small ribosomal subunit protein uS3m", "gene_name": "MRPS24", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVALYCGGGLRPLMLSWSRDLPCIWRALHTSAVCFKNRAARVRVGKGNKPVTYEEAHAPHYIAHRKGWLSLHTGNLDGEDHAAERTVEDVFLRKFMLGTFPGCLADQLILKRRANQVEICALVLRQLPAHKFYFLVGYSETLLSHFYKCPVRLHLQTVPSKVVYKYI", "length": 167 }, "evidence": [ { "id": "A0A061IPF1", "url": "https://omabrowser.org/oma/group/A0A061IPF1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q502C1-1", "protein_name": "Small ribosomal subunit protein uS3m", "gene_name": "mrps24", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAASLIRQTKLLSVFSSAGCFRSIHSTAACLKNRAARIRVGKGDRPLTYEQAHHPHHISHRKGWLSQHTGNLHAEGGAAERVLEDVFIRRFIFGTFHSCLADELVIKRRGNVLIICAVMIQKLLPSKFYFLLGYTEELLSHFYKCPVKMELQLVDEKVVYKYL", "length": 163 }, "evidence": [ { "id": "A0A061IPF1", "url": "https://omabrowser.org/oma/group/A0A061IPF1/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q96EL2-1", "protein_name": "Small ribosomal subunit protein uS3m", "gene_name": "MRPS24", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASVCSGLLGPRVLSWSRELPCAWRALHTSPVCAKNRAARVRVSKGDKPVTYEEAHAPHYIAHRKGWLSLHTGNLDGEDHAAERTVEDVFLRKFMWGTFPGCLADQLVLKRRGNQLEICAVVLRQLSPHKYYFLVGYSETLLSYFYKCPVRLHLQTVPSKVVYKYL", "length": 167 }, "evidence": [ { "id": "A0A061IPF1", "url": "https://omabrowser.org/oma/group/A0A061IPF1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CQV5-1", "protein_name": "Small ribosomal subunit protein uS3m", "gene_name": "Mrps24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAWSASVRGLGQRVLACSRELPGAWRTLHTSAVCAKNRAARVRVAKGNKPVSYEEAHAPHYIAHRKGWLSLHTGNLDGEDHAAERTLEDVFLRKFMMGTFPGCLADQIVLKRRANQVDICALVLRQLPAHKFYFLVGYSETLLSHFYKCPVRLHLQTVPSKVVYKYI", "length": 167 }, "evidence": [ { "id": "A0A061IPF1", "url": "https://omabrowser.org/oma/group/A0A061IPF1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VCC3-1", "protein_name": "Small ribosomal subunit protein uS3m", "gene_name": "mRpS24", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNFLKKLLPQVATEVQQLSRSGFHTSSVCCRVQSGRYRITTKRNRPLTYEMANPPHFIGHRKSWNSWNTSTMKDALRPSQTAIEDVFIRKFVTGTWHALVCSEVIIKRQHNTIRIAALIRQAITPRKMYFLIGYTEELLSYWMQCPVTLELQTVGDKKDVVFKYI", "length": 165 }, "evidence": [ { "id": "A0A061IPF1", "url": "https://omabrowser.org/oma/group/A0A061IPF1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A061IPF1", "url": "https://www.uniprot.org/uniprotkb/A0A061IPF1" } ], "pmid": "" }, { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "A0A061IPF1", "url": "https://www.uniprot.org/uniprotkb/A0A061IPF1" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A061IPF1", "url": "https://www.uniprot.org/uniprotkb/A0A061IPF1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A061IPF1", "url": "https://www.uniprot.org/uniprotkb/A0A061IPF1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061IQC9-1", "uniprot_ac": "A0A061IQC9", "uniprot_id": "A0A061IQC9_CRIGR", "mass": { "chemical_mass": 101596.0, "monoisotopic_mass": 101596.0 }, "refseq": { "ac": "XP_027248030", "name": "methyl-CpG-binding domain protein 6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248030" }, "gene_names": [ { "name": "Mbd6", "type": "recommended", "evidence": [ { "id": "A0A061IQC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IQC9" } ] }, { "name": "Mbd6", "type": "synonym", "evidence": [ { "id": "XP_027248030", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248030" } ] } ], "protein_names": [ { "name": "Methyl-CpG-binding domain protein 6 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A061IQC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IQC9/entry#names_and_taxonomy" } ] }, { "name": "methyl-CpG-binding domain protein 6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027248030", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248030" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027248030", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248030" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IQC9", "url": "https://www.uniprot.org/uniprotkb/A0A061IQC9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mbd6", "url": "https://www.uniprot.org/uniprotkb/A0A061IQC9", "locus": {} } ], "crossref": [ { "id": "100757235", "url": "https://www.ncbi.nlm.nih.gov/gene/100757235", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001739", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001739", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016177", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016177", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757235", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757235", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061IQC9", "url": "https://www.orthodb.org/?gene=A0A061IQC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16112", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16112", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16112:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16112:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_027248030", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248030", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IPM5", "url": "https://www.uniprot.org/uniprotkb/A0A061IPM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IPM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IPM5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IQC9", "url": "https://www.uniprot.org/uniprotkb/A0A061IQC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IQC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IQC9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNGGNESSGADRAGGPVATSVPIGWQRCVREGAVFYISPSGTELSSLEQTRSYLLSDGTCKCGLECPLNVPKVFNFDPLAPVTPGGAGVGPASEEDMTKLCNHRRKAVAMATLYRSMETTCSHSSPGEGASPQMFHTVSPGPPSVRPPCRVPLTTPLNGGPGSLPQEPPSAPQSFPPLTGPAGLFPPPRFPDPVPSGGSSSPCFLPRGNAPSPAPPPPPAISLNAPSYNWRASLRSNLVPSDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAPPGPSGSATQPPVSSATMHLPLVLGSLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSPRPSQRRPRRPPTVLRLLEGGGPQTPRRSRPRAPAPVPQAFPLPEPSQPILPSVLSLLGLPTPDPSHSDGSFNLLGSDAHLPPPPTLSSGSPTQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSDGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLGLGQPPPSPLLSHSLFGVLAGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLSPSPSDLLPAPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLPPLLFPPLSAPPTLIALNSALLAASLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASTLGKAPSNSGRPPQLLSPLLSASLLGDLSSLTSSPGPLPSLLQPPGPLLSSQLGLQLLPGGGAPPSLSETSSPLACLLQSLQQIPPEQPDAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRGRRGGGGLRGINGETRPGRGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGGAEPKDPPLPGTHSEDLKVAPGTVRKSRRGRRRKYNPARNSSSSRQDVTLEPSPTTRAAVPLPPRARPGRPAKNKRRKLAP", "length": 1006, "header": "tr|A0A061IQC9-1|A0A061IQC9_CRIGR Isoform 1 of Methyl-CpG-binding domain protein 6 isoform X1 OS=Cricetulus griseus OX=10029 GN=Mbd6 PE=4 SV=1 CANONICAL=A0A061IQC9-1" }, "isoforms": [ { "isoform_ac": "A0A061IPM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IQC9/entry#A0A061IPM5-1", "sequence": { "sequence": "MNGGNESSGADRAGGPVATSVPIGWQRCVREGAVFYISPSGTELSSLEQTRSYLLSDGTCKCGLECPLNVPKVFNFDPLAPVTPGGAGVGPASEEDMTKLCNHRRKAVAMATLYRSMETTCSHSSPGEGASPQMFHTVSPGPPSVRPPCRVPLTTPLNGGPGSLPQEPPSAPQSFPPLTGPAGLFPPPRFPDPVPSGGSSSPCFLPRGNAPSPAPPPPPAISLNAPSYNWRASLRSNLVPSDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAPPGPSGSATQPPVSSATMHLPLVLGSLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSPRPSQRRPRRPPTVLRLLEGGGPQTPRRSRPRAPAPVPQAFPLPEPSQPILPSVLSLLGLPTPDPSHSDGSFNLLGSDAHLPPPPTLSSGSPTQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSDGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLGLGQPPPSPLLSHSLFGVLAGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLSPSPSDLLPAPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLPPLLFPPLSAPPTLIALNSALLAASLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASTLGKAPSNSGRPPQLLSPLLSASLLGDLSSLTSSPGPLPSLLQPPGPLLSSQLGLQLLPGGGAPPSLSETSSPLACLLQSLQIPPEQPDAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRGRRGGGGLRGINGETRPGRGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGGAEPKDPPLPGTHSEDLKVAPGTVRKSRRGRRRKYNPARNSSSSRQDVTLEPSPTTRAAVPLPPRARPGRPAKNKRRKLAP", "length": 1005, "header": "tr|A0A061IPM5-1|A0A061IQC9_CRIGR Computationally mapped isoform of Methyl-CpG-binding domain protein 6 isoform X1 OS=Cricetulus griseus OX=10029 GN=Mbd6 PE=4 SV=1 CANONICAL=A0A061IQC9-1" }, "locus": {} }, { "isoform_ac": "A0A061IQC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IQC9/entry#A0A061IQC9-1", "sequence": { "sequence": "MNGGNESSGADRAGGPVATSVPIGWQRCVREGAVFYISPSGTELSSLEQTRSYLLSDGTCKCGLECPLNVPKVFNFDPLAPVTPGGAGVGPASEEDMTKLCNHRRKAVAMATLYRSMETTCSHSSPGEGASPQMFHTVSPGPPSVRPPCRVPLTTPLNGGPGSLPQEPPSAPQSFPPLTGPAGLFPPPRFPDPVPSGGSSSPCFLPRGNAPSPAPPPPPAISLNAPSYNWRASLRSNLVPSDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAPPGPSGSATQPPVSSATMHLPLVLGSLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSPRPSQRRPRRPPTVLRLLEGGGPQTPRRSRPRAPAPVPQAFPLPEPSQPILPSVLSLLGLPTPDPSHSDGSFNLLGSDAHLPPPPTLSSGSPTQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSDGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLGLGQPPPSPLLSHSLFGVLAGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLSPSPSDLLPAPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLPPLLFPPLSAPPTLIALNSALLAASLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASTLGKAPSNSGRPPQLLSPLLSASLLGDLSSLTSSPGPLPSLLQPPGPLLSSQLGLQLLPGGGAPPSLSETSSPLACLLQSLQQIPPEQPDAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRGRRGGGGLRGINGETRPGRGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGGAEPKDPPLPGTHSEDLKVAPGTVRKSRRGRRRKYNPARNSSSSRQDVTLEPSPTTRAAVPLPPRARPGRPAKNKRRKLAP", "length": 1006, "header": "tr|A0A061IQC9-1|A0A061IQC9_CRIGR Isoform 1 of Methyl-CpG-binding domain protein 6 isoform X1 OS=Cricetulus griseus OX=10029 GN=Mbd6 PE=4 SV=1 CANONICAL=A0A061IQC9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 636, "start_aa": "Thr", "end_pos": 636, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr636", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 693, "start_aa": "Thr", "end_pos": 693, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr693", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 83, "start_aa": "Thr", "end_pos": 83, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr83", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IPM5", "url": "https://www.uniprot.org/uniprotkb/A0A061IPM5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IPM5", "url": "https://www.uniprot.org/uniprotkb/A0A061IPM5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757235", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757235", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A061IQC9", "url": "https://www.uniprot.org/uniprotkb/A0A061IQC9" } ], "pmid": "" }, { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A061IQC9", "url": 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003508369", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508369" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IPR6", "url": "https://www.uniprot.org/uniprotkb/A0A061IPR6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Crip3", "url": "https://www.uniprot.org/uniprotkb/A0A061IPR6", "locus": {} } ], "crossref": [ { "id": "cd09476", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09476", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100754142", "url": "https://www.ncbi.nlm.nih.gov/gene/100754142", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754142", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754142", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PRHWPKV", "url": "https://omabrowser.org/oma/group/PRHWPKV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061IPR6", "url": "https://www.orthodb.org/?gene=A0A061IPR6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46074", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46074", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46074:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46074:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003508369", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508369", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IPR6", "url": "https://www.uniprot.org/uniprotkb/A0A061IPR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IPR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IPR6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K3N4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3N4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K3N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K3N4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSWTCPRCQQPVYFAEKVSSLGKNWHRFCLKCEHCHSILSPGGHAEHNGRPYCHKPCYGALFGPRGVNIGGVGCYPYSPPAPSPASSVSLSPSNFSPPRPRAGLPQAKKSPPYTKTFTGETSMCPGCGDPVYFAEKVMSLGRNWHRPCLRCHRCRKTLTAGSHAEHDGTPYCHIPCYGYLFGPKGVNIGNVGCYIYDPVEIRSK", "length": 204, "header": "tr|A0A061IPR6-1|A0A061IPR6_CRIGR Isoform 1 of Cysteine-rich protein 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Crip3 PE=4 SV=1 CANONICAL=A0A061IPR6-1" }, "isoforms": [ { "isoform_ac": "A0A061IPR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IPR6/entry#A0A061IPR6-1", "sequence": { "sequence": "MSWTCPRCQQPVYFAEKVSSLGKNWHRFCLKCEHCHSILSPGGHAEHNGRPYCHKPCYGALFGPRGVNIGGVGCYPYSPPAPSPASSVSLSPSNFSPPRPRAGLPQAKKSPPYTKTFTGETSMCPGCGDPVYFAEKVMSLGRNWHRPCLRCHRCRKTLTAGSHAEHDGTPYCHIPCYGYLFGPKGVNIGNVGCYIYDPVEIRSK", "length": 204, "header": "tr|A0A061IPR6-1|A0A061IPR6_CRIGR Isoform 1 of Cysteine-rich protein 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Crip3 PE=4 SV=1 CANONICAL=A0A061IPR6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K3N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IPR6/entry#A0A9J7K3N4-1", "sequence": { "sequence": "MSWTCPRCQQPVYFAEKVSSLGKNWHRFCLKCEHCHSILSPGGHAEHNGRPYCHKPCYGALFGPRGPPYTKTFTGETSMCPGCGDPVYFAEKVMSLGRNWHRPCLRCHRCRKTLTAGSHAEHDGTPYCHIPCYGYLFGPKGVNIGNVGCYIYDPVEIRSK", "length": 160, "header": "tr|A0A9J7K3N4-1|A0A9J7K3N4_CRIGR Computationally mapped isoform of Cysteine-rich protein 3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Crip3 PE=4 SV=1 CANONICAL=A0A061IPR6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IPR6", "url": "https://www.uniprot.org/uniprotkb/A0A061IPR6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IPR6", "url": "https://www.uniprot.org/uniprotkb/A0A061IPR6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754142", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754142", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZNQ0-1", "protein_name": "Cysteine-rich protein 3", "gene_name": "Crip3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSWTCPRCQQPVYFAEKVSSVGKHWHRFCLKCERCHSILSPGGHAEHNGRPYCHKPCYGALFGPRGVNIGGVGCYLYNPPSPPPASSISLSPSNFSPPRPRTGLPRAKKSPPYLKTFTGETSLCPGCGDPVYFAEKVMSLGRNWHRPCLRCQRCRKTLTAGSHAEHDGMPYCHIPCYGYLFGPKGVNIGDVGCYIYDPVDIRPK", "length": 204 }, "evidence": [ { "id": "A0A061IPR6", "url": "https://omabrowser.org/oma/group/A0A061IPR6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BFL4-1", "protein_name": "Cysteine rich protein 3", "gene_name": "CRIP3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSWTCPRCQQPVFFAEKVSSLGKNWHPFCLKCEHCHSVLSPGGHAEHNGRPYCHKPCYGALFGPRGVNIGGVGSYLYKPPTPTPASITHLSPSSFSPPRPRTGLPQGKKSPPHMKTFTGETSLCPGCEEPVYFAETVMSLGRNWHRPCLRCQRCRKTLTAGSHAEHDGAPYCHIPCYGYLFGPKGVNIGDVGCYIYDPVEIKSK", "length": 204 }, "evidence": [ { "id": "A0A061IPR6", "url": "https://omabrowser.org/oma/group/A0A061IPR6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q500W4-1", "protein_name": "LIM domain-containing protein PLIM2c", "gene_name": "PLIM2C", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAAFTGTTDKCKACDKTVYVMDLMTLEGMPYHKSCFRCSHCNGTLVICNYSSMDGVLYCKTHFEQLFKESGNFSKNFQTAGKTEKSNDATKAPNRLSSFFSGTQDKCAACKKTVYPLEKMTMEGESYHKTCFRCAHSGCPLTHSSYAALDGVLYCKVHFSQLFLEKGNYNHVLQAAANHRRSTAEEDKTEPKEDEANPTEEETSDAAAEEHES", "length": 213 }, "evidence": [ { "id": "A0A061IPR6", "url": "https://omabrowser.org/oma/group/A0A061IPR6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q6Q6R3-3", "protein_name": "Cysteine-rich protein 3", "gene_name": "Crip3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSWTCPRCQQPVYFAEKVSSLGKNWHRFCLKCERCHSILSPGGHAEHNGRPYCHKPCYGALFGPRGVNIGGVGCYLYNLPTPPPASRISLSPSNFSPPRPRTGLSRAKKGPPYLKTFTGETSLCPGCGDPVFFAEKVMSLGRNWHRPCLRCQRCRKTLTAGSHAEHDGMPYCHIPCYGYLFGPKGVNIGDVGCYIYDPVDIRSK", "length": 204 }, "evidence": [ { "id": "A0A061IPR6", "url": "https://omabrowser.org/oma/group/A0A061IPR6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6Q6R5-1", "protein_name": "Cysteine-rich protein 3", "gene_name": "CRIP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSWTCPRCQQPVFFAEKVSSLGKNWHRFCLKCERCHSILSPGGHAEHNGRPYCHKPCYGALFGPRGVNIGGVGSYLYNPPTPSPGCTTPLSPSSFSPPRPRTGLPQGKKSPPHMKTFTGETSLCPGCGEPVYFAEKVMSLGRNWHRPCLRCQRCHKTLTAGSHAEHDGVPYCHVPCYGYLFGPKGGQPHPRHWDGMYMPEVWHVHGLWVCVDNFPCG", "length": 217 }, "evidence": [ { "id": "A0A061IPR6", "url": "https://omabrowser.org/oma/group/A0A061IPR6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A061IPR6", "url": "https://www.uniprot.org/uniprotkb/A0A061IPR6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 94, "end_pos": 96, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061IPR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IPR6" }, { "id": "PS50023", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50023" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 64, "start_aa": "Trp", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 94, "end_pos": 96 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061IQ17-1", "uniprot_ac": "A0A061IQ17", "uniprot_id": "A0A061IQ17_CRIGR", "mass": { "chemical_mass": 52476.0, "monoisotopic_mass": 52476.0 }, "refseq": { "ac": "XP_027249503", "name": "ankyrin repeat domain-containing protein 34A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249503" }, "gene_names": [ { "name": "Ankrd34a", "type": "recommended", "evidence": [ { "id": "A0A061IQ17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IQ17" } ] }, { "name": "Ankrd34a", "type": "synonym", "evidence": [ { "id": "XP_027249503", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249503" } ] } ], "protein_names": [ { "name": "Ankyrin repeat domain-containing protein 34A", "type": "synonym", "evidence": [ { "id": "A0A061IQ17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IQ17/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat domain-containing protein 34A", "type": "synonym", "evidence": [ { "id": "XP_027249503", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249503" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027249503", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249503" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IQ17", "url": "https://www.uniprot.org/uniprotkb/A0A061IQ17" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ankrd34a", "url": "https://www.uniprot.org/uniprotkb/A0A061IQ17", "locus": {} } ], "crossref": [ { "id": "100755248", "url": "https://www.ncbi.nlm.nih.gov/gene/100755248", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042637", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042637", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755248", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755248", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061IQ17", "url": "https://www.orthodb.org/?gene=A0A061IQ17", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24156", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24156", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24156:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24156:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027249503", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249503", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IQ17", "url": "https://www.uniprot.org/uniprotkb/A0A061IQ17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IQ17-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IQ17-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLHTEGHALLRAVGQGKLRLARLLLEGGAYVNEGDAQGETALMAACRARYDDPQNKARMVRYLLEQGADPNIADRLGRTALMHACAGGGGAAVASLLLAHGADPSVRDHAGASALVHALDRGDRETLATLLDACKAKGTEVIIITTDTSPSGTKKTRQYLNSPPSPGVEDPAPAPPSPGVCTSPSEVQLQTAGGGRGLLSPRAQEEEEKRDIFEFPLPKPPDDPSPSEPLPKPPRHPPKPLKRLNSEPWGLVAPPQPVPPAEGRPGMERLAAEFNGLTLTGRPRLSRRHSTEGPEDPPPWAEKVTGGGPLSRRNTAPEAQESGLPSGLRQKLSRMEPVELDTPGHFCPDSPEASRLALERRRYSASPLTLPPAGSVSSPRQSQESLPGAVSPLSGRRRSPGLLERRGSGTLLLDHISQTRPGFLPPLNVSPHPPIPDIRPQPGGRAPSLPAPPHSGAPGSPRTKRKLVRRHSMQTEQIRLLGGFQSLGGPGEPGR", "length": 495, "header": "tr|A0A061IQ17-1|A0A061IQ17_CRIGR Isoform 1 of Ankyrin repeat domain-containing protein 34A OS=Cricetulus griseus OX=10029 GN=Ankrd34a PE=3 SV=1 CANONICAL=A0A061IQ17-1" }, "isoforms": [ { "isoform_ac": "A0A061IQ17-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IQ17/entry#A0A061IQ17-1", "sequence": { "sequence": "MLHTEGHALLRAVGQGKLRLARLLLEGGAYVNEGDAQGETALMAACRARYDDPQNKARMVRYLLEQGADPNIADRLGRTALMHACAGGGGAAVASLLLAHGADPSVRDHAGASALVHALDRGDRETLATLLDACKAKGTEVIIITTDTSPSGTKKTRQYLNSPPSPGVEDPAPAPPSPGVCTSPSEVQLQTAGGGRGLLSPRAQEEEEKRDIFEFPLPKPPDDPSPSEPLPKPPRHPPKPLKRLNSEPWGLVAPPQPVPPAEGRPGMERLAAEFNGLTLTGRPRLSRRHSTEGPEDPPPWAEKVTGGGPLSRRNTAPEAQESGLPSGLRQKLSRMEPVELDTPGHFCPDSPEASRLALERRRYSASPLTLPPAGSVSSPRQSQESLPGAVSPLSGRRRSPGLLERRGSGTLLLDHISQTRPGFLPPLNVSPHPPIPDIRPQPGGRAPSLPAPPHSGAPGSPRTKRKLVRRHSMQTEQIRLLGGFQSLGGPGEPGR", "length": 495, "header": "tr|A0A061IQ17-1|A0A061IQ17_CRIGR Isoform 1 of Ankyrin repeat domain-containing protein 34A OS=Cricetulus griseus OX=10029 GN=Ankrd34a PE=3 SV=1 CANONICAL=A0A061IQ17-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"A0A061IQ68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IQ68" } ] }, { "name": "Tpm4", "type": "synonym", "evidence": [ { "id": "XP_003499135", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499135" } ] } ], "protein_names": [ { "name": "Tropomyosin alpha-4 chain isoform X1", "type": "synonym", "evidence": [ { "id": "A0A061IQ68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IQ68/entry#names_and_taxonomy" } ] }, { "name": "tropomyosin alpha-4 chain isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003499135", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499135" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613716.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 27, 2016 this sequence version replaced XP_003499135.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003499135", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499135" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IQ68", "url": "https://www.uniprot.org/uniprotkb/A0A061IQ68" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tpm4", "url": "https://www.uniprot.org/uniprotkb/A0A061IQ68", "locus": {} } ], "crossref": [ { "id": "100761146", "url": "https://www.ncbi.nlm.nih.gov/gene/100761146", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000533", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000533", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014751", "url": 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IQT4", "url": "https://www.uniprot.org/uniprotkb/A0A061IQT4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IQT4", "url": "https://www.uniprot.org/uniprotkb/A0A061IQT4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765635", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765635", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "aminoacyl-tRNA deacylase activity", "id": "GO:0002161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002161", "evidence": [ { "database": "UniProtKB", "id": "A0A061IQT4", "url": "https://www.uniprot.org/uniprotkb/A0A061IQT4" } ], "pmid": "" }, { "name": "aminoacyl-tRNA ligase activity", "id": "GO:0004812", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004812", "evidence": [ { "database": "UniProtKB", "id": "A0A061IQT4", "url": "https://www.uniprot.org/uniprotkb/A0A061IQT4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061IQT4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IQT4" }, { "id": "PF04073", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04073" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "YbaK/aminoacyl-tRNA synthetase-associated", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 153, "start_aa": "His", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061IQU7-1", "uniprot_ac": "A0A061IQU7", "uniprot_id": "A0A061IQU7_CRIGR", "mass": { "chemical_mass": 318013.0, "monoisotopic_mass": 318013.0 }, "refseq": { "ac": "XP_027248380", "name": "small subunit processome component 20 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248380" }, "gene_names": [ { "name": "Utp20", "type": "recommended", "evidence": [ { "id": "A0A061IQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IQU7" } ] }, { "name": "Utp20", "type": "synonym", "evidence": [ { "id": "XP_027248380", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248380" } ] } ], "protein_names": [ { "name": "Small subunit processome component 20 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "A0A061IQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IQU7/entry#names_and_taxonomy" } ] }, { "name": "small subunit processome component 20 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027248380", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248380" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027248380", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248380" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IQU7", "url": "https://www.uniprot.org/uniprotkb/A0A061IQU7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Utp20", "url": "https://www.uniprot.org/uniprotkb/A0A061IQU7", "locus": {} } ], "crossref": [ { "id": "100772924", "url": "https://www.ncbi.nlm.nih.gov/gene/100772924", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011430", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011430", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046523", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046523", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052575", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052575", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057525", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057525", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772924", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772924", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061IQU7", "url": "https://www.orthodb.org/?gene=A0A061IQU7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17695", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17695", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17695:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17695:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07539", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07539", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20416", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20416", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23099", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23099", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027248380", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027248380", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IQU7", "url": "https://www.uniprot.org/uniprotkb/A0A061IQU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IQU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IQU7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"MKPKPLSHKTENTYRFLTFAERLGNVNIDIIHRIDRTASYDEEVETYFFEALLKWRELNLTEHFGKFYKEVIDKCQSFNQLVYHQNEIVQSLKTHLQIRNSFAYQPLLDLVVQLARDLQTDFYPHFEDFFLTVTSILETQDTELLEWAFTSLSYLYKYLWRLMVKDMSKIYSMYSTLLAHKKLHIRNFAAESFTFLMRKVSDKNALFNLMFLDLNEHPEKVEGVGQLLFEMCKGVRNMFHSCTGQALKLILQKLGPVTETETQLPWILVGETLKNMAKSTVVYIYKEHFGIFFDCLQESLLELHNKVTEKNCCENSEQMSRLLETFLILVKHGSGSKITRPSDICRVLSEALQTDNLSTSCRKTLLDVVSALLLAENVSLPETLIKEIIEKIFESKFERRLIFDFSEVMFTMKQFEQLFLPSFLCYIENCFLIGDSVVCNEALAILAKLILNKAAPPTAGSMAIEKYPLVFSQQTVGSYLQQRKTDSKRRKEQSTVLDHLLAIVQSPPNKDTTYLSRSWAALVVLPHIRPLEKEKVLGLLSCFIDSLFMAVDKGSFGKGSLFVLCQAVNTLLSLEESSELLHLVPVERVKSLVLTFPAEPSVLLLADLYYQRLALCGCKGPLSEKALMELFPKLQANISTGVSKIRLLTIRILNHFDIQLPASMEDDGLSERQSAFAILRQAELVPATVSDYREKLLHLRKLRHDVVQDAAPQGPLQEVPLRYLLGMLYVNFSALWDPVIELISSHAHGMENKQFWSVCYEHLEKAAAHAEKELQKDMREAEQSTGDGSWEQAQEGDVGALYQQQLALKTDCRERLDHTNFRFLLWRALAKFPERIEPRSRELSPLFLRFINNEYYPADLQVAPTQDLRRKGRGAVAEVMEEEPAVEADEELEEEALPTDEAPQKKKTRRAAAKQLIAHLQVFSKFSNPRALYLESKLYELYLQLLLHQDQAVQKITLDCIMTYKHPHILPYRENLQRLLDDRSFKEEIVHFSISEDNTVVKATHRADLFPILMRILYGRMKNKTGSKTQGKSASGTRMAIVLRFLSGTQPGEIQLFLDLLSEPVKHFKNGECHSAVIRAVEDLDLSKVLPVGRQHGILNSLEVVLKTISHLISEYLPKILQILLCMTATVSHILEQREKIQLRFINPLKNLRRLGIKMISDIFLDWESYQFRAEEIDAVFHGAVWPQICRLGSESQYSPTPLLKLISIWSRNARYFPLLAKQKPGHPECDILTNVFAVLSAKNLSDATAGIIMDIVDDLLNLPDFEPTETMLSLPVTDCVYAEVADNTEPITVGGRLILPHVPAILQYLSKTTVSAEKVKKKKNRAQVSKELGILSKISKFMKDREQSSLLITLLLPFLLRGNVAQDTELDILVTVQNLLQHCQDPTSFLKPLAKLFSVIKNKLSRQLLCTVFQSLSGFESELKYITDIVKLNAFDKRHLDDINFDVRFSAFQTITSNIKEMQTVDADYLVPVMHNCFYNMELGDMSLSDNASMCLTSIIKKLAALNVTEKEYKEIIHRTLLEKLRKGLKSQTESVQHDYTMILSCLIQTFPNQVEFKDLVQLTHSHDPEMDFFENMKHIQIHRRARALKKLAKQLLERQVVLSSKSLQNYIMPYAMTPIFDEKMLKHENIIIAATEVIGAICRHLSWPAYVYYLKHFIHVLQTGQINQKLGVSLLVMVLEAFHFDYKTLEEQMGSVQDEENTVEMAELLEHEAMELEHVDEEEKEPARKSLSDEKEPLKTPDSGSIAATEQECISKSVSFLPRNKEELERTIKTIQGAITGDILPRLHKCLASATKREEEHKLVKSKVVNEEEVVRVPLAFAMVKLMRSLPQEVMEANLPSVLLKVCVLLKNRAQEVRDIARSTLSKIIEDLGVRFLQYVLKELQTTLVRGYQVHVLTFTVYTLLQGLTNKLQVGDLDPCLQIMTEIFNHELFGALAEEKEVKQILSKVMEARRSKSYDSYEILGKFVGKDQVTKLILPLKEILQNTTSLKLARKVHETLRRIIAGLIVNPDMTAESLLLLSYGLVSENLPLLTEKEKKPAAPAPDARLPPQSCLLLPPTPVRGGPKAVVSKKTNMHIFIESGLRLLHLSLKTSKIKSSSEHVLEMLDPFVSLLINCLGARDVKVITGSLQCLIWVLRFPLPSIESKAGQLTKHLFLLLKNYARLGAARGQNFHLVVNCFKCVTIVVKKVKSYQITEKQLQVLLAYAEEDIYDTTRQATAFGLLKAILSRKLLVPEIDDIMRKVSKLAISAQNEPARVQCRQVFLKYILDYPLGEKLRPNLEFMLAQLNYEHETGRESTLEMIAYLFDTFPQGLLHDTCGMFFIPLCLMMVNDDSAMCKKMASMAIKSLLSKVNLEKRDWLFGLVTSWFEAKKRLNRQLAALTCGLFVESEGVDFERRLGTLLPVIEKEINPENFKDIIEEVEEKAADRLLFGFLTLISKLIKECNIIHFTKPSETLNKIWSHVHSHLRHPHNWVWLTAAQIFGLLFASCQPEELIQKWKNKKTKKKPTEPVAVRFLTSDLDQKMKSISLASCHQLHSKFLDESLGEQVVKNLLFIAKVLYLLEPDSGNKLGESKGMEEQDTLGGALAREAAEDEAGTDGKMELDREEKEEPSKSATLLWLIQKLTRTAKLEAAYTPRNPLKRTCIFKFLGAVAVDLGVDRVQPYLPVIIAPLFRELNSTYSEQDPLLKNLSQEIIELLRKLVGLESFSLAFASVQKQASEKRALRKKRKALEFVTNPDVAAKKKLKKHKNKSEAKKRKIEFLRPGYKAKRQKSHSLRDLAIVE", "length": 2786, "header": "tr|A0A061IQU7-1|A0A061IQU7_CRIGR Isoform 1 of Small subunit processome component 20 homolog isoform X1 OS=Cricetulus griseus OX=10029 GN=Utp20 PE=4 SV=1 CANONICAL=A0A061IQU7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 458, "start_aa": "Thr", "end_pos": 458, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr458", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IQU7", "url": "https://www.uniprot.org/uniprotkb/A0A061IQU7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IQU7", "url": "https://www.uniprot.org/uniprotkb/A0A061IQU7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100772924", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772924", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "90S preribosome", "id": "GO:0030686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030686", "evidence": [ { "database": "UniProtKB", "id": "A0A061IQU7", "url": "https://www.uniprot.org/uniprotkb/A0A061IQU7" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "A0A061IQU7", "url": "https://www.uniprot.org/uniprotkb/A0A061IQU7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1023, "end_pos": 1025, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1244, "end_pos": 1246, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1492, "end_pos": 1494, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1508, "end_pos": 1510, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1988, "end_pos": 1990, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2680, "end_pos": 2682, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2692, "end_pos": 2694, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2753, "end_pos": 2755, "annotation": "n_glycosylation_sequon" }, { "start_pos": 356, "end_pos": 358, "annotation": "n_glycosylation_sequon" }, { "start_pos": 377, "end_pos": 379, "annotation": "n_glycosylation_sequon" }, { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" }, { 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF23099" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "U3 small nucleolar RNA-associated protein 20 C-terminal", "eco_id": "ECO_0000259", "start_pos": 2379, "end_pos": 2763, "start_aa": "Arg", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A061IQU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IQU7" }, { "id": "PF07539", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07539" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "U3 small nucleolar RNA-associated protein 20 N-terminal", "eco_id": "ECO_0000259", "start_pos": 911, "end_pos": 1533, "start_aa": "Ala", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 458 ], "snv_sites": [], "glycation_sites": [], 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A061IQW3-1", "uniprot_ac": "A0A061IQW3", "uniprot_id": "A0A061IQW3_CRIGR", "mass": { "chemical_mass": 33203.0, "monoisotopic_mass": 33203.0 }, "refseq": { "ac": "XP_003505367", "name": "protein NipSnap homolog 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505367" }, "gene_names": [ { "name": "Nipsnap1", "type": "recommended", "evidence": [ { "id": "A0A061IQW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IQW3" } ] }, { "name": "Nipsnap1", "type": "synonym", "evidence": [ { "id": "XP_003505367", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505367" } ] } ], "protein_names": [ { "name": "Protein NipSnap homolog 1", "type": "synonym", "evidence": [ { "id": "A0A061IQW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IQW3/entry#names_and_taxonomy" } ] }, { "name": "protein NipSnap homolog 1", "type": "synonym", "evidence": [ { "id": "XP_003505367", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505367" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614142.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003505367", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505367" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A061IQW3", "url": "https://www.uniprot.org/uniprotkb/A0A061IQW3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Nipsnap1", "url": "https://www.uniprot.org/uniprotkb/A0A061IQW3", "locus": {} } ], "crossref": [ { "id": "100773900", "url": "https://www.ncbi.nlm.nih.gov/gene/100773900", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012577", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012577", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051557", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051557", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773900", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773900", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NESSWFR", "url": "https://omabrowser.org/oma/group/NESSWFR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A061IQW3", "url": "https://www.orthodb.org/?gene=A0A061IQW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21017", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21017", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21017:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21017:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07978", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07978", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003505367", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505367", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061IQW3", "url": "https://www.uniprot.org/uniprotkb/A0A061IQW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061IQW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IQW3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPRLCIISASARRLLGKPGPRAGDLAAAAAVRFYSKDSEGSWFRSLFVHKVDPRKDAHSTLLSKKETSNLYKIQFHNVKPECLDAYNSLTEAVLPKLHLDEDYPCSLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLKTNKEYLEFRKERSKMLLSRRNQLLLEFSFWNEPQPRAGPNIYELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDLQSREETRNAAWRKRGWDENVYYTVPLVRHMESRIMIPLKISPLQ", "length": 284, "header": "tr|A0A061IQW3-1|A0A061IQW3_CRIGR Isoform 1 of Protein NipSnap homolog 1 OS=Cricetulus griseus OX=10029 GN=Nipsnap1 PE=3 SV=1 CANONICAL=A0A061IQW3-1" }, "isoforms": [ { "isoform_ac": "A0A061IQW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A061IQW3/entry#A0A061IQW3-1", "sequence": { "sequence": "MAPRLCIISASARRLLGKPGPRAGDLAAAAAVRFYSKDSEGSWFRSLFVHKVDPRKDAHSTLLSKKETSNLYKIQFHNVKPECLDAYNSLTEAVLPKLHLDEDYPCSLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLKTNKEYLEFRKERSKMLLSRRNQLLLEFSFWNEPQPRAGPNIYELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDLQSREETRNAAWRKRGWDENVYYTVPLVRHMESRIMIPLKISPLQ", "length": 284, "header": "tr|A0A061IQW3-1|A0A061IQW3_CRIGR Isoform 1 of Protein NipSnap homolog 1 OS=Cricetulus griseus OX=10029 GN=Nipsnap1 PE=3 SV=1 CANONICAL=A0A061IQW3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IQW3", "url": "https://www.uniprot.org/uniprotkb/A0A061IQW3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IQW3", "url": "https://www.uniprot.org/uniprotkb/A0A061IQW3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773900", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773900", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5NYA0-1", "protein_name": "Nipsnap homolog 1", "gene_name": "NIPSNAP1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAARAGGGAVLLRRLQGGGGGGGAFSGARAYSRDAEGSWFRSLFVHKVDPRKDAHSNLLSKKETSNLYKIQFHNVKPECLDAYNSLTEEVLPKLHSDADYPCDLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLKQNKEYLDFRKERSRMLLSRRNQLLLEFSFWNEPLPRKGPNIYELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDLQSREETRNAAWRKRGWDENVYYTVPLIRTMESRIMIPLKISPLQ", "length": 281 }, "evidence": [ { "id": "A0A061IQW3", "url": "https://omabrowser.org/oma/group/A0A061IQW3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3V728-1", "protein_name": "Nipsnap homolog 1", "gene_name": "Nipsnap1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPRLCIISAAARRLLRKPGPCVGDLAAARAVRFYSKDSEGSWFRSLFVHKVDPRKDAHSTLLSKKETSNLYKIQFHNVKPECLDAYNSLTEAVLPKLHLDEDYPCSLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLKTNKEYLEFRKERSKMLLSRRNQLLLEFSFWNEPQPRAGPNIYELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDLQSREETRNAAWRKRGWDENVYYTVPLVRHMESRIMIPLKISPLQ", "length": 284 }, "evidence": [ { "id": "A0A061IQW3", "url": "https://omabrowser.org/oma/group/A0A061IQW3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O55125-1", "protein_name": "Protein NipSnap homolog 1", "gene_name": "Nipsnap1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPRLCIISAAARRLFTKPRPRAGDLAAAGAVRFYSKDSEGSWFRSLFVHKVDPRKDAHSTLLSKKETSNLYKIQFHNVKPECLDAYNSLTEAVLPKLHLDEDYPCSLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLKNNKEYLEFRKERSKMLLSRRNQLLLEFSFWNEPQPRAGPNIYELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDLQSREETRNAAWRKRGWDENVYYTVPLVRHMESRIMIPLKISPLQ", "length": 284 }, "evidence": [ { "id": "A0A061IQW3", "url": "https://omabrowser.org/oma/group/A0A061IQW3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BPW8-1", "protein_name": "Protein NipSnap homolog 1", "gene_name": "NIPSNAP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPRLCSISVTARRLLGGPGPRAGDVASAAAARFYSKDNEGSWFRSLFVHKVDPRKDAHSTLLSKKETSNLYKIQFHNVKPEYLDAYNSLTEAVLPKLHLDEDYPCSLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLKNNKEYLEFRRERSQMLLSRRNQLLLEFSFWNEPQPRMGPNIYELRTYKLKPGTMIEWGNNWARAIKYRQENQEAVGGFFSQIGELYVVHHLWAYKDLQSREETRNAAWRKRGWDENVYYTVPLVRHMESRIMIPLKISPLQ", "length": 284 }, "evidence": [ { "id": "A0A061IQW3", "url": 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"" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061IQW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IQW3" }, { "id": "PF07978", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07978" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NIPSNAP", "eco_id": "ECO_0000259", "start_pos": 185, "end_pos": 282, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], 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This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061IRE8", "url": "https://www.uniprot.org/uniprotkb/A0A061IRE8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:113833389", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113833389", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A061IRE8", "url": "https://www.uniprot.org/uniprotkb/A0A061IRE8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "A0A061IRE8", "url": "https://www.uniprot.org/uniprotkb/A0A061IRE8" } ], "pmid": "" }, { "name": "growth factor activity", "id": "GO:0008083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008083", "evidence": [ { "database": "UniProtKB", "id": "A0A061IRE8", "url": "https://www.uniprot.org/uniprotkb/A0A061IRE8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A061IRE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A061IRE8" }, { "id": "PS51362", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51362" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TGF-beta family profile", "eco_id": "ECO_0000259", "start_pos": 238, "end_pos": 357, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 314 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 195, "end_pos": 197 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", 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"title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A098KXC5-1", "uniprot_ac": "A0A098KXC5", "uniprot_id": "A0A098KXC5_CRIGR", "mass": { "chemical_mass": 60944.0, "monoisotopic_mass": 60944.0 }, "refseq": { "ac": "XP_027264184", "name": "solute carrier family 22 member 19 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264184" }, "gene_names": [ { "name": "LOC100773204", "type": "recommended", "evidence": [ { "id": "A0A098KXC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A098KXC5" } ] }, { "name": "LOC100773204", "type": "synonym", "evidence": [ { "id": "XP_027264184", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264184" } ] } ], "protein_names": [ { "name": "Solute carrier family 22 member 19 isoform X3", "type": "synonym", "evidence": [ { "id": "A0A098KXC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A098KXC5/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 22 member 19 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027264184", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264184" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027264184", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264184" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A098KXC5", "url": "https://www.uniprot.org/uniprotkb/A0A098KXC5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100773204", "url": "https://www.uniprot.org/uniprotkb/A0A098KXC5", "locus": {} } ], "crossref": [ { "id": "cd17374", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17374", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100773204", "url": "https://www.ncbi.nlm.nih.gov/gene/100773204", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005829", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005829", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773204", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773204", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7GW41", "url": "https://www.orthodb.org/?gene=A0A9J7GW41", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24064", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24064", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00083", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00083", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027264184", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264184", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A098KXC5", "url": "https://www.uniprot.org/uniprotkb/A0A098KXC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A098KXC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A098KXC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GW41", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GW41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GW41-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GW41-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFQDLLIHTGSLGRFQLLQMAFLLICNGFVGPHSLLENFTAAIPGHRCWVPILDNVTVSDNDSGILSQDDLLRISIPLDSNLRPDKCRRFVQPQWHLLHLNGTFPNVTEPDTEPCVDGWVYDRSTFLSTTVSQWDLVCGSQALHSVAKFIFMFGIFLGHIIGGYLSDRFGRKFVFTGALLQMTITETCAAFAPNFLIYCSCRFLAGISSSSIRTNSVLLIVEWTSPKFQSLVMTLAFAAGGIGQVILGSLAFAIRNWHHLQLAMAIPMFFFLIPARWLSESARWLIMTNKPQKGLKELQRAACKNGKQSSRDVLTMEVVRNAMKEELEAAQTKHSVLDLFRTPSLRKRICILCLMRFMSLIPIMGMFIHLQHLSSNVFLLQCLYGVIAIPANALGNFSMNHMGRRITQLIFLSLLGIFILSTIFLSQEMQTLRIILATLGGAISSACVSSTLVHANELVPTVIRATGLGVAGIAGSAGAAISPLFMIFTIYSASLPWIIYGVFPIITGLIALLLPETKNQPLPDSIQDVENERKSSREAKKNAVSKVTPF", "length": 551, "header": "tr|A0A098KXC5-1|A0A098KXC5_CRIGR Isoform 1 of Solute carrier family 22 member 19 isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC100773204 PE=4 SV=1 CANONICAL=A0A098KXC5-1" }, "isoforms": [ { "isoform_ac": "A0A098KXC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A098KXC5/entry#A0A098KXC5-1", "sequence": { "sequence": "MAFQDLLIHTGSLGRFQLLQMAFLLICNGFVGPHSLLENFTAAIPGHRCWVPILDNVTVSDNDSGILSQDDLLRISIPLDSNLRPDKCRRFVQPQWHLLHLNGTFPNVTEPDTEPCVDGWVYDRSTFLSTTVSQWDLVCGSQALHSVAKFIFMFGIFLGHIIGGYLSDRFGRKFVFTGALLQMTITETCAAFAPNFLIYCSCRFLAGISSSSIRTNSVLLIVEWTSPKFQSLVMTLAFAAGGIGQVILGSLAFAIRNWHHLQLAMAIPMFFFLIPARWLSESARWLIMTNKPQKGLKELQRAACKNGKQSSRDVLTMEVVRNAMKEELEAAQTKHSVLDLFRTPSLRKRICILCLMRFMSLIPIMGMFIHLQHLSSNVFLLQCLYGVIAIPANALGNFSMNHMGRRITQLIFLSLLGIFILSTIFLSQEMQTLRIILATLGGAISSACVSSTLVHANELVPTVIRATGLGVAGIAGSAGAAISPLFMIFTIYSASLPWIIYGVFPIITGLIALLLPETKNQPLPDSIQDVENERKSSREAKKNAVSKVTPF", "length": 551, "header": "tr|A0A098KXC5-1|A0A098KXC5_CRIGR Isoform 1 of Solute carrier family 22 member 19 isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC100773204 PE=4 SV=1 CANONICAL=A0A098KXC5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GW41-1", "url": "https://www.uniprot.org/uniprotkb/A0A098KXC5/entry#A0A9J7GW41-1", "sequence": { "sequence": "MAFQDLLIHTGSLGRFQLLQMAFLLICNGFVGPHSLLENFTAAIPGHRCWVPILDNVTVSDNDSGILSQDDLLRISIPLDSNLRPDKCRRFVQPQWHLLHLNGTFPNVTEPDTEPCVDGWVYDRSTFLSTTVSQWDLVCGSQALHSVAKFIFMFGIFLGHIIGGYLSDRFGRKFVFTGALLQMTITETCAAFAPNFLIYCSCRFLAGISSSSIRTNSVLLIVEWTSPKFQSLVMTLAFAAGGIGQVILGSLAFAIRNWHHLQLAMAIPMFFFLIPARWLSESARWLIMTNKPQKGLKELQRAACKNGKQSSRDVLTMEVVRNAMKEELEAAQTKHSVLDLFRTPSLRKRICILCLMRFMSLIPIMGMFIHLQHLSSNVFLLQCLYGVIAIPANALGNFSMNHMGRRITQLIFLSLLGIFILSTIFLSQEMQTLRIILATLGGAISSACVSSTLVHANELVPTVIRATGLGVAGIAGSAGAAISPLFMIFTIYSASLPWIIYGVFPIITGLIALLLPETKNQPLPDSIQDVENDWKSSREAKKNAVSKVTPF", "length": 551, "header": "tr|A0A9J7GW41-1|A0A9J7GW41_CRIGR Computationally mapped isoform of Solute carrier family 22 member 19 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100773204 PE=4 SV=1 CANONICAL=A0A098KXC5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": 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MODEL REFSEQ: This record is predicted by automated computational analysis. 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Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613871.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003502052", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502052" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7GQX1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GQX1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Snrnp48", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GQX1", "locus": {} } ], "crossref": [ { "id": "100766215", "url": "https://www.ncbi.nlm.nih.gov/gene/100766215", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR022776", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022776", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766215", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766215", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QEPMEQC", "url": "https://omabrowser.org/oma/group/QEPMEQC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7GQX1", "url": "https://www.orthodb.org/?gene=A0A3L7GQX1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21402", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21402", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21402:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21402:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05253", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05253", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003502052", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502052", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7GQX1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GQX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7GQX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GQX1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAEPPPLEERRRLQEELSEFVESCCRTLEEVTASLGWSLDQLDPGDQAEAEDEVTICPYDSNHHMPKSSLAKHMESCRLRKLGYAKEEEDEMHNPAFFYENLKIPSVTLNKDSQFQIIKQARTAAGKDGDCYSPRMYSSVPVEVPLNHKRSVCDLTQADRLALYDFVIEETKKNRSGSQVIENDSDLFVDLAAKVNQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKNVHITKKSYTEVIRDVIKVHMEELSNHWQEEQERAEDGAEKNEERRSASVDSRQSGGSYLDVENSRHRRARSRSPHKRKRNKDKNSESRRRKERDGERHHSHKRRKQKI", "length": 337, "header": "tr|A0A3L7GQX1-1|A0A3L7GQX1_CRIGR Isoform 1 of U11/U12 small nuclear ribonucleoprotein 48 kDa protein OS=Cricetulus griseus OX=10029 GN=Snrnp48 PE=4 SV=1 CANONICAL=A0A3L7GQX1-1" }, "isoforms": [ { "isoform_ac": "A0A3L7GQX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GQX1/entry#A0A3L7GQX1-1", "sequence": { "sequence": "MEAEPPPLEERRRLQEELSEFVESCCRTLEEVTASLGWSLDQLDPGDQAEAEDEVTICPYDSNHHMPKSSLAKHMESCRLRKLGYAKEEEDEMHNPAFFYENLKIPSVTLNKDSQFQIIKQARTAAGKDGDCYSPRMYSSVPVEVPLNHKRSVCDLTQADRLALYDFVIEETKKNRSGSQVIENDSDLFVDLAAKVNQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKNVHITKKSYTEVIRDVIKVHMEELSNHWQEEQERAEDGAEKNEERRSASVDSRQSGGSYLDVENSRHRRARSRSPHKRKRNKDKNSESRRRKERDGERHHSHKRRKQKI", "length": 337, "header": "tr|A0A3L7GQX1-1|A0A3L7GQX1_CRIGR Isoform 1 of U11/U12 small nuclear ribonucleoprotein 48 kDa protein OS=Cricetulus griseus OX=10029 GN=Snrnp48 PE=4 SV=1 CANONICAL=A0A3L7GQX1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7GQX1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GQX1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7GQX1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GQX1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766215", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766215", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1B7L0-1", "protein_name": "Small nuclear ribonucleoprotein U11/U12 subunit 48", "gene_name": "SNRNP48", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEAELPPVEERRRLREELSEFVESCRRTLEEVTASLGWSLDRLEPGEEAAAAEDEVAICPYDSNHHMPRSSLAKHMMSCRLRRLGYTKEEEDKMYNSDFFYENANVPSITLNKDSQFQIIKQARAAVGNDGDYYNQRLYSSLPIEVPLNHKRFVCDLTQADRLALYDFVVEETKKKRSDSQIIENDSDLFVDLAAKVNQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKNVHITKKSYTEVIRDVINVHMEELSSHWQEEQEKEADGADKSEERRSASVDSRHSGGSHLDGECSRHRRDRSRSPHRRKRNKDKDRGWDSRRRKERDGERHHSHKRRKQKM", "length": 340 }, "evidence": [ { "id": "A0A3L7GQX1", "url": "https://omabrowser.org/oma/group/A0A3L7GQX1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9D361-1", "protein_name": "U11/U12 small nuclear ribonucleoprotein 48 kDa protein", "gene_name": "Snrnp48", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METEPPPLEERRRLQEELSEFVESCCRTLEEVTASLGWSLDQLDPGDEAEAEDEIAICPYDSNHRMPKSSLTKHMESCRLRKLGYTKEEENEMYNPTFFYENLKIPSVTLNKDSQFQIIKQARTTAGKDGDCYSQRMYSSVPVEVPLNHKRSVCDLTQTDRLALYDFVIEETKKKRSGPQVIENDSDLFVDLAAKVNQDNSRKSPKSYLEILAEVRDYKRRRQSYRAKNVHITKKSYTEVIRDVIKVHMEELSSHWQEEQGRAGDAAEKNEERRSASVDSRQSGGSYLDVESSRHRRARSRSPHKRKRNKDKSSESRRRKERDGERHHSHKRRKQKI", "length": 337 }, "evidence": [ { "id": "A0A3L7GQX1", "url": "https://omabrowser.org/oma/group/A0A3L7GQX1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7GQX1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GQX1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7GQX1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GQX1" } ], "pmid": "" }, { "name": "U12-type spliceosomal complex", "id": "GO:0005689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005689", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7GQX1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GQX1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7GQX1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GQX1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 175, "end_pos": 177, "annotation": "n_glycosylation_sequon" }, { "start_pos": 184, "end_pos": 186, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3L7GQX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GQX1" }, { "id": "PS51800", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51800" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CHHC U11-48K-type", "eco_id": "ECO_0000259", "start_pos": 55, "end_pos": 82, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 175, "end_pos": 177 }, { "start_pos": 184, "end_pos": 186 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"uniprot_canonical_ac": "A0A3L7GR66-1", "uniprot_ac": "A0A3L7GR66", "uniprot_id": "A0A3L7GR66_CRIGR", "mass": { "chemical_mass": 58944.0, "monoisotopic_mass": 58944.0 }, "refseq": { "ac": "XP_027246435", "name": "uncharacterized protein C14orf93 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246435" }, "gene_names": [ { "name": "CUNH14orf93", "type": "recommended", "evidence": [ { "id": "A0A3L7GR66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GR66" } ] }, { "name": "CUNH14orf93", "type": "synonym", "evidence": [ { "id": "XP_027246435", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246435" } ] } ], "protein_names": [ { "name": "Uncharacterized protein C14orf93 homolog", "type": "synonym", "evidence": [ { "id": "A0A3L7GR66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GR66/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C14orf93 homolog", "type": "synonym", "evidence": [ { "id": "XP_027246435", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246435" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027246435", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246435" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7GR66", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GR66" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "CUNH14orf93", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GR66", "locus": {} } ], "crossref": [ { "id": "100765644", "url": "https://www.ncbi.nlm.nih.gov/gene/100765644", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028101", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028101", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765644", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765644", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FDQSHKT", "url": "https://omabrowser.org/oma/group/FDQSHKT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7GR66", "url": "https://www.orthodb.org/?gene=A0A3L7GR66", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14375", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14375", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14375:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14375:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15394", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15394", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027246435", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246435", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7GR66", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GR66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7GR66-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GR66-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFSATILFSPPSGSEARCCCCTCKSETSQGSSGSQGGNPPASTPITVTGHGLAVQSSEQLLHIIYQRVDKAVGLAEAALGLARANNELLKQLQEEVGELRQGKVCTADEDGEHRARSPPPEEPGLLKGSPGEACKTLSAMEEECDSVGSGVQVVIEELRQLGAASTVGQGPLGFFAAPQRDLRLPGCALAAVEGAPLLNPMADDYVASEGAVQRVLVPAYAKQLSPATQLAIQRASSETGPENGTKLPATRPEDMLGSAALDNAMEESGPGGTGELGRSMGFIGSPCRIRGTGQKNSRRKRDLVLSKLVHNVHNHITNDKRFNGSESIKSSWNISVVKFLLEKLKQELMTSPHNYTDKELKGACVAYFLTKRREYRNSLNPFKGLKEKEEKKLRSRRYRLFANRSSIMRHFGPEDQQLWKNVTEELMSDEEDSLNEPGVWVARSPRFRAQRLTELCYHLDANSKHGTKANRVYGPPSDRLPSVEAQLLPPELYNPNFQEDGGGGGNEKGPVSPSFDQPHKTSCPDLNSFIEIKVEKDEYSL", "length": 542, "header": "tr|A0A3L7GR66-1|A0A3L7GR66_CRIGR Isoform 1 of Uncharacterized protein C14orf93 homolog OS=Cricetulus griseus OX=10029 GN=CUNH14orf93 PE=4 SV=1 CANONICAL=A0A3L7GR66-1" }, "isoforms": [ { "isoform_ac": "A0A3L7GR66-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GR66/entry#A0A3L7GR66-1", "sequence": { "sequence": "MSFSATILFSPPSGSEARCCCCTCKSETSQGSSGSQGGNPPASTPITVTGHGLAVQSSEQLLHIIYQRVDKAVGLAEAALGLARANNELLKQLQEEVGELRQGKVCTADEDGEHRARSPPPEEPGLLKGSPGEACKTLSAMEEECDSVGSGVQVVIEELRQLGAASTVGQGPLGFFAAPQRDLRLPGCALAAVEGAPLLNPMADDYVASEGAVQRVLVPAYAKQLSPATQLAIQRASSETGPENGTKLPATRPEDMLGSAALDNAMEESGPGGTGELGRSMGFIGSPCRIRGTGQKNSRRKRDLVLSKLVHNVHNHITNDKRFNGSESIKSSWNISVVKFLLEKLKQELMTSPHNYTDKELKGACVAYFLTKRREYRNSLNPFKGLKEKEEKKLRSRRYRLFANRSSIMRHFGPEDQQLWKNVTEELMSDEEDSLNEPGVWVARSPRFRAQRLTELCYHLDANSKHGTKANRVYGPPSDRLPSVEAQLLPPELYNPNFQEDGGGGGNEKGPVSPSFDQPHKTSCPDLNSFIEIKVEKDEYSL", "length": 542, "header": "tr|A0A3L7GR66-1|A0A3L7GR66_CRIGR Isoform 1 of Uncharacterized protein C14orf93 homolog OS=Cricetulus griseus OX=10029 GN=CUNH14orf93 PE=4 SV=1 CANONICAL=A0A3L7GR66-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NW_003614213.1) and transcript sequence (IACG01204609.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003506172", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506172" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7GR87", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GR87" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Haus4", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GR87", "locus": {} } ], "crossref": [ { "id": "100769299", "url": "https://www.ncbi.nlm.nih.gov/gene/100769299", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029327", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029327", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769299", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769299", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3L7GR87", "url": "https://www.orthodb.org/?gene=A0A3L7GR87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16219", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16219", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16219:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16219:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14735", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14735", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003506172", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506172", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7GR87", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GR87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7GR87-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GR87-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASGDFCAPGEGVEILQQVCDKQFPPCALTEEDLIQNPHFSKLLLSLSQHLDESGLSLTLAKEQAQAWNEVRLHKTAWLRYEILQRVIQELLVDYYVKAQDTNLTSEDKKFHETLEQRLLVTELTQLSSPGQEMEMPSLLGLKKADLLELMPPSQDFVWMRARLQLEVEEQLKRKCFTLLCYHDPSSDTDGETLKAAKVWRLSEVLVREKQQCLEAKGQHKEQLVLLEKRRATYFQVLLRCLTLLQRLLQEHRLKTQSELDRINAQYLEIKCSAMILKMRMEELKILSDTYSAEKVEVHRLIRDRLEGAIRLQEQDMEKSRLVLKNYEVLGEDFENLVKEYTQLKLAAENKRWALQEFSKA", "length": 361, "header": "tr|A0A3L7GR87-1|A0A3L7GR87_CRIGR Isoform 1 of HAUS augmin-like complex subunit 4 OS=Cricetulus griseus OX=10029 GN=Haus4 PE=4 SV=1 CANONICAL=A0A3L7GR87-1" }, "isoforms": [ { "isoform_ac": "A0A3L7GR87-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GR87/entry#A0A3L7GR87-1", "sequence": { "sequence": "MASGDFCAPGEGVEILQQVCDKQFPPCALTEEDLIQNPHFSKLLLSLSQHLDESGLSLTLAKEQAQAWNEVRLHKTAWLRYEILQRVIQELLVDYYVKAQDTNLTSEDKKFHETLEQRLLVTELTQLSSPGQEMEMPSLLGLKKADLLELMPPSQDFVWMRARLQLEVEEQLKRKCFTLLCYHDPSSDTDGETLKAAKVWRLSEVLVREKQQCLEAKGQHKEQLVLLEKRRATYFQVLLRCLTLLQRLLQEHRLKTQSELDRINAQYLEIKCSAMILKMRMEELKILSDTYSAEKVEVHRLIRDRLEGAIRLQEQDMEKSRLVLKNYEVLGEDFENLVKEYTQLKLAAENKRWALQEFSKA", "length": 361, "header": "tr|A0A3L7GR87-1|A0A3L7GR87_CRIGR Isoform 1 of HAUS augmin-like complex subunit 4 OS=Cricetulus griseus OX=10029 GN=Haus4 PE=4 SV=1 CANONICAL=A0A3L7GR87-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"name": "Spink13", "type": "synonym", "evidence": [ { "id": "XP_003499510", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499510" } ] } ], "protein_names": [ { "name": "Serine protease inhibitor Kazal-type 13", "type": "synonym", "evidence": [ { "id": "A0A3L7GUF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7GUF7/entry#names_and_taxonomy" } ] }, { "name": "serine protease inhibitor Kazal-type 13", "type": "synonym", "evidence": [ { "id": "XP_003499510", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499510" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; 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This record is derived from a genomic sequence (NW_003613738.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_003614493.1) annotated using gene prediction method: Gnomon. 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], "protein_names": [ { "name": "Bone morphogenetic protein 15", "type": "synonym", "evidence": [ { "id": "A0A3L7H225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H225/entry#names_and_taxonomy" } ] }, { "name": "bone morphogenetic protein 15", "type": "synonym", "evidence": [ { "id": "XP_003505851", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505851" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614190.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003505851.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003505851", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505851" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H225", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H225" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Bmp15", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H225", "locus": {} } ], "crossref": [ { "id": "100756159", "url": "https://www.ncbi.nlm.nih.gov/gene/100756159", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001839", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001839", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015615", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015615", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017948", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017948", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756159", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756159", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VYRHQLH", "url": "https://omabrowser.org/oma/group/VYRHQLH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7H225", "url": "https://www.orthodb.org/?gene=A0A3L7H225", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11848", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11848", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11848:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11848:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00019", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00019", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003505851", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505851", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7H225", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H225", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7H225-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H225-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALLTILKILFWGMVFFMEHRVQMAKAGWPSITRLADDPTLPLNLDLAKEASGKEMKPRPQGYPLRYMLKLYQRSADLHGHPRENRTIGAKMVRLVKPSANVVRPLRGPWHVQILDFPLTSNQVAYQLIRATVVYRHQLHLVHYHLSCHVEPWIPKCLAKHFPSSEAGSSKLPPMSKAWTEMDITHCVQQRLWNRKGRRILRLRFMCQQQKGSEVLEFQWHGMSSLDVAFLLLYFNDTDRSVQAKLLAQGQEELTDRESSVLMRSARQACSIASDVPCHSQEHDGSINNQCSLHPYKVSFHQLGWDHWIIAPRLYTPNYCKGFCSRVLPYGLNSPNHAIIQSLVNELVNHSVPQPSCVPYKFLPMSILLVEANGSILYKEYEGMIAQSCTCR", "length": 392, "header": "tr|A0A3L7H225-1|A0A3L7H225_CRIGR Isoform 1 of Bone morphogenetic protein 15 OS=Cricetulus griseus OX=10029 GN=Bmp15 PE=3 SV=1 CANONICAL=A0A3L7H225-1" }, "isoforms": [ { "isoform_ac": "A0A3L7H225-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H225/entry#A0A3L7H225-1", "sequence": { "sequence": "MALLTILKILFWGMVFFMEHRVQMAKAGWPSITRLADDPTLPLNLDLAKEASGKEMKPRPQGYPLRYMLKLYQRSADLHGHPRENRTIGAKMVRLVKPSANVVRPLRGPWHVQILDFPLTSNQVAYQLIRATVVYRHQLHLVHYHLSCHVEPWIPKCLAKHFPSSEAGSSKLPPMSKAWTEMDITHCVQQRLWNRKGRRILRLRFMCQQQKGSEVLEFQWHGMSSLDVAFLLLYFNDTDRSVQAKLLAQGQEELTDRESSVLMRSARQACSIASDVPCHSQEHDGSINNQCSLHPYKVSFHQLGWDHWIIAPRLYTPNYCKGFCSRVLPYGLNSPNHAIIQSLVNELVNHSVPQPSCVPYKFLPMSILLVEANGSILYKEYEGMIAQSCTCR", "length": 392, "header": "tr|A0A3L7H225-1|A0A3L7H225_CRIGR Isoform 1 of Bone morphogenetic protein 15 OS=Cricetulus griseus OX=10029 GN=Bmp15 PE=3 SV=1 CANONICAL=A0A3L7H225-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H225", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H225" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H225", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H225" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756159", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756159", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E9PTU9-1", "protein_name": "Bone morphogenetic protein 15", "gene_name": "Bmp15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLTILRILLWGMVLFMEHKVQMAKVEWPSTTLLAENPTLPSSLDLAKEAPGKEMKQWPQGYPLRYMLKLYQRSADPHGHPRENRTIGAKMVRLIKPSASAMRLLRGPWHIQTLDFPLASNEVAYQLIRATVVYRHQLHLVHYHLSCHVEPWVPKCRTKHFPSKSGSAKPSSVSKAWREMNITHCIQQKLWNRKGRRVLRLRFMCQQQKGNETLELRWHGMTSLDVAFLLLYFNDTDESAQAKLLARGQEELTDRESPFLMRSVRQTCSIASDVPCPSQEQDRSVNNQCSLHPYKVSFHQLGWDHWIIAPRLYTPNYCKGICTGVLPYGLNSPNHAIIQSLVNELVNRSVPQLSCVPYKFLPMSILLIEANGSILYKEYEGMIAQSCTCR", "length": 391 }, "evidence": [ { "id": "A0A3L7H225", "url": "https://omabrowser.org/oma/group/A0A3L7H225/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RV73-1", "protein_name": "Bone morphogenetic protein 15", "gene_name": "BMP15", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLLNKSFKMVLLSIIRTLLLWGLVLFMEHRVQMTQVGQPSVALLPEACTLPLIRELLEEAPGKQQRKPQVLGHPLRYMLELYQRSADARGHPRENRTIGATMVRLVRPLVNGARPLRGPWHIQTLDFPLRPNRVAYQLVRATVVYRHQLHLAPFHLSCHVEPWIQKSTTSHFPSSGRGSLKPSLLPQAWTEMDVTQHVGQKLWNHKGRRVLRLRFMCQQQNGSEILEFRGRGISSLDTAFLLLYFNDTRSVQKAKLLPRGLEEFMARDPSLLLRKARQAGSIASEVLGPSREHDGPESNQCSLHPFQVSFHQLGWDHWIIAPHFYTPNYCKGVCPRVLHYGLNSPNHAIIQNLVNELVDQSVPQPSCVPYKYVPISILLIEANGSILYKEYEDMIAQSCTCR", "length": 402 }, "evidence": [ { "id": "A0A3L7H225", "url": "https://omabrowser.org/oma/group/A0A3L7H225/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O95972-1", "protein_name": "Bone morphogenetic protein 15", "gene_name": "BMP15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVLLSILRILFLCELVLFMEHRAQMAEGGQSSIALLAEAPTLPLIEELLEESPGEQPRKPRLLGHSLRYMLELYRRSADSHGHPRENRTIGATMVRLVKPLTNVARPHRGTWHIQILGFPLRPNRGLYQLVRATVVYRHHLQLTRFNLSCHVEPWVQKNPTNHFPSSEGDSSKPSLMSNAWKEMDITQLVQQRFWNNKGHRILRLRFMCQQQKDSGGLELWHGTSSLDIAFLLLYFNDTHKSIRKAKFLPRGMEEFMERESLLRRTRQADGISAEVTASSSKHSGPENNQCSLHPFQISFRQLGWDHWIIAPPFYTPNYCKGTCLRVLRDGLNSPNHAIIQNLINQLVDQSVPRPSCVPYKYVPISVLMIEANGSILYKEYEGMIAESCTCR", "length": 392 }, "evidence": [ { "id": "A0A3L7H225", "url": "https://omabrowser.org/oma/group/A0A3L7H225/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6PX77-1", "protein_name": "Bone morphogenetic protein 15", "gene_name": "BMP15", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVLLSILRILLLWGLVLFMEHRVQMTQVGQPSIAHLPEAPTLPLIQELLEEAPGKQQRKPRILGHPLRYMLELYQRSADASGHPRENRTIGATMVRLVRPLASVARPLRGSWHIQTLDFPLRPNRVAYQLVRATVVYRHQLHLTHSHLSCHVEPWVQKSPTNHFPSSGRGSSKPSLLPKAWTEMDIMEHVGQKLWNHKGRRVLRLRFVCQQPRGSEVREFWWHGTSSLDTVFLLLYFNDTQSVQKTKPLPKGLKEFTEKDPSLLLRRARQAGSIASEVPGPSREHDGPESNLCSLHPFQVSFQQLGWDHWIIAPHLYTPNYCKGVCPRVLHYGLNSPNHAIIQNLVNELVDQSVPQPSCVPYKYVPISILLIEANGSILYKEYEGMIAQSCTCR", "length": 394 }, "evidence": [ { "id": "A0A3L7H225", "url": "https://omabrowser.org/oma/group/A0A3L7H225/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9Z0L4-1", "protein_name": "Bone morphogenetic protein 15", "gene_name": "Bmp15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALLTILRILLWGVVLFMEQRVQMAKPGWPSTALLADDPTLPSILDLAKEAPGKEMKQWPQGYPLRYMLKLYHRSADPHGHPRENRTIGAKMVRLVKPSANTVRPPRGSWHVQTLDFPLASNQVAYELIRATVVYRHQLHLVNYHLSCHVETWVPKCRTKHLPSSKSGSSKPSPMSKAWTEIDITHCIQQKLWNRKGRSVLRLRFMCQQQKGNETREFRWHGMTSLDVAFLLLYFNDTDDRVQGKLLARGQEELTDRESSFLMRSVRQACSIESDASCPSQEHDGSVNNQCSLHPYKVSFHQLGWDHWIIAPRLYTPNYCKGICTRVLPYGLNSPNHAIIQSLVNELVNHSVPQPSCVPYNFLPMSILLIETNGSILYKEYEGMIAQSCTCR", "length": 392 }, "evidence": [ { "id": "A0A3L7H225", "url": "https://omabrowser.org/oma/group/A0A3L7H225/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H225", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H225" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H225", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H225" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H225", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H225" } ], "pmid": "" }, { "name": "growth factor activity", "id": "GO:0008083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008083", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H225", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H225" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 373, "end_pos": 375, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3L7H225", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H225" }, { "id": "PS51362", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51362" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TGF-beta family profile", "eco_id": "ECO_0000259", "start_pos": 264, "end_pos": 392, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 236, "end_pos": 238 }, { "start_pos": 349, "end_pos": 351 }, { "start_pos": 373, "end_pos": 375 }, { "start_pos": 85, "end_pos": 87 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027288285", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288285" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H367", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H367" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pdzd4", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H367", "locus": {} } ], "crossref": [ { "id": "cd06716", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06716", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100751172", "url": "https://www.ncbi.nlm.nih.gov/gene/100751172", "database": "GeneID", "categories": [ "Genome 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15545:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027288285", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288285", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7H367", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H367", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7H367-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H367-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M2D7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2D7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M2D7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2D7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K2A8", 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"MGCNMCVVQKPEEQYKVMLQVNGKELSKLSQEQTLEALRASKEPLVIQVLRRSPRLRGDSSCHDLQLVDSGTQTDITFEHIMALGKLRPPTPPMGILEPYVLSELPPISHEYYDPAEFMEGGPQEAERMDELEYEEVELCKNSHQDKLGLMVCYRTDDEEDLGIYVGEVNPNSIAAKDGRIREGDRIIQINGMDVQNREEAVAILSQEENTNISLLVARPESQLAKRWKDSDRDDFLDDFGSENEGDLRARKLKSPPAQQTENDEKGAPDGGPGLSNSQELDSGVGRTDDSTRNEESSEHDLLGDEPPSTTNTPGSLRKFGLQGDAMQSRDFHFSMDSLLAEGAGLGGADLPGLTDEEYERYRELLEIKCHLENGNQLSIFSRASSGNSALDVNRNESLGHEMAMLEEELRHLEFKCRNILRAQKMQQLRERCMKAWLLEEESLYDLAASEPKKHELSDISELPEKSDKDSTSAYNTGESCRSTPLLVEPLPESSLKRSTAGNSNLNRTPSGPPVTTHPKGAPSAKFRSLSRDPEVGRRQHTEERVRRSAKTGVTLERVGPEGSPYLSRRHHGQESEHYRSCVQLAPPRTLEDLGHGSLSLASGPRVGGVVAAAVETPRMEWKVKVRSDGTRYVAKRPVRDRLLKARALKIREERSGMTTDDDAVSEMKMGRYWSKEERKQHLIRAREQRKRREFMMQSRLECLREQQNGDSKPELNIIALSHRKTMKKRNKKILDNWITIQEMLAHGARSADGKRIYNPLLSVTTV", "length": 767, "header": "tr|A0A3L7H367-1|A0A3L7H367_CRIGR Isoform 1 of PDZ domain-containing protein 4 isoform X2 OS=Cricetulus griseus OX=10029 GN=Pdzd4 PE=4 SV=1 CANONICAL=A0A3L7H367-1" }, "isoforms": [ { "isoform_ac": "A0A3L7H367-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H367/entry#A0A3L7H367-1", "sequence": { "sequence": "MGCNMCVVQKPEEQYKVMLQVNGKELSKLSQEQTLEALRASKEPLVIQVLRRSPRLRGDSSCHDLQLVDSGTQTDITFEHIMALGKLRPPTPPMGILEPYVLSELPPISHEYYDPAEFMEGGPQEAERMDELEYEEVELCKNSHQDKLGLMVCYRTDDEEDLGIYVGEVNPNSIAAKDGRIREGDRIIQINGMDVQNREEAVAILSQEENTNISLLVARPESQLAKRWKDSDRDDFLDDFGSENEGDLRARKLKSPPAQQTENDEKGAPDGGPGLSNSQELDSGVGRTDDSTRNEESSEHDLLGDEPPSTTNTPGSLRKFGLQGDAMQSRDFHFSMDSLLAEGAGLGGADLPGLTDEEYERYRELLEIKCHLENGNQLSIFSRASSGNSALDVNRNESLGHEMAMLEEELRHLEFKCRNILRAQKMQQLRERCMKAWLLEEESLYDLAASEPKKHELSDISELPEKSDKDSTSAYNTGESCRSTPLLVEPLPESSLKRSTAGNSNLNRTPSGPPVTTHPKGAPSAKFRSLSRDPEVGRRQHTEERVRRSAKTGVTLERVGPEGSPYLSRRHHGQESEHYRSCVQLAPPRTLEDLGHGSLSLASGPRVGGVVAAAVETPRMEWKVKVRSDGTRYVAKRPVRDRLLKARALKIREERSGMTTDDDAVSEMKMGRYWSKEERKQHLIRAREQRKRREFMMQSRLECLREQQNGDSKPELNIIALSHRKTMKKRNKKILDNWITIQEMLAHGARSADGKRIYNPLLSVTTV", "length": 767, "header": "tr|A0A3L7H367-1|A0A3L7H367_CRIGR Isoform 1 of PDZ domain-containing protein 4 isoform X2 OS=Cricetulus griseus OX=10029 GN=Pdzd4 PE=4 SV=1 CANONICAL=A0A3L7H367-1" }, "locus": {} }, { "isoform_ac": "A0A8C2M2D7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H367/entry#A0A8C2M2D7-1", "sequence": { "sequence": "MGCNMCVVQKPEEQYKVMLQEVELCKNSHQDKLGLMVCYRTDDEEDLGIYVGEVNPNSIAAKDGRIREGDRIIQINGMDVQNREEAVAILSQEENTNISLLVARPESQLAKRWKDSDRDDFLDDFGSENEGDLRARKLKSPPAQQTENDEKGAPDGGPGLSNSQELDSGVGRTDDSTRNEESSEHDLLGDEPPSTTNTPGSLRKFGLQGDAMQSRDFHFSMDSLLAEGAGLGGADLPGLTDEEYERYRELLEIKCHLENGNQLSIFSRASSGNSALDVNRNESLGHEMAMLEEELRHLEFKCRNILRAQKMQQLRERCMKAWLLEEESLYDLAASEPKKHELSDISELPEKSDKDSTSAYNTGESCRSTPLLVEPLPESSLKRSTAGNSNLNRTPSGPPVTTHPKGAPSAKFRSLSRDPEVGRRQHTEERVRRSAKTGVTLERVGPEGSPYLSRRHHGQESEHYRSCVQLAPPRTLEDLGHGSLSLASGPRVGGVVAAAVETPRMEWKVKVRSDGTRYVAKRPVRDRLLKARALKIREERSGMTTDDDAVSEMKMGRYWSKEERKQHLIRAREQRKRREFMMQSRLECLREQQNGDSKPELNIIALSHRKTMKKRNKKILDNWITIQEMLAHGARSADGKRIYNPLLSVTTV", "length": 652, "header": "tr|A0A8C2M2D7-1|A0A8C2M2D7_CRIGR Computationally mapped isoform of PDZ domain-containing protein 4 isoform X4 OS=Cricetulus griseus OX=10029 GN=Pdzd4 PE=4 SV=1 CANONICAL=A0A3L7H367-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K2A8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H367/entry#A0A9J7K2A8-1", "sequence": { "sequence": "MGCNMCVVQKPEEQYKVMLQVNGKELSKLSQEQTLEALRASKEPLVIQVLRRSPRLRGDSSCHDLQLVDSGTQTDITFEHIMALGKLRPPTPPMGILEPPPISHEYYDPAEFMEGGPQEAERMDELEYEEVELCKNSHQDKLGLMVCYRTDDEEDLGIYVGEVNPNSIAAKDGRIREGDRIIQINGMDVQNREEAVAILSQEENTNISLLVARPESQLAKRWKDSDRDDFLDDFGSENEGDLRARKLKSPPAQQTENDEKGAPDGGPGLSNSQELDSGVGRTDDSTRNEESSEHDLLGDEPPSTTNTPGSLRKFGLQGDAMQSRDFHFSMDSLLAEGAGLGGADLPGLTDEEYERYRELLEIKCHLENGNQLSIFSRASSGNSALDVNRNESLGHEMAMLEEELRHLEFKCRNILRAQKMQQLRERCMKAWLLEEESLYDLAASEPKKHELSDISELPEKSDKDSTSAYNTGESCRSTPLLVEPLPESSLKRSTAGNSNLNRTPSGPPVTTHPKGAPSAKFRSLSRDPEVGRRQHTEERVRRSAKTGVTLERVGPEGSPYLSRRHHGQESEHYRSCVQLAPPRTLEDLGHGSLSLASGPRVGGVVAAAVETPRMEWKVKVRSDGTRYVAKRPVRDRLLKARALKIREERSGMTTDDDAVSEMKMGRYWSKEERKQHLIRAREQRKRREFMMQSRLECLREQQNGDSKPELNIIALSHRKTMKKRNKKILDNWITIQEMLAHGARSADGKRIYNPLLSVTTV", "length": 761, "header": "tr|A0A9J7K2A8-1|A0A9J7K2A8_CRIGR Computationally mapped isoform of PDZ domain-containing protein 4 isoform X3 OS=Cricetulus griseus OX=10029 GN=Pdzd4 PE=4 SV=1 CANONICAL=A0A3L7H367-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H367", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H367" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751172", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751172", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 396, "end_pos": 398, "annotation": "n_glycosylation_sequon" }, { "start_pos": 507, "end_pos": 509, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3L7H367", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H367" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 136, "end_pos": 221, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 212, "end_pos": 214 }, { "start_pos": 396, "end_pos": 398 }, { "start_pos": 507, "end_pos": 509 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. 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:: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027287077", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287077" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H6E4", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H6E4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113837367", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H6E4", "locus": {} } ], "crossref": [ { "id": "cd20268", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20268", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "113837367", "url": "https://www.ncbi.nlm.nih.gov/gene/113837367", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045295", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045295", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052687", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052687", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113837367", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113837367", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3L7H6E4", "url": "https://www.orthodb.org/?gene=A0A3L7H6E4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47046", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47046", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47046:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47046:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05347", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05347", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027287077", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287077", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7H6E4", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H6E4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7H6E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H6E4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRPSRLQRQILSLYRELLRAGRGKPGAEARVRAEFRQHAGLPRSDVLRIEYLYRRGKRQLQLLRSGHATAMGIFVRPRGPTEEAGGGTATPGPESPCGGTEARETRSGGR", "length": 111, "header": "tr|A0A3L7H6E4-1|A0A3L7H6E4_CRIGR Isoform 1 of Succinate dehydrogenase assembly factor 1, mitochondrial-like OS=Cricetulus griseus OX=10029 GN=LOC113837367 PE=3 SV=1 CANONICAL=A0A3L7H6E4-1" }, "isoforms": [ { "isoform_ac": "A0A3L7H6E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H6E4/entry#A0A3L7H6E4-1", "sequence": { "sequence": "MSRPSRLQRQILSLYRELLRAGRGKPGAEARVRAEFRQHAGLPRSDVLRIEYLYRRGKRQLQLLRSGHATAMGIFVRPRGPTEEAGGGTATPGPESPCGGTEARETRSGGR", "length": 111, "header": "tr|A0A3L7H6E4-1|A0A3L7H6E4_CRIGR Isoform 1 of Succinate dehydrogenase assembly factor 1, mitochondrial-like OS=Cricetulus griseus OX=10029 GN=LOC113837367 PE=3 SV=1 CANONICAL=A0A3L7H6E4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 82, "start_aa": "Thr", "end_pos": 82, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr82", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 91, "start_aa": "Thr", "end_pos": 91, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr91", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304453", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304453" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H6Z4", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H6Z4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ppp1r17", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H6Z4", "locus": {} } ], "crossref": [ { "id": "100750492", "url": "https://www.ncbi.nlm.nih.gov/gene/100750492", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR033242", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033242", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100750492", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750492", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LDPRCGH", "url": "https://omabrowser.org/oma/group/LDPRCGH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7H6Z4", "url": "https://www.orthodb.org/?gene=A0A3L7H6Z4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15387", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15387", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15387:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15387:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27915", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27915", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304453", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304453", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7H6Z4", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H6Z4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7H6Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H6Z4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATEMMATEPVQPLELSEDILDKFDPHCDSSDDLSDQFIKDCDLKKKPRKGKNVQATLNVESEQKKPRRKDTPALHIPPFIPGVISEHLIKRYDVQDRVPKVKTGSGLHNTDMEQKRPRRKDTPALHMPPFVAGLTLLGDESPRVIMEDDEKDGDKITI", "length": 159, "header": "tr|A0A3L7H6Z4-1|A0A3L7H6Z4_CRIGR Isoform 1 of Protein phosphatase 1 regulatory subunit 17 OS=Cricetulus griseus OX=10029 GN=Ppp1r17 PE=4 SV=1 CANONICAL=A0A3L7H6Z4-1" }, "isoforms": [ { "isoform_ac": "A0A3L7H6Z4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H6Z4/entry#A0A3L7H6Z4-1", "sequence": { "sequence": "MATEMMATEPVQPLELSEDILDKFDPHCDSSDDLSDQFIKDCDLKKKPRKGKNVQATLNVESEQKKPRRKDTPALHIPPFIPGVISEHLIKRYDVQDRVPKVKTGSGLHNTDMEQKRPRRKDTPALHMPPFVAGLTLLGDESPRVIMEDDEKDGDKITI", "length": 159, "header": "tr|A0A3L7H6Z4-1|A0A3L7H6Z4_CRIGR Isoform 1 of Protein phosphatase 1 regulatory subunit 17 OS=Cricetulus griseus OX=10029 GN=Ppp1r17 PE=4 SV=1 CANONICAL=A0A3L7H6Z4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H6Z4", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H6Z4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H6Z4", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H6Z4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100750492", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750492", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5NXN4-1", "protein_name": "Protein phosphatase 1 regulatory subunit 17", "gene_name": "PPP1R17", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MMSTECVQPLDIPEDRLDKRDSHCNHLEDLSEQLIKSCDLKKKPRKGKTIQPSQNAEQEQKKPRRKDTPAIHTPPPLTGILSDFSDNLLKRYGISEKPQRERVSQGSQITELEQKKPRRKDTPAIHIPPLIIGTKLLTEEKQTAIMEDEEKDGDTIPS", "length": 158 }, "evidence": [ { "id": "A0A3L7H6Z4", "url": "https://omabrowser.org/oma/group/A0A3L7H6Z4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1N1Q9-1", "protein_name": "Protein phosphatase 1 regulatory subunit 17", "gene_name": "PPP1R17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MMSTEQMQPLELSEDRLDKLDPRCSHLDDLSDQFIKDCDLKKKPIKGKNVQVTLNVESDQKKPRRKDTPALHVPPFIPDVLSEHLITRYDVQDIQPKGKMSPVLHNTDLEQKKPRRKDTPALHVSPFAAGVTLLRDERPKVIVEDDEKDGDKIAI", "length": 155 }, "evidence": [ { "id": "A0A3L7H6Z4", "url": "https://omabrowser.org/oma/group/A0A3L7H6Z4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O96001-1", "protein_name": "Protein phosphatase 1 regulatory subunit 17", "gene_name": "PPP1R17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMSTEQMQPLELSEDRLDKLDPRCSHLDDLSDQFIKDCDLKKKPRKGKNVQATLNVESDQKKPRRKDTPALHIPPFIPGVFSEHLIKRYDVQERHPKGKMIPVLHNTDLEQKKPRRKDTPALHMSPFAAGVTLLRDERPKAIVEDDEKDGDKIAI", "length": 155 }, "evidence": [ { "id": "A0A3L7H6Z4", "url": "https://omabrowser.org/oma/group/A0A3L7H6Z4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z2E4-1", "protein_name": "Protein phosphatase 1 regulatory subunit 17", "gene_name": "Ppp1r17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTEMMTTEPVPPLELSDDILGKLDPQCSPSDDLSDQFIKDCDLKKKPRKGKNVQATLNVESDQKKPRRKDTPAVHIPPFIPGVISEHLIKRYDVQERIPKAKSGPALHNSDMEQKRPRRKDTPALHMPPFVAGLTLLRDESAGVILEDEEMDGDKLAI", "length": 159 }, "evidence": [ { "id": "A0A3L7H6Z4", "url": "https://omabrowser.org/oma/group/A0A3L7H6Z4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein serine/threonine phosphatase inhibitor activity", "id": "GO:0004865", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004865", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H6Z4", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H6Z4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7H729-1", "uniprot_ac": "A0A3L7H729", "uniprot_id": "A0A3L7H729_CRIGR", "mass": { "chemical_mass": 12760.0, "monoisotopic_mass": 12760.0 }, "refseq": { "ac": "XP_003511182", "name": "39S ribosomal protein L53, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511182" }, "gene_names": [ { "name": "Mrpl53", "type": "recommended", "evidence": [ { "id": "A0A3L7H729", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H729" } ] }, { "name": "Mrpl53", "type": "synonym", "evidence": [ { "id": "XP_003511182", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511182" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein mL53", "type": "recommended", "evidence": [ { "id": "A0A3L7H729", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H729/entry#names_and_taxonomy" } ] }, { "name": "39S ribosomal protein L53, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_003511182", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511182" }, { "id": "A0A3L7H729", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H729/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615037.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003511182", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511182" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H729", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H729" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mrpl53", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H729", "locus": {} } ], "crossref": [ { "id": "100762073", "url": "https://www.ncbi.nlm.nih.gov/gene/100762073", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052473", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052473", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762073", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762073", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CKMWERI", "url": "https://omabrowser.org/oma/group/CKMWERI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7H729", "url": "https://www.orthodb.org/?gene=A0A3L7H729", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33618", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33618", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33618:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33618:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10780", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10780", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003511182", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511182", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7H729", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H729", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7H729-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H729-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASALARVGLKPVKLVRVQFCPFEKNVESTRTFLQAVSSEKVRATNLNCSVVADVRHDGSEPCVDVLFGDGYRLIMRSANLTAQEMFTALASHIRARNAAAASAAANADKPGPVNGTRR", "length": 119, "header": "tr|A0A3L7H729-1|A0A3L7H729_CRIGR Isoform 1 of Large ribosomal subunit protein mL53 OS=Cricetulus griseus OX=10029 GN=Mrpl53 PE=3 SV=1 CANONICAL=A0A3L7H729-1" }, "isoforms": [ { "isoform_ac": "A0A3L7H729-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H729/entry#A0A3L7H729-1", "sequence": { "sequence": "MASALARVGLKPVKLVRVQFCPFEKNVESTRTFLQAVSSEKVRATNLNCSVVADVRHDGSEPCVDVLFGDGYRLIMRSANLTAQEMFTALASHIRARNAAAASAAANADKPGPVNGTRR", "length": 119, "header": "tr|A0A3L7H729-1|A0A3L7H729_CRIGR Isoform 1 of Large ribosomal subunit protein mL53 OS=Cricetulus griseus OX=10029 GN=Mrpl53 PE=3 SV=1 CANONICAL=A0A3L7H729-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H729", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H729" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H729", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H729" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762073", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762073", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PKK3-1", "protein_name": "Large ribosomal subunit protein mL53", "gene_name": "MRPL53", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MASRIRVVLRPVKSIVVRFCPFESNVESTRKFLQCINHKRIQATNRNCEVSADVRHDGSEPLVDVMFADGERLIMKGANLTTVEMLTALGSRCNAKELKAEQKSKKNP", "length": 108 }, "evidence": [ { "id": "A0A3L7H729", "url": "https://omabrowser.org/oma/group/A0A3L7H729/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027286320", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286320" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H7N2", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H7N2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Nfkbib", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H7N2", "locus": {} } ], "crossref": [ { "id": "100769201", "url": "https://www.ncbi.nlm.nih.gov/gene/100769201", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769201", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769201", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3L7H7N2", "url": "https://www.orthodb.org/?gene=A0A3L7H7N2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47303", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47303", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47303:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47303:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027286320", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286320", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7H7N2", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H7N2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7H7N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H7N2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGVACLGKSADVDEWCDSGLGSLGPDAAAPGGPGLGAELGPELSWAPLVFGYVTEDGDTALHLAVIHQHEPFLDFLLGFSAGTEYLDLQNDLGQTALHLAAILGEASTVEKLYAAGAGVLVAERGGHTALHLACRVRAHTCACALLQPRPRRPRDVSDTYLTQSQDNTTDTGPTPVAVNPQPNPEIEEDPSDEDWKLQLEAENYEGHTPLHVAVIHKDAEMVRLLRDAGADLNKPEPTCGRTPLHLAVEAQAANVLELLLKAGADPTARMYGGRTPLGSALLRPNPILARLLRAHGAPEPEDEDDKLGPCSSSSSDSDSDGRDEGDEYDDIVVHSGRSQNWLPPSPAPKPLPDDSNPA", "length": 359, "header": "tr|A0A3L7H7N2-1|A0A3L7H7N2_CRIGR Isoform 1 of NF-kappa-B inhibitor beta isoform X2 OS=Cricetulus griseus OX=10029 GN=Nfkbib PE=4 SV=1 CANONICAL=A0A3L7H7N2-1" }, "isoforms": [ { "isoform_ac": "A0A3L7H7N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H7N2/entry#A0A3L7H7N2-1", "sequence": { "sequence": "MAGVACLGKSADVDEWCDSGLGSLGPDAAAPGGPGLGAELGPELSWAPLVFGYVTEDGDTALHLAVIHQHEPFLDFLLGFSAGTEYLDLQNDLGQTALHLAAILGEASTVEKLYAAGAGVLVAERGGHTALHLACRVRAHTCACALLQPRPRRPRDVSDTYLTQSQDNTTDTGPTPVAVNPQPNPEIEEDPSDEDWKLQLEAENYEGHTPLHVAVIHKDAEMVRLLRDAGADLNKPEPTCGRTPLHLAVEAQAANVLELLLKAGADPTARMYGGRTPLGSALLRPNPILARLLRAHGAPEPEDEDDKLGPCSSSSSDSDSDGRDEGDEYDDIVVHSGRSQNWLPPSPAPKPLPDDSNPA", "length": 359, "header": "tr|A0A3L7H7N2-1|A0A3L7H7N2_CRIGR Isoform 1 of NF-kappa-B inhibitor beta isoform X2 OS=Cricetulus griseus OX=10029 GN=Nfkbib PE=4 SV=1 CANONICAL=A0A3L7H7N2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 175, "start_aa": "Thr", "end_pos": 175, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr175", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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[], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 175 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 168, "end_pos": 170 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7H7R7-1", "uniprot_ac": "A0A3L7H7R7", "uniprot_id": "A0A3L7H7R7_CRIGR", "mass": { "chemical_mass": 21303.0, "monoisotopic_mass": 21303.0 }, "refseq": { "ac": "XP_003509276", "name": "killer cell lectin-like receptor subfamily G member 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509276" }, "gene_names": [ { "name": "Klrg1", "type": "recommended", "evidence": [ { "id": "A0A3L7H7R7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H7R7" } ] }, { "name": "Klrg1", "type": "synonym", "evidence": [ { "id": "XP_003509276", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509276" } ] } ], "protein_names": [ { "name": "Killer cell lectin-like receptor subfamily G member 1", "type": "synonym", "evidence": [ { "id": "A0A3L7H7R7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H7R7/entry#names_and_taxonomy" } ] }, { "name": "killer cell lectin-like receptor subfamily G member 1", "type": "synonym", "evidence": [ { "id": "XP_003509276", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509276" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 2% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614669.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003509276", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509276" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H7R7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H7R7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Klrg1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H7R7", "locus": {} } ], "crossref": [ { "id": "cd03593", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03593", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100761776", "url": "https://www.ncbi.nlm.nih.gov/gene/100761776", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761776", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761776", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SCPDFWM", "url": "https://omabrowser.org/oma/group/SCPDFWM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7H7R7", "url": "https://www.orthodb.org/?gene=A0A3L7H7R7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47648", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47648", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47648:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47648:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003509276", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509276", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7H7R7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H7R7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7H7R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H7R7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADSDIYCTLELPATPQVQEDSRSKLRALFRRLPLSCLVTVALGLLTVILVGLLMCQRIPCCGSKDSVCAHCPSCPNLWMRNGSHCYYFSTEKKDWNSSLEFCADKGSHLLMFLDDEEVIPFQKYLDNDFYWIGLRKTDGWRWEGGPILSLRIVSNSLIQTCGTIHKDGLQASSCEVPLRWICQKTTN", "length": 188, "header": "tr|A0A3L7H7R7-1|A0A3L7H7R7_CRIGR Isoform 1 of Killer cell lectin-like receptor subfamily G member 1 OS=Cricetulus griseus OX=10029 GN=Klrg1 PE=4 SV=1 CANONICAL=A0A3L7H7R7-1" }, "isoforms": [ { "isoform_ac": "A0A3L7H7R7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H7R7/entry#A0A3L7H7R7-1", "sequence": { "sequence": "MADSDIYCTLELPATPQVQEDSRSKLRALFRRLPLSCLVTVALGLLTVILVGLLMCQRIPCCGSKDSVCAHCPSCPNLWMRNGSHCYYFSTEKKDWNSSLEFCADKGSHLLMFLDDEEVIPFQKYLDNDFYWIGLRKTDGWRWEGGPILSLRIVSNSLIQTCGTIHKDGLQASSCEVPLRWICQKTTN", "length": 188, "header": "tr|A0A3L7H7R7-1|A0A3L7H7R7_CRIGR Isoform 1 of Killer cell lectin-like receptor subfamily G member 1 OS=Cricetulus griseus OX=10029 GN=Klrg1 PE=4 SV=1 CANONICAL=A0A3L7H7R7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H7R7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H7R7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H7R7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H7R7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761776", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761776", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1B8W2-1", "protein_name": "Killer cell lectin like receptor G1", "gene_name": "KLRG1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTDNVTYSIIKSSAARQALKDDRQQQEASSSRSPRSYHVAIALGLLSTILASMLLLQWILYRGSKCAGCPHCPDHWMGYGDHCYYFSVEKKSWNSSLEFCLAKDAHLLMFKDSKEMIELQNLLSQEFYWIGLRNSSGWRWEDGSALNISRIASNSLVQNCGTISKGGLLASSCEVDFPWVCKKVRR", "length": 186 }, "evidence": [ { "id": "A0A3L7H7R7", "url": "https://omabrowser.org/oma/group/A0A3L7H7R7/", "database": "OMA" } ], 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"MADNSIYSTLELPAAPRVQDDSRWKVKAVLHRPCVSYLVMVALGLLTVILMSLLLYQRTLCCGSKGFMCSQCSRCPNLWMRNGSHCYYFSMEKRDWNSSLKFCADKGSHLLTFPDNQGVNLFQEYVGEDFYWIGLRDIDGWRWEDGPALSLSILSNSVVQKCGTIHRCGLHASSCEVALQWICEKVLP", "length": 188 }, "evidence": [ { "id": "A0A3L7H7R7", "url": "https://omabrowser.org/oma/group/A0A3L7H7R7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96E93-1", "protein_name": "Killer cell lectin-like receptor subfamily G member 1", "gene_name": "KLRG1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDSVIYSMLELPTATQAQNDYGPQQKSSSSRPSCSCLVAIALGLLTAVLLSVLLYQWILCQGSNYSTCASCPSCPDRWMKYGNHCYYFSVEEKDWNSSLEFCLARDSHLLVITDNQEMSLLQVFLSEAFCWIGLRNNSGWRWEDGSPLNFSRISSNSFVQTCGAINKNGLQASSCEVPLHWVCKKCPFADQALF", "length": 195 }, "evidence": [ { "id": "A0A3L7H7R7", "url": "https://omabrowser.org/oma/group/A0A3L7H7R7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": 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"https://www.ncbi.nlm.nih.gov/protein/XP_003503614" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613981.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003503614", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503614" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H881", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H881" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Prokr1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H881", "locus": {} } ], "crossref": [ { "id": "cd15204", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15204", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100766220", "url": "https://www.ncbi.nlm.nih.gov/gene/100766220", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766220", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766220", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CAATNYL", "url": "https://omabrowser.org/oma/group/CAATNYL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7H881", "url": "https://www.orthodb.org/?gene=A0A3L7H881", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24238", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24238", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24238:SF74", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24238:SF74", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003503614", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503614", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7H881", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H881", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7H881-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H881-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPTVGALGENTTDTSTSFLSLVNARGAQAASFPFTLSYGDYDTALGEEEDVTKSWTFFAARIVIGMALVAIMLVCGVGNFIFITTLARYKKLRNLTNLLIANLAISDFLVAIVCCPFEMDYYVVRQLSWEHGHVLCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRPRMKCQTAAGLIFLVWSVSILIAIPAAYFTTETVLVIVESQEKIFCGQIWPVDQQVYYRSYFLLVFGLEFVGPVVAMTLCYARVSRELWFKAVPGFQTEQIRRRLRCRRRTVLGLVCVLSAYVLCWAPFYGFTIVRDFFPSVFVKEKHYLTAFYVVECIAMSNSMINTLCFVSVRNNTSKYLKRILRLQWRASPSGSKASADLDLRTTGMPATEEVDCIGLK", "length": 393, "header": "tr|A0A3L7H881-1|A0A3L7H881_CRIGR Isoform 1 of Prokineticin receptor 1 OS=Cricetulus griseus OX=10029 GN=Prokr1 PE=3 SV=1 CANONICAL=A0A3L7H881-1" }, "isoforms": [ { "isoform_ac": "A0A3L7H881-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H881/entry#A0A3L7H881-1", "sequence": { "sequence": "MEPTVGALGENTTDTSTSFLSLVNARGAQAASFPFTLSYGDYDTALGEEEDVTKSWTFFAARIVIGMALVAIMLVCGVGNFIFITTLARYKKLRNLTNLLIANLAISDFLVAIVCCPFEMDYYVVRQLSWEHGHVLCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRPRMKCQTAAGLIFLVWSVSILIAIPAAYFTTETVLVIVESQEKIFCGQIWPVDQQVYYRSYFLLVFGLEFVGPVVAMTLCYARVSRELWFKAVPGFQTEQIRRRLRCRRRTVLGLVCVLSAYVLCWAPFYGFTIVRDFFPSVFVKEKHYLTAFYVVECIAMSNSMINTLCFVSVRNNTSKYLKRILRLQWRASPSGSKASADLDLRTTGMPATEEVDCIGLK", "length": 393, "header": "tr|A0A3L7H881-1|A0A3L7H881_CRIGR Isoform 1 of Prokineticin receptor 1 OS=Cricetulus griseus OX=10029 GN=Prokr1 PE=3 SV=1 CANONICAL=A0A3L7H881-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H881", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H881" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766220", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766220", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8R416-1", "protein_name": "Prokineticin receptor 1", "gene_name": "Prokr1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"METTVGALGENTTDTFTDFFSALDGHEAQTGSLPFTFSYGDYDMPLDEEEDVTNSRTFFAAKIVIGMALVGIMLVCGIGNFIFITALARYKKLRNLTNLLIANLAISDFLVAIVCCPFEMDYYVVRQLSWEHGHVLCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRPRMKCQTAAGLIFLVWSVSILIAIPAAYFTTETVLVIVERQEKIFCGQIWPVDQQFYYRSYFLLVFGLEFVGPVVAMTLCYARVSRELWFKAVPGFQTEQIRRRLRCRRRTVLGLVCVLSAYVLCWAPFYGFTIVRDFFPSVFVKEKHYLTAFYVVECIAMSNSMINTLCFVTVRNNTSKYLKRILRLQWRASPSGSKASADLDLRTTGIPATEEVDCIRLK", "length": 393 }, "evidence": [ { "id": "A0A3L7H881", "url": "https://omabrowser.org/oma/group/A0A3L7H881/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H881", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H881" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "neuropeptide Y 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This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027284286", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284286" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H8K1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H8K1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Lrrc61", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H8K1", "locus": {} } ], "crossref": [ { "id": "100765423", "url": "https://www.ncbi.nlm.nih.gov/gene/100765423", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765423", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765423", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YWESWPT", "url": "https://omabrowser.org/oma/group/YWESWPT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7H8K1", "url": "https://www.orthodb.org/?gene=A0A3L7H8K1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18849", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18849", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18849:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18849:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027284286", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284286", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7H8K1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H8K1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7H8K1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H8K1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPSGEKPGEAEGLSITPQLLKSRSGEFALDSILLLKLRGLGLVDLGCLGECLSLEWLDLSGNALTHLGPLAPLNQLAVLNVSNNRLTGLEPLAACENLQSLNVAGNLLATPGQLQCLAGLQGLEYLRLRDPLARLSNPLCATPSYWAVVRELLPGLKVIDGERVSGRGSDLYQLCRDLDSSLRRSSSPGPIAIEAQLWVDPDYWESCPMQSSSILEEACRQFQDTLQECLDLDRQAGDSLAQAQQALSAAEATSSVVF", "length": 259, "header": "tr|A0A3L7H8K1-1|A0A3L7H8K1_CRIGR Isoform 1 of Leucine-rich repeat-containing protein 61 OS=Cricetulus griseus OX=10029 GN=Lrrc61 PE=4 SV=1 CANONICAL=A0A3L7H8K1-1" }, "isoforms": [ { "isoform_ac": "A0A3L7H8K1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H8K1/entry#A0A3L7H8K1-1", "sequence": { "sequence": "MEPSGEKPGEAEGLSITPQLLKSRSGEFALDSILLLKLRGLGLVDLGCLGECLSLEWLDLSGNALTHLGPLAPLNQLAVLNVSNNRLTGLEPLAACENLQSLNVAGNLLATPGQLQCLAGLQGLEYLRLRDPLARLSNPLCATPSYWAVVRELLPGLKVIDGERVSGRGSDLYQLCRDLDSSLRRSSSPGPIAIEAQLWVDPDYWESCPMQSSSILEEACRQFQDTLQECLDLDRQAGDSLAQAQQALSAAEATSSVVF", "length": 259, "header": "tr|A0A3L7H8K1-1|A0A3L7H8K1_CRIGR Isoform 1 of Leucine-rich repeat-containing protein 61 OS=Cricetulus griseus OX=10029 GN=Lrrc61 PE=4 SV=1 CANONICAL=A0A3L7H8K1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 111, "start_aa": "Thr", "end_pos": 111, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr111", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 143, "start_aa": "Thr", "end_pos": 143, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr143", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H8K1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H8K1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H8K1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H8K1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765423", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765423", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1ADD4-1", "protein_name": "Leucine rich repeat containing 61", "gene_name": "LRRC61", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "METQTEKGEDGEGTRITAQLLKASTGEFALESILLLKLRGRGIADLGCLGDCTNLEWLDLSGNAISQLGPLAGLKALAVLNLSRNRISSLEPLSSCESLQSLNLAGNQVSSLQQLRCLAGLRRLESLRLRDALGQLSNPVCATAAYRAALPELLPGLRDIDGERVSGRGSELFQLCQDLDSSLGHGPGPAAPRAAQPWVQAGFWEPPPLRRSSIVEEAYRQFGEALRECRELGRRADDTIAQAERALSGRADPGSYVF", "length": 258 }, "evidence": [ { "id": "A0A3L7H8K1", "url": "https://omabrowser.org/oma/group/A0A3L7H8K1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZA60-1", "protein_name": "Leucine-rich repeat-containing protein 61", "gene_name": "Lrrc61", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPPGEKPGEAEALIITPQLLKSHSGEFALDSILLLKLRGLGVVDLGCLGECLNLEWLDLSGNALTHLGPLASLHQLAVLNVSNNRLTGLEPLAACENLQSLNAAGNLLTNPGQLQCLAGLQGLEHLRLRDPLARLSNPLCVNPSYWAAVRELLPGLKVIDGERVSGRGSELYQLCRDLDSSLRSSTSLGPRAIEVQPWVEPGYWESWPIRSSSILEEACRQFQDTLQECLDLDRQASDSLAQAQQALRPAKTTSSFVF", "length": 259 }, "evidence": [ { "id": "A0A3L7H8K1", "url": "https://omabrowser.org/oma/group/A0A3L7H8K1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2T9T5-1", "protein_name": "Leucine-rich repeat-containing protein 61", "gene_name": "LRRC61", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": 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"https://omabrowser.org/oma/group/A0A3L7H8K1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BV99-1", "protein_name": "Leucine-rich repeat-containing protein 61", "gene_name": "LRRC61", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPPAEKPGEAGGLQITPQLLKSRTGEFSLESILLLKLRGLGLADLGCLGECLGLEWLDLSGNALTHLGPLASLRQLAVLNVSNNRLTGLEPLATCENLQSLNAAGNLLATPGQLQCLAGLPCLEYLRLRDPLARLSNPLCANPSYWAAVRELLPGLKVIDGERVIGRGSEFYQLCRDLDSSLRPSSSPGPRATEAQPWVEPGYWESWPSRSSSILEEACRQFQDTLQECWDLDRQASDSLAQAEQVLSSAGPTSSFVF", "length": 259 }, "evidence": [ { "id": "A0A3L7H8K1", "url": "https://omabrowser.org/oma/group/A0A3L7H8K1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H8K1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H8K1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "outer dynein arm assembly", "id": "GO:0036158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036158", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H8K1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H8K1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 111, 143 ], "snv_sites": [], "glycation_sites": [], 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Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027283721", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283721" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H972", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H972" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113836905", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H972", "locus": {} } ], "crossref": [ { "id": "113836905", "url": "https://www.ncbi.nlm.nih.gov/gene/113836905", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR043383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113836905", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113836905", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3L7H972", "url": "https://www.orthodb.org/?gene=A0A3L7H972", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28649", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28649", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28649:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28649:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27763", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27763", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027283721", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283721", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7H972", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H972", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7H972-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H972-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNASFLNHSGLEEAGGDARAALGNRSHGLGTWLDCCPGGAPLTASDGVPAGLEPDERSLWVSRVAQIAVLCVLSLTVVFGVFFLGCNLLIKSESMINFLMQERRPSKDVGAAILGLY", "length": 117, "header": "tr|A0A3L7H972-1|A0A3L7H972_CRIGR Isoform 1 of Reprimo-like protein OS=Cricetulus griseus OX=10029 GN=LOC113836905 PE=4 SV=1 CANONICAL=A0A3L7H972-1" }, "isoforms": [ { "isoform_ac": "A0A3L7H972-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H972/entry#A0A3L7H972-1", "sequence": { "sequence": "MNASFLNHSGLEEAGGDARAALGNRSHGLGTWLDCCPGGAPLTASDGVPAGLEPDERSLWVSRVAQIAVLCVLSLTVVFGVFFLGCNLLIKSESMINFLMQERRPSKDVGAAILGLY", "length": 117, "header": "tr|A0A3L7H972-1|A0A3L7H972_CRIGR Isoform 1 of Reprimo-like protein OS=Cricetulus griseus OX=10029 GN=LOC113836905 PE=4 SV=1 CANONICAL=A0A3L7H972-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"XP_003498307", "name": "enhancer of rudimentary homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498307" }, "gene_names": [ { "name": "LOC100768642", "type": "recommended", "evidence": [ { "id": "A0A3L7H9A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9A7" } ] }, { "name": "Erh", "type": "synonym", "evidence": [ { "id": "XP_003498307", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498307" }, { "id": "A0A3L7H9A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9A7" } ] } ], "protein_names": [ { "name": "Enhancer of rudimentary homolog", "type": "recommended", "evidence": [ { "id": "A0A3L7H9A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9A7/entry#names_and_taxonomy" } ] }, { "name": "enhancer of rudimentary homolog", "type": "synonym", "evidence": [ { "id": "XP_003498307", "database": "RefSeq", "url": 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This record is derived from a genomic sequence (NW_003613686.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003498307", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498307" } ] }, { "annotation": "May have a role in the cell cycle.", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H9A7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9A7#function" }, { "database": "UniProtKB", "id": "ARBA00003742", "url": "https://www.uniprot.org/uniprotkb/ARBA00003742#function" }, { "database": "UniProtKB", "id": "PIRNR016393", "url": "https://www.uniprot.org/uniprotkb/PIRNR016393#function" }, { "database": "UniProtKB", "id": "A0A9J7JEQ2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JEQ2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H9A7", "url": 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"Enzyme and Pathway" ] }, { "id": "cge:100768642", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768642", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ESRTWSD", "url": "https://omabrowser.org/oma/group/ESRTWSD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7H9A7", "url": "https://www.orthodb.org/?gene=A0A3L7H9A7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JEQ2", "url": "https://www.orthodb.org/?gene=A0A9J7JEQ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12373", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12373", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12373:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12373:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01133", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01133", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003498307", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498307", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7H9A7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9A7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7H9A7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9A7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JEQ2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JEQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JEQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JEQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSHTILLVQPTKRPEGRTYADYESVNECMEGVCKMYEEHLKRMNPNSPSITYDISQLFDFIDDLADLSCLVYRADTQTYQPYNKDWIKEKIYVLLRRQAQQAGK", "length": 104, "header": "tr|A0A3L7H9A7-1|A0A3L7H9A7_CRIGR 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CANONICAL=A0A3L7H9A7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027283542", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283542" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H9B3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9B3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100769462", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9B3", "locus": {} } ], "crossref": [ { "id": "100769462", "url": "https://www.ncbi.nlm.nih.gov/gene/100769462", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002957", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002957", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769462", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769462", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3L7H9B3", "url": "https://www.orthodb.org/?gene=A0A3L7H9B3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23239", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23239", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23239:SF215", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23239:SF215", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027283542", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283542", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7H9B3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9B3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7H9B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9B3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLRFSGGSRHVGLQSGSLRPSSVGAGFAGSNAGGSSAAGSGFSWALGGPLSSAPGGSHATGTLGNAAGVGFVGNEGGLLSGNEKVTMQNLNNRLASYLDSVKALEEANAELERQIKNWHEKYGPGSCRGLDQDYSQYHLTIEDLKSKIISSTAANANIILQIDNARLAADDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEELTYLKKNHEEEMKVLQCAAGGNVNVEMNAAPSVDLTALLNNMRAEYEALAEQNRKDAEAGFQEKSATLQQQISNDMGAVTSARTELTELKRSLQTLEIELQSLSATKHSLECSLAETEGNYCSQLAHIQAQISALEEQLHQVRTETEGQKLEHEQLMDIKAHLEKEIETYCRLIDGDENSCSNFESGSSGNSSKDLSKTTLVKAVVEEIDQRGKVLSSRIHSIEEKMSKISNGKADQRAPF", "length": 459, "header": "tr|A0A3L7H9B3-1|A0A3L7H9B3_CRIGR Isoform 1 of Keratin, type I cytoskeletal 28 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100769462 PE=4 SV=1 CANONICAL=A0A3L7H9B3-1" }, "isoforms": [ { "isoform_ac": "A0A3L7H9B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9B3/entry#A0A3L7H9B3-1", "sequence": { "sequence": "MSLRFSGGSRHVGLQSGSLRPSSVGAGFAGSNAGGSSAAGSGFSWALGGPLSSAPGGSHATGTLGNAAGVGFVGNEGGLLSGNEKVTMQNLNNRLASYLDSVKALEEANAELERQIKNWHEKYGPGSCRGLDQDYSQYHLTIEDLKSKIISSTAANANIILQIDNARLAADDFRLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEELTYLKKNHEEEMKVLQCAAGGNVNVEMNAAPSVDLTALLNNMRAEYEALAEQNRKDAEAGFQEKSATLQQQISNDMGAVTSARTELTELKRSLQTLEIELQSLSATKHSLECSLAETEGNYCSQLAHIQAQISALEEQLHQVRTETEGQKLEHEQLMDIKAHLEKEIETYCRLIDGDENSCSNFESGSSGNSSKDLSKTTLVKAVVEEIDQRGKVLSSRIHSIEEKMSKISNGKADQRAPF", "length": 459, "header": "tr|A0A3L7H9B3-1|A0A3L7H9B3_CRIGR Isoform 1 of Keratin, type I cytoskeletal 28 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100769462 PE=4 SV=1 CANONICAL=A0A3L7H9B3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H9B3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9B3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H9B3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9B3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769462", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769462", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "epithelial cell differentiation", "id": "GO:0030855", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030855", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H9B3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9B3" } ], "pmid": "" }, { "name": "intermediate filament organization", "id": "GO:0045109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045109", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H9B3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9B3" } ], "pmid": "" }, { "name": "hair follicle morphogenesis", "id": "GO:0031069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031069", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H9B3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9B3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "intermediate filament", "id": "GO:0005882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H9B3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9B3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H9B3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9B3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 409, "end_pos": 411, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3L7H9B3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9B3" }, { "id": "PS51842", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51842" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IF rod", "eco_id": "ECO_0000259", "start_pos": 84, "end_pos": 399, "start_aa": "Glu", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 409, "end_pos": 411 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": 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"publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7H9G9-1", "uniprot_ac": "A0A3L7H9G9", "uniprot_id": "A0A3L7H9G9_CRIGR", "mass": { "chemical_mass": 69953.0, "monoisotopic_mass": 69953.0 }, "refseq": { "ac": "XP_003506614", "name": "tetratricopeptide repeat protein 39B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506614" }, "gene_names": [ { "name": "LOC100756657", "type": "recommended", "evidence": [ { "id": "A0A3L7H9G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9G9" } ] }, { "name": "LOC100756657", "type": "synonym", "evidence": [ { "id": "XP_003506614", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506614" } ] } ], "protein_names": [ { "name": "Tetratricopeptide repeat protein 39B", "type": "synonym", "evidence": [ { "id": "A0A3L7H9G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9G9/entry#names_and_taxonomy" } ] }, { "name": "tetratricopeptide repeat protein 39B", "type": "synonym", "evidence": [ { "id": "XP_003506614", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506614" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614257.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003506614", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506614" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H9G9", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9G9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100756657", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9G9", "locus": {} } ], "crossref": [ { "id": "100756657", "url": "https://www.ncbi.nlm.nih.gov/gene/100756657", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756657", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756657", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CIFTQNE", "url": "https://omabrowser.org/oma/group/CIFTQNE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7H9G9", "url": "https://www.orthodb.org/?gene=A0A3L7H9G9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31859", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31859", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31859:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31859:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10300", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10300", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003506614", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506614", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7H9G9", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9G9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7H9G9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9G9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRFLRNEDNEDNMLTMSVSLSEGESDRMARVTRSLSLRESEPEEKFEDAHEIIPVATTMNLLSSLEECTTGLYLFLNNRFSDAISLIHPWSNNSPYHALIYSMLMIVKAILTFEPQDIQIGMNAAKEALKTCNNFRKRPRIMTLSRLVSRQGIRSIKEEELHAEVCYAECLILKSAITFIQDDSLLNFLKSGINVGSSYQIYKDCQQVLELMPDNQSKTHRHLDGGVKFGLGVFNLMFSLVPPKSLKLLNIVGYSGDREVGLALLHESASEPHINNILSVFTLLFYYNYVRVAVGVEKVSTSATESLFLIYLEKFPNCVVLKFFRARFSMLNGNFETAQLKLQECIITQNEWKQVHHLCYWELMWCHIFLQNWRQAFNYANLLSQHSRWSKAIYTYSKAIIMALLPPNFVNSENESMSSIFLQVDNLRIKFLGSSVPIEKFIAEKSQRYGTTTGWFTAQPLLEFIYAWSGFRVMSKKIELISSWLSIIDKGKDLLNENPNEEYGTDDMSLLNLLKGLCLKHLGKHLKAEHYFIRVIKKEKMLKYDRYLVPYSYYELGMLHYLKGDYASATKNLDNIKNYKNYSMEARLQFRAHIALEQIAKLEK", "length": 605, "header": "tr|A0A3L7H9G9-1|A0A3L7H9G9_CRIGR Isoform 1 of Tetratricopeptide repeat protein 39B OS=Cricetulus griseus OX=10029 GN=LOC100756657 PE=3 SV=1 CANONICAL=A0A3L7H9G9-1" }, "isoforms": [ { "isoform_ac": "A0A3L7H9G9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9G9/entry#A0A3L7H9G9-1", "sequence": { "sequence": "MSRFLRNEDNEDNMLTMSVSLSEGESDRMARVTRSLSLRESEPEEKFEDAHEIIPVATTMNLLSSLEECTTGLYLFLNNRFSDAISLIHPWSNNSPYHALIYSMLMIVKAILTFEPQDIQIGMNAAKEALKTCNNFRKRPRIMTLSRLVSRQGIRSIKEEELHAEVCYAECLILKSAITFIQDDSLLNFLKSGINVGSSYQIYKDCQQVLELMPDNQSKTHRHLDGGVKFGLGVFNLMFSLVPPKSLKLLNIVGYSGDREVGLALLHESASEPHINNILSVFTLLFYYNYVRVAVGVEKVSTSATESLFLIYLEKFPNCVVLKFFRARFSMLNGNFETAQLKLQECIITQNEWKQVHHLCYWELMWCHIFLQNWRQAFNYANLLSQHSRWSKAIYTYSKAIIMALLPPNFVNSENESMSSIFLQVDNLRIKFLGSSVPIEKFIAEKSQRYGTTTGWFTAQPLLEFIYAWSGFRVMSKKIELISSWLSIIDKGKDLLNENPNEEYGTDDMSLLNLLKGLCLKHLGKHLKAEHYFIRVIKKEKMLKYDRYLVPYSYYELGMLHYLKGDYASATKNLDNIKNYKNYSMEARLQFRAHIALEQIAKLEK", "length": 605, "header": "tr|A0A3L7H9G9-1|A0A3L7H9G9_CRIGR Isoform 1 of Tetratricopeptide repeat protein 39B OS=Cricetulus griseus OX=10029 GN=LOC100756657 PE=3 SV=1 CANONICAL=A0A3L7H9G9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H9G9", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9G9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NW_003614074.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003504595", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504595" } ] }, { "annotation": "Might act as an inhibitor of spontaneous calcium carbonate precipitation.", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H9H0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9H0#function" }, { "database": "UniProtKB", "id": "ARBA00055730", "url": "https://www.uniprot.org/uniprotkb/ARBA00055730#function" }, { "database": "UniProtKB", "id": "A0A9J7H427", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H427#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H9H0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H9H0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", 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This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_003613631.1) and transcript sequence (IACG01091472.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003496753.1. 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This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027279039", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279039" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HCK9", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HCK9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Fam209a", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HCK9", "locus": {} } ], "crossref": [ { "id": "113836480", "url": "https://www.ncbi.nlm.nih.gov/gene/113836480", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113836480", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113836480", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PPGLRCF", "url": "https://omabrowser.org/oma/group/PPGLRCF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7HCK9", "url": "https://www.orthodb.org/?gene=A0A3L7HCK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35157", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35157", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35157:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35157:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15206", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15206", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027279039", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279039", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HCK9", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HCK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HCK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HCK9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRTLRWFLFLPLCISCACAFMFSSLREKNKESPGKVPCGGHFRIRQNLPEHTQGWLGSKWLWLFFVIMIYAMLKLRGDGEKNKEQNSTSLRGCQFRSPPKKNQNISPSKDFTFNTLTQLEMELVKFVSKVRNLKVSMATSSNPRLQIPDIPMGPHNNVTIYEIWGEEEPE", "length": 170, "header": "tr|A0A3L7HCK9-1|A0A3L7HCK9_CRIGR Isoform 1 of Protein FAM209A OS=Cricetulus griseus OX=10029 GN=Fam209a PE=4 SV=1 CANONICAL=A0A3L7HCK9-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HCK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HCK9/entry#A0A3L7HCK9-1", "sequence": { "sequence": "MRTLRWFLFLPLCISCACAFMFSSLREKNKESPGKVPCGGHFRIRQNLPEHTQGWLGSKWLWLFFVIMIYAMLKLRGDGEKNKEQNSTSLRGCQFRSPPKKNQNISPSKDFTFNTLTQLEMELVKFVSKVRNLKVSMATSSNPRLQIPDIPMGPHNNVTIYEIWGEEEPE", "length": 170, "header": "tr|A0A3L7HCK9-1|A0A3L7HCK9_CRIGR Isoform 1 of Protein FAM209A OS=Cricetulus griseus OX=10029 GN=Fam209a PE=4 SV=1 CANONICAL=A0A3L7HCK9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035302493", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302493" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HCU9", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HCU9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Spint3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HCU9", "locus": {} } ], "crossref": [ { "id": "cd00109", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00109", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "118239068", "url": "https://www.ncbi.nlm.nih.gov/gene/118239068", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002223", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002223", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020901", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020901", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036880", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036880", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:118239068", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:118239068", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VCAFPME", "url": "https://omabrowser.org/oma/group/VCAFPME/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7HCU9", "url": "https://www.orthodb.org/?gene=A0A3L7HCU9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10083", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10083", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10083:SF376", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10083:SF376", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00014", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00014", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035302493", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302493", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HCU9", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HCU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HCU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HCU9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQLQASLSFFLILVFCQHLYSEPNQVSRKPLPSICNLPMDKGACRALMVRWYYNTKSGKCVKFNYGGCGGNENNFLSRDQCRLACRRA", "length": 88, "header": "tr|A0A3L7HCU9-1|A0A3L7HCU9_CRIGR Isoform 1 of Kunitz-type protease inhibitor 3 OS=Cricetulus griseus OX=10029 GN=Spint3 PE=4 SV=1 CANONICAL=A0A3L7HCU9-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HCU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HCU9/entry#A0A3L7HCU9-1", "sequence": { "sequence": "MQLQASLSFFLILVFCQHLYSEPNQVSRKPLPSICNLPMDKGACRALMVRWYYNTKSGKCVKFNYGGCGGNENNFLSRDQCRLACRRA", "length": 88, "header": "tr|A0A3L7HCU9-1|A0A3L7HCU9_CRIGR Isoform 1 of Kunitz-type protease inhibitor 3 OS=Cricetulus griseus OX=10029 GN=Spint3 PE=4 SV=1 CANONICAL=A0A3L7HCU9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035302502", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302502" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HCY2", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HCY2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Gtsf1l", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HCY2", "locus": {} } ], "crossref": [ { "id": "100772957", "url": "https://www.ncbi.nlm.nih.gov/gene/100772957", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR022776", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022776", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772957", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772957", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DDPQQTF", "url": "https://omabrowser.org/oma/group/DDPQQTF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7HCY2", "url": "https://www.orthodb.org/?gene=A0A3L7HCY2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21402", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21402", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21402:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21402:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05253", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05253", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035302502", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302502", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HCY2", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HCY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HCY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HCY2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPESIEICPYNPHHRIPLSRFQYHLASCRKKNPKKAKKMASCKYNACHVVPIRKLAEHEATCVNRSSMEEEDTLSPLHVSLPQPQNEDTLQVRWLSNPDTWNVDSANCHPMFVLKSFVPQKLVCESDTQESQRDQPLEDPQSRTRRANL", "length": 150, "header": "tr|A0A3L7HCY2-1|A0A3L7HCY2_CRIGR Isoform 1 of Gametocyte-specific factor 1-like OS=Cricetulus griseus OX=10029 GN=Gtsf1l PE=4 SV=1 CANONICAL=A0A3L7HCY2-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HCY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HCY2/entry#A0A3L7HCY2-1", "sequence": { "sequence": "MEPESIEICPYNPHHRIPLSRFQYHLASCRKKNPKKAKKMASCKYNACHVVPIRKLAEHEATCVNRSSMEEEDTLSPLHVSLPQPQNEDTLQVRWLSNPDTWNVDSANCHPMFVLKSFVPQKLVCESDTQESQRDQPLEDPQSRTRRANL", "length": 150, "header": "tr|A0A3L7HCY2-1|A0A3L7HCY2_CRIGR Isoform 1 of Gametocyte-specific factor 1-like OS=Cricetulus griseus OX=10029 GN=Gtsf1l PE=4 SV=1 CANONICAL=A0A3L7HCY2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7HCY4-1", "uniprot_ac": "A0A3L7HCY4", "uniprot_id": "A0A3L7HCY4_CRIGR", "mass": { "chemical_mass": 18836.0, "monoisotopic_mass": 18836.0 }, "refseq": { "ac": "XP_027279791", "name": "UBA-like domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279791" }, "gene_names": [ { "name": "Ubald1", "type": "recommended", "evidence": [ { "id": "A0A3L7HCY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HCY4" } ] }, { "name": 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computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027279791", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279791" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HCY4", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HCY4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ubald1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HCY4", "locus": {} } ], "crossref": [ { "id": "cd14343", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14343", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100773153", "url": "https://www.ncbi.nlm.nih.gov/gene/100773153", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039310", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039310", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773153", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773153", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR31993", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31993", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31993:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31993:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF22566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027279791", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279791", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HCY4", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HCY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HCY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HCY4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVNMDELKHQVMINQFVLTAGCAADQAKQLLQAAHWQFETALSAFFQETNIPYSHHHQMMCTPANTPATPPNFPDALTMFSRLKASESFHGGGSSGSPMATSATSPPPHFPNATGSFATPSWPTAASPPGGPQHHQPQPPLWTPAPPSPASDWPPLAPQQATSEPRAHPAMEAER", "length": 176, "header": "tr|A0A3L7HCY4-1|A0A3L7HCY4_CRIGR Isoform 1 of UBA-like domain-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Ubald1 PE=3 SV=1 CANONICAL=A0A3L7HCY4-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HCY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HCY4/entry#A0A3L7HCY4-1", "sequence": { "sequence": "MSVNMDELKHQVMINQFVLTAGCAADQAKQLLQAAHWQFETALSAFFQETNIPYSHHHQMMCTPANTPATPPNFPDALTMFSRLKASESFHGGGSSGSPMATSATSPPPHFPNATGSFATPSWPTAASPPGGPQHHQPQPPLWTPAPPSPASDWPPLAPQQATSEPRAHPAMEAER", "length": 176, "header": "tr|A0A3L7HCY4-1|A0A3L7HCY4_CRIGR Isoform 1 of UBA-like domain-containing protein 1 OS=Cricetulus griseus OX=10029 GN=Ubald1 PE=3 SV=1 CANONICAL=A0A3L7HCY4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 120, "start_aa": "Thr", "end_pos": 120, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr120", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 70, "start_aa": "Thr", "end_pos": 70, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr70", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NW_003616080.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003513755.2. 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This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027278651", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278651" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HD44", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HD44" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tmem203", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HD44", "locus": {} } ], "crossref": [ { "id": "cd22816", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22816", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100750734", "url": "https://www.ncbi.nlm.nih.gov/gene/100750734", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019396", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019396", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100750734", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750734", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3L7HD44", "url": "https://www.orthodb.org/?gene=A0A3L7HD44", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13568", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13568", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13568:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13568:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_027278651", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027278651", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HD44", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HD44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HD44-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HD44-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLFSLRELVQWLGFATFEIFVHLLALLVFSVLLALRVDGLAPGLSWWNVFVPFFAADGLSTYFTTIVSVRLFQDGEKRLAVLRLFWVLTVLSLKFVFEMLLCQKLVEQTRELWFGLITSPVFILLQLLMIRACRVN", "length": 136, "header": "tr|A0A3L7HD44-1|A0A3L7HD44_CRIGR Isoform 1 of Transmembrane protein 203 isoform X2 OS=Cricetulus griseus OX=10029 GN=Tmem203 PE=4 SV=1 CANONICAL=A0A3L7HD44-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HD44-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HD44/entry#A0A3L7HD44-1", "sequence": { "sequence": "MLFSLRELVQWLGFATFEIFVHLLALLVFSVLLALRVDGLAPGLSWWNVFVPFFAADGLSTYFTTIVSVRLFQDGEKRLAVLRLFWVLTVLSLKFVFEMLLCQKLVEQTRELWFGLITSPVFILLQLLMIRACRVN", "length": 136, "header": "tr|A0A3L7HD44-1|A0A3L7HD44_CRIGR Isoform 1 of Transmembrane protein 203 isoform X2 OS=Cricetulus griseus OX=10029 GN=Tmem203 PE=4 SV=1 CANONICAL=A0A3L7HD44-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"evidence": [ { "database": "UniProtKB", "id": "A0A3L7HD44", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HD44" } ], "pmid": "" }, { "name": "intracellular calcium ion homeostasis", "id": "GO:0006874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006874", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HD44", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HD44" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": 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], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7HDH6-1", "uniprot_ac": "A0A3L7HDH6", "uniprot_id": "A0A3L7HDH6_CRIGR", "mass": { "chemical_mass": 56447.0, "monoisotopic_mass": 56447.0 }, "refseq": { "ac": "XP_003514714", "name": "UDP-N-acetylhexosamine pyrophosphorylase-like protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514714" }, "gene_names": [ { "name": "Uap1l1", "type": "recommended", "evidence": [ { "id": "A0A3L7HDH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HDH6" } ] }, { "name": "Uap1l1", "type": "synonym", "evidence": [ { "id": "XP_003514714", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514714" } ] } ], "protein_names": [ { "name": "UDP-N-acetylhexosamine pyrophosphorylase-like protein 1", "type": "recommended", "evidence": [ { "id": "A0A3L7HDH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HDH6/entry#names_and_taxonomy" } ] }, { "name": "UDP-N-acetylhexosamine pyrophosphorylase-like protein 1", "type": "synonym", "evidence": [ { "id": "XP_003514714", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514714" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616838.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003514714", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514714" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HDH6", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HDH6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Uap1l1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HDH6", "locus": {} } ], "crossref": [ { "id": "cd04193", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04193", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100771350", "url": "https://www.ncbi.nlm.nih.gov/gene/100771350", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002618", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002618", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039741", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039741", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771350", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771350", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "THCTVPW", "url": "https://omabrowser.org/oma/group/THCTVPW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7HDH6", "url": "https://www.orthodb.org/?gene=A0A3L7HDH6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11952", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11952", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11952:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11952:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01704", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01704", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003514714", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514714", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HDH6", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HDH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HDH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HDH6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASEQDVRAQLQRAGQEHLLRFWADLAPEPLAALLAELATLEPDALREHCQRAAAACALTPGPLADLAARLQPLPPECVGSAIRCDQETRLRWEEEGFRQIALNKVAVLLLAGGQGTRLGVTYPKGMYQVGLPSQKTLYQLQAERIRRVQQLAGQRLGTHCTVPWYIMTSEFTLGPTIKFFKEHDFFHLDPANVVLFEQRMLPAVTFEGKAILERKDKVAMAPDGNGGLYCALADHQILEDMKRRGVEFVHVYCVDNILVRLADPVFIGFCVLRGADCGAKVVEKAYPEEPVGVVCQVDGVPQVVEYSEISPETAGLRGPDGGLLYNTGNICNHFFTRDFLDKVTREFEPLLKLHVAVKKVPYVDEEGNLVKPLKPNGIKMEKFVFDVFQFAKNFVAFEVSREEEFSPLKNADTASRDNPSTSRRALLAQHYRWALQAGAHFLDVHGVQLPQQSGLLPNGDPPAICEISPLVSYSGEGLEMYLQGRKLQSPFILDEDQARLLQPQEC", "length": 507, "header": "tr|A0A3L7HDH6-1|A0A3L7HDH6_CRIGR Isoform 1 of UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 OS=Cricetulus griseus OX=10029 GN=Uap1l1 PE=3 SV=1 CANONICAL=A0A3L7HDH6-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HDH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HDH6/entry#A0A3L7HDH6-1", "sequence": { "sequence": "MASEQDVRAQLQRAGQEHLLRFWADLAPEPLAALLAELATLEPDALREHCQRAAAACALTPGPLADLAARLQPLPPECVGSAIRCDQETRLRWEEEGFRQIALNKVAVLLLAGGQGTRLGVTYPKGMYQVGLPSQKTLYQLQAERIRRVQQLAGQRLGTHCTVPWYIMTSEFTLGPTIKFFKEHDFFHLDPANVVLFEQRMLPAVTFEGKAILERKDKVAMAPDGNGGLYCALADHQILEDMKRRGVEFVHVYCVDNILVRLADPVFIGFCVLRGADCGAKVVEKAYPEEPVGVVCQVDGVPQVVEYSEISPETAGLRGPDGGLLYNTGNICNHFFTRDFLDKVTREFEPLLKLHVAVKKVPYVDEEGNLVKPLKPNGIKMEKFVFDVFQFAKNFVAFEVSREEEFSPLKNADTASRDNPSTSRRALLAQHYRWALQAGAHFLDVHGVQLPQQSGLLPNGDPPAICEISPLVSYSGEGLEMYLQGRKLQSPFILDEDQARLLQPQEC", "length": 507, "header": "tr|A0A3L7HDH6-1|A0A3L7HDH6_CRIGR Isoform 1 of UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 OS=Cricetulus griseus OX=10029 GN=Uap1l1 PE=3 SV=1 CANONICAL=A0A3L7HDH6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HDH6", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HDH6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771350", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771350", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AAG0-1", "protein_name": "UDP-N-acetylhexosamine pyrophosphorylase-like protein 1", "gene_name": "UAP1L1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTSERDVRARLQRAGQEHLLRFCAELAPGPRAALLAQLEPLEPEALREHCRRAADACARPPGPPPDLAARLRPLPPERVGSAIGGDPETLRLWEEEGFHQIALNKVAVLLLAGGQGTRLGVAYPKGMYQVGLPSRKTLYQLQAERIRRVEQLAGEHYGTRCTVPWYIMTSEFTLGPTAKFFKEHDFFHLDPDNVVMFEQRMLPAVTFDGKAILEQKDKVAMAPDGNGGLYCALADNQILEDMERRGVEFVHVYCVDNILVRLADPVFIGFCVLRGADCGAKVVEKAYPEEPVGVVCQVDGVPQVVEYSEISPETARRRAPGGGLLYNAGNICNHFFTRDFLQRVTRELEPLLKPHVAVKKVPYVDEEGTPVKPLEPNGIKMEKFVFDVLPFAKNFVAFQVLREDEFSPLKNADSADRDNPSTARRALLTQHYRWALQAGAHFLDAHGARLPEKPSLPSSGEPPAICEISPLVSYSGEGLEVYLQGREFGSPLILDENQARALKP", "length": 504 }, "evidence": [ { "id": "A0A3L7HDH6", "url": "https://omabrowser.org/oma/group/A0A3L7HDH6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V1AFW1-1", "protein_name": "UDP-N-acetylglucosamine pyrophosphorylase 1 like 1", "gene_name": "UAP1L1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEPPEEVRARLERAGQGHLLRFWAELDPAQRAELLAALPPGLGEHCRLAAACARPRERLERLDGRVEPLPAAVLGSVRHCGPAALQRWEDEGLHQISQNKVAVLLLAGGQGTRLGVSYPKGMYNVGLPSGKTLYQIQAERIRKVEQLAGQRHHCKCTIPWYIMTSEFTLGPTEEFFVKHSYFNLDKANVIMFEQRMLPAVTFDGKAILEEKGKIAMAPDGNGGLYRALVDNKILDDMKQRGIQYVHVYCVDNILVKMADPVFIGFCVAKGADCGAKVVEKAYPTEPIGVVCRVDGVSHVVVEYSEISPETAQQRRPDGGLMYSVGNICNHFFTVEFLQTVAQKHESQLKHHVAIKKVPYIDEEGNLVKPLKPNGIKLEKFVFDVFQFSKNFVAFEVLREEEFSPLKNADTAETDNPTTARQSLLAQHYRWALKAGARFLDEDGCRIPEKLSLSGTEDPPAVCEISPLVSYFGEGLEAYMKNKDFCSPFILDEDKAEMLRSC", "length": 501 }, "evidence": [ { "id": "A0A3L7HDH6", "url": "https://omabrowser.org/oma/group/A0A3L7HDH6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O64765-1", "protein_name": "UDP-N-acetylglucosamine diphosphorylase 2", "gene_name": "GLCNAC1PUT2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKEPTTEIEIETSAVATILPPPLPPTASPHQALVERLKDYGQEDVFSLWDELSPEERDLLLRDIENLDLPRIDRIIRCSLHSQGLPVAAIEPVPENCVSTVEERTKEDREKWWKMGLKAIYEGKLGVVLLSGGQGTRLGSSDPKGCYNIGLPSGKSLFQIQAERILCVQRLASQAMSEASPTRPVTIQWYIMTSPFTHEPTQKFFKSHKYFGLEPDQVTFFQQGTLPCISKDGKFIMETPFSLSKAPDGNGGVYTALKSSRLLEDMASRGIKYVDCYGVDNVLVRVADPTFLGYFIDKSAASAAKVVRKAYPQEKVGVFVRRGKGGPLTVVEYTELDQSMASATNQQTGRLQYCWSNVCLHMFTLDFLNQVANGLEKDSVYHLAEKKIPSINGDIVGLKLEQFIFDCFPYAPSTALFEVLREEEFAPVKNANGSNYDTPESARLLVLRLHTRWVIAAGGFLTHSVPLYATGVEVSPLCSYAGENLEAICRGRTFHAPCEISL", "length": 502 }, "evidence": [ { "id": "A0A3L7HDH6", "url": "https://omabrowser.org/oma/group/A0A3L7HDH6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q3KQV9-1", "protein_name": "UDP-N-acetylhexosamine pyrophosphorylase-like protein 1", "gene_name": "UAP1L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"MDSERDVRAQLQRAGQDHLLRFYADLAPEARAALLAELASLEADALREHCQRAAAAGALAPGPLPDLAARLQPLPPERVGSAIRCDQETRLRWEEEGFRQISLNKVAVLLLAGGQGTRLGVTYPKGMYQVGLPSQKTLYQLQAERIRRVQQLADQRQGTHCTVPWYIMTSEFTLGPTIKFFKEHDFFHLDPTNVVLFEQRMLPAVTFEGKAILERKDKVAMAPDGNGGLYCALADHQILEDMKQRGVEFVHVYCVDNILVRLADPVFIGFCVLQGADCGAKVVEKAYPEEPVGVVCQVDGVPQVVEYSEISPEIAGQLGADGGLLYNAGNICNHFFTRGFLDVVTREFEPLLRLHVAMKKVPYVDEEGNLVKPLRPNGIKMEKFVFDVFQFAKNFVAFEVCREEEFSPLKNDDTADRDNPSTCRRALLAQHYRWALQAGARFLDVHGVQLTEQSGMLPNGDPPAICEISPLVSYSGEGLEMYLQGRQLQSPFILDEDQARLLRPQDC", "length": 507 }, "evidence": [ { "id": "A0A3L7HDH6", "url": "https://omabrowser.org/oma/group/A0A3L7HDH6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "UDP-N-acetylglucosamine biosynthetic process", "id": "GO:0006048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006048", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HDH6", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HDH6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "UDP-N-acetylglucosamine diphosphorylase activity", "id": "GO:0003977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003977", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HDH6", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HDH6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { 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"sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7HDK2-1", "uniprot_ac": "A0A3L7HDK2", "uniprot_id": "A0A3L7HDK2_CRIGR", "mass": { "chemical_mass": 18330.0, "monoisotopic_mass": 18330.0 }, "refseq": { "ac": "XP_035302210", "name": "protein FAM163B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302210" }, "gene_names": [ { "name": "Fam163b", "type": "recommended", "evidence": [ { "id": "A0A3L7HDK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HDK2" } ] }, { "name": "Fam163b", "type": "synonym", "evidence": [ { "id": "XP_035302210", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302210" } ] } ], "protein_names": [ { "name": "Protein FAM163B", "type": "synonym", "evidence": [ { "id": "A0A3L7HDK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HDK2/entry#names_and_taxonomy" } ] }, { "name": "protein FAM163B", "type": "synonym", "evidence": [ { "id": "XP_035302210", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302210" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035302210", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302210" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HDK2", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HDK2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Fam163b", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HDK2", "locus": {} } ], "crossref": [ { "id": "100760830", "url": "https://www.ncbi.nlm.nih.gov/gene/100760830", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040280", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040280", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760830", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760830", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3L7HDK2", "url": "https://www.orthodb.org/?gene=A0A3L7HDK2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31396", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31396", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31396:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31396:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035302210", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302210", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HDK2", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HDK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HDK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HDK2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKDESEEDEEEPDFAVHSHLPPLHSNRNLVLTNGPALYPAATTSFSQKSPQARALCRSCSHYEPPTFFLQEPEDDDFEAVRNGGGRVAYKSISQEDVELPPATFGGLQALNPNRLSAMREAFSRSRSVSTDV", "length": 167, "header": "tr|A0A3L7HDK2-1|A0A3L7HDK2_CRIGR Isoform 1 of Protein FAM163B OS=Cricetulus griseus OX=10029 GN=Fam163b PE=3 SV=1 CANONICAL=A0A3L7HDK2-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HDK2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HDK2/entry#A0A3L7HDK2-1", "sequence": { "sequence": "MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKDESEEDEEEPDFAVHSHLPPLHSNRNLVLTNGPALYPAATTSFSQKSPQARALCRSCSHYEPPTFFLQEPEDDDFEAVRNGGGRVAYKSISQEDVELPPATFGGLQALNPNRLSAMREAFSRSRSVSTDV", "length": 167, "header": "tr|A0A3L7HDK2-1|A0A3L7HDK2_CRIGR Isoform 1 of Protein FAM163B OS=Cricetulus griseus OX=10029 GN=Fam163b PE=3 SV=1 CANONICAL=A0A3L7HDK2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HDK2", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HDK2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HDK2", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HDK2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760830", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760830", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HDK2", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HDK2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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This record is derived from a genomic sequence (NW_003613762.1) annotated using gene prediction method: Gnomon. 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Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614250.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003506560", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506560" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HF09", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HF09" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Muc15", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HF09", "locus": {} } ], "crossref": [ { "id": "100761085", "url": "https://www.ncbi.nlm.nih.gov/gene/100761085", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031371", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031371", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761085", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761085", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PDEWLTT", "url": "https://omabrowser.org/oma/group/PDEWLTT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7HF09", "url": "https://www.orthodb.org/?gene=A0A3L7HF09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45427", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45427", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45427:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45427:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15672", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15672", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003506560", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506560", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HF09", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HF09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HF09-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HF09-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLTFTKIAFISSLLILLPFGRPEKQNPGRKATEYTIEDLKTMGNKSIPLKRSTNLTLGNESSNISKPMLTNTSLLDLTRTYEPINSTSNWKAASSTMLPRPTSAYSAPPLAHHFVSKSPLNSSTADVNPLQVSEHSNPIHPTTSETFTWSLDNETMKTPDNISSTVSLLPLPPMTTPITPLTIEPTGWLATNNDDFAGFTPYQEKTTLQTTLKSTNNSKLFSDSSDPQKGNKNTGIIFGAILGGILGASLFSLVGYLLCGQRKTDSFSHRRLYDDRNEPVLRLDNAPEPYDVNFGNSSYYNSAVSDSSMPEGGESVHDGIPMDDIPPLRTSI", "length": 332, "header": "tr|A0A3L7HF09-1|A0A3L7HF09_CRIGR Isoform 1 of Mucin-15 OS=Cricetulus griseus OX=10029 GN=Muc15 PE=4 SV=1 CANONICAL=A0A3L7HF09-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HF09-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HF09/entry#A0A3L7HF09-1", "sequence": { "sequence": "MLTFTKIAFISSLLILLPFGRPEKQNPGRKATEYTIEDLKTMGNKSIPLKRSTNLTLGNESSNISKPMLTNTSLLDLTRTYEPINSTSNWKAASSTMLPRPTSAYSAPPLAHHFVSKSPLNSSTADVNPLQVSEHSNPIHPTTSETFTWSLDNETMKTPDNISSTVSLLPLPPMTTPITPLTIEPTGWLATNNDDFAGFTPYQEKTTLQTTLKSTNNSKLFSDSSDPQKGNKNTGIIFGAILGGILGASLFSLVGYLLCGQRKTDSFSHRRLYDDRNEPVLRLDNAPEPYDVNFGNSSYYNSAVSDSSMPEGGESVHDGIPMDDIPPLRTSI", "length": 332, "header": "tr|A0A3L7HF09-1|A0A3L7HF09_CRIGR Isoform 1 of Mucin-15 OS=Cricetulus griseus OX=10029 GN=Muc15 PE=4 SV=1 CANONICAL=A0A3L7HF09-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027279056", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279056" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HFA0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HFA0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "R3hdml", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HFA0", "locus": {} } ], "crossref": [ { "id": "cd18815", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18815", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100770937", "url": "https://www.ncbi.nlm.nih.gov/gene/100770937", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001283", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001283", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770937", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770937", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CNSNMCF", "url": "https://omabrowser.org/oma/group/CNSNMCF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7HFA0", "url": "https://www.orthodb.org/?gene=A0A3L7HFA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10334", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10334", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00188", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00188", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027279056", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027279056", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HFA0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HFA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HFA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HFA0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLLASIMGLAGLLLWTDHTVGALRMPNTTLVLGRPKNTAVWPLSGLGVPRYRQKRHISARDMSALLDYHNHIRASVHPPAANMEYMVWDEQLARSAEAWATQCIWAHGPSQLMKYVGQNLSIHSGRYRSVVDLVKSWSEEKRHYSFPTPKDCTPHCPWLCSGPVCSHYTQMVWASSSRLGCALHTCSSINVWGSTWQQAVYLVCNYAIKGNWIGEAPYKTGKPCSACPPSYQGNCNSNMCFSGLKSNRLPWI", "length": 253, "header": "tr|A0A3L7HFA0-1|A0A3L7HFA0_CRIGR Isoform 1 of Peptidase inhibitor R3HDML OS=Cricetulus griseus OX=10029 GN=R3hdml PE=3 SV=1 CANONICAL=A0A3L7HFA0-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HFA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HFA0/entry#A0A3L7HFA0-1", "sequence": { "sequence": "MPLLASIMGLAGLLLWTDHTVGALRMPNTTLVLGRPKNTAVWPLSGLGVPRYRQKRHISARDMSALLDYHNHIRASVHPPAANMEYMVWDEQLARSAEAWATQCIWAHGPSQLMKYVGQNLSIHSGRYRSVVDLVKSWSEEKRHYSFPTPKDCTPHCPWLCSGPVCSHYTQMVWASSSRLGCALHTCSSINVWGSTWQQAVYLVCNYAIKGNWIGEAPYKTGKPCSACPPSYQGNCNSNMCFSGLKSNRLPWI", "length": 253, "header": "tr|A0A3L7HFA0-1|A0A3L7HFA0_CRIGR Isoform 1 of Peptidase inhibitor R3HDML OS=Cricetulus griseus OX=10029 GN=R3hdml PE=3 SV=1 CANONICAL=A0A3L7HFA0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"MPLLYSIVGLAGLLLWMGHTVGALRMPNTTLVQGRPKNIAVWPLSGLGVPRHRRKRHISARDMNALLDYHNHIRASVHPPASNMEYMVWDEQLARAAEAWATQCIWAHGPSQLTKYVGQNLSVHSGRYRSVVDLVKSWSEEKRHYSFPAPKDCTPHCPWLCSGPVCSHYTQMVWASSSRLGCAIHTCSSINVWGSTWQQAVYLVCNYAIKGNWIGEAPYKTGKPCSACPPSYQGNCNSNMCFSGLKSNRLPWV", "length": 253 }, "evidence": [ { "id": "A0A3L7HFA0", "url": "https://omabrowser.org/oma/group/A0A3L7HFA0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9H3Y0-1", "protein_name": "Peptidase inhibitor R3HDML", "gene_name": "R3HDML", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLLPSTVGLAGLLFWAGQAVNALIMPNATPAPAQPESTAMRLLSGLEVPRYRRKRHISVRDMNALLDYHNHIRASVYPPAANMEYMVWDKRLARAAEAWATQCIWAHGPSQLMRYVGQNLSIHSGQYRSVVDLMKSWSEEKWHYLFPAPRDCNPHCPWRCDGPTCSHYTQMVWASSNRLGCAIHTCSSISVWGNTWHRAAYLVCNYAIKGNWIGESPYKMGKPCSSCPPSYQGSCNSNMCFKGLKSNKFTWF", "length": 253 }, "evidence": [ { "id": "A0A3L7HFA0", "url": "https://omabrowser.org/oma/group/A0A3L7HFA0/", "database": "OMA" } ], 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"authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7HHR9-1", "uniprot_ac": "A0A3L7HHR9", "uniprot_id": "A0A3L7HHR9_CRIGR", "mass": { "chemical_mass": 17769.0, "monoisotopic_mass": 17769.0 }, "refseq": { "ac": "XP_003506505", "name": "growth arrest and DNA damage-inducible protein GADD45 beta", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506505" }, "gene_names": [ { "name": "Gadd45b", "type": "recommended", "evidence": [ { "id": "A0A3L7HHR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HHR9" } ] }, { "name": "Gadd45b", "type": "synonym", "evidence": [ { "id": "XP_003506505", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506505" } ] } ], "protein_names": [ { "name": "Growth arrest and DNA damage-inducible protein GADD45 beta", "type": "synonym", "evidence": [ { "id": "A0A3L7HHR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HHR9/entry#names_and_taxonomy" } ] }, { "name": "growth arrest and DNA damage-inducible protein GADD45 beta", "type": "synonym", "evidence": [ { "id": "XP_003506505", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506505" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614244.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003506505", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506505" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HHR9", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HHR9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Gadd45b", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HHR9", "locus": {} } ], "crossref": [ { "id": "100766127", "url": "https://www.ncbi.nlm.nih.gov/gene/100766127", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004038", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004038", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024824", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024824", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029064", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029064", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766127", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766127", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RENDVRC", "url": "https://omabrowser.org/oma/group/RENDVRC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7HHR9", "url": "https://www.orthodb.org/?gene=A0A3L7HHR9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10411", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10411", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10411:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10411:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01248", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01248", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003506505", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506505", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HHR9", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HHR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HHR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HHR9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTLEELVASDNAAQKMQAVTAAVEQLLVAAQRQDRLTVGVYEAAKLMNVDPDSVVLCLLAIDEEEEDDIALQIHFTLIQSFCCDNDIDIVRVSGMQRLAQLLGEPAETLGTTEARDLHCLLVTNCHTDTWKSQGLVEVASYCEESRGNNQWVPYISLEER", "length": 160, "header": "tr|A0A3L7HHR9-1|A0A3L7HHR9_CRIGR Isoform 1 of Growth arrest and DNA damage-inducible protein GADD45 beta OS=Cricetulus griseus OX=10029 GN=Gadd45b PE=3 SV=1 CANONICAL=A0A3L7HHR9-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HHR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HHR9/entry#A0A3L7HHR9-1", "sequence": { "sequence": "MTLEELVASDNAAQKMQAVTAAVEQLLVAAQRQDRLTVGVYEAAKLMNVDPDSVVLCLLAIDEEEEDDIALQIHFTLIQSFCCDNDIDIVRVSGMQRLAQLLGEPAETLGTTEARDLHCLLVTNCHTDTWKSQGLVEVASYCEESRGNNQWVPYISLEER", "length": 160, "header": "tr|A0A3L7HHR9-1|A0A3L7HHR9_CRIGR Isoform 1 of Growth arrest and DNA damage-inducible protein GADD45 beta OS=Cricetulus griseus OX=10029 GN=Gadd45b PE=3 SV=1 CANONICAL=A0A3L7HHR9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614244.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003506503", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506503" } ] }, { "annotation": "Displays low GTPase activity and exists predominantly in the GTP-bound form.", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HHU8", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HHU8#function" }, { "database": "UniProtKB", "id": "ARBA00055536", "url": "https://www.uniprot.org/uniprotkb/ARBA00055536#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HHU8", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HHU8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Diras1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HHU8", "locus": {} } ], "crossref": [ { "id": "100765547", "url": "https://www.ncbi.nlm.nih.gov/gene/100765547", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765547", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765547", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LGPIYQL", "url": "https://omabrowser.org/oma/group/LGPIYQL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7HHU8", "url": "https://www.orthodb.org/?gene=A0A3L7HHU8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24070", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24070", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003506503", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506503", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HHU8", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HHU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HHU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HHU8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPEQSNDYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDTTGSHQFPAMQRLSISKGHAFILVFSVTSKQSLDELSPIYKLIVQIKGSVEDIPIMLVGNKCDETQREVHTREAQAVAQEWKCAFMETSAKMNYNVKELFQELLTLETRRSVSLSVDGKRSSKQKRADRIKGKCALM", "length": 198, "header": "tr|A0A3L7HHU8-1|A0A3L7HHU8_CRIGR Isoform 1 of GTP-binding protein Di-Ras1 OS=Cricetulus griseus OX=10029 GN=Diras1 PE=3 SV=1 CANONICAL=A0A3L7HHU8-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HHU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HHU8/entry#A0A3L7HHU8-1", "sequence": { "sequence": "MPEQSNDYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDTTGSHQFPAMQRLSISKGHAFILVFSVTSKQSLDELSPIYKLIVQIKGSVEDIPIMLVGNKCDETQREVHTREAQAVAQEWKCAFMETSAKMNYNVKELFQELLTLETRRSVSLSVDGKRSSKQKRADRIKGKCALM", "length": 198, "header": "tr|A0A3L7HHU8-1|A0A3L7HHU8_CRIGR Isoform 1 of GTP-binding protein Di-Ras1 OS=Cricetulus griseus OX=10029 GN=Diras1 PE=3 SV=1 CANONICAL=A0A3L7HHU8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HHU8", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HHU8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HHU8", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HHU8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765547", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765547", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2R9W2-1", "protein_name": "DIRAS family GTPase 1", "gene_name": "DIRAS1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPEQSNDYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDTTGSHQFPAMQRLSISKGHAFILVFSVTSKQSLEELGPIYKLIVQIKGSVEDIPVMLVGNKCDETQREVDTREAQAVAQEWKCAFMETSAKMNYNVKELFQELLTLETRRNMSLNIDGKRSSKQKRTDRIKGKCVLM", "length": 198 }, "evidence": [ { "id": "A0A3L7HHU8", "url": "https://omabrowser.org/oma/group/A0A3L7HHU8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AAA9RW90-1", "protein_name": "DIRAS family GTPase 1", "gene_name": "DIRAS1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPEQSNDYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDTTGSHQFPAMQRLSISKGHAFILVFSVTSKQSLEELGPIYKLIVQIKGSVEDIPVMLVGNKCDETQREVDTREAQAVAQEWKCAFMETSAKMNYNVKELFQELLTLETRRNMSLNIDGKRSSKQKRTDRIKGKCILM", "length": 198 }, "evidence": [ { "id": "A0A3L7HHU8", "url": "https://omabrowser.org/oma/group/A0A3L7HHU8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D4A304-1", "protein_name": "DIRAS family GTPase 1", "gene_name": "Diras1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEQSNDYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDTTGSHQFPAMQRLSISKGHAFILVFSVTSKQSLDELSPIYKLIVQIKGSVEDIPIMLVGNKCDETQREVHTREAQAVAQEWKCAFMETSAKMNYNVKELFQELLTLETRRSVSLSVDGKRSNKQKRADRIKGKCALM", "length": 198 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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This record is derived from a genomic sequence (NW_003613838.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_003613889.1) and transcript sequence (IACG01087578.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003502330.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003502330", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502330" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HK70", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK70" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tiprl", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK70", "locus": {} } ], "crossref": [ { "id": "100766692", "url": "https://www.ncbi.nlm.nih.gov/gene/100766692", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007303", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007303", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766692", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766692", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3L7HK70", "url": "https://www.orthodb.org/?gene=A0A3L7HK70", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21021", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21021", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21021:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21021:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04176", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04176", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003502330", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502330", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HK70", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HK70-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK70-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMLHGFQSSHQDFSFGPWKLTAAKTHIMKSADVEKLADELHMPSLPEMMFGDNVLRIQHGSGFGIEFNATDALRCVNNYQGMLKVACAEEWQESRTEGEHSKEVLKPYDWTYTTDYKGTLLGESLKLKVVPTTDHIDTEKLKAREQIKFFEEVLLFEDELHDHGVSSLSVKIRVMPSSFFLLLRFFLRIDGVLIRMNDTRLYHEADKTYMLREYTSRESKIANLMHVPPSLFTEPNEISQYLPIKEAVCEKLVFPERVDSSPADSQSTPSE", "length": 271, "header": "tr|A0A3L7HK70-1|A0A3L7HK70_CRIGR Isoform 1 of TIP41-like protein OS=Cricetulus griseus OX=10029 GN=Tiprl PE=3 SV=1 CANONICAL=A0A3L7HK70-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HK70-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HK70/entry#A0A3L7HK70-1", "sequence": { "sequence": "MMLHGFQSSHQDFSFGPWKLTAAKTHIMKSADVEKLADELHMPSLPEMMFGDNVLRIQHGSGFGIEFNATDALRCVNNYQGMLKVACAEEWQESRTEGEHSKEVLKPYDWTYTTDYKGTLLGESLKLKVVPTTDHIDTEKLKAREQIKFFEEVLLFEDELHDHGVSSLSVKIRVMPSSFFLLLRFFLRIDGVLIRMNDTRLYHEADKTYMLREYTSRESKIANLMHVPPSLFTEPNEISQYLPIKEAVCEKLVFPERVDSSPADSQSTPSE", "length": 271, "header": "tr|A0A3L7HK70-1|A0A3L7HK70_CRIGR Isoform 1 of TIP41-like protein OS=Cricetulus griseus OX=10029 GN=Tiprl PE=3 SV=1 CANONICAL=A0A3L7HK70-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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}, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7HL20-1", "uniprot_ac": "A0A3L7HL20", "uniprot_id": "A0A3L7HL20_CRIGR", "mass": { "chemical_mass": 35036.0, "monoisotopic_mass": 35036.0 }, "refseq": { "ac": "XP_007645725", "name": "olfactory receptor 10H1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645725" }, "gene_names": [ { "name": "LOC100773239", "type": "recommended", "evidence": [ { "id": "A0A3L7HL20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HL20" } ] }, { "name": "LOC100773239", "type": "synonym", "evidence": [ { "id": "XP_007645725", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645725" } ] } ], "protein_names": [ { "name": "Olfactory receptor 10H1", "type": "synonym", "evidence": [ { "id": "A0A3L7HL20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HL20/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 10H1", "type": "synonym", "evidence": [ { "id": "XP_007645725", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645725" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614316.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007645725", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645725" } ] }, { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HL20", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HL20#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HL20", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HL20" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100773239", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HL20", "locus": {} } ], "crossref": [ { "id": "cd15225", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15225", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100773239", "url": "https://www.ncbi.nlm.nih.gov/gene/100773239", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773239", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773239", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MPGENCT", "url": "https://omabrowser.org/oma/group/MPGENCT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7HL20", "url": "https://www.orthodb.org/?gene=A0A3L7HL20", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007645725", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007645725", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HL20", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HL20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HL20-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HL20-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQGINHSGVSEFILIGFSTFPHLQMVFFLLFLLMYLFTLLGNLFIMATIWSERSLHTPMYLFLCALSISEIFYTFAIIPRMLADLLSTLHSIAFLACASQMFFSFTFGFTHSFLLTVMGYDRYVAICHPLRYNVLMSPRGCTCLVAWSWVGGSFMGTVVTTAIFNLTFCGPNEIHHFACHVPPLLKLACGENVLVVARGVGLVCITALLGCFLLILLSYAFIVAAILKIPSAEGRHKAFSTCASHLTVVIVHYGFASVIYLKPKGPKSLEGDTLMGITYTVLTPFLSPIIFSLRNKELKNAMKKAFLSKLYPEII", "length": 315, "header": "tr|A0A3L7HL20-1|A0A3L7HL20_CRIGR Isoform 1 of Olfactory receptor 10H1 OS=Cricetulus griseus OX=10029 GN=LOC100773239 PE=3 SV=1 CANONICAL=A0A3L7HL20-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HL20-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HL20/entry#A0A3L7HL20-1", "sequence": { "sequence": "MQGINHSGVSEFILIGFSTFPHLQMVFFLLFLLMYLFTLLGNLFIMATIWSERSLHTPMYLFLCALSISEIFYTFAIIPRMLADLLSTLHSIAFLACASQMFFSFTFGFTHSFLLTVMGYDRYVAICHPLRYNVLMSPRGCTCLVAWSWVGGSFMGTVVTTAIFNLTFCGPNEIHHFACHVPPLLKLACGENVLVVARGVGLVCITALLGCFLLILLSYAFIVAAILKIPSAEGRHKAFSTCASHLTVVIVHYGFASVIYLKPKGPKSLEGDTLMGITYTVLTPFLSPIIFSLRNKELKNAMKKAFLSKLYPEII", "length": 315, "header": "tr|A0A3L7HL20-1|A0A3L7HL20_CRIGR Isoform 1 of Olfactory receptor 10H1 OS=Cricetulus griseus OX=10029 GN=LOC100773239 PE=3 SV=1 CANONICAL=A0A3L7HL20-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HL20", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HL20" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HL20", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HL20" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773239", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773239", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SA00-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100524975", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQGANLSAVTEFILIGFSTFPHLQLTFFLLFLLMYLFTLLGNLLIMATIWRERSLHTPMYLFLCALSISEILYTFAIIPRMLADLLSTHHSIAFSACASQMFFSFTFGFTHSFLLTVMGYDRYVAICHPLRYNVLMSPGGCACLVVWSWAGGLVMGLVVTSAIFHLTFCGPNEIHHFACHVPPLLKLACGTDVHVVAKGVGLVCLSALLGCCLLILLSYAFIVAAILRIPSAEGRHKAFSTCVSHLTVVVVHYGFASVIYLKPKGPPSLEGDTLMGITYTVLTPFLSPIIFSLRNKELKNTMNKTFSKLYPETM", "length": 314 }, "evidence": [ { "id": "A0A3L7HL20", "url": "https://omabrowser.org/oma/group/A0A3L7HL20/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q0MQ71-1", "protein_name": "Olfactory receptor family 10 subfamily H member 1", "gene_name": "OR10H1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQGANFSAVTEFILIGFSTFPHLQLMFFLLFLLMYLFTLLGNLLIMATIWREHSLHTPMYLFLCALSISEILYTFAIIPRMLADLLSTDRSISFTACASQMFFSFMFGFTHSFLLTVMGYDRYVAICHPLRYNVLMSPRGCACLVAWSWAGGSVMGLVVTSAIFHLIFCGPNEVHHFACHVPPLLKLACGTEVQVVAKGVGLVCITALLGCGLLILLSYAFIVAAILRIPSAEGRHKAFSTCASHLTVVVVHYGFASVIYLKPKGPQSLEGDTLMGITYTVLTPFLSPIIFSLRNKELKIAMKKTFLSKLYPEKI", "length": 315 }, "evidence": [ { "id": "A0A3L7HL20", "url": "https://omabrowser.org/oma/group/A0A3L7HL20/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9Y4A9-1", "protein_name": "Olfactory receptor 10H1", "gene_name": "OR10H1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQRANHSTVTQFILVGFSVFPHLQLMLFLLFLLMYLFTLLGNLLIMATVWSERSLHTPMYLFLCALSVSEILYTVAIIPRMLADLLSTQRSIAFLACASQMFFSFSFGFTHSFLLTVMGYDRYVAICHPLRYNVLMSPRGCACLVGCSWAGGLVMGMVVTSAIFHLAFCGHKEIHHFACHVPPLLKLACGDDVLVVAKGVGLVCITALLGCFLLILLSYAFIVAAILKIPSAEGRNKAFSTCASHLTVVVVHYGFASVIYLKPKSPQSLEGDTLMGITYTVLTPFLSPIIFSLRNKELKVAMKKTFFSKLYPEKNVMM", "length": 318 }, "evidence": [ { "id": "A0A3L7HL20", "url": "https://omabrowser.org/oma/group/A0A3L7HL20/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HL20", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HL20" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HL20", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HL20" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HL20", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HL20" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3L7HL20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HL20" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 41, "end_pos": 291, "start_aa": "Gly", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 165, "end_pos": 167 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7HLC8-1", "uniprot_ac": "A0A3L7HLC8", "uniprot_id": "A0A3L7HLC8_CRIGR", "mass": { "chemical_mass": 6956.0, "monoisotopic_mass": 6956.0 }, "refseq": { "ac": "XP_003498784", "name": "ATP synthase subunit ATP5MPL, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498784" }, "gene_names": [ { "name": "Atp5mpl", "type": "recommended", "evidence": [ { "id": "A0A3L7HLC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HLC8" } ] }, { "name": "Atp5mpl", "type": "synonym", "evidence": [ { "id": "XP_003498784", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498784" } ] } ], "protein_names": [ { "name": "ATP synthase subunit ATP5MPL, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_003498784", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498784" }, { "id": "A0A3L7HLC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HLC8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 129 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613702.1) and transcript sequence (IACG01067361.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003498784.1. 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. 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"protein_names": [ { "name": "Protein FAM243A", "type": "synonym", "evidence": [ { "id": "A0A3L7HMU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMU7/entry#names_and_taxonomy" } ] }, { "name": "protein FAM243A", "type": "synonym", "evidence": [ { "id": "XP_003495609", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495609" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003495609", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495609" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HMU7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMU7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Fam243a", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMU7", "locus": {} } ], "crossref": [ { "id": "100760147", "url": "https://www.ncbi.nlm.nih.gov/gene/100760147", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR037728", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037728", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760147", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760147", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CIVHAGG", "url": "https://omabrowser.org/oma/group/CIVHAGG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7HMU7", "url": "https://www.orthodb.org/?gene=A0A3L7HMU7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35969", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35969", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35969:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35969:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27940", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27940", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003495609", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495609", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HMU7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HMU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMU7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARLTNSLLKSIVIRTQFDSVRRKQCLQYLNTLRTLQYDGYKTVYFGETEIPETLVTGEDFSDSYYMHSPTWCILHAGGSQGWVPWKYRMFLRDDLCIKQEDSLFFEFCDVIKKAYGKCAIVVKGQRQQDETKPKADMEGEAQAYVPTSINLTSIVCSPGVAKSYGHELISLPSLYNYLNPLDSAWSSMKWFIINNRKEFCLQSADDVYTYQYILFSDLISKGIEKVSLSKWKALTNKVRRWENYYLGKFS", "length": 251, "header": "tr|A0A3L7HMU7-1|A0A3L7HMU7_CRIGR Isoform 1 of Protein FAM243A OS=Cricetulus griseus OX=10029 GN=Fam243a PE=4 SV=1 CANONICAL=A0A3L7HMU7-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HMU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HMU7/entry#A0A3L7HMU7-1", "sequence": { "sequence": "MARLTNSLLKSIVIRTQFDSVRRKQCLQYLNTLRTLQYDGYKTVYFGETEIPETLVTGEDFSDSYYMHSPTWCILHAGGSQGWVPWKYRMFLRDDLCIKQEDSLFFEFCDVIKKAYGKCAIVVKGQRQQDETKPKADMEGEAQAYVPTSINLTSIVCSPGVAKSYGHELISLPSLYNYLNPLDSAWSSMKWFIINNRKEFCLQSADDVYTYQYILFSDLISKGIEKVSLSKWKALTNKVRRWENYYLGKFS", "length": 251, "header": "tr|A0A3L7HMU7-1|A0A3L7HMU7_CRIGR Isoform 1 of Protein FAM243A OS=Cricetulus griseus OX=10029 GN=Fam243a PE=4 SV=1 CANONICAL=A0A3L7HMU7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NW_003613861.1) and transcript sequence (IACG01058577.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007640623.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007640623", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640623" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HN76", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HN76" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mllt1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HN76", "locus": {} } ], "crossref": [ { "id": "cd16906", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16906", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100773703", "url": "https://www.ncbi.nlm.nih.gov/gene/100773703", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR038704", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038704", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052790", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052790", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773703", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773703", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3L7HN76", "url": "https://www.orthodb.org/?gene=A0A3L7HN76", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47827", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47827", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47827:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47827:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03366", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03366", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17793", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17793", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007640623", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640623", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HN76", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HN76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HN76-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HN76-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZI2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQH5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQH5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDNQCTVQVKLELGHRAQLRKKPTTEGFTHDWMVFVRGPEQCDIQHFVEKVIFRLHDSFPKPKRVCKEPPYKVEESGYAGFIMLIEVYFKNKEEPRKVCFTYDLFLNLEGNPPVNHLRCEKLTFNNPTTEFRCKLLMAGGVMVMPEGADTVSRPSPDYPMLPTIPLSAFSDPKKNKPSHGSKDANKESGKASKPHKVAREHRERPRKDSESRSCSKEPEREPKSAKDAVRKLPKEEKAPAPKAAFKEPKMALKETKLESLSPKGAPQPPTLPKASSKRPAATDSPKPSAKKPKKSGSKGTRRAPGTSPRTSSSFPDKKVARDKSSSKGDKGKADSESREAKRTQQAEDSNSEDEASFRSESAQSSPANASSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQSEESDEDDSSSGEEATIKANPGRESRLSFSDSESDNSADSCLPGREPPPPQKPLPPSSKVSGRRSPEPCSKPEKILKKATYDKAYTDELVELHRRLMALRERNVLQQIVNLIEETGHFNVTNTTFDFDLFSLDESTVRKLQSCLEAVAT", "length": 549, "header": "tr|A0A3L7HN76-1|A0A3L7HN76_CRIGR Isoform 1 of Protein ENL isoform X4 OS=Cricetulus griseus OX=10029 GN=Mllt1 PE=4 SV=1 CANONICAL=A0A3L7HN76-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HN76-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HN76/entry#A0A3L7HN76-1", "sequence": { "sequence": "MDNQCTVQVKLELGHRAQLRKKPTTEGFTHDWMVFVRGPEQCDIQHFVEKVIFRLHDSFPKPKRVCKEPPYKVEESGYAGFIMLIEVYFKNKEEPRKVCFTYDLFLNLEGNPPVNHLRCEKLTFNNPTTEFRCKLLMAGGVMVMPEGADTVSRPSPDYPMLPTIPLSAFSDPKKNKPSHGSKDANKESGKASKPHKVAREHRERPRKDSESRSCSKEPEREPKSAKDAVRKLPKEEKAPAPKAAFKEPKMALKETKLESLSPKGAPQPPTLPKASSKRPAATDSPKPSAKKPKKSGSKGTRRAPGTSPRTSSSFPDKKVARDKSSSKGDKGKADSESREAKRTQQAEDSNSEDEASFRSESAQSSPANASSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQSEESDEDDSSSGEEATIKANPGRESRLSFSDSESDNSADSCLPGREPPPPQKPLPPSSKVSGRRSPEPCSKPEKILKKATYDKAYTDELVELHRRLMALRERNVLQQIVNLIEETGHFNVTNTTFDFDLFSLDESTVRKLQSCLEAVAT", "length": 549, "header": "tr|A0A3L7HN76-1|A0A3L7HN76_CRIGR Isoform 1 of Protein ENL isoform X4 OS=Cricetulus griseus OX=10029 GN=Mllt1 PE=4 SV=1 CANONICAL=A0A3L7HN76-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GZI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HN76/entry#A0A9J7GZI2-1", "sequence": { "sequence": "MTGWSSCVGLSSVTSSTSWRRSSSDCMTASPNPSVEEPRKVCFTYDLFLNLEGNPPVNHLRCEKLTFNNPTTEFRCKLLMAGGVMVMPEGADTVSRPSPDYPMLPTIPLSAFSDPKKNKPSHGSKDANKESGKASKPHKVAREHRERPRKDSESRSCSKEPEREPKSAKDAVRKLPKEEKAPAPKAAFKEPKMALKETKLESLSPKGAPQPPTLPKASSKRPAATDSPKPSAKKPKKSGSKGTRRAPGTSPRTSSSFPDKKVARDKSSSKGDKGKADSESREAKRTQQAEDSNSEDEASFRSESAQSSPANASSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQSEESDEDDSSSGEEATIKANPGRESRLSFSDSESDNSADSCLPGREPPPPQKPLPPSSKVSGRRSPEPCSKPEKILKKATYDKAYTDELVELHRRLMALRERNVLQQIVNLIEETGHFNVTNTTFDFDLFSLDESTVRKLQSCLEAVAT", "length": 492, "header": "tr|A0A9J7GZI2-1|A0A9J7GZI2_CRIGR Computationally mapped isoform of Protein ENL isoform X3 OS=Cricetulus griseus OX=10029 GN=Mllt1 PE=4 SV=1 CANONICAL=A0A3L7HN76-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JQH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HN76/entry#A0A9J7JQH5-1", "sequence": { "sequence": "MDNQCTVQVKLELGHRAQLRKKPTTEGFTHDWMVFVRGPEQCDIQHFVEKVIFRLHDSFPKPKRVCKEPPYKVEESGYAGFIMLIEVYFKNKEEPRKVCFTYDLFLNLEGNPPVNHLRCEKLTFNNPTTEFRCKLLMAGGVMVMPEGADTVSRPSPDYPMLPTIPLSAFSDPKKNKPSHGSKDANKESGKASKPHKVAREHRERPRKDSESRSCSKEPEREPKSAKDAVRKLPKEEKAPAPKAAFKEPKMALKETKLESLSPKGAPQPPTLPKASSKRPAATDSPKPSAKKPKKSGSKGTRRAPGTSPRTSSSFPDKKVARDKSSSKGDKGKADSESREAKRTQQAEDSNSEDEASFRSESAQSSPANASSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQSEESDEDDSSSGEEATIKANPGRESRLSFSDSESDNSADSCLPGREPPPPQKPLPPSSKVSGRRSPEPCSKPEKILKKATYDKAYTDELVELHRRLMALRERNVLQQTGHFNVTNTTFDFDLFSLDESTVRKLQSCLEAVAT", "length": 542, "header": "tr|A0A9J7JQH5-1|A0A9J7JQH5_CRIGR Computationally mapped isoform of Protein ENL isoform X2 OS=Cricetulus griseus OX=10029 GN=Mllt1 PE=4 SV=1 CANONICAL=A0A3L7HN76-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HN76", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HN76" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HN76", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HN76" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773703", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773703", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HN76", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HN76" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HN76", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HN76" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HN76", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HN76" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "transcription elongation factor complex", "id": "GO:0008023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008023", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HN76", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HN76" } ], "pmid": "" }, { "name": "fibrillar center", "id": "GO:0001650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001650", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HN76", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HN76" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 386, "end_pos": 388, "annotation": "n_glycosylation_sequon" }, { "start_pos": 519, "end_pos": 521, "annotation": "n_glycosylation_sequon" }, { "start_pos": 522, "end_pos": 524, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3L7HN76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HN76" }, { "id": "PS51037", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51037" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "YEATS", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 138, "start_aa": "Met", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 368, "end_pos": 370 }, { "start_pos": 386, "end_pos": 388 }, { "start_pos": 519, "end_pos": 521 }, { "start_pos": 522, "end_pos": 524 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7HNH9-1", "uniprot_ac": "A0A3L7HNH9", "uniprot_id": "A0A3L7HNH9_CRIGR", "mass": { "chemical_mass": 22080.0, "monoisotopic_mass": 22080.0 }, "refseq": { "ac": "XP_035300744", "name": "ras-related protein Rap-2c-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300744" }, "gene_names": [ { "name": "LOC113835835", "type": "recommended", "evidence": [ { "id": "A0A3L7HNH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HNH9" } ] }, { "name": "LOC113835835", "type": "synonym", "evidence": [ { "id": "XP_035300744", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300744" } ] } ], "protein_names": [ { "name": "Ras-related protein Rap-2c-like", "type": "synonym", "evidence": [ { "id": "A0A3L7HNH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HNH9/entry#names_and_taxonomy" } ] }, { "name": "ras-related protein Rap-2c-like", "type": "synonym", "evidence": [ { "id": "XP_035300744", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300744" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. 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Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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"annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613657.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003497681", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497681" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HNV2", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HNV2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Aste1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HNV2", "locus": {} } ], "crossref": [ { "id": "100765786", "url": "https://www.ncbi.nlm.nih.gov/gene/100765786", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006085", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006085", "database": "InterPro", "categories": [ "Protein Classification" ] 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"categories": [ "Protein Classification" ] }, { "id": "PTHR15665:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15665:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00752", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00752", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27698", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27698", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003497681", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497681", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HNV2", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HNV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HNV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HNV2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQJ5", "url": 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676, "header": "tr|A0A3L7HNV2-1|A0A3L7HNV2_CRIGR Isoform 1 of Protein asteroid homolog 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Aste1 PE=3 SV=1 CANONICAL=A0A3L7HNV2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JQJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HNV2/entry#A0A9J7JQJ5-1", "sequence": { "sequence": "MAILFSTDFASIQTWNSDGGCDISDKKLTTLKDRAREKIQAAHSLSVGGGGNVCPLLIREVFIQVLIRLKVCFVQSFSEADRDIMTLANHWNCPVLSSDSDFCIFDLKSGFCPLNSFQWRNLNTVKNTQDYYIPAKCFSLAAFCHYFNNMNKSLLPLFAVLCGNDHVNLSIIETILSKARLPLSSKGRRYHRVQGLLNWLSHFDNPAEALDNVLKYLPKKGREDVKELLYCSMEEYQPSQVKLQDFFLYGTYVCPDALNLGLPEWVLVALAKGQLPPFISDALVLQRTFLHTQVENMQRPNAHRIAQPIRQIIYGLLLNSPSLPESTRNAVPSQRLAFNEVERISKNIKTSVVYAKQLLKDHSDLSKLTELPLARRQILLLEALKVNQVVLESIPALLKLPIAVTCYWLQSTEAKAKLHHLQALLLGMLMEPLHAIINCSGEEDLQAGGAKMLYEELQRAKAPMRPVARLDLDTAHVFCQWQCCLQMGLYLNQLLSNPLPEPDLTQLYSGSLVHGLCQQLLTSTSAESLLNMCPRAKQFYEHLFNATRSYAPAELFLLKAQSNSKKRRQKKKVASQSKNKVVTTSDTRHWYDRNNRFGLLMVESLEDHEETSELE", "length": 615, "header": "tr|A0A9J7JQJ5-1|A0A9J7JQJ5_CRIGR Computationally mapped isoform of Protein asteroid homolog 1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Aste1 PE=3 SV=1 CANONICAL=A0A3L7HNV2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HNV2", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HNV2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HNV2", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HNV2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765786", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765786", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K873-1", "protein_name": "Asteroid homolog 1", "gene_name": "Aste1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGIRGLMSFVEDYSNEFFVDLKLRDTKIIIDGYSLFHRLCFNSNLELRYGGDYDSFADVVQKFFESLFACHICPYVVLDGGCDITDKKLTTLKDRAREKIQAAHSLSVGGGGNVCPLLIREVFIQVLIRLKVCFVQSFSEADRDIMTLANHWNCPVLSSDSDFCIFDLKSGFCPLNSFQWRNLDTIKDTQDYYIPAKSFSLDAFCHYFNNMNKALLPLFAVLCGNDHVNLPIMETFISKVRLPFSSKGRRYHRVLGLLNWLSNFDDPTEALDNVLKSLPKKSRETVRELLCCSMEEYQQSQVKLQDFFQYGTYVCTDALNLGLPGWVLAALAKAQLPPFISDALVLRRTFLHTQVENMQRPNAHRVSQPIRQIIYGLLLNAPSHPEDKSPNTLPSQLLAFNEVERIKTNIKTSTVYVKQLLKDHCDLSKLAELPLSRRQMLLLEALKVKQVVLESIPTSLKLPIAVTCYWLQSTEAKAKLHHLQALLLGMLREPLHVIINSPDSEDPRRGGAKMLYEELQQVKAAMRPGPRLDLDTAHVFCQWQSCLQMGLYLNQLLSTPLPEPNLTWLYNGNLVHRLCQQLLASCSAESLLSICPEARQLYEHLFSATRSYAPAELFLPKATSKSKKRRQKKKIASLGTTSDTKHCSYAIK", "length": 652 }, "evidence": [ { "id": "A0A3L7HNV2", "url": "https://omabrowser.org/oma/group/A0A3L7HNV2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A3Q1LUG8-1", "protein_name": "Asteroid homolog 1", "gene_name": "ASTE1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MIMGIRGLMSFVEDHSNEFFTDVKLRDTKIIIDGYALFHRLYFSSNLELRYGGDYDSFTDVVQKFFESLFACKICPYVVLDGGCDISDKKLNTLKDRAREKIQMAHSLSVGGGGYVCPLLIREVFIQVLTKLQVCFVQCFSEADRDIMTLANHWNCPVLSSDSDFCIFDLKSGFCPLNGFQWRNVNTIKGTRDRYIPAKCFFLDALCCHFGIMNKTLLPLFAVLCGNDHVNLPVMETFLSKVRFPLGAANSKGRRHHRVLGLLNWLSRFADPTEALDSVLNHLPKKRRGTVKELLCRSMEEYVQAQGRLQDFFQHGAYTCPDTWNPGLPPWVLAALARGQLSPFISDALVLRRTILHTQVENMQRPNAHRISLPIRQVIYGLLVNALPHVRNVAWDALPPQPPTFSEVERINKNIKTSIVNAVELPKDHSDLSKLTELSLASRQMLLLETLKVKQSLLDPVPAALKLPVAVSCYWVQHAEATLKLHHLQALLLGMLLGPLRAMASSPEEKAGRGGGAETLYAELQRVKAPPGTRLDLDTAHVFCQWQCCLQMGLYLNQLLSTPLPEPDLTRLYSGSLVHGLCRQLLTSASVESLLRLCPEAQQLYEHLFSATRSCAPAELFLPKGKLNSKRRKQKKSGISWSENRVGTTLNARSWHEGSNPFELLMVETLENEEAPELK", "length": 679 }, "evidence": [ { "id": "A0A3L7HNV2", "url": "https://omabrowser.org/oma/group/A0A3L7HNV2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8V0Z097-1", "protein_name": "Asteroid homolog 1", "gene_name": "ASTE1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGVPGLTGFVEECGAFFAELRVRDTKLVIDGSSLYYHLFFASAADFRRGGDYGPFAAAVDEFFAVLRSCGVAAFVVLDGGRGAADRKLGTLRERAAERLCRAHGLSRGEGGRVLPLLARHAFVQALRRAAVPFVQCWAEADREVAALANRWGCPVLSLDSDFFIFELAGGYCPLSAFRWRDVRAERSGRYIPARRFQAESFCGRFGQLRRSVLPLFAVMSGNDYVDVTEFEGFLGKVRLPGRHGRARGLLGWLAGFAGPEEAADAVLKRLGGRRRDAVRELLRAALEDYAPSHVNLEEFFLEGRYRCEEAEASGLPSWLLGALARGELAPLVANVVTLRSTFLHVQVEDMRRPSAHCAALPIRRVLYGLLLRAATRADAQPQSQSGALPAVCEFDRVQKSVKKTFVQAASLPAPFGEDGFSLAKLVEVPVSHRQLLLLETLGVKMSLLESVPAHLQLPVAVTCYWTRCSEPKVNLHHLKALLLMIVSGELHRITDDPELTVLHPEDNSIAYNEFLKWKEEKLQNKDFDLDAAHGFCQWQCCLEMGLYLNQLLCSPLAEPDLARLYSGTVVHGLYRDLKSTPSVENVFSSSPKLTELYQVLLNVVMSAVSPDFFQKKTEVKSESRKKKKASKKTKAVRCAVSETQYLCDVNRFASLSMDD", "length": 659 }, "evidence": [ { "id": "A0A3L7HNV2", "url": "https://omabrowser.org/oma/group/A0A3L7HNV2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q1LYL8-1", "protein_name": "Single-strand DNA endonuclease ASTE1", "gene_name": "aste1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGVQGLKTYIESSSRNDLKTWAFRDKQLIIDGCNLFYSLCFDSNLDQIHGGDYDTFEKVVRQFFENLSACDVHPYVVIDGGDDHTDKKWDTLLTRKQKKIKDAYDLSVGKRRQVLPLLTEKVFKQVLKKLKVPVVQTLEEADWEIAALAEEWNCPVLSNDSDFYIFNLRAGLLPITHFHWRKVRVNRKTNQKFILSKHFIARKFCKSFKMNVSLLPVFASILGNDYVKLPNIKNRHWERYSNPGSENPQIEGLLNWLSQFSGPDEAISALLRPTSNKTKAQEELSHGIQDYKLVPGSLAQIFRSTKVPQKISKGPLHVLPRWTLRPILDGKMSSYIINVLLHNRASLNAQVEDFQLPSANETSLHIRQVFYGLLLLGEQQTAGKRESVKGTTKRYVVEYSRQQIKRSSENVEAIQTKAMEGLRLETLYQEPHAVRLQVILDTLGVSCEMLKGTPDALQLQMFVTRYWLVNAEPQPCRVHLWGLLLGMVYGKLSSSPNAQKDMLSRLRVKASRKGGSVDIDVAHAYSQWQSCLKYSLNLNYLLSFPLTEPDCASLYRGSLVHQAVGELRRGISLEALLVKGSSAERIFKQLKDIIVSLMGDDFIKKMKSGLEHRDAGKTQRASKGQKDELDIYFEQMMIESIDSEDEELLDVRKSKAKNHLMELPVCPIRARHKAKARNARHPCKKYERRCFE", "length": 692 }, "evidence": [ { "id": "A0A3L7HNV2", "url": "https://omabrowser.org/oma/group/A0A3L7HNV2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2TB18-1", "protein_name": "Single-strand DNA endonuclease ASTE1", "gene_name": "ASTE1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGIRGLMSFVEDHSNEFFTDLKLRDTKIVIDGYALFHRLCFSSNLDLRYGGDYDSFADVVQKFFESLFACNICPYVVLDGGCDISDKKLTTLKDRAREKIQMAHSLSVGGSGYVCPLLIREVFIQVLIKLRVCFVQCFSEADRDIMTLANHWNCPVLSSDSDFCIFDLKTGFCPLNSFQWRNMNTIKGTQNYIPAKCFSLDAFCHHFSNMNKALLPLFAVLCGNDHVNLPIMETFLSKARLPLGATSSKGRRHHRILGLLNWLSHFANPTEALDNVLKYLPKKDRENVKELLCCSMEEYQQSQVKLQDFFQCGTYVCPDALNLGLPEWVLVALAKGQLSPFISDALVLRRTILPTQVENMQQPNAHRISQPIRQIIYGLLLNASPHLDKTSWNALPPQPLAFSEVERINKNIRTSIIDAVELAKDHSDLSRLTELSLRRRQMLLLETLKVKQTILEPIPTSLKLPIAVSCYWLQHTETKAKLHHLQSLLLTMLVGPLIAIINSPGKEELQEDGAKMLYAEFQRVKAQTRLGTRLDLDTAHIFCQWQSCLQMGMYLNQLLSTPLPEPDLTRLYSGSLVHGLCQQLLASTSVESLLSICPEAKQLYEYLFNATRSYAPAEIFLPKGRSNSKKKRQKKQNTSCSKNRGRTTAHTKCWYEGNNRFGLLMVENLEEHSEASNIE", "length": 679 }, "evidence": [ { "id": "A0A3L7HNV2", "url": "https://omabrowser.org/oma/group/A0A3L7HNV2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BIR2-1", "protein_name": "Single-strand DNA endonuclease ASTE1", "gene_name": "Aste1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGIRGLMSFVEDYSNEFFVDLKLRNTKLIIDGYSLFHRLCFNSDLELRYGGDYDLFADVVQKFFESLFVCHICPYVVLDGGCDISDKKLTTLKDRAKEKIQAARSLSLGGGGNVCPLLIREVFIQVLIRLEVCFVQSFSEADRDIMTLANHWNCPVLSSDSDFCIFDLRSGFCSLNSFQWRNLNTIKDTQDYYIPARSFSLNAFCHYFNNMNKALLPLFAVLCGNDHVNLPIMDTFISKVRLPLSSKGRRYHRVLGLLNWLSHFDDPTEALDNVLKSLPKKSRENVKELLCCSMEEYQQSPVKLQDFFQYGSYVCTDASDLGLPEWVLGALAKGQLPPFISDALVLRRTFLHTQVENMQRPNAHRISQPIRQIIYGLLLNGPSHAEDIAQNTLPSQLLAFNEVERIDTNIKTSTVYAKQLLKDQCDLSKLAELPLARRQMLLLEALKVKQVVLESIPTFLKLPIAVTCYWLQSTEAKAKLHHLQALLLGMLREPLHAIVNSPGTEDPQRGGAKMLYEELCQVKAPMRPGPRVDLDTAHVFCQWQSCLQMGLYLNQLLSTPLPEPNLTWLYNGSLVHRLCQQLPASSSVESLLSLCPEAKQLYEHLFNATKSYAPAELFLPKTKSKSKKKRQKKKVASLGTTADAKHWYDRSNRFGPLMPESLEEHVENSELE", "length": 672 }, "evidence": [ { "id": "A0A3L7HNV2", "url": "https://omabrowser.org/oma/group/A0A3L7HNV2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "double-strand break repair via nonhomologous end joining", "id": "GO:0006303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006303", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HNV2", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HNV2" } ], "pmid": "" }, { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HNV2", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HNV2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "3' overhang single-stranded DNA endodeoxyribonuclease activity", "id": "GO:1990599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990599", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HNV2", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HNV2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 499, "end_pos": 501, "annotation": "n_glycosylation_sequon" }, { "start_pos": 606, "end_pos": 608, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3L7HNV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HNV2" }, { "id": "PF00752", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00752" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "XPG N-terminal", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 97, "start_aa": "Met", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 212, "end_pos": 214 }, { "start_pos": 229, "end_pos": 231 }, { "start_pos": 499, "end_pos": 501 }, { "start_pos": 606, "end_pos": 608 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7HP97-1", "uniprot_ac": "A0A3L7HP97", "uniprot_id": "A0A3L7HP97_CRIGR", "mass": { "chemical_mass": 28237.0, "monoisotopic_mass": 28237.0 }, "refseq": { "ac": "XP_003500406", "name": "uncharacterized protein C3orf62 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500406" }, "gene_names": [ { "name": "CUNH3orf62", "type": "recommended", "evidence": [ { "id": "A0A3L7HP97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HP97" } ] }, { "name": "CUNH3orf62", "type": "synonym", "evidence": [ { "id": "XP_003500406", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500406" } ] } ], "protein_names": [ { "name": "Uncharacterized protein C3orf62 homolog", "type": "synonym", "evidence": [ { "id": "A0A3L7HP97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HP97/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C3orf62 homolog", "type": "synonym", "evidence": [ { "id": "XP_003500406", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500406" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613788.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003500406", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500406" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HP97", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HP97" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "CUNH3orf62", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HP97", "locus": {} } ], "crossref": [ { "id": "100764246", "url": "https://www.ncbi.nlm.nih.gov/gene/100764246", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031670", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031670", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764246", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764246", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NWRKDSL", "url": "https://omabrowser.org/oma/group/NWRKDSL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7HP97", "url": "https://www.orthodb.org/?gene=A0A3L7HP97", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR36680", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36680", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR36680:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36680:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15830", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15830", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003500406", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500406", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HP97", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HP97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HP97-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HP97-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEKLRRCRKELTAAIDRAFEGVRHSQECAGPQRLDAPSLASVPVHRLLCRNPLAACPSAAPCAGTSCAPEIESPVFAPHHVPVNAKPLPLYPKRKPLTSKENVLMHSSILARERQFWRAAGDGENWRKESLRKDMERDLKVDSNMLLSSSSQEVTKDLLDMIDHTSIRTIEELAGKLEFENELNRVCGRCQDSPLKEEAWALLVDESPRKALDADPGSLKQAFDDQNIVETVLDLEEDYNLMTSFKYQIE", "length": 251, "header": "tr|A0A3L7HP97-1|A0A3L7HP97_CRIGR Isoform 1 of Uncharacterized protein C3orf62 homolog OS=Cricetulus griseus OX=10029 GN=CUNH3orf62 PE=4 SV=1 CANONICAL=A0A3L7HP97-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HP97-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HP97/entry#A0A3L7HP97-1", "sequence": { "sequence": "MSEKLRRCRKELTAAIDRAFEGVRHSQECAGPQRLDAPSLASVPVHRLLCRNPLAACPSAAPCAGTSCAPEIESPVFAPHHVPVNAKPLPLYPKRKPLTSKENVLMHSSILARERQFWRAAGDGENWRKESLRKDMERDLKVDSNMLLSSSSQEVTKDLLDMIDHTSIRTIEELAGKLEFENELNRVCGRCQDSPLKEEAWALLVDESPRKALDADPGSLKQAFDDQNIVETVLDLEEDYNLMTSFKYQIE", "length": 251, "header": "tr|A0A3L7HP97-1|A0A3L7HP97_CRIGR Isoform 1 of Uncharacterized protein C3orf62 homolog OS=Cricetulus griseus OX=10029 GN=CUNH3orf62 PE=4 SV=1 CANONICAL=A0A3L7HP97-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HP97", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HP97" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HP97", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HP97" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764246", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764246", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B2GUZ1-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 4", "gene_name": "Usp4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEGRGTHERPDVETQKTELGALMGTTLQRGAQWYLIDSRWFKQWKKYVGFDSWDMYNVGEHNLFPGPIDNSGLFSDPESQTLKEHLIDELDYVLVPTEAWNKLLNWYGCVEGQQPIVRKVVEHGLFVKHCKVEVYLLELKLCENSDPTNVLSCHFSKADTIATIEKEMRKLFNIPAERETRLWNKYMSNTYEQLSKLDNTIQDAGLYQGQVLVIEPQNEDGTWPRQTLQSKSSTAPSRNFTTSSKPSASPYSSMSASLIANGDSTNSSGMHNSGVSRGGAGFSASYNCQEPPSPHIQPGLCGLGNLGNTCFMNSALQCLSNTGPLTEYFLKDEYEAEINRDNPLGMKGEIAEAYAELIKQMWSGRDTHVAPRMFKTQVGRFAPQFSGYQQQDSQELLAFILDGLHEDLNRVKKKPYLEPKDANGRPDAVVAKEAWENHRLRNDSVIVDTFHGLFKSTLVCPECAKVSVTFDPFCYLTLPLPLKKDRIMEVFLVPADPHCRPIQYRVTVPLMGAISDLCEALSKLSGIAAENMVVTDVYNHRFHKIFQMDEGLSHITPRDDIFVYEICTTPMDGSEYITLPVYFREKKSRPSSTSSGAVLYGQPLLVSVPKHRLTLESLYQAVCERISRYIKQPLPEEFLSSPLEPGACNGSRGSYEGDEEEMDHQEEGKEQLSEVEESGEDSQGGDPTETTQKAKGPPRHKRLFTFSLVNSCGTADINSLATDGKLLKLNSRSTLAIDWDSETRSLYFDEQESEACEKHTSMSQPQKKKKAAIALRECIELFTTMETLGEHDPWYCPTCKKHQQATKKFDLWSLPKILVVHLKRFSYNRYWRDKLDTVVEFPVRALNMSEFVCDRAARPYVYDLIAVSNHYGAMGVGHYTAYAKNRLNGKWYYFDDSSVSLASEDQIVTKAAYVLFYQRRDDECPSTSSPVSFPGSDGGAKLSSSQQDLGEEEAYTMDTN", "length": 961 }, "evidence": [ { "id": "A0A3L7HP97", "url": "https://omabrowser.org/oma/group/A0A3L7HP97/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6ZUJ4-1", "protein_name": "Uncharacterized protein C3orf62", "gene_name": "C3orf62", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHYIKTWSLLGEMSEKLRRCRKELTAAIDRAFEGVSYSQECTGQQRLELSAAPLSFSLPVHRLLCRRHPLAACSSAAPFAAVPCAPENENPAFATNHAPVNAKPHALCPERKPLTSKENVLMHSSILAPERESWRTAGEGENWRKENLRKDMERDLKADSNMPLNNSSQEVTKDLLDMIDHTSIRTIEELAGKIEFENELNHMCGHCQDSPFKEEAWALLMDKSPQKATDADPGSLKQAFDDHNIVETVLDLEEDYNVMTSFKYQIE", "length": 267 }, "evidence": [ { "id": "A0A3L7HP97", "url": "https://omabrowser.org/oma/group/A0A3L7HP97/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D9C7-1", "protein_name": "Uncharacterized protein C3orf62 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEKLRRCRKELTAAIDRAFEGVRHSQECTAQQRLDAPSLTSQPVHRLLCRNPLAACPSAAPYSGASCAPESENPAFGTHHIPVNSKLQQPLYPKRKPLTSKENVLMQSSILARDRQFWRAAGDGEDWRKDSLRKDMERDLKADPNVLLSSSSQEVTKDLLDMIDHTSIRTIEELAGKLEFENELNRVCGHCQDSPFKEEAWALLVDESPQKALDADPGSLKQALDDQNIVETVLDLEEDYNLMTSFKYQIE", "length": 252 }, "evidence": [ { "id": "A0A3L7HP97", "url": "https://omabrowser.org/oma/group/A0A3L7HP97/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HP97", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HP97" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7HPB6-1", "uniprot_ac": "A0A3L7HPB6", "uniprot_id": "A0A3L7HPB6_CRIGR", "mass": { "chemical_mass": 17991.0, "monoisotopic_mass": 17991.0 }, "refseq": { "ac": "XP_003504284", "name": "transmembrane protein 89", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504284" }, "gene_names": [ { "name": "Tmem89", "type": "recommended", "evidence": [ { "id": "A0A3L7HPB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HPB6" } ] }, { "name": "Tmem89", "type": "synonym", "evidence": [ { "id": "XP_003504284", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504284" } ] } ], "protein_names": [ { "name": "Transmembrane protein 89", "type": "synonym", "evidence": [ { "id": "A0A3L7HPB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HPB6/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 89", "type": "synonym", "evidence": [ { "id": "XP_003504284", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504284" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614047.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003504284", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504284" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HPB6", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HPB6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tmem89", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HPB6", "locus": {} } ], "crossref": [ { "id": "100760698", "url": "https://www.ncbi.nlm.nih.gov/gene/100760698", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028069", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028069", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760698", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760698", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CPGHWMG", "url": "https://omabrowser.org/oma/group/CPGHWMG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7HPB6", "url": "https://www.orthodb.org/?gene=A0A3L7HPB6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR37869", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37869", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37869:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37869:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15098", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15098", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003504284", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504284", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HPB6", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HPB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HPB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HPB6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLYSLFLVPSLSLLVMFVPSHAWSRPLWYQVGLDLQPWGCQPNSLDSCRSSLGCPGYWMTLGGNRIYPVAGITVTTTMMLVITRVMLHRWRSQVTKDPLPPVTSSSCKHWKRQVAVSDRTLVLRVLHMLDAILLHIEGHLQRLASQQQLQIKESPARSG", "length": 159, "header": "tr|A0A3L7HPB6-1|A0A3L7HPB6_CRIGR Isoform 1 of Transmembrane protein 89 OS=Cricetulus griseus OX=10029 GN=Tmem89 PE=4 SV=1 CANONICAL=A0A3L7HPB6-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HPB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HPB6/entry#A0A3L7HPB6-1", "sequence": { "sequence": "MLYSLFLVPSLSLLVMFVPSHAWSRPLWYQVGLDLQPWGCQPNSLDSCRSSLGCPGYWMTLGGNRIYPVAGITVTTTMMLVITRVMLHRWRSQVTKDPLPPVTSSSCKHWKRQVAVSDRTLVLRVLHMLDAILLHIEGHLQRLASQQQLQIKESPARSG", "length": 159, "header": "tr|A0A3L7HPB6-1|A0A3L7HPB6_CRIGR Isoform 1 of Transmembrane protein 89 OS=Cricetulus griseus OX=10029 GN=Tmem89 PE=4 SV=1 CANONICAL=A0A3L7HPB6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HPB6", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HPB6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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"categories": [ "Protein Classification" ] }, { "id": "100755102", "url": "https://www.ncbi.nlm.nih.gov/gene/100755102", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047062", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047062", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755102", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755102", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KGKCCRK", "url": "https://omabrowser.org/oma/group/KGKCCRK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7HPZ2", "url": "https://www.orthodb.org/?gene=A0A3L7HPZ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FX25", "url": "https://www.orthodb.org/?gene=A0A9J7FX25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412:SF418", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412:SF418", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007644218", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644218", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HPZ2", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HPZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HPZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HPZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FX25", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FX25-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FX25-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDNSYDFNEQGSWNGISSGKKKNFLTSEDHGQKILSVLQSFREQNVFYDFKIIMKEEIIPCHRCVLAACSDFFRAMFEVNMKERDDGSVTITNLSSKAVKAFLDYAYTGKARITDDNVEMFFQLSSFLQVPFLSKACSDFLIKSINLVNCLHLLSLSDSYGSTHLFSHALCFVQHHFHLLFKSREFLEMNCGVLEKCLESDELNVPEEEIVLKVVITWIKYNLESRQKHLPHLIRKVRLHQLSEDTLQDCLLNEECLLKSTNCFDIIVDAIKCVQGSSGLFPDARPSTTEKYIFIHKTEENGENQYTFCYNIKTDSWKILPQSHLIDLPGSSLSSYGEKIFLTGGCKGKCCRKVRLHIAESYHDATDQTWCYCPVKNEFFLVSTMKTPRTMHSSVMALNRLFVIGGKTRGSQDIKSLLDVESYDPLSREWTSVSPLPRGIYYPEASACQNVIYVLGSEVEIADAFNPSLDCFFKYNATTDQWSELVAEFGQFFHATLIKAVPVNCTLYICDLSTYKVYSFCPDTCVWKGEGSFECAGFNAGAIGIEDKIYILGGDYAPDEITDEVQVYHSSRSEWEEVSPMPRALTEFYCQVIQFNKYRDPWFSNHF", "length": 607, "header": "tr|A0A3L7HPZ2-1|A0A3L7HPZ2_CRIGR Isoform 1 of Kelch repeat and BTB domain-containing protein 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Kbtbd3 PE=4 SV=1 CANONICAL=A0A3L7HPZ2-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HPZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HPZ2/entry#A0A3L7HPZ2-1", "sequence": { "sequence": "MDNSYDFNEQGSWNGISSGKKKNFLTSEDHGQKILSVLQSFREQNVFYDFKIIMKEEIIPCHRCVLAACSDFFRAMFEVNMKERDDGSVTITNLSSKAVKAFLDYAYTGKARITDDNVEMFFQLSSFLQVPFLSKACSDFLIKSINLVNCLHLLSLSDSYGSTHLFSHALCFVQHHFHLLFKSREFLEMNCGVLEKCLESDELNVPEEEIVLKVVITWIKYNLESRQKHLPHLIRKVRLHQLSEDTLQDCLLNEECLLKSTNCFDIIVDAIKCVQGSSGLFPDARPSTTEKYIFIHKTEENGENQYTFCYNIKTDSWKILPQSHLIDLPGSSLSSYGEKIFLTGGCKGKCCRKVRLHIAESYHDATDQTWCYCPVKNEFFLVSTMKTPRTMHSSVMALNRLFVIGGKTRGSQDIKSLLDVESYDPLSREWTSVSPLPRGIYYPEASACQNVIYVLGSEVEIADAFNPSLDCFFKYNATTDQWSELVAEFGQFFHATLIKAVPVNCTLYICDLSTYKVYSFCPDTCVWKGEGSFECAGFNAGAIGIEDKIYILGGDYAPDEITDEVQVYHSSRSEWEEVSPMPRALTEFYCQVIQFNKYRDPWFSNHF", "length": 607, "header": "tr|A0A3L7HPZ2-1|A0A3L7HPZ2_CRIGR Isoform 1 of Kelch repeat and BTB domain-containing protein 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Kbtbd3 PE=4 SV=1 CANONICAL=A0A3L7HPZ2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FX25-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HPZ2/entry#A0A9J7FX25-1", "sequence": { "sequence": "MFEVNMKERDDGSVTITNLSSKAVKAFLDYAYTGKARITDDNVEMFFQLSSFLQVPFLSKACSDFLIKSINLVNCLHLLSLSDSYGSTHLFSHALCFVQHHFHLLFKSREFLEMNCGVLEKCLESDELNVPEEEIVLKVVITWIKYNLESRQKHLPHLIRKVRLHQLSEDTLQDCLLNEECLLKSTNCFDIIVDAIKCVQGSSGLFPDARPSTTEKYIFIHKTEENGENQYTFCYNIKTDSWKILPQSHLIDLPGSSLSSYGEKIFLTGGCKGKCCRKVRLHIAESYHDATDQTWCYCPVKNEFFLVSTMKTPRTMHSSVMALNRLFVIGGKTRGSQDIKSLLDVESYDPLSREWTSVSPLPRGIYYPEASACQNVIYVLGSEVEIADAFNPSLDCFFKYNATTDQWSELVAEFGQFFHATLIKAVPVNCTLYICDLSTYKVYSFCPDTCVWKGEGSFECAGFNAGAIGIEDKIYILGGDYAPDEITDEVQVYHSSRSEWEEVSPMPRALTEFYCQVIQFNKYRDPWFSNHF", "length": 532, "header": "tr|A0A9J7FX25-1|A0A9J7FX25_CRIGR Computationally mapped isoform of Kelch repeat and BTB domain-containing protein 3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Kbtbd3 PE=4 SV=1 CANONICAL=A0A3L7HPZ2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HPZ2", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HPZ2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HPZ2", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HPZ2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755102", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755102", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TL05-1", "protein_name": "Kelch repeat and BTB domain containing 3", "gene_name": "KBTBD3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDNPNDCSQQSSCNGIPSEKKNNFIVSEDHGQKILSILQNFREQNVFYDFKIIMKDEIIPCHRCVLAACSDFFRAMFEVNMKERDGGSVTITNLSSKAVKAFLDYAYTGKTKITDDNVEMFFQLSSFLQVSFLSKACSDFLIKSINLVNCLQLLSISDSYGSARLFDHALYFVQHHFSLLFKSSDFLEMNFGVLQKCLESDELDVPEEETVLKVVLSWTKHNLESRQKHLPYLIKKVRLYQLSEETLQDCLLNEECLLKSTDCFDIIMDAIKCVQGSGGLFPDARPSTTEKYIFVHKTEENGENQHTFCYNIKSDSWKILPQSHLIDLPGSSLSSYGEKIFLTGGCKGPCCRTVRLHIAESYHDATDQTWCYCPVKNDFFLVSAMKTPRTMHTSVMALNRLFVFGGKTRGSQDIKSLLDVESYNPLSKEWVSVSPLPRGIYYPEASACQNVIYVLGSEVEITDAFNPSLDCFFKYNATTDQWSELVAEFGQFFHATLIKAVPVNCTLYICDLSTYKVYSFCPDTCVWKGEGSFECAGFNAGAVGIEDKIYILGGDYAPDEITDEVQVYHSSRSEWEEVSPMPKALTEFYCQAIQFNKYRDPWFSNHF", "length": 607 }, "evidence": [ { "id": "A0A3L7HPZ2", "url": "https://omabrowser.org/oma/group/A0A3L7HPZ2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AC58HE66-1", "protein_name": "Kelch repeat and BTB domain-containing protein 3 isoform X1", "gene_name": "kbtbd3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCLSSSVCVCVSSSVCVCLLMAVSPQRCVFLRCECVGQQIISVLQGFRQRKLLLDFSIHVQDETLLCHRCVLAACSHFFRAMFELDMRECVDGSVTLSNLSAQAVHTFLDFAYSGEIEVREDNVEMLFQMASFLQVDFLLRSCSDFLLESLDVSNCLHLLELAEGYGSTQLLRGAIDFITQNFQTVSCSVEFLELPSPVLERVLLSDELRVPDEETVLQALLCWVKHDPSTRTSLMQQLLACVRLHHIPIATLENAAQSDMLTDECRNMLTHALAQTQQFSGLFTDARVSTTSTYIFVHKTEESMRHTFCYEIVSDRWTPLPEDAMRILELPGSVMTSFAEKLFISGGCHSDCPRSIRTHISSPHHEATDEFWCYCPIAHSFTPAPRMRHTRTMHTCVVALQRLYVIGGKPRSSRNVPSIVDVDYYDPLMREWISVSPLPKGIYFPEASVCGNVIYALGSEVEFSDAFNPLLDCFFRYDAVADQWSHLVAEFGQFFHARLVKSVCVNETLYLCDLSTYKVYSFCADEGVWKGEGSFECAGFNAAAVGVRGKIFILGGDYSPDEISDEVQVYDSSRSEWQEVSPMPRALTEFHCQVLNFSRYRDPWHSSATGGAEE", "length": 615 }, "evidence": [ { "id": "A0A3L7HPZ2", "url": "https://omabrowser.org/oma/group/A0A3L7HPZ2/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4A7F5-1", "protein_name": "Kelch repeat and BTB domain containing 3", "gene_name": "Kbtbd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKSYNLNEQSSWNGISSEKKKNFLASEDHGQKILSVLQSFREQNVFYDFKIIMKEEIIPCHRCVLAACSDFFRAMFEVNMKERDDGSVTITNLSSKAVKAFLDYAYTGKTRITDDNVEMFFQLSSFLQVSFLSKACSDFLIKSISLVNCLHLLSLSDSYGSAQLFSHTLYFVQHHFHLLFKSRDFLEMNFGVLQKCLESDELNVPEEEMVLKAVLTWIKYNVESRQKHLPHLIAKVRLHQLSEASLQDCLLNEEYLLKSTNCFETIVDAIKRVQGSSGLFPDARPSTTEKYIFIHKTEENGENQYTFCYNIKTDSWKILSQSHLIDLPGSSLSSYGEKIFLTGGCKGKCCRKVRLHIAESYHDATDQTWCYCPIKNEFFFVSTMKTPRTMHTSVTALNRLFVIGGKTRGSQDIKSLLDVESYDPLSKEWTSVSPLPRGIYYPEASACQNVIYVLGSEVEIADAFNPSLDCFFKYNATTDQWSELVAEFGQFFHATLIKAVPVNCTLYICDLSTYKVYSFCPDTCVWKGEGSFECAGFNAGAIGIEDKIYILGGDYAPDEITDEVQVYHSSRSEWEEVSPMPRALTEFYCQIIQFNKYRDPWYSNHF", "length": 607 }, "evidence": [ { "id": "A0A3L7HPZ2", "url": "https://omabrowser.org/oma/group/A0A3L7HPZ2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BHI4-1", "protein_name": "Kelch repeat and BTB domain-containing protein 3", "gene_name": "Kbtbd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDNSYNLNEQSSWNGISSEKKKNYLASEDHGQKILSVLQSFREQNVFYDFKIIMKEEIIPCHRCVLAACSDFFRAMFEVNMKERDDGSVTITNLSSKAVKAFLDYAYTGKTRITDDNVEMFFQLSSFLQVSFLSKACSDFLIKSISLVNCLHLLSLSDSYGSAQLFSHTLYFVQHHFHLLYKSSDFLEMNFGVLQKCLESDELNVPEEEMVLKAVLTWIKYNLESRQKHLPHLITKVRLHQLSEDTLQDYLLNEEYLLKSTNCFDIIVDAIKCVQGSSGLFPDARPSTTEKYIFIHKTEENGENQYTFCYNIKTDSWKILPQSHLIDLPGSSLSSYGEKIFLTGGCKGKCCRRIRLHIAQSYHDATDQTWCYCPAKNEFFCVSAMKTPRTMHTSVMALNRLFVIGGKTRGSQDIKSLLDVESYNPLSREWTSVSPLPRGIYYPEASACQNIIYVLGSEVEIADAFNPSLDCFFKYNATTDQWSELVAEFGQFFHATLIKAVPVNCTLYICDLSTYKVYSFCPDTCVWKGEGSFECAGFNAGAIGIEDKIYILGGDYAPDEITDEVQVYHSSRSEWEEVSPMPRALTEFYCQVIQFNKYRDPWYSNHF", "length": 607 }, "evidence": [ { "id": "A0A3L7HPZ2", "url": "https://omabrowser.org/oma/group/A0A3L7HPZ2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NAB2-1", "protein_name": "Kelch repeat and BTB domain-containing protein 3", "gene_name": "KBTBD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELAMDNSYAFNQRSTCNGIPSEKKNNFLVSEDHGQKILSVLQNFREQNVFYDFKIIMKDEIIPCHRCVLAACSDFFRAMFEVNMKERDDGSVTITNLSSKAVKAFLDYAYTGKTKITDDNVEMFFQLSSFLQVSFLSKACSDFLIKSINLVNCLQLLSISDSYGSTSLFDHALHFVQHHFSLLFKSSDFLEMNFGVLQKCLESDELNVPEEEMVLKVVLSWTKHNLESRQKYLPHLIEKVRLHQLSEETLQDCLFNEESLLKSTNCFDIIMDAIKCVQGSGGLFPDARPSTTEKYIFIHKTEENGENQYTFCYNIKSDSWKILPQSHLIDLPGSSLSSYGEKIFLTGGCKGKCCRTVRLHIAESYHDATDQTWCYCPVKNDFFLVSTMKTPRTMHTSVMALDRLFVIGGKTRGSRDIKSLLDVESYNPLSKEWISVSPLPRGIYYPEASTCQNVIYVLGSEVEITDAFNPSLDCFFKYNATTDQWSELVAEFGQFFHATLIKAVPVNCTLYICDLSTYKVYSFCPDTCVWKGEGSFECAGFNAGAIGIEDKIYILGGDYAPDEITDEVQVYHSNRSEWEEVSPMPRALTEFYCQVIQFNKYRDPWFSNLCA", "length": 612 }, "evidence": [ { "id": "A0A3L7HPZ2", "url": "https://omabrowser.org/oma/group/A0A3L7HPZ2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "R4GMH9-1", "protein_name": "Kelch repeat and BTB domain containing 3", "gene_name": "KBTBD3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MANQRDYISRPICNGISVPENKINSLVAEGHGQQILKVLQKFREQNIFFDFKIIVKDEVIPCHRCVLAACSDFFRAMFEVNMKERDDGNVTISNLSPKAVKAFLDYAYTGKTEITNDNVEMLFQLSSFLQVSLLSKACSDFLIKSIDLVNCLQLLSLSESYGSVRLFDHALDFVQHHFSLLLRSSEFLEMNFEILQKCLEADELNVPEEESVLNAVLQWTKHNIETRQKYLPNLIKKVRLHQLPEKTLQDFLLSEEYLLKSANCSVIINDAVKSVQDFSGLFPDARPSTTEKYIFVHKTDEDGENRYTFCYNIKTDKWKELPHTHMVDLPGSSLSSYGEKIFITGGCKGNCYRTVRLHIAEPFHDATDQTWCYCPVRNEFSIVSAMRKPRTMHTSVVTLNQLFVIGGKTRGAQETRSLLDVESYNPLSKDWKSVSQLPRGIYYPEASACQNIIYVLGSEVEITDAFNPSLDCFFKYNAMTDQWSELVAEFGQFFHATLIKAVPVNCTLYICDLSTYKVYSFCPETCVWKGEGSFECAGFNAGAVGTEDKIYILGGDYAPEEITDEVQVYHSNRSEWEEVSPMPRALTEFYCQVIQFNKYRDPWSSVMTICSGEF", "length": 614 }, "evidence": [ { "id": "A0A3L7HPZ2", "url": "https://omabrowser.org/oma/group/A0A3L7HPZ2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 476, "end_pos": 478, "annotation": "n_glycosylation_sequon" }, { "start_pos": 504, "end_pos": 506, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3L7HPZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HPZ2" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 48, "end_pos": 115, "start_aa": "Tyr", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 476, "end_pos": 478 }, { "start_pos": 504, "end_pos": 506 }, { "start_pos": 93, "end_pos": 95 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], 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REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614047.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003504298", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504298" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HPZ8", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HPZ8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Klhl18", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HPZ8", "locus": {} } ], "crossref": [ { "id": "cd18247", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18247", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18457", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18457", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100765054", "url": "https://www.ncbi.nlm.nih.gov/gene/100765054", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030603", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030603", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DRWTIVT", "url": "https://omabrowser.org/oma/group/DRWTIVT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7HPZ8", "url": "https://www.orthodb.org/?gene=A0A3L7HPZ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412:SF497", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412:SF497", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003504298", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504298", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HPZ8", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HPZ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HPZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HPZ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVEDGAEELEDLVHFSVSELPSRGYGVMEEIRRQGKLCDVTLKIGDHKFSAHRIVLAASIPYFHAMFTNDMMECKQDEIVMQGMDPSALEALINFAYNGNLAIDQQNVQSLLMGASFLQLQSIKDACCTFLRERLHPKNCLGVRQFAETMMCAVLYDAANSFIHQHFVEVSLSEEFLALPLEDVLELVSRDELNVKSEEQVFEAALAWVRYDREKREPCLPELLSNIRLPLCRPQFLSDRVQQDDLVRCCHKCRDLVDEAKDYHLMPERRPHLPAFRTRPRCCTSIAGLIYAVGGLNSAGDSLNVVEVFDPIANRWEKCHPMTTARSRVGVAVVNGLLYAIGGYDGQLRLSTVEAYNPETDTWTRVGSMNSKRSAMGTVVLDGQIYVCGGYDGNSSLNSVETYSPETDKWTVVTPMSSNRSAAGVTIFEGRIYVSGGHDGLQIFNSVEHYNHHTATWHPAASMLNKRCRHGAASLGSKMFVCGGYDGSGFLSIAEMYSSVADQWCLIVPMHTRRSRVSLVASCGRLYAVGGYDGQSNLSSVEMYDPETDRWTFMAPMACHEGGVGVGCIPLLTI", "length": 574, "header": "tr|A0A3L7HPZ8-1|A0A3L7HPZ8_CRIGR Isoform 1 of Kelch-like protein 18 isoform X2 OS=Cricetulus griseus OX=10029 GN=Klhl18 PE=4 SV=1 CANONICAL=A0A3L7HPZ8-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HPZ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HPZ8/entry#A0A3L7HPZ8-1", "sequence": { "sequence": "MVEDGAEELEDLVHFSVSELPSRGYGVMEEIRRQGKLCDVTLKIGDHKFSAHRIVLAASIPYFHAMFTNDMMECKQDEIVMQGMDPSALEALINFAYNGNLAIDQQNVQSLLMGASFLQLQSIKDACCTFLRERLHPKNCLGVRQFAETMMCAVLYDAANSFIHQHFVEVSLSEEFLALPLEDVLELVSRDELNVKSEEQVFEAALAWVRYDREKREPCLPELLSNIRLPLCRPQFLSDRVQQDDLVRCCHKCRDLVDEAKDYHLMPERRPHLPAFRTRPRCCTSIAGLIYAVGGLNSAGDSLNVVEVFDPIANRWEKCHPMTTARSRVGVAVVNGLLYAIGGYDGQLRLSTVEAYNPETDTWTRVGSMNSKRSAMGTVVLDGQIYVCGGYDGNSSLNSVETYSPETDKWTVVTPMSSNRSAAGVTIFEGRIYVSGGHDGLQIFNSVEHYNHHTATWHPAASMLNKRCRHGAASLGSKMFVCGGYDGSGFLSIAEMYSSVADQWCLIVPMHTRRSRVSLVASCGRLYAVGGYDGQSNLSSVEMYDPETDRWTFMAPMACHEGGVGVGCIPLLTI", "length": 574, "header": "tr|A0A3L7HPZ8-1|A0A3L7HPZ8_CRIGR Isoform 1 of Kelch-like protein 18 isoform X2 OS=Cricetulus griseus OX=10029 GN=Klhl18 PE=4 SV=1 CANONICAL=A0A3L7HPZ8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HPZ8", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HPZ8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HPZ8", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HPZ8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1T4E0-1", "protein_name": "Kelch like family member 18", "gene_name": "KLHL18", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVEDGAEELEDLVHFSVSELPSRGYGVMEEIRRQGKLCDVTLKIGDHKFSAHRIVLAASIPYFHAMFTNDMMECKQDEIVMQGMDPSALEALINFAYNGHLAIDQQNVQSLLMGASFLQLQSIKDACCTFLRERLHPKNCLGVRQFAETMMCAVLYDAANSFIHQHFVEVSMSEEFLALPLEDVLELVSRDELNVKSEEQVFEAALAWVRYDREQRGPYLPELLSNIRLPLCRPQFLSDRVQQDDLVRCCHKCRDLVDEAKDYHLMPERRPHLPAFRTRPRCCTSIAGLIYAVGGLNSAGDSLNVVEVFDPIANRWEKCHPMTTARSRVGVAVVNGLLYAIGGYDGQLRLSTVEVYNPETDTWTRVGSMNSKRSAMGTVVLDGQIYVCGGYDGNSSLNSVETYSPETDKWTVVTPMSSNRSAAGVTVFEGRIYVSGGHDGLQIFNSVEHYNHHTATWHSAAGMLNKRCRHGAASLGSKMFVCGGYDGSGFLSIAEVYSSVADQWCLIVPMHTRRSRVSLVASCGRLYAVGGYDGQSNLSSVEMYDPDTDRWTFMAPMACHEGGVGVGCIPLLTI", "length": 574 }, "evidence": [ { "id": "A0A3L7HPZ8", "url": "https://omabrowser.org/oma/group/A0A3L7HPZ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5ZLS4-1", "protein_name": "Kelch-like family member 18", "gene_name": "Klhl18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVEDGAEELEDLVHFSVSELPSRGYGVMEEIRRQGKLCDVTLKIGDHKFSAHRIVLAASIPYFHAMFTNDMMECKQDEIVMQGMDPSALEALINFAYNGNLAIDQQNVQSLLMGASFLQLQSIKDACCTFLRERLHPKNCLGVRQFAETMMCAVLYDAANSFIHQHFVEVSLSEEFLALPLEDVLELLSRDELNVKSEEQVFEAALAWIRYDREQRGPCLPELLSNIRLPLCRPQFLSDRVQQDDLVRCCHKCRDLVDEAKDYHLMPERRPHLPAFRTRPRCCTSIAGLIYAVGGLNSAANFYAGDSLNVVEVFDPIANRWEKCHPMTTARSRVGVAVVNGLLYAIGGYDGQLRLSTVEAYNPETDTWTRVGSMNSKRSAMGTVVLDGQIYVCGGYDGNSSLNSVETYSPETDKWTVVTPMSSNRSAAGVTVFEGRIYVSGGHDGLQIFSSVEQYNHHTATWHPAASMLNKRCRHGAASLGSKMFVCGGYDGSGFLSIAEMYSSVADQWCLIVPMHTRRSRVSLVASCGRLYAVGGYDGQSNLSSVEMYDPETDRWTFMAPMACHEGGVGVGCIPLLTI", "length": 579 }, "evidence": [ { "id": "A0A3L7HPZ8", "url": "https://omabrowser.org/oma/group/A0A3L7HPZ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9Q4F2-1", "protein_name": "Kelch-like protein 18", "gene_name": "Klhl18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVEDGAEELEDLVHFSVSELPSRGYGVMEEIRRQGKLCDVTLKIGDHKFSAHRIVLAASIPYFHAMFTNDMMECKQDEIVMQGMDPSALEALINFAYNGNLAIDQQNVQSLLMGASFLQLQSIKDACCTFLRERLHPKNCLGVRQFAETMMCAVLYDAANSFIHQHFVEVSLSEEFLALPLEDVLELVSRDELNVKSEEQVFEAALAWVRYDREQRGPCLPELLSNIRLPLCRPQFLSDRVQQDDLVRCCHKCRDLVDEAKDYHLMPERRPHLPAFRTRPRCCTSIAGLIYAVGGLNSAGDSLNVVEVFDPIANRWEKCHPMTTARSRVGVAVVNGLLYAIGGYDGQLRLSTVEAYNPETDTWTRVGSMNSKRSAMGTVVLDGQIYVCGGYDGNSSLNSVETYSPETDKWTVVTPMSSNRSAAGVTVFEGRIYVSGGHDGLQIFSSVEHYNHHTATWHPAASMLNKRCRHGAASLGSKMFVCGGYDGSGFLSIAEMYSSVADQWCLIVPMHTRRSRVSLVASCGRLYAVGGYDGQSNLSSVEMYDPETDRWTFMAPMACHEGGVGVGCIPLLTI", "length": 574 }, "evidence": [ { "id": "A0A3L7HPZ8", "url": "https://omabrowser.org/oma/group/A0A3L7HPZ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O94889-1", "protein_name": "Kelch-like protein 18", "gene_name": "KLHL18", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVEDGAEELEDLVHFSVSELPSRGYGVMEEIRRQGKLCDVTLKIGDHKFSAHRIVLAASIPYFHAMFTNDMMECKQDEIVMQGMDPSALEALINFAYNGNLAIDQQNVQSLLMGASFLQLQSIKDACCTFLRERLHPKNCLGVRQFAETMMCAVLYDAANSFIHQHFVEVSMSEEFLALPLEDVLELVSRDELNVKSEEQVFEAALAWVRYDREQRGPYLPELLSNIRLPLCRPQFLSDRVQQDDLVRCCHKCRDLVDEAKDYHLMPERRPHLPAFRTRPRCCTSIAGLIYAVGGLNSAGDSLNVVEVFDPIANCWERCRPMTTARSRVGVAVVNGLLYAIGGYDGQLRLSTVEAYNPETDTWTRVGSMNSKRSAMGTVVLDGQIYVCGGYDGNSSLSSVETYSPETDKWTVVTSMSSNRSAAGVTVFEGRIYVSGGHDGLQIFSSVEHYNHHTATWHPAAGMLNKRCRHGAASLGSKMFVCGGYDGSGFLSIAEMYSSVADQWCLIVPMHTRRSRVSLVASCGRLYAVGGYDGQSNLSSVEMYDPETDCWTFMAPMACHEGGVGVGCIPLLTI", "length": 574 }, "evidence": [ { "id": "A0A3L7HPZ8", "url": "https://omabrowser.org/oma/group/A0A3L7HPZ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VGE5-1", "protein_name": "Kelch-like protein diablo", "gene_name": "KLHL18", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDLSDNSQVEDQYFVYKHDKLFGESFPLFKEIRRMGKLCDVTLKVEDQTFSAHRVVLAATIPYFYAMFTNNMAESRIKEITMKESAIEPSALESLINYVYSGQVRIDNQNVQNLMVGASFLQLSNVRDACASFLISRFHPHNVLGIRTFADSMICRQLIDAADKYIDQNFAKVSQSEEFLALDCEQLLELMRRDELNVRTEEVIFEACMKWVKYAEDKRSELFPQVLAAVRLPLLSPQFLADRVAREELIRSSHQCRDLLDEAKDFHLMPERRGLLQSFRTRQRSGEFFTGQIYAVGGLASTGESVSTVEIYDPLTKKWKMGEQMSMMRSRVGVAVLNGKLYAFGGFNGTERLSTVEVYDPRKNKWSQGCAMLCKRSAVGVAALDDCIYVCGGYDGVTSLNTVEVYYPKSNTWKTVAQMMKYRSAGGVTQLNGYVYALGGHDGLSIFDSVERYDQAEDVWVKMSPMLNRRCRLGVATLNGKIYVCGGYCGNSFLRSVECYDPQTDTWKLVTPMNCKRSRVALAANMGKLWAIGGYDGESNLSTVEVYDPETDKWTFMPPMCAHSGGVGAGVIRIE", "length": 575 }, "evidence": [ { "id": "A0A3L7HPZ8", "url": "https://omabrowser.org/oma/group/A0A3L7HPZ8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HPZ8", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HPZ8" } ], "pmid": "" }, { "name": "positive regulation of mitotic cell cycle phase transition", "id": "GO:1901992", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901992", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HPZ8", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HPZ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 394, "end_pos": 396, "annotation": "n_glycosylation_sequon" }, { "start_pos": 419, "end_pos": 421, "annotation": "n_glycosylation_sequon" }, { "start_pos": 537, "end_pos": 539, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3L7HPZ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HPZ8" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 38, "end_pos": 105, "start_aa": "Cys", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 394, "end_pos": 396 }, { "start_pos": 419, "end_pos": 421 }, { "start_pos": 537, "end_pos": 539 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7HQ00-1", "uniprot_ac": "A0A3L7HQ00", "uniprot_id": "A0A3L7HQ00_CRIGR", "mass": { "chemical_mass": 36125.0, "monoisotopic_mass": 36125.0 }, "refseq": { "ac": "XP_027269950", "name": "cilia- and flagella-associated protein 73", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269950" }, "gene_names": [ { "name": "Cfap73", "type": "recommended", "evidence": [ { "id": "A0A3L7HQ00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQ00" } ] }, { "name": "Cfap73", "type": "synonym", "evidence": [ { "id": "XP_027269950", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269950" } ] } ], "protein_names": [ { "name": "Cilia- and flagella-associated protein 73", "type": "synonym", "evidence": [ { "id": "A0A3L7HQ00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQ00/entry#names_and_taxonomy" } ] }, { "name": "cilia- and flagella-associated protein 73", "type": "synonym", "evidence": [ { "id": "XP_027269950", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027269950" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. 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Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 197 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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} ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 24% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614660.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003509205", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509205" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HQV7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQV7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tex55", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQV7", "locus": {} } ], "crossref": [ { "id": "cd22975", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22975", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100760908", "url": "https://www.ncbi.nlm.nih.gov/gene/100760908", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR040760", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040760", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048377", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048377", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760908", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760908", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QPCKFEP", "url": "https://omabrowser.org/oma/group/QPCKFEP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7HQV7", "url": "https://www.orthodb.org/?gene=A0A3L7HQV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47110", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47110", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47110:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47110:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF17819", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17819", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003509205", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509205", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HQV7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HQV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQV7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDEPPQEAPNGSLDNKDTAQSPNNQKTYIEEGAGQDPHTGSENTGVGSSEQTSDKASSQTANEGSGWTDPRTSEEASQPSEHRGTSQQIDRRSSGQTERKTSETYNQQLPSLFEGKAYEKTDDRASLPFGGKAFEQTDQGTWEFGDQTSSDQADYRTSGRSQYQVYNEVDYLPEDFSGQHRFSGDQERDYRDYVRMKRDAQMADYRSYYKTLAQTENRSLSEIVDNKEVREADFKIQPCTFEVSQTDLRSKVSASWETESAATVQGYKPPEAEFTTDTQSSYGKLPSITTKVYYSSSQEKAQTTELPTDVVAEFEQRKSSQRQSEDSKRLFPPIVFEDPYQVALRYMEKHNILQIFQQITENLVYEKPDDPLDFMLGQVQDMIRHRDQHRII", "length": 392, "header": "tr|A0A3L7HQV7-1|A0A3L7HQV7_CRIGR Isoform 1 of Testis-specific expressed protein 55 OS=Cricetulus griseus OX=10029 GN=Tex55 PE=4 SV=1 CANONICAL=A0A3L7HQV7-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HQV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQV7/entry#A0A3L7HQV7-1", "sequence": { "sequence": "MDEPPQEAPNGSLDNKDTAQSPNNQKTYIEEGAGQDPHTGSENTGVGSSEQTSDKASSQTANEGSGWTDPRTSEEASQPSEHRGTSQQIDRRSSGQTERKTSETYNQQLPSLFEGKAYEKTDDRASLPFGGKAFEQTDQGTWEFGDQTSSDQADYRTSGRSQYQVYNEVDYLPEDFSGQHRFSGDQERDYRDYVRMKRDAQMADYRSYYKTLAQTENRSLSEIVDNKEVREADFKIQPCTFEVSQTDLRSKVSASWETESAATVQGYKPPEAEFTTDTQSSYGKLPSITTKVYYSSSQEKAQTTELPTDVVAEFEQRKSSQRQSEDSKRLFPPIVFEDPYQVALRYMEKHNILQIFQQITENLVYEKPDDPLDFMLGQVQDMIRHRDQHRII", "length": 392, "header": "tr|A0A3L7HQV7-1|A0A3L7HQV7_CRIGR Isoform 1 of Testis-specific expressed protein 55 OS=Cricetulus griseus OX=10029 GN=Tex55 PE=4 SV=1 CANONICAL=A0A3L7HQV7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HQV7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQV7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HQV7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HQV7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760908", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760908", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1SZZ2-1", "protein_name": "Testis expressed 55", "gene_name": "TEX55", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": 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"MDEPPDESLNHENTTRAPDNEKNNIEGAGQALHRGSEHAGVGSSEPTGDKVSGQANAGSRQTGRRTSEEAEQRSSQPTEHRLPGHAERRASQQAERRLSERRTSQPPNQQLPSHSERKTSGKIDGQESLLSEQTDQETSEFDDLIPSASTDYLSARSQQQEYNQHGYWTEDSSDPHRLSEDLEKDYTRVKHITEKQAGYRSYYKTLAHIESRTLTDTNDYRETGQRLQPCTFEDSEAELPSKVSTTEETESATTIQAYNTQDTELTTSTSHEKLPSITTKVYYSSSPEKIQTTEYTSDTTPVFDQGRSSQRSSQSSRWRFPPIVFEDPYHVALRYVEKHNILHIFQQITENLVYERPDDPLYFMLDQVQNMIKHRDERQSD", "length": 381 }, "evidence": [ { "id": "A0A3L7HQV7", "url": "https://omabrowser.org/oma/group/A0A3L7HQV7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96M34-1", "protein_name": "Testis-specific expressed protein 55", "gene_name": "TEX55", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509649" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614741.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003509649", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509649" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HRD2", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRD2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Fam131a", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRD2", "locus": {} } ], "crossref": [ { "id": "100770285", "url": "https://www.ncbi.nlm.nih.gov/gene/100770285", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026782", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026782", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770285", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770285", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ACISQVV", "url": "https://omabrowser.org/oma/group/ACISQVV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7HRD2", "url": "https://www.orthodb.org/?gene=A0A3L7HRD2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MC75", "url": "https://www.orthodb.org/?gene=A0A8C2MC75", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15736", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15736", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15736:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15736:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003509649", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509649", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HRD2", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRD2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HRD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRD2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MC75", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MC75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MC75-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPMISVLGKMFLWQREGPGGRWTCQTSRRVASDPAWAVEWIELPRGLSLSSLGSARTLRGWSRSPRPSSVDSQDLPEVNVGDTVAMLPKSRRALTIQEIAALARSSLHGISQVVKDHVTKPTAMAQGRVAHLIEWKGWSKPSDSPAALESAFSSYSDLSEGEQEARFAAGVAEQFAIAEAKLRAWSSVDGDDSTDDSYDEDFTGGIDTDMAGPLGTHLQDLFTGRRFSRPVRQGSVEPESDCSQTVSPDTLCSSLCSLEDGLLGSPARMTSQMLGEELLLARLPPSRESAFRSLGPLEAQDSLYNSPLTESCLSPTEEEPDSCKDHPLLCPLPVGSWERQQQVSDVASSGVVSLDEDEVEPEDQ", "length": 364, "header": "tr|A0A3L7HRD2-1|A0A3L7HRD2_CRIGR Isoform 1 of Protein FAM131A isoform X2 OS=Cricetulus griseus OX=10029 GN=Fam131a PE=3 SV=1 CANONICAL=A0A3L7HRD2-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HRD2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRD2/entry#A0A3L7HRD2-1", "sequence": { "sequence": "MPMISVLGKMFLWQREGPGGRWTCQTSRRVASDPAWAVEWIELPRGLSLSSLGSARTLRGWSRSPRPSSVDSQDLPEVNVGDTVAMLPKSRRALTIQEIAALARSSLHGISQVVKDHVTKPTAMAQGRVAHLIEWKGWSKPSDSPAALESAFSSYSDLSEGEQEARFAAGVAEQFAIAEAKLRAWSSVDGDDSTDDSYDEDFTGGIDTDMAGPLGTHLQDLFTGRRFSRPVRQGSVEPESDCSQTVSPDTLCSSLCSLEDGLLGSPARMTSQMLGEELLLARLPPSRESAFRSLGPLEAQDSLYNSPLTESCLSPTEEEPDSCKDHPLLCPLPVGSWERQQQVSDVASSGVVSLDEDEVEPEDQ", "length": 364, "header": "tr|A0A3L7HRD2-1|A0A3L7HRD2_CRIGR Isoform 1 of Protein FAM131A isoform X2 OS=Cricetulus griseus OX=10029 GN=Fam131a PE=3 SV=1 CANONICAL=A0A3L7HRD2-1" }, "locus": {} }, { "isoform_ac": "A0A8C2MC75-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRD2/entry#A0A8C2MC75-1", "sequence": { "sequence": "MLPKSRRALTIQEIAALARSSLHGISQVVKDHVTKPTAMAQGRVAHLIEWKGWSKPSDSPAALESAFSSYSDLSEGEQEARFAAGVAEQFAIAEAKLRAWSSVDGDDSTDDSYDEDFTGGIDTDMAGPLGTHLQDLFTGRRFSRPVRQGSVEPESDCSQTVSPDTLCSSLCSLEDGLLGSPARMTSQMLGEELLLARLPPSRESAFRSLGPLEAQDSLYNSPLTESCLSPTEEEPDSCKDHPLLCPLPVGSWERQQQVSDVASSGVVSLDEDEVEPEDQ", "length": 279, "header": "tr|A0A8C2MC75-1|A0A8C2MC75_CRIGR Computationally mapped isoform of Protein FAM131A isoform X1 OS=Cricetulus griseus OX=10029 GN=Fam131a PE=3 SV=1 CANONICAL=A0A3L7HRD2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HRD2", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRD2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HRD2", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRD2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770285", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770285", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1UIP4-1", "protein_name": "Family with sequence similarity 131 member A", "gene_name": "FAM131A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPMISVLGKMFLWQREGPGGRWTCQTSRRVASDPAWAVEWIELPRGLSLSSLGSARTLRGWSRSSRPSSVDSQDLPEVNVGDTVAMLPKSRRALTIQEIAALARSSLHGISQVVKDHVTKPTAMAQGRVAHLIEWKGWSKPSDSPTALESAFSSYSDLSEGEQEARFAAGVAEQFAIAEAKLRAWSSVDGEDSTDESYDEDFVGGTDSDLAGQLPLGPHLQDLFTGHRFSRPMRQGSVEPESDCSQTVSPETLCSSLCSLEDGLLGSPARLASQLLGDELLLAKLPPSRESAFRSLGPLEAQDSLYNSPLTESCLSPAEEEPAPCKDCQPLCPPPAGSWERQRQASDVASSGVVSLDEDEVEPEEQ", "length": 366 }, "evidence": [ { "id": "A0A3L7HRD2", "url": "https://omabrowser.org/oma/group/A0A3L7HRD2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0Z912-1", "protein_name": "Family with sequence similarity 131 member A", "gene_name": "FAM131A", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGCIGSKTTIVAVDTTLCVEWKEVKALSPLRAARPAPLPRLLRQASFDSQDFLEVNVEDTVEMLPKSRRALTIQEIAALARSSLHGISQVVKEHVTKPTAMAQGRVAHLIEWKGWCKPVEPPTALESAFNSYCHLSEGEQEARFAAGVAEQFAIAEAKLRAWSSVDGDDSNDESYDEDFMPSSESSLPAEHHPGAALLRDLLRGHLCQLGARHGSCEPESDSSHTLSPKTLCSSLCSLEMVSPSELTAKLLGSLGGELPPPSSQSALRGLVWPRCQDSLSPMPYAEACLSPAEDEVVLSKDFALRRKISDVASSGVVSLEEEDEEEEEEEEEDEAEEP", "length": 338 }, "evidence": [ { "id": "A0A3L7HRD2", "url": "https://omabrowser.org/oma/group/A0A3L7HRD2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4ADK8-1", "protein_name": "Family with sequence similarity 131, member A", "gene_name": "Fam131a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPMISVLGKMFLWQREGPGGRWTCQTSRRVASDPAWAVEWIELPRGLSLSSLGSARTLRGWSRSPRPSSVDSQDLPEVNVGDTVAMLPKSRRALTIQEIAALARSSLHGISQVVKDHVTKPTAMAQGRVAHLIEWKGWSKPSDSPAALESAFSSYSDLSEGEQEARFAAGVAEQFAIAEAKLRAWSSVDGDDSTDDSYDEDFTGGADTDMAGPLGSHLQDLFTGRRFSRPVRQGSVEPESDCSQTVSPDTLCSSLCSLEDGLLGSPARMTSQMLGEELLLARLPPSRESAFRSLGPLEAQDSLYNSPLSESCLSPAEEEPDSCKDCQLLCPLPTGSWERQQQVSEVASSGVASLDEDEVDQ", "length": 361 }, "evidence": [ { "id": "A0A3L7HRD2", "url": "https://omabrowser.org/oma/group/A0A3L7HRD2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MJN3-1", "protein_name": "Family with sequence similarity 131 member A", "gene_name": "FAM131A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPMISVLGKMFLWQREGPGGRWTCQTSRRVASDPAWAVEWIELPRGLSLSSLGSARTLRGWSRSSRPSSVDSQDLPEVNVGDTIAMLPKSRRALTIQEIAALARSSLHGISQVVKDHVTKPTAMAQGRVAHLIEWKGWSKPSDSPAALESAFSSYSDLSEGEQEARFAAGVAEQFAIAEAKLRAWSSVDGEDSTDESYDEDFAGGTDSDLTGQMPLGPHLQDLFTGHRFSRPVRQGSVEPESDCSQTVSPETLCSSLCSLEDGLLGSPARLASQLLGDELLLAKLPPSRESAFRSLGPLEAQDSLYNSPLTESCLSPAEEEPAPCKDCQPLCLPPVSSWERQRQASDVASSGVVSLDEDEVEPEEQ", "length": 366 }, "evidence": [ { "id": "A0A3L7HRD2", "url": "https://omabrowser.org/oma/group/A0A3L7HRD2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6UXB0-3", "protein_name": "Protein FAM131A", "gene_name": "FAM131A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPMISVLGKMFLWQREGPGGRWTCQTSRRVSSDPAWAVEWIELPRGLSLSSLGSARTLRGWSRSSRPSSVDSQDLPEVNVGDTVAMLPKSRRALTIQEIAALARSSLHGISQVVKDHVTKPTAMAQGRVAHLIEWKGWSKPSDSPAALESAFSSYSDLSEGEQEARFAAGVAEQFAIAEAKLRAWSSVDGEDSTDDSYDEDFAGGMDTDMAGQLPLGPHLQDLFTGHRFSRPVRQGSVEPESDCSQTVSPDTLCSSLCSLEDGLLGSPARLASQLLGDELLLAKLPPSRESAFRSLGPLEAQDSLYNSPLTESCLSPAEEEPAPCKDCQPLCPPLTGSWERQRQASDLASSGVVSLDEDEAEPEEQ", "length": 366 }, "evidence": [ { "id": "A0A3L7HRD2", "url": "https://omabrowser.org/oma/group/A0A3L7HRD2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BWU3-1", "protein_name": "Protein FAM131A", "gene_name": "Fam131a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPMISVLGKMFLWQREGPGGRWTCQTSRRVASDPAWAVEWIELPRGLSLSSLGSARTLRGWSRSPRPSSVDSQDLPEVNVGDTVAMLPKSRRALTIQEIAALARSSLHGISQVVKDHVTKPTAMAQGRVAHLIEWKGWSKPSDSPAALESAFSSYSDLSEGEQEARFAAGVAEQFAIAEAKLRAWSSVDGDDSTDDSYDEDFTGGIDTDMAGPLGSHLQDLFTGRRFSRPVRQGSVEPESDCSQTVSPDTLCSSLCSLEDGLLGSPARMTSQLLGEELLLARLPPSRESAFRSLGPLEAQDSLYNSPLSESCLSPAEEEPDSCKDCQLLCPLPTGSWERQQQVSDVASSGVVSLDEDEVDQ", "length": 361 }, "evidence": [ { "id": "A0A3L7HRD2", "url": "https://omabrowser.org/oma/group/A0A3L7HRD2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7HRK6-1", "uniprot_ac": "A0A3L7HRK6", "uniprot_id": "A0A3L7HRK6_CRIGR", "mass": { "chemical_mass": 40231.0, "monoisotopic_mass": 40231.0 }, "refseq": { "ac": "XP_027268505", "name": "leucine-rich repeat-containing protein 58 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268505" }, "gene_names": [ { "name": "Lrrc58", "type": "recommended", "evidence": [ { "id": "A0A3L7HRK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRK6" } ] }, { "name": "Lrrc58", "type": "synonym", "evidence": [ { "id": "XP_027268505", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268505" } ] } ], "protein_names": [ { "name": "Leucine-rich repeat-containing protein 58 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A3L7HRK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRK6/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat-containing protein 58 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027268505", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268505" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. 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Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035300566", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300566" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HRL2", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRL2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Slc7a4", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRL2", "locus": {} } ], "crossref": [ { "id": "100757506", "url": "https://www.ncbi.nlm.nih.gov/gene/100757506", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002293", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002293", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029485", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029485", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757506", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757506", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3L7HRL2", "url": "https://www.orthodb.org/?gene=A0A3L7HRL2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43243", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43243", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43243:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43243:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13906", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13906", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035300566", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300566", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HRL2", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HRL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRL2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARGLPSTASLARFCQKLNRLKPLEESSMETSLRRCLSTLDLTLLGVGGMVGSGLYVLTGTVAKDMAGPAVLLSFLVAAVASLLAALCYAEFGARVPRTGSAYLFTYVSMGEIWAFLIGWNVLLEYLIGGAAVARAWSGYLDAIFNHSIRNFTESHMGVWQMPFLAHYPDFLAAGILLVASAFVSCGARVSSWLNHTFSAISMIVILLIIILGFILARPHNWSAEEGGFAPFGFSGILAGTATCFYAFVGFDVIAASSEEAKNPRWAVPMAIAISLGLAAGAYILVSTVLTLMVPWHSLDPDSALADAFYRRGYSWAGFIVAVGSICAMNTVLLSNLFSLPRIVYAMAADGLFFQMFARVHPRTQVPVVGILVFGVLMALLALLLDLEALVQFLSIGTLLAYTFVATSIIVLRFQKVSPPSSPCLASPGHTAKKYDSFSDHIQLVGGTQNSMSEPGQLRPALKPFLGFLNGCRPGTAVAWALGILVASAISLACVLVFGNSDLHLPRWGYVLLLVVSGSVFLFSLLVLGAHQQQKQQDTFQIPLVPLTPALSILLNICLMLKLSYLTWLRFIFWLLVGLVVYFGYGVWHSKENQREPLELTTAHYVVFPSSSLEETVQAVQPAGQAAVQESACAE", "length": 635, "header": "tr|A0A3L7HRL2-1|A0A3L7HRL2_CRIGR Isoform 1 of Cationic amino acid transporter 4 isoform X2 OS=Cricetulus griseus OX=10029 GN=Slc7a4 PE=4 SV=1 CANONICAL=A0A3L7HRL2-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HRL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HRL2/entry#A0A3L7HRL2-1", "sequence": { "sequence": "MARGLPSTASLARFCQKLNRLKPLEESSMETSLRRCLSTLDLTLLGVGGMVGSGLYVLTGTVAKDMAGPAVLLSFLVAAVASLLAALCYAEFGARVPRTGSAYLFTYVSMGEIWAFLIGWNVLLEYLIGGAAVARAWSGYLDAIFNHSIRNFTESHMGVWQMPFLAHYPDFLAAGILLVASAFVSCGARVSSWLNHTFSAISMIVILLIIILGFILARPHNWSAEEGGFAPFGFSGILAGTATCFYAFVGFDVIAASSEEAKNPRWAVPMAIAISLGLAAGAYILVSTVLTLMVPWHSLDPDSALADAFYRRGYSWAGFIVAVGSICAMNTVLLSNLFSLPRIVYAMAADGLFFQMFARVHPRTQVPVVGILVFGVLMALLALLLDLEALVQFLSIGTLLAYTFVATSIIVLRFQKVSPPSSPCLASPGHTAKKYDSFSDHIQLVGGTQNSMSEPGQLRPALKPFLGFLNGCRPGTAVAWALGILVASAISLACVLVFGNSDLHLPRWGYVLLLVVSGSVFLFSLLVLGAHQQQKQQDTFQIPLVPLTPALSILLNICLMLKLSYLTWLRFIFWLLVGLVVYFGYGVWHSKENQREPLELTTAHYVVFPSSSLEETVQAVQPAGQAAVQESACAE", "length": 635, "header": "tr|A0A3L7HRL2-1|A0A3L7HRL2_CRIGR Isoform 1 of Cationic amino acid transporter 4 isoform X2 OS=Cricetulus griseus OX=10029 GN=Slc7a4 PE=4 SV=1 CANONICAL=A0A3L7HRL2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Classification" ] }, { "id": "A0A3L7HSW0", "url": "https://www.orthodb.org/?gene=A0A3L7HSW0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR25462", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25462", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR25462:SF299", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25462:SF299", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003495532", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495532", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HSW0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HSW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HSW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HSW0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESAMCVCSPCCTWQRCCPRLFSCLCCKFIFTAERNCTCFPCPYKDERNCQFCHCTCAENPNCHWCCCSWANDPNCKCCCTSNTNMKCYYYESRCCHNAIITFRRGRLRTLRISSKTALRIGSSETQLEELKSMTPSNNLVSHLTCPMCNRLRLHSFMLPCNHSLCEKCLRQLQKHAEVTENFFILICPMCNRSHCMPYSHQTHLPENYLRGRLTKRYMQQHGYLKWRFDRSSGPILCQVCRTRRIAYKRCITCRLNLCNECLKAFHSDVAMQDHVFVDTSAEDQDEKICIHHPSSRINEYCRSDNQLLCAFCKIAFHNGHDTVSLIDACSERSAALFSAIAKFKAVRYEIDNDLMEFNILKSSFKADKEAKRKEIRSGFLKLRAILQEKEKLIMEQIENLEVSRQKEIEKYVNITTMKVNEMDGLIAYSKEALKETGQVAFLQSAKILVDQIEEGIQNTFRPDPQLRLHSLQCIPLDFAELSSAIHELFPTGPKKACSSGDSLPSQYPIHSEMMIARKVTFSTHSFGNQQIYQRSSSLLSFSATNDKAKMEAFGRAQSTAPVRPTDGLYTYWSATGETQPPQNSNSFHNWYSFNDTSVKTPGPIVIYQTLVYPRAAKVYWTCPTEDVDSFEMEFYELINTPPNNVRTELCGQIRDIMQQNLELHNLTPNTEYLFKVRAINDNGPGQWSDICKVVTPDGRGKNRAKWGLLKNIQSALQKRF", "length": 721, "header": "tr|A0A3L7HSW0-1|A0A3L7HSW0_CRIGR Isoform 1 of Tripartite motif-containing protein 42 OS=Cricetulus griseus OX=10029 GN=Trim42 PE=4 SV=1 CANONICAL=A0A3L7HSW0-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HSW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HSW0/entry#A0A3L7HSW0-1", "sequence": { "sequence": "MESAMCVCSPCCTWQRCCPRLFSCLCCKFIFTAERNCTCFPCPYKDERNCQFCHCTCAENPNCHWCCCSWANDPNCKCCCTSNTNMKCYYYESRCCHNAIITFRRGRLRTLRISSKTALRIGSSETQLEELKSMTPSNNLVSHLTCPMCNRLRLHSFMLPCNHSLCEKCLRQLQKHAEVTENFFILICPMCNRSHCMPYSHQTHLPENYLRGRLTKRYMQQHGYLKWRFDRSSGPILCQVCRTRRIAYKRCITCRLNLCNECLKAFHSDVAMQDHVFVDTSAEDQDEKICIHHPSSRINEYCRSDNQLLCAFCKIAFHNGHDTVSLIDACSERSAALFSAIAKFKAVRYEIDNDLMEFNILKSSFKADKEAKRKEIRSGFLKLRAILQEKEKLIMEQIENLEVSRQKEIEKYVNITTMKVNEMDGLIAYSKEALKETGQVAFLQSAKILVDQIEEGIQNTFRPDPQLRLHSLQCIPLDFAELSSAIHELFPTGPKKACSSGDSLPSQYPIHSEMMIARKVTFSTHSFGNQQIYQRSSSLLSFSATNDKAKMEAFGRAQSTAPVRPTDGLYTYWSATGETQPPQNSNSFHNWYSFNDTSVKTPGPIVIYQTLVYPRAAKVYWTCPTEDVDSFEMEFYELINTPPNNVRTELCGQIRDIMQQNLELHNLTPNTEYLFKVRAINDNGPGQWSDICKVVTPDGRGKNRAKWGLLKNIQSALQKRF", "length": 721, "header": "tr|A0A3L7HSW0-1|A0A3L7HSW0_CRIGR Isoform 1 of Tripartite motif-containing protein 42 OS=Cricetulus griseus OX=10029 GN=Trim42 PE=4 SV=1 CANONICAL=A0A3L7HSW0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 566, "start_aa": "Thr", "end_pos": 566, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr566", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HSW0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HSW0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HSW0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HSW0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759091", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759091", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BCX4-1", "protein_name": "Tripartite motif containing 42", "gene_name": "TRIM42", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDTAMCVCSPCCTWQRCCPRLCSCLCCKFLFTSERNCTCFPCPYKDERNCQFCHCTCSENPNCHWCCCSWANDPNCKCCCTASSNLKCYYYESRCCRNATITFRKGRLRSIRTSSKTALRIGSSDTQLEEVKMMPTANSNLVSHLSCPICGRLRLHSFMLPCHHSLCEKCLRRLQKHAEVTENFFILICPVCNRSHCMSYSHKMQLPENYLRGRLTKRYMQQHGYLKWRFDRSSGPIVCQVCRSQRIAYKRCLTCRLNLCNECLKTFHSDVAMQDHVFVDTSTEDQDEKICIHHPSSRIIEYCRNDNELLCGFCKTSLHNGHDTISLIDACSERAAALFSAIAKFKAVRYEIDNDLMEFNILKNSFKADKEVKRKEIRNGFLKLRSILQEKEKTIMEQIENLEVSRQKEIEKYVYVTTMKVNEMDGLIAYSKEALKETGQVAFLQSAKILVDQIEDGIQSTYRPDPQLRLHSLNCMPLDFAELSSAIHELFPTGPKKVCSSGDSLPSPYPLQSEMMIARKVTFSTHSFNNQQIYQRSSSLLSFNAPACEKTKIGLEAYGRAQSAAPAKPTDGLYTYWSAGVENQPVQNSNSFHNWYSFNDSSVQTPGPIIIYQTLVYPRAAKVYWTCPTEDVDSFEMEFYELITSPPNNVRTELCGQIRDIMQQNLELHNLTPNTEYLFKVRAINDNGPGQWSDICKVVTPDGRGKNRAKWGLLKNIQTALQKRF", "length": 725 }, "evidence": [ { "id": "A0A3L7HSW0", "url": "https://omabrowser.org/oma/group/A0A3L7HSW0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8IWZ5-1", "protein_name": "Tripartite motif-containing protein 42", "gene_name": "TRIM42", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METAMCVCCPCCTWQRCCPQLCSCLCCKFIFTSERNCTCFPCPYKDERNCQFCHCTCSESPNCHWCCCSWANDPNCKCCCTASSNLNCYYYESRCCRNTIITFHKGRLRSIHTSSKTALRTGSSDTQVDEVKSIPANSHLVNHLNCPMCSRLRLHSFMLPCNHSLCEKCLRQLQKHAEVTENFFILICPVCDRSHCMPYSNKMQLPENYLHGRLTKRYMQEHGYLKWRFDRSSGPILCQVCRNKRIAYKRCITCRLNLCNDCLKAFHSDVAMQDHVFVDTSAEEQDEKICIHHPSSRIIEYCRNDNKLLCTFCKFSFHNGHDTISLIDACSERAASLFSAIAKFKAVRYEIDNDLMEFNILKNSFKADKEAKRKEIRNGFLKLRSILQEKEKIIMEQIENLEVSRQKEIEKYVYVTTMKVNEMDGLIAYSKEALKETGQVAFLQSAKILVDQIEDGIQTTYRPDPQLRLHSINYVPLDFVELSSAIHELFPTGPKKVRSSGDSLPSPYPVHSETMIARKVTFSTHSLGNQHIYQRSSSMLSFSNTDKKAKVGLEACGRAQSATPAKPTDGLYTYWSAGADSQSVQNSSSFHNWYSFNDGSVKTPGPIVIYQTLVYPRAAKVYWTCPAEDVDSFEMEFYEVITSPPNNVQMELCGQIRDIMQQNLELHNLTPNTEYVFKVRAINDNGPGQWSDICKVVTPDGHGKNRAKWGLLKNIQSALQKHF", "length": 723 }, "evidence": [ { "id": "A0A3L7HSW0", "url": "https://omabrowser.org/oma/group/A0A3L7HSW0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D2H5-1", "protein_name": "Tripartite motif-containing protein 42", "gene_name": "Trim42", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METAMCVCSPCCTWQRCCPRLFSCLCCKFIFTSERNCTCFPCPYKDERNCQFCHCTCAENPNCHWCCCSWANDPNCKCCCTASTNLKCYYYESHCCRNVTITFRKGRLRSIVTSSKTALRVGSSDTQMDEPKTMPASSHLVSHLTCPMCNRLRLHSFMLPCNHSLCEKCLRQLQKHAEVTENFFILICPMCSRSHCMPYSHQMHLPENYLRGRLTKRYMQQHGYLKWRFDRSSGPILCQVCRTRRIAYKRCVTCRLNLCNDCLKAFHSDVAMQDHVFVDTSAEDQDEKICIHHPSSRINEYCRSDNQLLCAFCKIAFHNGHDTVSLIDACSERSAALFSAIAKFKAVRYEIDNDLMEFNILKSSFKADKEAKRKEVRNGFLKLRAILQEKEKIIMEQIENLEVSRQKEIEKYVYITTMKVNEMDGLIAYSKEALKETGQVAFLQSAKILVDQIEEGIQNTFRPDPQLRLHSLHCIPLDFAELSNAIHELFPTGPKKACSSGDSLPSQYPIHSEMMIARKVTFSTHSFGNQQIYQRSSSLISFNTANDKGKMGLENYGRAQSAAPAKTTDGLYTYWSATGETQPPQSSNSFHNWYSFNDTSVRTPGPIVIYQTLVYPRAAKVYWTCPTEDVDSFEMEFYELVTTPPNNVRTELCGQIRDILQQNLELHNLTPNTEYLFKVRAINDNGPGQWSDICKVVTPDGRGKNRAKWGLLKNIQSALQKRF", "length": 723 }, "evidence": [ { "id": "A0A3L7HSW0", "url": "https://omabrowser.org/oma/group/A0A3L7HSW0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HSW0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HSW0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HSW0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HSW0" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HSW0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HSW0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HSW0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HSW0" } ], "pmid": "" }, { "name": "positive regulation of type I interferon-mediated signaling pathway", "id": "GO:0060340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060340", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HSW0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HSW0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" }, { "start_pos": 414, "end_pos": 416, "annotation": "n_glycosylation_sequon" }, { "start_pos": 595, "end_pos": 597, "annotation": "n_glycosylation_sequon" }, { "start_pos": 666, "end_pos": 668, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3L7HSW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HSW0" }, { "id": "PS50119", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50119" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B box-type", "eco_id": "ECO_0000259", "start_pos": 285, "end_pos": 326, "start_aa": "Gln", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A3L7HSW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HSW0" }, { "id": "PS51262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "COS", "eco_id": "ECO_0000259", "start_pos": 434, "end_pos": 492, "start_aa": "Leu", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A3L7HSW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HSW0" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 601, "end_pos": 699, "start_aa": "Thr", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A3L7HSW0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HSW0" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 146, "end_pos": 192, "start_aa": "Cys", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 566 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 162, "end_pos": 164 }, { "start_pos": 192, "end_pos": 194 }, { "start_pos": 36, "end_pos": 38 }, { "start_pos": 414, "end_pos": 416 }, { "start_pos": 595, "end_pos": 597 }, { "start_pos": 666, "end_pos": 668 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": 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"mass": { "chemical_mass": 20032.0, "monoisotopic_mass": 20032.0 }, "refseq": { "ac": "XP_007643501", "name": "small acidic protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643501" }, "gene_names": [ { "name": "C3H11orf58", "type": "recommended", "evidence": [ { "id": "A0A3L7HU95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HU95" } ] }, { "name": "C3H11orf58", "type": "synonym", "evidence": [ { "id": "XP_007643501", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643501" } ] } ], "protein_names": [ { "name": "Small acidic protein", "type": "recommended", "evidence": [ { "id": "A0A3L7HU95", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HU95/entry#names_and_taxonomy" } ] }, { "name": "small acidic protein", "type": "synonym", "evidence": [ { "id": "XP_007643501", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643501" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614088.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007643501", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643501" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HU95", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HU95" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "C3H11orf58", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HU95", "locus": {} } ], "crossref": [ { "id": "100756062", "url": "https://www.ncbi.nlm.nih.gov/gene/100756062", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026714", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026714", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028124", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028124", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756062", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756062", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DIGSSNW", "url": "https://omabrowser.org/oma/group/DIGSSNW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7HU95", "url": "https://www.orthodb.org/?gene=A0A3L7HU95", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22175", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22175", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22175:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22175:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15477", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15477", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007643501", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643501", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HU95", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HU95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HU95-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HU95-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSAARESHPHGVKRSASPDDDLGSSNWEAADLGNEERKQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDDSPDAESPDDSDSDSESEKEESAEELHATEHPDDAEDPKSKKDAKSNYKMMFVKSSGS", "length": 181, "header": "tr|A0A3L7HU95-1|A0A3L7HU95_CRIGR Isoform 1 of Small acidic protein OS=Cricetulus griseus OX=10029 GN=C3H11orf58 PE=3 SV=1 CANONICAL=A0A3L7HU95-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HU95-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HU95/entry#A0A3L7HU95-1", "sequence": { "sequence": "MSAARESHPHGVKRSASPDDDLGSSNWEAADLGNEERKQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDDSPDAESPDDSDSDSESEKEESAEELHATEHPDDAEDPKSKKDAKSNYKMMFVKSSGS", "length": 181, "header": "tr|A0A3L7HU95-1|A0A3L7HU95_CRIGR Isoform 1 of Small acidic protein OS=Cricetulus griseus OX=10029 GN=C3H11orf58 PE=3 SV=1 CANONICAL=A0A3L7HU95-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HU95", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HU95" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HU95", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HU95" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756062", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756062", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LGJ9-1", "protein_name": "Small acidic protein", "gene_name": "C1h11orf58", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAARESHPHGVKRSASPDDDLGSSNWEAADLGNEERKQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDEDDSPDAESPDDSDSDSESEKEESAEELHAAAHPDDTEDPKSKKDAKSSYKMMFVKSSGS", "length": 181 }, "evidence": [ { "id": "A0A3L7HU95", "url": "https://omabrowser.org/oma/group/A0A3L7HU95/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O00193-1", "protein_name": "Small acidic protein", "gene_name": "SMAP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSAARESHPHGVKRSASPDDDLGSSNWEAADLGNEERKQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVEDHDGEGDVAGDDDDDDDDSPDPESPDDSESDSESEKEESAEELQAAEHPDEVEDPKNKKDAKSNYKMMFVKSSGS", "length": 183 }, "evidence": [ { "id": "A0A3L7HU95", "url": "https://omabrowser.org/oma/group/A0A3L7HU95/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3MHL8-1", "protein_name": "Small acidic protein", "gene_name": "SMAP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSAARESHPHGVKRSASPDDDLGSSNWEAADLGNEERKQKFLRLMGAGKKEHTGRLVIGDHKSTSHFRTGEEDKKINEELESQYQQSMDSKLSGRYRRHCGLGFSEVDDHDGEGDVAGDDDDDDSPDPESPDDSESDSESEKEESTEELQAAEHPDEVEDSKNKKDAKSNYKMMFVKSSGS", "length": 181 }, "evidence": [ { "id": "A0A3L7HU95", "url": 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predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613583.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035292643", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035292643" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HUK5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HUK5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Sdr42e1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HUK5", "locus": {} } ], "crossref": [ { "id": "100752182", "url": "https://www.ncbi.nlm.nih.gov/gene/100752182", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050177", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050177", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752182", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752182", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IGAYKRS", "url": "https://omabrowser.org/oma/group/IGAYKRS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7HUK5", "url": "https://www.orthodb.org/?gene=A0A3L7HUK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43245", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43245", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43245:SF51", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43245:SF51", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01073", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01073", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035292643", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035292643", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HUK5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HUK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HUK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HUK5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSPRFSEETVLITGGGGYFGFRLGCALNQKGVRVILFDISQPAQNLPEGIRFIRGDICCLSDVEMAFRDTDIACVFHVASYGMSGREQLNKTLIEEVNVGGTNNILQTCLERGVPRLVYTSTVNVVFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEKKVLEADGSAFKQGNGVLRTCALRPAGIYGVGEQRHLPRIVSYIERGLFRFIFGDPNSLVEFVHVDNLVKAHILASEALKADKGHVASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPSIRLPFTLIYCFAFLVEMTHFILSRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYEPQPFDLQEVVEWFKVQGHGRRSGGQDSEFILWDGILVLLLALSLLTWFPPSTVLNL", "length": 393, "header": "tr|A0A3L7HUK5-1|A0A3L7HUK5_CRIGR Isoform 1 of Short-chain dehydrogenase/reductase family 42E member 1 OS=Cricetulus griseus OX=10029 GN=Sdr42e1 PE=3 SV=1 CANONICAL=A0A3L7HUK5-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HUK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HUK5/entry#A0A3L7HUK5-1", "sequence": { "sequence": "MDSPRFSEETVLITGGGGYFGFRLGCALNQKGVRVILFDISQPAQNLPEGIRFIRGDICCLSDVEMAFRDTDIACVFHVASYGMSGREQLNKTLIEEVNVGGTNNILQTCLERGVPRLVYTSTVNVVFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEKKVLEADGSAFKQGNGVLRTCALRPAGIYGVGEQRHLPRIVSYIERGLFRFIFGDPNSLVEFVHVDNLVKAHILASEALKADKGHVASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPSIRLPFTLIYCFAFLVEMTHFILSRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYEPQPFDLQEVVEWFKVQGHGRRSGGQDSEFILWDGILVLLLALSLLTWFPPSTVLNL", "length": 393, "header": "tr|A0A3L7HUK5-1|A0A3L7HUK5_CRIGR Isoform 1 of Short-chain dehydrogenase/reductase family 42E member 1 OS=Cricetulus griseus OX=10029 GN=Sdr42e1 PE=3 SV=1 CANONICAL=A0A3L7HUK5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HUK5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HUK5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HUK5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HUK5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752182", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752182", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JT58-1", "protein_name": "Short chain dehydrogenase/reductase family 42E, member 1", "gene_name": "Sdr42e1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSPRFPEETVLITGGGGYFGFRLGCALNQKGVRVILFDIIEPAQNLPEGITFVRGDIRCLSDVEAAFQDADIACVFHIASYGMSGREQLNKTRIEEVNVGGTENILQACLGRGVPSLVYTSTFNVIFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEKKVLEANGLAFKQGDGVLRTCAIRPAGIYGAGEQRHLPRVVSYIERGLFRFVYGDPQSLVEFVHVDNLAKAHILASEALKADKGHIASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPTTRLPLTLIYYFAFLIEMTHLIVGRLYNFQPFLTCTEVYKTGVTHYFSLEKAKSELGYAPQPFDLQEVVEWFKAHGHGRRPRGQDSEFILWDGILVLLLAFSVLTWIPPSTILSL", "length": 393 }, "evidence": [ { "id": "A0A3L7HUK5", "url": "https://omabrowser.org/oma/group/A0A3L7HUK5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A287A6U6-1", "protein_name": "Short chain dehydrogenase/reductase family 42E, member 1", "gene_name": "SDR42E1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDSPRSPKETVLITGGGGYFGFRLGCALNQKGLRVILFDVSSPAHTIPEGVKFIRGDIRLLADVERAFEDADVTCVFHIASYGMSGREQLNRSRIEDVNVGGTDNVLQACRSRGVPRLVYTSTFNVIFGGQVIRNGDESLPYLPLHLHPDHYSRTKSVAEKKVLEANGTALARRAGVLRTCALRPAGIYGPGEQRHLPRIVSYLEKGLFRFVYGDPKSLVEFVHVDNLVQAHILASEALKADKGHVASGQPYFISDGRPVNNFEFFRPLVEGLGYKFPSVRLPLPLIYFFAFLTEMAYFLLGRLYNFQPFLTRTEVYKTAVTHYFSLEKAKKELGYEAQPFDLQEVVEWFKAHGHGRSPGRQDSEFSLVWYGLLVSLLIIAVLTWLPPSVILSL", "length": 394 }, "evidence": [ { "id": "A0A3L7HUK5", "url": "https://omabrowser.org/oma/group/A0A3L7HUK5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0Y0K1-1", "protein_name": "Short chain dehydrogenase/reductase family 42E, member 1", "gene_name": "SDR42E1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEAGSSAKETVLITGGGGYFGFRLGCTIYKKGVDVILFDVTKPLQPVPEGIKFMQGNVCCLAEVEEALKDVICVFHIASYGMSGREQLNRKLIEDVNVKGTENVIQACKSTGVSSLVYTSTYNVIFGGQIIENGDESLPYLPLHLHPDHYSRTKSLAEMKVLKANGTELGNGKGVLRTCALRPAGIYGPGEQRHLPRIVSYIERGLFKFVYGDPLSLVEFVHVDNLVQAHILAFEALKANKKHIAAGQAYFISDGRPVNNFEFFRPLVEGLGYKFPTCRLPLSLVYFFAFLTEVVHLLVGHVYNFQPLLTRTEVYKTGVTHYFSMEKARKELGYEPQKYSLNEVVEWFRSQGCGPKPRKYTITHLLRDGGLLLLFIAVLVSWFPPAVIFSP", "length": 391 }, "evidence": [ { "id": "A0A3L7HUK5", "url": "https://omabrowser.org/oma/group/A0A3L7HUK5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A8DZE7-1", "protein_name": "Short-chain dehydrogenase/reductase family 42E member 1", "gene_name": "sdr42e1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEVNRKDNSFLITGGGGYFGFRLACALLKTSSKVVLFDVSPPIQDLPEGLIFMRADIRDYAQVEKAVRGSHCVFHIASYGMSGREQLNRKLIEEVNVKGTENILRACVAHSVPRLIYTSTFNVVFGGQEIKNGDESLPYLPLHLHPDHYSRTKSIAEMQVLKANNLALSNSTGVLRTCALRPAGIYGPGEQRHLPRIVSYIENGIFRFVYGDPDSLVEFVHVDNLVSAHLLAADALTEKQQCRAAGQAYFISDGRPVNNFEFFRPLVEGLGYSFPTLRLPISMIYFFAFLTEMVHFVVGRIYNFQPLLTRTEVYKTGVTHYFSMRKAREELGYEPKLYDLEDVVQWFQARGHGKKRSRSSIRKLILDVFVVVAFVAVLLSCLPVVGQ", "length": 387 }, "evidence": [ { "id": "A0A3L7HUK5", "url": "https://omabrowser.org/oma/group/A0A3L7HUK5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q32L94-1", "protein_name": "Short-chain dehydrogenase/reductase family 42E member 1", "gene_name": "SDR42E1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDSHKSPKETVLITGGGGYFGFRLGCALNLLGVHVILFDISHPAQTIPEGIRFILGDIRCLSDIENAFQGVDVACVFHIASYGMSGREQLNRSLIEEINVGGTDNILQACRRRGVPRLVYTSTFNVIFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEKKVLSANGTALERGGGVLSTCALRPAGIYGPGEQRHLPRIVSYIEKGLFRFVYGDPKSLVEFVHVDNLVQAHILASEALKANKGHIAAGQPYFISDGRPVNNFEFFRPLVEGLGYKFPSTRLPLTLIYCFAFLTEMTHFILGRLYNFQPFLTRTEVYKTGVTHYFSLEKARKELGYEAQPFDLQEAVEWFKAHGHGRRPGSCDSKCLVWDGLVILLVVTVVLVWLLPSVILSM", "length": 393 }, "evidence": [ { "id": "A0A3L7HUK5", "url": "https://omabrowser.org/oma/group/A0A3L7HUK5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8WUS8-1", "protein_name": "Short-chain dehydrogenase/reductase family 42E member 1", "gene_name": "SDR42E1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPKRSQKESVLITGGSGYFGFRLGCALNQNGVHVILFDISSPAQTIPEGIKFIQGDIRHLSDVEKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVYTSTFNVIFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLDRGDGVLRTCALRPAGIYGPGEQRHLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHILASEALRADKGHIASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPSTRLPLTLVYCFAFLTEMVHFILGRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYKAQPFDLQEAVEWFKAHGHGRSSGSRDSECFVWDGLLVFLLIIAVLMWLPSSVILSL", "length": 393 }, "evidence": [ { "id": "A0A3L7HUK5", "url": "https://omabrowser.org/oma/group/A0A3L7HUK5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D665-1", "protein_name": "Short-chain dehydrogenase/reductase family 42E member 1", "gene_name": "Sdr42e1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSPRFPEETVLITGGGGYFGFRLGCALNQKGARVILFDITQPAQNLPEGIKFVCGDIRCLADVETAFQDAEKVACVFHVASYGMSGREQLNKTQIEEVNVGGTENILRACLERGVPRLVYTSTFNVIFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEKKVLEANGLAFKQGDGILRTCAIRPAGIYGAGEQRHLPRIVSYIERGLFRFVYGDPQSLVEFVHVDNLAKAHILASEALKADKGHVASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPSTRLPLTLIYCLAFLVEMTHFIVGRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGFEPQPFDLQEVVEWFKAHGHGRGAAGQDSEFMLWDGILILLLALSVLTWILPSTTLSI", "length": 394 }, "evidence": [ { "id": "A0A3L7HUK5", "url": "https://omabrowser.org/oma/group/A0A3L7HUK5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "steroid biosynthetic process", "id": "GO:0006694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006694", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HUK5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HUK5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor", "id": "GO:0016616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016616", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HUK5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HUK5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3L7HUK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HUK5" }, { "id": "PF01073", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01073" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "3-beta hydroxysteroid dehydrogenase/isomerase", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 283, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 91, "end_pos": 93 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7HUQ4-1", "uniprot_ac": "A0A3L7HUQ4", "uniprot_id": "A0A3L7HUQ4_CRIGR", "mass": { "chemical_mass": 31649.0, "monoisotopic_mass": 31649.0 }, "refseq": { "ac": "XP_027267697", "name": "out at first protein homolog isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267697" }, "gene_names": [ { "name": "Oaf", "type": "recommended", "evidence": [ { "id": "A0A3L7HUQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HUQ4" } ] }, { "name": "Oaf", "type": "synonym", "evidence": [ { "id": "XP_027267697", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267697" } ] } ], "protein_names": [ { "name": "Out at first protein homolog", "type": "recommended", "evidence": [ { "id": "A0A3L7HUQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HUQ4/entry#names_and_taxonomy" } ] }, { "name": "out at first protein homolog isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027267697", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267697" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027267697", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267697" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HUQ4", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HUQ4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Oaf", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HUQ4", "locus": {} } ], "crossref": [ { "id": "100765087", "url": "https://www.ncbi.nlm.nih.gov/gene/100765087", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053897", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053897", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765087", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765087", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3L7HUQ4", "url": "https://www.orthodb.org/?gene=A0A3L7HUQ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13423", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13423", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13423:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13423:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14941", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14941", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22873", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22873", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027267697", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267697", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HUQ4", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HUQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HUQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HUQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRPPGRCDVPSARPALPPLLLLLLSPLLLGAPRGVGAGSSVPAELRVRVRLPDGQVTEESLQADSDADSISLELRKPDGTLISFTADFKKDVKIFRALILGELEKGQSQFQGLCFVTRLHHNEIIPSEAMAKLRQKNPRAVRQAEEVRGLEQLHMDIAVNFSQGGLLSPHLHNVCAEATDAIYTRQEDVQFWMERGVDSSVFEALPKEQMELPRCGQVRDRGKPCACRYSLSLAWYPCMLKYCHSRDRPAPYKCGIRSCRKNYSFDFYVPQRQLCLWDEDP", "length": 281, "header": "tr|A0A3L7HUQ4-1|A0A3L7HUQ4_CRIGR Isoform 1 of Out at first protein homolog OS=Cricetulus griseus OX=10029 GN=Oaf PE=3 SV=1 CANONICAL=A0A3L7HUQ4-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HUQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HUQ4/entry#A0A3L7HUQ4-1", "sequence": { "sequence": "MRPPGRCDVPSARPALPPLLLLLLSPLLLGAPRGVGAGSSVPAELRVRVRLPDGQVTEESLQADSDADSISLELRKPDGTLISFTADFKKDVKIFRALILGELEKGQSQFQGLCFVTRLHHNEIIPSEAMAKLRQKNPRAVRQAEEVRGLEQLHMDIAVNFSQGGLLSPHLHNVCAEATDAIYTRQEDVQFWMERGVDSSVFEALPKEQMELPRCGQVRDRGKPCACRYSLSLAWYPCMLKYCHSRDRPAPYKCGIRSCRKNYSFDFYVPQRQLCLWDEDP", "length": 281, "header": "tr|A0A3L7HUQ4-1|A0A3L7HUQ4_CRIGR Isoform 1 of Out at first protein homolog OS=Cricetulus griseus OX=10029 GN=Oaf PE=3 SV=1 CANONICAL=A0A3L7HUQ4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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{ "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7HUW1-1", "uniprot_ac": "A0A3L7HUW1", "uniprot_id": "A0A3L7HUW1_CRIGR", "mass": { "chemical_mass": 27612.0, "monoisotopic_mass": 27612.0 }, "refseq": { "ac": "XP_027264087", "name": "ADP-ribosylation factor-like protein 10 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264087" }, "gene_names": [ { "name": "Arl10", "type": "recommended", "evidence": [ { "id": "A0A3L7HUW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HUW1" } ] }, { "name": "Arl10", "type": "synonym", "evidence": [ { "id": "XP_027264087", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264087" } ] } ], "protein_names": [ { "name": "ADP-ribosylation factor-like protein 10 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027264087", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264087" } ] }, { "name": "ADP-ribosylation factor-like protein 10 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A3L7HUW1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HUW1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 267 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613681.1) and transcript sequence (IACG01091614.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027264087.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027264087", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264087" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HUW1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HUW1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Arl10", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HUW1", "locus": {} } ], "crossref": [ { "id": "100768218", "url": "https://www.ncbi.nlm.nih.gov/gene/100768218", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006689", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006689", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042951", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042951", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768218", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768218", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3L7HUW1", "url": "https://www.orthodb.org/?gene=A0A3L7HUW1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47575", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47575", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47575:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47575:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00025", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00025", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027264087", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264087", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HUW1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HUW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HUW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HUW1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPRPLRPLVLALGGAAAVLGSVLFILWKAYFGRGRERRWDRGEAWWGAESARFPQWDEWEPEDEEDERALEELEQREVLVLGLDGSGKSTFLRMLSGKPPLEGHVPTWGFNSVRLPTKNFEVDLLEIGGSQNLRFYWKEFVNEVDVLVFMLDSSDRPRLPRARQELQKLLDRDPDLPVVIVANKQDLSGAMSMVELQRELGLLASYNQREIFLLAASIAPAGSTFEEPGTVHIWKLLLELLS", "length": 243, "header": "tr|A0A3L7HUW1-1|A0A3L7HUW1_CRIGR Isoform 1 of ADP-ribosylation factor-like protein 10 isoform X2 OS=Cricetulus griseus OX=10029 GN=Arl10 PE=4 SV=1 CANONICAL=A0A3L7HUW1-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HUW1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HUW1/entry#A0A3L7HUW1-1", "sequence": { "sequence": "MAPRPLRPLVLALGGAAAVLGSVLFILWKAYFGRGRERRWDRGEAWWGAESARFPQWDEWEPEDEEDERALEELEQREVLVLGLDGSGKSTFLRMLSGKPPLEGHVPTWGFNSVRLPTKNFEVDLLEIGGSQNLRFYWKEFVNEVDVLVFMLDSSDRPRLPRARQELQKLLDRDPDLPVVIVANKQDLSGAMSMVELQRELGLLASYNQREIFLLAASIAPAGSTFEEPGTVHIWKLLLELLS", "length": 243, "header": "tr|A0A3L7HUW1-1|A0A3L7HUW1_CRIGR Isoform 1 of ADP-ribosylation factor-like protein 10 isoform X2 OS=Cricetulus griseus OX=10029 GN=Arl10 PE=4 SV=1 CANONICAL=A0A3L7HUW1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616698.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003514586", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514586" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HVW9", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HVW9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tigd3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HVW9", "locus": {} } ], "crossref": [ { "id": "100767431", "url": "https://www.ncbi.nlm.nih.gov/gene/100767431", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006600", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006600", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767431", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767431", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PGLCHVR", "url": "https://omabrowser.org/oma/group/PGLCHVR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7HVW9", "url": "https://www.orthodb.org/?gene=A0A3L7HVW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19303", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19303", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19303:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19303:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03184", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03184", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03221", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03221", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04218", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04218", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003514586", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514586", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HVW9", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HVW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HVW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HVW9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELNTKKKLHALSLAEKIQVLELLDESKMSQSEVARRFQVSQPQISRICKNKEKLLADWCSGTANHERKRKRESKYSGIDEALLCWYHIARAKAWDVTGPMLLHKAKELADIMGQDFVPSIGWLVRWKRRNNVGFGARQVLVPLFPPEPPPPGLLSQVQPPLSLKDFSPEDVFGCAEVPLLYRAVPGRVLACDRLQVLLCANSRGTEKRRVFVGGLQAAPRCFFGVNSEALPASYHPDLAIPWSEWLAQFDQDMGQQGRQVALLLAAGVAEEWASLPGLHHVRLLPLSASSTTPSLPGSVVLAFKAHYRHRLLSKLAAMQRGRKGTSLADARANITVLDALHMVAAAWAKVSPQLILSSFIHEGLAPGKTAPSLNKDTEMSPVPSGLSQEEFSHFVDLEDEDPGPRVCKEETGTEDIGREEDGFESLPTKADALRALCTLRRWLECNSTSPEPFEKFYDCEVEVEQLCCL", "length": 470, "header": "tr|A0A3L7HVW9-1|A0A3L7HVW9_CRIGR Isoform 1 of Tigger transposable element-derived protein 3 OS=Cricetulus griseus OX=10029 GN=Tigd3 PE=4 SV=1 CANONICAL=A0A3L7HVW9-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HVW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HVW9/entry#A0A3L7HVW9-1", "sequence": { "sequence": "MELNTKKKLHALSLAEKIQVLELLDESKMSQSEVARRFQVSQPQISRICKNKEKLLADWCSGTANHERKRKRESKYSGIDEALLCWYHIARAKAWDVTGPMLLHKAKELADIMGQDFVPSIGWLVRWKRRNNVGFGARQVLVPLFPPEPPPPGLLSQVQPPLSLKDFSPEDVFGCAEVPLLYRAVPGRVLACDRLQVLLCANSRGTEKRRVFVGGLQAAPRCFFGVNSEALPASYHPDLAIPWSEWLAQFDQDMGQQGRQVALLLAAGVAEEWASLPGLHHVRLLPLSASSTTPSLPGSVVLAFKAHYRHRLLSKLAAMQRGRKGTSLADARANITVLDALHMVAAAWAKVSPQLILSSFIHEGLAPGKTAPSLNKDTEMSPVPSGLSQEEFSHFVDLEDEDPGPRVCKEETGTEDIGREEDGFESLPTKADALRALCTLRRWLECNSTSPEPFEKFYDCEVEVEQLCCL", "length": 470, "header": "tr|A0A3L7HVW9-1|A0A3L7HVW9_CRIGR Isoform 1 of Tigger transposable element-derived protein 3 OS=Cricetulus griseus OX=10029 GN=Tigd3 PE=4 SV=1 CANONICAL=A0A3L7HVW9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HVW9", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HVW9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HVW9", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HVW9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767431", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767431", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZS21-1", "protein_name": "Tigger transposable element derived 3", "gene_name": "Tigd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELNTKKKLHALSLAEKIQVLELLDESKMSQSEVARRFQVSQPQISRICKNKEKLLADWCSGTANHERKRKRESKYSGIDEALLCWYHIARAKAWDVTGPMLLHKAKELADIMGQDFVPSIGWLVRWKRRNNVGFGTRQVLVPLLPPEPPPAVSPSQAQPPLSLKDFSPEDVFGCAEVPLLYRAVPGRVFECDRLQVLLCANSRGTEKRRVFVGGLQPAPRCFFGVNSEALPASYHPDLAIPWSEWLAQFDQDMGQQGRQVALLLASGVVEEWASPPGLHHVRLLPLSTSSTTPSLPGSVVLAFKAHYRHRLLSKLAAMQSGKEGTSRAEARANITVLDALHMVAAAWAKVPRQLILTSFIQEGLAPGKTPLSLDKDTEMSPVPSGLSQEEFSHFVDLEDEDPGPRVCKEETSTEDNGREEDGFESLPTKADALRALCTLRRWLECNSTSPELFEKFYDCEVEVEQLCCL", "length": 470 }, "evidence": [ { "id": "A0A3L7HVW9", "url": "https://omabrowser.org/oma/group/A0A3L7HVW9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MZ31-1", "protein_name": "Tigger transposable element derived 3", "gene_name": "TIGD3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MELCGKKKLHALSLAEKIQVLELLDESKMSQSEVARRFQVSQPQISRICKNKEKLLADWCSGTANRERKRKRESKYSGIDEALLCWYHIARAKAWDVTGPMLLHKAKELADILGQDFVPSIGWLVRWKRRNNVGFGARHILAPPFPPEPPPPAPTPQAQLPLSLKDFSPEDIFGCVEVPLLYRAVPGRAGTCDRVQVLLCANSRGTEKRRLLVCGPQAAPRCFFGVSSEALPASYHPDLAIPWSEWLSQFDRDMGRQGRQVALLMAAQVVEEVAGLPGLCHVRLLPLSAASPTQPLPSSVVRAFKAHYRRRLLSKLAAAQSERACTLLAEIGAGITVLDALHMAAAAWAKVPLQLIVSSFIQEGLAPGKTPVAQDQASEVLQVPGGLSLEEFSRFVDLESEEPVSGACKEEVGPADEAGGGEDGFEPLPTKADALQALGTLRRWLECSGTTPELFENFYACEEGVERLCCL", "length": 471 }, "evidence": [ { "id": "A0A3L7HVW9", "url": "https://omabrowser.org/oma/group/A0A3L7HVW9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RRI0-1", "protein_name": "Tigger transposable element derived 3", "gene_name": "TIGD3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MELCSKKKLHALSLAEKIQVLELLDESKMSQSEVARRFQVSQPQISRICKNKEKLLADWCSGTANRERKRKRESKYSGIDEALLCWYHIARAKAWDVTGPMLLHKAKELADIMGQDFVPSIGWLVRWKRRNNVGFGARHVLVPPLPPEPPPPAPTPQAQLPLSLKDFSPEDIFGCAEVPLLYRAVPGRVGTRDRVQVLLCANSRGTEKRRVLVSGLQAAPRCFFGVSSEALLASYHPDLVIPWSEWLAQFDRDMGQQGRQVALLLAARVVEELVGLPRLCHVRLLPLSAASTTPSLPSSVVRAFKAHYRHRLLGKLAAAQSERAGPSLAAAGAAITVLDALHMAAAAWAKVPLQLIVSSFVQEGLAPGTTPPDPDKASEMPPVPGGLSLEEFSRFVDLEGEEAMSGVCKEEVSPEGEEGHGEDGFEPLPTKADALRALSTLRRWFECNGTSPELFENFYACEEGVERLCCL", "length": 471 }, "evidence": [ { "id": "A0A3L7HVW9", "url": "https://omabrowser.org/oma/group/A0A3L7HVW9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6B0B8-1", "protein_name": "Tigger transposable element-derived protein 3", "gene_name": "TIGD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELSSKKKLHALSLAEKIQVLELLDESKMSQSEVARRFQVSQPQISRICKNKEKLLADWCSGTANRERKRKRESKYSGIDEALLCWYHIARAKAWDVTGPMLLHKAKELADIMGQDFVPSIGWLVRWKRRNNVGFGARHVLAPSFPPEPPPPGLTSQAQLPLSLKDFSPEDVFGCAELPLLYRAVPGSFGACDQVQVLLCANSRGTEKRRVLLGGLQAAPRCFFGIRSEALPASYHPDLGIPWLEWLAQFDRDMGQQGRQVALLLAARVVEELAGLPGLYHVKLLPLAASSTTPPLPSSVVRAFKAHYRHRLLGKLAAIQSERDGTSLAEAGAGITVLDALHVASAAWAKVPPQLIFSSFIQEGLAPGKTPPSSHKTSEMPPVPGGLSLEEFSRFVDLEGEEPRSGVCKEEIGTEDEKGDREGAFEPLPTKADALRALGTLRRWFECNSTSPELFEKFYDCEEEVERLCCL", "length": 471 }, "evidence": [ { "id": "A0A3L7HVW9", "url": "https://omabrowser.org/oma/group/A0A3L7HVW9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TM95-1", "protein_name": "Tigger transposable element-derived protein 3", "gene_name": "Tigd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELNTKKKLHALSLAEKIQVLELLDESKMSQSEVARRFQVSQPQISRICKNKEKLLADWCSGTANHERKRKRESKYSGIDEALLCWYHIARAKAWDVTGPMLLHKAKELADIMGQDFVPSIGWLVRWKRRNNVGFGTRQVLVPLFPPEAPPAVLPSQAQPPLSLKDFSPEDVFGCAEVPLLYRAVPGRVFECDRLQVLLCANSRGTEKRRVFVGGLQAAPRCFFGVSSEALPTSYHPDLAIPWSEWLAQFDQDMGQQGRQVALLLASGVVEEWASLPGLHHVRLLPLSASSTTPSLPGSVILAFKAHYRHRLLSKLAAMQSGKEGTSLAEARASITVLDALHMVAAAWAKVPRQLILSSFVQEGLAPGKTPLSLDKDTEMSPVPSGLSQEEFSHFVDLEDEDPGPRVCKEETGTEDSGREEDGFEPLPTKADALQALCTLRRWLECNSASPELFEKFYDCEVEVEQLCCL", "length": 470 }, "evidence": [ { "id": "A0A3L7HVW9", "url": "https://omabrowser.org/oma/group/A0A3L7HVW9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HVW9", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HVW9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HVW9", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HVW9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 447, "end_pos": 449, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3L7HVW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HVW9" }, { "id": "PRU00320", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00320" } ], "ann_type": "Nucleotide_Binding_Annotation", "uniprotkb_annotation": "H-T-H motif", "eco_id": "ECO_0000256", "start_pos": 31, "end_pos": 51, "start_aa": "Gln", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A3L7HVW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HVW9" }, { "id": "PS51253", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51253" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HTH CENPB-type", "eco_id": "ECO_0000259", "start_pos": 67, "end_pos": 137, "start_aa": "Glu", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A3L7HVW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HVW9" }, { "id": "PS50960", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50960" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HTH psq-type", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 55, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 334, "end_pos": 336 }, { "start_pos": 447, "end_pos": 449 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7HVZ0-1", "uniprot_ac": "A0A3L7HVZ0", "uniprot_id": "A0A3L7HVZ0_CRIGR", "mass": { "chemical_mass": 54651.0, "monoisotopic_mass": 54651.0 }, "refseq": { "ac": "XP_003507201", "name": "pleckstrin homology domain-containing family O member 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507201" }, "gene_names": [ { "name": "Plekho2", "type": "recommended", "evidence": [ { "id": "A0A3L7HVZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HVZ0" } ] }, { "name": "Plekho2", "type": "synonym", "evidence": [ { "id": "XP_003507201", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507201" } ] } ], "protein_names": [ { "name": "Pleckstrin homology domain-containing family O member 2 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A3L7HVZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HVZ0/entry#names_and_taxonomy" } ] }, { "name": "pleckstrin homology domain-containing family O member 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003507201", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507201" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 147 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614337.1) and transcript sequence (IACG01064160.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003507201.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003507201", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507201" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HVZ0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HVZ0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Plekho2", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HVZ0", "locus": {} } ], "crossref": [ { "id": "cd13317", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13317", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100752155", "url": "https://www.ncbi.nlm.nih.gov/gene/100752155", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043448", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043448", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752155", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752155", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3L7HVZ0", "url": "https://www.orthodb.org/?gene=A0A3L7HVZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15871", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15871", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15871:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15871:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003507201", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507201", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HVZ0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HVZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HVZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HVZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEESMKEGSDKPRGARTADKAGWIKKSSGGLLSLWKDRYLLLCQAQLLVYENEDEQKCVETVELGSYEKCQDLRAVLKRKHRFILLRSPGNKVSDIKFQAPSGEEKESWIKALNEGINRGKNKAFDEVKVDKTCALEHVTRNRVRGGQRRRPPTRIHLKEVASAASDGLLRLDLDVPDSGPPVFAPVNDVSETQPQEPPRVLMPPVKPSPVPETCSTDDSMETPAGERGPTPVSASPEAKPESQEDAETPAEGDSDFKRHPNSTWFERLKVSWENPSPEESAALESSQLPKVPSSETPEAAPRESKKPPVPPPKILSEKMKACMGGVDASSLSQSSEAPETTAPGPTQVSVNGMDDSPESAVPSQAMGTPGTAPEGATAPPALPFWDLPSQFHPRSSSLGDLLRDGPQHPKLPKEKLYRAQLEVKVASKQTEQLLNQVLSSEPQPVCAESLLSQAVEQLRQATQVLQEMRDLGELNQETPGLVQKRKELVTLYRRSAP", "length": 499, "header": "tr|A0A3L7HVZ0-1|A0A3L7HVZ0_CRIGR Isoform 1 of Pleckstrin homology domain-containing family O member 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Plekho2 PE=4 SV=1 CANONICAL=A0A3L7HVZ0-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HVZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HVZ0/entry#A0A3L7HVZ0-1", "sequence": { "sequence": "MEEESMKEGSDKPRGARTADKAGWIKKSSGGLLSLWKDRYLLLCQAQLLVYENEDEQKCVETVELGSYEKCQDLRAVLKRKHRFILLRSPGNKVSDIKFQAPSGEEKESWIKALNEGINRGKNKAFDEVKVDKTCALEHVTRNRVRGGQRRRPPTRIHLKEVASAASDGLLRLDLDVPDSGPPVFAPVNDVSETQPQEPPRVLMPPVKPSPVPETCSTDDSMETPAGERGPTPVSASPEAKPESQEDAETPAEGDSDFKRHPNSTWFERLKVSWENPSPEESAALESSQLPKVPSSETPEAAPRESKKPPVPPPKILSEKMKACMGGVDASSLSQSSEAPETTAPGPTQVSVNGMDDSPESAVPSQAMGTPGTAPEGATAPPALPFWDLPSQFHPRSSSLGDLLRDGPQHPKLPKEKLYRAQLEVKVASKQTEQLLNQVLSSEPQPVCAESLLSQAVEQLRQATQVLQEMRDLGELNQETPGLVQKRKELVTLYRRSAP", "length": 499, "header": "tr|A0A3L7HVZ0-1|A0A3L7HVZ0_CRIGR Isoform 1 of Pleckstrin homology domain-containing family O member 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Plekho2 PE=4 SV=1 CANONICAL=A0A3L7HVZ0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 232, "start_aa": "Thr", "end_pos": 232, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr232", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 348, "start_aa": "Thr", "end_pos": 348, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr348", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HVZ0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HVZ0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HVZ0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HVZ0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752155", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752155", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "macrophage apoptotic process", "id": "GO:0071888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071888", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HVZ0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HVZ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 263, "end_pos": 265, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3L7HVZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HVZ0" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 18, "end_pos": 119, "start_aa": "Thr", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 232, 348 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 263, "end_pos": 265 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7HW16-1", "uniprot_ac": "A0A3L7HW16", "uniprot_id": "A0A3L7HW16_CRIGR", "mass": { "chemical_mass": 51416.0, "monoisotopic_mass": 51416.0 }, "refseq": { "ac": "XP_027264438", "name": "transmembrane protein 151A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264438" }, "gene_names": [ { "name": "Tmem151a", "type": "recommended", "evidence": [ { "id": "A0A3L7HW16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HW16" } ] }, { "name": "Tmem151a", "type": "synonym", "evidence": [ { "id": "XP_027264438", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264438" } ] } ], "protein_names": [ { "name": "Transmembrane protein 151A", "type": "synonym", "evidence": [ { "id": "A0A3L7HW16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HW16/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 151A", "type": "synonym", "evidence": [ { "id": "XP_027264438", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264438" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027264438", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264438" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HW16", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HW16" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tmem151a", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HW16", "locus": {} } ], "crossref": [ { "id": "100763330", "url": "https://www.ncbi.nlm.nih.gov/gene/100763330", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026767", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026767", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763330", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763330", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3L7HW16", "url": "https://www.orthodb.org/?gene=A0A3L7HW16", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31893", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31893", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31893:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31893:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14857", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14857", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027264438", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264438", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HW16", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HW16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HW16-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HW16-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPEGEGGDCGEVPAALIPDSEPLREEQRPLKQSLGGSLCRESHWKCLLLTLLIHACGAVVAWCRLATVPRLVLGPEAALARGAGGPPPTYPASPCSDGYLYIPLAFVSLLYLLYLAECWHCHVRSCQAPRTDANTVLALIRRLQQAPPCVWWKATSYHYVRRTRQITRYRNGDAYTTTQVYHERADSRTARGEFDYSAHGVRDVSKELVGLADHAATRLRFTKCFSFGSAEAEASYLTQRARFFSANEGLDDYLEAREGMHLKDVDFRESLMVFADPRSPPWYARAWVFWLVSAATLSWPLRVVAAYGTAHVHYQVEKLFGASSPPPGAVPSGPPLSRVATVDFTELEWHICSNRQLVPSYSEAVVMGASSGAYLRGCQRCRRSVSSNSLPPARPSGPRLPFSRSRLSLGAGGRATPGVFRSLSGGPLGRRGEDTEPLESPPCYEDALYFPVLIVHGDSGCRGDGQGAL", "length": 469, "header": "tr|A0A3L7HW16-1|A0A3L7HW16_CRIGR Isoform 1 of Transmembrane protein 151A OS=Cricetulus griseus OX=10029 GN=Tmem151a PE=3 SV=1 CANONICAL=A0A3L7HW16-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HW16-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HW16/entry#A0A3L7HW16-1", "sequence": { "sequence": "MPEGEGGDCGEVPAALIPDSEPLREEQRPLKQSLGGSLCRESHWKCLLLTLLIHACGAVVAWCRLATVPRLVLGPEAALARGAGGPPPTYPASPCSDGYLYIPLAFVSLLYLLYLAECWHCHVRSCQAPRTDANTVLALIRRLQQAPPCVWWKATSYHYVRRTRQITRYRNGDAYTTTQVYHERADSRTARGEFDYSAHGVRDVSKELVGLADHAATRLRFTKCFSFGSAEAEASYLTQRARFFSANEGLDDYLEAREGMHLKDVDFRESLMVFADPRSPPWYARAWVFWLVSAATLSWPLRVVAAYGTAHVHYQVEKLFGASSPPPGAVPSGPPLSRVATVDFTELEWHICSNRQLVPSYSEAVVMGASSGAYLRGCQRCRRSVSSNSLPPARPSGPRLPFSRSRLSLGAGGRATPGVFRSLSGGPLGRRGEDTEPLESPPCYEDALYFPVLIVHGDSGCRGDGQGAL", "length": 469, "header": "tr|A0A3L7HW16-1|A0A3L7HW16_CRIGR Isoform 1 of Transmembrane protein 151A OS=Cricetulus griseus OX=10029 GN=Tmem151a PE=3 SV=1 CANONICAL=A0A3L7HW16-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 416, "start_aa": "Thr", "end_pos": 416, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr416", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Classification" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018067", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018067", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774343", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774343", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "cge:103160255", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103160255", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A9J7KFP4", "url": "https://www.orthodb.org/?gene=A0A9J7KFP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11871", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11871", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_027264880", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027264880", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HWN8", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HWN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HWN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HWN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KFP4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KFP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KFP4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HWN8", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HWN8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774343", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774343", "resource": "KEGG Pathway" }, { "id": "cge:103160255", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103160255", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "protein phosphatase type 2A complex", "id": "GO:0000159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000159", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HWN8", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HWN8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein phosphatase regulator activity", "id": "GO:0019888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019888", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HWN8", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HWN8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 357, "end_pos": 359, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 357, "end_pos": 359 }, { "start_pos": 43, "end_pos": 45 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 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}, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7HWR0-1", "uniprot_ac": "A0A3L7HWR0", "uniprot_id": "A0A3L7HWR0_CRIGR", "mass": { "chemical_mass": 11631.0, "monoisotopic_mass": 11631.0 }, "refseq": { "ac": "XP_035297499", "name": "protein FAM24A-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297499" }, "gene_names": [ { "name": "LOC103162379", "type": "recommended", "evidence": [ { "id": "A0A3L7HWR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HWR0" } ] }, { "name": "LOC103162379", "type": "synonym", "evidence": [ { "id": "XP_035297499", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297499" } ] } ], "protein_names": [ { "name": "Protein FAM24A-like", "type": "synonym", "evidence": [ { "id": "A0A3L7HWR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HWR0/entry#names_and_taxonomy" } ] }, { "name": "protein FAM24A-like", "type": "synonym", "evidence": [ { "id": "XP_035297499", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297499" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 8% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035297499", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297499" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HWR0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HWR0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC103162379", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HWR0", "locus": {} } ], "crossref": [ { "id": "103162379", "url": "https://www.ncbi.nlm.nih.gov/gene/103162379", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:103162379", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103162379", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3L7HWR0", "url": "https://www.orthodb.org/?gene=A0A3L7HWR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35860", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35860", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35860:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35860:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15193", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15193", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035297499", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035297499", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HWR0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HWR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HWR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HWR0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRFFDVRAILMIIIGCGILLAMFLLIGVVLCLYLKITKALNYSCRTAKDSVATVSCIGPCKITQDKIVRAKPIVESCRNIQCCDACSVYTDVGSLPPCFCNVSEGL", "length": 107, "header": "tr|A0A3L7HWR0-1|A0A3L7HWR0_CRIGR Isoform 1 of Protein FAM24A-like OS=Cricetulus griseus OX=10029 GN=LOC103162379 PE=3 SV=1 CANONICAL=A0A3L7HWR0-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HWR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HWR0/entry#A0A3L7HWR0-1", "sequence": { "sequence": "MSRFFDVRAILMIIIGCGILLAMFLLIGVVLCLYLKITKALNYSCRTAKDSVATVSCIGPCKITQDKIVRAKPIVESCRNIQCCDACSVYTDVGSLPPCFCNVSEGL", "length": 107, "header": "tr|A0A3L7HWR0-1|A0A3L7HWR0_CRIGR Isoform 1 of Protein FAM24A-like OS=Cricetulus griseus OX=10029 GN=LOC103162379 PE=3 SV=1 CANONICAL=A0A3L7HWR0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HWR0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HWR0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HWR0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HWR0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:103162379", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103162379", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HWR0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HWR0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HY44", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HY44" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752772", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752772", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TQQ5-1", "protein_name": "ATP synthase membrane subunit k", "gene_name": "ATP5MK", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGPETDAQFQFTGIKKYFNSYTLTGRMNCVLATYGGIALLVLYFKLRSKKTPAVKAT", "length": 58 }, "evidence": [ { "id": "A0A3L7HY44", "url": "https://omabrowser.org/oma/group/A0A3L7HY44/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "H0WES8-1", "protein_name": "ATP synthase membrane subunit 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"type": "recommended", "evidence": [ { "id": "A0A3L7HYL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HYL3/entry#names_and_taxonomy" } ] }, { "name": "Basophilic leukemia-expressed protein Bles03", "type": "synonym", "evidence": [ { "id": "A0A3L7HYL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HYL3/entry#names_and_taxonomy" } ] }, { "name": "UPF0696 protein C11orf68 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003509489", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509489" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 209 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614712.1) and transcript sequence (IACG01092852.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003509489.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003509489", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509489" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HYL3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HYL3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "CUNH11orf68", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HYL3", "locus": {} } ], "crossref": [ { "id": "100766243", "url": "https://www.ncbi.nlm.nih.gov/gene/100766243", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR015034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023398", "url": 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"database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HYL3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HYL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HYL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HYL3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FR10", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FR10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FR10-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FR10-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAAAAVAGAGRGAGGGADPGQERSRARSWVGAERSEGRRMEPNEELEEEDSPGGREDGFTAEHLAAEAMAADMDPWLVFDARTTPASELDAWLAKYPPSQVTRYGDPGSPNSEPVGWIAAYGQGYTPNSGDVQGLQAAWEALQTSGRPITPGTLRQLAITHHVLSGKWLIHLAPGFKLDHAWAGIARAVVEGRLQVAKVSPRAKEGGRQVICVYTDDFTDRLGVLEADSAIRAAGIKCLLTYKPDVYTYLGIYRANRWHLCPTLYESRFQLGGNARGSRVLDRANNVELT", "length": 292, "header": "tr|A0A3L7HYL3-1|A0A3L7HYL3_CRIGR Isoform 1 of UPF0696 protein C11orf68 homolog OS=Cricetulus griseus OX=10029 GN=CUNH11orf68 PE=3 SV=1 CANONICAL=A0A3L7HYL3-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HYL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HYL3/entry#A0A3L7HYL3-1", "sequence": { "sequence": "MAAAAAAVAGAGRGAGGGADPGQERSRARSWVGAERSEGRRMEPNEELEEEDSPGGREDGFTAEHLAAEAMAADMDPWLVFDARTTPASELDAWLAKYPPSQVTRYGDPGSPNSEPVGWIAAYGQGYTPNSGDVQGLQAAWEALQTSGRPITPGTLRQLAITHHVLSGKWLIHLAPGFKLDHAWAGIARAVVEGRLQVAKVSPRAKEGGRQVICVYTDDFTDRLGVLEADSAIRAAGIKCLLTYKPDVYTYLGIYRANRWHLCPTLYESRFQLGGNARGSRVLDRANNVELT", "length": 292, "header": "tr|A0A3L7HYL3-1|A0A3L7HYL3_CRIGR Isoform 1 of UPF0696 protein C11orf68 homolog OS=Cricetulus griseus OX=10029 GN=CUNH11orf68 PE=3 SV=1 CANONICAL=A0A3L7HYL3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FR10-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HYL3/entry#A0A9J7FR10-1", "sequence": { "sequence": "MAAAAAAVAGAGRGAGGGADPGQERSRARSWVGAERSEGRSSLTTGWNQMRSWKRRTLPVAVRMASLLSTWLQRPWQPTWTPGWYLMPVLHLPQSWMPGWPSTHHLKLLAMGTRVHPTLNLWVGLQPMGRVTPPTQGMFKGCRQPGRLCRPVGGPSRQVPCASWLSPTMCSLASG", "length": 175, "header": "tr|A0A9J7FR10-1|A0A9J7FR10_CRIGR Computationally mapped isoform of UPF0696 protein C11orf68 homolog isoform X3 OS=Cricetulus griseus OX=10029 GN=CUNH11orf68 PE=4 SV=1 CANONICAL=A0A3L7HYL3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 152, "start_aa": "Thr", "end_pos": 152, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr152", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" 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Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613865.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 27, 2016 this sequence version replaced XP_003501959.2. 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interacting RNase isoform X1 OS=Cricetulus griseus OX=10029 GN=Trir PE=4 SV=1 CANONICAL=A0A3L7HZL9-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HZL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HZL9/entry#A0A3L7HZL9-1", "sequence": { "sequence": "MAARGRRAEPPSREVPGPAGGGRSRWAESGPGTSPESGDDEVSGSSPVSGGVNLFANDGSFLELFKRKMEEEQRQRQEEPPPGPQRPDPSASAAAGPGNPKRKGGPGPTLSFVGKRRGGNKLALKTGIVAKKQKTEDEVLTSKGDAWAKYMAEVKKYKAHQCGDDDKTRPLVK", "length": 173, "header": "tr|A0A3L7HZL9-1|A0A3L7HZL9_CRIGR Isoform 1 of Telomerase RNA component interacting RNase isoform X1 OS=Cricetulus griseus OX=10029 GN=Trir PE=4 SV=1 CANONICAL=A0A3L7HZL9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FKB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HZL9/entry#A0A9J7FKB4-1", "sequence": { "sequence": "MAARGRRAEPPSREVPGPAGGGRSRWAESGPGTSPESGDDEVSGSSPVSGGVNLFANDGSFLELFKRKMEEEQRQRQEEPPPGPQRPDPSASAAAGPGNPKRKGGPGPTLSFVGWLEELGEASIGRCSGPQHRQGRARLL", "length": 140, "header": "tr|A0A9J7FKB4-1|A0A9J7FKB4_CRIGR Computationally mapped isoform of Telomerase RNA component interacting RNase isoform X2 OS=Cricetulus griseus OX=10029 GN=Trir PE=4 SV=1 CANONICAL=A0A3L7HZL9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FN87-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HZL9/entry#A0A9J7FN87-1", "sequence": { "sequence": "MAARGRRAEPPSREVPGPAGGGRSRWAESGPGTSPESGDDEVSGSSPVSGGVNLFANDGSFLELFKRKMEEEQRQRQEEPPPGPQRPDPSASAAAGPGNPKRKGGGQAQRREQTSPQDGNSSQEAEDGG", "length": 129, "header": "tr|A0A9J7FN87-1|A0A9J7FN87_CRIGR Computationally mapped isoform of Telomerase RNA component interacting RNase isoform X3 OS=Cricetulus griseus OX=10029 GN=Trir PE=4 SV=1 CANONICAL=A0A3L7HZL9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, 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"glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZGR7-1", "protein_name": "Telomerase RNA component interacting RNase", "gene_name": "Trir", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAARGRRAEPPGREAPGPAGSGRSRWAESGPGTSPESGDDEVSGSSPVSSGVNLFANDGSFLELFKRKMEEEQRQRQEEPPPGPQRPDQPASAAAGPGNQKRKGGPGPTFSFVGKRRGGNKLALKTGIVAKKQKTEDEVLTSKGDAWAKYMAEVKKYKAHQCGDDDKTRPLVK", "length": 173 }, "evidence": [ { "id": "A0A3L7HZL9", "url": "https://omabrowser.org/oma/group/A0A3L7HZL9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MHW3-1", "protein_name": "Telomerase RNA component interacting RNase", "gene_name": "TRIR", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": 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Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027260089", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260089" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I288", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I288" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "CUNH8orf82", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I288", "locus": {} } ], "crossref": [ { "id": "103159751", "url": "https://www.ncbi.nlm.nih.gov/gene/103159751", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:103159751", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103159751", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3L7I288", "url": "https://www.orthodb.org/?gene=A0A3L7I288", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31449", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31449", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31449:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31449:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14956", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14956", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027260089", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260089", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7I288", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I288", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7I288-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I288-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWPPCGSLRNLALLLARSQRARACSGDERVSYTQGQSPEPRTREYFYYVDHQGQLFLDDSKMKNFITCFKDRQFLVTFFSRLRPNHSGRYEASFPFLSLCGRERNFLRCEDRPLVFTHLLATDSESPRLSYCGGGEALAVPFEPARLLPLAANGRLYHPAPASAGGVGLVRSALAFELSACFEYGPGSPTVPSHVHWQGRRVALTMDLAPLLPAAPPP", "length": 218, "header": "tr|A0A3L7I288-1|A0A3L7I288_CRIGR Isoform 1 of UPF0598 protein C8orf82 homolog isoform X2 OS=Cricetulus griseus OX=10029 GN=CUNH8orf82 PE=3 SV=1 CANONICAL=A0A3L7I288-1" }, "isoforms": [ { "isoform_ac": "A0A3L7I288-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I288/entry#A0A3L7I288-1", "sequence": { "sequence": "MWPPCGSLRNLALLLARSQRARACSGDERVSYTQGQSPEPRTREYFYYVDHQGQLFLDDSKMKNFITCFKDRQFLVTFFSRLRPNHSGRYEASFPFLSLCGRERNFLRCEDRPLVFTHLLATDSESPRLSYCGGGEALAVPFEPARLLPLAANGRLYHPAPASAGGVGLVRSALAFELSACFEYGPGSPTVPSHVHWQGRRVALTMDLAPLLPAAPPP", "length": 218, "header": "tr|A0A3L7I288-1|A0A3L7I288_CRIGR Isoform 1 of UPF0598 protein C8orf82 homolog isoform X2 OS=Cricetulus griseus OX=10029 GN=CUNH8orf82 PE=3 SV=1 CANONICAL=A0A3L7I288-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"name": "COMM domain-containing protein 3", "type": "recommended", "evidence": [ { "id": "A0A3L7I2B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2B0/entry#names_and_taxonomy" } ] }, { "name": "COMM domain-containing protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007638365", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638365" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 183 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613736.1) and transcript sequence (JI876367.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007638365", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638365" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I2B0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2B0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100754672", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2B0", "locus": {} } ], "crossref": [ { "id": "cd04751", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04751", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100754672", "url": "https://www.ncbi.nlm.nih.gov/gene/100754672", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR017920", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017920", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037355", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037355", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7I2B0", "url": "https://www.orthodb.org/?gene=A0A3L7I2B0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31159", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31159", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31159:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31159:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07258", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07258", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21672", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21672", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007638365", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638365", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7I2B0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2B0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7I2B0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2B0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELSEYVQRGFQRLADPGSFDSNAFALLLRAAFQSLLDARADEAALDHPGLKHIDPVVLKHCHAAAATYILEAGKHRVDRSTLSTYLEDCKFDQDRIEIFCTEYQNNKNSLEILLGSIGRSLPHITDVSWRLEYQIKTNQLHKMYQPGYLVTLNVENSDSQSYPEISFSCNMEQLQDLVGKLKDASKSLERATQL", "length": 195, "header": "tr|A0A3L7I2B0-1|A0A3L7I2B0_CRIGR Isoform 1 of COMM domain-containing protein 3 OS=Cricetulus griseus OX=10029 GN=LOC100754672 PE=3 SV=1 CANONICAL=A0A3L7I2B0-1" }, "isoforms": [ { "isoform_ac": "A0A3L7I2B0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2B0/entry#A0A3L7I2B0-1", "sequence": { "sequence": "MELSEYVQRGFQRLADPGSFDSNAFALLLRAAFQSLLDARADEAALDHPGLKHIDPVVLKHCHAAAATYILEAGKHRVDRSTLSTYLEDCKFDQDRIEIFCTEYQNNKNSLEILLGSIGRSLPHITDVSWRLEYQIKTNQLHKMYQPGYLVTLNVENSDSQSYPEISFSCNMEQLQDLVGKLKDASKSLERATQL", "length": 195, "header": "tr|A0A3L7I2B0-1|A0A3L7I2B0_CRIGR Isoform 1 of COMM domain-containing protein 3 OS=Cricetulus griseus OX=10029 GN=LOC100754672 PE=3 SV=1 CANONICAL=A0A3L7I2B0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614855.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003510324", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510324" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I2P0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2P0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "C2H22orf23", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2P0", "locus": {} } ], "crossref": [ { "id": "100753660", "url": "https://www.ncbi.nlm.nih.gov/gene/100753660", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753660", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753660", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MMAYGKD", "url": "https://omabrowser.org/oma/group/MMAYGKD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7I2P0", "url": "https://www.orthodb.org/?gene=A0A3L7I2P0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MU22", "url": "https://www.orthodb.org/?gene=A0A8C2MU22", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28348", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28348", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28348:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28348:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05250", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05250", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003510324", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510324", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7I2P0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2P0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7I2P0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2P0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MU22", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MU22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MU22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MU22-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GRY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GRY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GRY7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GVB7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GVB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GVB7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASQERVDAVSNGTGFQRCGKQLAYTPGTCELLRVMMKESRLTNFQQRHIMDTVKRGAPLPLQCDPTSSHRGSPSKKPATATYLPPILATHSHLRPASMCQANGAYSREQFKPQATRDLEKEKRRLQNIFANGKDIEERKRAPHGLQEDPAPELDRFEELVKEIQDRKEFLAAMEALGQGKQYRGMILAEISQKLQEMEEIDRSRSEKLRKALATT", "length": 216, "header": "tr|A0A3L7I2P0-1|A0A3L7I2P0_CRIGR Isoform 1 of UPF0193 protein EVG1 isoform X2 OS=Cricetulus griseus OX=10029 GN=C2H22orf23 PE=4 SV=1 CANONICAL=A0A3L7I2P0-1" }, "isoforms": [ { "isoform_ac": "A0A3L7I2P0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2P0/entry#A0A3L7I2P0-1", "sequence": { "sequence": "MASQERVDAVSNGTGFQRCGKQLAYTPGTCELLRVMMKESRLTNFQQRHIMDTVKRGAPLPLQCDPTSSHRGSPSKKPATATYLPPILATHSHLRPASMCQANGAYSREQFKPQATRDLEKEKRRLQNIFANGKDIEERKRAPHGLQEDPAPELDRFEELVKEIQDRKEFLAAMEALGQGKQYRGMILAEISQKLQEMEEIDRSRSEKLRKALATT", "length": 216, "header": "tr|A0A3L7I2P0-1|A0A3L7I2P0_CRIGR Isoform 1 of UPF0193 protein EVG1 isoform X2 OS=Cricetulus griseus OX=10029 GN=C2H22orf23 PE=4 SV=1 CANONICAL=A0A3L7I2P0-1" }, "locus": {} }, { "isoform_ac": "A0A8C2MU22-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2P0/entry#A0A8C2MU22-1", "sequence": { "sequence": "MASQERVDAVSNGTGFQRCGKQLAYTPGTCELLRVMMKESRLTNFQQRHIMDTVKRDLEKEKRRLQNIFANGKDIEERKRAPHGLQEDPAPELDRFEELVKEIQDRKEFLAAMEALGQGKQYRGMILAEISQKLQEMEEIDRSRSEKLRKALATT", "length": 155, "header": "tr|A0A8C2MU22-1|A0A8C2MU22_CRIGR Computationally mapped isoform of UPF0193 protein EVG1 isoform X5 OS=Cricetulus griseus OX=10029 GN=C2H22orf23 PE=4 SV=1 CANONICAL=A0A3L7I2P0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GRY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2P0/entry#A0A9J7GRY7-1", "sequence": { "sequence": "MMKESRLTNFQQRHIMDTVKRDLEKEKRRLQNIFANGKDIEERKRAPHGLQEDPAPELDRFEELVKEIQDRKEFLAAMEALGQGKQYRGMILAEISQKLQEMEEIDRSRSEKLRKALATT", "length": 120, "header": "tr|A0A9J7GRY7-1|A0A9J7GRY7_CRIGR Computationally mapped isoform of UPF0193 protein EVG1 isoform X6 OS=Cricetulus griseus OX=10029 GN=C2H22orf23 PE=4 SV=1 CANONICAL=A0A3L7I2P0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GVB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2P0/entry#A0A9J7GVB7-1", "sequence": { "sequence": "MMKESRLTNFQQRHIMDTVKRGAPLPLQCDPTSSHRGSPSKKPATATYLPPILATHSHLRPASMCQANGAYSREQFKPQATRDLEKEKRRLQNIFANGKDIEERKRAPHGLQEDPAPELDRFEELVKEIQDRKEFLAAMEALGQGKQYRGMILAEISQKLQEMEEIDRSRSEKLRKALATT", "length": 181, "header": "tr|A0A9J7GVB7-1|A0A9J7GVB7_CRIGR Computationally mapped isoform of UPF0193 protein EVG1 isoform X3 OS=Cricetulus griseus OX=10029 GN=C2H22orf23 PE=4 SV=1 CANONICAL=A0A3L7I2P0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I2P0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2P0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I2P0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2P0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753660", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753660", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QM26-1", "protein_name": "Chromosome 5 C22orf23 homolog", "gene_name": "C5H22orf23", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASQERVETVTKGTGFWRCPKPAAYTPRTCELLRAMMKESKLTNFQQRHIMDTMKRGDALPLHCSPTSSQRVLPARQPASAIYLPPILAARSHLRPASLCQANGAYSREQFRPQATRDLEKEKRRLQNIFATGKEPEERKRKPPPVQQEAPAPELDRFEELVKEIQERKAFLADMEALGQGRRYRGVILTEISQKLQEMEDLDRKRSEELRKALATP", "length": 217 }, "evidence": [ { "id": "A0A3L7I2P0", "url": "https://omabrowser.org/oma/group/A0A3L7I2P0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E7F0P7-1", "protein_name": "UPF0193 protein EVG1", "gene_name": "si:dkey-43k4.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMASGSKYKESGIPQYRTDTRQLIKLMMQESRLTDFQQRQINNKLKNGGALPITFYSSPLEPNTPSETRVTRVGTLVGQQQKRSAERCRAGDNYKREQFLPSAARDLEKEKRKLQNLLSTGQKDAGPTHSQRESTERREQPVDRFQEVLDEIEDRRQFLEEMMSLGKGHQYQQLINTEISQKICELEEIDKKRSEELRTPQLTGKEEQ", "length": 208 }, "evidence": [ { "id": "A0A3L7I2P0", "url": "https://omabrowser.org/oma/group/A0A3L7I2P0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1N6I1-1", "protein_name": "Chromosome 5 C22orf23 homolog", "gene_name": "C5H22orf23", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASQERVETVTKGTGFWRCPKPTTYTPGTCELLRVMMKESKLTNFQQRHITDTMKRGDTLPLQCNPTSSQRVLPSKQPSSAIYLPPILAARSHLRPAWRCQANGAYSREQFKPQATRDLEMEKRRLQNIFATGKEPEERKRKPHPLRQEDPAPKLDRFEELVKEIQERKEFLADMEALGQGRQYRGIILTEISQKLQEMEDIDHKRSEELRKALATT", "length": 217 }, "evidence": [ { "id": "A0A3L7I2P0", "url": "https://omabrowser.org/oma/group/A0A3L7I2P0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F7FLU1-1", "protein_name": "Similar to human chromosome 22 open reading frame 23", "gene_name": "C7h22orf23", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNPPMASQERVDAVANGTGFHRCRKQAAYTPGTCELLRVMMKESKLTNFQQRHIMDTMKRGAPLPLQCNPTSSQRGSPSKKSAAAIYLPPILATHTHLRPASLCQANGAYSREQFKPQATRDLEKEKRRLQNIFATGKDMEERKKVPHVQQEDPAPELDRFDELVKEIQDRKEFLAAMEALGQGKQYRGIILAEISQKLREMEDIDRRRSKELRKALTTT", "length": 220 }, "evidence": [ { "id": "A0A3L7I2P0", "url": "https://omabrowser.org/oma/group/A0A3L7I2P0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BZE7-1", "protein_name": "UPF0193 protein EVG1", "gene_name": "C22orf23", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASQKQMEVVTKGTGFRRRPKTITYTPGTCELLRVMMKESKLTNIQQRHIMDIMKRGDALPLQCSPTSSQRVLPSKQIASPIYLPPILAARPHLRPANMCQANGAYSREQFKPQATRDLEKEKQRLQNIFATGKDMEERKRKAPPARQKAPAPELDRFEELVKEIQERKEFLADMEALGQGKQYRGIILAEISQKLREMEDIDHRRSEELRKGLATT", "length": 217 }, "evidence": [ { "id": "A0A3L7I2P0", "url": "https://omabrowser.org/oma/group/A0A3L7I2P0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D9S1-1", "protein_name": "UPF0193 protein EVG1 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQERVDSVTKGTGFRRCRKQAGYTPGTCELLRVMMKESKLTNFQQRHIMDTMKRGAPLPLQCNPTSSLRGSPSKKAASAIYLPPILATHSHLRPASLCQANGAYSREQFKPQATRDLEKEKRRLQNIFATGKDKEERKKVPHVRQEDPAPELDRFDELVKEIQDRKEFLAAMEALGQGRQYRSIILAEISQKLREMEDIDRRRSKELRKALATT", "length": 216 }, "evidence": [ { "id": "A0A3L7I2P0", "url": "https://omabrowser.org/oma/group/A0A3L7I2P0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VSS7-1", "protein_name": "UPF0193 protein EVG1 homolog", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSRHRFNNVQIKALPGGLMAHHEPDADGGQPGSQKLPMWPSERIPPGGAGAFHSAKVQYSKETADLIRLLVKESKMSMLVRKQIDESLRNGEPLPLPEPPRPNTNNDPDKETLAILDRARNAKRKNLRQIEASGAYKQSYYRPPADNRMHGEKAKSQLQFTMAGTHLPDPAIKPRRRPREEQLVTEEDLINELLDQINERAEWLTEMESMGQGKKYRPEIRDQIAERLRRIQALESKMKMKSNGGFRFVD", "length": 250 }, "evidence": [ { "id": "A0A3L7I2P0", "url": "https://omabrowser.org/oma/group/A0A3L7I2P0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 12, "end_pos": 14, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 12, "end_pos": 14 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7I2W2-1", "uniprot_ac": "A0A3L7I2W2", "uniprot_id": "A0A3L7I2W2_CRIGR", "mass": { "chemical_mass": 43056.0, "monoisotopic_mass": 43056.0 }, "refseq": { "ac": "XP_027260076", "name": "protein HGH1 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260076" }, "gene_names": [ { "name": "Hgh1", "type": "recommended", "evidence": [ { "id": "A0A3L7I2W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2W2" } ] }, { "name": "Hgh1", "type": "synonym", "evidence": [ { "id": "XP_027260076", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260076" } ] } ], "protein_names": [ { "name": "Co-chaperone protein HGH1 homolog", "type": "recommended", "evidence": [ { "id": "A0A3L7I2W2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2W2/entry#names_and_taxonomy" } ] }, { "name": "protein HGH1 homolog", "type": "synonym", "evidence": [ { "id": "XP_027260076", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260076" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027260076", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260076" } ] }, { "annotation": "Co-chaperone involved in the folding of nascent eukaryotic elongation factor eEF2, an essential component of the translation machinery. Recognizes a non-native conformation in the central domain of eEF2 and recruits the chaperonin-containing T-complex (TRiC) to the C-terminal region of the nascent polypeptide, preventing unproductive interactions and promoting efficient folding of the N-terminal GTPase domain. 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7I2Y8-1", "uniprot_ac": "A0A3L7I2Y8", "uniprot_id": "A0A3L7I2Y8_CRIGR", "mass": { "chemical_mass": 45693.0, "monoisotopic_mass": 45693.0 }, "refseq": { "ac": "XP_027258862", "name": "actin-like protein 7B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258862" }, "gene_names": [ { "name": "Actl7b", "type": "recommended", "evidence": [ { "id": "A0A3L7I2Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2Y8" } ] }, { "name": "Actl7b", "type": "synonym", "evidence": [ { "id": "XP_027258862", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258862" } ] } ], "protein_names": [ { "name": "Actin-like protein 7B", "type": "synonym", "evidence": [ { "id": "A0A3L7I2Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2Y8/entry#names_and_taxonomy" } ] }, { "name": "actin-like protein 7B", "type": "synonym", "evidence": [ { "id": "XP_027258862", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258862" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027258862", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258862" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I2Y8", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2Y8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Actl7b", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2Y8", "locus": {} } ], "crossref": [ { "id": "cd10214", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10214", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100767172", "url": "https://www.ncbi.nlm.nih.gov/gene/100767172", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767172", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767172", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3L7I2Y8", "url": "https://www.orthodb.org/?gene=A0A3L7I2Y8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11937", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11937", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00022", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00022", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027258862", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258862", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7I2Y8", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2Y8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7I2Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2Y8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATKNSPSPKPMGTAQGDPGEAGTLPASEVGIRDTGSTQLKTKPKKIRKIKALVIDLGSQYCKCGYAGEQRPTYFISSTVGKRNAELAADAGDTFKETYVGHELLNMEASLKLVNPLKHGVVVDWDCIQNIWEYIFHTAMKILPEEHAVLVSDPPLSPSSNREKYAELMFETFNIPAMHVTSQALLSIYSYGKTSGLVVESGHGVSHVVPISEGDLLPGLPCRADYAGCDLTNYLMQLLNESGHKFTDDHLHIIEHIKKKCCYAALLPEEEMNLGLEELRVDYELPDGKVITIGQERFRCSEMLFKPSLVGCTQPGLPELTADCLNRCQGTGFKEEMAANVLLCGGCTMLDGFPERFQRELSLLCPGDSPTVAAASERKTSVWTGGSILASLQAFQQLWVSKEEFEERGCAAIYSKC", "length": 417, "header": "tr|A0A3L7I2Y8-1|A0A3L7I2Y8_CRIGR Isoform 1 of Actin-like protein 7B OS=Cricetulus griseus OX=10029 GN=Actl7b PE=3 SV=1 CANONICAL=A0A3L7I2Y8-1" }, "isoforms": [ { "isoform_ac": "A0A3L7I2Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I2Y8/entry#A0A3L7I2Y8-1", "sequence": { "sequence": "MATKNSPSPKPMGTAQGDPGEAGTLPASEVGIRDTGSTQLKTKPKKIRKIKALVIDLGSQYCKCGYAGEQRPTYFISSTVGKRNAELAADAGDTFKETYVGHELLNMEASLKLVNPLKHGVVVDWDCIQNIWEYIFHTAMKILPEEHAVLVSDPPLSPSSNREKYAELMFETFNIPAMHVTSQALLSIYSYGKTSGLVVESGHGVSHVVPISEGDLLPGLPCRADYAGCDLTNYLMQLLNESGHKFTDDHLHIIEHIKKKCCYAALLPEEEMNLGLEELRVDYELPDGKVITIGQERFRCSEMLFKPSLVGCTQPGLPELTADCLNRCQGTGFKEEMAANVLLCGGCTMLDGFPERFQRELSLLCPGDSPTVAAASERKTSVWTGGSILASLQAFQQLWVSKEEFEERGCAAIYSKC", "length": 417, "header": "tr|A0A3L7I2Y8-1|A0A3L7I2Y8_CRIGR Isoform 1 of Actin-like protein 7B OS=Cricetulus griseus OX=10029 GN=Actl7b PE=3 SV=1 CANONICAL=A0A3L7I2Y8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NW_003614215.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003506187", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506187" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I311", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I311" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tex10", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I311", "locus": {} } ], "crossref": [ { "id": "100775062", "url": "https://www.ncbi.nlm.nih.gov/gene/100775062", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021133", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024679", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024679", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057949", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057949", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100775062", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100775062", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WKLHANN", "url": "https://omabrowser.org/oma/group/WKLHANN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7I311", "url": "https://www.orthodb.org/?gene=A0A3L7I311", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FKI4", "url": "https://www.orthodb.org/?gene=A0A9J7FKI4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16056", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16056", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16056:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16056:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12333", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12333", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25781", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25781", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003506187", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506187", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7I311", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I311", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7I311-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I311-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FFK8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FFK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FFK8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FKI4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FKI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FKI4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTKKRKRQDDFQKVKLKVGKKKPKLENATATNFKTKAIHLPEQLKEDRTLPTNNRKLNIKDLLSQMHHYNAGVKQSALLGLKDLLSQYPFIIDAHLSNILSEVTAVFTDRDANVRLAAVQLLQFLAPKIRTEQISPFFPLVSAHLSSAMTHITEGIQEDSLKVLDVLLEHYPALITGRSSILLKNFVELISHQQLSKGLINRDRSQSWILSVNPNRRVTSQQWRLKVLARLSKFLQALADGSSRLRESEGLQEQKETPHATSNSIFINWKDHASDQQQIQVYENGGSQPNVSSQFRLRYLGAQGAVDEDLSSPENLKGFIEIIIPLLIECWIEALPPQLAAAIGNGIEREPLQVMQQVLNVISLLWKLSKQQDETHTLESWLRKNYLTDFKHHFMSHFPYALKEITKQRKKETNKSIKHCTVLSNNVDHLLLNLTLSDIMVSLANASTLQNDSSWIETIRKFVTETLKGGARLNSKQLNRLLGVSWRLIQMQPNREATEILIKAVYTLYQQRGLLLPVRTLLIKFFSKIYQKEELRSYRLRYRSRVLSRWLAGLPLQLSHLGSRNPELSTQLIDIIHTAAAQANKDLLKSLQAAALRIYDPQEGAVVVLPAESQQRLVQLLYFLPTLPADLLSRLSRCCIMGRLGSSLAATLIGILYMRSSFSGWNHSINDYLMTDVDYLSFLFSTLTGFSKEELAWLQNLRGVPHVIQTSLSPVLLYLTDLDQFLHHWDITEAVCHSLLVIPARSQSFDIMQSAISKHLVGLTVIPDSTAGCIFGVMCKLLDHTCVVSESLLPFLASCCYSLLYFLLTLEKGEAEHLKKRDKLWGVCVSILALLPRVLRLMLQSLRVSRASPEELPVVGQLLRLLLQHVPLRTHMLTNAILVQQIIKNITTLKSGSVQEQWLTDLHYCFSVYISGHPQGPSILNALY", "length": 928, "header": "tr|A0A3L7I311-1|A0A3L7I311_CRIGR Isoform 1 of Testis-expressed protein 10 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tex10 PE=3 SV=1 CANONICAL=A0A3L7I311-1" }, "isoforms": [ { "isoform_ac": "A0A3L7I311-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I311/entry#A0A3L7I311-1", "sequence": { "sequence": "MTKKRKRQDDFQKVKLKVGKKKPKLENATATNFKTKAIHLPEQLKEDRTLPTNNRKLNIKDLLSQMHHYNAGVKQSALLGLKDLLSQYPFIIDAHLSNILSEVTAVFTDRDANVRLAAVQLLQFLAPKIRTEQISPFFPLVSAHLSSAMTHITEGIQEDSLKVLDVLLEHYPALITGRSSILLKNFVELISHQQLSKGLINRDRSQSWILSVNPNRRVTSQQWRLKVLARLSKFLQALADGSSRLRESEGLQEQKETPHATSNSIFINWKDHASDQQQIQVYENGGSQPNVSSQFRLRYLGAQGAVDEDLSSPENLKGFIEIIIPLLIECWIEALPPQLAAAIGNGIEREPLQVMQQVLNVISLLWKLSKQQDETHTLESWLRKNYLTDFKHHFMSHFPYALKEITKQRKKETNKSIKHCTVLSNNVDHLLLNLTLSDIMVSLANASTLQNDSSWIETIRKFVTETLKGGARLNSKQLNRLLGVSWRLIQMQPNREATEILIKAVYTLYQQRGLLLPVRTLLIKFFSKIYQKEELRSYRLRYRSRVLSRWLAGLPLQLSHLGSRNPELSTQLIDIIHTAAAQANKDLLKSLQAAALRIYDPQEGAVVVLPAESQQRLVQLLYFLPTLPADLLSRLSRCCIMGRLGSSLAATLIGILYMRSSFSGWNHSINDYLMTDVDYLSFLFSTLTGFSKEELAWLQNLRGVPHVIQTSLSPVLLYLTDLDQFLHHWDITEAVCHSLLVIPARSQSFDIMQSAISKHLVGLTVIPDSTAGCIFGVMCKLLDHTCVVSESLLPFLASCCYSLLYFLLTLEKGEAEHLKKRDKLWGVCVSILALLPRVLRLMLQSLRVSRASPEELPVVGQLLRLLLQHVPLRTHMLTNAILVQQIIKNITTLKSGSVQEQWLTDLHYCFSVYISGHPQGPSILNALY", "length": 928, "header": "tr|A0A3L7I311-1|A0A3L7I311_CRIGR Isoform 1 of Testis-expressed protein 10 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tex10 PE=3 SV=1 CANONICAL=A0A3L7I311-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FFK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I311/entry#A0A9J7FFK8-1", "sequence": { "sequence": "MQQVLNVISLLWKLSKQQDETHTLESWLRKNYLTDFKHHFMSHFPYALKEITKQRKKETNKSIKHCTVLSNNVDHLLLNLTLSDIMVSLANASTLQNDSSWIETIRKFVTETLKGGARLNSKQLNRLLGVSWRLIQMQPNREATEILIKAVYTLYQQRGLLLPVRTLLIKFFSKIYQKEELRSYRLRYRSRVLSRWLAGLPLQLSHLGSRNPELSTQLIDIIHTAAAQANKDLLKSLQAAALRIYDPQEGAVVVLPAESQQRLVQLLYFLPTLPADLLSRLSRCCIMGRLGSSLAATLIGILYMRSSFSGWNHSINDYLMTDVDYLSFLFSTLTGFSKEELAWLQNLRGVPHVIQTSLSPVLLYLTDLDQFLHHWDITEAVCHSLLVIPARSQSFDIMQSAISKHLVGLTVIPDSTAGCIFGVMCKLLDHTCVVSESLLPFLASCCYSLLYFLLTLEKGEAEHLKKRDKLWGVCVSILALLPRVLRLMLQSLRVSRASPEELPVVGQLLRLLLQHVPLRTHMLTNAILVQQIIKNITTLKSGSVQEQWLTDLHYCFSVYISGHPQGPSILNALY", "length": 574, "header": "tr|A0A9J7FFK8-1|A0A9J7FFK8_CRIGR Computationally mapped isoform of Testis-expressed protein 10 isoform X3 OS=Cricetulus griseus OX=10029 GN=Tex10 PE=4 SV=1 CANONICAL=A0A3L7I311-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FKI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I311/entry#A0A9J7FKI4-1", "sequence": { "sequence": "MTKKRKRQDDFQKVKLKVGKKKPKLENATATNFKTKAIHLPEQLKEDRTLPTNNRKLNIKDLLSQMHHYNAGVKQSALLGLKDLLSQYPFIIDAHLSNILSEVTAVFTDRDANVRLAAVQLLQFLAPKIRTEQISPFFPLLFLFLPYPIRYLGAQGAVDEDLSSPENLKGFIEIIIPLLIECWIEALPPQLAAAIGNGIEREPLQVMQQVLNVISLLWKLSKQQDETHTLESWLRKNYLTDFKHHFMSHFPYALKEITKQRKKETNKSIKHCTVLSNNVDHLLLNLTLSDIMVSLANASTLQNDSSWIETIRKFVTETLKGGARLNSKQLNRLLGVSWRLIQMQPNREATEILIKAVYTLYQQRGLLLPVRTLLIKFFSKIYQKEELRSYRLRYRSRVLSRWLAGLPLQLSHLGSRNPELSTQLIDIIHTAAAQANKDLLKSLQAAALRIYDPQEGAVVVLPAESQQRLVQLLYFLPTLPADLLSRLSRCCIMGRLGSSLAATLIGILYMRSSFSGWNHSINDYLMTDVDYLSFLFSTLTGFSKEELAWLQNLRGVPHVIQTSLSPVLLYLTDLDQFLHHWDITEAVCHSLLVIPARSQSFDIMQSAISKHLVGLTVIPDSTAGCIFGVMCKLLDHTCVVSESLLPFLASCCYSLLYFLLTLEKGEAEHLKKRDKLWGVCVSILALLPRVLRLMLQSLRVSRASPEELPVVGQLLRLLLQHVPLRTHMLTNAILVQQIIKNITTLKSGSVQEQWLTDLHYCFSVYISGHPQGPSILNALY", "length": 780, "header": "tr|A0A9J7FKI4-1|A0A9J7FKI4_CRIGR Computationally mapped isoform of Testis-expressed protein 10 isoform X2 OS=Cricetulus griseus OX=10029 GN=Tex10 PE=4 SV=1 CANONICAL=A0A3L7I311-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I311", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I311" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I311", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I311" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100775062", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100775062", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AR35-1", "protein_name": "Testis-expressed protein 10", "gene_name": "TEX10", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTKKRKRQDDFQKVKLKVGKKKPRLENATVTNFKTKTIHLPEQLKEDGTLPTNNRKLNIKDLLSQMHHYNAGVKQSALLGLKDLLSQYPFIIDAHLSNILSEVTAVFTDKDANVRLAAVQLLQFLAPKIRAEQISPFFPLVSAHLSSAMTHITEGIQEDSLKVLDILLEQYPALITGRSSILLKNFVELISHQQLSKGLVNRDRSQSWILSVNPNRRLTSQQWRLKVLVRLSKFLQALADGSSRLRESEGLQEQKENPHATSNSIFINWKEHANDQQHIQVYEHGGSQPNVSSQFRLRYLVGGLGNVDEGLSSTENLKGFIEIIIPLLIECWIEAVPPHLAASVGNGIEREPLQVMQQVLNIISLLWKLSKQHDETHKLESWLRKNYLIDFKHHFMNNFPYALKEISKHRRKETNKSIKHCTVLSNNVDHLLLNLTLSDIMVSLANASTLQKDSNWIEMIRKFITETLEDGSRLNSKQLNRLLGVSWRLMQIQPNREATESLIKAVYTLYQQRCLSLPVRTLLLKFFSKIYQKEELRSYRVRYRSKVLSRWLAGLPLQLAHLGSRNPELSTQLIDIIHTAAARANKELLRSLQVTALRIYDPQEGTVVVLPAESQQLLVQLVYFLPSLPADLLSRLSRCCIMGRLSSSLAAMLIGILHMRSSFSGWKSSVKEWLMSDVDYFSFLFSTLTGFSKEELTWLQSLRGVPHVIQTQLSPVLLYLTDLDQFLHHWDVTETVCHNLLVIPARSQSFDVLQSAISKHLVGLTVIPDSTAGCVLGVICKLLDHTCVLSETLLPFLASCCYSLLYFLLTLEKGEAEHLRKRDKLWGVCVSILALLPRVLRLMLQSLRVSRAGPEELPVVGQLLRLLLQHAPLRTHMLSNAILVQQIIKNITTLKSGGAQEQWLTDLHYCFNVYITGHPQGPSALSTVY", "length": 929 }, "evidence": [ { "id": "A0A3L7I311", "url": "https://omabrowser.org/oma/group/A0A3L7I311/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A3Q1M1K0-1", "protein_name": "Testis-expressed protein 10", "gene_name": "TEX10", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTKKRKRQDDFQKVKLKVGKKKPRSENATLTNFKTKTIHLPEQLKEDVTLPTNNRKLNIKDLLSQMHHYNAGVKQSALLGLKDLLSQYPYIIDAHLSNILSEVTAVFTDKDANVRLAAVQLLQFLAPKIRAEQISPFFPLVSAHLSSAMTHITEGIQEDSLKVLDILLEQYPALITDRSSILLKNFVELISHQQPSKGLVNRDRSQSWILSVNPNRRLTSQQWRLKVLVRLSKFLQALTDGSSRLRESEGLQEQKENPHATSNSIFINWKEHANDQQHIQVYENGGSQPNVSSQFRLRYLVGGLGTVDEGLSSTENLKGFIEIIIPLLIECWIEAVPPQLAASVGNGIEREPLQVMQQVLNIISLLWKLSKQHDETHKLESWLRKNYLIDFKHHFMSNFPYALKEITKQKRKETNKSIKHCTILSHNVDHLLLNLTLSDIMVSLANASTLQKDSSWIERIRKFVTETLEDGSRLNSKQLNRLLGVSWRLMQIQPNREATESLIKAVYTLYQQRGLLIPVRTLLLKFFSKIYQKEELRAYRIRYRSKVLSRWLAGLPLQLAHLGSRNPELSTQLIDIIHTAAARANKELLKSLQVTALRIYDPQEGTVVVLPAESQQLLVQLVYFLPSLPADLLSRLSRCCIMGRLSADLAAMLIGILHMRSSFSGWKSSVKEQNGSVQLNISNADYFSFLFSTLTGFSKEELTWLQSLRGVPHVIQTQLSPMLLYLTDLDQFLHHWDVTEVGLTVIPDSTAGCVLGVICKLLDHTCVLSETLLPFLASCCYSLLYFLLTLEKGEAEHLRKRDKLWGVCVSVLALLPRVLRLMLQSLRVNRAGPEELPVVGQLLRLLLQHAPLRTHMLTNAILVQQIIKNITTLKSGGVQEQWLTDLHYCFNVYITGHPQGPNALSTVY", "length": 908 }, "evidence": [ { "id": "A0A3L7I311", "url": "https://omabrowser.org/oma/group/A0A3L7I311/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D4A401-1", "protein_name": "Testis expressed 10", "gene_name": "Tex10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKKRKRQDDFQKVKLKVGKKKPKLENATATNFKTKAIHLPEQLKEDRTLPTNNRKLNIKDLLSQMHHYNGGVKQSALLGLKDLLSQYPCIIDAHLSNILSEVTAVFTDRDANVRLAAVQLLQFLAPKIRTEQISPFFPLVSAHLSSAMTHITEGIQEDSLKVLDVLLEHYPALITGRSSILLKNFVELISHQQLSKGLVNRDRPQSWILSVNPNRRVTSQQWRLKVLARLSKFLQALADGSSRLRESEGLQEQKETPHATSNSIFINWKDHANDQQQIQVYENGGSQPNVSSQFRLRYLVGTLGTVDEDPSSPENLKGFIEIIIPLLIECWIEALPPQLAASVGSGVEREPLQVMQQVLNVISLLWKLSKQQDETHTLESWLRKNYLSDFKHHFMTHFPYALKEMTKQRKKETNKSIKHCTVLSNNVDHLLLNLTLSDIMVSLANASTLQNDSSWIETIRKFVTETLKGGARLNSKQLNRLLGVSWRLIQMQPNRDATENLIKAVYALYQQRGLLLPVRTLLIKFFSKIYQKEELRSYRLRYRSRVLSRWLAGLPLQLSYLGSRNPELSTQLIDIIHTAASQANKDLLKNLQAAALRIYDPQEGAVVVLPAESQQRLVQLLYFLPTLPADLLSQLSRCCIMGRLGSSLAGTLIGILYMRSSFSGWSHSVNDCLMTDVDYLSFLFSTLTGFSKEELAWLQNLRGVPHVIQTSLSPVLLYLTDLDQFLHHWDITEAVCHSLLVIPARSQSFDIMQSAISKHLVGLTVIPDSTAGCIFGVMCKLLDHTCVVNEALLPFLASCCYSLLYFLLTLEKGEAEHLKKRDKLWEVCVSILALLPRVLRLMLQSLRVNRASPEELPVVGQLLRLLLQHVPLRSHMLTNAILVQQIIKNITTLKSGSVQEQWLTDLHYCFSVYISGHPQGPSILNALY", "length": 929 }, "evidence": [ { "id": "A0A3L7I311", "url": "https://omabrowser.org/oma/group/A0A3L7I311/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3URQ0-1", "protein_name": "Testis-expressed protein 10", "gene_name": "Tex10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKKRKRQDDFQKVKLKVGKKKPKLENATATNFKTKAIHLPEQLKEDRTLPTNNRKLNIKDLLSQMHHYSGGVKQSALLGLKDLLSQYPFIIDAHLSNILSEVTAVFTDRDANVRLAAVQLLQFLAPKIRTEHISPFFPLVSAHLSSAMTHITEGIQEDSLKVLDILLEHYPALITGRSSILLKNFVELISHQQLSKGLVNRDRSQSWILSVNPNRRVTSQQWRLKVLARLSKFLQALADGSSRLRESEGLQEQKETPHATSNSIFINWKDHANDQQQIQVYENGGSQPNVSSQFRLRCLGTLGTVDEDLSSPENLKGFIEIIIPLLIECWIEALPPQLAASVGSGVEREPLQVMQQVLNVISLLWKLSKQQDETHTLESWLRKNYLTDFKHHFMSHFPYALKEITKQRKKDTNKSIKHCTVLSNNVDHLLLNLTLSDIMVSLANASTLQNDSSWIETIRKFVTETLKGGTRLNSKQLNRLLGVSWRLIQMQPNRDATENLIKAVYTLYQQRGLLLPVRTLLIKFFSKIYQKEELRSYRLRYRSKVLSRWLAGLPLQLSYLGSRNPELSTQLIDIIHTAASQANKDLLKNLQAAALRIYDPQEGAVVVLPAESQQRLVQLLYFLPTLPADLLSQLSRCCIMGRLGSSLAVTLIGILYMRSSFSGWSHSVNDCLMTDVDYLSFLFSTLTGFSKEELTWLQNLRGVPHVVQTSLSPVLLYLTDLDQFLHHWDITEAVCHSLLVIPARSQSFDIMQSAISKHLVGLTVIPDSTAGCIFGVMCKLLDHTCVVNEALLPFLASCCYSLLYFLLTLEKGDAEHLKKRDKLWEVCVSILALLPRVLRLMLQSLRVNRASPEELPVVGQLLRLLLQHVPLRSHMLTNAILVQQIIKNITTLKSGSVQEQWLTDLHYCFSVYISGHPQGPSILNALY", "length": 928 }, "evidence": [ { "id": "A0A3L7I311", "url": "https://omabrowser.org/oma/group/A0A3L7I311/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q55DQ9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGRSAPKKTLQPSLDFKVKKKKLGKKPPPNPNITVTTFKSKALNMPGQNIVEEKDDLVNHRNLTLKDLLTKLNHYNDQVKKDAVTGIRDLILKHPSVLFVHLGAIMNKLVEVINDLDKDVRHCTHTLISTILPMLDEISISPFIPLFSVYINSGMTHLKTTIRLDSLRLLDIFIDHYPNLVSRSCHQMIPNYIDLLKRVSGAATVATISTSTSSSANVPISASVPVSQQKNKSSTASSTPKANSLHTRVMILKSLFKLIKVLLHEPDLSFSSLLNKIHKQRENTQIIDGKMAIDCSLTYQAYNDRKVFPDLFSKYLVKNNEQQQLNSDGTVKSLFPTILETSEEVKQFSSTLLPILIDLWLELGPSNPGISFQVLEDLELVVSIIQLLVHCLKENFSTTDFYEQLRKDYIKFFSVHFPFYVGSPSNPDSKEWIISCSINSLMTQTASHFLGYSPSISNVDQTINGWYQPFFEFIEDALNGKLIDEKVEATKGQSIKTHISNLLWIVKIILPILSSTQSESILNSFISFDEKCHPHSTSKKACVFFIKELIDIQSNPLLSNVKSFKNIIEWGLTSLPKLLWKLGNSDNDTSLMILNILLSVGRDKSKIKQYDSIQNALVPFFFTISKPTPQFPNGKQIYGPFSSLPLNIQFLALNTLYYFSSLNKIMIRSLIAICRSNKSSPEIISIVLDLIHNLYLVGTLSLSHYTAFCIAITLSITSKEIEDNTNNVIMIDEEKIQEQEKIIKKLCWNINSLRLSNSIENILEPMTEPFISELKKISTNFQDNNNENSGDSLNYILSLILSCFTDKNDYNNEIREKEFKSLSNELIITITNSIFIYIFQSIKFINSTSTKIYDLNIILKIIQLDNSNQILINILNLISSKLNVGNNQVEKNNNNQYSILSLIELFKSKELYEIFQLSNVKSIVGSIVKKVEKSVSTQLSTEKQLLEKLLSEVKLLFNE", "length": 959 }, "evidence": [ { "id": "A0A3L7I311", "url": "https://omabrowser.org/oma/group/A0A3L7I311/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9NXF1-1", "protein_name": "Testis-expressed protein 10", "gene_name": "TEX10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027258984", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258984" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I349", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I349" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Polr1e", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I349", "locus": {} } ], "crossref": [ { "id": "100751282", "url": "https://www.ncbi.nlm.nih.gov/gene/100751282", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009668", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009668", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751282", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751282", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3L7I349", "url": "https://www.orthodb.org/?gene=A0A3L7I349", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14440", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14440", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06870", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06870", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027258984", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027258984", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7I349", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I349", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7I349-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I349-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATLESSGLDSQSRDMETEVQQSARWLYCGEPDDRQKAVLVQFSNGKLQNPGNMRFTLYNSNDLVNPRLKNQRILAAETDRLSYVGNNFGTGALKCNTLCRHFVGILNKTSGQMEVYDAELFNMQPLFAEDAIEQEPPPENQAKTFREKLDSCIEAFGSTKQKRSLNSRRMNKVGSESLNLTVTKAAENIIDTKGVNALVSDAMQDDLQDDSLYLPPCHADATKPEDVYRFEDILSQAEYDALESPSEAFRKVTSEDILKMIEENRHCSFVIEMLKSLPSNEESRDRQARSIWFLDALIRFRAQKVIKGKSALGPGIPHIINTKLLKNFTCLTYNNGSLRNLISSSMKAKITAFAIILALHINSFQIDLTLLQGDLKLSEKRMIEIAKAMRLKISKRKVTLADGREEDHRLGTLSVPLPPPQTSDRQSKRKKMN", "length": 434, "header": "tr|A0A3L7I349-1|A0A3L7I349_CRIGR Isoform 1 of DNA-directed RNA polymerase I subunit RPA49 OS=Cricetulus griseus OX=10029 GN=Polr1e PE=3 SV=1 CANONICAL=A0A3L7I349-1" }, "isoforms": [ { "isoform_ac": "A0A3L7I349-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I349/entry#A0A3L7I349-1", "sequence": { "sequence": "MATLESSGLDSQSRDMETEVQQSARWLYCGEPDDRQKAVLVQFSNGKLQNPGNMRFTLYNSNDLVNPRLKNQRILAAETDRLSYVGNNFGTGALKCNTLCRHFVGILNKTSGQMEVYDAELFNMQPLFAEDAIEQEPPPENQAKTFREKLDSCIEAFGSTKQKRSLNSRRMNKVGSESLNLTVTKAAENIIDTKGVNALVSDAMQDDLQDDSLYLPPCHADATKPEDVYRFEDILSQAEYDALESPSEAFRKVTSEDILKMIEENRHCSFVIEMLKSLPSNEESRDRQARSIWFLDALIRFRAQKVIKGKSALGPGIPHIINTKLLKNFTCLTYNNGSLRNLISSSMKAKITAFAIILALHINSFQIDLTLLQGDLKLSEKRMIEIAKAMRLKISKRKVTLADGREEDHRLGTLSVPLPPPQTSDRQSKRKKMN", "length": 434, "header": "tr|A0A3L7I349-1|A0A3L7I349_CRIGR Isoform 1 of DNA-directed RNA polymerase I subunit RPA49 OS=Cricetulus griseus OX=10029 GN=Polr1e PE=3 SV=1 CANONICAL=A0A3L7I349-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"XP_027260891", "name": "estradiol 17 beta-dehydrogenase 5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260891" }, "gene_names": [ { "name": "LOC100770100", "type": "recommended", "evidence": [ { "id": "A0A3L7I355", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I355" } ] }, { "name": "LOC100770100", "type": "synonym", "evidence": [ { "id": "XP_027260891", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260891" } ] } ], "protein_names": [ { "name": "Estradiol 17 beta-dehydrogenase 5 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A3L7I355", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I355/entry#names_and_taxonomy" } ] }, { "name": "estradiol 17 beta-dehydrogenase 5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027260891", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260891" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027260891", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260891" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I355", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I355" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100770100", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I355", "locus": {} } ], "crossref": [ { "id": "cd19108", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19108", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100770100", "url": "https://www.ncbi.nlm.nih.gov/gene/100770100", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020471", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020471", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036812", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036812", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044482", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044482", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770100", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770100", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3L7I355", "url": "https://www.orthodb.org/?gene=A0A3L7I355", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11732", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11732", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00248", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00248", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027260891", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260891", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7I355", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I355", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7I355-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I355-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K632", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K632", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K632-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K632-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNSKQQTVRLSDGHFIPVLGFGTYATPEEPKTKVTEATKIAIDAGFRHIDSASMYQNEEEIGLAIRSKIAEGTVKREHIFYTSKLWCTFHRPELVQFCLEQSLKKLQLDYVDLYLIHFPVSLKPGENYLPKDENGKFIFDIVDLCATWEAMEKCKDAGLTKSIGVSNFNRRQLEMILNKPGLKHKPVCNQVECHPYLNQRKLLDFCKSKDIVLVAYSALGSHREKTWVDSNLPILLDDPVLGSMAKKYKRTPALIALRYQLQRGVVVLAKSFTEKRIKENMQVFEFQLTSEDMKVLDGLNKNIRYISGDGFKGHPGFPFSDEY", "length": 323, "header": "tr|A0A3L7I355-1|A0A3L7I355_CRIGR Isoform 1 of Estradiol 17 beta-dehydrogenase 5 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100770100 PE=3 SV=1 CANONICAL=A0A3L7I355-1" }, "isoforms": [ { "isoform_ac": "A0A3L7I355-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I355/entry#A0A3L7I355-1", "sequence": { "sequence": "MNSKQQTVRLSDGHFIPVLGFGTYATPEEPKTKVTEATKIAIDAGFRHIDSASMYQNEEEIGLAIRSKIAEGTVKREHIFYTSKLWCTFHRPELVQFCLEQSLKKLQLDYVDLYLIHFPVSLKPGENYLPKDENGKFIFDIVDLCATWEAMEKCKDAGLTKSIGVSNFNRRQLEMILNKPGLKHKPVCNQVECHPYLNQRKLLDFCKSKDIVLVAYSALGSHREKTWVDSNLPILLDDPVLGSMAKKYKRTPALIALRYQLQRGVVVLAKSFTEKRIKENMQVFEFQLTSEDMKVLDGLNKNIRYISGDGFKGHPGFPFSDEY", "length": 323, "header": "tr|A0A3L7I355-1|A0A3L7I355_CRIGR Isoform 1 of Estradiol 17 beta-dehydrogenase 5 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100770100 PE=3 SV=1 CANONICAL=A0A3L7I355-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K632-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I355/entry#A0A9J7K632-1", "sequence": { "sequence": "MNSKQQTVRLSDGHFIPVLGFGTYATPEEPKTKVTEATKIAIDAGFRHIDSASMYQNEEEIGLAIRSKIAEGTVKREHIFYTSKLWCTFHRPELVQFCLEQSLKKLQLDYVDLYLIHFPVSLKAMEKCKDAGLTKSIGVSNFNRRQLEMILNKPGLKHKPVCNQVECHPYLNQRKLLDFCKSKDIVLVAYSALGSHREKTWVDSNLPILLDDPVLGSMAKKYKRTPALIALRYQLQRGVVVLAKSFTEKRIKENMQVFEFQLTSEDMKVLDGLNKNIRYISGDGFKGHPGFPFSDEY", "length": 297, "header": "tr|A0A9J7K632-1|A0A9J7K632_CRIGR Computationally mapped isoform of Estradiol 17 beta-dehydrogenase 5 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100770100 PE=3 SV=1 CANONICAL=A0A3L7I355-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I355", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I355" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770100", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770100", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I355", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I355" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor", "id": "GO:0016616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016616", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I355", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I355" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3L7I355", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I355" }, { "id": "PF00248", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00248" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NADP-dependent oxidoreductase", "eco_id": "ECO_0000259", "start_pos": 19, "end_pos": 300, "start_aa": "Leu", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7I380-1", "uniprot_ac": "A0A3L7I380", "uniprot_id": "A0A3L7I380_CRIGR", "mass": { "chemical_mass": 29107.0, "monoisotopic_mass": 29107.0 }, "refseq": { "ac": "XP_016832398", "name": "coiled-coil domain-containing protein 107 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016832398" }, "gene_names": [ { "name": "Ccdc107", "type": "recommended", "evidence": [ { "id": "A0A3L7I380", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I380" } ] }, { "name": "Ccdc107", "type": "synonym", "evidence": [ { "id": "XP_016832398", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016832398" } ] } ], "protein_names": [ { "name": "Coiled-coil domain-containing protein 107 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A3L7I380", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I380/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 107 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_016832398", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016832398" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 339 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614108.1) and transcript sequence (IACG01059394.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_016832398.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016832398", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016832398" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I380", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I380" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ccdc107", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I380", "locus": {} } ], "crossref": [ { "id": "100773807", "url": "https://www.ncbi.nlm.nih.gov/gene/100773807", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR038779", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038779", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773807", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773807", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3L7I380", "url": "https://www.orthodb.org/?gene=A0A3L7I380", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR37345", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37345", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37345:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37345:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_016832398", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016832398", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7I380", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I380", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7I380-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I380-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GS58", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GS58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GS58-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GS58-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGAGPVSSVLGLLLVSALFGVLGERPSPDQGAHSERRSQVGPGSTEPRRRPPPKDQRERARAGALPLGALYTAAVVAFVLYKCLQGPDEAAILQEEKNKKKSLQSEQQLMQLTQQLAQTEQHLNNLMTQLDPLFERVTTLVGTQRELLNMKLKTIHQLLQDCNPDLSVHIPGKRSGGDGLETEAGKLEQADLSLTKATIPFPKHLGKEDQQGAGDCEAWEGPINWSPDSWNLAPSWEVEQGLRRRWHKTVTKDPARNGEQPLKG", "length": 265, "header": "tr|A0A3L7I380-1|A0A3L7I380_CRIGR Isoform 1 of Coiled-coil domain-containing protein 107 isoform X2 OS=Cricetulus griseus OX=10029 GN=Ccdc107 PE=4 SV=1 CANONICAL=A0A3L7I380-1" }, "isoforms": [ { "isoform_ac": "A0A3L7I380-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I380/entry#A0A3L7I380-1", "sequence": { "sequence": "MAGAGPVSSVLGLLLVSALFGVLGERPSPDQGAHSERRSQVGPGSTEPRRRPPPKDQRERARAGALPLGALYTAAVVAFVLYKCLQGPDEAAILQEEKNKKKSLQSEQQLMQLTQQLAQTEQHLNNLMTQLDPLFERVTTLVGTQRELLNMKLKTIHQLLQDCNPDLSVHIPGKRSGGDGLETEAGKLEQADLSLTKATIPFPKHLGKEDQQGAGDCEAWEGPINWSPDSWNLAPSWEVEQGLRRRWHKTVTKDPARNGEQPLKG", "length": 265, "header": "tr|A0A3L7I380-1|A0A3L7I380_CRIGR Isoform 1 of Coiled-coil domain-containing protein 107 isoform X2 OS=Cricetulus griseus OX=10029 GN=Ccdc107 PE=4 SV=1 CANONICAL=A0A3L7I380-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GS58-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I380/entry#A0A9J7GS58-1", "sequence": { "sequence": "MCHSKLRQEDSKSKACLGNLARSYLKNGRVGMLNKKAELCDQSSDSYHSDHIPKSVLAVWPYVGILTCCFVFWVSSRTRNYWDSEGPDEAAILQEEKNKKKSLQSEQQLMQLTQQLAQTEQHLNNLMTQLDPLFERVTTLVGTQRELLNMKLKTIHQLLQDCNPDLSVHIPGKRSGGDGLETEAGKLEQADLSLTKATIPFPKHLGKEDQQGAGDCEAWEGPINWSPDSWNLAPSWEVEQGLRRRWHKTVTKDPARNGEQPLKG", "length": 264, "header": "tr|A0A9J7GS58-1|A0A9J7GS58_CRIGR Computationally mapped isoform of Coiled-coil domain-containing protein 107 isoform X3 OS=Cricetulus griseus OX=10029 GN=Ccdc107 PE=4 SV=1 CANONICAL=A0A3L7I380-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I380", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I380" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I380", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I380" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773807", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773807", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 225, "end_pos": 227, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 225, "end_pos": 227 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7I3A3-1", "uniprot_ac": "A0A3L7I3A3", "uniprot_id": "A0A3L7I3A3_CRIGR", "mass": { "chemical_mass": 32404.0, "monoisotopic_mass": 32404.0 }, "refseq": { "ac": "XP_007642741", "name": "myb/SANT-like DNA-binding domain-containing protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642741" }, "gene_names": [ { "name": "Msantd3", "type": "recommended", "evidence": [ { "id": "A0A3L7I3A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3A3" } ] }, { "name": "Msantd3", "type": "synonym", "evidence": [ { "id": "XP_007642741", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642741" } ] } ], "protein_names": [ { "name": "Myb/SANT-like DNA-binding domain-containing protein 3", "type": "recommended", "evidence": [ { "id": "A0A3L7I3A3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3A3/entry#names_and_taxonomy" } ] }, { "name": "myb/SANT-like DNA-binding domain-containing protein 3", "type": "synonym", "evidence": [ { "id": "XP_007642741", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642741" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614021.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007642741", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642741" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I3A3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3A3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Msantd3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3A3", "locus": {} } ], "crossref": [ { "id": "103158546", "url": "https://www.ncbi.nlm.nih.gov/gene/103158546", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028002", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028002", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:103158546", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103158546", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QTVAKEW", "url": "https://omabrowser.org/oma/group/QTVAKEW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7I3A3", "url": "https://www.orthodb.org/?gene=A0A3L7I3A3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21632", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21632", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21632:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21632:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13873", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13873", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007642741", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642741", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7I3A3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3A3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7I3A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3A3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQNNEIIKPAKYFSELEKSILLALVEKYKYVLECKKSDARTIALKQRTWQALAHEYNSQPSVSLRDFKQLKKCWENIKARTKKIMAHERREKVKRSGSPLLSNHVLGKEKISNMLPEQLYFLQSPPEEEPEYHQDAAVQESFPVSNRELCDDEKEFVHFPVCEGTSQPEPSCSAVRVTANKNYRSKTSQEGALKKMHEEEHHQQMSILQLQLIQMNEVHVAKIQQIERECEMAEEEHRVKMEVLNKKKMYWERKLQTFTKEWPVSSFNRPFPNSP", "length": 275, "header": "tr|A0A3L7I3A3-1|A0A3L7I3A3_CRIGR Isoform 1 of Myb/SANT-like DNA-binding domain-containing protein 3 OS=Cricetulus griseus OX=10029 GN=Msantd3 PE=3 SV=1 CANONICAL=A0A3L7I3A3-1" }, "isoforms": [ { "isoform_ac": "A0A3L7I3A3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3A3/entry#A0A3L7I3A3-1", "sequence": { "sequence": "MQNNEIIKPAKYFSELEKSILLALVEKYKYVLECKKSDARTIALKQRTWQALAHEYNSQPSVSLRDFKQLKKCWENIKARTKKIMAHERREKVKRSGSPLLSNHVLGKEKISNMLPEQLYFLQSPPEEEPEYHQDAAVQESFPVSNRELCDDEKEFVHFPVCEGTSQPEPSCSAVRVTANKNYRSKTSQEGALKKMHEEEHHQQMSILQLQLIQMNEVHVAKIQQIERECEMAEEEHRVKMEVLNKKKMYWERKLQTFTKEWPVSSFNRPFPNSP", "length": 275, "header": "tr|A0A3L7I3A3-1|A0A3L7I3A3_CRIGR Isoform 1 of Myb/SANT-like DNA-binding domain-containing protein 3 OS=Cricetulus griseus OX=10029 GN=Msantd3 PE=3 SV=1 CANONICAL=A0A3L7I3A3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I3A3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3A3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I3A3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3A3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:103158546", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103158546", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A3I3-1", "protein_name": "Myb/SANT-like DNA-binding domain-containing protein 3", "gene_name": "Msantd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQNNEIIKPAKYFSELEKSILLALVEKYKYVLECKKSDARTIALKQRTWQALAHEYNSQPSVSLRDFKQLKKCWENIKARTKKIMAHERREKVKRSGSPLLSTHVLDKEKIGSMLPEQLYFLQSPPEEEPEYHQDAAAQESFAVSNRELCDDEKEFVHFPVCEGTSQPEPSCSAVRITANKNYRSKTPQEGALKKMHEEEHHQQMSILQLQLIQMNEVHVAKIQQIERECEMAEEEHRIKMEVLNKKKMYWERKLQTFTKEWPVSSFNRPFPNSP", "length": 275 }, "evidence": [ { "id": "A0A3L7I3A3", "url": "https://omabrowser.org/oma/group/A0A3L7I3A3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BT69-1", "protein_name": "Myb/SANT-like DNA-binding domain-containing protein 3", "gene_name": "C2H9ORF30", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQNEIIKPAKYFSEVEKSVLLALVEKYRYVLECKKSDARTIALKQRTWQALAHEYNSQPSVSLRDFKQLKKCWENIKARTKKIMAHERREKVKSISPLINTHIIGKEKIASIMPEQIYFLQSPPEEDSEYQPDASSQESFVVSNRELCDEEKELIHFPVCEGTSQPEPSCSDVRIAADKNYRSKASQESALKKMHEEEHHQQMSILQLQLIQMNEVHVAKIQQIERECEMAEEEHRIKMEVLNKKKMYWERKLQTITKEWPVSSFNRPFPNSP", "length": 273 }, "evidence": [ { "id": "A0A3L7I3A3", "url": "https://omabrowser.org/oma/group/A0A3L7I3A3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q0III0-1", "protein_name": "Myb/SANT-like DNA-binding domain-containing protein 3", "gene_name": "MSANTD3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQNNEIIKPAKYFSELEKSILLALVEKYKYVLECKKSDARTIALKQRTWQALAHEYNSQPSVSLRDFKQLKKCWENIKARTKKIMAHERREKVKRSVSPLLSTHVLGKEKIASMLPEQLYFLQSPPEEEPEYHAEAAAQESFAVSNRELCDDEKEFIHFPVCEGTSQPEPSCSAVRITANKNYRSKTSQEGALKKMHEEEHHQQMSILQLQLIQMNEVHVAKIQQIERECEMAEEEHRIKMEVLNKKKMYWERKLQTFTKEWPVSSFNRPFPNSP", "length": 275 }, "evidence": [ { "id": "A0A3L7I3A3", "url": "https://omabrowser.org/oma/group/A0A3L7I3A3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q96H12-1", "protein_name": "Myb/SANT-like DNA-binding domain-containing protein 3", "gene_name": "MSANTD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQNNEIIKPAKYFSELEKSILLALVEKYKYVLECKKSDARTIALKQRTWQALAHEYNSQPSVSLRDFKQLKKCWENIKARTKKIMAHERREKVKRSVSPLLSTHVLGKEKIASMLPEQLYFLQSPPEEEPEYHPDASAQESFAVSNRELCDDEKEFIHFPVCEGTSQPEPSCSAVRITANKNYRSKTSQEGALKKMHEEEHHQQMSILQLQLIQMNEVHVAKIQQIERECEMAEEEHRIKMEVLNKKKMYWERKLQTFTKEWPVSSFNRPFPNSP", "length": 275 }, "evidence": [ { "id": "A0A3L7I3A3", "url": "https://omabrowser.org/oma/group/A0A3L7I3A3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CR78-1", "protein_name": "Myb/SANT-like DNA-binding domain-containing protein 3", "gene_name": "Msantd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQNNEIIKPAKYFSELEKSILLALVEKYKYVLECKKSDARTIALKQRTWQALAHEYNSQPSVSLRDFKQLKKCWENIKARTKKIMAHERREKVKRSGSPLLSSHVLDKEKISSMLPEQLYFLQSPPEEEPEYHQDAAAQESFAVSNRELCEDEKEFGPFPVCEGTSQPEPSCSAVRITANKNYRSKTPQEGALKKMHEEEHHQQMSILQLQLIQMNEVHVAKIQQIERECEMAEEEHRIKMEVLNKKKMYWERKLQTFTKEWPVSSFNRPFPNSP", "length": 275 }, "evidence": [ { "id": "A0A3L7I3A3", "url": "https://omabrowser.org/oma/group/A0A3L7I3A3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], 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"uniprot_canonical_ac": "A0A3L7I3D1-1", "uniprot_ac": "A0A3L7I3D1", "uniprot_id": "A0A3L7I3D1_CRIGR", "mass": { "chemical_mass": 21144.0, "monoisotopic_mass": 21144.0 }, "refseq": { "ac": "XP_007643662", "name": "dynactin subunit 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643662" }, "gene_names": [ { "name": "Dctn3", "type": "recommended", "evidence": [ { "id": "A0A3L7I3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3D1" } ] }, { "name": "Dctn3", "type": "synonym", "evidence": [ { "id": "XP_007643662", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643662" } ] } ], "protein_names": [ { "name": "Dynactin subunit 3 isoform X3", "type": "synonym", "evidence": [ { "id": "A0A3L7I3D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3D1/entry#names_and_taxonomy" } ] }, { "name": "dynactin subunit 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007643662", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643662" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 73 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614108.1) and transcript sequence (JI882022.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007643662", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643662" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I3D1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3D1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dctn3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3D1", "locus": {} } ], "crossref": [ { "id": "100753423", "url": "https://www.ncbi.nlm.nih.gov/gene/100753423", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009991", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009991", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753423", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753423", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3L7I3D1", "url": "https://www.orthodb.org/?gene=A0A3L7I3D1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JAU0", "url": "https://www.orthodb.org/?gene=A0A9J7JAU0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28360", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28360", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28360:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28360:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07426", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07426", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007643662", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007643662", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7I3D1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3D1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7I3D1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3D1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JAU0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JAU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JAU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JAU0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAALTDVQRLRSRVEELERWVYGPGGTRGSRKVADGLVKVQVALGNIASKRERVKILYKKIEDLIKYLDPEYIDRIAIPDASKLQFILAEEQFILSQAALLQQVDALVPMLDSASIKAVPEHAARLQRLAQIHIQQQDQCMEISEESKALLEEYNKTTMLLSKQFVQWDELLCQLEAAKQVKPAEE", "length": 186, "header": "tr|A0A3L7I3D1-1|A0A3L7I3D1_CRIGR Isoform 1 of Dynactin subunit 3 isoform X3 OS=Cricetulus griseus OX=10029 GN=Dctn3 PE=4 SV=1 CANONICAL=A0A3L7I3D1-1" }, "isoforms": [ { "isoform_ac": "A0A3L7I3D1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3D1/entry#A0A3L7I3D1-1", "sequence": { "sequence": "MAALTDVQRLRSRVEELERWVYGPGGTRGSRKVADGLVKVQVALGNIASKRERVKILYKKIEDLIKYLDPEYIDRIAIPDASKLQFILAEEQFILSQAALLQQVDALVPMLDSASIKAVPEHAARLQRLAQIHIQQQDQCMEISEESKALLEEYNKTTMLLSKQFVQWDELLCQLEAAKQVKPAEE", "length": 186, "header": "tr|A0A3L7I3D1-1|A0A3L7I3D1_CRIGR Isoform 1 of Dynactin subunit 3 isoform X3 OS=Cricetulus griseus OX=10029 GN=Dctn3 PE=4 SV=1 CANONICAL=A0A3L7I3D1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JAU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3D1/entry#A0A9J7JAU0-1", "sequence": { "sequence": "MAALTDVQRLRSRVEELERWVYGPGGTRGSRKVADGLVKVQVALGNIASKRERVKILYKKIEDLIKYLDPEYIDRIAIPDASKLQFILAAVPEHAARLQRLAQIHIQQQDQCMEISEESKALLEEYNKTTMLLSKQFVQWDELLCQLEAAKQVKPAEE", "length": 158, "header": "tr|A0A9J7JAU0-1|A0A9J7JAU0_CRIGR Computationally mapped isoform of Dynactin subunit 3 isoform X4 OS=Cricetulus griseus OX=10029 GN=Dctn3 PE=4 SV=1 CANONICAL=A0A3L7I3D1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I3D1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3D1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I3D1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3D1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753423", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753423", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I3D1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3D1" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I3D1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3D1" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I3D1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3D1" } ], "pmid": "" }, { "name": "dynactin complex", "id": "GO:0005869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005869", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I3D1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3D1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cytoskeleton-dependent cytokinesis", "id": "GO:0061640", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061640", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I3D1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3D1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 155, "end_pos": 157 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7I3I3-1", "uniprot_ac": "A0A3L7I3I3", "uniprot_id": "A0A3L7I3I3_CRIGR", "mass": { "chemical_mass": 22028.0, "monoisotopic_mass": 22028.0 }, "refseq": { "ac": "XP_035294960", "name": "charged multivesicular body protein 6-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294960" }, "gene_names": [ { "name": "LOC100750796", "type": "recommended", "evidence": [ { "id": "A0A3L7I3I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3I3" } ] }, { "name": "LOC100750796", "type": "synonym", "evidence": [ { "id": "XP_035294960", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294960" } ] } ], "protein_names": [ { "name": "Charged multivesicular body protein 6-like", "type": "synonym", "evidence": [ { "id": "A0A3L7I3I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3I3/entry#names_and_taxonomy" } ] }, { "name": "charged multivesicular body protein 6-like", "type": "synonym", "evidence": [ { "id": "XP_035294960", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294960" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. 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record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613974.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007642268", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642268" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I3P3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3P3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Fsbp", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3P3", "locus": {} } ], "crossref": [ { "id": "103162160", "url": "https://www.ncbi.nlm.nih.gov/gene/103162160", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028002", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028002", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:103162160", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103162160", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ERNNLPC", "url": "https://omabrowser.org/oma/group/ERNNLPC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7I3P3", "url": "https://www.orthodb.org/?gene=A0A3L7I3P3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15386", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15386", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15386:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15386:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13873", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13873", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007642268", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007642268", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7I3P3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3P3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7I3P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3P3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVGKARSSNFTLSEKLDLLSLVKPYVKILEEHTNKNSVIVEKNRCWDVIAVNYNAIGVDRPPRTAQGLRSLYKRLKEYAKQELLQQKEAQSDFKSSISEPTKKVMEMIPQISSFCLIRDRNHIQSANLDEAAQAGTSSLQVMVDHHPVAITVEVKQEEDIKSSPPLFPNPQHNDTSEQREEHELVHVMEEPLSPSLSSVDMRMTSSPSSIPRRDDFFHHESGEHFRSLLRYDPQILQMLKEEHQIILENQKNFGLYVQEKRDGLRRRQQLEEELLRAKIEVEKLKATRLRHDLTEYSSL", "length": 299, "header": "tr|A0A3L7I3P3-1|A0A3L7I3P3_CRIGR Isoform 1 of Fibrinogen silencer-binding protein OS=Cricetulus griseus OX=10029 GN=Fsbp PE=4 SV=1 CANONICAL=A0A3L7I3P3-1" }, "isoforms": [ { "isoform_ac": "A0A3L7I3P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3P3/entry#A0A3L7I3P3-1", "sequence": { "sequence": "MVGKARSSNFTLSEKLDLLSLVKPYVKILEEHTNKNSVIVEKNRCWDVIAVNYNAIGVDRPPRTAQGLRSLYKRLKEYAKQELLQQKEAQSDFKSSISEPTKKVMEMIPQISSFCLIRDRNHIQSANLDEAAQAGTSSLQVMVDHHPVAITVEVKQEEDIKSSPPLFPNPQHNDTSEQREEHELVHVMEEPLSPSLSSVDMRMTSSPSSIPRRDDFFHHESGEHFRSLLRYDPQILQMLKEEHQIILENQKNFGLYVQEKRDGLRRRQQLEEELLRAKIEVEKLKATRLRHDLTEYSSL", "length": 299, "header": "tr|A0A3L7I3P3-1|A0A3L7I3P3_CRIGR Isoform 1 of Fibrinogen silencer-binding protein OS=Cricetulus griseus OX=10029 GN=Fsbp PE=4 SV=1 CANONICAL=A0A3L7I3P3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I3P3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3P3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I3P3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3P3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:103162160", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103162160", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5NUT3-1", "protein_name": "Fibrinogen silencer binding protein", "gene_name": "FSBP", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVGKARSSNFTLSEKLDLLKLVKPYVKILEEHTNKHSVIVEKNKCWDIIADNYNAIGVDRPPRTAQGLRTLYKRLKEYAKQELLQQKETHSDCKSSISEPTKKVVEMIPQISNVCLRDRSGAQSASIDKETIAGTSSPQAVLDHHPATVMMKLQLEEDVKPPPSLIIDSQPSENVEQEEEHQLVHVMERSPSTSVSSVDMRVMMSPSPVPRRDEFFRLEVGERFRPMCGYDPQMLQMLKEEHQIMLENQRKIGLYVQEKRDGLKRKQQLEEELLRTKIKVEKLKAIRLRRDLPEYSII", "length": 298 }, "evidence": [ { "id": "A0A3L7I3P3", "url": "https://omabrowser.org/oma/group/A0A3L7I3P3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A287AE18-1", "protein_name": "DNA repair and recombination protein RAD54B", "gene_name": "RAD54B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRSAAPSQLQGNPLKKPRFIPPARSDPGLNEEKKLNSDVKLFEVPANKNAFLQSQNDPRICSFNLPPEESAREINREDNYREKYHLEASAKTTLDPHHTAHSAPKEVMVSNGQEEEPDSLVKYFSVVWCKASKKKHKKWEGDAVLIVKGKSFALKDLEGKDIGRGIGYKFKELEKIEEGQTMMIGGKEIEVMGVISPDDFSSGRCFQLGLSGALNSSQTPKKCTSNPFKSVCKLSSKENRQNGFQNCKPRHDPYAPNSLVMLRPDNNHQWMFNKNHFPIVDVVIDPHLVYHLRPHQREGIIFLYECVMGMRVNGRCGAILADEMGLGKTLQCISLIWTLQCQGPYGGKPVIKKTLIVTPGSLVNNWRKEFQKWLGSERIKIFTVDPDHKVEEFTKSPLYSVLIISYEMLLRSLDQIKNIKFDLLICDEGHRLKNSAIKTTTALFSLPCEKRIILTGTPVQNDLQEFFSLIDFVNPGILGSLSCYRKIYEEPIITSRQPSASQEEKELGERRACELTCLTGLFILRRTQEVINKYLPPKIENVVFCRPGALQIELYRKLLNSQAVRFCLQGLMENSSHLICIGALKKLCNHPCLLFSSVKEKECSSAWDENEERRLYEDLLKVFPPDYNPLMFAEEESGKLQVLSKLLAVIHELRPAEKVVLVSNYTQTLNILQEVCRRHGYGCTRLDGQTPISQRQQIVDGFNSKYSSDFIFLLSSKAGGVGLNLIGGSHLILYDIDWNPATDIQAMSRVWRDGQKHPVHIYRLLTTGTIEEKIYQRQISKQDLSGAVVDLTKTSDHIQFSVEELKNLFTLHENSHCVTHDLLDCECTGENHPGDSLEKFPLSRTCQLGPHQQKSNSLKPLSMSQLKQWKHFSGDHLNLSDPFLERIRGNVSFFFQNITNQTTAT", "length": 906 }, "evidence": [ { "id": "A0A3L7I3P3", "url": "https://omabrowser.org/oma/group/A0A3L7I3P3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABI0P3K7-1", "protein_name": "Fibrinogen silencer binding protein", "gene_name": "FSBP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVGKARSSNFTLSEKLDLLKLVKPYVKILEEHTNKHSVIVEKNRCWDIIAVNYNAIGVDRPPRTAQGLRTLYKRLKEYAKQELLQQKETQSDFKSNISEPTKKVMEMIPQISSFCLVRDRNHIQSANLDEEAQAGTSSLQVMLDRHPVAITVEVKQEEDIKPPLPLVLNSQQSDTLEQREEQELVRVMERSLSPSLSSVDMRMTSSPSSIPRRDDFFRHESGENFRSQLGYDPQILQMLKEEHQIILENQKSFGLYVQEKRDGLKRRQQLEEELLRAKIEVEKLKAIRLRHDLPEYNSL", "length": 299 }, "evidence": [ { "id": "A0A3L7I3P3", "url": "https://omabrowser.org/oma/group/A0A3L7I3P3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O95073-1", "protein_name": "Fibrinogen silencer-binding protein", "gene_name": "FSBP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVGKARSSNFTLSEKLDLLKLVKPYVKILEEHTNKHSVIVEKNRCWDIIAVNYNAIGVDRPPRTAQGLRTLYKRLKEYAKQELLQQKETQSDFKSNISEPTKKVMEMIPQISSFCLVRDRNHIQSANLDEEAQAGTSSLQVMLDHHPVAITVEVKQEEDIKPPPPLVLNSQQSDTLEQREEHELVHVMERSLSPSLSSVDMRMTSSPSSIPRRDDFFRHESGEHFRSLLGYDPQILQMLKEEHQIILENQKNFGLYVQEKRDGLKRRQQLEEELLRAKIEVEKLKAIRLRHDLPEYNSL", "length": 299 }, "evidence": [ { "id": "A0A3L7I3P3", "url": "https://omabrowser.org/oma/group/A0A3L7I3P3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BKE5-1", "protein_name": "Fibrinogen silencer-binding protein", "gene_name": "Fsbp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVGKARSSNFTLSEKLDLLNLVKPYVKILEEHTNKNSVIVEKNRCWDVIAVNYNAIGVDRPPRTAQGLRSLYKRLKEYAKQELLQQKEAQSEFKSSVSEPTKQVMEMIPQIASFGLIRDRSHIQSANLDETAQAGTSSLQVMVDHHPVAITVEVKQEEDIKPSPPLVSNPQLSDTLEQREEHELMHVVEGSESPSLSSVDMRMTSSPSSVPRRDEIFHQESGEHFRSLLRCDPQVLQMLKEEHQIILENQKNFGLYVQEKRDGLRRRQRLEEELLRAKIEVEKLKATRLRRDLPEYSSL", "length": 299 }, "evidence": [ { "id": "A0A3L7I3P3", "url": "https://omabrowser.org/oma/group/A0A3L7I3P3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I3P3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3P3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I3P3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3P3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 173, "end_pos": 175, "annotation": "n_glycosylation_sequon" }, { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3L7I3P3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3P3" }, { "id": "PF13873", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13873" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myb/SANT-like DNA-binding", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 85, "start_aa": "Arg", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 173, "end_pos": 175 }, { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7I3S0-1", "uniprot_ac": "A0A3L7I3S0", "uniprot_id": "A0A3L7I3S0_CRIGR", "mass": { "chemical_mass": 17659.0, "monoisotopic_mass": 17659.0 }, "refseq": { "ac": "XP_027260096", "name": "transcription factor BTF3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260096" }, "gene_names": [ { "name": "LOC100764179", "type": "recommended", "evidence": [ { "id": "A0A3L7I3S0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3S0" } ] }, { "name": "LOC100764179", "type": "synonym", "evidence": [ { "id": "XP_027260096", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260096" } ] } ], "protein_names": [ { "name": "Transcription factor BTF3", "type": "recommended", "evidence": [ { "id": "A0A3L7I3S0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3S0/entry#names_and_taxonomy" } ] }, { "name": "transcription factor BTF3", "type": "synonym", "evidence": [ { "id": "XP_027260096", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260096" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027260096", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260096" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I3S0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3S0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100764179", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3S0", "locus": {} } ], "crossref": [ { "id": "cd22055", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22055", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100764179", "url": "https://www.ncbi.nlm.nih.gov/gene/100764179", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764179", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764179", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3L7I3S0", "url": "https://www.orthodb.org/?gene=A0A3L7I3S0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10351", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10351", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01849", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01849", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027260096", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027260096", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7I3S0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3S0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7I3S0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3S0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKETIMNQEKLAKLQAQVRIGGKGTACRKKKVVHRTATADDKKLQFSLKKLGVNNISGVEEVNMFTNQGTVIYFNNPKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLAEALPKQSVDGKGPLATGEDDDDEVLDLVENFDEASKNEAI", "length": 162, "header": "tr|A0A3L7I3S0-1|A0A3L7I3S0_CRIGR Isoform 1 of Transcription factor BTF3 OS=Cricetulus griseus OX=10029 GN=LOC100764179 PE=3 SV=1 CANONICAL=A0A3L7I3S0-1" }, "isoforms": [ { "isoform_ac": "A0A3L7I3S0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I3S0/entry#A0A3L7I3S0-1", "sequence": { "sequence": "MKETIMNQEKLAKLQAQVRIGGKGTACRKKKVVHRTATADDKKLQFSLKKLGVNNISGVEEVNMFTNQGTVIYFNNPKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLAEALPKQSVDGKGPLATGEDDDDEVLDLVENFDEASKNEAI", "length": 162, "header": "tr|A0A3L7I3S0-1|A0A3L7I3S0_CRIGR Isoform 1 of Transcription factor BTF3 OS=Cricetulus griseus OX=10029 GN=LOC100764179 PE=3 SV=1 CANONICAL=A0A3L7I3S0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035294978", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294978" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I4E8", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100770571", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E8", "locus": {} } ], "crossref": [ { "id": "100770571", "url": "https://www.ncbi.nlm.nih.gov/gene/100770571", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770571", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770571", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WTRCCLS", "url": "https://omabrowser.org/oma/group/WTRCCLS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7I4E8", "url": "https://www.orthodb.org/?gene=A0A3L7I4E8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11783", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11783", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00685", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035294978", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294978", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7I4E8", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7I4E8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDNKREFLLNFKGYNFERSLVKMDIVENMDKHEIRDDDVFLVTYPKSGTVWTQQILSLIYFDGHRNGTENVSTIDRAPFFEYNNHNLDFAKIPSPRIFASHLPYYLAPKGLKKKKAKILYVYRNPKDVLTSYFHFSNLMTILQAADSIEVFMQTFLDGNVVGSRWFDHIKGWYEHRHDFNIMFQSYEDMKKDLRSSVLKICSFLEKELSEDDVDAVVRQATFQNMKSDPRANYEDVKTEIGARNDGGFLRKGTIGDWKRHLTVEQNERFDMIFYKNMKNFPLKFIWDINEE", "length": 291, "header": "tr|A0A3L7I4E8-1|A0A3L7I4E8_CRIGR Isoform 1 of Sulfotransferase OS=Cricetulus griseus OX=10029 GN=LOC100770571 PE=3 SV=1 CANONICAL=A0A3L7I4E8-1" }, "isoforms": [ { "isoform_ac": "A0A3L7I4E8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4E8/entry#A0A3L7I4E8-1", "sequence": { "sequence": "MDNKREFLLNFKGYNFERSLVKMDIVENMDKHEIRDDDVFLVTYPKSGTVWTQQILSLIYFDGHRNGTENVSTIDRAPFFEYNNHNLDFAKIPSPRIFASHLPYYLAPKGLKKKKAKILYVYRNPKDVLTSYFHFSNLMTILQAADSIEVFMQTFLDGNVVGSRWFDHIKGWYEHRHDFNIMFQSYEDMKKDLRSSVLKICSFLEKELSEDDVDAVVRQATFQNMKSDPRANYEDVKTEIGARNDGGFLRKGTIGDWKRHLTVEQNERFDMIFYKNMKNFPLKFIWDINEE", "length": 291, "header": "tr|A0A3L7I4E8-1|A0A3L7I4E8_CRIGR Isoform 1 of Sulfotransferase OS=Cricetulus griseus OX=10029 GN=LOC100770571 PE=3 SV=1 CANONICAL=A0A3L7I4E8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7I4F7-1", "uniprot_ac": "A0A3L7I4F7", "uniprot_id": "A0A3L7I4F7_CRIGR", "mass": { "chemical_mass": 35399.0, "monoisotopic_mass": 35399.0 }, "refseq": { "ac": "XP_003510372", "name": "calcium homeostasis modulator protein 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510372" }, "gene_names": [ { "name": "Calhm4", "type": "recommended", "evidence": [ { "id": "A0A3L7I4F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4F7" } ] }, { "name": "Calhm4", "type": "synonym", "evidence": [ { "id": "XP_003510372", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510372" } ] } ], "protein_names": [ { "name": "Calcium homeostasis modulator protein 4", "type": "synonym", "evidence": [ { "id": "A0A3L7I4F7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4F7/entry#names_and_taxonomy" } ] }, { "name": "calcium homeostasis modulator protein 4", "type": "synonym", "evidence": [ { "id": "XP_003510372", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510372" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614863.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003510372", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510372" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I4F7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4F7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Calhm4", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4F7", "locus": {} } ], "crossref": [ { "id": "100770005", "url": "https://www.ncbi.nlm.nih.gov/gene/100770005", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770005", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770005", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FRCPCQV", "url": "https://omabrowser.org/oma/group/FRCPCQV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7I4F7", "url": "https://www.orthodb.org/?gene=A0A3L7I4F7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32261", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32261", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32261:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32261:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14798", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14798", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003510372", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510372", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7I4F7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4F7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7I4F7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4F7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSPTLNCLLSSLQRSGTCTNSLIAILTICGQQLFSSYTFSCPCQVGKNFYYGSAFLVVPALILLIAGYALRGQMWTTVSEYCCCSCTPPYRRSSPLERRLACLMFFNITGRALVAPLTWLTVTLMTGTYYECAASEFASVDQYPMFANVTASKREEILAGFPCYTSAPSDVIPVRDEVALLHRYQSQMLAWILIILATIALLISNCLARCCSPLTSMQHHYWTNHLQSERALFEQAAEEHSRLLIRHRIKKVFGFLPGSEDIKHIRIPSCQDWRDISIPNILCVGDTSQGPYSFLGDRVVEENEEERQEGIELKP", "length": 315, "header": "tr|A0A3L7I4F7-1|A0A3L7I4F7_CRIGR Isoform 1 of Calcium homeostasis modulator protein 4 OS=Cricetulus griseus OX=10029 GN=Calhm4 PE=3 SV=1 CANONICAL=A0A3L7I4F7-1" }, "isoforms": [ { "isoform_ac": "A0A3L7I4F7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4F7/entry#A0A3L7I4F7-1", "sequence": { "sequence": "MSPTLNCLLSSLQRSGTCTNSLIAILTICGQQLFSSYTFSCPCQVGKNFYYGSAFLVVPALILLIAGYALRGQMWTTVSEYCCCSCTPPYRRSSPLERRLACLMFFNITGRALVAPLTWLTVTLMTGTYYECAASEFASVDQYPMFANVTASKREEILAGFPCYTSAPSDVIPVRDEVALLHRYQSQMLAWILIILATIALLISNCLARCCSPLTSMQHHYWTNHLQSERALFEQAAEEHSRLLIRHRIKKVFGFLPGSEDIKHIRIPSCQDWRDISIPNILCVGDTSQGPYSFLGDRVVEENEEERQEGIELKP", "length": 315, "header": "tr|A0A3L7I4F7-1|A0A3L7I4F7_CRIGR Isoform 1 of Calcium homeostasis modulator protein 4 OS=Cricetulus griseus OX=10029 GN=Calhm4 PE=3 SV=1 CANONICAL=A0A3L7I4F7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I4F7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4F7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I4F7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4F7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770005", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770005", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PP02-1", "protein_name": "Calcium homeostasis modulator family member 4", "gene_name": "FAM26D", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTFLPKWLTFLKGKEVVIANAIIAILTIGGQQLFSFFTFSCPCRVGQNLIYGLAFLGVPALILLVIGYALNNQTWRLVTGKRSPLLAESTWNQLLQCKLTCFVLCSITGRALVAPVTWLAVTLINGSYYVCAVSEYVSGYYYGDIPNVTISERQRILAAFPCSQLVPPELSRARDEVILLLRYQSQVAGWLVIAVVVITVFLSYCLASCFSPLSFLHFRYWTSYVRNEQELFDEATDQHSKLYAMKHVKKFFGFVPGNENINEIRIPSLREWQAISGLAFLKLVDEEHYDYSLLHDWALKDSADRKYLKLDEDP", "length": 314 }, "evidence": [ { "id": "A0A3L7I4F7", "url": "https://omabrowser.org/oma/group/A0A3L7I4F7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A4X1V2M0-1", "protein_name": "Calcium homeostasis modulator family member 4", "gene_name": "CALHM4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSPTLSNIISSLQRSGTFINSLIAALTIGGQQLFSSFTFSCPCQVGKNFYYGSAFLVIPALILLVAGFALRSQTWTITSEYCCSCFPPPRRISRLERKLACLQFFSITGRALVAPLTWLAVTLLTGTYYECAASEFTSVDHYPALDNLSASKREEILAGFPCCKPAPPDLVVIRDEVALLHRYQSQMLGWILIALATITVLISCSLARCCSPLTALQHRYWTNHLHNEQELFEQAAAQHSRLLIMQRIKKLFGFIPGNEDVTRIRIPSCQDWRDISVPSFLCVGDDLQGHYSFLGNRVDEENEESRSGGIELKP", "length": 314 }, "evidence": [ { "id": "A0A3L7I4F7", "url": "https://omabrowser.org/oma/group/A0A3L7I4F7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZDN4-1", "protein_name": "Calcium homeostasis modulator family member 4", "gene_name": "Calhm4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPDLNCIPSSLLRSEPCINSLIAILTVCGQQLFSSYTFSCPCQVGKNFYYGSAFLVVPALILLIAGYALRGQMWAVASEYCCCSCTPPYRRSSPLERRLACLMFFNITGRALVAPLTWLTVTLLTGTYYECAASEFASVDQYPMFANFTPSKREEMLAGFPCYTSAPSDVIPIRDEVALLHRYQSQMLGWILVVLATIAHLVSKCLARCCSPLTSLQHHYWANHLHNERMLFKQAAEEHSRLLIRHRIKKVFGFIPGSEDVKHIRIPSCQDWREISVPNLLCVGDTSQGPYSFLGDRVVEENEEDRQEGIELKP", "length": 315 }, "evidence": [ { "id": "A0A3L7I4F7", "url": "https://omabrowser.org/oma/group/A0A3L7I4F7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5JW98-1", "protein_name": "Calcium homeostasis modulator protein 4", "gene_name": "CALHM4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCPTLNNIVSSLQRNGIFINSLIAALTIGGQQLFSSSTFSCPCQVGKNFYYGSAFLVIPALILLVAGFALRSQMWTITGEYCCSCAPPYRRISPLECKLACLRFFSITGRAVIAPLTWLAVTLLTGTYYECAASEFASVDHYPMFDNVSASKREEILAGFPCCRSAPSDVILVRDEIALLHRYQSQMLGWILITLATIAALVSCCVAKCCSPLTSLQHCYWTSHLQNERELFEQAAEQHSRLLMMHRIKKLFGFIPGSEDVKHIRIPSCQDWKDISVPTLLCMGDDLQGHYSFLGNRVDEDNEEDRSRGIELKP", "length": 314 }, "evidence": [ { "id": "A0A3L7I4F7", "url": "https://omabrowser.org/oma/group/A0A3L7I4F7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CE93-1", "protein_name": "Calcium homeostasis modulator protein 4", "gene_name": "Calhm4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSPDLNCISSSLLRSEPCINSLIAILTVCGQQLFSSYTFSCPCQVGKNFYYGSAFLVVPALILLIAGYALRGQMWTVASEYCCCSCTPPYRRSSPLERRLACLMFFDITGRALVAPLTWLTVTLLTGTYYECAASEFASVDQYPMFANVTPSKREEMLAGFPCYTSAPSDVIPIRDEVALLHRYQSQMLGWILVVLATIALLLSKCLARCCSPLTSLQHHYWTNHLHNERVLFEKAAEEHSQLLIRHRIKKVFGFVPGSEDIKHIRIPSCQDWREISVPNLLCVGDTSQGPYSFLGDRVVEENEEDRQEGIEMKP", "length": 315 }, "evidence": [ { "id": "A0A3L7I4F7", "url": "https://omabrowser.org/oma/group/A0A3L7I4F7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I4F7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4F7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "monoatomic cation channel activity", "id": "GO:0005261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005261", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I4F7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4F7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ATP export", "id": "GO:1904669", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904669", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I4F7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4F7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 107, "end_pos": 109 }, { "start_pos": 148, "end_pos": 150 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7I4V7-1", "uniprot_ac": "A0A3L7I4V7", "uniprot_id": "A0A3L7I4V7_CRIGR", "mass": { "chemical_mass": 32958.0, "monoisotopic_mass": 32958.0 }, "refseq": { "ac": "XP_003505035", "name": "tropomyosin beta chain isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505035" }, "gene_names": [ { "name": "Tpm2", "type": "recommended", "evidence": [ { "id": "A0A3L7I4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4V7" } ] }, { "name": "Tpm2", "type": "synonym", "evidence": [ { "id": "XP_003505035", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505035" } ] } ], "protein_names": [ { "name": "Tropomyosin beta chain isoform X5", "type": "synonym", "evidence": [ { "id": "A0A3L7I4V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4V7/entry#names_and_taxonomy" } ] }, { "name": "tropomyosin beta chain isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003505035", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505035" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 222 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614108.1) and transcript sequence (JP056546.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 27, 2016 this sequence version replaced XP_003505035.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003505035", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505035" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I4V7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4V7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tpm2", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4V7", "locus": {} } ], "crossref": [ { "id": "100773233", "url": "https://www.ncbi.nlm.nih.gov/gene/100773233", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000533", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000533", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773233", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773233", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3L7I4V7", "url": "https://www.orthodb.org/?gene=A0A3L7I4V7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LK01", "url": "https://www.orthodb.org/?gene=A0A8C2LK01", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19269", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19269", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00261", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00261", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003505035", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505035", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7I4V7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4V7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7I4V7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4V7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LHJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LHJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LK01", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK01", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LK01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK01-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FHA4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FHA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FHA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FHA4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKDAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLIASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL", "length": 284, "header": "tr|A0A3L7I4V7-1|A0A3L7I4V7_CRIGR Isoform 1 of Tropomyosin beta chain isoform X5 OS=Cricetulus griseus OX=10029 GN=Tpm2 PE=3 SV=1 CANONICAL=A0A3L7I4V7-1" }, "isoforms": [ { "isoform_ac": "A0A3L7I4V7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4V7/entry#A0A3L7I4V7-1", "sequence": { "sequence": "MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKDAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLIASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL", "length": 284, "header": "tr|A0A3L7I4V7-1|A0A3L7I4V7_CRIGR Isoform 1 of Tropomyosin beta chain isoform X5 OS=Cricetulus griseus OX=10029 GN=Tpm2 PE=3 SV=1 CANONICAL=A0A3L7I4V7-1" }, "locus": {} }, { "isoform_ac": "A0A8C2LHJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4V7/entry#A0A8C2LHJ6-1", "sequence": { "sequence": "MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKDAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDITSL", "length": 284, "header": "tr|A0A8C2LHJ6-1|A0A8C2LHJ6_CRIGR Computationally mapped isoform of Tropomyosin beta chain isoform X7 OS=Cricetulus griseus OX=10029 GN=Tpm2 PE=3 SV=1 CANONICAL=A0A3L7I4V7-1" }, "locus": {} }, { "isoform_ac": "A0A8C2LK01-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4V7/entry#A0A8C2LK01-1", "sequence": { "sequence": "MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKDAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLIASEEEYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNALNDITSL", "length": 284, "header": "tr|A0A8C2LK01-1|A0A8C2LK01_CRIGR Computationally mapped isoform of Tropomyosin beta chain isoform X8 OS=Cricetulus griseus OX=10029 GN=Tpm2 PE=3 SV=1 CANONICAL=A0A3L7I4V7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FHA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4V7/entry#A0A9J7FHA4-1", "sequence": { "sequence": "MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKDAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEERAEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLELNNL", "length": 284, "header": "tr|A0A9J7FHA4-1|A0A9J7FHA4_CRIGR Computationally mapped isoform of Tropomyosin beta chain isoform X6 OS=Cricetulus griseus OX=10029 GN=Tpm2 PE=3 SV=1 CANONICAL=A0A3L7I4V7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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[ { "database": "UniProtKB", "id": "A0A3L7I4V7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I4V7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7I554-1", "uniprot_ac": "A0A3L7I554", "uniprot_id": "A0A3L7I554_CRIGR", "mass": { "chemical_mass": 17209.0, "monoisotopic_mass": 17209.0 }, "refseq": { "ac": "XP_027257908", "name": "protein FAM162B isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257908" }, "gene_names": [ { "name": "Fam162b", "type": "recommended", "evidence": [ { "id": "A0A3L7I554", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I554" } ] }, { "name": "Fam162b", "type": "synonym", "evidence": [ { "id": "XP_027257908", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257908" } ] } ], "protein_names": [ { "name": "Protein FAM162B isoform X2", "type": "synonym", "evidence": [ { "id": "A0A3L7I554", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I554/entry#names_and_taxonomy" } ] }, { "name": "protein FAM162B isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027257908", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257908" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027257908", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257908" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I554", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I554" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Fam162b", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I554", "locus": {} } ], "crossref": [ { "id": "100773450", "url": "https://www.ncbi.nlm.nih.gov/gene/100773450", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009432", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009432", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773450", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773450", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3L7I554", "url": "https://www.orthodb.org/?gene=A0A3L7I554", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13674", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13674", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13674:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13674:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06388", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06388", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027257908", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257908", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7I554", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I554", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7I554-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I554-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLWVLRWGLEFAVRRSPQTVSSWMGWGPRAAGHPRSSSSQNPSGSEPPEKIHKIPAQYKPSQFDKKILLWTGRFKSIDEIPSLVPPEMIDVARNKARVKTCYIMIGLTIIACFAVIVSAKRAVERHESLTSWNLAKKAKWREEAALAAQAKAK", "length": 153, "header": "tr|A0A3L7I554-1|A0A3L7I554_CRIGR Isoform 1 of Protein FAM162B isoform X2 OS=Cricetulus griseus OX=10029 GN=Fam162b PE=3 SV=1 CANONICAL=A0A3L7I554-1" }, "isoforms": [ { "isoform_ac": "A0A3L7I554-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I554/entry#A0A3L7I554-1", "sequence": { "sequence": "MLWVLRWGLEFAVRRSPQTVSSWMGWGPRAAGHPRSSSSQNPSGSEPPEKIHKIPAQYKPSQFDKKILLWTGRFKSIDEIPSLVPPEMIDVARNKARVKTCYIMIGLTIIACFAVIVSAKRAVERHESLTSWNLAKKAKWREEAALAAQAKAK", "length": 153, "header": "tr|A0A3L7I554-1|A0A3L7I554_CRIGR Isoform 1 of Protein FAM162B isoform X2 OS=Cricetulus griseus OX=10029 GN=Fam162b PE=3 SV=1 CANONICAL=A0A3L7I554-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I554", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I554" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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OS=Cricetulus griseus OX=10029 GN=Tmem268 PE=4 SV=1 CANONICAL=A0A3L7I7B1-1" }, "isoforms": [ { "isoform_ac": "A0A3L7I7B1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I7B1/entry#A0A3L7I7B1-1", "sequence": { "sequence": "MACEPPTDPGGAAGPLPTSILGCSTLPQRSPPGWGQELHNGQVLTVLRIDNTCAPISFDLGAVEEQLQAWGIQVPAEQYRNLAESALLEPQVRRYIIYNSRPMRLAFAVVFYVVVWANIYSTSQMFALGNQWAGVLLATLTAVSLTLTLVLVFERQQRKANTNTDLRLVATNGALLRHRVLLGMTDSVEGCQSVIQLWFVYFDLENCVQFLSDHVQEMKRSQESLLKSRLSQLCVVMETGVSTVVEGPEDLEDAPLLPSTPGHQERPLMQTELYQLVPDAEPEEMARQLLAVFGGYYTRLLVTSQLPQPMGTRHTDSARVPCPCQLIEAHILGTGCCPFLAR", "length": 342, "header": "tr|A0A3L7I7B1-1|A0A3L7I7B1_CRIGR Isoform 1 of Transmembrane protein 268 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tmem268 PE=4 SV=1 CANONICAL=A0A3L7I7B1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FFF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I7B1/entry#A0A9J7FFF2-1", "sequence": { "sequence": "MACEPPTDPGGAAGPLPTSILGCSTLPQRSPPGWGQELHNGQVLTVLRIDNTCAPISFDLGAVEEQLQAWGIQVPAEQYRNLAESALLEPQVRRYIIYNSRPMRLAFAVVFYVVVWANIYSTSQMFALGNQWAGVLLATLTAVSLTLTLVLVFERQQRKLWFVYFDLENCVQFLSDHVQEMKRSQESLLKSRLSQLCVVMETGVSTVVEGPEDLEDAPLLPSTPGHQERPLMQTELYQLVPDAEPEEMARQLLAVFGGYYTRLLVTSQLPQPMGTRHTDSARVPCPCQLIEAHILGTGCCPFLAR", "length": 305, "header": "tr|A0A9J7FFF2-1|A0A9J7FFF2_CRIGR Computationally mapped isoform of Transmembrane protein 268 isoform X2 OS=Cricetulus griseus OX=10029 GN=Tmem268 PE=4 SV=1 CANONICAL=A0A3L7I7B1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 7, "start_aa": "Thr", "end_pos": 7, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr7", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7I7F4-1", "uniprot_ac": "A0A3L7I7F4", "uniprot_id": "A0A3L7I7F4_CRIGR", "mass": { "chemical_mass": 106820.0, "monoisotopic_mass": 106820.0 }, "refseq": { "ac": "XP_027256561", "name": "proline-rich basic protein 1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256561" }, "gene_names": [ { "name": "LOC113834032", "type": "recommended", "evidence": [ { "id": "A0A3L7I7F4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I7F4" } ] }, { "name": "LOC113834032", "type": "synonym", "evidence": [ { "id": "XP_027256561", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256561" } ] } ], "protein_names": [ { "name": "Proline-rich basic protein 1-like", "type": "synonym", "evidence": [ { "id": "A0A3L7I7F4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I7F4/entry#names_and_taxonomy" } ] }, { "name": "proline-rich basic protein 1-like", "type": "synonym", "evidence": [ { "id": "XP_027256561", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256561" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027256561", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256561" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I7F4", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I7F4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113834032", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I7F4", "locus": {} } ], "crossref": [ { "id": "113834032", "url": "https://www.ncbi.nlm.nih.gov/gene/113834032", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027838", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027838", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052303", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052303", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113834032", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113834032", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3L7I7F4", "url": "https://www.orthodb.org/?gene=A0A3L7I7F4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33775", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33775", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33775:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33775:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15232", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15232", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027256561", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256561", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7I7F4", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I7F4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7I7F4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I7F4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLTALAPPALRGLSRRLPAPARRQDSSGSSGSYHTAPGSPEPPDVGPDTEGQGTWLWVAPGRGAGTQPVLSVSAQNSRQQRCSGSGFPRAPGSGPQPPRPQLRMLPSGEMEVIFGAGPLLSRSVAEGLEEQQLLAPAFSSPLPPRSAASPVSVSPQPQAPNRGSRWATYLELPARGRSPAVSGQYECVEVALEERTAPVRPRTVPKRQIELRPRPRSPSQDGRAPRPRLLLRTGSLDESLSRLQAAAGIVQTALAKKLGSAAPAPGNATFRPTGKPEPRASPPETARGTRVVPEEAKSRPPRPHDSSVPARAPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQQAHQQESKTQFLCETPDRTVPRARSPPSHSRSSRVAPSRVVRPRSPSPPRQARCPSPQNLSRPPRTVWKVSGSSCPEASSEWENRSAAVEEVLSRRSPSPPPLSQWTRGVAGVGNPCPESPSRWKVPHSIGGDATGLSRDPALIALLPRESSDHPIGTNSPSPREAPGPLVQGSSTVLGQEAMNGLTQELEAPTPPAPGTPELPEAQGLLTMENVDVAYRGRQPSPVADTPQPPGSHLTSVLEDDVCPEASASGEAASGRPRVTIPRPRDVRKMVKTTYAPSFPAGTPGCGLPAPLADTCCGEAGDASNAHELPALESPAPAHYTSIFLKDFLPVVPHPYEPPEPTLHATPKEVSHSSGVPKRRAENSTAKPFARSEIRLPGALALSRQREKTAGVQGSSPARQNPDAEASRRVPDLEGRTSPLGGARTSTQRFPSGSAGTQPPRPGSPQACPISSLGAAPELETPLVAPATVVQAPLPREPQVTAAGTAAPLPRAASAPPTERLPSASSQRMRRLPEASPPGKVLVDPESGRYYFVEAPRQPRLRLLFDPESGQYVEVLLPPSPSLSRPPRQAYTPLALGPGLYPPAYGPIPGSSLSPPSPNLPPLGSLQLPWAPEAGPLEGMYYMPLSGTPSPAPPMLFCAPPSSSGPIQSSKGSVFPL", "length": 1013, "header": "tr|A0A3L7I7F4-1|A0A3L7I7F4_CRIGR Isoform 1 of Proline-rich basic protein 1-like OS=Cricetulus griseus OX=10029 GN=LOC113834032 PE=4 SV=1 CANONICAL=A0A3L7I7F4-1" }, "isoforms": [ { "isoform_ac": "A0A3L7I7F4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I7F4/entry#A0A3L7I7F4-1", "sequence": { "sequence": "MLTALAPPALRGLSRRLPAPARRQDSSGSSGSYHTAPGSPEPPDVGPDTEGQGTWLWVAPGRGAGTQPVLSVSAQNSRQQRCSGSGFPRAPGSGPQPPRPQLRMLPSGEMEVIFGAGPLLSRSVAEGLEEQQLLAPAFSSPLPPRSAASPVSVSPQPQAPNRGSRWATYLELPARGRSPAVSGQYECVEVALEERTAPVRPRTVPKRQIELRPRPRSPSQDGRAPRPRLLLRTGSLDESLSRLQAAAGIVQTALAKKLGSAAPAPGNATFRPTGKPEPRASPPETARGTRVVPEEAKSRPPRPHDSSVPARAPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQQAHQQESKTQFLCETPDRTVPRARSPPSHSRSSRVAPSRVVRPRSPSPPRQARCPSPQNLSRPPRTVWKVSGSSCPEASSEWENRSAAVEEVLSRRSPSPPPLSQWTRGVAGVGNPCPESPSRWKVPHSIGGDATGLSRDPALIALLPRESSDHPIGTNSPSPREAPGPLVQGSSTVLGQEAMNGLTQELEAPTPPAPGTPELPEAQGLLTMENVDVAYRGRQPSPVADTPQPPGSHLTSVLEDDVCPEASASGEAASGRPRVTIPRPRDVRKMVKTTYAPSFPAGTPGCGLPAPLADTCCGEAGDASNAHELPALESPAPAHYTSIFLKDFLPVVPHPYEPPEPTLHATPKEVSHSSGVPKRRAENSTAKPFARSEIRLPGALALSRQREKTAGVQGSSPARQNPDAEASRRVPDLEGRTSPLGGARTSTQRFPSGSAGTQPPRPGSPQACPISSLGAAPELETPLVAPATVVQAPLPREPQVTAAGTAAPLPRAASAPPTERLPSASSQRMRRLPEASPPGKVLVDPESGRYYFVEAPRQPRLRLLFDPESGQYVEVLLPPSPSLSRPPRQAYTPLALGPGLYPPAYGPIPGSSLSPPSPNLPPLGSLQLPWAPEAGPLEGMYYMPLSGTPSPAPPMLFCAPPSSSGPIQSSKGSVFPL", "length": 1013, "header": "tr|A0A3L7I7F4-1|A0A3L7I7F4_CRIGR Isoform 1 of Proline-rich basic protein 1-like OS=Cricetulus griseus OX=10029 GN=LOC113834032 PE=4 SV=1 CANONICAL=A0A3L7I7F4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 546, "start_aa": "Thr", "end_pos": 546, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr546", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 984, "start_aa": "Thr", "end_pos": 984, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr984", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613906.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003502718", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502718" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I7Q6", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I7Q6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tmem269", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I7Q6", "locus": {} } ], "crossref": [ { "id": "100773888", "url": "https://www.ncbi.nlm.nih.gov/gene/100773888", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000462", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000462", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773888", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773888", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YKGLPCR", "url": "https://omabrowser.org/oma/group/YKGLPCR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7I7Q6", "url": "https://www.orthodb.org/?gene=A0A3L7I7Q6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF01066", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01066", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003502718", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502718", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7I7Q6", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I7Q6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7I7Q6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I7Q6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFGTGDLSLHSSCVPSRKKRRQGQHILNHENSISQMTTELSWKDVINALSLANMVLGLFSIFCSFSRKSHCASWMLLISFLLDMAVGTMTRHLNICHKMGLELNDFAVFTTFGLASALLLGVDGPLNGFLAVIYVLTTSFRLCFYSTGGGPSVYKGLPCPYASCVLASTCLLTKGNTFILCCMASLMILFMIDQSCYPHDEVLESENWKKVVYMGGIIMLFLSPFSLTAFYCLIWSLSYIFFPDALWGRGACIKL", "length": 255, "header": "tr|A0A3L7I7Q6-1|A0A3L7I7Q6_CRIGR Isoform 1 of Transmembrane protein 269 OS=Cricetulus griseus OX=10029 GN=Tmem269 PE=4 SV=1 CANONICAL=A0A3L7I7Q6-1" }, "isoforms": [ { "isoform_ac": "A0A3L7I7Q6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I7Q6/entry#A0A3L7I7Q6-1", "sequence": { "sequence": "MFGTGDLSLHSSCVPSRKKRRQGQHILNHENSISQMTTELSWKDVINALSLANMVLGLFSIFCSFSRKSHCASWMLLISFLLDMAVGTMTRHLNICHKMGLELNDFAVFTTFGLASALLLGVDGPLNGFLAVIYVLTTSFRLCFYSTGGGPSVYKGLPCPYASCVLASTCLLTKGNTFILCCMASLMILFMIDQSCYPHDEVLESENWKKVVYMGGIIMLFLSPFSLTAFYCLIWSLSYIFFPDALWGRGACIKL", "length": 255, "header": "tr|A0A3L7I7Q6-1|A0A3L7I7Q6_CRIGR Isoform 1 of Transmembrane protein 269 OS=Cricetulus griseus OX=10029 GN=Tmem269 PE=4 SV=1 CANONICAL=A0A3L7I7Q6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I7Q6", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I7Q6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I7Q6", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I7Q6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773888", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773888", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1B0GVZ9-1", "protein_name": "Transmembrane protein 269", "gene_name": "TMEM269", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVLGLFSIIFSFSRKCHYASRMLLVSFLLDMAVRAMTSHINICSKLGAELNDFAVFTTFGLASALLLGVDGLLSGILAIIYVSAASFHLCFYSPGVPSTYKGLPCPYASCILASTSLLTKGNRFILCCMASLMILFMMDQSYYPYDKILESENWKKLVYIGGVIMLFFSPLSLSAFYCLMWSLSYIFFPDALWGKAACLSPQH", "length": 203 }, "evidence": [ { "id": "A0A3L7I7Q6", "url": "https://omabrowser.org/oma/group/A0A3L7I7Q6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A8V0YWH1-1", "protein_name": "cardiolipin synthase (CMP-forming)", "gene_name": "LOC100859906", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MWMVSPPVDEGSHQLAWLWDHGKGIFQYTKKLFLSRPVGRAQALEFIRKNAANALSMANLIVGLSSILSSLNRQYHCSCWLLLVGFLLDLADGAVARQLNACSALGAKLDDFADFTSFGLATALLLQPRGMLDGLLAIVYVLAVFARLCFFSSGIPFTYRGLPCPYASSLLASTFLLTGGHITLLRIAAIAMVLFMVDRGFYPHDKVLESQSWKKVIYAGGIVAVLFSPTTVAPIYYLAWSASYILLPFAIWSCKA", "length": 256 }, "evidence": [ { "id": "A0A3L7I7Q6", "url": "https://omabrowser.org/oma/group/A0A3L7I7Q6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ABK0LLB0-1", "protein_name": "Transmembrane protein 269", "gene_name": "Tmem269", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASGLRERMAMYAMRKDKRHHCWKVHLHSYQPLMLPGLMLGTRGSNLHPSCIPSRKKRRQGHRAMNQEQNSSQMTEFSWKDVINALSLANMILGLFSIFCSFSRKSHCASWMLLISFLLDIAIGTMTRHFNICHKQGLELNDFAVFTTFGLASALLLGVDGPLNGFLAIIYVLTTSFRLCFYSAGGGSSGYKGLPCPYASCVLASTCLLTKGNTFILCCMASLMILFMIDQSCYPHDEILDSDNWKKIVYIGGVILLFFSPFPLTAFYCLTWSLSYIFSPDTLWGRGVCIKL", "length": 292 }, "evidence": [ { "id": "A0A3L7I7Q6", "url": "https://omabrowser.org/oma/group/A0A3L7I7Q6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58IK54-1", "protein_name": "Transmembrane protein 269 isoform X1", "gene_name": "tmem269", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSLLSPNRAVWRAFGADLSVLLIGGRRGECSFASGTEITLFKSFLQEAKKLLLNEQANWAHLKEFARKNAANALSVANLLMGMASILCSLNGHHYAACWLVLIGYLLDLADGAVARHLNACSALGAKLDDFADFTTFGIATSLLLRTPSLLDNILCMLYMLSVFVRLCFFSSGIPFVYRGLPCIYSSAILVCGSLLTGGNMAVLRILAVAMILFMISQNFYPHDRVLESQAWKKVVYIGGVVMVFCSSFPPACVYYLLWSVSYILFPTTLWSCKV", "length": 275 }, "evidence": [ { "id": "A0A3L7I7Q6", "url": "https://omabrowser.org/oma/group/A0A3L7I7Q6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9D4Y8-1", "protein_name": "Transmembrane protein 269", "gene_name": "Tmem269", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLGTGDPNLHSSCILSRKKGRQGHHIMKHEQIGSQMTEFSWKDIINALALANMILGLFSIFCSFSRKSYCASWMLLISFLLDIAIGTMTKHLNIPHKLGLELNDFAIFTTFGLASALLLGVDGPLNGFLAIIYVLTTSFRMCFYSTGGATSGYKGLPCPYASCVLASTCLLTKGNTFILCCMASLMILFMIDQSCYPHDEILDSDNWKKIVYIGGVILLFFSPFPLTAFYCLTWSLSYIFSPETLWGRGVRIKP", "length": 254 }, "evidence": [ { "id": "A0A3L7I7Q6", "url": "https://omabrowser.org/oma/group/A0A3L7I7Q6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I7Q6", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I7Q6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "phospholipid biosynthetic process", "id": "GO:0008654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008654", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I7Q6", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I7Q6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphotransferase activity, for other substituted phosphate groups", "id": "GO:0016780", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016780", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I7Q6", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I7Q6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7I7Y7-1", "uniprot_ac": "A0A3L7I7Y7", "uniprot_id": "A0A3L7I7Y7_CRIGR", "mass": { "chemical_mass": 21811.0, "monoisotopic_mass": 21811.0 }, "refseq": { "ac": "XP_003502734", "name": "uncharacterized protein C1orf50 homolog isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502734" }, "gene_names": [ { "name": "LOC100754108", "type": "recommended", "evidence": [ { "id": "A0A3L7I7Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I7Y7" } ] }, { "name": "LOC100754108", "type": "synonym", "evidence": [ { "id": "XP_003502734", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502734" } ] } ], "protein_names": [ { "name": "Uncharacterized protein C1orf50 homolog isoform X4", "type": "synonym", "evidence": [ { "id": "A0A3L7I7Y7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I7Y7/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C1orf50 homolog isoform X3", "type": "synonym", "evidence": [ { "id": "XP_003502734", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502734" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 386 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613906.1) and transcript sequence (IACG01048451.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003502734.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003502734", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502734" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I7Y7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I7Y7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100754108", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I7Y7", "locus": {} } ], "crossref": [ { "id": "100754108", "url": "https://www.ncbi.nlm.nih.gov/gene/100754108", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019534", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019534", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754108", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754108", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3L7I7Y7", "url": "https://www.orthodb.org/?gene=A0A3L7I7Y7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14553", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14553", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14553:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14553:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10504", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10504", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003502734", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502734", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7I7Y7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I7Y7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7I7Y7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I7Y7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FCD4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FCD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FCD4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J8C8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8C8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J8C8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J8C8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEDPATPGPLEKGTASPGVQQAAGPGGALVELTPTPGGLALVSPYHTNRVGDPLDLVALAEQVQKADEFIRANATNKLTVIAEQIQHLQEQARKVLEDARRDADLHHVACNMVKKPGNIYYLYQRESGQQYFSIISPEEWGAGCPHDFLGAYKLQHDLSWTPYEDIEKQDAKIGMMDKLLNQPMALPPCTEPAFQGLTH", "length": 199, "header": "tr|A0A3L7I7Y7-1|A0A3L7I7Y7_CRIGR Isoform 1 of Uncharacterized protein C1orf50 homolog isoform X4 OS=Cricetulus griseus OX=10029 GN=LOC100754108 PE=4 SV=1 CANONICAL=A0A3L7I7Y7-1" }, "isoforms": [ { "isoform_ac": "A0A3L7I7Y7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I7Y7/entry#A0A3L7I7Y7-1", "sequence": { "sequence": "MEDPATPGPLEKGTASPGVQQAAGPGGALVELTPTPGGLALVSPYHTNRVGDPLDLVALAEQVQKADEFIRANATNKLTVIAEQIQHLQEQARKVLEDARRDADLHHVACNMVKKPGNIYYLYQRESGQQYFSIISPEEWGAGCPHDFLGAYKLQHDLSWTPYEDIEKQDAKIGMMDKLLNQPMALPPCTEPAFQGLTH", "length": 199, "header": "tr|A0A3L7I7Y7-1|A0A3L7I7Y7_CRIGR Isoform 1 of Uncharacterized protein C1orf50 homolog isoform X4 OS=Cricetulus griseus OX=10029 GN=LOC100754108 PE=4 SV=1 CANONICAL=A0A3L7I7Y7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FCD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I7Y7/entry#A0A9J7FCD4-1", "sequence": { "sequence": "MEDPATPGPLEKGALVELTPTPGGLALVSPYHTNRVGDPLDLVALAEQVQKADEFIRANATNKLTVIAEQIQHLQEQARKVLEDARRDADLHHVACNMVKKPGNIYYLYQRESGQQYFSIISPEEWGAGCPHDFLGAYKLQHDLSWTPYEDIEKQDAKIGMMDKLLNQPMALPPCTEPAFQGLTH", "length": 185, "header": "tr|A0A9J7FCD4-1|A0A9J7FCD4_CRIGR Computationally mapped isoform of Uncharacterized protein C1orf50 homolog isoform X5 OS=Cricetulus griseus OX=10029 GN=LOC100754108 PE=4 SV=1 CANONICAL=A0A3L7I7Y7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J8C8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I7Y7/entry#A0A9J7J8C8-1", "sequence": { "sequence": "MEDPATPGPLEKGTASPGVQQAAGPGGALVELTPTPGGLALVSPYHTNRVGDPLDLVALAEQVQKVLEDARRDADLHHVACNMVKKPGNIYYLYQRESGQQYFSIISPEEWGAGCPHDFLGAYKLQHDLSWTPYEDIEKQDAKIGMMDKLLNQPMALPPCTEPAFQGLTH", "length": 170, "header": "tr|A0A9J7J8C8-1|A0A9J7J8C8_CRIGR Computationally mapped isoform of Uncharacterized protein C1orf50 homolog isoform X6 OS=Cricetulus griseus OX=10029 GN=LOC100754108 PE=4 SV=1 CANONICAL=A0A3L7I7Y7-1" }, "locus": {} } ], "glycosylation": 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"", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NW_003613862.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003501863", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501863" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I819", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I819" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tmco2", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I819", "locus": {} } ], "crossref": [ { "id": "100752424", "url": "https://www.ncbi.nlm.nih.gov/gene/100752424", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031697", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031697", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752424", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752424", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WNWLQAT", "url": "https://omabrowser.org/oma/group/WNWLQAT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7I819", "url": "https://www.orthodb.org/?gene=A0A3L7I819", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR38496", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38496", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR38496:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38496:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15844", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15844", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003501863", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501863", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7I819", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I819", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7I819-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I819-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPKSPTATSSWDNLLNAIARSSIWNWLQATFVGETSAPQPTNLGIIDNLAPAVQVILGISFLVLLAIGLFALWKRSVRSIQKIVMFVITLYQLYKKGSDFFQALLANPEGNSRQMQDNSNIFLSLGLQEKILKKLQMVENKVRDLEGMIVAQKPAVKRDCSSEPYCSCSDCQSPLPTSGFTSTSEM", "length": 186, "header": "tr|A0A3L7I819-1|A0A3L7I819_CRIGR Isoform 1 of Transmembrane and coiled-coil domain-containing protein 2 OS=Cricetulus griseus OX=10029 GN=Tmco2 PE=4 SV=1 CANONICAL=A0A3L7I819-1" }, "isoforms": [ { "isoform_ac": "A0A3L7I819-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I819/entry#A0A3L7I819-1", "sequence": { "sequence": "MPKSPTATSSWDNLLNAIARSSIWNWLQATFVGETSAPQPTNLGIIDNLAPAVQVILGISFLVLLAIGLFALWKRSVRSIQKIVMFVITLYQLYKKGSDFFQALLANPEGNSRQMQDNSNIFLSLGLQEKILKKLQMVENKVRDLEGMIVAQKPAVKRDCSSEPYCSCSDCQSPLPTSGFTSTSEM", "length": 186, "header": "tr|A0A3L7I819-1|A0A3L7I819_CRIGR Isoform 1 of Transmembrane and coiled-coil domain-containing protein 2 OS=Cricetulus griseus OX=10029 GN=Tmco2 PE=4 SV=1 CANONICAL=A0A3L7I819-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"MSSSSSIWDIIIDYLSLSSIWNYLQATLLGETSVPQQTNLGPLDNLAPAVQVILGISFLILLGVGMYALWKRSVQSIQKILLFAITLYKLYKKGSDFFQALLVNPEGSDLTLQDNNIFLSLGLQEKILKKLQTVENKVKDLEGMIISQKPTTKREYSSDHYCSCSDCQSPLPTSGFTSTSEM", "length": 182 }, "evidence": [ { "id": "A0A3L7I819", "url": "https://omabrowser.org/oma/group/A0A3L7I819/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q7Z6W1-1", "protein_name": "Transmembrane and coiled-coil domain-containing protein 2", "gene_name": "TMCO2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSTSSSSSWDNLLESLSLSTVWNWIQASFLGETSAPQQTSLGLLDNLAPAVQIILRISFLILLGIGIYALWKRSIQSIQKTLLFVITLYKLYKKGSHIFEALLANPEGSGLRIQDNNNLFLSLGLQEKILKKLKTVENKMKNLEGIIVAQKPATKRDCSSEPYCSCSDCQSPLSTSGFTSPI", "length": 182 }, "evidence": [ { "id": "A0A3L7I819", "url": "https://omabrowser.org/oma/group/A0A3L7I819/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular 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pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614813.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003510065", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510065" } ] }, { "annotation": "May be involved in synaptic plasticity regulation through the control of Rac-GTP levels.", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I8M5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I8M5#function" }, { "database": "UniProtKB", "id": "ARBA00056636", "url": "https://www.uniprot.org/uniprotkb/ARBA00056636#function" }, { "database": "UniProtKB", "id": "A0A9J7GTC8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GTC8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I8M5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I8M5" } ], "common_name": "Chinese hamster", 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I8M5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I8M5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I8M5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I8M5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765078", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765078", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A096MJ64-1", "protein_name": "SH2 domain-containing protein 5", "gene_name": "Sh2d5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRAGAGARRASDCGPAPYRPRCIAKFAQYVGSFPVDDLDTQESVCLVQQHLWALQDCSRRRAVILKFSLQGLKIYSGEGEVLLMAHALKRILYATWNPAACQFAFVARNPRSPASKLFCHLFVGSQPGEINILYLLLCRSFQLAYLLQHPEERAQPEPSLVPGGDMSLKPLCSPGVAPALVREPFSRDQLSQNVHALVSFRRLPAEGLLGSNGKELPEPEGRGGTRHIRLGNPYCSPTLVRKKAIRSKVIRSGAYRGCTYETQLQLSAREAFPAAWEAWPRGPGSPSCLVENEGSLTENIWAFAGLSRSCALALLRRDVHGAFLLWPEPGTSGQWSLSVRTQCGVVSHQVFRNHLGRYCLEHLPAEFPSLEALVESHAGMERSLFCPLSMGRLNPTYEEQDSGPEGRFPRTLRPLSHAKSEAELQGLG", "length": 429 }, "evidence": [ { "id": "A0A3L7I8M5", "url": "https://omabrowser.org/oma/group/A0A3L7I8M5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0ZNL1-1", "protein_name": "SH2 domain containing 5", "gene_name": "SH2D5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKKKMTANGRGPDPAPPPPRARGIAKSAEYVGSFMVEELELQQHVGQLEEQLRALKDCPRRRSVVLRFSLQGLKVYGDDGETLLMAHALRRILYSTCLHAERQFAFVARNPHSPPSTLFCHLFVSPVGEVHVLHLLLCRSFQLCYLQAHPELQAAEPDPPVLLRETLNPEEVSRNVNALLSLRRLPALGPLGAGHVFAQHLLQERRVEAEGRAVGWRPGNPYCSPVLVRKKAIRSKVLRSGAYRDCGAESQLQQREGGIGFGALKEDPGGQERDLGPDTHPPPSAPSGWESRGMRGLVLLPDTEAALAESVWAFAGIARASGIALLRGDVPGAFLLRPEPGATPRWCLWVHTPCGVVPYCVLRTQQGRFCVEHSHAEFRSMPALLAHYSAVPGGCFCRLSVGRCNPGYEQRDEDGPALVQHERG", "length": 424 }, "evidence": [ { "id": "A0A3L7I8M5", "url": "https://omabrowser.org/oma/group/A0A3L7I8M5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E1BA40-1", "protein_name": "SH2 domain-containing protein 5", "gene_name": "SH2D5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQKAGAGGRRASDCGPAPQRPRCITKFAQYVGSFPVDDLDPQESVWLVQQQLWALKDCPRRRAVILKFSLQGLKIYSGEGEVLLMAHALRRILYATWCPADCQFAFMARNPRSPASKLFCHLFVGSQPGEVQILHLLLCRSFQLAYLLQHPEERARPEPCPEPVGDAPLKPVPGPGGPPGLVREPFGRDQLSQNVNALVSFRRLPAEGSGGSGKELLESASRGGTRHLRLGNPYCSPTLVRKKAIRSKVLRSGAYRACTYETQLQLSAREALPAAWEAWPRGPGGPSCLVESEGSLTENIWAFAGISRTSALALLRRDVLGAFLLWPEPGANGQWCLSVRTQCGVVPHQVFRNHVGRYCVEHLPAEFPSLEALVEHHAGTERSLFCSLDMGRLNPGYEEQDCGPSGQPPRTLRPLGHAKSEAELQGLG", "length": 428 }, "evidence": [ { "id": "A0A3L7I8M5", "url": "https://omabrowser.org/oma/group/A0A3L7I8M5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1Q5B0-1", "protein_name": "SH2 domain-containing protein 5 isoform 1", "gene_name": "sh2d5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": 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"glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7I907-1", "uniprot_ac": "A0A3L7I907", "uniprot_id": "A0A3L7I907_CRIGR", "mass": { "chemical_mass": 15083.0, "monoisotopic_mass": 15083.0 }, "refseq": { "ac": "XP_027254568", "name": "fatty acid-binding protein 5 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254568" }, "gene_names": [ { "name": "Fabp5", "type": "recommended", "evidence": [ { "id": "A0A3L7I907", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I907" } ] }, { "name": "Fabp5", "type": "synonym", "evidence": [ { "id": "XP_027254568", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254568" } ] } ], "protein_names": [ { "name": "Fatty acid-binding protein 5 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A3L7I907", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I907/entry#names_and_taxonomy" } ] }, { "name": "fatty acid-binding protein 5 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027254568", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254568" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027254568", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254568" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I907", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I907" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Fabp5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I907", "locus": {} } ], "crossref": [ { "id": "cd19468", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19468", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100762553", "url": "https://www.ncbi.nlm.nih.gov/gene/100762553", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000463", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000463", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000566", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000566", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012674", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012674", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762553", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762553", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3L7I907", "url": "https://www.orthodb.org/?gene=A0A3L7I907", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11955", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11955", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00061", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00061", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027254568", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254568", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7I907", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I907", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7I907-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I907-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASIKDLEGKWRLTESQGFEEYMKELGVGLALRKMGAMAKPDCIITCDGNNITIKTESTLKTTQFSCTLGEKFDETTADGRKTQTVCTFTDGALVQHQNWDGKESTITRRVKDGKLVVDCVMNNVTCTRVYEKVE", "length": 135, "header": "tr|A0A3L7I907-1|A0A3L7I907_CRIGR Isoform 1 of Fatty acid-binding protein 5 isoform X2 OS=Cricetulus griseus OX=10029 GN=Fabp5 PE=3 SV=1 CANONICAL=A0A3L7I907-1" }, "isoforms": [ { "isoform_ac": "A0A3L7I907-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I907/entry#A0A3L7I907-1", "sequence": { "sequence": "MASIKDLEGKWRLTESQGFEEYMKELGVGLALRKMGAMAKPDCIITCDGNNITIKTESTLKTTQFSCTLGEKFDETTADGRKTQTVCTFTDGALVQHQNWDGKESTITRRVKDGKLVVDCVMNNVTCTRVYEKVE", "length": 135, "header": "tr|A0A3L7I907-1|A0A3L7I907_CRIGR Isoform 1 of Fatty acid-binding protein 5 isoform X2 OS=Cricetulus griseus OX=10029 GN=Fabp5 PE=3 SV=1 CANONICAL=A0A3L7I907-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I907", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I907" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003514148", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514148" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I9F9", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I9F9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ccdc27", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I9F9", "locus": {} } ], "crossref": [ { "id": "100774639", "url": "https://www.ncbi.nlm.nih.gov/gene/100774639", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR052642", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052642", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060375", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060375", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774639", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774639", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DAQCPEW", "url": "https://omabrowser.org/oma/group/DAQCPEW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7I9F9", "url": "https://www.orthodb.org/?gene=A0A3L7I9F9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18853", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18853", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18853:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18853:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF28447", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28447", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003514148", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514148", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7I9F9", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I9F9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7I9F9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I9F9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKKENFPEELSLPTPQISKGLALLQSVSSRRSHGVENKQLEDQHRSSKSAQAINHYNSKVSQLKKLTNPDGFVSEMEEMRKAFLMRPGCPQFSTRATSVSHMGSATTVDMPRDNSGTWKMTEDQPLVGQDSDTSMDGRLFSISKSACELSFSRKRSEPPTTSPPGSPTMVKRSQRTRMPWYISVIHEKDHSLVRLEEELQRLSVLETQMQKKDQEILSLQKEKEALKKQLKILLRSKGTEASSASIRTERSFEAALKLGRLSMLRPVYREDEELQHWMQMQEDYNVVENRERPMEAGSITEEKGSEGPPEEAAKPRSLGSLSTRSIVKGGTLHEEGPEEEEEEELKGAEEEEEVVIGEEELWELKEEEEEEQRPRKSYSITESFEEELMAQLEEYERMLMDLQSELELTRAKYSLATGAITSLQRQTNFQESQLRKVTTENERLEKELRERKQQIQTMTNKFSNLREEKKQQGIMGLIEKENLALRQQVSDLETELLKRDQTITELHTKTSELQAHVDLNEDHLRRWKNLHDDLQRRNETIQQAEQQTRVVLESCQARLERLRNKIIQAVFSASGTKNLSTELSDSYILESLQRIITERSDFYGQLKQKGVKVPPLQQSDISLPTKIKKLSPK", "length": 633, "header": "tr|A0A3L7I9F9-1|A0A3L7I9F9_CRIGR Isoform 1 of Coiled-coil domain-containing protein 27 OS=Cricetulus griseus OX=10029 GN=Ccdc27 PE=4 SV=1 CANONICAL=A0A3L7I9F9-1" }, "isoforms": [ { "isoform_ac": "A0A3L7I9F9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I9F9/entry#A0A3L7I9F9-1", "sequence": { "sequence": "MKKENFPEELSLPTPQISKGLALLQSVSSRRSHGVENKQLEDQHRSSKSAQAINHYNSKVSQLKKLTNPDGFVSEMEEMRKAFLMRPGCPQFSTRATSVSHMGSATTVDMPRDNSGTWKMTEDQPLVGQDSDTSMDGRLFSISKSACELSFSRKRSEPPTTSPPGSPTMVKRSQRTRMPWYISVIHEKDHSLVRLEEELQRLSVLETQMQKKDQEILSLQKEKEALKKQLKILLRSKGTEASSASIRTERSFEAALKLGRLSMLRPVYREDEELQHWMQMQEDYNVVENRERPMEAGSITEEKGSEGPPEEAAKPRSLGSLSTRSIVKGGTLHEEGPEEEEEEELKGAEEEEEVVIGEEELWELKEEEEEEQRPRKSYSITESFEEELMAQLEEYERMLMDLQSELELTRAKYSLATGAITSLQRQTNFQESQLRKVTTENERLEKELRERKQQIQTMTNKFSNLREEKKQQGIMGLIEKENLALRQQVSDLETELLKRDQTITELHTKTSELQAHVDLNEDHLRRWKNLHDDLQRRNETIQQAEQQTRVVLESCQARLERLRNKIIQAVFSASGTKNLSTELSDSYILESLQRIITERSDFYGQLKQKGVKVPPLQQSDISLPTKIKKLSPK", "length": 633, "header": "tr|A0A3L7I9F9-1|A0A3L7I9F9_CRIGR Isoform 1 of Coiled-coil domain-containing protein 27 OS=Cricetulus griseus OX=10029 GN=Ccdc27 PE=4 SV=1 CANONICAL=A0A3L7I9F9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"MKQESLPQECSSTSPKINKGLMALQSIASRSWGVKNSEKKPQNTPQSLSKSTQAVGCFYCKEDQIKKFSKHNGFVSEMEDMRRAFLMRPGCPQFSTRTTSVSHVGSATMVDLPSPSSGVWKMSEDHPLCRLGSATSVDGKFFPSSRSACELNYPRKRSEPSVTSPIGSPTMVKKSQRTRMPWYISVIHEKDHSLLLMGEELQRFSEMETQMQKKDQEILMLQKEKEALRKQLRSLLRSKATEPSSAFIRMERSFETPLKLGRMSMLKTIYKEEDELQRWIQMQEEAESNKEPGSTIEEKSSEGQPEEAAPTKQRTSHSKTGTLLEVSPEEEEEETKGTEEDESTVDEEEGLWELREEEERRPKKSYSMTESFEEELMAQLEEYERMLMDFQNELELTRSKYSLATGAITSLQRHTDFQESQLRKVTTENELLVKELRERKQQIQDMTDKFSNLREEKKHQEIMGLIEKENLTLRQKVADLKTELENSEHTIEELNAQTKELENLVNTDKDHLRRWKELNDDLQMRNEMIQQAEQQTHVILEATQARLEKLRNKIIQAVFSVSGTKSLSTEISDNYILESLQRIISERSDFYNQLKQKGVKVPPLQQSDVSLPGKIKKMLSK", "length": 621 }, "evidence": [ { "id": "A0A3L7I9F9", "url": "https://omabrowser.org/oma/group/A0A3L7I9F9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2M243-1", "protein_name": "Coiled-coil domain-containing protein 27", "gene_name": "CCDC27", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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This record is derived from a genomic sequence (NW_003614045.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003504260", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504260" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I9X7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I9X7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Fabp7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I9X7", "locus": {} } ], "crossref": [ { "id": "100752143", "url": "https://www.ncbi.nlm.nih.gov/gene/100752143", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000463", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000463", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000566", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000566", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012674", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012674", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752143", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752143", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VAIRHYE", "url": "https://omabrowser.org/oma/group/VAIRHYE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7I9X7", "url": "https://www.orthodb.org/?gene=A0A3L7I9X7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11955", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11955", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00061", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00061", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003504260", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504260", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7I9X7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I9X7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7I9X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I9X7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVDAFCATWKLTDSQNFDEYMKALGVGFATRQVGNVTKPTVIISQEGGKVVIRTQCTFKNTEISFQLGEEFEETSIDDRNCKSVVRLDGDKLIHVQKWDGKETDCVREIKDGKMIVTLTFGDVVAVRCYEKA", "length": 132, "header": "tr|A0A3L7I9X7-1|A0A3L7I9X7_CRIGR Isoform 1 of Fatty acid-binding protein, brain OS=Cricetulus griseus OX=10029 GN=Fabp7 PE=3 SV=1 CANONICAL=A0A3L7I9X7-1" }, "isoforms": [ { "isoform_ac": "A0A3L7I9X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I9X7/entry#A0A3L7I9X7-1", "sequence": { "sequence": "MVDAFCATWKLTDSQNFDEYMKALGVGFATRQVGNVTKPTVIISQEGGKVVIRTQCTFKNTEISFQLGEEFEETSIDDRNCKSVVRLDGDKLIHVQKWDGKETDCVREIKDGKMIVTLTFGDVVAVRCYEKA", "length": 132, "header": "tr|A0A3L7I9X7-1|A0A3L7I9X7_CRIGR Isoform 1 of Fatty acid-binding protein, brain OS=Cricetulus griseus OX=10029 GN=Fabp7 PE=3 SV=1 CANONICAL=A0A3L7I9X7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I9X7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I9X7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7I9X7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7I9X7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752143", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752143", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O15540-1", "protein_name": "Fatty acid-binding protein, brain", "gene_name": "FABP7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVEAFCATWKLTNSQNFDEYMKALGVGFATRQVGNVTKPTVIISQEGDKVVIRTLSTFKNTEISFQLGEEFDETTADDRNCKSVVSLDGDKLVHIQKWDGKETNFVREIKDGKMVMTLTFGDVVAVRHYEKA", "length": 132 }, "evidence": [ { "id": "A0A3L7I9X7", "url": "https://omabrowser.org/oma/group/A0A3L7I9X7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P51880-1", "protein_name": "Fatty acid-binding protein, brain", "gene_name": "Fabp7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDAFCATWKLTDSQNFDEYMKALGVGFATRQVGNVTKPTVIISQEGGKVVIRTQCTFKNTEINFQLGEEFEETSIDDRNCKSVVRLDGDKLIHVQKWDGKETNCTREIKDGKMVVTLTFGDIVAVRCYEKA", "length": 132 }, "evidence": [ { "id": "A0A3L7I9X7", "url": "https://omabrowser.org/oma/group/A0A3L7I9X7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P55051-1", "protein_name": "Fatty acid-binding protein, brain", "gene_name": "Fabp7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDAFCATWKLTDSQNFDEYMKALGVGFATRQVGNVTKPTVIISQEGGKVVIRTQCTFKNTEISFQLGEEFEETSIDDRNCKSVIRLDGDKLIHVQKWDGKETNCVREIKDGKMVVTLTFGDVVAVRCYEKA", "length": 132 }, "evidence": [ { "id": "A0A3L7I9X7", "url": "https://omabrowser.org/oma/group/A0A3L7I9X7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q05423-1", "protein_name": "Fatty acid-binding protein, brain", "gene_name": "FABP7", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVEAFCATWKLADSHNFDEYMKALGVGFAMRQVGNVTKPTVIISSEGDKVVIRTQSTFKNTEISFKLGEEFDETTPDDRNCKSVVTLDGDKLVHVQKWDGKETNFVREIKDGRMVMTLTFGDVVAVRHYEKA", "length": 132 }, "evidence": [ { "id": "A0A3L7I9X7", "url": "https://omabrowser.org/oma/group/A0A3L7I9X7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q09139-1", "protein_name": "Fatty acid-binding protein, brain", "gene_name": "FABP7", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVEAFCATWKLTESQNFDEYMKALGVGFATRQVGNVTKPTVIISQEGDRVVIRTQSTFKNTEISFHLGEEFDETTADDRNCKSVVSLDGDKLVHVQKWDGKETNFVREIKDGKMIMTLTFGDVVAVRHYEKA", "length": 132 }, "evidence": [ { "id": "A0A3L7I9X7", "url": "https://omabrowser.org/oma/group/A0A3L7I9X7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": 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"enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 35, "end_pos": 37 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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"https://www.uniprot.org/uniprotkb/A0A3L7IA09" } ] }, { "name": "Ppp2r1a", "type": "synonym", "evidence": [ { "id": "XP_027254501", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254501" } ] } ], "protein_names": [ { "name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X2", "type": "synonym", "evidence": [ { "id": "A0A3L7IA09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IA09/entry#names_and_taxonomy" } ] }, { "name": "serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027254501", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254501" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027254501", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027254501" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IA09", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IA09" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ppp2r1a", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IA09", "locus": {} } ], "crossref": [ { "id": "100773447", "url": "https://www.ncbi.nlm.nih.gov/gene/100773447", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021133", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051023", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051023", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054573", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054573", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773447", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773447", "database": "KEGG 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"annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 270 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615112.1) and transcript sequences (IACG01060965.1 and JI883892.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003511490.2. 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"common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VHN3-1", "protein_name": "Cysteine-rich DPF motif domain-containing protein 1", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDPDDDLVLENEAEEIERLQLPEELKKPIDPEEEDERVARIEFNCSGCEMHEMVHYFGRKPPFALGVIYPEDNYVMRDPFQPPPPRWQSKPEYYIAMGTKCSICSKTVCKDPGCSFYYTASFCLPCGKEELKNWPPEAQARIRKQMSVSQGRQT", "length": 154 }, "evidence": [ { "id": "A0A3L7IAG9", "url": "https://omabrowser.org/oma/group/A0A3L7IAG9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3L7IAG9", "database": "UniProtKB", "url": 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7IAZ3-1", "uniprot_ac": "A0A3L7IAZ3", "uniprot_id": "A0A3L7IAZ3_CRIGR", "mass": { "chemical_mass": 37866.0, "monoisotopic_mass": 37866.0 }, "refseq": { "ac": "XP_003509455", "name": "transmembrane protein 68 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509455" }, "gene_names": [ { "name": "Tmem68", "type": "recommended", "evidence": [ { "id": "A0A3L7IAZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IAZ3" } ] }, { "name": "Tmem68", "type": "synonym", "evidence": [ { "id": "XP_003509455", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509455" } ] } ], "protein_names": [ { "name": "Transmembrane protein 68 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A3L7IAZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IAZ3/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 68 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003509455", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509455" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614707.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003509455", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509455" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IAZ3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tmem68", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IAZ3", "locus": {} } ], "crossref": [ { "id": "cd07987", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07987", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100754539", "url": "https://www.ncbi.nlm.nih.gov/gene/100754539", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754539", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754539", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SYWNGAR", "url": "https://omabrowser.org/oma/group/SYWNGAR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7IAZ3", "url": "https://www.orthodb.org/?gene=A0A3L7IAZ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FAD9", "url": "https://www.orthodb.org/?gene=A0A9J7FAD9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22753", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22753", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22753:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22753:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01553", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01553", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003509455", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509455", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7IAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IAZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7IAZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IAZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FAD9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FAD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FAD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FAD9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLDNNQTCTVGQDCVPYMTCVVHMLEEWLGVEQLEDYLNFANYLLWVFTPLLLLILPYFTIFLLYITIIFLHIYKRKNVLKEAYSHNLWDGARKTVATLWDGHAAVWHGYEVHGMEKIPEGPALIIFYHGAIPIDFYYFMAKIFIHKGRACRVVADHFVFKIPGFSLLLDVFCALHGPREKCVEILRSGHLLAISPGGVREALLSDETYNIIWGNRKGFAQVAIDAKVPIIPMFTQNIREGFRSLGGTRLFKWLYEKFRYPFAPLYGGFPVKLRTYLGDPIPYDPKITAEELAEKTKNALQALIDKHQRIPGNIRSALLDRFHRGQQAN", "length": 329, "header": "tr|A0A3L7IAZ3-1|A0A3L7IAZ3_CRIGR Isoform 1 of Transmembrane protein 68 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tmem68 PE=4 SV=1 CANONICAL=A0A3L7IAZ3-1" }, "isoforms": [ { "isoform_ac": "A0A3L7IAZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IAZ3/entry#A0A3L7IAZ3-1", "sequence": { "sequence": "MLDNNQTCTVGQDCVPYMTCVVHMLEEWLGVEQLEDYLNFANYLLWVFTPLLLLILPYFTIFLLYITIIFLHIYKRKNVLKEAYSHNLWDGARKTVATLWDGHAAVWHGYEVHGMEKIPEGPALIIFYHGAIPIDFYYFMAKIFIHKGRACRVVADHFVFKIPGFSLLLDVFCALHGPREKCVEILRSGHLLAISPGGVREALLSDETYNIIWGNRKGFAQVAIDAKVPIIPMFTQNIREGFRSLGGTRLFKWLYEKFRYPFAPLYGGFPVKLRTYLGDPIPYDPKITAEELAEKTKNALQALIDKHQRIPGNIRSALLDRFHRGQQAN", "length": 329, "header": "tr|A0A3L7IAZ3-1|A0A3L7IAZ3_CRIGR Isoform 1 of Transmembrane protein 68 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tmem68 PE=4 SV=1 CANONICAL=A0A3L7IAZ3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FAD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IAZ3/entry#A0A9J7FAD9-1", "sequence": { "sequence": "MLDNNQTCTVGQDCVPYMTCVVHMLEEWLGVEQLEDYLNFANYLLWVFTPLLLLILPYFTIFLLYITIIFLHIYKRKNVLKEAYSHNLWDGARKTVATLWDGHAAVWHGYEVHGMEKIPEGPALIIFYHGAIPIDFYYFMAKIFIHKGRACRVVADHFVFKIPGFSLLLDVFCALHGPREKCVEILRSGHLLAISPGGVREALLSDETYNIIWGNRKGFAQVAIDAKVPIIPMFTQNIREGFRSLGGTRLFKWLYEKFRYPFAPLYGGFPVKLRTYLGDPIPYDPKITAEELAEKANT", "length": 298, "header": "tr|A0A9J7FAD9-1|A0A9J7FAD9_CRIGR Computationally mapped isoform of Transmembrane protein 68 isoform X2 OS=Cricetulus griseus OX=10029 GN=Tmem68 PE=4 SV=1 CANONICAL=A0A3L7IAZ3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IAZ3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IAZ3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IAZ3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754539", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754539", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PUT3-1", "protein_name": "Transmembrane protein 68", "gene_name": "TMEM68", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MIGSNESSTEGPIPTSYLSFLAYLLGEWTGVEHTEDYLSYGAYLSWVLFPLAIVFILPVAIFFFCFNTSLLLLHIYKRRKNGFNEGHSGDVWYGAKEMLANLWDGHGRVWHGYELHGDENIPEGPALIVFYHGASPVDYLYFMARLLIRRKRYCHVVADHFVFRLPGLKMFIEVLGVMHGPKEVCVSALKKGYLLAISPGGVREALFSDETYAIMWGNRKGFAQVAIDAKVPIIPMFTQNVREGIRTLGGIKIFRKLYERIRLPIVPMYGWFPVKFRTFIGEPIPYDPNITAEELTAKTKAALQALITKHQKIPGNILRALMERFQTRQKED", "length": 332 }, "evidence": [ { "id": "A0A3L7IAZ3", "url": "https://omabrowser.org/oma/group/A0A3L7IAZ3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8D1WF85-1", "protein_name": "Transmembrane protein 68", "gene_name": "TMEM68", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MIGKNQTCGTGQDSMPYMTCLVHILEGWFGVEQLEDYLNFANYLLWVFTPLILLILPYFTIFLLYLTIIFLHIYKRKNVLREAYSHNLWDGARKTVATLWDGHAAVWHGYEVHGMEKIPEEGPALIIFYHGAIPIDFYYFMAKIFIHKGRTCRVVADHFVFKIPGFSLLLDVFCALHGPREKCVEILRSGHLLAISPGGVREALLSDETYNIVWGNRKGFAQVAIDAKVPIIPMFTQNIREGFRSLGGTRLFRWLYEKFRYPFAPMYGGFPVKLRTYLGDPIPYDPKITAEELAEKTKDAVQALIDKHQRIPGNIMSALLERFHKKQKIN", "length": 330 }, "evidence": [ { "id": "A0A3L7IAZ3", "url": "https://omabrowser.org/oma/group/A0A3L7IAZ3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZF19-1", "protein_name": "Transmembrane protein 68", "gene_name": "Tmem68", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MINNNQTCAAGQDSVPYVTCMLHVLEEWLGVEQLEDYLNFANHLLWVFTPLILLILPYFTIFLLYLTIIFLHIYKRKNVLKEAYSHNLWDGARKTVATLWDGHAAVWHGYEVHGMEKIPEGPALIIFYHGAIPIDFYYFMAKIFIHKGRTCRVVADHFVFKIPGFSLLLDVFCALHGPREKCVEILRSGHLLAISPGGVREALLSDETYNIIWGNRKGFAQVAIDAKVPIIPMFTQNIREGFRSLGGTRLFKWLYEKFRYPFAPMYGGFPVKLRTFLGDPIPYDPEVTAEELAEKTKNAVQALIDKHQRIPGNIRSALLDRFHKEQKAN", "length": 329 }, "evidence": [ { "id": "A0A3L7IAZ3", "url": "https://omabrowser.org/oma/group/A0A3L7IAZ3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0VCR6-1", "protein_name": "DGAT1/2-independent enzyme synthesizing storage lipids", "gene_name": "TMEM68", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTNKNQSFGVGQDSMSSMTCLIHVLEAWFGVEHLEDYWNFANYLLWVFTPLLLLILPYFTIFLLYLTIIFLHIYKRKNVLKEAYSHNLWDGARKTVATLWDGHAAVWHGYEVHGMEKIPEEGPALIIFYHGAIPIDFYYFMAKIFIHKGRTCRVVADHFVFKIPGFSLLLDVFCAIHGPREKCVEILQSGHLLAISPGGVREALMSDETYNIVWGNRKGFAQVAIDAKVPIIPMFTQNIREGFRSLGGTRLFRWLYEKFRYPFAPMYGGFPVKLRTYLGDPIPYDPKITAEELAEKTKDAVQALIDKHQRIPGNIMSALLERFRNKQKINQKTL", "length": 334 }, "evidence": [ { "id": "A0A3L7IAZ3", "url": "https://omabrowser.org/oma/group/A0A3L7IAZ3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q96MH6-1", "protein_name": "DGAT1/2-independent enzyme synthesizing storage lipids", "gene_name": "TMEM68", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIDKNQTCGVGQDSVPYMICLIHILEEWFGVEQLEDYLNFANYLLWVFTPLILLILPYFTIFLLYLTIIFLHIYKRKNVLKEAYSHNLWDGARKTVATLWDGHAAVWHGYEVHGMEKIPEDGPALIIFYHGAIPIDFYYFMAKIFIHKGRTCRVVADHFVFKIPGFSLLLDVFCALHGPREKCVEILRSGHLLAISPGGVREALISDETYNIVWGHRRGFAQVAIDAKVPIIPMFTQNIREGFRSLGGTRLFRWLYEKFRYPFAPMYGGFPVKLRTYLGDPIPYDPQITAEELAEKTKNAVQALIDKHQRIPGNIMSALLERFH", "length": 324 }, "evidence": [ { "id": "A0A3L7IAZ3", "url": "https://omabrowser.org/oma/group/A0A3L7IAZ3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D850-1", "protein_name": "DGAT1/2-independent enzyme synthesizing storage lipids", "gene_name": "Tmem68", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIDNNQTCAAGQDSVPYVTCMIYVLEEWLGVEQLEDYLNFANHLLWVFTPLILLILPYFTIFLLYLTIIFLHIYKRKNVLKEAYSHNLWDGARKTVATLWDGHAAVWHGYEVHGMEKIPEGAALIIFYHGAIPIDFYYFMAKIFIQKGRTCRVVADHFVFKIPGFSLLLDVFCALHGPREKCVEILRSGHLLAISPGGVREALLSDETYNIIWGNRKGFAQVAIDAKVPIIPMFTQNIREGFRSLGGTRLFKWLYEKFRYPFAPMYGGFPVKLRTFLGDPIPYDPKVTAEELAEKTKNAVQALIDKHQRIPGNIRSALLDRFHKEQKAH", "length": 329 }, "evidence": [ { "id": "A0A3L7IAZ3", "url": "https://omabrowser.org/oma/group/A0A3L7IAZ3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VZ05-1", "protein_name": "Phospholipid/glycerol acyltransferase domain-containing protein", "gene_name": "CG15197", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": 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This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. 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"glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A8Y5T1-1", "protein_name": "Protein CFAP276", "gene_name": "cfap276", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPQERDPFPFPRYENDFTLTGRKEIQKLSDDKPTHLAQNDEPWRRLHNTTTEASSRRTVFHYDTTTPKDSLDIHLKAAYDHHLGLFQNKSQTVMQMETVGADNGTKKNKELEDSVCDAENKGIKVWVDTQKASLYSIKGSIESHHTASTNRGYSRKHDGGFYST", "length": 164 }, "evidence": [ { "id": "A0A3L7ICK6", "url": "https://omabrowser.org/oma/group/A0A3L7ICK6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZNI7-1", "protein_name": "Cilia and flagella associated protein 276", "gene_name": "Cfap276", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPHSQESYPNPAVGDKDTHLGNLLASKKSTFKNPTHLVQQQDTWNRLSSASTATSIRRDAYFYDPKIPKDDLDFRLAALYDHHTGAFKNKTEILLHQETIEDMQGTKLQFPGECFHSPSAPITSRTTIRHWINPKKESIHSIQGSIVSPHTAATNGGYSRKNDGGFFST", "length": 169 }, "evidence": [ { "id": "A0A3L7ICK6", "url": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7IDT5-1", "uniprot_ac": "A0A3L7IDT5", "uniprot_id": "A0A3L7IDT5_CRIGR", "mass": { "chemical_mass": 28599.0, "monoisotopic_mass": 28599.0 }, "refseq": { "ac": "XP_003501211", "name": "protein MGARP", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501211" }, "gene_names": [ { "name": "Mgarp", "type": 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:: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613834.1) annotated using gene prediction method: Gnomon. 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IDT5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IDT5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IDT5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IDT5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763385", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763385", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y0I9-1", "protein_name": "Mitochondria localized glutamic acid rich protein", "gene_name": "MGARP", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MYLCRAASQALAARLSRAPSAASRLTQRAPLRQMSSGSVPGSSGENMIYYLITGVAAFGALFYTYKVVGSSRSNYIEHVNVLHERGQKHKADSYKGDEEETAEVTGADVATEEADASTAAGPAAQEESSGVTPETGGESDLPAADTSTAVEGAQQEAAANSEAPAVQETVSEVLDVAASSAHEENLDSVKEGVASAAQEMSDTAMRNRDADAEESGRASEGAGVQLISEEEKAPEEVAKEP", "length": 241 }, "evidence": [ { "id": "A0A3L7IDT5", "url": "https://omabrowser.org/oma/group/A0A3L7IDT5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A6QLZ1-1", "protein_name": "Protein MGARP", "gene_name": "MGARP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MYLRRAVSKTLALPLRAPPGPAPLRKDASLRWISSNKFPGSSGSNMIYYLVVGVTVSAGGYYTYKRVTSGKAKRSDHVTDLKEKTKAELQPPQGEKENLVGAEEASLEAPEVSSTEASPVVTEDIPDAPAVVGKEAPPCPDDAEAAPSETVVVGAEPKPEMTDAATVETTEVSTETTSEVTSTGPEEAAAVDSAEGTTENESPGECAELEENSPVESESSAGEDLQEEACAGSEAASAQG", "length": 240 }, "evidence": [ { "id": "A0A3L7IDT5", "url": "https://omabrowser.org/oma/group/A0A3L7IDT5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D4A4W7-1", "protein_name": "Mitochondria-localized glutamic acid-rich protein", "gene_name": "Mgarp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQPLSGCPGAQSNTTRAGAVSKTLALPRRAPPGPAPLGKDASLRRVSSSKFPGPSGSNMIYYLVVGVTVSAGGYYTYKAFTSKQVRHTEHVTDPKEQTKAELQPLPGETEHVAEAGKACSETGEISVKESDSVDAEEVPEAAAVLPEESQASASEVPAEAALVETSVLSSEPELKITDDHDASPVETTEGVPESPPEVEGAAPDQADVCSEGVDDNSKEGAETSKEGAETSKEEAETSKEAEGTTTADAEEEESAENAELEESPPLTSEPSAQPESQEETEVTAEAASPQG", "length": 291 }, "evidence": [ { "id": "A0A3L7IDT5", "url": "https://omabrowser.org/oma/group/A0A3L7IDT5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RRC9-1", "protein_name": "Mitochondria localized glutamic acid rich protein", "gene_name": "MGARP", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSNKFPGTSGSNMMYYLLVGVTVSAGGYYTYKTVKRQAKHSEHTANMKEKTKAELHPPQGEKENLVSAEEASSDAPVVSLAEAPVVDAEDTPQATVTAIEEASPCPDNMEAAPAETLGAETGPEVTDAAATVETAEVGPEVTLEVTGTPLDEAVAIDSGKGTTENETHGENAELEENSPVESESSAGGDLQEEAGGASEAASPLG", "length": 206 }, "evidence": [ { "id": "A0A3L7IDT5", "url": "https://omabrowser.org/oma/group/A0A3L7IDT5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8TDB4-1", "protein_name": "Protein MGARP", "gene_name": "MGARP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYLRRAVSKTLALPLRAPPNPAPLGKDASLRRMSSNRFPGSSGSNMIYYLVVGVTVSAGGYYAYKTVTSDQAKHTEHKTNLKEKTKAEIHPFQGEKENVAETEKASSEAPEELIVEAEVVDAEESPSATVVVIKEASACPGHVEAAPETTAVSAETGPEVTDAAARETTEVNPETTPEVTNAALDEAVTIDNDKDTTKNETSDEYAELEEENSPAESESSAGDDLQEEASVGSEAASAQG", "length": 240 }, "evidence": [ { "id": "A0A3L7IDT5", "url": "https://omabrowser.org/oma/group/A0A3L7IDT5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VI64-1", "protein_name": "Protein MGARP", "gene_name": "Mgarp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYLRRAVSKTLALPRRAPPGPAPLGKDASLRRMSSRKFPGTSGSNMIYYLVVGVTVSAGGYYTYKALTSKQVRRTEHVAEPKEQTKAELQPLPGEKEEHVAEAEQVCSEPGDTAVTEAESVDAEEVPEAAVVLPEESQASAPSEVPAEAAVVEASLSSSEPELKITEASLVETTESVPESTQEVESAAPDQDDVCNEGADTSQEGADTSQEGADTSQEGADTTKEEADNSKEAEGTTTEDPRSISEESAELEESPPLGSEPPAQPESQEEETQVTEETASPQG", "length": 283 }, "evidence": [ { "id": "A0A3L7IDT5", "url": "https://omabrowser.org/oma/group/A0A3L7IDT5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IDT5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IDT5" } ], "pmid": "" }, { "name": "axon cytoplasm", "id": "GO:1904115", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904115", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IDT5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IDT5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "anterograde axonal transport", "id": "GO:0008089", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008089", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IDT5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IDT5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3L7IDT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IDT5" }, { "id": "PF14962", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14962" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein MGARP N-terminal", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 191, "start_aa": "Met", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 22 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", 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"tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7IEA3-1", "uniprot_ac": "A0A3L7IEA3", "uniprot_id": "A0A3L7IEA3_CRIGR", "mass": { "chemical_mass": 10416.0, "monoisotopic_mass": 10416.0 }, "refseq": { "ac": "XP_016829506", "name": "39S ribosomal protein L34, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016829506" }, "gene_names": [ { "name": "Mrpl34", "type": "recommended", "evidence": [ { "id": "A0A3L7IEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEA3" } ] }, { "name": "Mrpl34", "type": "synonym", "evidence": [ { "id": "XP_016829506", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016829506" } ] } ], "protein_names": [ { "name": "Large ribosomal subunit protein bL34m", "type": "recommended", "evidence": [ { "id": "A0A3L7IEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEA3/entry#names_and_taxonomy" } ] }, { "name": "39S ribosomal protein L34, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_016829506", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016829506" }, { "id": "A0A3L7IEA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEA3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613716.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016829506", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016829506" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IEA3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEA3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mrpl34", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEA3", "locus": {} } ], "crossref": [ { "id": "100755355", "url": "https://www.ncbi.nlm.nih.gov/gene/100755355", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755355", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755355", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LQPRVWM", "url": "https://omabrowser.org/oma/group/LQPRVWM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7IEA3", "url": "https://www.orthodb.org/?gene=A0A3L7IEA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14503", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14503", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14503:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14503:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00468", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00468", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016829506", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016829506", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7IEA3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7IEA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEA3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASLARNFGYPACRSAAQLGGRWLQPRVWMGLADAWGLPSLQPARGRTRGNEYQPSNIKRKHKHGWIRRLSTPAGVQVILRRMLKGRKSLSH", "length": 92, "header": "tr|A0A3L7IEA3-1|A0A3L7IEA3_CRIGR Isoform 1 of Large ribosomal subunit protein bL34m OS=Cricetulus griseus OX=10029 GN=Mrpl34 PE=3 SV=1 CANONICAL=A0A3L7IEA3-1" }, "isoforms": [ { "isoform_ac": "A0A3L7IEA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEA3/entry#A0A3L7IEA3-1", "sequence": { "sequence": "MASLARNFGYPACRSAAQLGGRWLQPRVWMGLADAWGLPSLQPARGRTRGNEYQPSNIKRKHKHGWIRRLSTPAGVQVILRRMLKGRKSLSH", "length": 92, "header": "tr|A0A3L7IEA3-1|A0A3L7IEA3_CRIGR Isoform 1 of Large ribosomal subunit protein bL34m OS=Cricetulus griseus OX=10029 GN=Mrpl34 PE=3 SV=1 CANONICAL=A0A3L7IEA3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IEA3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEA3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IEA3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEA3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755355", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755355", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1UFR4-1", "protein_name": "Large ribosomal subunit protein bL34m", "gene_name": "MRPL34", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAFLARSVGRLLDPVSRSAALVGGRWLQPQAWLGFPDTWGLPAMQQTRGKARGNEYQPSNIKRKHKHGWVRRLRTPTGVQVILRRMHKGRKSLSH", "length": 95 }, "evidence": [ { "id": "A0A3L7IEA3", "url": "https://omabrowser.org/oma/group/A0A3L7IEA3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A8NN94-1", "protein_name": "Large ribosomal subunit protein bL34m", "gene_name": "MRPL34", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAFSVGSVGCLLGPVSRSAGLLGGRWLQGSRAWLGLPDTRRLPVIQQTRGRTRGNEYQPSNIKRKNKHGWIRRLSTPNGVQVILRRMHKGRKSLSH", "length": 96 }, "evidence": [ { "id": "A0A3L7IEA3", "url": "https://omabrowser.org/oma/group/A0A3L7IEA3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q99N91-1", "protein_name": "Large ribosomal subunit protein bL34m", "gene_name": "Mrpl34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFLARCFGCQACRSVALLSGRYLQSRVWMGLPDSWPLLSLQQARGRARGNEYQPSNIKRKHKHGWVRRLSTPAGVQVILRRMLKGRKSLSH", "length": 92 }, "evidence": [ { "id": "A0A3L7IEA3", "url": "https://omabrowser.org/oma/group/A0A3L7IEA3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BQ48-1", "protein_name": "Large ribosomal subunit protein bL34m", "gene_name": "MRPL34", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVLAGSLLGPTSRSAALLGGRWLQPRAWLGFPDAWGLPTPQQARGKARGNEYQPSNIKRKNKHGWVRRLSTPAGVQVILRRMLKGRKSLSH", "length": 92 }, "evidence": [ { "id": "A0A3L7IEA3", "url": "https://omabrowser.org/oma/group/A0A3L7IEA3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial large ribosomal subunit", "id": "GO:0005762", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005762", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IEA3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEA3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IEA3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEA3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IEA3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEA3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7IER4-1", "uniprot_ac": "A0A3L7IER4", "uniprot_id": "A0A3L7IER4_CRIGR", "mass": { "chemical_mass": 11401.0, "monoisotopic_mass": 11401.0 }, "refseq": { "ac": "XP_003504201", "name": "coiled-coil domain-containing protein 167", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504201" }, "gene_names": [ { "name": "Ccdc167", "type": "recommended", "evidence": [ { "id": "A0A3L7IER4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER4" } ] }, { "name": "Ccdc167", "type": "synonym", "evidence": [ { "id": "XP_003504201", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504201" } ] } ], "protein_names": [ { "name": "Coiled-coil domain-containing protein 167", "type": "recommended", "evidence": [ { "id": "A0A3L7IER4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER4/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 167", "type": "synonym", "evidence": [ { "id": "XP_003504201", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504201" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614036.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003504201", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504201" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IER4", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ccdc167", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER4", "locus": {} } ], "crossref": [ { "id": "100755674", "url": "https://www.ncbi.nlm.nih.gov/gene/100755674", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028194", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028194", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755674", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755674", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MAIMNER", "url": "https://omabrowser.org/oma/group/MAIMNER/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7IER4", "url": "https://www.orthodb.org/?gene=A0A3L7IER4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31759", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31759", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31759:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31759:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15188", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15188", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003504201", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504201", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7IER4", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7IER4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTKKKRENLGVAQEIDGLEEKLSQCRKDLEAVTSQLYRTELSPEDRRSLEKEKTTLMSKASKYEKELKLLRQENRKNMLLSVAIFILLALLYAHWTM", "length": 97, "header": "tr|A0A3L7IER4-1|A0A3L7IER4_CRIGR Isoform 1 of Coiled-coil domain-containing protein 167 OS=Cricetulus griseus OX=10029 GN=Ccdc167 PE=4 SV=1 CANONICAL=A0A3L7IER4-1" }, "isoforms": [ { "isoform_ac": "A0A3L7IER4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER4/entry#A0A3L7IER4-1", "sequence": { "sequence": "MTKKKRENLGVAQEIDGLEEKLSQCRKDLEAVTSQLYRTELSPEDRRSLEKEKTTLMSKASKYEKELKLLRQENRKNMLLSVAIFILLALLYAHWTM", "length": 97, "header": "tr|A0A3L7IER4-1|A0A3L7IER4_CRIGR Isoform 1 of Coiled-coil domain-containing protein 167 OS=Cricetulus griseus OX=10029 GN=Ccdc167 PE=4 SV=1 CANONICAL=A0A3L7IER4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IER4", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IER4", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IER4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755674", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755674", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AUD4-1", "protein_name": "Coiled-coil domain-containing protein 167", "gene_name": "CCDC167", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTKKKRENLGVALEIDGLEEKLSQCRRELEAVNSRLYGAELSPEARRSLEKEKSSLMSKASNYEKELKLLRQENRKNMLLSVVIFILLTFLYAYWTT", "length": 97 }, "evidence": [ { "id": "A0A3L7IER4", "url": "https://omabrowser.org/oma/group/A0A3L7IER4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": 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"OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1A4P9-1", "protein_name": "Coiled-coil domain-containing protein 167", "gene_name": "CCDC167", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTKKKRENLGVALEIDGLEKKLSQCRRDLEVVNSRLCGVELSSEARRSLEKEKSSLMNKASNYEKELKLLRQENRKNMLLSVAIFLLLTVIYAYWAL", "length": 97 }, "evidence": [ { "id": "A0A3L7IER4", "url": "https://omabrowser.org/oma/group/A0A3L7IER4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5RHZ2-1", "protein_name": "Coiled-coil domain-containing protein 167", "gene_name": "ccdc167", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTRTRTVKKEKISVASEIDRVEERKLQCKNSLERAEFRKRKQQLSDDDRLALEDEMTILNERVEKYEKDLQVLRGENRRNMMLSVALLAISALFYYTFIY", "length": 100 }, "evidence": [ { "id": "A0A3L7IER4", "url": "https://omabrowser.org/oma/group/A0A3L7IER4/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9D162-1", "protein_name": "Coiled-coil domain-containing protein 167", "gene_name": "Ccdc167", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKKKRENLGVAQEIDGLEEKLSRCRKDLEAVTSQLYRAELSPEDRRSLEKEKHTLMNKASKYEKELKLLRHENRKNTLLSVAIFTVFALLYAYWTM", "length": 97 }, "evidence": [ { "id": "A0A3L7IER4", "url": "https://omabrowser.org/oma/group/A0A3L7IER4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9P0B6-1", "protein_name": "Coiled-coil domain-containing protein 167", "gene_name": "CCDC167", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTKKKRENLGVALEIDGLEEKLSQCRRDLEAVNSRLHSRELSPEARRSLEKEKNSLMNKASNYEKELKFLRQENRKNMLLSVAIFILLTLVYAYWTM", "length": 97 }, "evidence": [ { "id": "A0A3L7IER4", "url": "https://omabrowser.org/oma/group/A0A3L7IER4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ 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"uniprot_canonical_ac": "A0A3L7IEU5-1", "uniprot_ac": "A0A3L7IEU5", "uniprot_id": "A0A3L7IEU5_CRIGR", "mass": { "chemical_mass": 34737.0, "monoisotopic_mass": 34737.0 }, "refseq": { "ac": "XP_027249863", "name": "methylsterol monooxygenase 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249863" }, "gene_names": [ { "name": "Msmo1", "type": "recommended", "evidence": [ { "id": "A0A3L7IEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEU5" } ] }, { "name": "Msmo1", "type": "synonym", "evidence": [ { "id": "XP_027249863", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249863" } ] } ], "protein_names": [ { "name": "Methylsterol monooxygenase 1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A3L7IEU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEU5/entry#names_and_taxonomy" } ] }, { "name": "methylsterol monooxygenase 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027249863", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249863" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027249863", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249863" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IEU5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEU5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Msmo1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEU5", "locus": {} } ], "crossref": [ { "id": "100754784", "url": "https://www.ncbi.nlm.nih.gov/gene/100754784", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006694", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006694", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050307", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050307", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754784", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754784", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3L7IEU5", "url": "https://www.orthodb.org/?gene=A0A3L7IEU5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11863", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11863", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04116", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04116", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027249863", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249863", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7IEU5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7IEU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEU5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8H3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8H3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8H3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATNKSADIFSSASLAVEYVDSLLPENPLQEPFKNAWGYMLDNYTKFQIATWGSLIVHEAIYFLFSLPGFLFQFIPFMRKYKIQKDKPETLEGQWKCLKGLLFNHFCIQLPMICGTYYFTEYFNIPYDWERMPRWFMILARCLGCAVIEDTWHYFLHRLLHHKRIYKYIHKIHHEFQAPFGIEAEYAHPLETIILGTGFFIGIVLLCDHVILLWAWVTVRLLETIDVHSGYYIPINPLNFIPFYTGSRHHDFHHMNFIGNYASTFTWWDRIFGTDAQYHAYNEKLKKLGKKD", "length": 292, "header": "tr|A0A3L7IEU5-1|A0A3L7IEU5_CRIGR Isoform 1 of Methylsterol monooxygenase 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Msmo1 PE=4 SV=1 CANONICAL=A0A3L7IEU5-1" }, "isoforms": [ { "isoform_ac": "A0A3L7IEU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEU5/entry#A0A3L7IEU5-1", "sequence": { "sequence": "MATNKSADIFSSASLAVEYVDSLLPENPLQEPFKNAWGYMLDNYTKFQIATWGSLIVHEAIYFLFSLPGFLFQFIPFMRKYKIQKDKPETLEGQWKCLKGLLFNHFCIQLPMICGTYYFTEYFNIPYDWERMPRWFMILARCLGCAVIEDTWHYFLHRLLHHKRIYKYIHKIHHEFQAPFGIEAEYAHPLETIILGTGFFIGIVLLCDHVILLWAWVTVRLLETIDVHSGYYIPINPLNFIPFYTGSRHHDFHHMNFIGNYASTFTWWDRIFGTDAQYHAYNEKLKKLGKKD", "length": 292, "header": "tr|A0A3L7IEU5-1|A0A3L7IEU5_CRIGR Isoform 1 of Methylsterol monooxygenase 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Msmo1 PE=4 SV=1 CANONICAL=A0A3L7IEU5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H8H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEU5/entry#A0A9J7H8H3-1", "sequence": { "sequence": "MQSVAIVDKPETLEGQWKCLKGLLFNHFCIQLPMICGTYYFTEYFNIPYDWERMPRWFMILARCLGCAVIEDTWHYFLHRLLHHKRIYKYIHKIHHEFQAPFGIEAEYAHPLETIILGTGFFIGIVLLCDHVILLWAWVTVRLLETIDVHSGYYIPINPLNFIPFYTGSRHHDFHHMNFIGNYASTFTWWDRIFGTDAQYHAYNEKLKKLGKKD", "length": 214, "header": "tr|A0A9J7H8H3-1|A0A9J7H8H3_CRIGR Computationally mapped isoform of Methylsterol monooxygenase 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Msmo1 PE=4 SV=1 CANONICAL=A0A3L7IEU5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IEU5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEU5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"A0A3L7IEU5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEU5" } ], "pmid": "" }, { "name": "monooxygenase activity", "id": "GO:0004497", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004497", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IEU5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEU5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IEU5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEU5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cholesterol biosynthetic process via desmosterol", "id": "GO:0033489", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033489", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IEU5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IEU5" } ], "pmid": "" }, { "name": "zymosterol biosynthetic 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This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_003613976.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003503551", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503551" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IH46", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IH46" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Actrt3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IH46", "locus": {} } ], "crossref": [ { "id": "cd13397", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13397", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100768343", "url": "https://www.ncbi.nlm.nih.gov/gene/100768343", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100768343", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768343", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WEDMEIM", "url": "https://omabrowser.org/oma/group/WEDMEIM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7IH46", "url": "https://www.orthodb.org/?gene=A0A3L7IH46", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11937", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11937", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00022", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00022", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003503551", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503551", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7IH46", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IH46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7IH46-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IH46-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSGYQPPVVIDNGSGMIKAGLAGTREPQFVYPNILGRTKGHKTAVNCGQELCVGDQAQERRSFLSISYPMDRGLISSWGDMEIMWKHIYDYNLNLKASDGPVLVTEPALNPMVDRQHISEVFFETLGVPAFYLSVQAVLALFAAGFTTGLVLNSGAGISQCVPVFEGYCLPHGVKQLNVAGLDLTHYLMMLLKEDGVMLLRTEDRKIVSDIKENACYVAMNYEDEMVKEPSLQKIYTLPDGKTIKLSNQVFRCPEALFSPWLVNVDAPGIDKMCLSSIMKCDTDLRNSFFSNIILAGGSTSFPGLDKRLIKDVAKMAPANTPVQVTAPPERKISVWMGGSILASLSAFQDMWITAAEFEEVGPNIVHQRCF", "length": 371, "header": "tr|A0A3L7IH46-1|A0A3L7IH46_CRIGR Isoform 1 of Actin-related protein T3 OS=Cricetulus griseus OX=10029 GN=Actrt3 PE=3 SV=1 CANONICAL=A0A3L7IH46-1" }, "isoforms": [ { "isoform_ac": "A0A3L7IH46-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IH46/entry#A0A3L7IH46-1", "sequence": { "sequence": "MSGYQPPVVIDNGSGMIKAGLAGTREPQFVYPNILGRTKGHKTAVNCGQELCVGDQAQERRSFLSISYPMDRGLISSWGDMEIMWKHIYDYNLNLKASDGPVLVTEPALNPMVDRQHISEVFFETLGVPAFYLSVQAVLALFAAGFTTGLVLNSGAGISQCVPVFEGYCLPHGVKQLNVAGLDLTHYLMMLLKEDGVMLLRTEDRKIVSDIKENACYVAMNYEDEMVKEPSLQKIYTLPDGKTIKLSNQVFRCPEALFSPWLVNVDAPGIDKMCLSSIMKCDTDLRNSFFSNIILAGGSTSFPGLDKRLIKDVAKMAPANTPVQVTAPPERKISVWMGGSILASLSAFQDMWITAAEFEEVGPNIVHQRCF", "length": 371, "header": "tr|A0A3L7IH46-1|A0A3L7IH46_CRIGR Isoform 1 of Actin-related protein T3 OS=Cricetulus griseus OX=10029 GN=Actrt3 PE=3 SV=1 CANONICAL=A0A3L7IH46-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IH46", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IH46" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IH46", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IH46" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768343", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768343", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4ABA6-1", "protein_name": "Actin-related protein T3", "gene_name": "Actrt3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"MRLGKEIDKVLFQEFEKHEPCPALYDTFLVQISAPFVDFKGASDNFPQEPGQASRSQGSPSSRETGGGGGGMSYYQLPVVIDNGSGVIKAGLAGSREPQFVYSNIVGRTKGLTCGVEVCVGDQAEQRRSSLSISYPVERGLITSWGDMEIMWKHIYDDNLRLKPCDGPVLITESALNPLANRQRVTEVFFEYLEVPAFFMSVQGVLALFAAGFTTGFVLNSGAGVTQCVPIFEGYCLPHGVQQLDLAGLDLTNYLMMLLKENGIMLLRTSERKIITDIKETYCYVAMNFEEEKAKKADCIEKIYQLPDGKRFKLHNQLFYCPEALFSPSLMHLETPGIDKMCFSSIMKCDADLRNAFFSNIILAGGSTSFPGLEKRLVKDIAKMVPANTPVQVIAPPERKISVWMGGSILASLSAFQDMWITAAEYKEVGSNIVHQRCF", "length": 439 }, "evidence": [ { "id": "A0A3L7IH46", "url": "https://omabrowser.org/oma/group/A0A3L7IH46/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BXF8-1", "protein_name": "Actin-related protein T3", "gene_name": "Actrt3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGYQPPVVIDNGSGMIKAGLAGTREPQFVYPNILGRSKGHTADSRQELCVGDQAQERRSFLSISYPVERGLISSWGDMEIMWKHIYDYNLNLNASDGPVLVTEPALNPLADRQHISEVFFENLGVPAFYMSAQAVLALFAAGFTTGLVLNSGAGITQCVPIFEGYCLSHGVKQLNVAGSDLTSYLMMLLKGDGIMLLRTGDRKVVTDIKENACYVAMNYEDEMTKDSNLEKIYTLPDGKTVKLHKQLFHCPEALFSPYLVNVDAPGIDKMCFGSIMKCDTDLRNSFFSNIILSGGSTSFPGLDKRLIKDVAKLAPANTAVQVIAPPERKISVWMGGSILASLSAFQDMWITAAEFEEVGPNIVHQRCF", "length": 369 }, "evidence": [ { "id": "A0A3L7IH46", "url": "https://omabrowser.org/oma/group/A0A3L7IH46/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BYD9-1", "protein_name": "Actin-related protein T3", "gene_name": "ACTRT3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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This record is derived from a genomic sequence (NW_003615148.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007650284", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007650284" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IHA0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHA0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rpl22l1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHA0", "locus": {} } ], "crossref": [ { "id": "100750612", "url": "https://www.ncbi.nlm.nih.gov/gene/100750612", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038526", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038526", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100750612", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750612", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WIRFIST", "url": "https://omabrowser.org/oma/group/WIRFIST/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7IHA0", "url": "https://www.orthodb.org/?gene=A0A3L7IHA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7J731", "url": "https://www.orthodb.org/?gene=A0A9J7J731", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10064", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10064", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10064:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10064:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007650284", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007650284", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7IHA0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7IHA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHA0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J731", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J731", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J731-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J731-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPQKDKKPKKSTWRFHLDLTHPVEDGIFDSGNFEQFLREKVKVNGKTGNLGNVVHIERLKNKITVVSEKQFSKRYLKYLTKKYLKKNNLRDWLRVVASDKETYELRYFQISQDEDGSESED", "length": 122, "header": "tr|A0A3L7IHA0-1|A0A3L7IHA0_CRIGR Isoform 1 of 60S ribosomal protein L22-like 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Rpl22l1 PE=3 SV=1 CANONICAL=A0A3L7IHA0-1" }, "isoforms": [ { "isoform_ac": "A0A3L7IHA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHA0/entry#A0A3L7IHA0-1", "sequence": { "sequence": "MAPQKDKKPKKSTWRFHLDLTHPVEDGIFDSGNFEQFLREKVKVNGKTGNLGNVVHIERLKNKITVVSEKQFSKRYLKYLTKKYLKKNNLRDWLRVVASDKETYELRYFQISQDEDGSESED", "length": 122, "header": "tr|A0A3L7IHA0-1|A0A3L7IHA0_CRIGR Isoform 1 of 60S ribosomal protein L22-like 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Rpl22l1 PE=3 SV=1 CANONICAL=A0A3L7IHA0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J731-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHA0/entry#A0A9J7J731-1", "sequence": { "sequence": "MAPKDKKPKKSTWRFHLDLTHPVEDGIFDSGNFEQFLREKVKVNGKTGNLGNVVHIERLKNKITVVSEKQFSKRYLKYLTKKYLKKNNLRDWLRVVASDKETYELRYFQISQDEDGSESED", "length": 121, "header": "tr|A0A9J7J731-1|A0A9J7J731_CRIGR Computationally mapped isoform of 60S ribosomal protein L22-like 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Rpl22l1 PE=3 SV=1 CANONICAL=A0A3L7IHA0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IHA0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHA0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IHA0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHA0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100750612", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750612", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9TQC8-1", "protein_name": "Ribosomal protein L22 like 1", "gene_name": "RPL22L1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "GFFLNCCRLPCGLVEFEKKDKKPKKSTWKFNLDLTHPVEDGIFDSGNFEQFLREKVKVNGKTGNLGNVVHIERFKNKIIVVSEKQFSKRYLKYLTKKYLKKNNLRDWLRVVASDKETYELRYFQISQDEDESESED", "length": 136 }, "evidence": [ { "id": "A0A3L7IHA0", "url": "https://omabrowser.org/oma/group/A0A3L7IHA0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P56628-1", "protein_name": "Large ribosomal subunit protein eL22B", "gene_name": "RPL22B", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAPNTSRKQKVIKTLTVDVSSPTENGVFDPASYSKYLIDHIKVDGAVGNLGNAIEVTEDGSIVTVVSSAKFSGKYLKYLTKKYLKKNQLRDWIRFVSIRQNQYKLVFYQVTPEDADEEEDDE", "length": 122 }, "evidence": [ { "id": "A0A3L7IHA0", "url": "https://omabrowser.org/oma/group/A0A3L7IHA0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q54GK6-1", "protein_name": "Large ribosomal subunit protein eL22B", "gene_name": "rpl22a", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPNVQKTVVKKSHKFVIDCTAPAGKIVDVAAFEKYLHDRIKVDNKVSNLGSNVVISKDKSKIIINTTIPFSKRYLKYLTKKFLKFKQIRDFLRVVATTKNTYELRYFNIGDSESQE", "length": 116 }, "evidence": [ { "id": "A0A3L7IHA0", "url": "https://omabrowser.org/oma/group/A0A3L7IHA0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6P5R6-1", "protein_name": "Ribosomal protein eL22-like", "gene_name": "RPL22L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPQKDRKPKRSTWRFNLDLTHPVEDGIFDSGNFEQFLREKVKVNGKTGNLGNVVHIERFKNKITVVSEKQFSKRYLKYLTKKYLKKNNLRDWLRVVASDKETYELRYFQISQDEDESESED", "length": 122 }, "evidence": [ { "id": "A0A3L7IHA0", "url": "https://omabrowser.org/oma/group/A0A3L7IHA0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D7S7-1", "protein_name": "Ribosomal protein eL22-like 1", "gene_name": "Rpl22l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPQKDKKPKKSTWRFHLDLTHPVEDGIFDSGNFEQFLREKVKVNGKTGNLGNVVHIERLKNKITVVSEKQFSKRYLKYLTKKYLKKNNLRDWLRVVASDKETYELRYFQISQDEDGSESED", "length": 122 }, "evidence": [ { "id": "A0A3L7IHA0", "url": "https://omabrowser.org/oma/group/A0A3L7IHA0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IHA0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHA0" } ], "pmid": "" }, { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IHA0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHA0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IHA0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHA0" } ], "pmid": "" }, { "name": "ribosome", "id": "GO:0005840", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005840", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IHA0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHA0" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IHA0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHA0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cytoplasmic translation", "id": "GO:0002181", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002181", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IHA0", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHA0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7IHB9-1", "uniprot_ac": "A0A3L7IHB9", "uniprot_id": "A0A3L7IHB9_CRIGR", "mass": { "chemical_mass": 46888.0, "monoisotopic_mass": 46888.0 }, "refseq": { "ac": "XP_035306628", "name": "leucine-rich repeat-containing protein 34", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306628" }, "gene_names": [ { "name": "Lrrc34", "type": "recommended", "evidence": [ { "id": "A0A3L7IHB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHB9" } ] }, { "name": "Lrrc34", "type": "synonym", "evidence": [ { "id": "XP_035306628", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306628" } ] } ], "protein_names": [ { "name": "Leucine-rich repeat-containing protein 34", "type": "synonym", "evidence": [ { "id": "A0A3L7IHB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHB9/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat-containing protein 34", "type": "synonym", "evidence": [ { "id": "XP_035306628", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306628" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035306628", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306628" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IHB9", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHB9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Lrrc34", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHB9", "locus": {} } ], "crossref": [ { "id": "100767765", "url": "https://www.ncbi.nlm.nih.gov/gene/100767765", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767765", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767765", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IKNCGMK", "url": "https://omabrowser.org/oma/group/IKNCGMK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7IHB9", "url": "https://www.orthodb.org/?gene=A0A3L7IHB9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24111", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24111", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24111:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24111:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035306628", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306628", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7IHB9", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7IHB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHB9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDKLQVQYCHFCSENLRETNPFVLNILKDLDEEITEKPEKEIILNIAGNNRLRKVQRLTGEDFWLLSKVLRNRSLIIGLDVRYNLISDVGAYYAAKLLQKQPHLTYLNLMFNDIGPDGGELIAKALHKNRTLKYLRMTGNKIENTGGMVFAAMLQINSSLEKLDLGDCDLGLQSVIAFSTVLTQNQAIKGINLNRPILYGEQEESTVHMGHMLKENHFLVELHLCKHDMKNFGMQQLCNALYLNSSLRYLDVSCNKITRDGMVYLADVLKSNTTLEVIDLSFNRIENAGAKYLSETLTSHNRSLKALSVVSNKIEGEGLVALSQSMKTNLILSNIYIWGNKFDEATCVAYSDLMKSGRLNPDNTDVEPYEVDGHVYLAEVSNGLKRHYYWTPTYGNPYDYSSSAGFALVPVGQHL", "length": 415, "header": "tr|A0A3L7IHB9-1|A0A3L7IHB9_CRIGR Isoform 1 of Leucine-rich repeat-containing protein 34 OS=Cricetulus griseus OX=10029 GN=Lrrc34 PE=4 SV=1 CANONICAL=A0A3L7IHB9-1" }, "isoforms": [ { "isoform_ac": "A0A3L7IHB9-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHB9/entry#A0A3L7IHB9-1", "sequence": { "sequence": "MDKLQVQYCHFCSENLRETNPFVLNILKDLDEEITEKPEKEIILNIAGNNRLRKVQRLTGEDFWLLSKVLRNRSLIIGLDVRYNLISDVGAYYAAKLLQKQPHLTYLNLMFNDIGPDGGELIAKALHKNRTLKYLRMTGNKIENTGGMVFAAMLQINSSLEKLDLGDCDLGLQSVIAFSTVLTQNQAIKGINLNRPILYGEQEESTVHMGHMLKENHFLVELHLCKHDMKNFGMQQLCNALYLNSSLRYLDVSCNKITRDGMVYLADVLKSNTTLEVIDLSFNRIENAGAKYLSETLTSHNRSLKALSVVSNKIEGEGLVALSQSMKTNLILSNIYIWGNKFDEATCVAYSDLMKSGRLNPDNTDVEPYEVDGHVYLAEVSNGLKRHYYWTPTYGNPYDYSSSAGFALVPVGQHL", "length": 415, "header": "tr|A0A3L7IHB9-1|A0A3L7IHB9_CRIGR Isoform 1 of Leucine-rich repeat-containing protein 34 OS=Cricetulus griseus OX=10029 GN=Lrrc34 PE=4 SV=1 CANONICAL=A0A3L7IHB9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IHB9", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHB9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IHB9", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHB9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767765", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767765", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1R6M0-1", "protein_name": "Leucine-rich repeat-containing protein 34", "gene_name": "lrrc34", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDDLMERYLSVCAELQQPTHASVLEVLGNNKSSDCCLKLAGNDQPGARLTDDDMLVLTKTLEGNSAIKGLDLRYNCITDKGAVHIAHLIQDSKSLQSLDLMCNDIEADGAEVIAKSLHKNITLKTLRMTGNKIGNQGAMQLATMLQINATLEEVDVSDCDLATQSVIAFAIVLMNNKRICAINVSRPLLFSLQEETTVHMAQMLVVNNTLKELHMGKHDMTDTGVETLCEALKRNISLRYLDLCCNRITRDGAKHLSEVLKQNCSLEILDLSFNCIEDVGAIHLSEAIKLPHSKLKALSVTSNKIRKGGLLSLSAAMRVNSSLTHIYIWGNKHEEPVCEAFSGLMSSGRLLKEHTDVSPYEVDGHVFLAEASHGLRRHYYWTSRYGQDRDSSNSALALMASDSWSQKSHS", "length": 410 }, "evidence": [ { "id": "A0A3L7IHB9", "url": "https://omabrowser.org/oma/group/A0A3L7IHB9/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q4V8D9-1", "protein_name": "Leucine-rich repeat-containing protein 34", "gene_name": "Lrrc34", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEKLQDQYSFLCSENIRKTNPLILNILQKLDEEIEKRPKEKITVNIAGNSRLDSGQRITSEDFWLLSKALRNHPCIGGVDVRYNLIGDVGAYYAAKLLQKQPNITYLNLMFNDIGPEGGELIAKALQKNKTLKYLRMTGNKIENTGGMLFAAMLQMNSSLEKLDLGDCDLGLQSVIAFSTVLTQNKAIKGINLNRPILYGEQEESTVHIGHMSKQNHVLVELHMCKHGMKNYGIQQLCNALHSNSTLRYLDVSCNKITRDGMVFLADVLKSNSTLEVLDLSFNRIENAGAKYLSETLTSHNRSLKALSVVSNKIEGEGLVALSQSMNTNLVLSNIYIWGNKFDEDTCVAYSNLIESGRLKPENTDVEPYVVDEHIYLSEVSNGLKRHYYWTPTYGECYVPSSSAGFALVPVGERL", "length": 415 }, "evidence": [ { "id": "A0A3L7IHB9", "url": "https://omabrowser.org/oma/group/A0A3L7IHB9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IZ02-2", "protein_name": "Leucine-rich repeat-containing protein 34", "gene_name": "LRRC34", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAQPPRPVGERSMGSSREAARAPARSPAWASTQASTPGAALAVQRESPESGLQKHYSNLCMEKSQKINPFILHILQEVDEEIKKGLAAGITLNIAGNNRLVPVERVTGEDFWILSKILKNCLYINGLDVGYNLLCDVGAYYAAKLLQKQLNLIYLNLMFNDIGPEGGELIAKVLHKNRTLKYLRMTGNKIENKGGMFFAAMLQINSSLEKLDLGDCDLGMQSVIAFATVLTQNQAIKAINLNRPILYSEQEESTVHVGRMLKENHCLVALHMCKHDIKNSGIQQLCDALYLNSSLRYLDVSCNKITHDGMVYLADVLKSNTTLEVIDLSFNRIENAGANYLSETLTSHNRSLKALSVVSNNIEGEGLVALSQSMKTNLTFSHIYIWGNKFDEATCIAYSDLIQMGCLKPDNTDVEPFVVDGRVYLAEVSNGLKKHYYWTSTYGESYDHSSNAGFALVPVGQQP", "length": 464 }, "evidence": [ { "id": "A0A3L7IHB9", "url": "https://omabrowser.org/oma/group/A0A3L7IHB9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DAM1-1", "protein_name": "Leucine-rich repeat-containing protein 34", "gene_name": "Lrrc34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKLQAQYCYLCSENIRKTNPFILNILQKLDEEIEKRPKEKFTVNIAGNNRLDSGQRITGEDFWLLSKTLRNQPCISGVDVRYNLIGDVGAFYAAKLLQKQPSITYLNLMFNDIGPEGGELIAKALHKNKTLKYLRMTGNKIENTGGMLFAAMLQMNSSLEKLDLGDCDLGLQCVIAFSTVLTQNQAIKGINLNRPILYGEQEESTVHIGHMLKENHVLVELHMCKHGMKNYGLQQLCNALYLNSSLRYLDVSCNKITRDGMVFLADVLKSNTTLEVLDLSFNRIETAGAKYLSETLTSHNRSLKALSVVSNKIEGEGLVALSQSMKTNLVLSNIYIWGNKFDEDTCVAYSDLIKSGRLKPDNTDVEPYMVDEHIYLSEVSNGLKRHYYWAPTYGETYMPSSSAGFALVPVGEHL", "length": 415 }, "evidence": [ { "id": "A0A3L7IHB9", "url": "https://omabrowser.org/oma/group/A0A3L7IHB9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 157, "end_pos": 159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 244, "end_pos": 246, "annotation": "n_glycosylation_sequon" }, { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 301, "end_pos": 303, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 129, "end_pos": 131 }, { "start_pos": 157, "end_pos": 159 }, { "start_pos": 244, "end_pos": 246 }, { "start_pos": 272, "end_pos": 274 }, { "start_pos": 301, "end_pos": 303 }, { "start_pos": 72, "end_pos": 74 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7IHZ7-1", "uniprot_ac": "A0A3L7IHZ7", "uniprot_id": "A0A3L7IHZ7_CRIGR", "mass": { "chemical_mass": 45781.0, "monoisotopic_mass": 45781.0 }, "refseq": { "ac": "XP_003502933", "name": "arylacetamide deacetylase-like 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502933" }, "gene_names": [ { "name": "LOC100771391", "type": "recommended", "evidence": [ { "id": "A0A3L7IHZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHZ7" } ] }, { "name": "LOC100771391", "type": "synonym", "evidence": [ { "id": "XP_003502933", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502933" } ] } ], "protein_names": [ { "name": "Arylacetamide deacetylase-like 2", "type": "synonym", "evidence": [ { "id": "A0A3L7IHZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHZ7/entry#names_and_taxonomy" } ] }, { "name": "arylacetamide deacetylase-like 2", "type": "synonym", "evidence": [ { "id": "XP_003502933", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502933" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613922.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003502933", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502933" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IHZ7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHZ7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100771391", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHZ7", "locus": {} } ], "crossref": [ { "id": "100771391", "url": "https://www.ncbi.nlm.nih.gov/gene/100771391", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013094", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013094", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033140", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033140", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771391", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771391", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FAYYIYI", "url": "https://omabrowser.org/oma/group/FAYYIYI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7IHZ7", "url": "https://www.orthodb.org/?gene=A0A3L7IHZ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48081", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48081", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48081:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48081:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07859", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07859", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003502933", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502933", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7IHZ7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHZ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7IHZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHZ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRYKTLFFGLSCILFAYYIYTPIPENIEEYWKVRIIDAGTKISSLMGTLFENMGIMKFEDFFNILMKLQNIKPVSDENITVIDTDFSSIPVRLYLPKRKSERQRPAVIYIHGGAFCFGSRKMLPYDFLNRLTANKLDAVVIVPDYRLAPQYPFPAAIEDCVSVVKFFLQDKVLEKYGVDPSRICISGDSSGGTLVAAVTQLLQDDPKYKNKLKAQALIYPGLQAIDTMMPSYQQYQHGPFLSRKVAIKVSCLYLTEDEELPKAILKNEYMPEGSRHLFKFVNWSDFLPAKYKKIHVYREPIIGKLNASYPGLVDSRVSPLIVTDSQLQRLPLTYVLTCEHDILRDDGLIYVTRLRNAGVPVTHDHIEDGIHGAIAFSTAPVYLNLGLRVIDKYISWLEESL", "length": 401, "header": "tr|A0A3L7IHZ7-1|A0A3L7IHZ7_CRIGR Isoform 1 of Arylacetamide deacetylase-like 2 OS=Cricetulus griseus OX=10029 GN=LOC100771391 PE=3 SV=1 CANONICAL=A0A3L7IHZ7-1" }, "isoforms": [ { "isoform_ac": "A0A3L7IHZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHZ7/entry#A0A3L7IHZ7-1", "sequence": { "sequence": "MRYKTLFFGLSCILFAYYIYTPIPENIEEYWKVRIIDAGTKISSLMGTLFENMGIMKFEDFFNILMKLQNIKPVSDENITVIDTDFSSIPVRLYLPKRKSERQRPAVIYIHGGAFCFGSRKMLPYDFLNRLTANKLDAVVIVPDYRLAPQYPFPAAIEDCVSVVKFFLQDKVLEKYGVDPSRICISGDSSGGTLVAAVTQLLQDDPKYKNKLKAQALIYPGLQAIDTMMPSYQQYQHGPFLSRKVAIKVSCLYLTEDEELPKAILKNEYMPEGSRHLFKFVNWSDFLPAKYKKIHVYREPIIGKLNASYPGLVDSRVSPLIVTDSQLQRLPLTYVLTCEHDILRDDGLIYVTRLRNAGVPVTHDHIEDGIHGAIAFSTAPVYLNLGLRVIDKYISWLEESL", "length": 401, "header": "tr|A0A3L7IHZ7-1|A0A3L7IHZ7_CRIGR Isoform 1 of Arylacetamide deacetylase-like 2 OS=Cricetulus griseus OX=10029 GN=LOC100771391 PE=3 SV=1 CANONICAL=A0A3L7IHZ7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IHZ7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHZ7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IHZ7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHZ7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771391", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771391", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "M0R509-1", "protein_name": "AADACL2 family member 2", "gene_name": "Aadacl2fm2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGYKTLCFGLFLILFAYYSYIPMPENIEERWKIQFLDAGMKMLSFMAKMFENLGLIKYEDVLSIFMRVLLTKPVSDENITVIDTDFSDIPVRLYLPKWKSERQRPAVIYIHGGAFTLGSCKIRSYDYLNRWTANKLDAVVVGLDYRLAPQYPFPTAFEDCVLVIKFFLQDTILEKYGVDPTRICISGDSSGGSLATAATQLLQNNPEYKDKIKAQALIYPALQFIDTLMPSHREYEHGPFLSREIGIKLAHLYVTEDIALHQAMQRNEHMPQGSRHLFKFVNWSDFLPEKYKKNHVYNEPTLGKLNVFYPALMDSRLSPLLASDSQLQSLPLTYILTCEHDVLRDEGLIYITRLRNVGVQVAHDHIEEGIHGVMSLIAMPYNLQLGLKVGEKYISWLEKNL", "length": 401 }, "evidence": [ { "id": "A0A3L7IHZ7", "url": "https://omabrowser.org/oma/group/A0A3L7IHZ7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "W4VSP6-1", "protein_name": "AADACL2 family member 2", "gene_name": "Aadacl2fm2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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ester hydrolase activity", "id": "GO:0052689", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052689", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IHZ7", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHZ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3L7IHZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IHZ7" }, { "id": "PF07859", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07859" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha/beta hydrolase fold-3", "eco_id": "ECO_0000259", "start_pos": 107, "end_pos": 258, "start_aa": "Val", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 282, "end_pos": 284 }, { "start_pos": 306, "end_pos": 308 }, { "start_pos": 78, "end_pos": 80 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7IIN5-1", "uniprot_ac": "A0A3L7IIN5", "uniprot_id": "A0A3L7IIN5_CRIGR", "mass": { "chemical_mass": 13634.0, "monoisotopic_mass": 13634.0 }, "refseq": { "ac": "XP_003503274", "name": "transmembrane protein 213", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503274" }, "gene_names": [ { "name": "Tmem213", "type": "recommended", "evidence": [ { "id": "A0A3L7IIN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IIN5" } ] }, { "name": "Tmem213", "type": "synonym", "evidence": [ { "id": "XP_003503274", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503274" } ] } ], "protein_names": [ { "name": "Transmembrane protein 213", "type": "synonym", "evidence": [ { "id": "A0A3L7IIN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IIN5/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 213", "type": "synonym", "evidence": [ { "id": "XP_003503274", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503274" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613951.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003503274", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503274" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IIN5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IIN5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tmem213", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IIN5", "locus": {} } ], "crossref": [ { "id": "100770059", "url": "https://www.ncbi.nlm.nih.gov/gene/100770059", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028121", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028121", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770059", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770059", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NIDFCPQ", "url": "https://omabrowser.org/oma/group/NIDFCPQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7IIN5", "url": "https://www.orthodb.org/?gene=A0A3L7IIN5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR36293", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36293", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR36293:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36293:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15192", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15192", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003503274", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003503274", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7IIN5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IIN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7IIN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IIN5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVPSPRHPCANMVQTGVCSLCLPGYLTSAPQATLLFSLVLASFHSSCGTEASSVNSTLSIHHPDPGTLEQCANVDFCPLASLCCQASVDEYGWIAAAVGWSLWFLTLILLCVDKLMKLTPEEPKHVAA", "length": 128, "header": "tr|A0A3L7IIN5-1|A0A3L7IIN5_CRIGR Isoform 1 of Transmembrane protein 213 OS=Cricetulus griseus OX=10029 GN=Tmem213 PE=4 SV=1 CANONICAL=A0A3L7IIN5-1" }, "isoforms": [ { "isoform_ac": "A0A3L7IIN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IIN5/entry#A0A3L7IIN5-1", "sequence": { "sequence": "MVPSPRHPCANMVQTGVCSLCLPGYLTSAPQATLLFSLVLASFHSSCGTEASSVNSTLSIHHPDPGTLEQCANVDFCPLASLCCQASVDEYGWIAAAVGWSLWFLTLILLCVDKLMKLTPEEPKHVAA", "length": 128, "header": "tr|A0A3L7IIN5-1|A0A3L7IIN5_CRIGR Isoform 1 of Transmembrane protein 213 OS=Cricetulus griseus OX=10029 GN=Tmem213 PE=4 SV=1 CANONICAL=A0A3L7IIN5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IIN5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IIN5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NW_003615192.1) annotated using gene prediction method: Gnomon. 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Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615507.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003512634", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512634" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IIY4", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IIY4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Triml1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IIY4", "locus": {} } ], "crossref": [ { "id": "cd13733", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13733", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100756684", "url": "https://www.ncbi.nlm.nih.gov/gene/100756684", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050143", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050143", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756684", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756684", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GHSFCLM", "url": "https://omabrowser.org/oma/group/GHSFCLM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7IIY4", "url": "https://www.orthodb.org/?gene=A0A3L7IIY4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003512634", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512634", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7IIY4", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IIY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7IIY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IIY4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSIQEKISTVDLMESLREELTCFICLDYFSGPVTTECGHSFCLMCLLKSWEEHNTPLSCPECWRTLGSPHFQANERLGRLASIGRQLRSQVLQNEDEQSSCGRTPGASWVFSDDEQSVINFSTQCHGINRTYFSSEAEEQHKEKLQDIINLLRKKKKEAQTILNHEKERVMLCKEETKTCKQVVVSEYMKMHQFLKEEEQLQLQLLEKEEKENMKKLRENEIQLTQQVRRLGKMIGRIESTSQNLTLEEVRGAMDRCESLLLQCPETTITELSLCRITGMREMLRKFSTDVTLDPATANAYLVLSDDLKSVRHGVTRQQLPDNPERFDQSATVLGAQIFTCGRHYWEVEVGKKTEWEVGICKDSVIRKGNLPKPPGDLFSLIGLKIGDDYSLWVSSPLKGQHVREPVHKVGVFLDYESGHIAFYNVTDETLIYSFPSTSFHEALRPIFSPCLPNEGTNTDPLVICHI", "length": 467, "header": "tr|A0A3L7IIY4-1|A0A3L7IIY4_CRIGR Isoform 1 of Probable E3 ubiquitin-protein ligase TRIML1 OS=Cricetulus griseus OX=10029 GN=Triml1 PE=4 SV=1 CANONICAL=A0A3L7IIY4-1" }, "isoforms": [ { "isoform_ac": "A0A3L7IIY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IIY4/entry#A0A3L7IIY4-1", "sequence": { "sequence": "MSIQEKISTVDLMESLREELTCFICLDYFSGPVTTECGHSFCLMCLLKSWEEHNTPLSCPECWRTLGSPHFQANERLGRLASIGRQLRSQVLQNEDEQSSCGRTPGASWVFSDDEQSVINFSTQCHGINRTYFSSEAEEQHKEKLQDIINLLRKKKKEAQTILNHEKERVMLCKEETKTCKQVVVSEYMKMHQFLKEEEQLQLQLLEKEEKENMKKLRENEIQLTQQVRRLGKMIGRIESTSQNLTLEEVRGAMDRCESLLLQCPETTITELSLCRITGMREMLRKFSTDVTLDPATANAYLVLSDDLKSVRHGVTRQQLPDNPERFDQSATVLGAQIFTCGRHYWEVEVGKKTEWEVGICKDSVIRKGNLPKPPGDLFSLIGLKIGDDYSLWVSSPLKGQHVREPVHKVGVFLDYESGHIAFYNVTDETLIYSFPSTSFHEALRPIFSPCLPNEGTNTDPLVICHI", "length": 467, "header": "tr|A0A3L7IIY4-1|A0A3L7IIY4_CRIGR Isoform 1 of Probable E3 ubiquitin-protein ligase TRIML1 OS=Cricetulus griseus OX=10029 GN=Triml1 PE=4 SV=1 CANONICAL=A0A3L7IIY4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IIY4", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IIY4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IIY4", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IIY4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100756684", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756684", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A221-1", "protein_name": "Tripartite motif family-like 1", "gene_name": "Triml1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVHEKISTADLMENLREELTCFICLDYFSSPVTTECGHSFCLTCLLKSWEEHNTPLSCPECWRTLGAPHFQANERLGRLANIGRQLRCQVLQSEDEQSNSGRTPGPSRVFSDDEQSVINFSPPNHGMNRAYFSSEAEEQHKEKLQDIVNILRKRKKEAQAILNHEKERVMLCKQEETKTCKQVVVSEYMKMHQFLKEEEQLQLQLLEKEEKENVKKLRENEIHLTQQVRRINKMIGRIESICQNLTLESFEEVRGAMDRYESLLFQCPETTITELSLCRITGMREMLRKFSTDITLDPATANAYLLLSDDLKSVRYGGTKQQLPDNPERFDQSATVLGAQIFTCGRHYWEVEVGKKTEWEVGICKDSVNRKGNLPKPPGDLFSLIGLKIGDDYSLWVSSPLKGQHVREPVHKVGVFLDYDSGHIAFYNVTDESLIYSFPPSSFHEALRPIFSPCLPNEGTNTDPLIICHI", "length": 471 }, "evidence": [ { "id": "A0A3L7IIY4", "url": "https://omabrowser.org/oma/group/A0A3L7IIY4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BGW9-1", "protein_name": "Tripartite motif family like 1", "gene_name": "TRIML1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSTADLMENLREELTCFICLDYFTSPVTTECGHSFCLVCLLRSWEEHNTPLSCPECWRTLEIPHFQPNERLGRLAGIGKQLRSQVLQSEGNQGSYERMLAATRMLSDKEPGGHNFLTQGHGVNRMNLSSEAEEHHKEKLQEILDILCKKRKETEVILNHEKERVILCKEETKTCKQVVLSEYAKMHQFLKEEEQLQLQLLEMEERENLKKLRDNEIRLTQQMRSLSKMMEQIESTCQNSIIESFEDVRGILERSEPLLLQCPEAISTELTLCHITGMREMLRKFSTDITLDPATANAYLVLSEDLKSVKHGGIRQQLPDNPERFDQSATVLGTQVFTCGRHYWEVEVGNKTEWEVGICKDSVSRKGNLPKPPGDLFSLIGLKIGDDYSLWVSSPLKGQHVREPVHKVGIFLDYESGHIAFYNVTDESLIYSFPPASFQEALRPIFSPCLPNEGTNTGPLVICSLNHHV", "length": 468 }, "evidence": [ { "id": "A0A3L7IIY4", "url": "https://omabrowser.org/oma/group/A0A3L7IIY4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BVP1-1", "protein_name": "Probable E3 ubiquitin-protein ligase TRIML1", "gene_name": "Triml1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNHEKMSTTDLMENLREELTCFICLDYFSSPVTTECGHSFCLMCLLKSWEEHNTPLSCPECWRTLGAPHFQANERLGRLANIGRQLRSQVLQSEDEQSICGRMPGPSWVFSDDEQSVINVSPPSQGTNKACFSSEAEEQHKEKLQDIINILRKKKKEVQAILNHEKERVMLCKEETKTCKQVVVSEYMKMHQFLKEEEQLQLQLLEREEKANMKKLRENEIQLTQQIRRLGKMIGRIESTCQNLTLESFEEVKGAMDRYESLLFQSPETTITELSLCHITGMREMLRKFSTDITLDPATANAYLLLSEDLKSVRYGGTRQQLPDNPERFDQSATVLGAQIFTCGRHYWEVEVGKKTEWEVGICKDSVNRKGNLPKPPGDLFSLIGLKIGDDYSLWVSSPLKGQHVREPVHKVGVFLDYDSGHIAFYNATDESLIYSFPPTPFHEALRPIFSPCLPNEGTNTDPLIICHI", "length": 470 }, "evidence": [ { "id": "A0A3L7IIY4", "url": "https://omabrowser.org/oma/group/A0A3L7IIY4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N9V2-1", "protein_name": "Probable E3 ubiquitin-protein ligase TRIML1", "gene_name": "TRIML1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSTADLMENLREELTCFICLDYFSSPVTTECGHSFCLVCLLRSWEEHNTPLSCPECWRTLEGPHFQSNERLGRLASIARQLRSQVLQSEDEQGSYGRMPTTAKALSDDEQGGSAFVAQSHGANRVHLSSEAEEHHREKLQEILNLLRVRRKEAQAVLTHEKERVKLCQEETKTCKQVVVSEYMKMHQFLKEEEQLQLQLLEQEEKENMRKLRNNEIKLTQQIRSLSKMIAQIESSSQSSAFESLEEVRGALERSEPLLLQCPEATTTELSLCRITGMKEMLRKFSTEITLDPATANAYLVLSEDLKSVKYGGSRQQLPDNPERFDQSATVLGTQIFTSGRHYWEVEVGNKTEWEVGICKDSVSRKGNLPKPPGDLFSLIGLKIGDDYSLWVSSPLKGQHVREPVCKVGVFLDYESGHIAFYNGTDESLIYSFPQASFQEALRPIFSPCLPNEGTNTDPLTICSLNSHV", "length": 468 }, "evidence": [ { "id": "A0A3L7IIY4", "url": "https://omabrowser.org/oma/group/A0A3L7IIY4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IIY4", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IIY4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IIY4", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IIY4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 244, "end_pos": 246, "annotation": "n_glycosylation_sequon" }, { "start_pos": 425, "end_pos": 427, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3L7IIY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IIY4" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 270, "end_pos": 467, "start_aa": "Thr", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A3L7IIY4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IIY4" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 22, "end_pos": 62, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 120, "end_pos": 122 }, { "start_pos": 129, "end_pos": 131 }, { "start_pos": 244, "end_pos": 246 }, { "start_pos": 425, "end_pos": 427 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7IJN1-1", "uniprot_ac": "A0A3L7IJN1", "uniprot_id": "A0A3L7IJN1_CRIGR", "mass": { "chemical_mass": 45518.0, "monoisotopic_mass": 45518.0 }, "refseq": { "ac": "XP_003511717", "name": "arylacetamide deacetylase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511717" }, "gene_names": [ { "name": "Aadac", "type": "recommended", "evidence": [ { "id": "A0A3L7IJN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IJN1" } ] }, { "name": "Aadac", "type": "synonym", "evidence": [ { "id": "XP_003511717", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511717" } ] } ], "protein_names": [ { "name": "Arylacetamide deacetylase", "type": "synonym", "evidence": [ { "id": "A0A3L7IJN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IJN1/entry#names_and_taxonomy" } ] }, { "name": "arylacetamide deacetylase", "type": "synonym", "evidence": [ { "id": "XP_003511717", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511717" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615192.1) annotated using gene prediction method: Gnomon. 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"https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IJN1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IJN1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "serine hydrolase activity", "id": "GO:0017171", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017171", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IJN1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IJN1" } ], "pmid": "" }, { "name": "triacylglycerol lipase activity", "id": "GO:0004806", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004806", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IJN1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IJN1" } ], "pmid": "" }, { "name": "deacetylase activity", "id": "GO:0019213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019213", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IJN1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IJN1" } ], "pmid": "" } ] } ] }, 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"count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7IK53-1", "uniprot_ac": "A0A3L7IK53", "uniprot_id": "A0A3L7IK53_CRIGR", "mass": { "chemical_mass": 20186.0, "monoisotopic_mass": 20186.0 }, "refseq": { "ac": "XP_003508623", "name": "uncharacterized protein C12orf45 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508623" }, "gene_names": [ { "name": "C1H12orf45", "type": "recommended", "evidence": [ { "id": "A0A3L7IK53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IK53" } ] }, { "name": "C1H12orf45", "type": "synonym", "evidence": [ { "id": "XP_003508623", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508623" } ] } ], "protein_names": [ { "name": "Uncharacterized protein C12orf45 homolog isoform X2", "type": "synonym", "evidence": [ { "id": "A0A3L7IK53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IK53/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C12orf45 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003508623", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508623" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 93 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614555.1) and transcript sequence (JP054145.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003508623.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003508623", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508623" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IK53", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IK53" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "C1H12orf45", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IK53", "locus": {} } ], "crossref": [ { "id": "100771219", "url": "https://www.ncbi.nlm.nih.gov/gene/100771219", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027921", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027921", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771219", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771219", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3L7IK53", "url": "https://www.orthodb.org/?gene=A0A3L7IK53", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28674", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28674", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28674:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28674:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15370", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15370", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003508623", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508623", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7IK53", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IK53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7IK53-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IK53-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELHGERVSSPTASSSSGGRSQVTVSRELLTAGSQDSGSIWDQLLISSKPHPRKTSTLQTVRMQRSPLLDQVQAFLPQMAQANEKLRKEMAVAPVDRFNIENIDGTSGNIIQMDVALFEMNQSDSKEEESSEESSQDGSENSAESEDEDCIPSEVTIDNIKLPHAEGGRGKIEVLDSPASKKKKQ", "length": 185, "header": "tr|A0A3L7IK53-1|A0A3L7IK53_CRIGR Isoform 1 of Uncharacterized protein C12orf45 homolog isoform X2 OS=Cricetulus griseus OX=10029 GN=C1H12orf45 PE=4 SV=1 CANONICAL=A0A3L7IK53-1" }, "isoforms": [ { "isoform_ac": "A0A3L7IK53-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IK53/entry#A0A3L7IK53-1", "sequence": { "sequence": "MELHGERVSSPTASSSSGGRSQVTVSRELLTAGSQDSGSIWDQLLISSKPHPRKTSTLQTVRMQRSPLLDQVQAFLPQMAQANEKLRKEMAVAPVDRFNIENIDGTSGNIIQMDVALFEMNQSDSKEEESSEESSQDGSENSAESEDEDCIPSEVTIDNIKLPHAEGGRGKIEVLDSPASKKKKQ", "length": 185, "header": "tr|A0A3L7IK53-1|A0A3L7IK53_CRIGR Isoform 1 of Uncharacterized protein C12orf45 homolog isoform X2 OS=Cricetulus griseus OX=10029 GN=C1H12orf45 PE=4 SV=1 CANONICAL=A0A3L7IK53-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613748.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003499690", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499690" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IKL6", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IKL6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mboat4", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IKL6", "locus": {} } ], "crossref": [ { "id": "100755071", "url": "https://www.ncbi.nlm.nih.gov/gene/100755071", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049941", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049941", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755071", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755071", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MDWLQLF", "url": "https://omabrowser.org/oma/group/MDWLQLF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7IKL6", "url": "https://www.orthodb.org/?gene=A0A3L7IKL6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13906", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13906", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13906:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13906:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03062", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03062", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003499690", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499690", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7IKL6", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IKL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7IKL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IKL6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDWLQLFFLHPISLYQGAAFPFALLFNYLCIMDSFSTRARYLFLLAGGGVLALAAMGPYALLIFISALCAVALVSLSGPQEVHRLTFSFQMGWQTLCHLGLHYTEYYLQEPAPVRFYIALSSLMLLTQRVTSLSLDIREGKVEAASGGTRNRSSLSVCPSETLPFASYLLFFPALLGGPLCSFQRFRACVERSSSLHPCLSLWALTRRGLQIVGLECLQVALRRVVSAGAGLDDCQQLECIYIMWSTAGLFKLTYYSHWILDDALLHAAGFGSETGQRSGEEGYIPDVDLWTLETTHRISVFARQWNRSTARWLRRLIFRNSQRWPVLQTFAFSAWWHGLHPGQVFGFLCWSVMVEADYLIHTFANLSISFWPLRLLYRAFTWAHTQLIIAYIMLAVEGRSLSFLSRLCCSYNSIFPGVYCVLLFLLVKRKQKCN", "length": 435, "header": "tr|A0A3L7IKL6-1|A0A3L7IKL6_CRIGR Isoform 1 of Ghrelin O-acyltransferase OS=Cricetulus griseus OX=10029 GN=Mboat4 PE=4 SV=1 CANONICAL=A0A3L7IKL6-1" }, "isoforms": [ { "isoform_ac": "A0A3L7IKL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IKL6/entry#A0A3L7IKL6-1", "sequence": { "sequence": "MDWLQLFFLHPISLYQGAAFPFALLFNYLCIMDSFSTRARYLFLLAGGGVLALAAMGPYALLIFISALCAVALVSLSGPQEVHRLTFSFQMGWQTLCHLGLHYTEYYLQEPAPVRFYIALSSLMLLTQRVTSLSLDIREGKVEAASGGTRNRSSLSVCPSETLPFASYLLFFPALLGGPLCSFQRFRACVERSSSLHPCLSLWALTRRGLQIVGLECLQVALRRVVSAGAGLDDCQQLECIYIMWSTAGLFKLTYYSHWILDDALLHAAGFGSETGQRSGEEGYIPDVDLWTLETTHRISVFARQWNRSTARWLRRLIFRNSQRWPVLQTFAFSAWWHGLHPGQVFGFLCWSVMVEADYLIHTFANLSISFWPLRLLYRAFTWAHTQLIIAYIMLAVEGRSLSFLSRLCCSYNSIFPGVYCVLLFLLVKRKQKCN", "length": 435, "header": "tr|A0A3L7IKL6-1|A0A3L7IKL6_CRIGR Isoform 1 of Ghrelin O-acyltransferase OS=Cricetulus griseus OX=10029 GN=Mboat4 PE=4 SV=1 CANONICAL=A0A3L7IKL6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IKL6", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IKL6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IKL6", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IKL6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755071", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755071", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XGU5-1", "protein_name": "Membrane bound O-acyltransferase domain containing 4", "gene_name": "MBOAT4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRWADLLILLPAAWYQLAAFLFAALFHYLCALGHLSLTSRYIFLLAGGCLLAGTAMGSYATLLLIPAVSSVLMFLLVSPAYVHTWVFSLQMCWQTLCHLGLGSLVLESQDTRPAVTLSAIMLLTQKVTSLAMDIHEGTVLPQPGQGLLQRALPLCSYLLFFPALLGGPLCSFSKFQAQVMSLGAVPCPLRAVGWRYLGVLVLQVLRAWLEGWLPCMQGWASMGHMWAQALLFRLAYYSQWVLDEALLEAAGFGAAVEHRDLSGHDLWTLETTHRLSVFSRTWNRSTSLWLRRLVFQRCPVQPLLATFAFSAWWHGLRPGQIFGFLCWAIMVEADYRIHPFLSSRATSCVAKLLYRGTTWVFTQLIIAYIQMAVETESFSMLCLLWTSYNSILPLTYGLVLLLLLLFAQKPKQNRACPGLTRLAG", "length": 424 }, "evidence": [ { "id": "A0A3L7IKL6", "url": "https://omabrowser.org/oma/group/A0A3L7IKL6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "B1Q005-1", "protein_name": "Membrane-bound ghrelin O-acyltransferase MBOAT4", "gene_name": "Mboat4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDWLQFFFLHPVSLYQGAAFPFALLFNYLCITESFPTRARYLFLLAGGGVLALAAMGPYALLIFIPALCAVAMISSLSPQEVHGLTFFFQMGWQTLCHLGLHYKEYYLCEPPPVRFYITLSSLMLLTQRVTSLSLDISEGKVEAAWRGTRSRSSLCEHLWDALPYISYLLFFPALLGGSLCSFQRFQACVQRPRSLYPSISFWALTWRGLQILGLECLKVALRRVVSAGAGLDDCQRLECIYIMWSTAGLFKLTYYSHWILDDSLLHAAGFGSEAGQRPGEERYVPDVDIWTLETTHRISLFARQWNRSTAQWLKRLVFQRSRRWPVLQTFAFSAWWHGLHPGQVFGFLCWSVMVKADYLIHTFANGCIRSWPLRLLYRSLTWAHTQIIIAYVMLAVEGRSFSSLCRLCCSYNSIFPVTYCLLLFLLARRKHKCN", "length": 435 }, "evidence": [ { "id": "A0A3L7IKL6", "url": "https://omabrowser.org/oma/group/A0A3L7IKL6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BAE4-1", "protein_name": "Membrane bound O-acyltransferase domain containing 4", "gene_name": "MBOAT4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDWLQLFFLDPVSLYQGAAFPFALLFNHLCVMDSFSTQARYLFLLAGGGALAVAAMGAFAVLVFIPALCTVVLIHSLGPQDVHRPTFLFQMTWQTLCHLGLHYTEYYLQEAPSTRFCITLSSLMLLTQKITSLSLDIREGKVVAPSGRIPNKNSLSEHLHAALPYLSYLLFFPALLGGPLCSFQRFQARVEGSSSLWSRHSFWALTWRALQILGLESLKVIVSGVVGVGAGLGGCRQLQCVFVLWSTAGLFKLTYYSHWLLDDALLRAAGFGSELGRSPGEEGLLPDADIWTLETTHRIALFARKWNQSTARWLRRLVFQQRRTWPLLQTFLFSAWWHGLHPGQVFGFLCWAVMVEADYLIHAFASVFISSWPMRLLYRALAWAHTQLIIAYIMLAVEARSLSSLWLLWNSYSSVFPTVYCILLLLLAKRKHKCN", "length": 435 }, "evidence": [ { "id": "A0A3L7IKL6", "url": "https://omabrowser.org/oma/group/A0A3L7IKL6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RX63-1", "protein_name": "Membrane bound O-acyltransferase domain containing 4", "gene_name": "MBOAT4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDWLQLFFLHPVLFYQGAAFPFALLFNYLCITDSFSTRARYLFLLAGGGALAVAAMGAFAVLVFVPALGAVVLIHSLGPRHVHRPTFLFQMSWQTLCHLGLHYTEYYLQESPSTRFCITLSSLMLLTQRVTSLSLDIFEGKVEVASEAVGSESSLPKRLWKALPYCSYLLFFPALLGGPLCSFQRFQSRVQGPRSWDPRHSLWALTCGLQILGLECLKVAMRWAVSVGAGLTDCRHLQCVYVMWSMAGLFKLTYYSHWILDESLLQAAGFGSGFGGSTGEESFVPDADIWTLETTHKLSLFTRKWNHSTAQWLRRVFQQGRTWPLLQTFVFSAWWHGLHPGQVFGFLCWAVMVKADYLIHTFAKVSIRSQLMWLLYRTLTWAHTQLIIAYIILAVEARSLSSLWLLCNSYNSVFPMVYCILFFLLAKRKHKCN", "length": 433 }, "evidence": [ { "id": "A0A3L7IKL6", "url": "https://omabrowser.org/oma/group/A0A3L7IKL6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P0C7A3-1", "protein_name": "Membrane-bound ghrelin O-acyltransferase MBOAT4", "gene_name": "Mboat4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWLQLFFLHPLSFYQGAAFPFALLFNYLCILDTFSTRARYLFLLAGGGVLAFAAMGPYSLLIFIPALCAVALVSFLSPQEVHRLTFFFQMGWQTLCHLGLHYTEYYLGEPPPVRFYITLSSLMLLTQRVTSLSLDICEGKVEAPRRGIRSKSSFSEHLWDALPHFSYLLFFPALLGGSLCSFRRFQACVQRSSSLYPSISFRALTWRGLQILGLECLKVALRSAVSAGAGLDDCQRLECIYLMWSTAWLFKLTYYSHWILDDSLLHAAGFGAEAGQGPGEEGYVPDVDIWTLETTHRISLFARQWNRSTALWLRRLVFRKSRRWPLLQTFAFSAWWHGLHPGQVFGFLCWSVMVKADYLIHTFANVCIRSWPLRLLYRALTWAHTQLIIAYIMLAVEGRSLSSLCQLCCSYNSLFPVMYGLLLFLLAERKDKRN", "length": 435 }, "evidence": [ { "id": "A0A3L7IKL6", "url": "https://omabrowser.org/oma/group/A0A3L7IKL6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96T53-1", "protein_name": "Membrane-bound ghrelin O-acyltransferase MBOAT4", "gene_name": "MBOAT4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEWLWLFFLHPISFYQGAAFPFALLFNYLCIMDSFSTRARYLFLLTGGGALAVAAMGSYAVLVFTPAVCAVALLCSLAPQQVHRWTFCFQMSWQTLCHLGLHYTEYYLHEPPSVRFCITLSSLMLLTQRVTSLSLDICEGKVKAASGGFRSRSSLSEHVCKALPYFSYLLFFPALLGGSLCSFQRFQARVQGSSALHPRHSFWALSWRGLQILGLECLNVAVSRVVDAGAGLTDCQQFECIYVVWTTAGLFKLTYYSHWILDDSLLHAAGFGPELGQSPGEEGYVPDADIWTLERTHRISVFSRKWNQSTARWLRRLVFQHSRAWPLLQTFAFSAWWHGLHPGQVFGFVCWAVMVEADYLIHSFANEFIRSWPMRLFYRTLTWAHTQLIIAYIMLAVEVRSLSSLWLLCNSYNSVFPMVYCILLLLLAKRKHKCN", "length": 435 }, "evidence": [ { "id": "A0A3L7IKL6", "url": "https://omabrowser.org/oma/group/A0A3L7IKL6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IKL6", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IKL6" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IKL6", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IKL6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine O-acyltransferase activity", "id": "GO:0016412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016412", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IKL6", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IKL6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "lipid modification", "id": "GO:0030258", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030258", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IKL6", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IKL6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 366, "end_pos": 368, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 151, "end_pos": 153 }, { "start_pos": 307, "end_pos": 309 }, { "start_pos": 366, "end_pos": 368 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7IL73-1", "uniprot_ac": "A0A3L7IL73", "uniprot_id": "A0A3L7IL73_CRIGR", "mass": { "chemical_mass": 8549.0, "monoisotopic_mass": 8549.0 }, "refseq": { "ac": "XP_003505913", "name": "surfactant-associated protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505913" }, "gene_names": [ { "name": "Sfta2", "type": "recommended", "evidence": [ { "id": "A0A3L7IL73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IL73" } ] }, { "name": "Sfta2", "type": "synonym", "evidence": [ { "id": "XP_003505913", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505913" } ] } ], "protein_names": [ { "name": "Surfactant-associated protein 2", "type": "synonym", "evidence": [ { "id": "A0A3L7IL73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IL73/entry#names_and_taxonomy" } ] }, { "name": "surfactant-associated protein 2", "type": "synonym", "evidence": [ { "id": "XP_003505913", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505913" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614196.1) annotated using gene prediction method: Gnomon. 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"title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7INK5-1", "uniprot_ac": "A0A3L7INK5", "uniprot_id": "A0A3L7INK5_CRIGR", "mass": { "chemical_mass": 49270.0, "monoisotopic_mass": 49270.0 }, "refseq": { "ac": "XP_007638757", "name": "major facilitator superfamily domain-containing protein 9 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638757" }, "gene_names": [ { "name": "Mfsd9", "type": "recommended", "evidence": [ { "id": "A0A3L7INK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7INK5" } ] }, { "name": "Mfsd9", "type": "synonym", "evidence": [ { "id": "XP_007638757", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638757" } ] } ], "protein_names": [ { "name": "Major facilitator superfamily domain-containing protein 9 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A3L7INK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7INK5/entry#names_and_taxonomy" } ] }, { "name": "major facilitator superfamily domain-containing protein 9 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007638757", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638757" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 133 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613754.1) and transcript sequence (IACG01100652.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007638757.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007638757", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638757" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7INK5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7INK5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mfsd9", "url": "https://www.uniprot.org/uniprotkb/A0A3L7INK5", "locus": {} } ], "crossref": [ { "id": "cd17390", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17390", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100760470", "url": "https://www.ncbi.nlm.nih.gov/gene/100760470", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001958", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001958", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760470", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760470", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3L7INK5", "url": "https://www.orthodb.org/?gene=A0A3L7INK5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23504", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23504", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23504:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23504:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007638757", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638757", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7INK5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7INK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7INK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7INK5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J5C8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5C8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J5C8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J5C8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALGLRGRGASGKGLASETPATATAPSGAAGSRRFLLCLYLVGFLDLFGVSMVVPLLSLHVKSLGVSPVVAGVVGSSYGALQLFSSTFVGCWSDVVGRRSSLLVCILLSALGYLLLGVSTNVFLFTLARVPVGVFKHTLSISRALLSDLVTEKERPLVLGQFNTASGVGFILGPMVGGYLTELDGGFYMTAFICSSVFLLNAGLVWLLPWRETNLHSAENGWSLDQKHATAPRKSEGTLQGAATTPKVRWSEKKVQRPWVEVVSALKDMKSLIFSTLWDIFLVRLLMGVAVMLYYSNFVLALEERFGVRPKTTGYLISYTSALGTLAGFAVGPILRLYKHNSYMVLLHSSALTCLLLLLYSVASTMHVVVFSSTLLSFSTSIGRTCVTDLQLSAGGAQASGTVIGVGQSVTAVGRIIAPLLSGVAQEISPCGPPSLGAALALVAILIMSLNKPHSSGDGSKVLKRE", "length": 466, "header": "tr|A0A3L7INK5-1|A0A3L7INK5_CRIGR Isoform 1 of Major facilitator superfamily domain-containing protein 9 isoform X2 OS=Cricetulus griseus OX=10029 GN=Mfsd9 PE=4 SV=1 CANONICAL=A0A3L7INK5-1" }, "isoforms": [ { "isoform_ac": "A0A3L7INK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7INK5/entry#A0A3L7INK5-1", "sequence": { "sequence": "MALGLRGRGASGKGLASETPATATAPSGAAGSRRFLLCLYLVGFLDLFGVSMVVPLLSLHVKSLGVSPVVAGVVGSSYGALQLFSSTFVGCWSDVVGRRSSLLVCILLSALGYLLLGVSTNVFLFTLARVPVGVFKHTLSISRALLSDLVTEKERPLVLGQFNTASGVGFILGPMVGGYLTELDGGFYMTAFICSSVFLLNAGLVWLLPWRETNLHSAENGWSLDQKHATAPRKSEGTLQGAATTPKVRWSEKKVQRPWVEVVSALKDMKSLIFSTLWDIFLVRLLMGVAVMLYYSNFVLALEERFGVRPKTTGYLISYTSALGTLAGFAVGPILRLYKHNSYMVLLHSSALTCLLLLLYSVASTMHVVVFSSTLLSFSTSIGRTCVTDLQLSAGGAQASGTVIGVGQSVTAVGRIIAPLLSGVAQEISPCGPPSLGAALALVAILIMSLNKPHSSGDGSKVLKRE", "length": 466, "header": "tr|A0A3L7INK5-1|A0A3L7INK5_CRIGR Isoform 1 of Major facilitator superfamily domain-containing protein 9 isoform X2 OS=Cricetulus griseus OX=10029 GN=Mfsd9 PE=4 SV=1 CANONICAL=A0A3L7INK5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J5C8-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7INK5/entry#A0A9J7J5C8-1", "sequence": { "sequence": "MALGLRGRGASGKGLASETPATATAPSGAAGSRRFLLCLYLDLFGVSMVVPLLSLHVKSLGVSPVVAGVVGSSYGALQLFSSTFVGCWSDVVGRRSSLLVCILLSALGYLLLGVSTNVFLFTLARVPVGVFKHTLSISRALLSDLVTEKERPLVLGQFNTASGVGFILGPMVGGYLTELDGGFYMTAFICSSVFLLNAGLVWLLPWRETNLHSAENGWSLDQKHATAPRKSEGTLQGAATTPKVRWSEKKVQRPWVEVVSALKDMKSLIFSTLWDIFLVRLLMGVAVMLYYSNFVLALEERFGVRPKTTGYLISYTSALGTLAGFAVGPILRLYKHNSYMVLLHSSALTCLLLLLYSVASTMHVVVFSSTLLSFSTSIGRTCVTDLQLSAGGAQASGTVIGVGQSVTAVGRIIAPLLSGVAQEISPCGPPSLGAALALVAILIMSLNKPHSSGDGSKVLKRE", "length": 462, "header": "tr|A0A9J7J5C8-1|A0A9J7J5C8_CRIGR Computationally mapped isoform of Major facilitator superfamily domain-containing protein 9 isoform X3 OS=Cricetulus griseus OX=10029 GN=Mfsd9 PE=4 SV=1 CANONICAL=A0A3L7INK5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7INK5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7INK5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7INK5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7INK5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760470", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760470", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7INK5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7INK5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7INK5", "url": "https://www.uniprot.org/uniprotkb/A0A3L7INK5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3L7INK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7INK5" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 456, "start_aa": "Phe", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A3L7INZ5-1", "uniprot_ac": "A0A3L7INZ5", "uniprot_id": "A0A3L7INZ5_CRIGR", "mass": { "chemical_mass": 34013.0, "monoisotopic_mass": 34013.0 }, "refseq": { "ac": "XP_035309275", "name": "uncharacterized protein CCDC198", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309275" }, "gene_names": [ { "name": "Ccdc198", "type": "recommended", "evidence": [ { "id": "A0A3L7INZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7INZ5" } ] }, { "name": "Ccdc198", "type": "synonym", "evidence": [ { "id": "XP_035309275", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309275" } ] } ], "protein_names": [ { "name": "Uncharacterized protein CCDC198", "type": "synonym", "evidence": [ { "id": "A0A3L7INZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7INZ5/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein CCDC198", "type": "synonym", "evidence": [ { "id": "XP_035309275", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309275" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027242303", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027242303" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IP49", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IP49" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100757237", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IP49", "locus": {} } ], "crossref": [ { "id": "cd15916", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15916", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100757237", "url": "https://www.ncbi.nlm.nih.gov/gene/100757237", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757237", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757237", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A3L7IP49", "url": "https://www.orthodb.org/?gene=A0A3L7IP49", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027242303", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027242303", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7IP49", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IP49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7IP49-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IP49-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRNRNTSLDTVVTDFILLGLAHPPNLRTFLFLVFFLIYILTQLGNLLILLTVWADPKLHARPMYILLGVLSFLDMWLSSVIVPRLILNFTPASKAIPFGGCVAQLYFFHFLGSTQCFLYTLMAYDRYLAICQPLRYPVLMNGKLCTILVAGAWAAGSIHGSIQVTLTFRLPYCGPNQIDYFICDIPAVLRLACADTTVNKLVTFVDIGVVAASCFMLILLSYANIVHAILKIRTADGRRRAFSTCGSHLTVVTVYYVPCIFIYLRAGSKSPLDGAVAVFYTVVTPLLNPLIYTLRNQEVKSALKRLRAGRGGNVDGDK", "length": 319, "header": "tr|A0A3L7IP49-1|A0A3L7IP49_CRIGR Isoform 1 of Olfactory receptor 10G2 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100757237 PE=3 SV=1 CANONICAL=A0A3L7IP49-1" }, "isoforms": [ { "isoform_ac": "A0A3L7IP49-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IP49/entry#A0A3L7IP49-1", "sequence": { "sequence": "MRRNRNTSLDTVVTDFILLGLAHPPNLRTFLFLVFFLIYILTQLGNLLILLTVWADPKLHARPMYILLGVLSFLDMWLSSVIVPRLILNFTPASKAIPFGGCVAQLYFFHFLGSTQCFLYTLMAYDRYLAICQPLRYPVLMNGKLCTILVAGAWAAGSIHGSIQVTLTFRLPYCGPNQIDYFICDIPAVLRLACADTTVNKLVTFVDIGVVAASCFMLILLSYANIVHAILKIRTADGRRRAFSTCGSHLTVVTVYYVPCIFIYLRAGSKSPLDGAVAVFYTVVTPLLNPLIYTLRNQEVKSALKRLRAGRGGNVDGDK", "length": 319, "header": "tr|A0A3L7IP49-1|A0A3L7IP49_CRIGR Isoform 1 of Olfactory receptor 10G2 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100757237 PE=3 SV=1 CANONICAL=A0A3L7IP49-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IRI2", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IRI2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773439", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773439", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IRI2", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IRI2" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IRI2", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IRI2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7IRI2", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IRI2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A3L7IRI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A3L7IRI2" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 45, "end_pos": 293, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2L7F5-1", "uniprot_ac": "A0A8C2L7F5", "uniprot_id": "A0A8C2L7F5_CRIGR", "mass": { "chemical_mass": 67046.0, "monoisotopic_mass": 67046.0 }, "refseq": { "ac": "XP_003508591", "name": "leucine-rich repeat-containing protein 29 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508591" }, "gene_names": [ { "name": "Lrrc29", "type": "recommended", "evidence": [ { "id": "A0A8C2L7F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7F5" } ] }, { "name": "Lrrc29", "type": "synonym", "evidence": [ { "id": "XP_003508591", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508591" } ] } ], "protein_names": [ { "name": "Leucine-rich repeat-containing protein 29 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8C2L7F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7F5/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat-containing protein 29 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003508591", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508591" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614552.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003508591.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003508591", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508591" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2L7F5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7F5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Lrrc29", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7F5", "locus": {} } ], "crossref": [ { "id": "100760321", "url": "https://www.ncbi.nlm.nih.gov/gene/100760321", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006553", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006553", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057207", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057207", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760321", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760321", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2L7F5", "url": "https://www.orthodb.org/?gene=A0A8C2L7F5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FJ24", "url": "https://www.orthodb.org/?gene=A0A9J7FJ24", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FJP3", "url": "https://www.orthodb.org/?gene=A0A9J7FJP3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FMP0", "url": "https://www.orthodb.org/?gene=A0A9J7FMP0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13318", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13318", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13318:SF169", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13318:SF169", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25372", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25372", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003508591", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508591", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2L7F5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7F5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2L7F5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7F5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FJ24", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FJ24-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJ24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FJP3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FJP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FJP3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FMP0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FMP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FMP0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADSLPLEMLTYILSFLPLSDQKEASLVNRAWYYAAQNALRETNVRYNIPVSSASLSAIKNLGLRGISCISLTNLDGSPASHQVLQSVAYHLGPHLESLCLGGGSPTEASFLALILGCPVLRTLDLSGCNSLFTSGTLLAQPETAQCVRKALSGLRDLNLAGLRDLTDLSFNHLSSCFPSLERLSLAYCHITFELGPTWGSISPQETSPSQLSFHNLLQFVKERAGRLRALDLSGTGLPPEALQALGQVTGLQLEELSLHSCRDLSSEAVATLCRQQPGLTSLDLSGCSELTDRALLAVSRGLQHLRHLSLRKLQRLTDAGCTALGSLHELQSLDMAECCLVSGRELAQVLGSVHRAPPALTSLRLAYCSSLKDASVLTMIPALGPSLKVLDLSSCVALTNQTMKAICTYLIHLSVLRLAWCKELQDWGLLGLKDPSEEPMLSPQLHQEVENQAPDPQEPNSEPQGPSLLMLQGLQELDLTACSKLTDASLAKVLQFPQLRQLSLSLLPALTDMGLAAVARGCPSLERLALSHCSHLSDEGWAQAARFWPRLKHLNLSSCSQLTEQTLDTIGQTCKQLRVLDVAMCPGINMAAVRQFQAQLPQVTCIQSRFVGGADLTLTL", "length": 621, "header": "tr|A0A8C2L7F5-1|A0A8C2L7F5_CRIGR Isoform 1 of Leucine-rich repeat-containing protein 29 isoform X1 OS=Cricetulus griseus OX=10029 GN=Lrrc29 PE=4 SV=1 CANONICAL=A0A8C2L7F5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2L7F5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7F5/entry#A0A8C2L7F5-1", "sequence": { "sequence": "MADSLPLEMLTYILSFLPLSDQKEASLVNRAWYYAAQNALRETNVRYNIPVSSASLSAIKNLGLRGISCISLTNLDGSPASHQVLQSVAYHLGPHLESLCLGGGSPTEASFLALILGCPVLRTLDLSGCNSLFTSGTLLAQPETAQCVRKALSGLRDLNLAGLRDLTDLSFNHLSSCFPSLERLSLAYCHITFELGPTWGSISPQETSPSQLSFHNLLQFVKERAGRLRALDLSGTGLPPEALQALGQVTGLQLEELSLHSCRDLSSEAVATLCRQQPGLTSLDLSGCSELTDRALLAVSRGLQHLRHLSLRKLQRLTDAGCTALGSLHELQSLDMAECCLVSGRELAQVLGSVHRAPPALTSLRLAYCSSLKDASVLTMIPALGPSLKVLDLSSCVALTNQTMKAICTYLIHLSVLRLAWCKELQDWGLLGLKDPSEEPMLSPQLHQEVENQAPDPQEPNSEPQGPSLLMLQGLQELDLTACSKLTDASLAKVLQFPQLRQLSLSLLPALTDMGLAAVARGCPSLERLALSHCSHLSDEGWAQAARFWPRLKHLNLSSCSQLTEQTLDTIGQTCKQLRVLDVAMCPGINMAAVRQFQAQLPQVTCIQSRFVGGADLTLTL", "length": 621, "header": "tr|A0A8C2L7F5-1|A0A8C2L7F5_CRIGR Isoform 1 of Leucine-rich repeat-containing protein 29 isoform X1 OS=Cricetulus griseus OX=10029 GN=Lrrc29 PE=4 SV=1 CANONICAL=A0A8C2L7F5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FJ24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7F5/entry#A0A9J7FJ24-1", "sequence": { "sequence": "MAECCLVSGRELAQVLGSVHRAPPALTSLRLAYCSSLKDASVLTMIPALGPSLKVLDLSSCVALTNQTMKAICTYLIHLSVLRLAWCKELQDWGLLGLKDPSEEPMLSPQLHQEVENQAPDPQEPNSEPQGPSLLMLQGLQELDLTACSKLTDASLAKVLQFPQLRQLSLSLLPALTDMGLAAVARGCPSLERLALSHCSHLSDEGWAQAARFWPRLKHLNLSSCSQLTEQTLDTIGQTCKQLRVLDVAMCPGINMAAVRQFQAQLPQVTCIQSRFVGGADLTLTL", "length": 286, "header": "tr|A0A9J7FJ24-1|A0A9J7FJ24_CRIGR Computationally mapped isoform of Leucine-rich repeat-containing protein 29 isoform X4 OS=Cricetulus griseus OX=10029 GN=Lrrc29 PE=4 SV=1 CANONICAL=A0A8C2L7F5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FJP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7F5/entry#A0A9J7FJP3-1", "sequence": { "sequence": "MADSLPLEMLTYILSFLPLSDQKEASLVNRAWYYAAQNALRETNVRYNIPVSSASLSAIKNLGLRGISCISLTNLDGSPASHQVLQSVAYHLGPHLESLCLGGGSPTEASFLALILGCPVLRTLDLSGCNSLFTSGTLLAQPETAQCVRKALSGLRDLNLAGLRDLTDLSFNHLSSCFPSLERLSLAYCHITFELGPTWGSISPQETSPSQLSFHNLLQFVKERAGRLRALDLSGTGLPPEALQALGQVTGLQLEELSLHSCRDLSSEAVATLCRQQPGLTSLDLSGCSELTDRALLAVSRGLQHLRHLSLRKLQRLTDAGCTALGSLHELQSLDMAECCLVSGRELAQVLGSVHRAPPALTSLRLAYCSSLKDASVLTMIPALGPSLKVLDLSSCVALTNQTMKAICTYLIHLSVLRLAWCKELQDWGLLGLKDPSEEPMLSPQLHQEVENQAPDPQEPNSEPQGPSLLMLQGLQELDLTACSKLTDASLAKNQGTWKGPRL", "length": 503, "header": "tr|A0A9J7FJP3-1|A0A9J7FJP3_CRIGR Computationally mapped isoform of Leucine-rich repeat-containing protein 29 isoform X3 OS=Cricetulus griseus OX=10029 GN=Lrrc29 PE=4 SV=1 CANONICAL=A0A8C2L7F5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FMP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7F5/entry#A0A9J7FMP0-1", "sequence": { "sequence": "MLTYILSFLPLSDQKEASLVNRAWYYAAQNALRETNVRYNIPVSSASLSAIKNLGLRGISCISLTNLDGSPASHQVLQSVAYHLGPHLESLCLGGGSPTEASFLALILGCPVLRTLDLSGCNSLFTSGTLLAQPETAQCVRKALSGLRDLNLAGLRDLTDLSFNHLSSCFPSLERLSLAYCHITFELGPTWGSISPQETSPSQLSFHNLLQFVKERAGRLRALDLSGTGLPPEALQALGQVTGLQLEELSLHSCRDLSSEAVATLCRQQPGLTSLDLSGCSELTDRALLAVSRGLQHLRHLSLRKLQRLTDAGCTALGSLHELQSLDMAECCLVSGRELAQVLGSVHRAPPALTSLRLAYCSSLKDASVLTMIPALGPSLKVLDLSSCVALTNQTMKAICTYLIHLSVLRLAWCKELQDWGLLGLKDPSEEPMLSPQLHQEVENQAPDPQEPNSEPQGPSLLMLQGLQELDLTACSKLTDASLAKVLQFPQLRQLSLSLLPALTDMGLAAVARGCPSLERLALSHCSHLSDEGWAQAARFWPRLKHLNLSSCSQLTEQTLDTIGQTCKQLRVLDVAMCPGINMAAVRQFQAQLPQVTCIQSRFVGGADLTLTL", "length": 613, "header": "tr|A0A9J7FMP0-1|A0A9J7FMP0_CRIGR Computationally mapped isoform of Leucine-rich repeat-containing protein 29 isoform X2 OS=Cricetulus griseus OX=10029 GN=Lrrc29 PE=4 SV=1 CANONICAL=A0A8C2L7F5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 198, "start_aa": "Thr", "end_pos": 198, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr198", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2L7F5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7F5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760321", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760321", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2L7F5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7F5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": 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}, { "id": "IPR057321", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057321", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760011", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760011", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2L7R6", "url": "https://www.orthodb.org/?gene=A0A8C2L7R6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12619", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12619", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12619:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12619:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF25340", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25340", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035306954", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306954", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2L7R6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2L7R6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNWAAFGGPEFFIPGGMQMEASCPLGRNFTEWYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKREVTKQTVAYSPRSKLGTLLPDFPNVKDLNLPASLPEEKVSTFIMMYRTHCQRILDTVIRANFDEVQSFLLHFWQGMPPHMLPVLGSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLDEWLKVALHDLPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLNSITKQTLYTMEDSRDEHRRLIIQLYQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKKQGSLKKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANELMRAMKGEGSSTAEVQEEIILTEAAPPTPSSVPSFSPAKSATSVEVPPPSSPASNPSPEYTGLSTTGAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRSTHMPSSSVTHRIPVYSHREEHGYTGSYNYGSYGNQHPHPMQSQYPALPHDTAISGPLHYSPYHRSSAQYPFNSPTSRMEPCLMSSTPRLHPTPVTPRWPEVPTANACYTSPSVHSTRYGNSSDMYTPLTTRRNSEYEHMQHFPGFAYINGEASTGWAK", "length": 642, "header": "tr|A0A8C2L7R6-1|A0A8C2L7R6_CRIGR Isoform 1 of Transcription factor RFX4 OS=Cricetulus griseus OX=10029 GN=Rfx4 PE=4 SV=1 CANONICAL=A0A8C2L7R6-1" }, "isoforms": [ { "isoform_ac": "A0A8C2L7R6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R6/entry#A0A8C2L7R6-1", "sequence": { "sequence": "MNWAAFGGPEFFIPGGMQMEASCPLGRNFTEWYHYYGIAVKESSQYYDVMYSKKGAAWVSETGKREVTKQTVAYSPRSKLGTLLPDFPNVKDLNLPASLPEEKVSTFIMMYRTHCQRILDTVIRANFDEVQSFLLHFWQGMPPHMLPVLGSSTVVNIVGVCDSILYKAISGVLMPTVLQALPDSLTQVIRKFAKQLDEWLKVALHDLPENLRNIKFELSRRFSQILRRQTSLNHLCQASRTVIHSADITFQMLEDWRNVDLNSITKQTLYTMEDSRDEHRRLIIQLYQEFDHLLEEQSPIESYIEWLDTMVDRCVVKVAAKKQGSLKKVAQQFLLMWSCFGTRVIRDMTLHSAPSFGSFHLIHLMFDDYVLYLLESLHCQERANELMRAMKGEGSSTAEVQEEIILTEAAPPTPSSVPSFSPAKSATSVEVPPPSSPASNPSPEYTGLSTTGAMQSYTWSLTYTVTTAAGSPAENSQQLPCMRSTHMPSSSVTHRIPVYSHREEHGYTGSYNYGSYGNQHPHPMQSQYPALPHDTAISGPLHYSPYHRSSAQYPFNSPTSRMEPCLMSSTPRLHPTPVTPRWPEVPTANACYTSPSVHSTRYGNSSDMYTPLTTRRNSEYEHMQHFPGFAYINGEASTGWAK", "length": 642, "header": "tr|A0A8C2L7R6-1|A0A8C2L7R6_CRIGR Isoform 1 of Transcription factor RFX4 OS=Cricetulus griseus OX=10029 GN=Rfx4 PE=4 SV=1 CANONICAL=A0A8C2L7R6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 413, "start_aa": "Thr", "end_pos": 413, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr413", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 579, "start_aa": "Thr", "end_pos": 579, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr579", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2L7R6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2L7R6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760011", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760011", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2L7R6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2L7R6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 28, "end_pos": 30, "annotation": "n_glycosylation_sequon" }, { "start_pos": 604, "end_pos": 606, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2L7R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7R6" }, { "id": "PF25340", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25340" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RFX1-4/6/8-like BCD", "eco_id": "ECO_0000259", "start_pos": 107, "end_pos": 380, "start_aa": "Phe", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 413, 579 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 28, "end_pos": 30 }, { "start_pos": 604, "end_pos": 606 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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"graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2L7S0-1", "uniprot_ac": "A0A8C2L7S0", "uniprot_id": "A0A8C2L7S0_CRIGR", "mass": { "chemical_mass": 151675.0, "monoisotopic_mass": 151675.0 }, "refseq": { "ac": "XP_027247371", "name": "zinc finger protein 804B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247371" }, "gene_names": [ { "name": "Znf804b", "type": "recommended", "evidence": [ { "id": "A0A8C2L7S0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7S0" } ] }, { "name": "Znf804b", "type": "synonym", "evidence": [ { "id": "XP_027247371", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247371" } ] } ], "protein_names": [ { "name": "Zinc finger protein 804B", "type": "synonym", "evidence": [ { "id": "A0A8C2L7S0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7S0/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 804B", "type": "synonym", "evidence": [ { "id": "XP_027247371", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247371" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027247371", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247371" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2L7S0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7S0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Znf804b", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7S0", "locus": {} } ], "crossref": [ { "id": "100765814", "url": "https://www.ncbi.nlm.nih.gov/gene/100765814", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765814", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765814", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2L7S0", "url": "https://www.orthodb.org/?gene=A0A8C2L7S0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17614", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17614", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17614:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17614:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27597", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27597", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027247371", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247371", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2L7S0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7S0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2L7S0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L7S0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007649426", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649426" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2L8E4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L8E4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Heatr6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L8E4", "locus": {} } ], "crossref": [ { "id": "100773538", "url": "https://www.ncbi.nlm.nih.gov/gene/100773538", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] 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"PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13366:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13366:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13251", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13251", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007649426", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649426", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2L8E4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L8E4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2L8E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L8E4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAVQVASSLPCGQPRAAPREQSSEDDGFRRLSARLRALQPDDSTVSRMEIHLLFDQLISENYSEGGGVAPEDVGSLLVRACQLVPLNQNHLVSKVSQLIHHLLNRLQVVVDEQNLDFLLTYTISAIHQCCSWTHMEILQALATLVYCNGSKCQKHLPDLLGKSGLLMKLSDSSHPDPEVRRAAVHCMANLCLSVPGQPCLEESYQNICFQAFLTILRSPKSPDMDDITFCMLLQNALKGTQSLLNGGKMRMTQTEHLGALLAVLKKVMFHGLPGLNIEMPAVLYPTPLPQYDGRSPAKPQQPEPSAARPSANKKKKHKVKPKKPQGEKEEEDESSEVEVAPGLSTSRVNTCGEIAWCSSPWGSQSLPVDGSRAAGREQASWPFASSWKRVSSSESDYSDSEGGMQGKTRSYQAKVRQGALACFLSTIKSIEKKVLYGYWSAFVPDTPELGSPQSVSLMTLTLKDPSPKTRACALQVLSAILEGSKQFLSVAEDTTDHRMAFTPFSVTIASSIRELHRCLLLALVAESSSQTITQIIKCLANLVSNAPYNRLKLSLLTKVWNHIKPYIRHKDVNVRVSSLTLLGAIVSTHAPLPEVQLLLQQPCSSGLSSSNSATPHLSTPDCWDRVPGGSSLEEVSVSSPKASAEPCWLIRLCISTVVLPKEDSCSGSDAGSAVGSTYEPCPMRLEALQVLAHLARGYFSMAQLYLMELGEVICKCMGEANPSIQLHSVKLLEELGTGLIQQYKPDSNMAPEQRVPIYMVVMFWTAMLNGPLPRALQSSEHPTLQASACDALSSILPEAFSSLPNDKQILCITMLLGLNDNKNHLVKAATSRALGVYVLFPCLRQDVIFVADTANAILMSLQDKSLNVRAKAAWSLGNLTDTLIVNMDTPDPSFQDEFSGLLLLKMLQSAIHASTDKDKVKSNAVRALGNLLHFLQPTHIERPRFAEIIEESIQALISTVVNEAAMKVRWNACYAIGNVFKNPALPLGSAPWTSQAYKALTSVVMSCKNFKVRIRSAAALSIPGKRAQYGSLEQFAQIWNALVTALQKSEDTTDFLEFKYCASLRTHICQALLHLLSLASASDFPCIQDSLERNGDMIQFYILQFLKSGVEGDDPGAVHTPQERDQMVRVALKHIHSVQALPGDTAKRVIVIFLEDTLAIHCDSSGGQVALLGSSDQ", "length": 1178, "header": "tr|A0A8C2L8E4-1|A0A8C2L8E4_CRIGR Isoform 1 of HEAT repeat-containing protein 6 OS=Cricetulus griseus OX=10029 GN=Heatr6 PE=4 SV=1 CANONICAL=A0A8C2L8E4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2L8E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L8E4/entry#A0A8C2L8E4-1", "sequence": { "sequence": "MAAVQVASSLPCGQPRAAPREQSSEDDGFRRLSARLRALQPDDSTVSRMEIHLLFDQLISENYSEGGGVAPEDVGSLLVRACQLVPLNQNHLVSKVSQLIHHLLNRLQVVVDEQNLDFLLTYTISAIHQCCSWTHMEILQALATLVYCNGSKCQKHLPDLLGKSGLLMKLSDSSHPDPEVRRAAVHCMANLCLSVPGQPCLEESYQNICFQAFLTILRSPKSPDMDDITFCMLLQNALKGTQSLLNGGKMRMTQTEHLGALLAVLKKVMFHGLPGLNIEMPAVLYPTPLPQYDGRSPAKPQQPEPSAARPSANKKKKHKVKPKKPQGEKEEEDESSEVEVAPGLSTSRVNTCGEIAWCSSPWGSQSLPVDGSRAAGREQASWPFASSWKRVSSSESDYSDSEGGMQGKTRSYQAKVRQGALACFLSTIKSIEKKVLYGYWSAFVPDTPELGSPQSVSLMTLTLKDPSPKTRACALQVLSAILEGSKQFLSVAEDTTDHRMAFTPFSVTIASSIRELHRCLLLALVAESSSQTITQIIKCLANLVSNAPYNRLKLSLLTKVWNHIKPYIRHKDVNVRVSSLTLLGAIVSTHAPLPEVQLLLQQPCSSGLSSSNSATPHLSTPDCWDRVPGGSSLEEVSVSSPKASAEPCWLIRLCISTVVLPKEDSCSGSDAGSAVGSTYEPCPMRLEALQVLAHLARGYFSMAQLYLMELGEVICKCMGEANPSIQLHSVKLLEELGTGLIQQYKPDSNMAPEQRVPIYMVVMFWTAMLNGPLPRALQSSEHPTLQASACDALSSILPEAFSSLPNDKQILCITMLLGLNDNKNHLVKAATSRALGVYVLFPCLRQDVIFVADTANAILMSLQDKSLNVRAKAAWSLGNLTDTLIVNMDTPDPSFQDEFSGLLLLKMLQSAIHASTDKDKVKSNAVRALGNLLHFLQPTHIERPRFAEIIEESIQALISTVVNEAAMKVRWNACYAIGNVFKNPALPLGSAPWTSQAYKALTSVVMSCKNFKVRIRSAAALSIPGKRAQYGSLEQFAQIWNALVTALQKSEDTTDFLEFKYCASLRTHICQALLHLLSLASASDFPCIQDSLERNGDMIQFYILQFLKSGVEGDDPGAVHTPQERDQMVRVALKHIHSVQALPGDTAKRVIVIFLEDTLAIHCDSSGGQVALLGSSDQ", "length": 1178, "header": "tr|A0A8C2L8E4-1|A0A8C2L8E4_CRIGR Isoform 1 of HEAT repeat-containing protein 6 OS=Cricetulus griseus OX=10029 GN=Heatr6 PE=4 SV=1 CANONICAL=A0A8C2L8E4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2L8E4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L8E4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2L8E4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L8E4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773538", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773538", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1P8B4P1-1", "protein_name": "ARM repeat superfamily protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MFTAAASSSVGRWRTAFLSLRDEISTTPPPPVPLLLEDLLFSQSHSLISAVSHLPLHELTSDCLFLLDLVSKADGPDWIPVSRHTCQLIHDVCARLLFQLNSSSWPLLLHSFASVLEFLLRQPMPSSPYSAAYFSRIEPVIQCFETLRRLAPMHPENIHLVKFLVRVVPLLHQDLVLSYGFSNQDPSPTLLVEKKLPQQNRLWDSMALAFDMFGRAFSLSESLFPTDVSQCTLEVLRKVMDVLASKGQLVEDRFMWSFYSCLLGCVHEVLTNIKCPVSDHVLSFIASLRMFFCFGLTGPPQLSVSDVVHNDKHLNVKLSPLISGVSKNAKNTPYRPPHLRKRDDLNTRQPVSSSWRRLSAHDSGSSDVISSDSDFSDSDGSVPDSYFAQSSKVRIAAIVCIQDLCQADSKSFTTQWVTLFPTSDVLKPRKFEATLMTCLLFDPHLKVRIASASALATMMDGPSSIFLQVAEYKESTKYGSFMPLSNSLGLILMQLHTGILHLIHSDNHGRLLIQLFKILLLLISSTPYSRMPGELLPKVIMSLHARINEGFPFKNDKTGLLVAAIGCLSAAFSTFPPQMKVHNMLLDETSAGFNGCEWNSGVLSTLFRFAEQFSDASTCIEALQVLRAVALNYPTLVPAYWERVSILVYKLLQSAVVEDSPTTWKSSVRESVGYNGDKVLTAAIKVLDGCLRAISGFKGTEDLQYDRLMDTPFTSDCIRSIRISSAPSYGFDNTQEPIFQAGCDQWSEAIRKHIVLVLHHGSAVVRSTTVTCFAGITSSIFSAFNKQEKDFITSSIITAALHDKTPSVRSAACRAIGVISCFPETSLSAEIYEKFILAVEANTRDSLTSVRITASWALANLCDALRYRVDDRSFEGLKTTSQVVDALIECALRLTEDGDKVKSNAVRALGSISKYVKLRCMTSIKSVDQDVLPFPHQQSSNSHHLSCAVDTRWLERTVQAFLSCVTTGNVKVQWNVCHALSNLFSNETVKLQDMDWAPSVFSILLLLLRDASNFKIRIQAASALAVPATPLAYGRSFPDVVKGVEHTLQSLHSDRETTPANFKYKRSLENQLTSTMLHLLSLVSSCHFEALSEFLIRKASFLEEWLRGLCVTLKEEDNVSGSSGTSTSGGKQKKELISRAIRSLARSLRAGHSSEMAQKLQELDSNVN", "length": 1168 }, "evidence": [ { "id": "A0A8C2L8E4", "url": "https://omabrowser.org/oma/group/A0A8C2L8E4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A1EC95-1", "protein_name": "HEAT repeat-containing protein 6", "gene_name": "Heatr6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSALPGSKLSERVRTVGWQISRPYFCHFFPIRITAPPATCSANKGFPELEHARPCPKRCPGSISQAIHVGKMAAVQVAASLPCEQPREAPRELSLEQNNGFRRLSARLRALQPDDSTVSRMEIHLLFDQLISENYCEGGGVAPEDVSALLVRACQLVPLNQNHLVSKVSQLIHRLLNRLQVIVDEQNLDFLLTYTISAIQQCSPWTHMEILQALAALVYCNGSKCQKHLPDLLGKSGLLMKLSDVTHSDPEVRRAAVHCMANLCLSVPGQPYLEESYQLVCFQAFLTILQSPKSSDMDDITFCMLLQNALKGIQSLLNGGKMRLTQTEHLGALLAVLKKAMFHGLPGLNIEMPAVLYPTPLPQYDGRSPVKPQQPESSAARPSANKKKKYKVKPKKTQQGEKAEEEEPYGEVDAAPGLSMDQANTCVESAWCSSPWGSQGLPVDGGRATGREQVSSPFTISSWKRVSSSESDYSDAEGGMQGKMRSYQAKVRQGALACFLSTIKSIEKKVLYGYWSAFVPDTPELGSPQSVSLMTLTLKDPSPKTRACALQVLSAILEGSKQFLSVAEDTSDHKRAFTPFSVTIASSIRELHRCLLLALVAESSSQTLTQIIKCLANLVSNAPYNRLKLSLLTKVWNHIKPYIRHKDVNVRVSSLTLLGAVVSTHAPLPEVQLLLQQPCSSGRSSSSATPHLSTPDGWKALPAGPSLEEASLSSPKGTAEPCWLIRLCISTVVLPKEDSCSGSDAGSALGSTYEPSPMRLEALQVLAHLARGYFSMAQLYLMELGEVICKCMCEANPSIQLHGVKLLEELGTGLIQQYKPDSSTAPEQRVPVHMVAMFWTAMLNGPLPRALQSTEHPTLQASACDALSSILPEAFSSLPNDKQILCITMLLGLNDSKNHLVKAATSRALGVYVLFPCLRQDVIFVADTANAILMSLQDKSLNVRAKAAWSLGNLTDTLIVNMDTPDPSFQDEFSGLLLLKMLQSAIQASTDKDKVKSNAVRALGNLLHFLQPSHIERPRFAEIIEESIQALISTVVNEAAMKVRWNACYAMGNVFKNPALPLGTAPWTSQAYKALTSVVMSCKNFKVRIRSAAALSVPGRRAQYGSLEQFSQIWSALVTALQRSEDTTDFLEFKYCASLRTHVCQALLHLLGLASASDLPCIQETLTVNGDMIRSYILQFLKSGAGGDDPGAVHSPQERNQMVRVALRHIHSVQALAGDTAKGAIVGFLEDILTVHCDSSGERAVLRGSLDQ", "length": 1252 }, "evidence": [ { "id": "A0A8C2L8E4", "url": "https://omabrowser.org/oma/group/A0A8C2L8E4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6AI08-1", "protein_name": "HEAT repeat-containing protein 6", "gene_name": "HEATR6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAVQVVGSWPSVQPREAPREAIPERGNGFRLLSARLCALRPDDSSSARTEIHLLFDQLISENYSEGSGVAPEDVSALLVQACRLVPLNQNHLVSKVSQLIHHLLNRLQVIVDEQHLDFLLAYTISAIHQCSSWTHREILQALAALVYCNGSKCQKYLPELLGNTGLLMKLSDLAQSDPEVRRAAVHCMANLCLSVPGQPYLEEPYQNVCFQAFLTILQSPKSSDMDDITFCMLLQNALKGIQSLLNGGRMKLTQTDELGALLAVLKKFMFHGLPGLNIEMPTVLYPTPLPQYDGRTPIKPQQSESSASRPTLNKKKKSKVKPKKIQQGEEEEKESSGEIEAAPVTGTGRVNLHEGNTWCPSSLGVQSLPLDGSGAAEKDGVSSSFSSSSWKRVSSSESDFSDAEGGMQSKMRSYQAKVRQGALVCFLSTIKSIEKKVLYGYWSAFIPDTPELGSPQSVSLMTLTLKDPSPKTRACALQVLSAILEGSKQFLSVAEDTSDHRRAFTPFSVMIACSIRELHRCLLLALVAESSSQTVTQIIKCLANLVSNAPYDRLKLSLLTKVWNQIKPYIRHKDVNVRVSSLTLLGAIVSTHAPLPEVQLLLQQPCSSGLGNSNSATPHLSPPDWWKKAPAGPSLEETSVSSPKGSSEPCWLIRLCISIVVLPKEDSCSGSDAGSAAGSTYEPSPMRLEALQVLTLLARGYFSMTQAYLMELGEVICKCMGEADPSIQLHGAKLLEELGTGLIQQYKPDSTAAPDQRAPVFLVVMFWTMMLNGPLPRALQNSEHPTLQASACDALSSILPEAFSNLPNDRQMLCITVLLGLNDSKNRLVKAATSRALGVYVLFPCLRQDVIFVADAANAILMSLEDKSLNVRAKAAWSLGNLTDTLIVNMETPDPSFQEEFSGLLLLKMLRSAIEASKDKDKVKSNAVRALGNLLHFLQPSHIEKPTFAEIIEESIQALISTVLTEAAMKVRWNACYAMGNVFKNPALPLGTAPWTSQAYNALTSVVTSCKNFKVRIRSAAALSVPGKREQYGSVDQYARIWNALVTALQKSEDTIDFLEFKYCVSLRTQICQALIHLLSLASASDLPCMKETLELSGNMVQSYILQFLKSGAEGDDTGAPHSPQERDQMVRMALKHMGSIQAPTGDTARRAIMGFLEEILAVCFDSSGSQGALPGLTNQ", "length": 1181 }, "evidence": [ { "id": "A0A8C2L8E4", "url": "https://omabrowser.org/oma/group/A0A8C2L8E4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P1G0-1", "protein_name": "HEAT repeat-containing protein 6", "gene_name": "Heatr6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAVQVAASLPCGQPREAPRELSPEQDDGFRRLSARLRALQPDDSTVSRMEIHLLFDQLISENYSEGGGVAPEDVSALLVRACQLVPLNQNHLVSKVCQLIHRLLNRLQVVVDEPNLDFLLTYTISALQQCSSWTHMEILQALAALVYCNGSKCQKHLPDLLGKSGLLMKLSDLSHSDPEVRRAAVHCMANLCLSVPGQPYLEEPYQHVCFQAFLTILQSPKSSDMDDITFCMLLQNALKGIQSLLNGGKMRLTQTEHLGALLAVLKKAMFHGLPGLNIEMPAVLYPTPLPQYDGRSPVKPQQPESTTARSSANKKKKHKVKTKKTQQGEKAEEEEEEPCGEVEAAPGLSMDQANVSGESAWCSSPWGSQGLPVDGGRAAGREQASLPFASSSWKRVSSSESDYSDAEGGMQGKMRSYQAKVRQGALACFLSTIKSIEKKVLYGYWSAFVPDTPELGSPQSVSLMTLTLKDPSPKTRACALQVLSAILEGSKQFLSVAEDTSDHKRAFTPFSVTIASSIRELHRCLLLALVAESSSQTLTQIIKCLANLVSNAPYNRLKLSLLTKVWNHIKPYIRHKDVNVRVSSLTLLGAIVSTHAPLPEVQLLLQQPCSSGLSSSSSATPHLSTPDGWKTFPAGSSLEEASLSSPKGSSEPCWLIRLCISTVVLPKEDSCSGSDAGSALGSTYEPSPMRLEALQVLAHLARGYFSTAQLYLMELGEVICKCMCEANPSIQLHGVKLLEELGAGLIQQYKPDSNIAPEQRVPVHLVVVFWTAMLSGPLPRALQSAEHPTLQASACDALSSILPEAFSSLPNDKQILCITVLLGLNDSKNHLVKAATSRALGVYVLFPCLRQDVIFVADTANAILMSLQDKSLNVRAKAAWSLGNLTDTLIVNMDTPDPSFQDEFSGLLLLKMLQCAIQASTDKDKVKSNAVRALGNLLHFLQPSHVERPRFAEIIEESIQALISTVVNEAAMKVRWNACYAMGNVFKNPALPLGTAPWTSQAYKALTSVVMSCKNFKVRIRSAAALSVPSKRGQYGSLEQFIQIWSALVTALQKSEDTTDFLEFKYCASLRTHICQALLHLLSLASASDLPGIQETLKLHGDMIRSYILQFLKSGAEGDDPGAVHTPQERVQMVRVALKHIHRVQTLAGDTARGAIMGFLEDILTVHCDSSGEQVMLRGPSDQ", "length": 1184 }, "evidence": [ { "id": "A0A8C2L8E4", "url": "https://omabrowser.org/oma/group/A0A8C2L8E4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 149, "end_pos": 151, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" }, { "start_pos": 879, "end_pos": 881, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2L8E4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L8E4" }, { "id": "PF13251", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13251" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF4042", "eco_id": "ECO_0000259", "start_pos": 415, "end_pos": 596, "start_aa": "Lys", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 149, "end_pos": 151 }, { "start_pos": 62, "end_pos": 64 }, { "start_pos": 879, "end_pos": 881 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2L9K0-1", "uniprot_ac": "A0A8C2L9K0", "uniprot_id": "A0A8C2L9K0_CRIGR", "mass": { "chemical_mass": 28953.0, "monoisotopic_mass": 28953.0 }, "refseq": { "ac": "XP_016829646", "name": "TM2 domain-containing protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016829646" }, "gene_names": [ { "name": "Tm2d3", "type": "recommended", "evidence": [ { "id": "A0A8C2L9K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L9K0" } ] }, { "name": "Tm2d3", "type": "synonym", "evidence": [ { "id": "XP_016829646", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016829646" } ] } ], "protein_names": [ { "name": "TM2 domain-containing protein 3", "type": "recommended", "evidence": [ { "id": "A0A8C2L9K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L9K0/entry#names_and_taxonomy" } ] }, { "name": "TM2 domain-containing protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_016829646", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016829646" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 118 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613734.1) and transcript sequence (IACG01088295.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_016829646.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016829646", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016829646" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2L9K0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L9K0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tm2d3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L9K0", "locus": {} } ], "crossref": [ { "id": "100771956", "url": "https://www.ncbi.nlm.nih.gov/gene/100771956", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007829", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007829", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050932", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050932", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771956", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771956", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2L9K0", "url": "https://www.orthodb.org/?gene=A0A8C2L9K0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21016", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21016", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21016:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21016:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05154", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05154", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016829646", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016829646", 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"id": "A0A9J7GWL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GWL4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAAAEPLRSVRRLSRVLLFLSQCYILSGDGSLNLEHSQPLAQSIKDPGPTRTFTIVPRAAENKLLSHLTESTEIPPYMMKCPSNGLCSRLPADCIECATNFSCTYGKPVTFDCTVKPSVTCVDQDLNPQRNFIINMTCRFCWQLPETDYECTNSTSCMTVACPRQRYLANCTVRDHIHCLGNRTFPKLLYCNWTGGYKWSTALALSITLGGFGADRFYLGQWREGLGKLFSFGGLGIWTLIDVLLIGVGYVGPADGSLYI", "length": 261, "header": "tr|A0A8C2L9K0-1|A0A8C2L9K0_CRIGR Isoform 1 of TM2 domain-containing protein 3 OS=Cricetulus griseus OX=10029 GN=Tm2d3 PE=3 SV=1 CANONICAL=A0A8C2L9K0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2L9K0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L9K0/entry#A0A8C2L9K0-1", "sequence": { "sequence": "MEAAAEPLRSVRRLSRVLLFLSQCYILSGDGSLNLEHSQPLAQSIKDPGPTRTFTIVPRAAENKLLSHLTESTEIPPYMMKCPSNGLCSRLPADCIECATNFSCTYGKPVTFDCTVKPSVTCVDQDLNPQRNFIINMTCRFCWQLPETDYECTNSTSCMTVACPRQRYLANCTVRDHIHCLGNRTFPKLLYCNWTGGYKWSTALALSITLGGFGADRFYLGQWREGLGKLFSFGGLGIWTLIDVLLIGVGYVGPADGSLYI", "length": 261, "header": "tr|A0A8C2L9K0-1|A0A8C2L9K0_CRIGR Isoform 1 of TM2 domain-containing protein 3 OS=Cricetulus griseus OX=10029 GN=Tm2d3 PE=3 SV=1 CANONICAL=A0A8C2L9K0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FNP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L9K0/entry#A0A9J7FNP4-1", "sequence": { "sequence": "MEAAAEPLRSVRRLSRVLLFLSQCYILSGDENKLLSHLTESTEIPPYMMKCPSNGLCSRLPADCIECATNFSCTYGKPVTFDCTVKPSVTCVDQDLNPQRNFIINMTCRFCWQLPETDYECTNSTSCMTVACPRQRYLANCTVRDHIHCLGNRTFPKLLYCNWTGGYKWSTALALSITLGGFGADRFYLGQWREGLGKLFSFGGLGIWTLIDVLLIGVGYVGPADGSLYI", "length": 230, "header": "tr|A0A9J7FNP4-1|A0A9J7FNP4_CRIGR Computationally mapped isoform of TM2 domain-containing protein 3 OS=Cricetulus griseus OX=10029 GN=Tm2d3 PE=3 SV=1 CANONICAL=A0A8C2L9K0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FSE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L9K0/entry#A0A9J7FSE9-1", "sequence": { "sequence": "MEAAAEPLRSVRRLSRVLLFLSQCYILSGDGSLNLEHSQPLAQSIKDPGPTRTFTIVPRAAENKLLSHLTESTEIPPYMMKCPSNGLCSRLPADCIECATNFSCTYGKPVTFDCTVKPSVTCVDQDLNPQRNFIINMTCRFCWQLPETDYECTNSTSCMTVACPRQRYLANCTVRDHIHCLASPSGDLEQIASTWASGVKASASSSALVAWEYGH", "length": 215, "header": "tr|A0A9J7FSE9-1|A0A9J7FSE9_CRIGR Computationally mapped isoform of TM2 domain-containing protein 3 isoform X6 OS=Cricetulus griseus OX=10029 GN=Tm2d3 PE=4 SV=1 CANONICAL=A0A8C2L9K0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GWL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L9K0/entry#A0A9J7GWL4-1", "sequence": { "sequence": "MGNIITAVSQWKERDPSSKSVRAIQVPVTSGRGPPCWKPAVPTTEPEPSSSAPAGRARTRPLRRAPQPRLLARKCARAPARWRLRRSRCGLSAACPACCSSSPSATFCRAMDQDLNPQRNFIINMTCRFCWQLPETDYECTNSTSCMTVACPRQRYLANCTVRDHIHCLGNRTFPKLLYCNWTGGYKWSTALALSITLGGFGADRFYLGQWREGLGKLFSFGGLGIWTLIDVLLIGVGYVGPADGSLYI", "length": 249, "header": "tr|A0A9J7GWL4-1|A0A9J7GWL4_CRIGR Computationally mapped isoform of TM2 domain-containing protein 3 OS=Cricetulus griseus OX=10029 GN=Tm2d3 PE=3 SV=1 CANONICAL=A0A8C2L9K0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 51, "start_aa": "Thr", "end_pos": 51, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr51", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613649.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003497481", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497481" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2L9T4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L9T4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tcp11l1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L9T4", "locus": {} } ], "crossref": [ { "id": "100771847", "url": "https://www.ncbi.nlm.nih.gov/gene/100771847", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008862", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008862", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771847", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771847", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CRDEDIN", "url": "https://omabrowser.org/oma/group/CRDEDIN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2L9T4", "url": "https://www.orthodb.org/?gene=A0A8C2L9T4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12832", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12832", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12832:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12832:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05794", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05794", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003497481", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003497481", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2L9T4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L9T4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2L9T4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L9T4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSENLDKSHINEAGESKPSDSEQGLEGALECSDEALQKKIKSDSPSPQRVGRPHSSPARLVTVEELLETAKGVTNMALAHEIVVNGDFRIKAVELAEGSLEKRVKEIVHKAFWDCLSVQLSEDPPTYDHAIKLVGEIKETLLSFLLPGHTRLRDQITEVLDLELIKQEAENGALDISKLAEFIIGMMGTLCAPARDEEVKKLKDIKEIVPLFRAIFSVLDLMKVDMANFAISSIRPHLMQQSVEYERKKFQEVLEKQPNSLDFVTQWLEEASNDLLTQKYKHTLPAGGGAAGSGDAPVLTPVSVQNYAYLRLLKWDHFRRPFPETVLMDQSRFQELQLQLEQLAILGAVLLVTLSSATPGISGRADFAEKLKMTVKILLMDMHLPSFHLEDALTSIGEKVCLEVSSCLSLCGSSPFSINKETVLKGQIQALASPDDPIRRIVESRIFTFLETYLASGHQKLLATVPGGLGPIQKELEEVAVKFVRLVNYNKMVFCPYYDAILSKLLLRS", "length": 509, "header": "tr|A0A8C2L9T4-1|A0A8C2L9T4_CRIGR Isoform 1 of T-complex protein 11-like protein 1 OS=Cricetulus griseus OX=10029 GN=Tcp11l1 PE=3 SV=1 CANONICAL=A0A8C2L9T4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2L9T4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L9T4/entry#A0A8C2L9T4-1", "sequence": { "sequence": "MSENLDKSHINEAGESKPSDSEQGLEGALECSDEALQKKIKSDSPSPQRVGRPHSSPARLVTVEELLETAKGVTNMALAHEIVVNGDFRIKAVELAEGSLEKRVKEIVHKAFWDCLSVQLSEDPPTYDHAIKLVGEIKETLLSFLLPGHTRLRDQITEVLDLELIKQEAENGALDISKLAEFIIGMMGTLCAPARDEEVKKLKDIKEIVPLFRAIFSVLDLMKVDMANFAISSIRPHLMQQSVEYERKKFQEVLEKQPNSLDFVTQWLEEASNDLLTQKYKHTLPAGGGAAGSGDAPVLTPVSVQNYAYLRLLKWDHFRRPFPETVLMDQSRFQELQLQLEQLAILGAVLLVTLSSATPGISGRADFAEKLKMTVKILLMDMHLPSFHLEDALTSIGEKVCLEVSSCLSLCGSSPFSINKETVLKGQIQALASPDDPIRRIVESRIFTFLETYLASGHQKLLATVPGGLGPIQKELEEVAVKFVRLVNYNKMVFCPYYDAILSKLLLRS", "length": 509, "header": "tr|A0A8C2L9T4-1|A0A8C2L9T4_CRIGR Isoform 1 of T-complex protein 11-like protein 1 OS=Cricetulus griseus OX=10029 GN=Tcp11l1 PE=3 SV=1 CANONICAL=A0A8C2L9T4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 358, "start_aa": "Thr", "end_pos": 358, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr358", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2L9T4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L9T4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2L9T4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L9T4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771847", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771847", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K6F1-1", "protein_name": "T-complex 11 like 1", "gene_name": "Tcp11l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSENLDKSHVNEAGESKSAASEEGQKGALECSDEALQEKVKSDSPSPLRVGRPHSSPPRLVTVEELLETAKGVTNMALAHEIVVNGDFRINAVELAEGSLEKRVKEIVHKAFWDCLSVQLSEDPPTYDHAIKLVGEIKETLLSFLLPGHTRLRNQITETLDLELIKQEAENGALDISKLAEFIVGMMGILCAPARDEEVKKLKDVKEIVPLFRAIFSVLDLMKVDMANFAISSIRPHLMQQSVEYERKKFQEVLEKQPNSLDFVTQWLEEASNDLLTQKCKHALPAGGGAAGSGDAPLLTAASVQNYAYLKLLKWDHFRRPFPETVLMDQPRFQELQLQLEQLALLGAVLLVTFSTSAPAVSGHAGFAEKLKTVVKILLADVHLPSFQLEDALTSIGEKVCLEVSSCLSMCGSSPFSVSKETVLKGQIQALASPDDPIRRIMESRILTFLETYLASGHQKLLPTVPGGLGPIQKELEEVAVKFVRLVNYNKMVFCPYYDEILSKLLLRS", "length": 509 }, "evidence": [ { "id": "A0A8C2L9T4", "url": "https://omabrowser.org/oma/group/A0A8C2L9T4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A3Q1LT06-1", "protein_name": "T-complex 11 like 1", "gene_name": "TCP11L1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSENLDKSNINEAGKSKSSDSEQGLEDAVEVSDEALQKKIKSGSPSTQRVQRPHSSPPRFVTVEELLETAKGVTNMALAHEIVINGDFQIKPVELPEDSLEKRVKDIVHKAFWDCLSVQLSEVPPTYDRAIKLVGEIKETLLSFLLPGHTRLRNQITEVLDLDLIKQEAENGALDISKLAEFIIGMMGTLCAPVRDEEVKKLKDIKEIVPLFRAIFSVLDLMKVDMANFAVSSIRPHLMQQSIEYERKQFQEFLEKQPNSLDFVTQWLQEATDDLMSQKYKNALPAAGGAAGSGDGPQLDPVAVQNYAYLKLLKWDHLHRPFPETVLMDHSRFQEFQLQLEQLTVLGAVLLVTFSMAAPGIASRADFAEKLKMIVKILLTDMHLPSFHLEDALTAVGEKVCLEVSSCLSLCGLSPLTTDKEAVLKGQIQAVASPDNPIRRIVDSRILTFLDAYLASSHQKPSPIAPGGLGPIQKELEEVAVKFVRLVNYNKMVFSPYYDAILSKTLARS", "length": 509 }, "evidence": [ { "id": "A0A8C2L9T4", "url": "https://omabrowser.org/oma/group/A0A8C2L9T4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "I3L8N0-1", "protein_name": "T-complex 11 like 1", "gene_name": "TCP11L1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSENLDKSNINEAGKSKSNDSEQGLEDAVEGSDEALQKKIKSGSPSTQRVQRPHSSPPRFVTVEELLETAKGVTNMALAHEIVVNGDFRIKPVELPEDSLEKRVKDIVHKAFWDCLSVQLSEDPPTYDRAIKLVGEIKETLLSFLLPGHTRLRNQITEVLDLDLIKQEAENGALDISKLAEFIIGMMGTLCAPVRDEEVKKLKDIKEIVPLFRAIFSVLDMMKVDMANFAVSSIRPHLMQQSVEYERKQFQELLEKQPNSLDFVTQWLEEAADDLMNQRYRNALPAGGGAAGSEASPRPDPAAVQNYAYLKLLKWDHLHRLFPETVLMDRSRFQELQLQLEQLTVLGAVLLVTFSMAAPGISSRADFAEKLKMIVKILLTDMHQPSFHLEDALTAVGEKVCLEVSSCLSQCGFSPLTPDKEAVLKGQIQAVASPDNPIRRIMDSRILTFLETHLASSHQKPLPTAPGGLGPVQKELEEVAVKFVRLVNYNKMVFSPYYDAILSKILATS", "length": 509 }, "evidence": [ { "id": "A0A8C2L9T4", "url": "https://omabrowser.org/oma/group/A0A8C2L9T4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8BTG3-1", "protein_name": "T-complex protein 11-like protein 1", "gene_name": "Tcp11l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSENLDKSHVDEAGEAEAAASEQGLEGALECSDETLQKKVKSDSPSSQRVGRPHSSPARLVTVEELLETAKGVTNMALAHEIVVTGDFRINAVELAEGSLEKRVKEIVHKAFWDCLSVQLSEEPPTYDHAIKLVGEIKETLLSFLLPGHTRLRNQITEVLDLELIKQEAENGALDISKLAEFIIGMMGILCAPARDEEVKKLKGIKEIVPLFRAIFSVLDLMKVDMANFAISSIRPHLMQQSVEYERRKFQEVLERQPNSLDFATQWLEEATNDLLSQKYKHALPAGGGAAGSGDAPLLTPVSVQNFAYLKLLKWDHFQRPFPETVLMDQSRFQELQLQLEQLAVLGAVLLVTFSTAAPGISGHADFAEKLKMMVKTLLTDMHLPSFHLEDALASIGEKVCLEVSSCLSLCGSSPFSVAKETVLKGQIQALASPEDPIRRIMESRIFTFLETYLASGHQKPLPTVPGGLGPIQKELEEVAVKFVRLVNYNKMVFCPYYDAILSKLLLRS", "length": 509 }, "evidence": [ { "id": "A0A8C2L9T4", "url": "https://omabrowser.org/oma/group/A0A8C2L9T4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NUJ3-1", "protein_name": "T-complex protein 11-like protein 1", "gene_name": "TCP11L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSENLDKSNVNEAGKSKSNDSEEGLEDAVEGADEALQKAIKSDSSSPQRVQRPHSSPPRFVTVEELLETARGVTNMALAHEIVVNGDFQIKPVELPENSLKKRVKEIVHKAFWDCLSVQLSEDPPAYDHAIKLVGEIKETLLSFLLPGHTRLRNQITEVLDLDLIKQEAENGALDISKLAEFIIGMMGTLCAPARDEEVKKLKDIKEIVPLFREIFSVLDLMKVDMANFAISSIRPHLMQQSVEYERKKFQEILERQPNSLDFVTQWLEEASEDLMTQKYKHALPVGGMAAGSGDMPRLSPVAVQNYAYLKLLKWDHLQRPFPETVLMDQSRFHELQLQLEQLTILGAVLLVTFSMAAPGISSQADFAEKLKMIVKILLTDMHLPSFHLKDVLTTIGEKVCLEVSSCLSLCGSSPFTTDKETVLKGQIQAVASPDDPIRRIMESRILTFLETYLASGHQKPLPTVPGGLSPVQRELEEVAIKFARLVNYNKMVFCPYYDAILSKILVRS", "length": 509 }, "evidence": [ { "id": "A0A8C2L9T4", "url": "https://omabrowser.org/oma/group/A0A8C2L9T4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W461-1", "protein_name": "T-complex protein 11-like protein 1", "gene_name": "Dmel\\CG16721", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDAQENRSEQSGQSGDHEEHEERRIRTDSESSVESMTRFVLPSLDGTPPKIVTLDEVSSMFKNLRNMELAHEIALNPDFKLQKYEPPSDSLEGAIKKMVHKAFWDLLRVQLDRQPPSYDQAIRLLAEIKECFPQLLSPNNERALAHINEVLDDSVIRQQAERGTLDFRAYANFVINILSRSCSPARDEAVAALRKIDDVVDTFRCILELMTLMKLDMANFMLRLARTEIAANSVQYEKEKFSKYLREFHGNVGFPATEDWLQRHRSGSSDDETIYNAYMQLIDYPADKEFPELLRIDKERFAGLSWRAQRLILCASLISVAQGMPIISQRRENRIKLAQQLDIIVQDIKNQDQVASTIESCYEQIRSFVNKALEQENLPALSDADQAALKNQVLKLANKTSPVPSLMAKRLDGYVRVTLRSNGSIPPPPSGFADYQEELVAFIASFRRLVSYNHAVFGEHFHQILNKTLPGEETEATTSTASGINPGQAQTAKP", "length": 494 }, "evidence": [ { "id": "A0A8C2L9T4", "url": "https://omabrowser.org/oma/group/A0A8C2L9T4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "microtubule", "id": "GO:0005874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005874", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2L9T4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L9T4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2L9T4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2L9T4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 358 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LA31-1", "uniprot_ac": "A0A8C2LA31", "uniprot_id": "A0A8C2LA31_CRIGR", "mass": { "chemical_mass": 34252.0, "monoisotopic_mass": 34252.0 }, "refseq": { "ac": "XP_027284008", "name": "keratin-like protein KRT222 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284008" }, "gene_names": [ { "name": "Krt222", "type": "recommended", "evidence": [ { "id": "A0A8C2LA31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA31" } ] }, { "name": "Krt222", "type": "synonym", "evidence": [ { "id": "XP_027284008", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284008" } ] } ], "protein_names": [ { "name": "Keratin-like protein KRT222 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A8C2LA31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA31/entry#names_and_taxonomy" } ] }, { "name": "keratin-like protein KRT222 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027284008", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284008" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027284008", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284008" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LA31", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA31" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Krt222", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA31", "locus": {} } ], "crossref": [ { "id": "100762604", "url": "https://www.ncbi.nlm.nih.gov/gene/100762604", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002957", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002957", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018039", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018039", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052857", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052857", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762604", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762604", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LA31", "url": "https://www.orthodb.org/?gene=A0A8C2LA31", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47082", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47082", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47082:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47082:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027284008", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284008", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LA31", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LA31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA31-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MELSQLLNEIRANYEQLLTRNQIETVLSTRMQLEEDITKKMDKDEEALKAAQAELREARRQCHHLQVEIESLHAVERGLENSLQASEQHYQMQLQDLESVIDRLEKELQEVRFGIERQLQEHEMLLNTKMRLEQEIATYRRLLEQEELRYYGCIQGEKKEEKPTRSKVGFLLPSAIINEISFSTKVSQKYENDNTETMTKQAVLNGNVKESAEAHGTIQTEKVDEVIKEWEGSFFKDNPRLRKKSVSLRFDLHLAATDEGCLQSRQDNLPDIEVRLIMRRSCSIPSIKPPPATN", "length": 294, "header": "tr|A0A8C2LA31-1|A0A8C2LA31_CRIGR Isoform 1 of Keratin-like protein KRT222 isoform X2 OS=Cricetulus griseus OX=10029 GN=Krt222 PE=3 SV=1 CANONICAL=A0A8C2LA31-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LA31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA31/entry#A0A8C2LA31-1", "sequence": { "sequence": "MELSQLLNEIRANYEQLLTRNQIETVLSTRMQLEEDITKKMDKDEEALKAAQAELREARRQCHHLQVEIESLHAVERGLENSLQASEQHYQMQLQDLESVIDRLEKELQEVRFGIERQLQEHEMLLNTKMRLEQEIATYRRLLEQEELRYYGCIQGEKKEEKPTRSKVGFLLPSAIINEISFSTKVSQKYENDNTETMTKQAVLNGNVKESAEAHGTIQTEKVDEVIKEWEGSFFKDNPRLRKKSVSLRFDLHLAATDEGCLQSRQDNLPDIEVRLIMRRSCSIPSIKPPPATN", "length": 294, "header": "tr|A0A8C2LA31-1|A0A8C2LA31_CRIGR Isoform 1 of Keratin-like protein KRT222 isoform X2 OS=Cricetulus griseus OX=10029 GN=Krt222 PE=3 SV=1 CANONICAL=A0A8C2LA31-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LA31", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA31" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LA31", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA31" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762604", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762604", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "intermediate filament", "id": "GO:0005882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005882", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LA31", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA31" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LA31", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA31" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LA31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LA31" }, { "id": "PS51842", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51842" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IF rod", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 150, "start_aa": "Met", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": 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This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035299903", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299903" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LAH7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAH7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Lrrc2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAH7", "locus": {} } ], "crossref": [ { "id": "100767975", "url": "https://www.ncbi.nlm.nih.gov/gene/100767975", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767975", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767975", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PIDNTQC", "url": "https://omabrowser.org/oma/group/PIDNTQC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LAH7", "url": "https://www.orthodb.org/?gene=A0A8C2LAH7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12799", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12799", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27680", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27680", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035299903", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299903", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LAH7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LAH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAH7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGHKVVVFDISVVRALWETRVKKHKAWQKKEAERLEKSALEKIKEEWDFVAECRRKGVPQAQYCKNGFVDTNSRILDKIERNSVARQSSWVKDRGKQSNPFVFELSGAQWKELPDSLKEQTHLKEWHIHSTLIQTIPAYIELFQAMRILDLPENQITCLPAEIGRLKNLKELNVSFNHLRSIPPELGDCENLERLDCSGNLDLMELPFELSNLKQVTFVDISANNFSSVPICVLRMCRLQWLDISSNNLSDLPQDIDRLEELQSFLLYKNKLTYLPQAMLNLKKLTLLVVSGDHLVELPTALCDASTPLKFVSLMDNPIDKAQCQDSDETIESEQDRQHFDKEFMKAYIEDLKEREAVPSYTTKVSFSLQL", "length": 371, "header": "tr|A0A8C2LAH7-1|A0A8C2LAH7_CRIGR Isoform 1 of Leucine-rich repeat-containing protein 2 OS=Cricetulus griseus OX=10029 GN=Lrrc2 PE=4 SV=1 CANONICAL=A0A8C2LAH7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LAH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAH7/entry#A0A8C2LAH7-1", "sequence": { "sequence": "MGHKVVVFDISVVRALWETRVKKHKAWQKKEAERLEKSALEKIKEEWDFVAECRRKGVPQAQYCKNGFVDTNSRILDKIERNSVARQSSWVKDRGKQSNPFVFELSGAQWKELPDSLKEQTHLKEWHIHSTLIQTIPAYIELFQAMRILDLPENQITCLPAEIGRLKNLKELNVSFNHLRSIPPELGDCENLERLDCSGNLDLMELPFELSNLKQVTFVDISANNFSSVPICVLRMCRLQWLDISSNNLSDLPQDIDRLEELQSFLLYKNKLTYLPQAMLNLKKLTLLVVSGDHLVELPTALCDASTPLKFVSLMDNPIDKAQCQDSDETIESEQDRQHFDKEFMKAYIEDLKEREAVPSYTTKVSFSLQL", "length": 371, "header": "tr|A0A8C2LAH7-1|A0A8C2LAH7_CRIGR Isoform 1 of Leucine-rich repeat-containing protein 2 OS=Cricetulus griseus OX=10029 GN=Lrrc2 PE=4 SV=1 CANONICAL=A0A8C2LAH7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027261620.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027261620", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261620" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LAJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAJ8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Lrrc36", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAJ8", "locus": {} } ], "crossref": [ { "id": "100761482", "url": "https://www.ncbi.nlm.nih.gov/gene/100761482", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761482", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761482", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LAJ8", "url": "https://www.orthodb.org/?gene=A0A8C2LAJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23311", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23311", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23311:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23311:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14580", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14580", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027261620", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027261620", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LAJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LAJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEQWDLDEEGLRRLGALTLEQPELVESLSLQGSYAGKIHSIGDAFRNFKNLRSLDLSRNLITSLKGIQYLCSLQDLNLYYNNIPSLVEVSRLQPLPFLKELDLRLNPVVRKDTDYRLFAVYTLQTLEKLDDRTVRDSERKAAKLHFSQLGNSENFLLEVEKSSREKTMKNCVTDESSASKVNPEVDNRTETDANKGLFIPFPNREIKDSLTNTSASQSNGTPAQKLDVFPLGTQMQEAARRETSDTHKGDGLEFRHYSPHQSTVRSPEKMSRDGYRVSFLDSKSSGSSPEKDLIPKPDTYPRTHDVSLGKHLDVGDSNQILPYQLPSDVSLDYYDNHYSQTLSLHGSLVKRPQKIKNYGEYSIKPSNDTKATSSHSCGDLLTSLSNPDSSTGRLLKLSSDLYATTHFNSDPALRTNVEQQLPSSLSDFAPAHGSFPSNRVLGNSLRTLLLPSGTPENREIPTKRSLSGGFKGKDNVLANLNLKCGFQEATGSEAQPLSSDLGSLHGLPGNHSPPISARTPHVATVLRQLLELVDKHWNGSGSLLLNKKFLGPARDLLLSLVVPAPPQQWCRSQHEDKAGHAFRWRENELKEAGQLVPNDVENLKQKLVKVLEENLILSEKIQQLEGGAATPVVSGHPSHTHDDLQRKNQQLTIQVACLNQELTQLKRLEETVALLHESQRSLVVTNEYLLQQLNKEQKGYSGKSLLPPEKNHPLGRSSPFGKSSLSSSSPMAHDTGQYLIQAVSEAAPEPSLWS", "length": 755, "header": "tr|A0A8C2LAJ8-1|A0A8C2LAJ8_CRIGR Isoform 1 of Leucine-rich repeat-containing protein 36 OS=Cricetulus griseus OX=10029 GN=Lrrc36 PE=4 SV=1 CANONICAL=A0A8C2LAJ8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LAJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAJ8/entry#A0A8C2LAJ8-1", "sequence": { "sequence": "MAEQWDLDEEGLRRLGALTLEQPELVESLSLQGSYAGKIHSIGDAFRNFKNLRSLDLSRNLITSLKGIQYLCSLQDLNLYYNNIPSLVEVSRLQPLPFLKELDLRLNPVVRKDTDYRLFAVYTLQTLEKLDDRTVRDSERKAAKLHFSQLGNSENFLLEVEKSSREKTMKNCVTDESSASKVNPEVDNRTETDANKGLFIPFPNREIKDSLTNTSASQSNGTPAQKLDVFPLGTQMQEAARRETSDTHKGDGLEFRHYSPHQSTVRSPEKMSRDGYRVSFLDSKSSGSSPEKDLIPKPDTYPRTHDVSLGKHLDVGDSNQILPYQLPSDVSLDYYDNHYSQTLSLHGSLVKRPQKIKNYGEYSIKPSNDTKATSSHSCGDLLTSLSNPDSSTGRLLKLSSDLYATTHFNSDPALRTNVEQQLPSSLSDFAPAHGSFPSNRVLGNSLRTLLLPSGTPENREIPTKRSLSGGFKGKDNVLANLNLKCGFQEATGSEAQPLSSDLGSLHGLPGNHSPPISARTPHVATVLRQLLELVDKHWNGSGSLLLNKKFLGPARDLLLSLVVPAPPQQWCRSQHEDKAGHAFRWRENELKEAGQLVPNDVENLKQKLVKVLEENLILSEKIQQLEGGAATPVVSGHPSHTHDDLQRKNQQLTIQVACLNQELTQLKRLEETVALLHESQRSLVVTNEYLLQQLNKEQKGYSGKSLLPPEKNHPLGRSSPFGKSSLSSSSPMAHDTGQYLIQAVSEAAPEPSLWS", "length": 755, "header": "tr|A0A8C2LAJ8-1|A0A8C2LAJ8_CRIGR Isoform 1 of Leucine-rich repeat-containing protein 36 OS=Cricetulus griseus OX=10029 GN=Lrrc36 PE=4 SV=1 CANONICAL=A0A8C2LAJ8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LAJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAJ8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LAJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAJ8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761482", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761482", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" }, { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 511, "end_pos": 513, "annotation": "n_glycosylation_sequon" }, { "start_pos": 539, "end_pos": 541, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 188, "end_pos": 190 }, { "start_pos": 213, "end_pos": 215 }, { "start_pos": 220, "end_pos": 222 }, { "start_pos": 368, "end_pos": 370 }, { "start_pos": 511, "end_pos": 513 }, { "start_pos": 539, "end_pos": 541 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LAR1-1", "uniprot_ac": "A0A8C2LAR1", "uniprot_id": "A0A8C2LAR1_CRIGR", "mass": { "chemical_mass": 36345.0, "monoisotopic_mass": 36345.0 }, "refseq": { "ac": "XP_035293066", "name": "olfactory receptor 52W1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293066" }, "gene_names": [ { "name": "LOC100752183", "type": "recommended", "evidence": [ { "id": "A0A8C2LAR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAR1" } ] }, { "name": "LOC100752183", "type": "synonym", "evidence": [ { "id": "XP_035293066", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293066" } ] } ], "protein_names": [ { "name": "Olfactory receptor 52W1", "type": "synonym", "evidence": [ { "id": "A0A8C2LAR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAR1/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 52W1", "type": "synonym", "evidence": [ { "id": "XP_035293066", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293066" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615765.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035293066", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293066" } ] }, { "annotation": "Odorant receptor.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LAR1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAR1#function" }, { "database": "UniProtKB", "id": "ARBA00002936", "url": "https://www.uniprot.org/uniprotkb/ARBA00002936#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LAR1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAR1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100752183", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAR1", "locus": {} } ], "crossref": [ { "id": "cd15917", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15917", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100752183", "url": "https://www.ncbi.nlm.nih.gov/gene/100752183", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752183", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752183", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DHAYCAH", "url": "https://omabrowser.org/oma/group/DHAYCAH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LAR1", "url": "https://www.orthodb.org/?gene=A0A8C2LAR1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26450:SF58", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26450:SF58", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035293066", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293066", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LAR1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LAR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAR1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKPKLHLYRMAHSLTPQSNSTIQCPPFFILTGIPGLRDGQAWLTLVFGPMYLLALLGNATLLTVIRIDSTLHQPMFLLLATLAATDLGLATSIAPGLLAVLWLGPRPVQYAVCLIQMFFVHALTAVESGVLLAMACDRAVAVGRPLHYPILVTKARVGYAVLALTLKAVAIVVPFPLLVARFEHFHAKIIHHAYCAHMAVVELVVGNTRVNNLYGLALSLAVSGVDILGIAGSYGLIAHAVLRLPTWEARAKAFGTCSSHICVILAFYVPGLFSYLTHRFGRHTVPKSVHILLSNIYLLLPPALNPLIYGVRTKQIRDRFLEMFKFRKNQF", "length": 331, "header": "tr|A0A8C2LAR1-1|A0A8C2LAR1_CRIGR Isoform 1 of Olfactory receptor 52W1 OS=Cricetulus griseus OX=10029 GN=LOC100752183 PE=3 SV=1 CANONICAL=A0A8C2LAR1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LAR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAR1/entry#A0A8C2LAR1-1", "sequence": { "sequence": "MKPKLHLYRMAHSLTPQSNSTIQCPPFFILTGIPGLRDGQAWLTLVFGPMYLLALLGNATLLTVIRIDSTLHQPMFLLLATLAATDLGLATSIAPGLLAVLWLGPRPVQYAVCLIQMFFVHALTAVESGVLLAMACDRAVAVGRPLHYPILVTKARVGYAVLALTLKAVAIVVPFPLLVARFEHFHAKIIHHAYCAHMAVVELVVGNTRVNNLYGLALSLAVSGVDILGIAGSYGLIAHAVLRLPTWEARAKAFGTCSSHICVILAFYVPGLFSYLTHRFGRHTVPKSVHILLSNIYLLLPPALNPLIYGVRTKQIRDRFLEMFKFRKNQF", "length": 331, "header": "tr|A0A8C2LAR1-1|A0A8C2LAR1_CRIGR Isoform 1 of Olfactory receptor 52W1 OS=Cricetulus griseus OX=10029 GN=LOC100752183 PE=3 SV=1 CANONICAL=A0A8C2LAR1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LAR1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAR1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LAR1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAR1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752183", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752183", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B563-1", "protein_name": "Olfactory receptor family 52 subfamily W member 1", "gene_name": "OR52W1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAEAPQPNSTFSRPAFFILTGLPGLGGAQAWLTLVFGPMYLLSLLGNGALLAVVHADTALHQPMFLLLAVLAATDLGLATSVAPGLLAVLWLGPRPVPYAACLVQMFFVHALTAVESGVLLAMACDRAVAVGRPLHYPVLVTKARVGYAALALALKAVAIVVPFPLLVARFGHFRARTIAHAYCAHMAVVELVVGDTRANNLYGLALSLAVSSVDILGITGSYGLIAHAVLRLPTREARAKAFGTCSSHVGVILAFYVPGLFSYLTHRFGRRTVPKPVHILLSNVYLLLPPALNPLIYGARTKQIRGRLLETFTPSRSRF", "length": 320 }, "evidence": [ { "id": "A0A8C2LAR1", "url": "https://omabrowser.org/oma/group/A0A8C2LAR1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M0R5W1-1", "protein_name": "Olfactory receptor family 52 subfamily W member 1", "gene_name": "Or52w1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "KRPKLHPYRMAEGSQSNSTFQCPAFFILTGIPGLGDGQAWLTLVFGLMYLLALLGNTTLLTVIRIDSTLHQPMFLLLATLAATDLGLATSIAPELLAVLWLGPQPVQYTACLIQMFFVHALTAMESGVLLAMACDRAVAVGRPLHYSILVTKARVGYAVLALTLKVVAVIVPFPLLVVRFKHFHTKIIYHAYCAHMAVVELVMGNTWVNNMYGLALSLAVSGVDILGIAGSYGLVAHAVLRVPTHEARVKAFGTCSSHICVILAFYVPGLFSFLTHRFGHHTVPKPVHILLSIIYLLLPPALNPLIYGVHTKQIRDRFLEMVKFRKKQF", "length": 329 }, "evidence": [ { "id": "A0A8C2LAR1", "url": "https://omabrowser.org/oma/group/A0A8C2LAR1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6IF63-1", "protein_name": "Olfactory receptor 52W1", "gene_name": "OR52W1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAETLQLNSTFLHPNFFILTGFPGLGSAQTWLTLVFGPIYLLALLGNGALPAVVWIDSTLHQPMFLLLAILAATDLGLATSIAPGLLAVLWLGPRSVPYAVCLVQMFFVHALTAMESGVLLAMACDRAAAIGRPLHYPVLVTKACVGYAALALALKAVAIVVPFPLLVAKFEHFQAKTIGHTYCAHMAVVELVVGNTQATNLYGLALSLAISGMDILGITGSYGLIAHAVLQLPTREAHAKAFGTCSSHICVILAFYIPGLFSYLTHRFGHHTVPKPVHILLSNIYLLLPPALNPLIYGARTKQIRDRLLETFTFRKSPL", "length": 320 }, "evidence": [ { "id": "A0A8C2LAR1", "url": "https://omabrowser.org/oma/group/A0A8C2LAR1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LAR1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAR1" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LAR1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAR1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LAR1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAR1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" }, { "start_pos": 58, "end_pos": 60, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LAR1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAR1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 57, "end_pos": 309, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 19, "end_pos": 21 }, { "start_pos": 58, "end_pos": 60 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LAU3-1", "uniprot_ac": "A0A8C2LAU3", "uniprot_id": "A0A8C2LAU3_CRIGR", "mass": { "chemical_mass": 114463.0, "monoisotopic_mass": 114463.0 }, "refseq": { "ac": "XP_007644703", "name": "BRD4-interacting chromatin-remodeling complex-associated protein-like isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644703" }, "gene_names": [ { "name": "Bicral", "type": "recommended", "evidence": [ { "id": "A0A8C2LAU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAU3" } ] }, { "name": "Bicral", "type": "synonym", "evidence": [ { "id": "XP_007644703", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644703" } ] } ], "protein_names": [ { "name": "BRD4-interacting chromatin-remodeling complex-associated protein-like isoform X2", "type": "synonym", "evidence": [ { "id": "XP_007644703", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644703" }, { "id": "A0A8C2LAU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAU3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614206.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007644703", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644703" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LAU3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAU3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Bicral", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAU3", "locus": {} } ], "crossref": [ { "id": "100768726", "url": "https://www.ncbi.nlm.nih.gov/gene/100768726", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR015671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052438", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052438", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DQFHPVP", "url": "https://omabrowser.org/oma/group/DQFHPVP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LAU3", "url": "https://www.orthodb.org/?gene=A0A8C2LAU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15572", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15572", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15572:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15572:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15249", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15249", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007644703", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644703", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LAU3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LAU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAU3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDDDDDSCLLDLIGDPQALNYFLHGPSNKSSSDDLTNAGYSAANSNSIFANSTNADPKSSLKGVSNQLGEGPSDGLPLSSSLQFLEDELESSPLPDLGEDQPFDILQKSLQEANITEQTLAEEAYLDASIGSSQQFAQAQLHPSSSASFTQASNVSNYSGQTLQPIGVTHVPVGASFASNTVGVQHGFMQHVGISVPSQHLPNSSQISGSGQIQLIGSFGNQPSMMTINNLDGSQIILKGSGQQTPTNVSGGLLVHRQTPNGNSLFGNSTSSPVAQPVTVPFNSTNFQASLPVHNIIIQRGLAPNSNKVPINIQPKPIQMGQQSAYNVNSLGIQQHHVQQGISFASASSPQGSVVGPHMSVNIVNQQNTRKPVTSQAVSSAGGSIVIHSPMGQPHTPQSQFLIPTSLSVSSNSVHHVQTINGQLLQTQPSQLISGQVASEHVMLNRNSSNMLRTNQPYSGQMLNNQNAAVQLVSGQTFATSGSPVIVNHASPQMVGGQMPLQRASPTVLHLSPGQSSASQGRPGFTAMPSVTSMSGPARFPTVSSASTAHTSLGSTVQSGASGSNFTGDQLTQPNRTPVPVSVSHRLPVSSSKPTSTFSNTPGTQQQFFCQAQKKCLTQPSPLPTAKTTDGLRQSQIPGLLSTALPGQDSGSKVMPASLGTAQPQQENTVGSSPSQTTVQVDSHSGQKRPATKQLTKGAFILQQLQRDQAHAVTPDKSQFRSLSDTVQRLLSYHVCQGSTPTEEDLRKVDNEFEEVATQLLKRTQAMLNKYRFLLLEDAMRINPSAEMVMIDRMFNQEERASLSRDKRLALVDPEGFQADFCCSFKVDEAAPEAPLDRSDQHRSKTSSLHQAPRSQSRDRPKAGMAEATNHDQFHLVPNHIVVSGEGSVSKKSEGHGRTLKYDKGGLGQYRGAPEDKGSRRDPANASGCSPGPEGHRKTMPRPDHGPESKLPGILASAHLEMPCLDSFQDRALRNSPKNEVLHTDIMKGSGEPQPDLQLTKSLEKTFKNILELKKAGRPQSDPAASGAMDLDFPSFSPMASQENCLEKFIPDHSEGVVETDSILEAAVNSILEC", "length": 1074, "header": "tr|A0A8C2LAU3-1|A0A8C2LAU3_CRIGR Isoform 1 of BRD4-interacting chromatin-remodeling complex-associated protein-like isoform X2 OS=Cricetulus griseus OX=10029 GN=Bicral PE=4 SV=1 CANONICAL=A0A8C2LAU3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LAU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAU3/entry#A0A8C2LAU3-1", "sequence": { "sequence": "MDDDDDSCLLDLIGDPQALNYFLHGPSNKSSSDDLTNAGYSAANSNSIFANSTNADPKSSLKGVSNQLGEGPSDGLPLSSSLQFLEDELESSPLPDLGEDQPFDILQKSLQEANITEQTLAEEAYLDASIGSSQQFAQAQLHPSSSASFTQASNVSNYSGQTLQPIGVTHVPVGASFASNTVGVQHGFMQHVGISVPSQHLPNSSQISGSGQIQLIGSFGNQPSMMTINNLDGSQIILKGSGQQTPTNVSGGLLVHRQTPNGNSLFGNSTSSPVAQPVTVPFNSTNFQASLPVHNIIIQRGLAPNSNKVPINIQPKPIQMGQQSAYNVNSLGIQQHHVQQGISFASASSPQGSVVGPHMSVNIVNQQNTRKPVTSQAVSSAGGSIVIHSPMGQPHTPQSQFLIPTSLSVSSNSVHHVQTINGQLLQTQPSQLISGQVASEHVMLNRNSSNMLRTNQPYSGQMLNNQNAAVQLVSGQTFATSGSPVIVNHASPQMVGGQMPLQRASPTVLHLSPGQSSASQGRPGFTAMPSVTSMSGPARFPTVSSASTAHTSLGSTVQSGASGSNFTGDQLTQPNRTPVPVSVSHRLPVSSSKPTSTFSNTPGTQQQFFCQAQKKCLTQPSPLPTAKTTDGLRQSQIPGLLSTALPGQDSGSKVMPASLGTAQPQQENTVGSSPSQTTVQVDSHSGQKRPATKQLTKGAFILQQLQRDQAHAVTPDKSQFRSLSDTVQRLLSYHVCQGSTPTEEDLRKVDNEFEEVATQLLKRTQAMLNKYRFLLLEDAMRINPSAEMVMIDRMFNQEERASLSRDKRLALVDPEGFQADFCCSFKVDEAAPEAPLDRSDQHRSKTSSLHQAPRSQSRDRPKAGMAEATNHDQFHLVPNHIVVSGEGSVSKKSEGHGRTLKYDKGGLGQYRGAPEDKGSRRDPANASGCSPGPEGHRKTMPRPDHGPESKLPGILASAHLEMPCLDSFQDRALRNSPKNEVLHTDIMKGSGEPQPDLQLTKSLEKTFKNILELKKAGRPQSDPAASGAMDLDFPSFSPMASQENCLEKFIPDHSEGVVETDSILEAAVNSILEC", "length": 1074, "header": "tr|A0A8C2LAU3-1|A0A8C2LAU3_CRIGR Isoform 1 of BRD4-interacting chromatin-remodeling complex-associated protein-like isoform X2 OS=Cricetulus griseus OX=10029 GN=Bicral PE=4 SV=1 CANONICAL=A0A8C2LAU3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LAU3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAU3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LAU3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAU3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8D1EG31-1", "protein_name": "BICRA like chromatin remodeling complex associated protein", "gene_name": "BICRAL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDDDDDSCLLDLIGDPQALNYFLHGPSNKSSNEDLTNAGYSAANSNSIFANSSNADPKSSLKAVSSQLGEGPSDGLPLSSSLQFLEDELESSPLPDLSEDQPFDILQKSLQEANITEQTLAEEAYLDASISSSQQFAQAPLHPSSSASFTQASNVSNYSGQTLQPIGVTHVPVGTSFASNTVGVHHGFMHHVGISVPSQHLSNSSQISGSGQIQLIGSFGNQPSMMTINNLDGSQIILKGSGQPAPSNVSGGGLLVHRQTPNGNSLFGNSSSSPVAQPVTVPFNSTNFQTSLPVHNIIIQRGLAPNSNKVPVNIQPKPVPMGQQNTYSVNNLGIQQHHVQQGISFASASSPQGSVVGPHMSVNIVNQQNPRKPVTSQAVSSAGGSIVIHSPMGQPHTPQSQFLIPTSLSVSSSSVHHVQTINGQLLQTQPPQLISGPVASEHVMLNRTSSNMLRTNQPYSGQMLNNQNTAVQLVSGQTFAASGSPVIVNHASSQIVSGQMPLQQASPTVLHLSPGQSSVSQGRPGFTTMPSVTSMSGPSRFPAVSSSSTAHPSLGSAVQSGASGSNFTGDQLAQPNRTPVPVSVSHRLPVPSSKSTSTFSNAPGAGTQQPFFCQAQKKSLNQTSPISASKTAEGLRQAPIPGLLSTALPGQDSGSKVIPASLGTTQPQQEKVVGSSPGQPAVQVDGHSGGQKRPAAKQLTKGAFILQQLQRDQAHAVTPDKSQFRSLSDAVQRLLSYHVCQGSMPTEEDLRKVDNEFETVATQLLKRTQAMLNKYRCLLLEDAMRINPSAEMVMIDRMFNQEERAALSRDKRLALVDPEGFQADFCCSFKPSKAAPETQFGRSDQPGSKAASSVHLPAKAQSRDRAKPGMAEPTNHDQFHLVPNHVVVSAEGSISKKTECLSRALKFDKMGSVQYQSASDDKGSRRDSLKGSECSPGPEGHRKNSSRPDHGPESKPSSILADSHLELTCNSSFQDKSLRNSPKNEVLHTDIMRGSGEPQPDLQLTKSLETTFKNILELKKAGRQPQSDPTVSGSVELDFPSFSPMASQENCLEKFIPDHSEGVVETDSILEAAVNSILEC", "length": 1080 }, "evidence": [ { "id": "A0A8C2LAU3", "url": "https://omabrowser.org/oma/group/A0A8C2LAU3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0Z8F0-1", "protein_name": "BICRA like chromatin remodeling complex associated protein", "gene_name": "GLTSCR1L", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MCNVVGARGLTATSVSRNSKDATRPTHAEPTKDSLNSVLLIASSLVMDDDDDESCLLDLIGDPQALNYFLHGPSSKSSNEDLTNAEYSVANSNSIFANSNNTDPKSSVKGVSSQLGEGPSDGLQLSSSLQFLEDELVSSPLPDLSEDQPFDILQKSLQEANITEQTLAEEAYLDASVGSSQQFAQAQLHPSSSASFTQASNVSNYSGQTLQPIGVTQVVQQPVGASFASNTVGVQHGFMQHVGISVPSQHLSNSNQISGSGQIQLIGSFSNQPSMMTINNLDGSQIILKGNGQQTPANMSSSLLVHRQTPNGNSLFGNSNTSPVAQPVTVPFNSTNFQTSVPVHNIIIQRGLAPNSNKVPVNIQPKPVQMGQQSAYNVNNLGIQQHHVQQGIPFASASSPQSSVVGPHMSVNIVNQQNTRKSVTPQTVSNAGGSIVIHSPMGQPHAPQNQFLIPTSLSVNSNSVHHVQAINGQLLQTQPSQLVPSQVSAEHVMLNRNSTNMLRANQSYSGQMLNNQNAAVQLVSGQTFTAPGNQVIVNHGTSQIVGGQVPLQQASPTVLHLSPSQANASQGRSSFTTMSPGQSTVSNMSASNRFAVVSSSGSVHPSLGPSVQSVASGGNFTGDQLTQNRTQVPISASHRLPASSSKSVSTFSHTSVGVTQQQFTFSQKKGMNQTSPVSASKAQDNLRQHQLSSLLSNTLSGQDSGGKIIQQSLGTSQEKGVGSSSVQCLQVDGHLVGQKRPAAKQLTKGAFMLQQLQKDQMQAVTPDKSQFRSLNDAVQRLLSYHVCQGSLPTEEDLRKVDSEFESVATQLLKRTQAMLNKYRCLLIEDAMRINPSAEMVMIDRMFNQEERASLTREKRLALVDPDGYQADFCCSAKQFDKTADEAQTSKSDHQSSKTLPSRSQTTKTQARDRPKSISAESTNHNKLPLVPNNILTSQEGTTKKSESLTKALKFEKANCSSGSQYKALSEEKMAGKVLSKSAENSLSSEDFSKAVSRGNHGTHNKISRNTVQSFSKLTCNNSFKDKTLRSPPKNEVLHPDNMKGSSEPQQDLLLSKSLETTFKNILELKKTGRPTQNEASSSGSVDLEFPNFSPLASQENCLEKFIPDHSEGVETDSVLEAAVNSILEC", "length": 1129 }, "evidence": [ { "id": "A0A8C2LAU3", "url": "https://omabrowser.org/oma/group/A0A8C2LAU3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ABK0L4W7-1", "protein_name": "BICRA like chromatin remodeling complex associated protein", "gene_name": "Bicral", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMTVPLQKEAQRAAAPLRPHCQSLCSDSLSSFLAVVMDDDDDSCLLDLIGDPQALNYFLHGPSSKSSGDDVTNAGYSAANSNSIFANSTNADPKSSLKGVSNQLGEGPSDGLPLASSLQFLEDELESSPLPDLSEDQPFDILQKSLQEANITEQTLAEEAYLDASIGSSQQFAQAQLHPSSSASFTQASNVSNYSGQTLQPIGVTHVPVGASFASNTVGVQHGFMQHVGISVPSQHLPNSSQISGSGQIQLIGSFGNQPSMMTINNLDGSQIILKGSGQQAPSSVSGGLLVHRQTPNGNSLFGNPTSSPGAQPVTVPFNSTNFQASLPVHNIIIQRGLAPNSNKVPINIQPKPIQMGQQSTYNVNSLGLQQHHVQQGISFASASSPQGSVVGPHMSVNIVNQQNARKPVTSQAVSSAGGSIVIHSPMGQPHTPQSQFLIPTSLSVSSNSVHHVQTINGQLVQTQPSQLISGQVASEHVMLNRNSSNMLRTNQPYAGQMLNNQSAAVQLVSGQTFATSGSPVIVNHASPQIVGGQMPLQQASPTVLHLSPGQSSVSQGRPGFATMASVSSMSGPARFPAVSSASTAHPTLGPAVQSGASGSNFTGDQLTQANRTPVPVSVSHRLPVSASKSPSTLSSTPGTQQQFFCQAPKKCLNQTAPIPTPIPTSKTTDSLRQPQIPGLLSTALPGQDCGSKIMPAPLGTTQPQQENSVGSSPSQTAVQVDSHSGQKRPAAKQLTKGAFILQQLQRDQAHAVTPDKSQFRSLTDTVQRLLSYHVCQGSMPTEEDLSKVDSEFEEVATQLLKRTHAMLNKYRSLLLEDAMRINPSAEMVMIDRMFNQEERASLSRDKRLALVDPEGFQADFCCSFKLDEAAPETPLDRSDQHRSKTSSLHQVPRAQSRDRAKPGVAEATNHDQFHLVPNHIVVSAEGNISKKSEGHSRTLKFDKGVLGQYRGPPEDKGGRRDPAKASGCSPGPEGHRKTLPRPDHGSESKLPGILASSHMEMPCLDSFQDKALRNSPKNEVLHTDIMKGSGEPQPDLQLTKSLEKTFKNILELKNAGRPQNDPAASGAVDLDFPSFSPMASQENCLEKFIPDHSEGVVETDSILEAAVNSILEC", "length": 1114 }, "evidence": [ { "id": "A0A8C2LAU3", "url": "https://omabrowser.org/oma/group/A0A8C2LAU3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6AI39-1", "protein_name": "BRD4-interacting chromatin-remodeling complex-associated protein-like", "gene_name": "BICRAL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDDDDDSCLLDLIGDPQALNYFLHGPSNKSSNDDLTNAGYSAANSNSIFANSSNADPKSSLKGVSNQLGEGPSDGLPLSSSLQFLEDELESSPLPDLTEDQPFDILQKSLQEANITEQTLAEEAYLDASIGSSQQFAQAQLHPSSSASFTQASNVSNYSGQTLQPIGVTHVPVGASFASNTVGVQHGFMQHVGISVPSQHLSNSSQISGSGQIQLIGSFGNHPSMMTINNLDGSQIILKGSGQQAPSNVSGGLLVHRQTPNGNSLFGNSSSSPVAQPVTVPFNSTNFQTSLPVHNIIIQRGLAPNSNKVPINIQPKPIQMGQQNTYNVNNLGIQQHHVQQGISFASASSPQGSVVGPHMSVNIVNQQNTRKPVTSQAVSSTGGSIVIHSPMGQPHAPQSQFLIPTSLSVSSNSVHHVQTINGQLLQTQPSQLISGQVASEHVMLNRNSSNMLRTNQPYTGPMLNNQNTAVHLVSGQTFAASGSPVIANHASPQLVGGQMPLQQASPTVLHLSPGQSSVSQGRPGFATMPSVTSMSGPSRFPAVSSASTAHPSLGSAVQSGSSGSNFTGDQLTQPNRTPVPVSVSHRLPVSSSKSTSTFSNTPGTGTQQQFFCQAQKKCLNQTSPISAPKTTDGLRQAQIPGLLSTTLPGQDSGSKVISASLGTAQPQQEKVVGSSPGHPAVQVESHSGGQKRPAAKQLTKGAFILQQLQRDQAHTVTPDKSHFRSLSDAVQRLLSYHVCQGSMPTEEDLRKVDNEFETVATQLLKRTQAMLNKYRCLLLEDAMRINPSAEMVMIDRMFNQEERASLSRDKRLALVDPEGFQADFCCSFKLDKAAHETQFGRSDQHGSKASSSLQPPAKAQGRDRAKTGVTEPMNHDQFHLVPNHIVVSAEGNISKKTECLGRALKFDKVGLVQYQSTSEEKASRREPLKASQCSPGPEGHRKTSSRSDHGTESKLSSILADSHLEMTCNNSFQDKSLRNSPKNEVLHTDIMKGSGEPQPDLQLTKSLETTFKNILELKKAGRQPQSDPTVSGSVELDFPNFSPMASQENCLEKFIPDHSEGVVETDSILEAAVNSILEC", "length": 1079 }, "evidence": [ { "id": "A0A8C2LAU3", "url": "https://omabrowser.org/oma/group/A0A8C2LAU3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CHH5-1", "protein_name": "BRD4-interacting chromatin-remodeling complex-associated protein-like", "gene_name": "Bicral", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDDDDDSCLLDLIGDPQALNYFLHGPSSKSGSDDVTNAGYSAANSNSIFANSTNADPKSALKGVSDQLGEGPSDGLPLASSLQFLEDELESSPLPDLSEDQPFDILQKSLQEANITEQTLAEEAYLDASIGSSQQFAQAQLHPSSSASFTQASNVSNYSGQTLQPIGVTHVPVGASFASNTVGVQHGFMQHVGISVPSQHLPNSSQISGSGQIQLIGSFGNQPSMMTINNLDGSQIILKGSGQQAPSNVSGGLLVHRQTPNGNSLFGNSTSSPVAQPVTVPFNSTNFQASLPVHNIIIQRGLAPNSNKVPINIQPKPVQMGQQSAYNVNNLGIQQHHAQQGISFAPTSSPQGSVVGPHMSVNIVNQQNTRKPVTSQAVSGTGGSIVIHSPMGQPHTPQSQFLIPTSLSVSSNSVHHVQAINGQLLQTQPSQLISGQVASEHVMLNRNSSNMLRTNQPYSGQMLNNQNTAVQLVSGQTFATSGSPVIVNHASPQIVGGQMPLQQASPTVLHLSPGQSSVSQGRPGFATMPAVSGMAGPARFPAVSSASTAHPTLGPTVQSGAPGSNFTGDQLTQANRTPAPVSVSHRLPVSASKSPSTLSNTPGTQQQFFCQAQKKCLNQTSPIPTSKTTDGLRPSQIPGLLSTALPGQDSGSKIMPATLGATQAQPESSVGSSPSQTAVQVDSHPGQKRPAAKQLTKGAFILQQLQRDQAHAVTPDKSQFRSLNDTVQRLLSYHVCQGSMPTEEDLRQVDNEFEEVATQLLKRTQAMLNKYRFLLLEDAMRINPSAEMVMIDRMFNQEERASLSRDKRLALVDPEGFQADFCCSFKLDEAVPETPLDRSDQHRSKTSSLHQVPRAQSRDRAKPGMAEATNHDQFHLVPNHIVVSAEGNISKKSEGHSRTLKFDRGVLGQYRGPPEDKGGRRDPAKVSRCSPGPEGHRKSLPRPDHGSESKLPGVLASSHMEMPCLDSFQDKALRNSPKNEVLHTDIMKGSGEPQPDLQLTKSLEKTFKNILELKNSGRPPSDPTASGAADLDFPSFSPMASQENCLEKFIPDHSEGVVETDSILEAAVNSILEC", "length": 1074 }, "evidence": [ { "id": "A0A8C2LAU3", "url": "https://omabrowser.org/oma/group/A0A8C2LAU3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "SWI/SNF complex", "id": "GO:0016514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016514", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LAU3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAU3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LAU3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAU3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 157, "end_pos": 159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 248, "end_pos": 250, "annotation": "n_glycosylation_sequon" }, { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" }, { "start_pos": 28, "end_pos": 30, "annotation": "n_glycosylation_sequon" }, { "start_pos": 447, "end_pos": 449, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" }, { "start_pos": 565, "end_pos": 567, "annotation": "n_glycosylation_sequon" }, { "start_pos": 575, "end_pos": 577, "annotation": "n_glycosylation_sequon" }, { "start_pos": 925, "end_pos": 927, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LAU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAU3" }, { "id": "PF15249", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15249" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GLTSCR protein conserved", "eco_id": "ECO_0000259", "start_pos": 708, "end_pos": 808, "start_aa": "Asp", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 114, "end_pos": 116 }, { "start_pos": 154, "end_pos": 156 }, { "start_pos": 157, "end_pos": 159 }, { "start_pos": 203, "end_pos": 205 }, { "start_pos": 248, "end_pos": 250 }, { "start_pos": 268, "end_pos": 270 }, { "start_pos": 283, "end_pos": 285 }, { "start_pos": 28, "end_pos": 30 }, { "start_pos": 447, "end_pos": 449 }, { "start_pos": 51, "end_pos": 53 }, { "start_pos": 565, "end_pos": 567 }, { "start_pos": 575, "end_pos": 577 }, { "start_pos": 925, "end_pos": 927 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LAV3-1", "uniprot_ac": "A0A8C2LAV3", "uniprot_id": "A0A8C2LAV3_CRIGR", "mass": { "chemical_mass": 8937.0, "monoisotopic_mass": 8937.0 }, "refseq": { "ac": "XP_003504608", "name": "protein GPR15L isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504608" }, "gene_names": [ { "name": "CUNH10orf99", "type": "recommended", "evidence": [ { "id": "A0A8C2LAV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAV3" } ] }, { "name": "CUNH10orf99", "type": "synonym", "evidence": [ { "id": "XP_003504608", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504608" } ] } ], "protein_names": [ { "name": "Protein GPR15L isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8C2LAV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAV3/entry#names_and_taxonomy" } ] }, { "name": "protein GPR15L isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003504608", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504608" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614076.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003504608", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504608" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LAV3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAV3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "CUNH10orf99", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAV3", "locus": {} } ], "crossref": [ { "id": "100753638", "url": "https://www.ncbi.nlm.nih.gov/gene/100753638", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031713", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031713", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753638", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753638", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RARLCCH", "url": "https://omabrowser.org/oma/group/RARLCCH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LAV3", "url": "https://www.orthodb.org/?gene=A0A8C2LAV3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF15854", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15854", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003504608", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504608", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LAV3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LAV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAV3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLLVICSLLCMLLLSFCVLSSEGKRHRLRPSKFKPCCYLTHRSKLTPQKGHHTRPCRPCRIKPPSKTWVVPGALPQV", "length": 78, "header": "tr|A0A8C2LAV3-1|A0A8C2LAV3_CRIGR Isoform 1 of Protein GPR15L isoform X1 OS=Cricetulus griseus OX=10029 GN=CUNH10orf99 PE=4 SV=1 CANONICAL=A0A8C2LAV3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LAV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LAV3/entry#A0A8C2LAV3-1", "sequence": { "sequence": "MRLLVICSLLCMLLLSFCVLSSEGKRHRLRPSKFKPCCYLTHRSKLTPQKGHHTRPCRPCRIKPPSKTWVVPGALPQV", "length": 78, "header": "tr|A0A8C2LAV3-1|A0A8C2LAV3_CRIGR Isoform 1 of Protein GPR15L isoform X1 OS=Cricetulus griseus OX=10029 GN=CUNH10orf99 PE=4 SV=1 CANONICAL=A0A8C2LAV3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027259533", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259533" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LB43", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LB43" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Fbxo15", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LB43", "locus": {} } ], "crossref": [ { "id": "cd22093", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22093", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100750915", "url": "https://www.ncbi.nlm.nih.gov/gene/100750915", "database": "GeneID", "categories": [ "Genome 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JIB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JIB6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSEQRAGVRMTGASDGSRSRKCPGRGWGRKGGGGRGGTQPTDARAWPRFCARASGGASTPPLRAAGRKGPGVKFARGSPVLRQYTRRGQHNEKSTICFVSLDRMPTEVLLNIFSYLDAVSLLCTGCVSRRFYHLASDNLIWIKIYSAAFSPKRSHWKVNSVEETATSVSLLSVEDKEAGYWKKEYITKQISDVKEALAQIVKPVNSYTGLPVKIKEALRVFGLHFAIILREKSGKEHVMQHVDLSFNDTSVTVVWYDKNWPHLAKLSTLDLCGVTPVFADRYKTFDPYGPRWLSLIAQYDLSHLSKAAMIGCDRLVRVFCLNPGLLVGLWQKGDGLAFVMANLHFHRLVERSTLGSITLPYVPPPHHSPFVDDSPDYGLQGYQLHIDMHGGGTFYLCSTLYTLFSSKECIENGYAKFMVINLNNNREHLPLIGKVGLTWRTTIFDGFIESCSFMDLTLLEEYRKPFWCVSSPVYLRSIAYPSDGPHFLGHTYCVDYMDTEGGVHVELVWIEETEEYFIISLVLYLSVAKINHWFGTKY", "length": 539, "header": "tr|A0A8C2LB43-1|A0A8C2LB43_CRIGR Isoform 1 of F-box only protein 15 isoform X5 OS=Cricetulus griseus OX=10029 GN=Fbxo15 PE=4 SV=1 CANONICAL=A0A8C2LB43-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LB43-1", "url": 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"MATGRGRMLRQGCLGLQALRGSLHGGGAAWGSAGAAAGRTGFRKGPGVKFARGSPVLRQYTRRGQHNEKSTICFVSLDRMPTEVLLNIFSYLDAVSLLCTGCVSRRFYHLASDNLIWIKIYSAAFSPKRSHWKVNSVEETATSVSLLSVEDKEAGYWKKEYITKQISDVKEALAQIVKPVNSYTGLPVKIKEALRVFGLHFAIILREKSGKEHVMQHVDLSFNDTSVTVVWYDKNWPHLAKLSTLDLCGVTPVFADRYKTFDPYGPRWLSLIAQYDLSHLSKAAMIGCDRLVRVFCLNPGLLVGLWQKGDGLAFVMANLHFHRLVERSTLGSITLPYVPPPHHSPFVDDSPDYGLQGYQLHIDMHGGGTFYLCSTLYTLFSSKECIENGYAKFMVINLNNNREHLPLIGKVGLTWRTTIFDGFIESCSFMDLTLLEEYRKPFWCVSSPVYLRSIAYPSDGPHFLGHTYCVDYMDTEGGVHVELVWIEETEEYFIISLVLYLSVAKINHWFGTKY", "length": 514, "header": "tr|A0A9J7FG62-1|A0A9J7FG62_CRIGR Computationally mapped isoform of F-box only protein 15 isoform X6 OS=Cricetulus griseus OX=10029 GN=Fbxo15 PE=4 SV=1 CANONICAL=A0A8C2LB43-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FJV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LB43/entry#A0A9J7FJV3-1", "sequence": { "sequence": "MSSEQRAGVRMTGASDGSRSRKCPGRGWGRKGGGGRGGTQPTDARAWPRFCARASGGASTPPLRAAGRKGPGVKFARGSPVLRQYTRRGQHNEKSTICFVSLDRMPTEVLLNIFSYLDAVSLLCTGCVSRRFYHLASDNLIWIKIYSAAFSPKRSHWKVNSVEETATSVSLLSVEDKEAGYWKKEYITKQISDVKEALAQIVKPVNSYTGLPVKIKEALRVFGLHFAIILREKSGKEHVMQHVDLSFNDTSVTVVWYDKNWPHLAKLSTLDLCGVTPVFADRYKTFDPYGPRWLSLIAQYDLSHLSKAAMIGCDRLVRVFCLNPGLLVGLWQKGDGLAFVMANLHFHRLVERSTLGSITLPYVPPPHHSPFVDDSPDYGLQGYQLHIDMHGGGTFYLCSTLYTLFSSKAVVACTGPAQHSWYQPVMGFGEEPVRPSCSMLKYWLLMDSG", "length": 449, "header": "tr|A0A9J7FJV3-1|A0A9J7FJV3_CRIGR Computationally mapped isoform of F-box only protein 15 isoform X11 OS=Cricetulus griseus OX=10029 GN=Fbxo15 PE=4 SV=1 CANONICAL=A0A8C2LB43-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FK44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LB43/entry#A0A9J7FK44-1", "sequence": { "sequence": "MSSEQRAGVRMTGASDGSRSRKCPGRGWGRKGGGGRGGTQPTDARAWPRFCARASGGASTPPLRAAGRKGPGVKFARGSPVLRQYTRRGQHNEKSTICFVSLDRMPTEVLLNIFSYLDAVSLLCTGCVSRRFYHLASDNLIWIKIYSAAFSPKRSHWKVNSVEETATSVSLLSVEDKEAGYWKKEYITKQISDVKEALAQIVKPVNSYTGLPVKIKEALRVFGLHFAIILREKSGKEHVMQHVDLSFNDTSVTVVWYDKNWPHLAKLSTLDLCGVTPVFADRYKTFDPYGPRWLSLIAQYDLSHLSKAAMIGCDRLVRVFCLNPGLLVGLWQKGDGLAFVMANLHFHRLVERSTLGSITLPYVPPPHHSPFVDDSPDYGLQGYQLHIDMHGGGTFYLCSTLYTLFSSKAAVVACTGPAQHSWYQPVMGFGEEPVRPSCSMLKYWLLMDSG", "length": 450, "header": "tr|A0A9J7FK44-1|A0A9J7FK44_CRIGR Computationally mapped isoform of F-box only protein 15 isoform X10 OS=Cricetulus griseus OX=10029 GN=Fbxo15 PE=4 SV=1 CANONICAL=A0A8C2LB43-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FKW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LB43/entry#A0A9J7FKW0-1", "sequence": { "sequence": "MSSEQRAGVRMTGASDGSRSRKCPGRGWGRKGGGGRGGTQPTDARAWPRFCARASGGASTPPLRAAGRKGPGVKFARGSPVLRQYTRRGQHNEKSTICFVSLDSLIWIKIYSAAFSPKRSHWKVNSVEETATSVSLLSVEDKEAGYWKKEYITKQISDVKEALAQIVKPVNSYTGLPVKIKEALRVFGLHFAIILREKSGKEHVMQHVDLSFNDTSVTVVWYDKNWPHLAKLSTLDLCGVTPVFADRYKTFDPYGPRWLSLIAQYDLSHLSKAAMIGCDRLVRVFCLNPGLLVGLWQKGDGLAFVMANLHFHRLVERSTLGSITLPYVPPPHHSPFVDDSPDYGLQGYQLHIDMHGGGTFYLCSTLYTLFSSKECIENGYAKFMVINLNNNREHLPLIGKVGLTWRTTIFDGFIESCSFMDLTLLEEYRKPFWCVSSPVYLRSIAYPSDGPHFLGHTYCVDYMDTEGGVHVELVWIEETEEYFIISLVLYLSVAKINHWFGTKY", "length": 504, "header": "tr|A0A9J7FKW0-1|A0A9J7FKW0_CRIGR Computationally mapped isoform of F-box only protein 15 isoform X7 OS=Cricetulus griseus OX=10029 GN=Fbxo15 PE=4 SV=1 CANONICAL=A0A8C2LB43-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GSJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LB43/entry#A0A9J7GSJ3-1", "sequence": { "sequence": "MATGRGRMLRQGCLGLQALRGSLHGGGAAWGSAGAAAGRTGFRKGPGVKFARGSPVLRQYTRRGQHNEKSTICFVSLDSLIWIKIYSAAFSPKRSHWKVNSVEETATSVSLLSVEDKEAGYWKKEYITKQISDVKEALAQIVKPVNSYTGLPVKIKEALRVFGLHFAIILREKSGKEHVMQHVDLSFNDTSVTVVWYDKNWPHLAKLSTLDLCGVTPVFADRYKTFDPYGPRWLSLIAQYDLSHLSKAAMIGCDRLVRVFCLNPGLLVGLWQKGDGLAFVMANLHFHRLVERSTLGSITLPYVPPPHHSPFVDDSPDYGLQGYQLHIDMHGGGTFYLCSTLYTLFSSKECIENGYAKFMVINLNNNREHLPLIGKVGLTWRTTIFDGFIESCSFMDLTLLEEYRKPFWCVSSPVYLRSIAYPSDGPHFLGHTYCVDYMDTEGGVHVELVWIEETEEYFIISLVLYLSVAKINHWFGTKY", "length": 479, "header": "tr|A0A9J7GSJ3-1|A0A9J7GSJ3_CRIGR Computationally mapped isoform of F-box only protein 15 isoform X9 OS=Cricetulus griseus OX=10029 GN=Fbxo15 PE=4 SV=1 CANONICAL=A0A8C2LB43-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JIB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LB43/entry#A0A9J7JIB6-1", "sequence": { "sequence": "MSSEQRAGVRMTGASDGSRSRKCPGRGWGRKGGGGRGGTQPTDARAWPRFCARASGGASTPPLRAAGRKGPGVKFARGSPVLRQYTRRGQHNEKSTICFVSLDRMPTEVLLNIFSYLDAVSLLCTGCVSRRFYHLASDNLIWIKIYSAAFSPKRSHWKVNSVEETATSVSLLSVEDKEAGYWKKEYITKQISDVKEALAQIVKPVNSYTGLPVKIKEALRVFGLHFAIILREKSGKEHVMQHVDLSFNDTSVTVVWYDKNWPHLAKLSTLDLCGVTPVFADRYKTFDPYGPRWLSLIAQYDLSHLSKAAMIGCDRLVRVFCLNPGLLVGLWQKGDGLAFVMANLHFHRLVERSTLGSITLPYVPPPHHSPFVDDSPDYGLQGYQLHIDMHGGGTFYLCSTLYTLFSSKECIENGYAKFMVINLNNNREHLPLIGKVGLTWRTTIFDGFIENCGDRDPRPGAGFLWSLTFRPFGIGDLPCLSEQILTLGKNRICHI", "length": 495, "header": "tr|A0A9J7JIB6-1|A0A9J7JIB6_CRIGR Computationally mapped isoform of F-box only protein 15 isoform X8 OS=Cricetulus griseus OX=10029 GN=Fbxo15 PE=4 SV=1 CANONICAL=A0A8C2LB43-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LB43", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LB43" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LB43", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LB43" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100750915", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100750915", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LB43", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LB43" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 248, "end_pos": 250, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LB43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LB43" }, { "id": "PS50181", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50181" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-box", "eco_id": "ECO_0000259", "start_pos": 99, "end_pos": 145, "start_aa": "Phe", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 248, "end_pos": 250 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LBT0-1", "uniprot_ac": "A0A8C2LBT0", "uniprot_id": "A0A8C2LBT0_CRIGR", "mass": { "chemical_mass": 39978.0, "monoisotopic_mass": 39978.0 }, "refseq": { "ac": "XP_027284773", "name": "probable G-protein coupled receptor 27 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284773" }, "gene_names": [ { "name": "Gpr27", "type": "recommended", "evidence": [ { "id": "A0A8C2LBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LBT0" } ] }, { "name": "Gpr27", "type": "synonym", "evidence": [ { "id": "XP_027284773", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284773" } ] } ], "protein_names": [ { "name": "Probable G-protein coupled receptor 27 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A8C2LBT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LBT0/entry#names_and_taxonomy" } ] }, { "name": "probable G-protein coupled receptor 27 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027284773", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284773" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027284773", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284773" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LBT0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LBT0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Gpr27", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LBT0", "locus": {} } ], "crossref": [ { "id": "103162514", "url": "https://www.ncbi.nlm.nih.gov/gene/103162514", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051509", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051509", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:103162514", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103162514", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LBT0", "url": "https://www.orthodb.org/?gene=A0A8C2LBT0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19268", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19268", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19268:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19268:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027284773", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284773", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LBT0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LBT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LBT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LBT0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MANASEPGGGGGGGGAEAAALGLRLATLSLLLCVSLAGNVLFALLIVRERSLHRAPYYLLLDLCLADGLRALACLPAVMLAARRAAAAAGTPPGALGCKLLAFLAALFCFHAAFLLLGVGVTRYLAIAHHRFYAERLAGWPCAAMLVCAAWALALAAAFPPVLDGGGADDEDAPCALEQRPDGAPGALGFLLLLAAVVGATHLVYLRLLFFIHDRRKMRPARLVPAVSHDWTFHGPGATGQAAANWTAGFGRGPTPPALVGIRPAGPGRGARRLLVLEEFKTEKRLCKMFYAITLLFLLLWGPYVVASYLRVLVQPGAVPQAYLTASVWLTFAQAGINPVVCFLFNRELRDCFRAQFPCCQSPQATQATLPCDLKGIGL", "length": 379, "header": "tr|A0A8C2LBT0-1|A0A8C2LBT0_CRIGR Isoform 1 of Probable G-protein coupled receptor 27 isoform X2 OS=Cricetulus griseus OX=10029 GN=Gpr27 PE=4 SV=1 CANONICAL=A0A8C2LBT0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LBT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LBT0/entry#A0A8C2LBT0-1", "sequence": { "sequence": "MANASEPGGGGGGGGAEAAALGLRLATLSLLLCVSLAGNVLFALLIVRERSLHRAPYYLLLDLCLADGLRALACLPAVMLAARRAAAAAGTPPGALGCKLLAFLAALFCFHAAFLLLGVGVTRYLAIAHHRFYAERLAGWPCAAMLVCAAWALALAAAFPPVLDGGGADDEDAPCALEQRPDGAPGALGFLLLLAAVVGATHLVYLRLLFFIHDRRKMRPARLVPAVSHDWTFHGPGATGQAAANWTAGFGRGPTPPALVGIRPAGPGRGARRLLVLEEFKTEKRLCKMFYAITLLFLLLWGPYVVASYLRVLVQPGAVPQAYLTASVWLTFAQAGINPVVCFLFNRELRDCFRAQFPCCQSPQATQATLPCDLKGIGL", "length": 379, "header": "tr|A0A8C2LBT0-1|A0A8C2LBT0_CRIGR Isoform 1 of Probable G-protein coupled receptor 27 isoform X2 OS=Cricetulus griseus OX=10029 GN=Gpr27 PE=4 SV=1 CANONICAL=A0A8C2LBT0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 255, "start_aa": "Thr", "end_pos": 255, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr255", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NW_003615934.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003513505", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003513505" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LCG5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCG5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Prss33", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCG5", "locus": {} } ], "crossref": [ { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100772402", "url": "https://www.ncbi.nlm.nih.gov/gene/100772402", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772402", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772402", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DARTCDR", "url": "https://omabrowser.org/oma/group/DARTCDR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LCG5", "url": "https://www.orthodb.org/?gene=A0A8C2LCG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24253", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24253", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24253:SF58", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24253:SF58", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003513505", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003513505", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LCG5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LCG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCG5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGASHLQILFLLVLGARMQRCAACGQPRMSSRIVGGRDAGDGEWPWQTSIQHRGVHVCGGSLVAPQWVLTAAHCFPRRVVPSEYSVLLGALSLGVTSSHELLVPVLRVLLPPDYSEDEARGDLALLQLRHPVSLSARIQPVCLPAPGSHPPPGSPCWVTGWGSLSPGVPLPEGRPLQGVRVPLLDSGACDRLYHVGANVPQGERIVLPGNLCAGYRRGHKDACQGDSGGPLTCLQSGRWVLVGVVSWGKGCALPNRPGVYTNVAKYSPWIQAHLRL", "length": 277, "header": "tr|A0A8C2LCG5-1|A0A8C2LCG5_CRIGR Isoform 1 of Serine protease 33 OS=Cricetulus griseus OX=10029 GN=Prss33 PE=4 SV=1 CANONICAL=A0A8C2LCG5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LCG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LCG5/entry#A0A8C2LCG5-1", "sequence": { "sequence": "MRGASHLQILFLLVLGARMQRCAACGQPRMSSRIVGGRDAGDGEWPWQTSIQHRGVHVCGGSLVAPQWVLTAAHCFPRRVVPSEYSVLLGALSLGVTSSHELLVPVLRVLLPPDYSEDEARGDLALLQLRHPVSLSARIQPVCLPAPGSHPPPGSPCWVTGWGSLSPGVPLPEGRPLQGVRVPLLDSGACDRLYHVGANVPQGERIVLPGNLCAGYRRGHKDACQGDSGGPLTCLQSGRWVLVGVVSWGKGCALPNRPGVYTNVAKYSPWIQAHLRL", "length": 277, "header": "tr|A0A8C2LCG5-1|A0A8C2LCG5_CRIGR Isoform 1 of Serine protease 33 OS=Cricetulus griseus OX=10029 GN=Prss33 PE=4 SV=1 CANONICAL=A0A8C2LCG5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"url": "https://omabrowser.org/oma/group/A0A8C2LCG5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80WM7-1", "protein_name": "Serine protease 33", "gene_name": "Prss33", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRGASHLQILLLLVLGTRMQECAACGQPRMSSRIVGGRDAQDGEWPWQTSIQHRGAHVCGGSLIAPQWVLTAGHCFPRRVWPSEYSVLLGALSLDVRSSHELLVPVLRVLLPPDYSEDEARGDLALLQLRHPVSLSTRIQPVCLPAPGSHPPPGSPCWVTGWGSLSPGVPLPKGRPLQGVRVPLLDSRACDRLYHVGANVPQGERIVLPGNLCAGYRRGHKDACQGDSGGPLTCMESGHWVLVGVVSWGKGCALPNRPGVYTNVAKYSPWIQARLSL", "length": 277 }, "evidence": [ { "id": "A0A8C2LCG5", "url": "https://omabrowser.org/oma/group/A0A8C2LCG5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NF86-1", "protein_name": "Serine protease 33", "gene_name": "PRSS33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"url": "https://www.uniprot.org/uniprotkb/A0A9J7H5W3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H5W3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H5W3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBQ2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRLRGCCARPRGGAPVRAERSRASSRALRVLVDMDGVLADFEGGFLRKFRARFPDLPFVALEDRRGFWVSEQYGRLQPGLSEKAVSIWESKDFFFELEPLPGAVEAVKQMANLQNTDVFICTSPIKMIKYCPYEKGLLLHTVHYAWVEKHFGPDFLEQIVLTRDKTVVSADLLIDDRPDITGAEPHPSWEHILFTSCHNHHLQLKPPRRRLHSWADDWKAILDSKRPR", "length": 229, "header": "tr|A0A8C2LD69-1|A0A8C2LD69_CRIGR Isoform 1 of 5'(3')-deoxyribonucleotidase, mitochondrial isoform X2 OS=Cricetulus griseus OX=10029 GN=Nt5m PE=3 SV=1 CANONICAL=A0A8C2LD69-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LD69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LD69/entry#A0A8C2LD69-1", "sequence": { "sequence": "MLRLRGCCARPRGGAPVRAERSRASSRALRVLVDMDGVLADFEGGFLRKFRARFPDLPFVALEDRRGFWVSEQYGRLQPGLSEKAVSIWESKDFFFELEPLPGAVEAVKQMANLQNTDVFICTSPIKMIKYCPYEKGLLLHTVHYAWVEKHFGPDFLEQIVLTRDKTVVSADLLIDDRPDITGAEPHPSWEHILFTSCHNHHLQLKPPRRRLHSWADDWKAILDSKRPR", "length": 229, "header": "tr|A0A8C2LD69-1|A0A8C2LD69_CRIGR Isoform 1 of 5'(3')-deoxyribonucleotidase, mitochondrial isoform X2 OS=Cricetulus griseus OX=10029 GN=Nt5m PE=3 SV=1 CANONICAL=A0A8C2LD69-1" }, "locus": {} }, { "isoform_ac": "A0A8C2QCF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LD69/entry#A0A8C2QCF2-1", "sequence": { "sequence": "MLRLRGCCARPRGGAPVRAERSRASSRALRVLVDMDGVLADFEGGFLRKFRARFPDLPFVALEDRRGFWVSEQYGRLQPGLSEKAVSIWESKDFFFELEPLPGAVEAVKQMANLQNTDVFICTSPIKMIKYCPYEKYAWVEKHFGPDFLEQIVLTRDKTVVSADLLIDDRPDITGAEPHPSWEHILFTSCHNHHLQLKPPRRRLHSWADDWKAILDSKRPR", "length": 221, "header": "tr|A0A8C2QCF2-1|A0A8C2QCF2_CRIGR Computationally mapped isoform of 5'(3')-deoxyribonucleotidase, mitochondrial isoform X3 OS=Cricetulus griseus OX=10029 GN=Nt5m PE=3 SV=1 CANONICAL=A0A8C2LD69-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H5W3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LD69/entry#A0A9J7H5W3-1", "sequence": { "sequence": "MLRLRGCCARPRGGAPVRAERSRASSRALRVLVDMDGVLADFEGGFLRKFRARFPDLPFVALEDRRGFWVSEQYGRLQPGLSEKAVSIWESKDFFFELEPLPGAVEAVKQMANLQNTDVFICTSPIKMIKYCPYEKYAWVEKHFGPDFLEQIVLTRDKTVVSADLLIDDRPDITANDPFSEKKANRTLGSLN", "length": 192, "header": "tr|A0A9J7H5W3-1|A0A9J7H5W3_CRIGR Computationally mapped isoform of 5'(3')-deoxyribonucleotidase, mitochondrial isoform X5 OS=Cricetulus griseus OX=10029 GN=Nt5m PE=4 SV=1 CANONICAL=A0A8C2LD69-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KBQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LD69/entry#A0A9J7KBQ2-1", "sequence": { "sequence": "MLRLRGCCARPRGGAPVRAERSRASSRALRVLVDMDGVLADFEGGFLRKFRARFPDLPFVALEDRRGFWVSEQYGRLQPGLSEKAVSIWESKDFFFELEPLPGAVEAVKQMANLQNTDVFICTSPIKMIKYCPYEKGLLLHTVHYAWVEKHFGPDFLEQIVLTRDKTVVSADLLIDDRPDITANDPFSEKKANRTLGSLN", "length": 200, "header": "tr|A0A9J7KBQ2-1|A0A9J7KBQ2_CRIGR Computationally mapped isoform of 5'(3')-deoxyribonucleotidase, mitochondrial isoform X4 OS=Cricetulus griseus OX=10029 GN=Nt5m PE=4 SV=1 CANONICAL=A0A8C2LD69-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LD69", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LD69" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"A0A8C2LD69", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LD69" } ], "pmid": "" }, { "name": "UMP catabolic process", "id": "GO:0046050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046050", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LD69", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LD69" } ], "pmid": "" }, { "name": "dTMP catabolic process", "id": "GO:0046074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046074", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LD69", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LD69" } ], "pmid": "" }, { "name": "dGMP catabolic process", "id": "GO:0046055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046055", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LD69", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LD69" } ], "pmid": "" }, { "name": "TMP catabolic process", "id": "GO:0046045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046045", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LD69", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LD69" } ], "pmid": "" }, { "name": "pyrimidine deoxyribonucleotide catabolic process", "id": "GO:0009223", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009223", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LD69", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LD69" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "3'-nucleotidase activity", "id": "GO:0008254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008254", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LD69", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LD69" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LD69", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LD69" } ], "pmid": "" }, { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LD69", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LD69" } ], "pmid": "" }, { "name": "5'-nucleotidase activity", "id": "GO:0008253", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008253", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LD69", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LD69" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LD69", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LD69" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], 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analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035299329", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299329" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LDC8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDC8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Wdr72", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDC8", "locus": {} } ], "crossref": [ { "id": "100766058", "url": "https://www.ncbi.nlm.nih.gov/gene/100766058", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] 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Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YHCSSRM", "url": "https://omabrowser.org/oma/group/YHCSSRM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LDC8", "url": "https://www.orthodb.org/?gene=A0A8C2LDC8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44099", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44099", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44099:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44099:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23123", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23123", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035299329", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035299329", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LDC8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LDC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDC8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZA9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZA9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSALQAVALWGRKAPPHSITAIMITDDQQTIVTGSQEGQLCLWSLSPELKISAKELLFGHSASVTCLAKARDFSKQPYVVSAAENGEMYVWNVSSGQCVEKATLPYRHTAICYYHCSSRMTGDGWLLCCGEYQDVLIIDAGTLAFLHTFSSSQSPDWMKCMCIVHSVRIQEDSLLVVSVTGELKVWDLSSSINSVQEKQDVYEKESKFLDSVNCQTIRFCTYTERLLLVVFSKCWKVYDYCDFSLLWTEVSRDGQFFAGGEVLAAHRVLVWTEDGHSYIYQLLNRWAQMGAAFRTFSGLSKCICPADGGVLKETIYPHLLCSTSVEENQSLHFVMGYMNERKEPFYKVLFSGEVSGRITLWHIPDVPISKFDGSPREIPVTTTWTLQDNFDKHQTVSQSITDHFSGSRDETGMTATITSSEYIPNLDKLICGCEDGTIFITKALNAAKAGLLEGDSLLRDPPCHALLRGHHQSVTSLLYPHGLASKLDESWMVSGDQGSCVILWDIFKEEILHTFSLESGPVTRLLMSPENLKISDGQILCCVCGDHSVALLHLEGRQCLLRARKHLFPVRTIRWHPVENFLIVGCADDSVYIWEIETGTLERHETGERARIILNCGDNVQFVKSEPTLPVASETHKHKSVEQRSSNAHQPGLVPCPVLQLESSCKVADTTSVPRPFNVLPVKTKWSHIGFHVLLFDLENLVELLLPTPINDVDHSGSFYGSDILRRAKSTVEKKTLTMRRNKASCSSLQAEAQAKPSGDSLPPGDNASKLPEESDGIKRQKKMKSSKKTRPKPSRKVDASFTIDMAKLFLSCVLPWGVDKELDSLCTRHLSILKLQGPVSLGLASNENLFSLMLPGWDACSTEIKEHSGINLFSRKVLELSNKYTATLPNQTGIPRGPDNHCDALQQSDTIVYLLNRLFLVNKLVNMPLDLACETDRPFKVESVHNKGKFPGSDILNISSFYGHLRNGRNEYHTPEVDISLLKLISCWRDQAVQVTEAIQAVLLAEVQQHMKHLKNTPISSQPDPVAEHTICERMLISSKVGWNEEIELPYVGNSYPPKTSVSPVKHGNDLNSANFQDTEDILDRCVLEESESAGQPRRRPWIAQVCSCRMC", "length": 1114, "header": "tr|A0A8C2LDC8-1|A0A8C2LDC8_CRIGR Isoform 1 of WD repeat-containing protein 72 isoform X1 OS=Cricetulus griseus OX=10029 GN=Wdr72 PE=4 SV=1 CANONICAL=A0A8C2LDC8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LDC8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDC8/entry#A0A8C2LDC8-1", "sequence": { "sequence": "MRSALQAVALWGRKAPPHSITAIMITDDQQTIVTGSQEGQLCLWSLSPELKISAKELLFGHSASVTCLAKARDFSKQPYVVSAAENGEMYVWNVSSGQCVEKATLPYRHTAICYYHCSSRMTGDGWLLCCGEYQDVLIIDAGTLAFLHTFSSSQSPDWMKCMCIVHSVRIQEDSLLVVSVTGELKVWDLSSSINSVQEKQDVYEKESKFLDSVNCQTIRFCTYTERLLLVVFSKCWKVYDYCDFSLLWTEVSRDGQFFAGGEVLAAHRVLVWTEDGHSYIYQLLNRWAQMGAAFRTFSGLSKCICPADGGVLKETIYPHLLCSTSVEENQSLHFVMGYMNERKEPFYKVLFSGEVSGRITLWHIPDVPISKFDGSPREIPVTTTWTLQDNFDKHQTVSQSITDHFSGSRDETGMTATITSSEYIPNLDKLICGCEDGTIFITKALNAAKAGLLEGDSLLRDPPCHALLRGHHQSVTSLLYPHGLASKLDESWMVSGDQGSCVILWDIFKEEILHTFSLESGPVTRLLMSPENLKISDGQILCCVCGDHSVALLHLEGRQCLLRARKHLFPVRTIRWHPVENFLIVGCADDSVYIWEIETGTLERHETGERARIILNCGDNVQFVKSEPTLPVASETHKHKSVEQRSSNAHQPGLVPCPVLQLESSCKVADTTSVPRPFNVLPVKTKWSHIGFHVLLFDLENLVELLLPTPINDVDHSGSFYGSDILRRAKSTVEKKTLTMRRNKASCSSLQAEAQAKPSGDSLPPGDNASKLPEESDGIKRQKKMKSSKKTRPKPSRKVDASFTIDMAKLFLSCVLPWGVDKELDSLCTRHLSILKLQGPVSLGLASNENLFSLMLPGWDACSTEIKEHSGINLFSRKVLELSNKYTATLPNQTGIPRGPDNHCDALQQSDTIVYLLNRLFLVNKLVNMPLDLACETDRPFKVESVHNKGKFPGSDILNISSFYGHLRNGRNEYHTPEVDISLLKLISCWRDQAVQVTEAIQAVLLAEVQQHMKHLKNTPISSQPDPVAEHTICERMLISSKVGWNEEIELPYVGNSYPPKTSVSPVKHGNDLNSANFQDTEDILDRCVLEESESAGQPRRRPWIAQVCSCRMC", "length": 1114, "header": "tr|A0A8C2LDC8-1|A0A8C2LDC8_CRIGR Isoform 1 of WD repeat-containing protein 72 isoform X1 OS=Cricetulus griseus OX=10029 GN=Wdr72 PE=4 SV=1 CANONICAL=A0A8C2LDC8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GZA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDC8/entry#A0A9J7GZA9-1", "sequence": { "sequence": "MRSALQAVALWGRKAPPHSITAIMITDDQQTIVTGSQEGQLCLWSLSPELKISAKELLFGHSASVTCLAKARDFSKQPYVVSAAENGEMYVWNVSSGQCVEKATLPYRHTAICYYHCSSRMTGDGWLLCCGEYQDVLIIDAGTLAFLHTFSSSQSPDWMKCMCIVHSVRIQEDSLLVVSVTGELKVWDLSSSINSVQEKQDVYEKESKFLDSVNCQTIRFCTYTERLLLVVFSKCWKVYDYCDFSLLWTEVSRDGQFFAGGEVLAAHRVLVWTEDGHSYIYQLLNSGLSKCICPADGGVLKETIYPHLLCSTSVEENQSLHFVMGYMNERKEPFYKVLFSGEVSGRITLWHIPDVPISKFDGSPREIPVTTTWTLQDNFDKHQTVSQSITDHFSGSRDETGMTATITSSEYIPNLDKLICGCEDGTIFITKALNAAKAGLLEGDSLLRDPPCHALLRGHHQSVTSLLYPHGLASKLDESWMVSGDQGSCVILWDIFKEEILHTFSLESGPVTRLLMSPENLKISDGQILCCVCGDHSVALLHLEGRQCLLRARKHLFPVRTIRWHPVENFLIVGCADDSVYIWEIETGTLERHETGERARIILNCGDNVQFVKSEPTLPVASETHKHKSVEQRSSNAHQPGLVPCPVLQLESSCKVADTTSVPRPFNVLPVKTKWSHIGFHVLLFDLENLVELLLPTPINDVDHSGSFYGSDILRRAKSTVEKKTLTMRRNKASCSSLQAEAQAKPSGDSLPPGDNASKLPEESDGIKRQKKMKSSKKTRPKPSRKVDASFTIDMAKLFLSCVLPWGVDKELDSLCTRHLSILKLQGPVSLGLASNENLFSLMLPGWDACSTEIKEHSGINLFSRKVLELSNKYTATLPNQTGIPRGPDNHCDALQQSDTIVYLLNRLFLVNKLVNMPLDLACETDRPFKVESVHNKGKFPGSDILNISSFYGHLRNGRNEYHTPEVDISLLKLISCWRDQAVQVTEAIQAVLLAEVQQHMKHLKNTPISSQPDPVAEHTICERMLISSKVGWNEEIELPYVGNSYPPKTSVSPVKHGNDLNSANFQDTEDILDRCVLEESESAGQPRRRPWIAQVCSCRMC", "length": 1102, "header": "tr|A0A9J7GZA9-1|A0A9J7GZA9_CRIGR Computationally mapped isoform of WD repeat-containing protein 72 isoform X2 OS=Cricetulus griseus OX=10029 GN=Wdr72 PE=4 SV=1 CANONICAL=A0A8C2LDC8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LDC8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDC8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LDC8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDC8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766058", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766058", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GHQ1-1", "protein_name": "WD repeat domain 72", "gene_name": "Wdr72", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSALQAVALWGRKAPPHSITAIMITDDQRTIVTGSQEGQLCLWSLSPELKISAKELLFGHSASVTCLARARDFSKQPYVVSAAENGEMCLWDVSSGQCVEKTTLPYRHTAICYYHCSFRMTGEGWLLCCGEYQDVLVLDAGTLAVLHTFSSSQSPDWMKCMCIVHSVRIQEDSLLVVSVTGELKVWDLSSSINSIQEKQDVYEKESKFLDSFNCQTIRFCTYTERLLLVVFSKCWKIYDYCDFSLLWTEVSRDGQFFAGGEVLAAHRILVWTEDGHSYIYQLLNRWAQMGTAFRTFSGLSKCMCPADGGVLKGTVYPHLLCSTSVEENKSLHFVMGYMNERKEPFYKVLFSGEVSGRITLWHIPDVPISKFDGSPREIPITTTWTLQDNFDKHQMVSQSIADHFSGSRDEVGETVTITSSEYVPNLDKLICGCEDGTIFITKALNAAKAGLLEGGSLLKDSPCHTLLRGHRHSVTSLLYPHSLASKLDQSWMVSGDRGSYVILWDIFTEEILHTFFLEAGPVTRLLMSPENLKRSDGQILCCVCGDHSVALLHLEGRRCLLRARKHLFPVRTIRWHPVENFLIVGCTDDSVYIWEIETGTLERHETGERARIILNCGDDAQLVRSEPTLSVASETHKHKSVEQKSSNSHLPGPVPCPGLQLESSCQVADASSVPRPFNVLPVKTKWSHVGFHVLLFDLENLVELLLPTPLSDVDPSGSFYGSDILRRAKSTVEKKTLTIRRNKASCTSLQAEAQAKSSGETLLPGDSTCKFSEESNGIKRQKKMKSSKKARPKPSRKVDASLTIDMAKLFLSCILPWGVDKELDSLCTRHLSILKLQGPVSLGLASNEDLFSLMLPGWDACNTEMKEYSGVNLCSRKVLDLSNKYTTALLNQTGIPRSLENHCDALQQSDAIVYLLSRLFLVNKLVNMPLDLACETDRPFKMESVHNKVRFPGSDILNLSSFYGHLKNGRHECHTPEADLSLLKLISCWRDQSVQVTEAIQAALLAEVQQHMKSLRDTPVRSQPDPVAEHSICERVQTSAKVEQAEELELQCVGTSSPLKTSVSSVKQGNDLNSANFQDTEDILDRCVLEESESAGQPRHRPWIAKVCSCRMC", "length": 1114 }, "evidence": [ { "id": "A0A8C2LDC8", "url": "https://omabrowser.org/oma/group/A0A8C2LDC8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0ZMD9-1", "protein_name": "WD repeat domain 72", "gene_name": "WDR72", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRVSIPAVAVWGRIAPSHSITAIMITDDQQTIVTGSQEGQICLWDLSSELKISSKEILFGHTASVTCLAKAREFEKQPYVVSATENGEMCVWNVTSGLCIENTKLPYRHTAIYYYHCSFRMTGEGWLLCFGEYQDVLIIDAKTLGVLHTLSSQSSDWINCMCIVHSARIQEDSLVAVSVTGVLKAWDLSSSLTSIQERQNVCEKESKSLGCTNCRAVRFCTYTERLLLVVSSICWQVYDYCDFSLLCTEFCKSGQCFAGGEVLAAYRLIIWTEDGYSYIYQLLNSGLSKSIYPADGKVLKETVYPHLLCFTDVKENKSFPFVMGFMNERKEPFYKILFSGEASGRITLWHVPDVPASTFDGSPQEIPISTTWTLQDNFNKAHSMAEGIIDHLCDSKDGIENAVVTSSVYIPSLDKLVCGCENGEIFITPGLETARARLLENVSLKGNLPHKVLNGHSSRVTCLLYPHGNSVRFDPSWLLSGGQDSTVICWDIFTGKILHRFSLQSGPVTELLRSPENCKLQYHSVVCCVCSDHSVAVLHLQKKVCLLHARKHLFPVKKIKFDPMEGLLIVGCEDDSVYVWEIETGTLERHETGEIAKAILSSIGDSEYLVVDSLHPVSQESKRNKNVQYKSSSSYKRGMISYNLTQTEKSSDKVMDNSLIQQPFTVLPVKPKWNNANFHVLLFDLEKLVDLLLSYQPCGLKSSNSFHNYDTLERAKSTTEKRALTLKRNKTAGFTLSVDGQVDTVYANQVNRDSNTIRPLEESGGIKRQKKMKSSRKTKMQPSGNIDVNITTDTAKLLLSCLLPWGVDKEIDDLCVGQLDILRLQCPVAFGLVSNERHLSLMLPGWKCTDGGVLEEHTLSNLFSKRVLDLSNKYLAATEGRTGERDGTVDNVYGTKGAEIIFFLLSRIVLINRVFNMPSADTSQIESLQQPESVHNKWQNMEAAISSFPSFYGELPRNKSRRHSSDFGNASLLKLICCWSDQSIKIIEAMQAVLLAEVQRTMTTLRKTAVCREPLATVENGNVSVLKHDKSSNSANFQDVEDAPDRCVLEESESPDDMKAHPWISKVCSCKVC", "length": 1073 }, "evidence": [ { "id": "A0A8C2LDC8", "url": "https://omabrowser.org/oma/group/A0A8C2LDC8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3YYM4-1", "protein_name": "WD repeat-containing protein 72", "gene_name": "Wdr72", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRGALQAVALWGRKAPPHSITAIMITDDQQTIVTGSQEGQLCLWSLSPELKISAKELLFGHSASVTCLARARDFSKQPYVVSAAENGEMCMWNVSSGQCVEKTSLPYRHTAICYYHCSFRMTGEGWLLCCGEYQDVLVLDAGTLAVLHTFTSLQSPDWMKCMCIVHSVRIQEDSLLVVSITGELKVWDLSSSINSIQEKQDVHEKESKFLDSFNCQTIRFCPYTERLLLVVFSKCWKIYDYCDFSLLWTEVSRDGQFFAGGEVLAAHRILVWTEDGHSYIYQLLNRWAQMGATLRTFSGLSKCVCPADGGVLKGTVYPHLLCSTSVEENKSLHFVMGYMNERKEPFYKVLFSGEVSGRITLWHIPDVPISKFDGSPREIPITTTWTLQDNFDKHQMVSQSITDHFSGSRDEVGMTATITSSEYIPNLDKLICGCEDGTIFITKALNAAKAGLLEGDSLLKDSPCHTLLRGHHQSVTSLLYPHNLASKLDQSWMVSGDRGSYVILWDIFTEEILHTFFLEAGPVTRLLMSPENLKRSDGQILCCVCGDHSVALLHLEGRRCLLRARKHLFPVRMIRWHPVENFLIVGCTDDSVYIWEIETGTLERHETGERARIILNCGDDAQLIRSEPTLSVASETHKHKSIEQKSSNSHQPGPVPCPSVQLESSCKVADASSVPRPFNVLPVKTKWSHIGFHVLLFDLENLVELLLPTPLSDVDPSGSFYGGDILRRAKSTVEKKTLTIRRNKASCSSLQTEAQAKPSGDSLVLGDSTSKFSEENNGIKRQKKMKSSKKAHPKPPRKVDASLTIDMAKLFLSCILPWGVDKDLDSLCTRHLSILKLQGPVSLGLASNEDLFSLMLPGWDACSTEMKEYSGVNLCSRKVLDLSSKYTATLLHQTGIPRGLESHCDSVQQSDAIVYLLSRLFLVNKLVNMPLDLACEIDRPFKMETVHSKARFPGSDILNISSFYGHPKNGGNECRAPEADLSLLKLISCWRDQSVQVTEAIQAVLLAEVQQHMKSLRNTPVSSQPDPVAEHSICERMQISAKMEWTEELELQYVGKSSPLKTSVSPVKHGNDLNSANFQDTEDILDRCVLEESESAGQPRHRPWIAKVCSCRMC", "length": 1114 }, "evidence": [ { "id": "A0A8C2LDC8", "url": "https://omabrowser.org/oma/group/A0A8C2LDC8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3MJ13-1", "protein_name": "WD repeat-containing protein 72", "gene_name": "WDR72", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRTSLQAVALWGQKAPPHSITAIMITDDQRTIVTGSQEGQLCLWNLSHELKISAKELLFGHSASVTCLARARDFSKQPYIVSAAENGEMCVWNVTNGQCMEKATLPYRHTAICYYHCSFRMTGEGWLLCCGEYQDVLIIDAKTLAVVHSFRSSQFPDWINCMCIVHSMRIQEDSLLVVSVAGELKVWDLSSSINSIQEKQDVYEKESKFLESLNCQTIRFCTYTERLLLVVFSKCWKVYDYCDFSLLLTEVSRNGQFFAGGEVIAAHRILIWTEDGHSYIYQLLNSGLSKSIYPADGRVLKETIYPHLLCSTSVQENKEQSRPFVMGYMNERKEPFYKVLFSGEVSGRITLWHIPDVPVSKFDGSPREIPVTATWTLQDNFDKHDTMSQSIIDYFSGLKDGAGTAVVTSSEYIPSLDKLICGCEDGTIIITQALNAAKARLLEGGSLVKDSPPHKVLKGHHQSVTSLLYPHGLSSKLDQSWMLSGDLDSCVILWDIFTEEILHKFFLEAGPVTSLLMSPEKFKLRGEQIICCVCGDHSVALLHLEGKSCLLHARKHLFPVRMIKWHPVENFLIVGCADDSVYIWEIETGTLERHETGERARIILNCCDDSQLVKSVLPIASETLKHKSIEQRSSSPYQLGPLPCPGLQVESSCKVTDAKFCPRPFNVLPVKTKWSNVGFHILLFDLENLVELLLPTPLSDVDSSSSFYGGEVLRRAKSTVEKKTLTLRKSKTACGPLSAEALAKPITESLAQGDNTIKFSEENDGIKRQKKMKISKKMQPKPSRKVDASLTIDTAKLFLSCLLPWGVDKDLDYLCIKHLNILKLQGPISLGISLNEDNFSLMLPGWDLCNSGMIKDYSGVNLFSRKVLDLSDKYTATLPNQVGIPRGLENNCDSLRESDTIVYLLSRLFLVNKLVNMPLELACRVGSSFRMESIHNKMRGAGNDILNMSSFYSCLRNGKNESHVPEADLSLLKLISCWRDQSVQVTEAIQAVLLAEVQQHMKSLGKIPVNSQPVSMAENGNCEMKQMLPKLEWTEELELQCVRNTLPLQTPVSPVKHDSNSNSANFQDVEDMPDRCALEESESPGEPRHHSWIAKVCPCKVS", "length": 1102 }, "evidence": [ { "id": "A0A8C2LDC8", "url": "https://omabrowser.org/oma/group/A0A8C2LDC8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LDC8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDC8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LDC8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDC8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 768, "end_pos": 770, "annotation": "n_glycosylation_sequon" }, { "start_pos": 892, "end_pos": 894, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" }, { "start_pos": 959, "end_pos": 961, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LDC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDC8" }, { "id": "PF23123", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23123" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WDR72-like alpha-solenoid", "eco_id": "ECO_0000259", "start_pos": 879, "end_pos": 1095, "start_aa": "Val", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 329, "end_pos": 331 }, { "start_pos": 768, "end_pos": 770 }, { "start_pos": 892, "end_pos": 894 }, { "start_pos": 93, "end_pos": 95 }, { "start_pos": 959, "end_pos": 961 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LDD1-1", "uniprot_ac": "A0A8C2LDD1", "uniprot_id": "A0A8C2LDD1_CRIGR", "mass": { "chemical_mass": 153337.0, "monoisotopic_mass": 153337.0 }, "refseq": { "ac": "XP_027287579", "name": "zinc finger MYM-type protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287579" }, "gene_names": [ { "name": "Zmym3", "type": "recommended", "evidence": [ { "id": "A0A8C2LDD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDD1" } ] }, { "name": "Zmym3", "type": "synonym", "evidence": [ { "id": "XP_027287579", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287579" } ] } ], "protein_names": [ { "name": "Zinc finger MYM-type protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8C2LDD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDD1/entry#names_and_taxonomy" } ] }, { "name": "zinc finger MYM-type protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027287579", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287579" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027287579", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287579" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LDD1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDD1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Zmym3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDD1", "locus": {} } ], "crossref": [ { "id": "100754045", "url": "https://www.ncbi.nlm.nih.gov/gene/100754045", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010507", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010507", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011017", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011017", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021893", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021893", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051284", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051284", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754045", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754045", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LDD1", "url": "https://www.orthodb.org/?gene=A0A8C2LDD1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45736", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45736", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45736:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45736:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06467", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06467", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12012", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12012", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027287579", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287579", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LDD1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LDD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDD1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GJP8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GJP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJP8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GJR6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GJR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJR6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JYK7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JYK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JYK7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPSDFPSPFDPLTLPEKPLAGDLPVDMEFGEDLLESQTAPTRGWAPPGPSPSSGALDLLDTPSGLEKDPGVVLDGATELLGLGGLLYKAPSPPEVDHGPEGTLAWDSGEQTLEPGPGCQTPEVMPPDPGSGASPTSPEGLLEPLAPDSPIILESPHIEEEEIPPIATRRRGSPRQEEEHTQGRPQSPNAPPSPSVGETLGDGINNSQTKPGVSIPAAHPSLPGDGLTVKESEKPPERVQKRSERVRRAEPPKPEVVDSTESIPVSDEDSDAMVDDPNDEDFVPFRPRRSPRMSLRSSMAQRAGRSSMGTKMSCAHCRTPLQKGQTAYQRKGLPQLFCSSSCLTTFSKKPLGRKTCTFCKKEIWNTKDSVVIQTGSGGSFQEFCTSVCLSLYEAQQQRPIPQSGDPADATRCSICQKTGEVLHEVSNGSVVHRLCSDSCFSKFRANKGLKTNCCDQCGAYIYARPGSLGPELLFHDGQQKRFCNTTCLGAYKKKNTRVYPCVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSYKVKQAGLTGPPRPCSFCRRSLSDPCYYNKVDRTVYQFCSPSCWTKFQRTSPEGGIHLSCHYCHSLFSGKPEVLEWQDQVFQFCCRDCCEDFKRLRGVVSQCEHCRQEKLLHEKLRFSGVEKSFCSEGCVLLYKQDFTKKLGLCCITCTYCSQTCQRGVTEQLDGSTWDFCSEDCKTKYLLWYCKAARCHACKRQGKLLETIHWRGQIRHFCNQQCLLRFYSQQNQPNLDTQSGPESLLNSQSSESKPQTPSQTKVENSITMRTPEENGNLGKIPVKIRSAPSVPTPPPPPPPATPRKNKAAMCKPLMQNRGVSCKVEMKSKGSQTEEWKPQVIVLPIPVPVFVPVPMHLYCQKVPVPFSMPIPVPVPMFLPTTLESTEKIVETIEELKVKIPSNPLEADILAMAEMIAEAEELDKASSDLCDLVSNQSAEGLLEDCDLFGTARDDVLAMAVKMANVLDEPGQDLEADFPKNPLDINPSVDFLFDCGLVGPEDVSTEQDLPRAMRKGQKRLVLSESCSRDSLSSQPSCTGLNYSYGVNAWKCWVQSKYANGESSKGDELRFGPKPMRIKEDILACSAAELNYGLAQFVREITRPNGERYEPDSIYYLCLGIQQYLLENNRMVNIFTDLYYLTFVQELNKSLSTWQPTLLPNNTVFSRVEEEHLWECKQLGVYSPFVLLNTLMFFNTKFFGLQTAEEHMQLSFTNVVRQSRKCTTPRGTTKVVSIRYYAPVRQRKGRDTGPGKRKREDETILEQRENRMNPLRCPVKFYEFYLSKCPESLRTRNDVFYLQPERSCIAESPLWYSVIPMDRSMLESMLNRILAVREIYEELGRPGEEDLD", "length": 1372, "header": "tr|A0A8C2LDD1-1|A0A8C2LDD1_CRIGR Isoform 1 of Zinc finger MYM-type protein 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Zmym3 PE=4 SV=1 CANONICAL=A0A8C2LDD1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LDD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDD1/entry#A0A8C2LDD1-1", "sequence": { "sequence": "MDPSDFPSPFDPLTLPEKPLAGDLPVDMEFGEDLLESQTAPTRGWAPPGPSPSSGALDLLDTPSGLEKDPGVVLDGATELLGLGGLLYKAPSPPEVDHGPEGTLAWDSGEQTLEPGPGCQTPEVMPPDPGSGASPTSPEGLLEPLAPDSPIILESPHIEEEEIPPIATRRRGSPRQEEEHTQGRPQSPNAPPSPSVGETLGDGINNSQTKPGVSIPAAHPSLPGDGLTVKESEKPPERVQKRSERVRRAEPPKPEVVDSTESIPVSDEDSDAMVDDPNDEDFVPFRPRRSPRMSLRSSMAQRAGRSSMGTKMSCAHCRTPLQKGQTAYQRKGLPQLFCSSSCLTTFSKKPLGRKTCTFCKKEIWNTKDSVVIQTGSGGSFQEFCTSVCLSLYEAQQQRPIPQSGDPADATRCSICQKTGEVLHEVSNGSVVHRLCSDSCFSKFRANKGLKTNCCDQCGAYIYARPGSLGPELLFHDGQQKRFCNTTCLGAYKKKNTRVYPCVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSYKVKQAGLTGPPRPCSFCRRSLSDPCYYNKVDRTVYQFCSPSCWTKFQRTSPEGGIHLSCHYCHSLFSGKPEVLEWQDQVFQFCCRDCCEDFKRLRGVVSQCEHCRQEKLLHEKLRFSGVEKSFCSEGCVLLYKQDFTKKLGLCCITCTYCSQTCQRGVTEQLDGSTWDFCSEDCKTKYLLWYCKAARCHACKRQGKLLETIHWRGQIRHFCNQQCLLRFYSQQNQPNLDTQSGPESLLNSQSSESKPQTPSQTKVENSITMRTPEENGNLGKIPVKIRSAPSVPTPPPPPPPATPRKNKAAMCKPLMQNRGVSCKVEMKSKGSQTEEWKPQVIVLPIPVPVFVPVPMHLYCQKVPVPFSMPIPVPVPMFLPTTLESTEKIVETIEELKVKIPSNPLEADILAMAEMIAEAEELDKASSDLCDLVSNQSAEGLLEDCDLFGTARDDVLAMAVKMANVLDEPGQDLEADFPKNPLDINPSVDFLFDCGLVGPEDVSTEQDLPRAMRKGQKRLVLSESCSRDSLSSQPSCTGLNYSYGVNAWKCWVQSKYANGESSKGDELRFGPKPMRIKEDILACSAAELNYGLAQFVREITRPNGERYEPDSIYYLCLGIQQYLLENNRMVNIFTDLYYLTFVQELNKSLSTWQPTLLPNNTVFSRVEEEHLWECKQLGVYSPFVLLNTLMFFNTKFFGLQTAEEHMQLSFTNVVRQSRKCTTPRGTTKVVSIRYYAPVRQRKGRDTGPGKRKREDETILEQRENRMNPLRCPVKFYEFYLSKCPESLRTRNDVFYLQPERSCIAESPLWYSVIPMDRSMLESMLNRILAVREIYEELGRPGEEDLD", "length": 1372, "header": "tr|A0A8C2LDD1-1|A0A8C2LDD1_CRIGR Isoform 1 of Zinc finger MYM-type protein 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Zmym3 PE=4 SV=1 CANONICAL=A0A8C2LDD1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GJP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDD1/entry#A0A9J7GJP8-1", "sequence": { "sequence": "MDPSDFPSPFDPLTLPEKPLAGDLPVDMEFGEDLLESQTAPTRGWAPPGPSPSSGALDLLDTPSGLEKDPGVVLDGATELLGLGGLLYKAPSPPEVDHGPEGTLAWDSGEQTLEPGPGCQTPEVMPPDPGSGASPTSPEGLLEPLAPDSPIILESPHIEEEEIPPIATRRRGSPRQEEEHTQGRPQSPNAPPSPSVGETLGDGINNSQTKPGVSIPAAHPSLPGDGLTVKESEKPPERKRSERVRRAEPPKPEVVDSTESIPVSDEDSDAMVDDPNDEDFVPFRPRRSPRMSLRSSMAQRAGRSSMGTKMSCAHCRTPLQKGQTAYQRKGLPQLFCSSSCLTTFSKKPLGRKTCTFCKKEIWNTKDSVVIQTGSGGSFQEFCTSVCLSLYEAQQQRPIPQSGDPADATRCSICQKTGEVLHEVSNGSVVHRLCSDSCFSKFRANKGLKTNCCDQCGAYIYARPGSLGPELLFHDGQQKRFCNTTCLGAYKKKNTRVYPCVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSYKVKQAGLTGPPRPCSFCRRSLSDPCYYNKVDRTVYQFCSPSCWTKFQRTSPEGGIHLSCHYCHSLFSGKPEVLEWQDQVFQFCCRDCCEDFKRLRGVVSQCEHCRQEKLLHEKLRFSGVEKSFCSEGCVLLYKQDFTKKLGLCCITCTYCSQTCQRGVTEQLDGSTWDFCSEDCKTKYLLWYCKAARCHACKRQGKLLETIHWRGQIRHFCNQQCLLRFYSQQNQPNLDTQSGPESLLNSQSSESKPQTPSQTKVENSITMRTPEENGNLGKIPVKIRSAPSVPTPPPPPPPATPRKNKAAMCKPLMQNRGVSCKVEMKSKGSQTEEWKPQVIVLPIPVPVFVPVPMHLYCQKVPVPFSMPIPVPVPMFLPTTLESTEKIVETIEELKVKIPSNPLEADILAMAEMIAEAEELDKASSDLCDLVSNQSAEGLLEDCDLFGTARDDVLAMAVKMANVLDEPGQDLEADFPKNPLDINPSVDFLFDCGLVGPEDVSTEQDLPRAMRKGQKRLVLSESCSRDSLSSQPSCTGLNYSYGVNAWKCWVQSKYANGESSKGDELRFGPKPMRIKEDILACSAAELNYGLAQFVREITRPNGERYEPDSIYYLCLGIQQYLLENNRMVNIFTDLYYLTFVQELNKSLSTWQPTLLPNNTVFSRVEEEHLWECKQLGVYSPFVLLNTLMFFNTKFFGLQTAEEHMQLSFTNVVRQSRKCTTPRGTTKVVSIRYYAPVRQRKGRDTGPGKRKREDETILEQRENRMNPLRCPVKFYEFYLSKCPESLRTRNDVFYLQPERSCIAESPLWYSVIPMDRSMLESMLNRILAVREIYEELGRPGEEDLD", "length": 1370, "header": "tr|A0A9J7GJP8-1|A0A9J7GJP8_CRIGR Computationally mapped isoform of Zinc finger MYM-type protein 3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Zmym3 PE=4 SV=1 CANONICAL=A0A8C2LDD1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GJR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDD1/entry#A0A9J7GJR6-1", "sequence": { "sequence": "MDPSDFPSPFDPLTLPEKPLAGDLPVDMEFGEDLLESQTAPTRGWAPPGDGLTVKESEKPPERKRSERVRRAEPPKPEVVDSTESIPVSDEDSDAMVDDPNDEDFVPFRPRRSPRMSLRSSMAQRAGRSSMGTKMSCAHCRTPLQKGQTAYQRKGLPQLFCSSSCLTTFSKKPLGRKTCTFCKKEIWNTKDSVVIQTGSGGSFQEFCTSVCLSLYEAQQQRPIPQSGDPADATRCSICQKTGEVLHEVSNGSVVHRLCSDSCFSKFRANKGLKTNCCDQCGAYIYARPGSLGPELLFHDGQQKRFCNTTCLGAYKKKNTRVYPCVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSYKVKQAGLTGPPRPCSFCRRSLSDPCYYNKVDRTVYQFCSPSCWTKFQRTSPEGGIHLSCHYCHSLFSGKPEVLEWQDQVFQFCCRDCCEDFKRLRGVVSQCEHCRQEKLLHEKLRFSGVEKSFCSEGCVLLYKQDFTKKLGLCCITCTYCSQTCQRGVTEQLDGSTWDFCSEDCKTKYLLWYCKAARCHACKRQGKLLETIHWRGQIRHFCNQQCLLRFYSQQNQPNLDTQSGPESLLNSQSSESKPQTPSQTKVENSITMRTPEENGNLGKIPVKIRSAPSVPTPPPPPPPATPRKNKAAMCKPLMQNRGVSCKVEMKSKGSQTEEWKPQVIVLPIPVPVFVPVPMHLYCQKVPVPFSMPIPVPVPMFLPTTLESTEKIVETIEELKVKIPSNPLEADILAMAEMIAEAEELDKASSDLCDLVSNQSAEGLLEDCDLFGTARDDVLAMAVKMANVLDEPGQDLEADFPKNPLDINPSVDFLFDCGLVGPEDVSTEQDLPRAMRKGQKRLVLSESCSRDSLSSQPSCTGLNYSYGVNAWKCWVQSKYANGESSKGDELRFGPKPMRIKEDILACSAAELNYGLAQFVREITRPNGERYEPDSIYYLCLGIQQYLLENNRMVNIFTDLYYLTFVQELNKSLSTWQPTLLPNNTVFSRVEEEHLWECKQLGVYSPFVLLNTLMFFNTKFFGLQTAEEHMQLSFTNVVRQSRKCTTPRGTTKVVSIRYYAPVRQRKGRDTGPGKRKREDETILEQRENRMNPLRCPVKFYEFYLSKCPESLRTRNDVFYLQPERSCIAESPLWYSVIPMDRSMLESMLNRILAVREIYEELGRPGEEDLD", "length": 1195, "header": "tr|A0A9J7GJR6-1|A0A9J7GJR6_CRIGR Computationally mapped isoform of Zinc finger MYM-type protein 3 isoform X4 OS=Cricetulus griseus OX=10029 GN=Zmym3 PE=4 SV=1 CANONICAL=A0A8C2LDD1-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JYK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDD1/entry#A0A9J7JYK7-1", "sequence": { "sequence": "MDPSDFPSPFDPLTLPEKPLAGDLPVDMEFGEDLLESQTAPTRGWAPPGDGLTVKESEKPPERVQKRSERVRRAEPPKPEVVDSTESIPVSDEDSDAMVDDPNDEDFVPFRPRRSPRMSLRSSMAQRAGRSSMGTKMSCAHCRTPLQKGQTAYQRKGLPQLFCSSSCLTTFSKKPLGRKTCTFCKKEIWNTKDSVVIQTGSGGSFQEFCTSVCLSLYEAQQQRPIPQSGDPADATRCSICQKTGEVLHEVSNGSVVHRLCSDSCFSKFRANKGLKTNCCDQCGAYIYARPGSLGPELLFHDGQQKRFCNTTCLGAYKKKNTRVYPCVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSYKVKQAGLTGPPRPCSFCRRSLSDPCYYNKVDRTVYQFCSPSCWTKFQRTSPEGGIHLSCHYCHSLFSGKPEVLEWQDQVFQFCCRDCCEDFKRLRGVVSQCEHCRQEKLLHEKLRFSGVEKSFCSEGCVLLYKQDFTKKLGLCCITCTYCSQTCQRGVTEQLDGSTWDFCSEDCKTKYLLWYCKAARCHACKRQGKLLETIHWRGQIRHFCNQQCLLRFYSQQNQPNLDTQSGPESLLNSQSSESKPQTPSQTKVENSITMRTPEENGNLGKIPVKIRSAPSVPTPPPPPPPATPRKNKAAMCKPLMQNRGVSCKVEMKSKGSQTEEWKPQVIVLPIPVPVFVPVPMHLYCQKVPVPFSMPIPVPVPMFLPTTLESTEKIVETIEELKVKIPSNPLEADILAMAEMIAEAEELDKASSDLCDLVSNQSAEGLLEDCDLFGTARDDVLAMAVKMANVLDEPGQDLEADFPKNPLDINPSVDFLFDCGLVGPEDVSTEQDLPRAMRKGQKRLVLSESCSRDSLSSQPSCTGLNYSYGVNAWKCWVQSKYANGESSKGDELRFGPKPMRIKEDILACSAAELNYGLAQFVREITRPNGERYEPDSIYYLCLGIQQYLLENNRMVNIFTDLYYLTFVQELNKSLSTWQPTLLPNNTVFSRVEEEHLWECKQLGVYSPFVLLNTLMFFNTKFFGLQTAEEHMQLSFTNVVRQSRKCTTPRGTTKVVSIRYYAPVRQRKGRDTGPGKRKREDETILEQRENRMNPLRCPVKFYEFYLSKCPESLRTRNDVFYLQPERSCIAESPLWYSVIPMDRSMLESMLNRILAVREIYEELGRPGEEDLD", 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"evidence": [ { "database": "UniProtKB", "id": "A0A8C2LDD1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDD1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1066, "end_pos": 1068, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1172, "end_pos": 1174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1185, "end_pos": 1187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 427, "end_pos": 429, "annotation": "n_glycosylation_sequon" }, { "start_pos": 484, "end_pos": 486, "annotation": "n_glycosylation_sequon" }, { "start_pos": 961, "end_pos": 963, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LDD1", "database": "UniProtKB", "url": 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Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615112.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003511487", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511487" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LDH3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDH3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Gpr3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDH3", "locus": {} } ], "crossref": [ { "id": "cd15963", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15963", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100759546", "url": "https://www.ncbi.nlm.nih.gov/gene/100759546", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000723", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000723", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759546", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759546", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FRTPMFL", "url": "https://omabrowser.org/oma/group/FRTPMFL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LDH3", "url": "https://www.orthodb.org/?gene=A0A8C2LDH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22750", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22750", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003511487", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003511487", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LDH3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LDH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDH3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLWGTGSSMAWLSAGSGSVNVSGVDPGEEPTGPATLLPSPKAWDVVLCISGTLVSCENALVVAIIVGTPAFRAPMFLLVGSLAIADLLAGLGLVLYFAAVFCIGSQEMSLVLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRTYLMLALVWVGALGLGLVPVLAWNCRDGLTTCGVVYPLSKNHLVVLAVAFFMVFGIMLQLYAQICRIVCRHAQQIALQRHLLPASHYVATRKGIATLAVVLGAFAACWLPFTVYCLLGDANSPYLYTYLTLLPATYNSMINPVIYAFRNQDVQKVLWAICCCCSTSKIPFRSRSPSDV", "length": 330, "header": "tr|A0A8C2LDH3-1|A0A8C2LDH3_CRIGR Isoform 1 of G-protein coupled receptor 3 OS=Cricetulus griseus OX=10029 GN=Gpr3 PE=3 SV=1 CANONICAL=A0A8C2LDH3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LDH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDH3/entry#A0A8C2LDH3-1", "sequence": { "sequence": "MLWGTGSSMAWLSAGSGSVNVSGVDPGEEPTGPATLLPSPKAWDVVLCISGTLVSCENALVVAIIVGTPAFRAPMFLLVGSLAIADLLAGLGLVLYFAAVFCIGSQEMSLVLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRTYLMLALVWVGALGLGLVPVLAWNCRDGLTTCGVVYPLSKNHLVVLAVAFFMVFGIMLQLYAQICRIVCRHAQQIALQRHLLPASHYVATRKGIATLAVVLGAFAACWLPFTVYCLLGDANSPYLYTYLTLLPATYNSMINPVIYAFRNQDVQKVLWAICCCCSTSKIPFRSRSPSDV", "length": 330, "header": "tr|A0A8C2LDH3-1|A0A8C2LDH3_CRIGR Isoform 1 of G-protein coupled receptor 3 OS=Cricetulus griseus OX=10029 GN=Gpr3 PE=3 SV=1 CANONICAL=A0A8C2LDH3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 31, "start_aa": "Thr", "end_pos": 31, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr31", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LDH3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDH3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"length": 330 }, "evidence": [ { "id": "A0A8C2LDH3", "url": "https://omabrowser.org/oma/group/A0A8C2LDH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3N0D0-1", "protein_name": "G protein-coupled receptor 3", "gene_name": "GPR3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MMWGAGSPLAWLSAGPGNVNMSSMGSTEGPTGPATPLPSPTAWDVVLCISGTLVSCENALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLGLVMHFAAVFCIGSAVMSLVLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVMLALVWGGALGLGLLPVLAWNCLDARATCGVVYPLSKNHLVVLAVAFFMVFGIMLQLYAQICRIVCRHAQQIALQRHLLPASHYVATRKGIATLAVVLGAFAACWLPFTVYCLLGDAHSPPLYTYLTLLPATYNSMINPIIYAFRNQDVQKVLWAVCCCCSSSKTLFRSRSPSDV", "length": 330 }, "evidence": [ { "id": "A0A8C2LDH3", "url": "https://omabrowser.org/oma/group/A0A8C2LDH3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P35413-1", "protein_name": "G protein-coupled receptor 3", "gene_name": "Gpr3", "tax_id": 10090, 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"https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 57, "end_pos": 297, "start_aa": "Glu", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 31 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 20, "end_pos": 22 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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LRATD1", "type": "synonym", "evidence": [ { "id": "A0A8C2LDI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDI9/entry#names_and_taxonomy" } ] }, { "name": "protein LRATD1", "type": "synonym", "evidence": [ { "id": "XP_035303257", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303257" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035303257", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303257" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LDI9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDI9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Lratd1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDI9", "locus": {} } ], "crossref": [ { "id": "100764785", "url": "https://www.ncbi.nlm.nih.gov/gene/100764785", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043299", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043299", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764785", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764785", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IYEHDDQ", "url": "https://omabrowser.org/oma/group/IYEHDDQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LDI9", "url": "https://www.orthodb.org/?gene=A0A8C2LDI9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46341", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46341", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46341:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46341:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04970", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04970", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035303257", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303257", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LDI9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LDI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDI9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGNQLDRITHLNYSELPTGDPSGIEKDELRVGVAYFFSDEEEDLDERGQPDKFGVKGPPGCSPCPESPSRHHHHLLHQLVLNETQFSAFRGQECIFSKVTGGPQGADLSVYTVTALPAICEPGDLLELLWLQPATEQPAPAPHWAVYVGGGQIIHLYQGEIRQDSLYQAGAANVGRVVNSWYRYRPLVAELVVQNACGHLGLKSEEICWTNSESFAAWCRFGKREFKAGGEVPAGTQPPQQQYYLKVHLEENKVHTARFHSLEDLIREKRRIDASGRLRVLQELEDFVDDKE", "length": 292, "header": "tr|A0A8C2LDI9-1|A0A8C2LDI9_CRIGR Isoform 1 of Protein LRATD1 OS=Cricetulus griseus OX=10029 GN=Lratd1 PE=3 SV=1 CANONICAL=A0A8C2LDI9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LDI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDI9/entry#A0A8C2LDI9-1", "sequence": { "sequence": "MGNQLDRITHLNYSELPTGDPSGIEKDELRVGVAYFFSDEEEDLDERGQPDKFGVKGPPGCSPCPESPSRHHHHLLHQLVLNETQFSAFRGQECIFSKVTGGPQGADLSVYTVTALPAICEPGDLLELLWLQPATEQPAPAPHWAVYVGGGQIIHLYQGEIRQDSLYQAGAANVGRVVNSWYRYRPLVAELVVQNACGHLGLKSEEICWTNSESFAAWCRFGKREFKAGGEVPAGTQPPQQQYYLKVHLEENKVHTARFHSLEDLIREKRRIDASGRLRVLQELEDFVDDKE", "length": 292, "header": "tr|A0A8C2LDI9-1|A0A8C2LDI9_CRIGR Isoform 1 of Protein LRATD1 OS=Cricetulus griseus OX=10029 GN=Lratd1 PE=3 SV=1 CANONICAL=A0A8C2LDI9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LDI9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDI9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LDI9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDI9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764785", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764785", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QK19-1", "protein_name": "LRAT domain containing 1", "gene_name": "LRATD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGNQLDRITHLNYSELPTGDPSGIEKDELRVGVAYFFSDEEEDLDERGQPDKFGVKGPPGCAPCPESPSRHHHHLLHQLVLNETQFSAFRGQECIFSKVSGGPQGADLSVYAVTALPALCEPGDLLELLWLQPAPEPPAPAPHWAVYVGGGQIIHLHQGEIRQDSLYEAGAANVGRVVNSWYRYRPLVAELVVQNACGHLGLKSEEICWTNSESFAAWCRFGKREFKAGGEVPAGTQPPQQQYYLKVHLGENKVHTARFHSLEDLIREKRRIDASGRLRVLQELADLVDDKE", "length": 292 }, "evidence": [ { 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This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027281707", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281707" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LDP9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDP9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ephx4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDP9", "locus": {} } ], "crossref": [ { "id": "100761937", "url": "https://www.ncbi.nlm.nih.gov/gene/100761937", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000639", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000639", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761937", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761937", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LDP9", "url": "https://www.orthodb.org/?gene=A0A8C2LDP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43329", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43329", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027281707", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281707", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LDP9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LDP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDP9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPPRPPRLVPALRALLYWSLVYGYCGLCASVHLLKLLWSIGKAPAQTFRRAARANPPACLNDPSLGTHCYVRIKDSGLRFHYVAAGERGRPLMLLLHGFPEFWYSWRHQLREFKSEYRVVALDLRGYGESDAPTHQESYKLDCLIADIKDVLDTLGYSKCVLIGHDWGGMIAWLISICYPEMIMKLVVINFPHPSVFTDYILRHPAQLLRSSFYYFFQIPWFPEFMFSINDFKALKHLFTSRSTGIGRKGRRLTTDDLEAYIYVFSQPGALSGPINHYRNIFNCLPLKHHMVTTPTLLLWGEEDAFMEAEMAEVTKTYVKNYFRLTVLSEGSHWLQQDQPDIVNRLIWAFLREERRE", "length": 358, "header": "tr|A0A8C2LDP9-1|A0A8C2LDP9_CRIGR Isoform 1 of Epoxide hydrolase 4 OS=Cricetulus griseus OX=10029 GN=Ephx4 PE=3 SV=1 CANONICAL=A0A8C2LDP9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LDP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LDP9/entry#A0A8C2LDP9-1", "sequence": { "sequence": "MAPPRPPRLVPALRALLYWSLVYGYCGLCASVHLLKLLWSIGKAPAQTFRRAARANPPACLNDPSLGTHCYVRIKDSGLRFHYVAAGERGRPLMLLLHGFPEFWYSWRHQLREFKSEYRVVALDLRGYGESDAPTHQESYKLDCLIADIKDVLDTLGYSKCVLIGHDWGGMIAWLISICYPEMIMKLVVINFPHPSVFTDYILRHPAQLLRSSFYYFFQIPWFPEFMFSINDFKALKHLFTSRSTGIGRKGRRLTTDDLEAYIYVFSQPGALSGPINHYRNIFNCLPLKHHMVTTPTLLLWGEEDAFMEAEMAEVTKTYVKNYFRLTVLSEGSHWLQQDQPDIVNRLIWAFLREERRE", "length": 358, "header": "tr|A0A8C2LDP9-1|A0A8C2LDP9_CRIGR Isoform 1 of Epoxide hydrolase 4 OS=Cricetulus griseus OX=10029 GN=Ephx4 PE=3 SV=1 CANONICAL=A0A8C2LDP9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613842.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003501352", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501352" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LE74", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE74" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tmem176a", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE74", "locus": {} } ], "crossref": [ { "id": "100764250", "url": "https://www.ncbi.nlm.nih.gov/gene/100764250", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007237", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007237", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009281", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009281", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764250", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764250", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KQGGICW", "url": "https://omabrowser.org/oma/group/KQGGICW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LE74", "url": "https://www.orthodb.org/?gene=A0A8C2LE74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15756", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15756", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15756:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15756:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04103", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04103", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003501352", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501352", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LE74", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LE74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H4Q0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4Q0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H4Q0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4Q0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMETAHVGEVALRAPQPTHIDVHIHQESALAQLLLAGCSALRLPESASTRSLGSSRLLVASWVVQIVLGLLSVVLGGMLYICHYLAMNTSGAPFWTGIVAMMAGSVAFLHKKRGGTCWALLRTLLVLMNFCMSVAAIVLGACEFNVYRYYLRDDVCVSYSSNHWPTKPPNTPGPEEADRIGLCIFYTSMLKTLLISLQAMLLGVWVLLLLASLTPVCVYFWKRCFTKMKTDEKKLLGANVI", "length": 241, "header": "tr|A0A8C2LE74-1|A0A8C2LE74_CRIGR Isoform 1 of Transmembrane protein 176A isoform X1 OS=Cricetulus griseus OX=10029 GN=Tmem176a PE=3 SV=1 CANONICAL=A0A8C2LE74-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LE74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE74/entry#A0A8C2LE74-1", "sequence": { "sequence": "MMETAHVGEVALRAPQPTHIDVHIHQESALAQLLLAGCSALRLPESASTRSLGSSRLLVASWVVQIVLGLLSVVLGGMLYICHYLAMNTSGAPFWTGIVAMMAGSVAFLHKKRGGTCWALLRTLLVLMNFCMSVAAIVLGACEFNVYRYYLRDDVCVSYSSNHWPTKPPNTPGPEEADRIGLCIFYTSMLKTLLISLQAMLLGVWVLLLLASLTPVCVYFWKRCFTKMKTDEKKLLGANVI", "length": 241, "header": "tr|A0A8C2LE74-1|A0A8C2LE74_CRIGR Isoform 1 of Transmembrane protein 176A isoform X1 OS=Cricetulus griseus OX=10029 GN=Tmem176a PE=3 SV=1 CANONICAL=A0A8C2LE74-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H4Q0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE74/entry#A0A9J7H4Q0-1", "sequence": { "sequence": "MMETAHVGEVALRAPQPTHIDVHIHQESALAQLLLAGCSALRLPESASTRSLGSSRLLVASWAMMAGSVAFLHKKRGGTCWALLRTLLVLMNFCMSVAAIVLGACEFNVYRYYLRDDVCVSYSSNHWPTKPPNTPGPEEADRIGLCIFYTSMLKTLLISLQAMLLGVWVLLLLASLTPVCVYFWKRCFTKMKTDEKKLLGANVI", "length": 204, "header": "tr|A0A9J7H4Q0-1|A0A9J7H4Q0_CRIGR Computationally mapped isoform of Transmembrane protein 176A isoform X2 OS=Cricetulus griseus OX=10029 GN=Tmem176a PE=3 SV=1 CANONICAL=A0A8C2LE74-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LE74", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE74" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LE74", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE74" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764250", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764250", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q4G068-1", "protein_name": "Transmembrane protein 176A", "gene_name": "Tmem176a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSTDMGTADVGEVDPEAPQPTNIEVHIHQESVLAKLLLAGCSFLRVPASASTQSQGSSRVLVASWVVQIVLGILSVVLGGILYICHYLAMNTQGAPFWTGIVAMLAGAVAFLQKKRGGTCWALMRILLVLASFCTAVAAIVIGSREFNNYWYYLRDDVCKSDTSYRWSTMPSITPVPEEANRIGLCKYYTSMLKTLLISLQAMLLGVWVLLLLASLIPVCVYLWKRFFTKAETEKKLLGAAVI", "length": 243 }, "evidence": [ { "id": "A0A8C2LE74", "url": "https://omabrowser.org/oma/group/A0A8C2LE74/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7YQI4-1", "protein_name": "Transmembrane protein 176A", "gene_name": "TMEM176A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "METVDCGEAAPRAPQPASIQVHFHHESGLAKLLLGGCSLLQPLLLPRPRATSRALGRHRLLATSWVMQIVLGLLSGVLGGFLYIFSSTTLRNSGAPIWTGAVAVLAGAVAFIYEKRGGIYWALLRTLLALAAFSTATAATIIGAGRFYEYHFIFYKGICNVSPSWRPTGAPTLSPDLERLQQCTAYVNMLKALFISINAMLLGVWVLLLLASLLPLCLCCWRRYRRKEKRDLPLEETVRSE", "length": 241 }, "evidence": [ { "id": "A0A8C2LE74", "url": "https://omabrowser.org/oma/group/A0A8C2LE74/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q96HP8-1", "protein_name": "Transmembrane protein 176A", "gene_name": "TMEM176A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGTADSDEMAPEAPQHTHIDVHIHQESALAKLLLTCCSALRPRATQARGSSRLLVASWVMQIVLGILSAVLGGFFYIRDYTLLVTSGAAIWTGAVAVLAGAAAFIYEKRGGTYWALLRTLLTLAAFSTAIAALKLWNEDFRYGYSYYNSACRISSSSDWNTPAPTQSPEEVRRLHLCTSFMDMLKALFRTLQAMLLGVWILLLLASLTPLWLYCWRMFPTKGKRDQKEMLEVSGI", "length": 235 }, "evidence": [ { "id": "A0A8C2LE74", "url": "https://omabrowser.org/oma/group/A0A8C2LE74/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DCS1-1", "protein_name": "Transmembrane protein 176A", "gene_name": "Tmem176a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTDMETAVVGKVDPEAPQPTHIDVHIHQESALAKLLLAGCSLLRIPASASTQSQGSSRVLVASWVVQTVLGALSVVLGGTLYIGHYLAMYSEGAPFWTGIVAMLAGAVAFLHKKRGGTCWALMRTLLVLASFCTAVAAIVIGSRELNFYWYFLGDDVCQRDSSYGWSTMPRTTPVPEEADRIALCIYYTSMLKTLLMSLQAMLLGIWVLLLLASLTPVCVYIWKRFFTKAETEEKKLLGAAVI", "length": 244 }, "evidence": [ { "id": "A0A8C2LE74", "url": "https://omabrowser.org/oma/group/A0A8C2LE74/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LE74", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE74" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LE99-1", "uniprot_ac": "A0A8C2LE99", "uniprot_id": "A0A8C2LE99_CRIGR", "mass": { "chemical_mass": 50755.0, "monoisotopic_mass": 50755.0 }, "refseq": { "ac": "XP_007651146", "name": "uncharacterized protein KIAA0930 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651146" }, "gene_names": [ { "name": "Kiaa0930", "type": "recommended", "evidence": [ { "id": "A0A8C2LE99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE99" } ] }, { "name": "Kiaa0930", "type": "synonym", "evidence": [ { "id": "XP_007651146", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651146" } ] } ], "protein_names": [ { "name": "Uncharacterized protein KIAA0930 homolog isoform X2", "type": "synonym", "evidence": [ { "id": "A0A8C2LE99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE99/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein KIAA0930 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007651146", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651146" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 205 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615466.1) and transcript sequence (IACG01055266.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007651146.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007651146", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651146" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LE99", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE99" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Kiaa0930", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE99", "locus": {} } ], "crossref": [ { "id": "100759763", "url": "https://www.ncbi.nlm.nih.gov/gene/100759763", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019141", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019141", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759763", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759763", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LE99", "url": "https://www.orthodb.org/?gene=A0A8C2LE99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21477", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21477", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21477:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21477:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09741", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09741", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007651146", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007651146", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LE99", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LE99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE99-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASARPPGRACASASAPAGLRAGPSAQPATSREPADGAEAEERSLHHMLRAIAEERGRLNLRREVCGLGCFKDDRIVFWTWMFSTYFMEKLAPRQDDMLFYVRRKRAYPGNDSSVDGRKAEAEPEVEVEVYRRDSKKLPGLGDPDIDWEESVCLNLILQKLDYMVTCAVCTRADGGDIHIHRKKSQQVFASPSKHPMDSKGEESKMSYPNIFFMIDSFEEVFSDMTVGEGEMVCVELVASDKTNTFQGVIFQGSIRYEALKKVYDNRVSVAARMAQKMSFGFYKYNNMEFVRMKGPQGKGHAEMAVSRVSTGDTSPCGTEEDSSPASPMHERVTSFSTPPTPERNNRPSFFSPSLKRKVPRNRIAEMKKSHSANDSEEFFREDDSGADLHNATNLRSRSLSGTGRSLVGSWLKLNRADGNFLLYAHLTYVTLPLHRILTDILEVRQKPILMT", "length": 452, "header": "tr|A0A8C2LE99-1|A0A8C2LE99_CRIGR Isoform 1 of Uncharacterized protein KIAA0930 homolog isoform X2 OS=Cricetulus griseus OX=10029 GN=Kiaa0930 PE=4 SV=1 CANONICAL=A0A8C2LE99-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LE99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE99/entry#A0A8C2LE99-1", "sequence": { "sequence": "MASARPPGRACASASAPAGLRAGPSAQPATSREPADGAEAEERSLHHMLRAIAEERGRLNLRREVCGLGCFKDDRIVFWTWMFSTYFMEKLAPRQDDMLFYVRRKRAYPGNDSSVDGRKAEAEPEVEVEVYRRDSKKLPGLGDPDIDWEESVCLNLILQKLDYMVTCAVCTRADGGDIHIHRKKSQQVFASPSKHPMDSKGEESKMSYPNIFFMIDSFEEVFSDMTVGEGEMVCVELVASDKTNTFQGVIFQGSIRYEALKKVYDNRVSVAARMAQKMSFGFYKYNNMEFVRMKGPQGKGHAEMAVSRVSTGDTSPCGTEEDSSPASPMHERVTSFSTPPTPERNNRPSFFSPSLKRKVPRNRIAEMKKSHSANDSEEFFREDDSGADLHNATNLRSRSLSGTGRSLVGSWLKLNRADGNFLLYAHLTYVTLPLHRILTDILEVRQKPILMT", "length": 452, "header": "tr|A0A8C2LE99-1|A0A8C2LE99_CRIGR Isoform 1 of Uncharacterized protein KIAA0930 homolog isoform X2 OS=Cricetulus griseus OX=10029 GN=Kiaa0930 PE=4 SV=1 CANONICAL=A0A8C2LE99-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 341, "start_aa": "Thr", "end_pos": 341, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr341", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LE99", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE99" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LE99", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LE99" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759763", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759763", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 374, "end_pos": 376, "annotation": "n_glycosylation_sequon" }, { "start_pos": 391, "end_pos": 393, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 341 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 111, "end_pos": 113 }, { "start_pos": 374, "end_pos": 376 }, { "start_pos": 391, "end_pos": 393 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LEG9-1", "uniprot_ac": "A0A8C2LEG9", "uniprot_id": "A0A8C2LEG9_CRIGR", "mass": { "chemical_mass": 31753.0, "monoisotopic_mass": 31753.0 }, "refseq": { "ac": "XP_003496558", "name": "enoyl-CoA hydratase domain-containing protein 2, mitochondrial isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496558" }, "gene_names": [ { "name": "Echdc2", "type": "recommended", "evidence": [ { "id": "A0A8C2LEG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEG9" } ] }, { "name": "Echdc2", "type": "synonym", "evidence": [ { "id": "XP_003496558", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496558" } ] } ], "protein_names": [ { "name": "Enoyl-CoA hydratase domain-containing protein 2, mitochondrial isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8C2LEG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEG9/entry#names_and_taxonomy" } ] }, { "name": "enoyl-CoA hydratase domain-containing protein 2, mitochondrial isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003496558", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496558" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613624.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003496558", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496558" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LEG9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEG9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Echdc2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEG9", "locus": {} } ], "crossref": [ { "id": "cd06558", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06558", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100757273", "url": "https://www.ncbi.nlm.nih.gov/gene/100757273", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018376", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018376", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757273", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757273", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WRSVAFS", "url": "https://omabrowser.org/oma/group/WRSVAFS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LEG9", "url": "https://www.orthodb.org/?gene=A0A8C2LEG9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11941", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11941", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11941:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11941:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00378", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00378", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003496558", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003496558", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LEG9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LEG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEG9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GPK3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GPK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GPK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K332", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K332", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K332-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K332-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K4J2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4J2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K4J2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K4J2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLRALPRALRLSRPWRSPGARDCASNAKTGTPEIQVHALTGPDKGITEVLMNRPHARNALGNVFVSELLEALAQLREDQQVRVLIFRSAVKGVFCAGADLKEREQMSAVEVGIFVQRLRGLMSEIAAFPAPTIAAMDGFALGGGLELALACDLRIAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRVNGMQAHELGLVNHAVAQNEEGNAAYHRALALAQEILPQAPIAVRLGKVAIDRGMEVDIASGMAIEHMCYAQNIPTQDRLEGMAAFREKRPPKFVGK", "length": 296, "header": "tr|A0A8C2LEG9-1|A0A8C2LEG9_CRIGR Isoform 1 of Enoyl-CoA hydratase domain-containing protein 2, mitochondrial isoform X1 OS=Cricetulus griseus OX=10029 GN=Echdc2 PE=3 SV=1 CANONICAL=A0A8C2LEG9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LEG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEG9/entry#A0A8C2LEG9-1", "sequence": { "sequence": "MLRALPRALRLSRPWRSPGARDCASNAKTGTPEIQVHALTGPDKGITEVLMNRPHARNALGNVFVSELLEALAQLREDQQVRVLIFRSAVKGVFCAGADLKEREQMSAVEVGIFVQRLRGLMSEIAAFPAPTIAAMDGFALGGGLELALACDLRIAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRVNGMQAHELGLVNHAVAQNEEGNAAYHRALALAQEILPQAPIAVRLGKVAIDRGMEVDIASGMAIEHMCYAQNIPTQDRLEGMAAFREKRPPKFVGK", "length": 296, "header": "tr|A0A8C2LEG9-1|A0A8C2LEG9_CRIGR Isoform 1 of Enoyl-CoA hydratase domain-containing protein 2, mitochondrial isoform X1 OS=Cricetulus griseus OX=10029 GN=Echdc2 PE=3 SV=1 CANONICAL=A0A8C2LEG9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GPK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEG9/entry#A0A9J7GPK3-1", "sequence": { "sequence": "MSAVEVGIFVQRLRGLMSEIAAFPAPTIAAMDGFALGGGLELALACDLRIAASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRVNGMQAHELGLVNHAVAQNEEGNAAYHRALALAQEILPQAPIAVRLGKVAIDRGMENIPTQDRLEGMAAFREKRPPKFVGK", "length": 175, "header": "tr|A0A9J7GPK3-1|A0A9J7GPK3_CRIGR Computationally mapped isoform of Enoyl-CoA hydratase domain-containing protein 2, mitochondrial isoform X4 OS=Cricetulus griseus OX=10029 GN=Echdc2 PE=3 SV=1 CANONICAL=A0A8C2LEG9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K332-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEG9/entry#A0A9J7K332-1", "sequence": { "sequence": "MNRPHARNALGNVFVSELLEALAQLREDQQVRVLIFRSAVKGVFCAGADLKEREQMSAVEVGIFVQRLRGLMSEIASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRVNGMQAHELGLVNHAVAQNEEGNAAYHRALALAQEILPQVDIASGMAIEHMCYAQNIPTQDRLEGMAAFREKRPPKFVGK", "length": 198, "header": "tr|A0A9J7K332-1|A0A9J7K332_CRIGR Computationally mapped isoform of Enoyl-CoA hydratase domain-containing protein 2, mitochondrial isoform X3 OS=Cricetulus griseus OX=10029 GN=Echdc2 PE=3 SV=1 CANONICAL=A0A8C2LEG9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K4J2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEG9/entry#A0A9J7K4J2-1", "sequence": { "sequence": "MNRPHARNALGNVFVSELLEALAQLREDQQVRVLIFRSAVKGVFCAGADLKEREQMSAVEVGIFVQRLRGLMSEIASSAVMGLIETTRGLLPGAGGTQRLPRCLGVALAKELIFTGRRVNGMQAHELGLVNHAVAQNEEGNAAYHRALALAQEILPQAPIAVRLGKVAIDRGMEVDIASGMAIEHMCYAQNIPTQDRLEGMAAFREKRPPKFVGK", "length": 215, "header": "tr|A0A9J7K4J2-1|A0A9J7K4J2_CRIGR Computationally mapped isoform of Enoyl-CoA hydratase domain-containing protein 2, mitochondrial isoform X2 OS=Cricetulus griseus OX=10029 GN=Echdc2 PE=3 SV=1 CANONICAL=A0A8C2LEG9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LEG9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEG9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NW_003616035.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003513658.2. 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"MRNRSVVTQFILLGIPNTEGLETMLFVLFLSFYIFTLMGNLLILLAIISSSRLHTPMYFFLCKLSIFDIFFPSVSSPKMLFYLSGNSRAISYAGCVSQLFFYHFLGCTECFLYTVMAYDRFVAICYPLRYSIIMSHRVCAILATGTSFFGCIQATFLTTLTFQLPYCGPNEVDYYFCDIPVMLKLACADTSALEMVGFISVGLMPLSCFLLILTSYSCIVCSILQIRSAEGRRRAFSTCSAHLTAILLFYMPVVLIYLRPTPSPWLDATVQVLNNLVTPMLNPLIYSLRNKEVKASLWKVLRKPAFAPEQL", "length": 311 }, "evidence": [ { "id": "A0A8C2LEJ6", "url": "https://omabrowser.org/oma/group/A0A8C2LEJ6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LEJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEJ6" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LEJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEJ6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LEJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEJ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LEJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEJ6" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 286, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 261 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 3, "end_pos": 5 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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"publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LEK3-1", "uniprot_ac": "A0A8C2LEK3", "uniprot_id": "A0A8C2LEK3_CRIGR", "mass": { "chemical_mass": 79901.0, "monoisotopic_mass": 79901.0 }, "refseq": { "ac": "XP_003514189", "name": "DNA-directed RNA polymerase III subunit RPC5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514189" }, "gene_names": [ { "name": "Polr3e", "type": "recommended", "evidence": [ { "id": "A0A8C2LEK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEK3" } ] }, { "name": "Polr3e", "type": "synonym", "evidence": [ { "id": "XP_003514189", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514189" } ] } ], "protein_names": [ { "name": "DNA-directed RNA polymerase III subunit RPC5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003514189", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514189" }, { "id": "A0A8C2LEK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEK3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616377.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003514189", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514189" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LEK3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEK3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Polr3e", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEK3", "locus": {} } ], "crossref": [ { "id": "100764912", "url": "https://www.ncbi.nlm.nih.gov/gene/100764912", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006886", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006886", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045576", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045576", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764912", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764912", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KSTCSPH", "url": "https://omabrowser.org/oma/group/KSTCSPH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LEK3", "url": "https://www.orthodb.org/?gene=A0A8C2LEK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12069", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12069", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12069:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12069:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04801", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04801", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19725", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19725", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003514189", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514189", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LEK3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LEK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FR24", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FR24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FR24-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FR24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GUQ8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GUQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GUQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GUQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJ75", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JJ75-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JJ75-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MANEEDDPVIQEIDVYLAKSLAEKLYLFQYPVRPASMTYDDIPHLSAKIKPKQQKVELEMAIDTVNPNYCRSKGEQIALNVDGACADETSTYSSKLMDKQTFCSSQTTSNTARYAAALYRQGELHLTPLHGILQLRPSFSYLDKADAKHREREAANEAGDSSQDEAEEDVKQITVRFSRPESEQARQRRVQSYEFLQKKHAEEPWVHLHYYGVKDSRSEHERQYLLCQGSSGVENTELVKSPSEYLMMLMPPSPEEEKDKPVAPSNVLSMAQLRTLPLADQIKVLMKNVKVMPFANLMSLLGPSVDSVAVLRGIQKVAMLVQGNWVVKSDILYPKDSSSPHSGMPAEVLCRGRDFVMWKFTQSRWVVRKEVAAVTKLCAEDVKDFLEHMAVVRINKGWEFLLPYDLEFIKKHPDVVQRQHMLWSGIQAKLEKVYNLVKETMPKKPDGQSGPAGLVSGEQRVQTAKTKAQQNHAFLERELQRRKEQMRAATVLPSVQIKEEPLSEEEADGEELEAEEEEPMDTAPSSCLSTKLANGLPAGRAVGGDSLNGHPIPGCASNPVAQELKAFVEATFQRQFVLTLSELKRLFNLHLAGLPPGHTLFSGISDRMLQDTVLAAGCKQILVPFPPQTAASPDEQKVFALWESGDMSDQHRQVLLEIFSKNYRVRRNMIQSRLTQECGEELSKQEVDKVLKDCCVSYGGMWYLKGTVQS", "length": 710, "header": "tr|A0A8C2LEK3-1|A0A8C2LEK3_CRIGR Isoform 1 of DNA-directed RNA polymerase III subunit RPC5 isoform X1 OS=Cricetulus griseus OX=10029 GN=Polr3e PE=4 SV=1 CANONICAL=A0A8C2LEK3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LEK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEK3/entry#A0A8C2LEK3-1", "sequence": { "sequence": "MANEEDDPVIQEIDVYLAKSLAEKLYLFQYPVRPASMTYDDIPHLSAKIKPKQQKVELEMAIDTVNPNYCRSKGEQIALNVDGACADETSTYSSKLMDKQTFCSSQTTSNTARYAAALYRQGELHLTPLHGILQLRPSFSYLDKADAKHREREAANEAGDSSQDEAEEDVKQITVRFSRPESEQARQRRVQSYEFLQKKHAEEPWVHLHYYGVKDSRSEHERQYLLCQGSSGVENTELVKSPSEYLMMLMPPSPEEEKDKPVAPSNVLSMAQLRTLPLADQIKVLMKNVKVMPFANLMSLLGPSVDSVAVLRGIQKVAMLVQGNWVVKSDILYPKDSSSPHSGMPAEVLCRGRDFVMWKFTQSRWVVRKEVAAVTKLCAEDVKDFLEHMAVVRINKGWEFLLPYDLEFIKKHPDVVQRQHMLWSGIQAKLEKVYNLVKETMPKKPDGQSGPAGLVSGEQRVQTAKTKAQQNHAFLERELQRRKEQMRAATVLPSVQIKEEPLSEEEADGEELEAEEEEPMDTAPSSCLSTKLANGLPAGRAVGGDSLNGHPIPGCASNPVAQELKAFVEATFQRQFVLTLSELKRLFNLHLAGLPPGHTLFSGISDRMLQDTVLAAGCKQILVPFPPQTAASPDEQKVFALWESGDMSDQHRQVLLEIFSKNYRVRRNMIQSRLTQECGEELSKQEVDKVLKDCCVSYGGMWYLKGTVQS", "length": 710, "header": "tr|A0A8C2LEK3-1|A0A8C2LEK3_CRIGR Isoform 1 of DNA-directed RNA polymerase III subunit RPC5 isoform X1 OS=Cricetulus griseus OX=10029 GN=Polr3e PE=4 SV=1 CANONICAL=A0A8C2LEK3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FR24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEK3/entry#A0A9J7FR24-1", "sequence": { "sequence": "MQLHSTGELHLTPLHGILQLRPSFSYLDKADAKHREREAANEAGDSSQDEAEEDVKQITVRFSRPESEQARQRRVQSYEFLQKKHAEEPWVHLHYYGVKDSRSEHERQYLLCQGSSGVENTELVKSPSEYLMMLMPPSPEEEKDKPVAPSNVLSMAQLRTLPLADQIKVLMKNVKVMPFANLMSLLGPSVDSVAVLRGIQKVAMLVQGNWVVKSDILYPKDSSSPHSGMPAEVLCRGRDFVMWKFTQSRWVVRKEVAAVTKLCAEDVKDFLEHMAVVRINKGWEFLLPYDLEFIKKHPDVVQRQHMLWSGIQAKLEKVYNLVKETMPKKPDGQSGPAGLVSGEQRVQTAKTKAQQNHAFLERELQRRKEQMRAATVLPSVQIKEEPLSEEEADGEELEAEEEEPMDTAPSSCLSTKLANGLPAGRAVGGDSLNGHPIPGCASNPVAQELKAFVEATFQRQFVLTLSELKRLFNLHLAGLPPGHTLFSGISDRMLQDTVLAAGCKQILVPFPPQTAASPDEQKVFALWESGDMSDQHRQVLLEIFSKNYRVRRNMIQSRLTQECGEELSKQEVDKVLKDCCVSYGGMWYLKGTVQS", "length": 595, "header": "tr|A0A9J7FR24-1|A0A9J7FR24_CRIGR Computationally mapped isoform of DNA-directed RNA polymerase III subunit RPC5 isoform X3 OS=Cricetulus griseus OX=10029 GN=Polr3e PE=4 SV=1 CANONICAL=A0A8C2LEK3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GUQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEK3/entry#A0A9J7GUQ8-1", "sequence": { "sequence": "MQLHSTGELHLTPLHGILQLRPSFSYLDKADAKHREREAANEGDSSQDEAEEDVKQITVRFSRPESEQARQRRVQSYEFLQKKHAEEPWVHLHYYGVKDSRSEHERQYLLCQGSSGVENTELVKSPSEYLMMLMPPSPEEEKDKPVAPSNVLSMAQLRTLPLADQIKVLMKNVKVMPFANLMSLLGPSVDSVAVLRGIQKVAMLVQGNWVVKSDILYPKDSSSPHSGMPAEVLCRGRDFVMWKFTQSRWVVRKEVAAVTKLCAEDVKDFLEHMAVVRINKGWEFLLPYDLEFIKKHPDVVQRQHMLWSGIQAKLEKVYNLVKETMPKKPDGQSGPAGLVSGEQRVQTAKTKAQQNHAFLERELQRRKEQMRAATVLPSVQIKEEPLSEEEADGEELEAEEEEPMDTAPSSCLSTKLANGLPAGRAVGGDSLNGHPIPGCASNPVAQELKAFVEATFQRQFVLTLSELKRLFNLHLAGLPPGHTLFSGISDRMLQDTVLAAGCKQILVPFPPQTAASPDEQKVFALWESGDMSDQHRQVLLEIFSKNYRVRRNMIQSRLTQECGEELSKQEVDKVLKDCCVSYGGMWYLKGTVQS", "length": 594, "header": "tr|A0A9J7GUQ8-1|A0A9J7GUQ8_CRIGR Computationally mapped isoform of DNA-directed RNA polymerase III subunit RPC5 isoform X4 OS=Cricetulus griseus OX=10029 GN=Polr3e PE=4 SV=1 CANONICAL=A0A8C2LEK3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JJ75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEK3/entry#A0A9J7JJ75-1", "sequence": { "sequence": "MANEEDDPVIQEIDVYLAKSLAEKLYLFQYPVRPASMTYDDIPHLSAKIKPKQQKVELEMAIDTVNPNYCRSKGEQIALNVDGACADETSTYSSKLMDKQTFCSSQTTSNTARYAAALYRQGELHLTPLHGILQLRPSFSYLDKADAKHREREAANEGDSSQDEAEEDVKQITVRFSRPESEQARQRRVQSYEFLQKKHAEEPWVHLHYYGVKDSRSEHERQYLLCQGSSGVENTELVKSPSEYLMMLMPPSPEEEKDKPVAPSNVLSMAQLRTLPLADQIKVLMKNVKVMPFANLMSLLGPSVDSVAVLRGIQKVAMLVQGNWVVKSDILYPKDSSSPHSGMPAEVLCRGRDFVMWKFTQSRWVVRKEVAAVTKLCAEDVKDFLEHMAVVRINKGWEFLLPYDLEFIKKHPDVVQRQHMLWSGIQAKLEKVYNLVKETMPKKPDGQSGPAGLVSGEQRVQTAKTKAQQNHAFLERELQRRKEQMRAATVLPSVQIKEEPLSEEEADGEELEAEEEEPMDTAPSSCLSTKLANGLPAGRAVGGDSLNGHPIPGCASNPVAQELKAFVEATFQRQFVLTLSELKRLFNLHLAGLPPGHTLFSGISDRMLQDTVLAAGCKQILVPFPPQTAASPDEQKVFALWESGDMSDQHRQVLLEIFSKNYRVRRNMIQSRLTQECGEELSKQEVDKVLKDCCVSYGGMWYLKGTVQS", "length": 709, "header": "tr|A0A9J7JJ75-1|A0A9J7JJ75_CRIGR Computationally mapped isoform of DNA-directed RNA polymerase III subunit RPC5 isoform X2 OS=Cricetulus griseus OX=10029 GN=Polr3e PE=4 SV=1 CANONICAL=A0A8C2LEK3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LEK3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEK3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LEK3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEK3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764912", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764912", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Z9L9-1", "protein_name": "RNA polymerase III subunit E", "gene_name": "POLR3E", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MIVPRNKPRKSFLYPSMANEEDDPIIQEIDVFLARSLLEKLYLFQYPIRPASMTYDDVTHLSAKIKPKQQKVELEMAIDTLNPNYCRSKGEQIALNVDGTCTDETSTYSSKLMDKQTFCSSQAASNVSRYAAAVYRKGELHLTPLHGILQLRPSFTYLDKADAKHREREAANEGGDSSQDEAEDDVKQITVRFSRPETEQARQRRVQSYEFLQKRQAEEHWVHLHYYGLKDSRSEHERQYLFSQGHGLAENTELIKSPSEYLMMLMPPSVEEENNKPMAPSNVLSMAQLRTLPLADQIKILMKNVKVMPFANLMSLLGSGTDSTAVLRCIQQVAMLVQGNWVVKSDVLYPKDTSSPHSGVPAEVLCRGRDFVMWKFTQDRWVVRKEVAAVTKLCPEDVKDFLEHMSVARINKGWEFMLPYDEDFVKKHPDIVQRQRMLWMGIQAKLEKVYNLVKEHLTPKKQETQSGHPLLVSGEQRVNMAKAKVKQSYGQLEKEFQKQKAELKSNDTSSKIDVSNIRIKEEPVSDEEPMDTSVYEGLNNGIANGLHAEEDSMDSLNGHLPGSCSDRVAQELKAFVSSTFKKQFVLTLSELKRLFNLHLASLPPGHILFSGISDKMLQDMVLDIGCKQILVPFPPQTAASPDELKVYALWEAGDIYDQHRQVLLEIFSKNYRVRRNVIQNQLSQDLNKQEVDRVLKDCCVSYGGMWYLKGTVQS", "length": 714 }, "evidence": [ { "id": "A0A8C2LEK3", "url": "https://omabrowser.org/oma/group/A0A8C2LEK3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZP45-1", "protein_name": "RNA polymerase III subunit E", "gene_name": "Polr3e", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANEEDDPVIQEIDVYLAKSLAEKLYLFQYPVRPASMTYDDIPHLSAKIKPKQQKVELEMAIDTLNPNYCRSKGEQIALNVDGACTDETSTYSSKLMDKQTFCSSQTTSNTARYAAALYRQGELHLTPLHGILQLRPSFSYLDKADAKHREREAANEACFTAGDSSQDEAEEDVKQITVRFSRPESEQARQRRVQSYEFLQKKHAEEPWVHLHYYGMRDSRSEHERQYLLCQGSSGVENTELVKSPSEYLMMLMPPSPEEEKDKPVAPSNVLSMAQLRTLPLADQIKVLMKNVKVMPFANLMSLLGPSVDSVAVLRGIQKVAMLVQGNWVVKSDILYPKDSSSPHSGMPAEVLCRGRDFVMWKFTQSRWVVRKEVAAVTKLCAEDVKDFLEHMAVVRINRGWEFLLPYDLEFIKKHPDVVQRQHMLWSGIQAKLEKVYNLVKETMPKKPDGPSAPVVSGEQRVQTAKTKAQQNHAFLERELQRRKEQIRGTTVLPSVQIKEEPLSEEEADGDELEAEEEEPMDTAPSSCLSTKLANGLPAGRAVGGDSLNGHPIPGCASNPVARELKAFVEATFQRQFVLTLSELKRLFNLHLAGLPPGHTLFSGVSDRMLQDTVLAAGCKQILVPFPPQTAASPDEQKVFALWESGDMSDQHRQVLLEIFSKNYRVRRNMIQSRLTQECGEELSKQEVDKVLKDCCVSCGGMWYLKGTVQS", "length": 712 }, "evidence": [ { "id": "A0A8C2LEK3", "url": "https://omabrowser.org/oma/group/A0A8C2LEK3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1R866-1", "protein_name": "DNA-directed RNA polymerase III subunit RPC5 isoform X1", "gene_name": "polr3e", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASGDDDDPIIQEIDVYLARSLVEKLYLFQYPVRPGSMSYNNVTHLGAKIKPKQQKVELEVAMDTMSPNYSRSKGEQIALNVDGMSSEDSNVYTTKMMDKQTFSSIQATTNTSRYAAAVFHKGELHLTPLQGILQMRPSFTYLDKADTKHREREAANEAGDSSQDEAEDDVKQITVRFSRPESEQARQRRIQSYEFLQKKQAEEPWVHLHYHAIKDSRSEHERQYLYCQAMDTTENTELVKTPREYLSMLMPPLAEEKVVKPVGPSNVLSMAQLRTLPLGDQVKTLMKNVKVMPFANLMGLLASGTDSTAVLRCIQQVALLVQGNWVVKSDVLYPKNTCSSHSGVPAEVLCRGRDFVMWRFTIERTLMRKEVAAIIKLPPEDVKDFLEQMSVPRLNRGWEFLLPTDQDFVKKHPDVAQRQHMLWTGIQSKLEKVFNFSKDDFVHKKDVQMEPVHLSGDQRLKAAQENAQEKHSILQRELDAHRLKASRLSGSQGPSGASVTVKQEPVSDSEEPMDTGAALTNGSVNGYPAASSPTSDPHNGHGQAFTPELQDFVKNTFRKHYVLCLSEVKRLFNLHLASLPSGHAAYGHVTDRMLQDTILHSHCKQILVPFPPQSSAAADEQKVFGLWESGETFDKLRQILFEIFMKNYRVRRNVIQTRLTQELGDAVNKTDVDRLLKECCISLGGMWYLKGTVHS", "length": 696 }, "evidence": [ { "id": "A0A8C2LEK3", "url": "https://omabrowser.org/oma/group/A0A8C2LEK3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9CZT4-1", "protein_name": "DNA-directed RNA polymerase III subunit RPC5", "gene_name": "Polr3e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANEEDDPVIQEIDVYLAKSLAEKLYLFQYPVRPASMTYDDIPHLSAKIKPKQQKVELEMAIDTLNPNYCRSKGEQIALNVDGACADETSTYSSKLMDKQTFCSSQTTSNTARYAAALYRQGELHLTPLHGILQLRPSFSYLDKADAKHREREAANEAGDSSQDEAEEDVKQITVRFSRPESEQARQRRVQSYEFLQKKHAEEPWVHLHYYGMRDSRSEHERQYLLCQGSSGVENTELVKSPSEYLMMLMPPSPEEEKDKPVAPSNVLSMAQLRTLPLADQIKVLMKNVKVMPFANLMSLLGPSVDSVAVLRGIQKVAMLVQGNWVVKSDILYPKDSSSPHSGMPAEVLCRGRDFVMWKFTQSRWVVRKEVAAVTKLCAEDVKDFLEHMAVVRINKGWEFLLPYDLEFIKKHPDVVQRQHMLWSGIQAKLEKVYNLVKETMPKKPDGQSAPVGLVSGEQRVQTAKTKAQQNHAFLERELQRRKEQMRAATVLPSVQIKEEPLSEEEADGAELEAEEEEPMDTAPSTCLSTKLANGLPAGRAVGGDSLNGHPVPGCASNPVACELKAFVEATFQRQFVLTLSELKRLFNLHLAGLPPGHILFSGVSDRMLQDTVLAAGCKQILVPFPPQTAASPDEQKVFALWESGDMSDQHRQVLLEIFSKNYRVRRNLIQSRLTQECGEELSKQEVDKVLKDCCVSCGGMWYLKGTVQS", "length": 710 }, "evidence": [ { "id": "A0A8C2LEK3", "url": "https://omabrowser.org/oma/group/A0A8C2LEK3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NVU0-1", "protein_name": "DNA-directed RNA polymerase III subunit RPC5", "gene_name": "POLR3E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MANEEDDPVVQEIDVYLAKSLAEKLYLFQYPVRPASMTYDDIPHLSAKIKPKQQKVELEMAIDTLNPNYCRSKGEQIALNVDGACADETSTYSSKLMDKQTFCSSQTTSNTSRYAAALYRQGELHLTPLHGILQLRPSFSYLDKADAKHREREAANEAGDSSQDEAEDDVKQITVRFSRPESEQARQRRVQSYEFLQKKHAEEPWVHLHYYGLRDSRSEHERQYLLCPGSSGVENTELVKSPSEYLMMLMPPSQEEEKDKPVAPSNVLSMAQLRTLPLADQIKILMKNVKVMPFANLMSLLGPSIDSVAVLRGIQKVAMLVQGNWVVKSDILYPKDSSSPHSGVPAEVLCRGRDFVMWKFTQSRWVVRKEVATVTKLCAEDVKDFLEHMAVVRINKGWEFILPYDGEFIKKHPDVVQRQHMLWTGIQAKLEKVYNLVKETMPKKPDAQSGPAGLVCGDQRIQVAKTKAQQNHALLERELQRRKEQLRVPAVPPGVRIKEEPVSEEGEEDEEQEAEEEPMDTSPSGLHSKLANGLPLGRAAGTDSFNGHPPQGCASTPVARELKAFVEATFQRQFVLTLSELKRLFNLHLASLPPGHTLFSGISDRMLQDTVLAAGCKQILVPFPPQTAASPDEQKVFALWESGDMSDQHRQVLLEIFSKNYRVRRNMIQSRLTQECGEDLSKQEVDKVLKDCCVSYGGMWYLKGTVQS", "length": 708 }, "evidence": [ { "id": "A0A8C2LEK3", "url": "https://omabrowser.org/oma/group/A0A8C2LEK3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "tRNA transcription by RNA polymerase III", "id": "GO:0042797", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042797", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LEK3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEK3" } ], "pmid": "" }, { "name": "termination of RNA polymerase III transcription", "id": "GO:0006386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006386", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LEK3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEK3" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase III promoter", "id": "GO:0006384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006384", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LEK3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEK3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LEK3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEK3" } ], "pmid": "" }, { "name": "RNA polymerase III complex", "id": "GO:0005666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005666", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LEK3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEK3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LEK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEK3" }, { "id": "PF19725", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19725" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DNA-directed RNA polymerase III subunit RPC5 C-terminal", "eco_id": "ECO_0000259", "start_pos": 443, "end_pos": 710, "start_aa": "Lys", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LEL4-1", "uniprot_ac": "A0A8C2LEL4", "uniprot_id": "A0A8C2LEL4_CRIGR", "mass": { "chemical_mass": 34094.0, "monoisotopic_mass": 34094.0 }, "refseq": { "ac": "XP_003498016", "name": "uncharacterized protein C8orf74 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498016" }, "gene_names": [ { "name": "CUNH8orf74", "type": "recommended", "evidence": [ { "id": "A0A8C2LEL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEL4" } ] }, { "name": "CUNH8orf74", "type": "synonym", "evidence": [ { "id": "XP_003498016", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498016" } ] } ], "protein_names": [ { "name": "Uncharacterized protein C8orf74 homolog", "type": "synonym", "evidence": [ { "id": "A0A8C2LEL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEL4/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C8orf74 homolog", "type": "synonym", "evidence": [ { "id": "XP_003498016", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498016" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613673.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003498016", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498016" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LEL4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEL4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "CUNH8orf74", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEL4", "locus": {} } ], "crossref": [ { "id": "100753786", "url": "https://www.ncbi.nlm.nih.gov/gene/100753786", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032727", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032727", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753786", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753786", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YQFVLCR", "url": "https://omabrowser.org/oma/group/YQFVLCR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LEL4", "url": "https://www.orthodb.org/?gene=A0A8C2LEL4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28457", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28457", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28457:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28457:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14769", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14769", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003498016", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498016", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LEL4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LEL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEL4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALLTPQGVKEVFQFQKPQGREHLRRLLNWEEFDELRDARRSILLDTVYDSIIFAVGKGFPWVEVVQVVKFTEELLKETKGCSITEAVTVLGNKLRDYQKQFNVTHLLALCDYFHNTFIRHYRLYQYVLSQEQEVNLTVAHVQMCAPPQPLPLTEGMDRDVWRHEQQMAELSTAEVQKRTNVLLLKETLSLEQAHMLQKAFGGEEAPVQLQPRPTLRREALERLVSEAIHIQIACLQELLQYEIQAAFDILDLRLQKKTLSLGAPPPPLPCITSGQVAVEESPKASKSNKGKKGKAKK", "length": 298, "header": "tr|A0A8C2LEL4-1|A0A8C2LEL4_CRIGR Isoform 1 of Uncharacterized protein C8orf74 homolog OS=Cricetulus griseus OX=10029 GN=CUNH8orf74 PE=4 SV=1 CANONICAL=A0A8C2LEL4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LEL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEL4/entry#A0A8C2LEL4-1", "sequence": { "sequence": "MALLTPQGVKEVFQFQKPQGREHLRRLLNWEEFDELRDARRSILLDTVYDSIIFAVGKGFPWVEVVQVVKFTEELLKETKGCSITEAVTVLGNKLRDYQKQFNVTHLLALCDYFHNTFIRHYRLYQYVLSQEQEVNLTVAHVQMCAPPQPLPLTEGMDRDVWRHEQQMAELSTAEVQKRTNVLLLKETLSLEQAHMLQKAFGGEEAPVQLQPRPTLRREALERLVSEAIHIQIACLQELLQYEIQAAFDILDLRLQKKTLSLGAPPPPLPCITSGQVAVEESPKASKSNKGKKGKAKK", "length": 298, "header": "tr|A0A8C2LEL4-1|A0A8C2LEL4_CRIGR Isoform 1 of Uncharacterized protein C8orf74 homolog OS=Cricetulus griseus OX=10029 GN=CUNH8orf74 PE=4 SV=1 CANONICAL=A0A8C2LEL4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LEL4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEL4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"MALLTPQGVKEVFQFQKPQGRQHLRRLLNWEEFDELRDARRSILLDTLYDSVIFAVGKGFPWVEVVQVVKFTEELLRETKGCSITEAVTILGKKLQDYQKQFNVTHLLALCDYFHNTFIRHYRLYQYVLSQDQEVNLTVAHVQMCTPPQPLPLTDGKDRDVWKHEQQVAELSAAEAEKRSDVLVLKETLRMEQAQMLQKAFGVEEAPTQLQPRPTLRREALERLVSEAIHIQIACLQELLQYEIQAAFDILDLRLQKKTLSLSAPPPPLPCITAGPAALEDSPKASKANKGKKAKAKK", "length": 298 }, "evidence": [ { "id": "A0A8C2LEL4", "url": "https://omabrowser.org/oma/group/A0A8C2LEL4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2NL11-1", "protein_name": "Uncharacterized protein C8orf74 homolog", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MALLTAQGVKKVFQFQKPEGREHLRRLLNWEEFDELRDSRRSILLDTLYESIIFAVGKGFPWREVAQVVKFTEELLKETKGCSITEAVTILGNKLRDYQGQFNTTHLLALCDYFHNTFIRHYKLYQYVLGQDQDVNLTVTNLEVCTPPQPLPLAEGKDREVWKHEQQLEELSTAEVQKRTNMLLLKGALRLEQQHLLQETFSQLPGRRHQTLNREELEKLITEAIHIQIECLKELLQYEIQITFDILDLKLQKKTLNLNAPIPPLVPIAGQPGQDEALKLSKTHKGKKAKAKK", "length": 293 }, "evidence": [ { "id": 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"MALLTPQGVKEVFQFQKPQGRQHLRRLLNWEEFDELRDARQSILLDTLYDSVIFAVGKGFPWVEVVQVVKFTEELLKETKGCSITEAVTILGKKLRDYQKQFNVTHLLALCDYSHNTFIRHYRLYQYVLSQDQEVNLTVAHEQICAPPQPLPLTDGTDRDVWRHEQQVAELSTAEVEKRANVLMLKETLRMEQAQMLQKAFGVEEAPGQLQPHPTLRKEALERLVSEAIHIQIACLQELLQYEIQAAFDILDLRLQKKTLSLSAPPPPLPCITTGPAALEDSPKASKANKGKKAKAKK", "length": 298 }, "evidence": [ { "id": "A0A8C2LEL4", "url": "https://omabrowser.org/oma/group/A0A8C2LEL4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 }, { "start_pos": 136, "end_pos": 138 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LEP1-1", "uniprot_ac": "A0A8C2LEP1", "uniprot_id": "A0A8C2LEP1_CRIGR", "mass": { "chemical_mass": 8829.0, "monoisotopic_mass": 8829.0 }, "refseq": { "ac": "XP_003498029", "name": "beta-defensin 130B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498029" }, "gene_names": [ { "name": "LOC100757854", "type": "recommended", "evidence": [ { "id": "A0A8C2LEP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEP1" } ] }, { "name": "LOC100757854", "type": "synonym", "evidence": [ { "id": "XP_003498029", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498029" } ] } ], "protein_names": [ { "name": "Beta-defensin 130B", "type": "synonym", "evidence": [ { "id": "A0A8C2LEP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEP1/entry#names_and_taxonomy" } ] }, { "name": "beta-defensin 130B", "type": "synonym", "evidence": [ { "id": "XP_003498029", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498029" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613673.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003498029", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498029" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LEP1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEP1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100757854", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEP1", "locus": {} } ], "crossref": [ { "id": "100757854", "url": "https://www.ncbi.nlm.nih.gov/gene/100757854", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757854", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757854", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TIGVCND", "url": "https://omabrowser.org/oma/group/TIGVCND/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LEP1", "url": "https://www.orthodb.org/?gene=A0A8C2LEP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20515", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20515", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20515:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20515:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00711", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00711", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003498029", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498029", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LEP1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LEP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEP1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSHSCLPVFLLLVMIMPKGKAGVVPGEKQCILLKGRCKDIACTSTDDTIGECNDEKKCCRKWWVFFPYPTPVPKGKSP", "length": 79, "header": "tr|A0A8C2LEP1-1|A0A8C2LEP1_CRIGR Isoform 1 of Beta-defensin 130B OS=Cricetulus griseus OX=10029 GN=LOC100757854 PE=4 SV=1 CANONICAL=A0A8C2LEP1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LEP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEP1/entry#A0A8C2LEP1-1", "sequence": { "sequence": "MRSHSCLPVFLLLVMIMPKGKAGVVPGEKQCILLKGRCKDIACTSTDDTIGECNDEKKCCRKWWVFFPYPTPVPKGKSP", "length": 79, "header": "tr|A0A8C2LEP1-1|A0A8C2LEP1_CRIGR Isoform 1 of Beta-defensin 130B OS=Cricetulus griseus OX=10029 GN=LOC100757854 PE=4 SV=1 CANONICAL=A0A8C2LEP1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 71, "start_aa": "Thr", "end_pos": 71, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr71", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LEP1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LEP1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"MASENQSVVTMFILQNFVDDPWLQDALFCFFFILLTMAIVGNGLIITTIHRSPSLHTPMYFFLVNLALMDVICTVTVLPKVLQSLVTENTISYGGCLTQMFIFSWVLGSELLLFSAMAYDRYLAICRPLHYGTLMNGRACVALAAFVWFTGALNSLVLTCLVLPLSFCGPNLITHFFCEIPSVLMLSCSPTFINDIMTVIADMFLTGLNFLLTMTSYGFIIASILRIRSAEGKKRAFSTCSAHLIVVTLYYSTVLYTYVRPALGTAGLLDKAIAVLYTTVTPSLNPLIYTLRNKEFKTSFKKLLFPHS", "length": 308, "header": "tr|A0A8C2LF58-1|A0A8C2LF58_CRIGR Isoform 1 of Olfactory receptor 13G1 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100763253 PE=3 SV=1 CANONICAL=A0A8C2LF58-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 281, "start_aa": "Thr", "end_pos": 281, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr281", "evidence": [ { "id": "", "database": 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"MALGNQTAVSVFILQSFTQDPWLQAALFGLFFALFVVALAGNGLITAAVCWSPTLHTPMYFFLVNLAVLDMICTSTILPKVLQGLAADSTISFWGCLSQLFFFTWSLSSELLLFSAMAYDRYLAICRPLHYGARMGGRVCVSLAAFVWGVGLLNAALLTGLVLRLSFCGPNLIAHFFCEIPPVLLLSCSPTFVNDVMTITADVFLSGMNFLLTLASYSCIVASVLRMRSAVGRRRAFSTCSSHLLVVTLYYSTVLYTYIRPGLGSAGPLDKAVAVLYTTVTPTLNPLIYTLRNKEFKAALRKLLLFSTK", "length": 309 }, "evidence": [ { "id": "A0A8C2LF58", "url": "https://omabrowser.org/oma/group/A0A8C2LF58/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8VFE8-1", "protein_name": "Olfactory receptor family 12 subfamily J member 3", "gene_name": "Or12j3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALVNQSVVTMFILQRFVDDPWIQDVLFCLFFALFMAAIAGNGLIIATIHSSPNLHTPMYFFLVNLSLMDVICTVTVLPKVLQSLVAENSISYGGCLTQMFVFSWVLGSELLLFSAMAYDRYLAICRPLHYGTLMSGKVCVALATFVWFTGALNSLVLTCLMLPLSFCGPNLITHFFCEIPSVLILSCSPTFINDIMTVITDMFLTGLNFLLTMTSYVFIIASILRIRSAEGKKRAFSTCSAHLVVVTLYYSTVLYTYVRPALGTAGFLDKLIAVLYTTVTPSLNPLIYTLRNKEFKISFKKLLFPH", "length": 307 }, "evidence": [ { "id": "A0A8C2LF58", "url": "https://omabrowser.org/oma/group/A0A8C2LF58/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LF58", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LF58" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": 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"publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LF68-1", "uniprot_ac": "A0A8C2LF68", "uniprot_id": "A0A8C2LF68_CRIGR", "mass": { "chemical_mass": 52173.0, "monoisotopic_mass": 52173.0 }, "refseq": { "ac": "XP_027253152", "name": "protein FAM124B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253152" }, "gene_names": [ { "name": "Fam124b", "type": "recommended", "evidence": [ { "id": "A0A8C2LF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LF68" } ] }, { "name": "Fam124b", "type": "synonym", "evidence": [ { "id": "XP_027253152", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253152" } ] } ], "protein_names": [ { "name": "Protein FAM124B", "type": "synonym", "evidence": [ { "id": "A0A8C2LF68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LF68/entry#names_and_taxonomy" } ] }, { "name": "protein FAM124B", "type": "synonym", "evidence": [ { "id": "XP_027253152", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253152" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027253152", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253152" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LF68", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LF68" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Fam124b", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LF68", "locus": {} } ], "crossref": [ { "id": "100759764", "url": "https://www.ncbi.nlm.nih.gov/gene/100759764", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029380", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029380", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046365", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046365", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759764", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759764", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LF68", "url": "https://www.orthodb.org/?gene=A0A8C2LF68", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14715", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14715", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14715:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14715:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027253152", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253152", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LF68", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LF68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LF68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LF68-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDETQESLALTVHLLADTGNGSLLQQALDQLLDCICPEVRLFLVSERARPVNYHEKYHPRRARFPGMSVLLFLQESLGQERLFRVLDFLQHSPWQGFPTQHAQGRPCPYLPANQEFYSLHHQMPVWGMRPVHCGTDTLRVTLYCSFDNYEDAIRLYEMILQRDATVQKSNFCFFVLYATEGFSLQLSLKQLPLGMPVDPKESSVLQFKVQEIGQLVPLLPNPCIPISSTRWQTQDYDGNKILLQVQPKSGLGVRNGECSFLNGSSKADMHRQGSRLNSVSTQRTLEPRSRRSRSRRYKAHSLELPQPCGTTENSSDPLWRSPGWCSLADSSAAGMQQYRLSIPIEPEMRMKVLKENSFQKLEAETNVDTGFTIINSKARQSFLRRFPRDFQSRQPPCRLSGSSFEVTASPSQRVFQERLCPLPLPGQRDYGVKEKNSKCSYRRPVQDEEKEEFFI", "length": 455, "header": "tr|A0A8C2LF68-1|A0A8C2LF68_CRIGR Isoform 1 of Protein FAM124B OS=Cricetulus griseus OX=10029 GN=Fam124b PE=3 SV=1 CANONICAL=A0A8C2LF68-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LF68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LF68/entry#A0A8C2LF68-1", "sequence": { "sequence": "MDETQESLALTVHLLADTGNGSLLQQALDQLLDCICPEVRLFLVSERARPVNYHEKYHPRRARFPGMSVLLFLQESLGQERLFRVLDFLQHSPWQGFPTQHAQGRPCPYLPANQEFYSLHHQMPVWGMRPVHCGTDTLRVTLYCSFDNYEDAIRLYEMILQRDATVQKSNFCFFVLYATEGFSLQLSLKQLPLGMPVDPKESSVLQFKVQEIGQLVPLLPNPCIPISSTRWQTQDYDGNKILLQVQPKSGLGVRNGECSFLNGSSKADMHRQGSRLNSVSTQRTLEPRSRRSRSRRYKAHSLELPQPCGTTENSSDPLWRSPGWCSLADSSAAGMQQYRLSIPIEPEMRMKVLKENSFQKLEAETNVDTGFTIINSKARQSFLRRFPRDFQSRQPPCRLSGSSFEVTASPSQRVFQERLCPLPLPGQRDYGVKEKNSKCSYRRPVQDEEKEEFFI", "length": 455, "header": "tr|A0A8C2LF68-1|A0A8C2LF68_CRIGR Isoform 1 of Protein FAM124B OS=Cricetulus griseus OX=10029 GN=Fam124b PE=3 SV=1 CANONICAL=A0A8C2LF68-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NW_003615540.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003512726", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512726" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LFA4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFA4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100766932", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFA4", "locus": {} } ], "crossref": [ { "id": "100766932", "url": "https://www.ncbi.nlm.nih.gov/gene/100766932", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "cge:100766932", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766932", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FLECEKM", "url": "https://omabrowser.org/oma/group/FLECEKM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LFA4", "url": "https://www.orthodb.org/?gene=A0A8C2LFA4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20515", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20515", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20515:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20515:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_003512726", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512726", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LFA4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LFA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFA4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLLFLLFLLLICLIQTASGRRRDMRFRQCEKMGGLCKYQKTHGCSILPAECKSRYKHCCRL", "length": 62, "header": "tr|A0A8C2LFA4-1|A0A8C2LFA4_CRIGR Isoform 1 of Beta-defensin 33 OS=Cricetulus griseus OX=10029 GN=LOC100766932 PE=4 SV=1 CANONICAL=A0A8C2LFA4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LFA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFA4/entry#A0A8C2LFA4-1", "sequence": { "sequence": "MKLLFLLFLLLICLIQTASGRRRDMRFRQCEKMGGLCKYQKTHGCSILPAECKSRYKHCCRL", "length": 62, "header": "tr|A0A8C2LFA4-1|A0A8C2LFA4_CRIGR Isoform 1 of Beta-defensin 33 OS=Cricetulus griseus OX=10029 GN=LOC100766932 PE=4 SV=1 CANONICAL=A0A8C2LFA4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. 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"MSRRRISCKDLGHADCQGWLYKKKEKGTFLSNKWKKFWVVLKGSSLYWYSNQMAEKADGFVNLPDFTVERASECKKKHAFKINHPQIKAFYFAAENLQEMNVWLNKLGFAVIHQESTTKDEECYSESEQEDPETASETPPPPCASATSSPVAARRASSSSPKLRDSSCSFSSLENAVKAPSPFSSSGSKERQSWNNLVNNAPVAEDVGHPLAFTVQVHTPACSEASNWQAPENSSVTSESGFLNSLSSDDTSSLSNNQDHLTVPDRASGSKMVDREEIKVSEDDEMEKLYKSLEQASLSPLGDRRPSTKKELRKSFVKRCKNPSINEKLHKIRTLNSTLKCKEHDLAMINQLLDDPKLTARKYREWKVMNTLLIQDIYHQQQVPQDPEVASQELKNPSSSDCVENSL", "length": 407, "header": "tr|A0A9J7GSZ7-1|A0A9J7GSZ7_CRIGR Computationally mapped isoform of Interactor protein for cytohesin exchange factors 1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Ipcef1 PE=4 SV=1 CANONICAL=A0A8C2LFK3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LFK3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFK3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774344", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774344", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 340, "end_pos": 342, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LFK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFK3" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 13, "end_pos": 112, "start_aa": "His", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 237, "end_pos": 239 }, { "start_pos": 340, "end_pos": 342 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027259309.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027259309", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259309" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LFK9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFK9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dpy19l4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFK9", "locus": {} } ], "crossref": [ { "id": "cd20180", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20180", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100759810", "url": "https://www.ncbi.nlm.nih.gov/gene/100759810", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018732", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018732", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047464", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047464", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759810", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759810", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LFK9", "url": "https://www.orthodb.org/?gene=A0A8C2LFK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31488", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31488", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31488:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31488:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10034", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10034", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027259309", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259309", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LFK9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LFK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFK9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FG53", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FG53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FG53-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FG53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FL21", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FL21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FL21-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FL21-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKEEGSPVELCQRKKQKTAGSQEARAEKISKTPVPERAPKYVSCQRFAKIFIGCLAAVISGMMHVFYLSAYHERKFWFSNRQELEREITFQGDSAVYYSYYKDMLKAPSFERGVYELTHNNRTVSLKTINAVQQMSLYPELIASVLYQATGSNEMIEPVYFYIGIVFGLQGIYVTALFVTSWLMSGTWLAGMLTVAWFLINRVDTTRIEYSIPLRENWALPYFACQVAALTGYLKRNLNTYAERFCYLLMSASTYTFMMAWEYSHYVLFLQAVSLLLLDVFAEEQGDKVYEVYKIYIFSLFLGYLLQFENPALLVSPLLSLVGSLMLIKCLQLNGKKGTFVAKVIKVFKFYLVCTLPLTLNLIMKTFVPHKENEHVLKFLEVKFGLNVTKNFTLNWLLCQESLQAPSQDFFLRLTQSSLLPFYILVLIICLLSMTQVIFRRINGKSQKETVTLEDGRIGERPEIIYHVIHTLILGSLSMLMEGLKFIWTPYVCMLAAFGVCSPELWMTLLKWLRLRTVHPILLALILSMAVPTIIGLSLWKEFFPRLITELTELQEFYDPDTVELMTWIKRQAPVAAVFAGSPQLMGVIKLCTGWMVTSLPLYSDDDLLRRNENIYQIYSKRSAEDIYKILTSYKANYLIVEDAICNEMGTTRGCRVKDLLDVANGHVVCDEGDKLTYSKYGRFCHEVKINYSPYVNYFTRVYWNRSYFVYKVNTVISFQS", "length": 722, "header": "tr|A0A8C2LFK9-1|A0A8C2LFK9_CRIGR Isoform 1 of Probable C-mannosyltransferase DPY19L4 isoform X2 OS=Cricetulus griseus OX=10029 GN=Dpy19l4 PE=3 SV=1 CANONICAL=A0A8C2LFK9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LFK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFK9/entry#A0A8C2LFK9-1", "sequence": { "sequence": "MAKEEGSPVELCQRKKQKTAGSQEARAEKISKTPVPERAPKYVSCQRFAKIFIGCLAAVISGMMHVFYLSAYHERKFWFSNRQELEREITFQGDSAVYYSYYKDMLKAPSFERGVYELTHNNRTVSLKTINAVQQMSLYPELIASVLYQATGSNEMIEPVYFYIGIVFGLQGIYVTALFVTSWLMSGTWLAGMLTVAWFLINRVDTTRIEYSIPLRENWALPYFACQVAALTGYLKRNLNTYAERFCYLLMSASTYTFMMAWEYSHYVLFLQAVSLLLLDVFAEEQGDKVYEVYKIYIFSLFLGYLLQFENPALLVSPLLSLVGSLMLIKCLQLNGKKGTFVAKVIKVFKFYLVCTLPLTLNLIMKTFVPHKENEHVLKFLEVKFGLNVTKNFTLNWLLCQESLQAPSQDFFLRLTQSSLLPFYILVLIICLLSMTQVIFRRINGKSQKETVTLEDGRIGERPEIIYHVIHTLILGSLSMLMEGLKFIWTPYVCMLAAFGVCSPELWMTLLKWLRLRTVHPILLALILSMAVPTIIGLSLWKEFFPRLITELTELQEFYDPDTVELMTWIKRQAPVAAVFAGSPQLMGVIKLCTGWMVTSLPLYSDDDLLRRNENIYQIYSKRSAEDIYKILTSYKANYLIVEDAICNEMGTTRGCRVKDLLDVANGHVVCDEGDKLTYSKYGRFCHEVKINYSPYVNYFTRVYWNRSYFVYKVNTVISFQS", "length": 722, "header": "tr|A0A8C2LFK9-1|A0A8C2LFK9_CRIGR Isoform 1 of Probable C-mannosyltransferase DPY19L4 isoform X2 OS=Cricetulus griseus OX=10029 GN=Dpy19l4 PE=3 SV=1 CANONICAL=A0A8C2LFK9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FG53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFK9/entry#A0A9J7FG53-1", "sequence": { "sequence": "MMHVFYLSAYHERKFWFSNRQELEREITFQGDSAVYYSYYKDMLKAPSFERGVYELTHNNRTVSLKTINAVQQMSLYPELIASVLYQATGSNEMIEPVYFYIGIVFGLQGIYVTALFVTSWLMSGTWLAGMLTVAWFLINRVDTTRIEYSIPLRENWALPYFACQVAALTGYLKRNLNTYAERFCYLLMSASTYTFMMAWEYSHYVLFLQAVSLLLLDVFAEEQGDKVYEVYKIYIFSLFLGYLLQFENPALLVSPLLSLVGSLMLIKCLQLNGKKGTFVAKVIKVFKFYLVCTLPLTLNLIMKTFVPHKENEHVLKFLEVKFGLNVTKNFTLNWLLCQESLQAPSQDFFLRLTQSSLLPFYILVLIICLLSMTQVIFRRINGKSQKETVTLEDGRIGERPEIIYHVIHTLILGSLSMLMEGLKFIWTPYVCMLAAFGVCSPELWMTLLKWLRLRTVHPILLALILSMAVPTIIGLSLWKEFFPRLITELTELQEFYDPDTVELMTWIKRQAPVAAVFAGSPQLMGVIKLCTGWMVTSLPLYSDDDLLRRNENIYQIYSKRSAEDIYKILTSYKANYLIVEDAICNEMGTTRGCRVKDLLDVANGHVVCDEGDKLTYSKYGRFCHEVKINYSPYVNYFTRVYWNRSYFVYKVNTVISFQS", "length": 660, "header": "tr|A0A9J7FG53-1|A0A9J7FG53_CRIGR Computationally mapped isoform of Probable C-mannosyltransferase DPY19L4 isoform X4 OS=Cricetulus griseus OX=10029 GN=Dpy19l4 PE=3 SV=1 CANONICAL=A0A8C2LFK9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FL21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFK9/entry#A0A9J7FL21-1", "sequence": { "sequence": "MAKEEGSPVELCQRKKQKTAGSQEARAEKISKTPVPERAPKYVSCQRFAKIFIGCLAAVISGMMHVFYLSAYHERKFWFSNRQELEREITFQGDSAVYYSYYKDMLKAPSFERGVYELTHNNRTVSLKTINAVQQMSLYPELIASVLYQATGSNEMIEPVYFYIGIVFGLQGIYVTALFVTSWLMSGTWLAGMLTVAWFLINRVDTTRIEYSIPLRENWALPYFACQVAALTGYLKRNLNTYAERFCYLLMSASTYTFMMAWEYSHYVLFLQAVSLLLLDVFAEEQGDKVYEVYKIYIFSLFLGYLLQFENPALLVSPLLSLVGSLMLIKCLQLNGKKGTFVAKVIKVFKFYLVCTLPLTLNLIMKTFVPHKENEHVLKFLEVKFGLNVTKNFTLNWLLCQESLQAPSQDFFLRLTQSSLLPFYILVLIICLLSMTQVIFRRINGKSQKETVTLEDGRIGERPEIIYHVIHTLILGSLSMLMEGLKFIWTPYVCMLAAFGVCSPELWMTLLKWLRLRTVHPILLALILSMAVPTIIGLSLWKEFFPRLITELTELQEFYDPDTVELMTWIKRQAPVAAVFAGSPQLMGVIKLCTGWMVTSLPLYSDDDLLRRNENIYQIYSKRSAEDIYKILTSYKANYLIVEDAICNEMGTTRGCRVKDLLDVANGHFPSFSTGETAQHLRAPLALEEDPGSVSELT", "length": 698, "header": "tr|A0A9J7FL21-1|A0A9J7FL21_CRIGR Computationally mapped isoform of Probable C-mannosyltransferase DPY19L4 isoform X3 OS=Cricetulus griseus OX=10029 GN=Dpy19l4 PE=3 SV=1 CANONICAL=A0A8C2LFK9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LFK9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFK9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LFK9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFK9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759810", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759810", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "mannosyltransferase activity", "id": "GO:0000030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000030", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LFK9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFK9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nuclear inner membrane", "id": "GO:0005637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005637", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LFK9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFK9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 388, "end_pos": 390, "annotation": "n_glycosylation_sequon" }, { "start_pos": 392, "end_pos": 394, "annotation": "n_glycosylation_sequon" }, { "start_pos": 692, "end_pos": 694, "annotation": "n_glycosylation_sequon" }, { "start_pos": 706, "end_pos": 708, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 122, "end_pos": 124 }, { "start_pos": 388, "end_pos": 390 }, { "start_pos": 392, "end_pos": 394 }, { "start_pos": 692, "end_pos": 694 }, { "start_pos": 706, "end_pos": 708 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LFM9-1", "uniprot_ac": "A0A8C2LFM9", "uniprot_id": "A0A8C2LFM9_CRIGR", "mass": { "chemical_mass": 13775.0, "monoisotopic_mass": 13775.0 }, "refseq": { "ac": "XP_027283995", "name": "keratin-associated protein 2-1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283995" }, "gene_names": [ { "name": "LOC100756520", "type": "recommended", "evidence": [ { "id": "A0A8C2LFM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFM9" } ] }, { "name": "LOC100756520", "type": "synonym", "evidence": [ { "id": "XP_027283995", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283995" } ] } ], "protein_names": [ { "name": "Keratin-associated protein 2-1 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A8C2LFM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFM9/entry#names_and_taxonomy" } ] }, { "name": "keratin-associated protein 2-1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027283995", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283995" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027283995", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283995" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LFM9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFM9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100756520", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFM9", "locus": {} } ], "crossref": [ { "id": "100756520", "url": "https://www.ncbi.nlm.nih.gov/gene/100756520", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756520", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756520", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LFM9", "url": "https://www.orthodb.org/?gene=A0A8C2LFM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48425", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48425", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48425:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48425:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01500", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01500", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027283995", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283995", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LFM9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LFM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFM9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTGSCCGSFSSQSCGGCCQPCCCRDPCCCRPVSCQTTVCRPVTCVPHCTRPICEPCRRPICCDPCSLQQGCCRPITCCPTSCTAVVCRPCCWASTCCQPISVQAPCCRPPCCQPAPCRTTCRTSPCNACC", "length": 130, "header": "tr|A0A8C2LFM9-1|A0A8C2LFM9_CRIGR Isoform 1 of Keratin-associated protein 2-1 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100756520 PE=4 SV=1 CANONICAL=A0A8C2LFM9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LFM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFM9/entry#A0A8C2LFM9-1", "sequence": { "sequence": "MTGSCCGSFSSQSCGGCCQPCCCRDPCCCRPVSCQTTVCRPVTCVPHCTRPICEPCRRPICCDPCSLQQGCCRPITCCPTSCTAVVCRPCCWASTCCQPISVQAPCCRPPCCQPAPCRTTCRTSPCNACC", "length": 130, "header": "tr|A0A8C2LFM9-1|A0A8C2LFM9_CRIGR Isoform 1 of Keratin-associated protein 2-1 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100756520 PE=4 SV=1 CANONICAL=A0A8C2LFM9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"MAVDTLSPDWEFDRVDDGSQKIHAEVQLKNYGKFLEEYTSQLRRIEDALDDLIGDVWDFNLDPIALKLLPYEQSSLLELIKTENKVLNKVITVYAALCCEIKKLKYEAETKFYNGLLFYGEGATDSSMVEGDCQIQMGRFVSFLQELSCFVTRCYEVVMNVIHQLAALYISNKIGPKIIETTGVHFQTMYEHLGELLTVLLTLDEIIDNHVTLKDHWTMYKRLLKSVHHNPSKFGIQEEKLKPFEKFLLKLEGQLFDGMIFQACIEQQFDSLNGGISVSKNSTFAEEFAHSIRSIFANVEAKLGEPSEIDQRDKYVGICGLFVLHFQIFRTVDKKFYKSLLDICKKVPAITLTANIIWFPDNFLIHKMPAAAKLVDRKSLQAIKIHRDTFLQQKAQSLTKDVQSYYVFVSSWMMKMESMLSKEQRMDKFAEDLTNRCNVFIQGFLYAYSISTIIKTTMNLYMSMQKPMTKTSVKALCRLIELLKAIEHMFYRRSMVVADSVSHITQHLQHQALNSISVAKKRVISDKKYSEQRLDVLSALVLAENTLNGPSTKQRRLIVSLALSVGTQMKTFKDEELFPLQVVMKKLDLISELRERVQTQCDCCFLYWHRAVFPIYLDDVYENAVDAARLHYMFSALRDCVPAMMHSRHLESYELLLDCYDKEIMEILNEHLLDKLCKEIEKDLRLSVHTHLKLDDRNPFRVGRKDLALFFSLNPIRFFSRFIDIRAYVTHYLDKTFYNLTTVALHDWATYSEMRNLATQRYGLVMTEAHLPSQTLEQGLDVLEIMRNIHIFVSRYLYNLNNQIFIERTSNNKHLNTINIRHIANSIRTHGTGIMNTTVNFTYQFLKKKFYIFSQFMYDEHIKSRLIKDIRFFREIKDQNDHKYPFDRAEKFNRGIRKLGITPEGQSYLDQFRQLISQIGNAMGYIRMIRSGGLHCSSNAIRFVPDLEDIVSFEELVKEEGLAEETLRAARHLDSVLSDHTRNSAEGTEYFKMLVDVFAPEFRRPKNIHLRNFYIIVPPLTLNFVEHSISCKEKLNKKNKIGAAFTDDGFAMGVAYTLKLLDQYQEFDSLHWFQSVREKYIKEIRAVAKQQNVQSTSQDEKLLQTMNLTQKRLEVYLQEFELLYFSLSSARIFFRADKTAAEENQEKKEKEEETKTSSGDVPEGSVSTDPVVK", "length": 1173, "header": "tr|A0A8C2LFS9-1|A0A8C2LFS9_CRIGR Isoform 1 of WASH complex subunit 4 isoform X1 OS=Cricetulus griseus OX=10029 GN=Washc4 PE=4 SV=1 CANONICAL=A0A8C2LFS9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LFS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFS9/entry#A0A8C2LFS9-1", "sequence": { "sequence": "MAVDTLSPDWEFDRVDDGSQKIHAEVQLKNYGKFLEEYTSQLRRIEDALDDLIGDVWDFNLDPIALKLLPYEQSSLLELIKTENKVLNKVITVYAALCCEIKKLKYEAETKFYNGLLFYGEGATDSSMVEGDCQIQMGRFVSFLQELSCFVTRCYEVVMNVIHQLAALYISNKIGPKIIETTGVHFQTMYEHLGELLTVLLTLDEIIDNHVTLKDHWTMYKRLLKSVHHNPSKFGIQEEKLKPFEKFLLKLEGQLFDGMIFQACIEQQFDSLNGGISVSKNSTFAEEFAHSIRSIFANVEAKLGEPSEIDQRDKYVGICGLFVLHFQIFRTVDKKFYKSLLDICKKVPAITLTANIIWFPDNFLIHKMPAAAKLVDRKSLQAIKIHRDTFLQQKAQSLTKDVQSYYVFVSSWMMKMESMLSKEQRMDKFAEDLTNRCNVFIQGFLYAYSISTIIKTTMNLYMSMQKPMTKTSVKALCRLIELLKAIEHMFYRRSMVVADSVSHITQHLQHQALNSISVAKKRVISDKKYSEQRLDVLSALVLAENTLNGPSTKQRRLIVSLALSVGTQMKTFKDEELFPLQVVMKKLDLISELRERVQTQCDCCFLYWHRAVFPIYLDDVYENAVDAARLHYMFSALRDCVPAMMHSRHLESYELLLDCYDKEIMEILNEHLLDKLCKEIEKDLRLSVHTHLKLDDRNPFRVGRKDLALFFSLNPIRFFSRFIDIRAYVTHYLDKTFYNLTTVALHDWATYSEMRNLATQRYGLVMTEAHLPSQTLEQGLDVLEIMRNIHIFVSRYLYNLNNQIFIERTSNNKHLNTINIRHIANSIRTHGTGIMNTTVNFTYQFLKKKFYIFSQFMYDEHIKSRLIKDIRFFREIKDQNDHKYPFDRAEKFNRGIRKLGITPEGQSYLDQFRQLISQIGNAMGYIRMIRSGGLHCSSNAIRFVPDLEDIVSFEELVKEEGLAEETLRAARHLDSVLSDHTRNSAEGTEYFKMLVDVFAPEFRRPKNIHLRNFYIIVPPLTLNFVEHSISCKEKLNKKNKIGAAFTDDGFAMGVAYTLKLLDQYQEFDSLHWFQSVREKYIKEIRAVAKQQNVQSTSQDEKLLQTMNLTQKRLEVYLQEFELLYFSLSSARIFFRADKTAAEENQEKKEKEEETKTSSGDVPEGSVSTDPVVK", "length": 1173, "header": "tr|A0A8C2LFS9-1|A0A8C2LFS9_CRIGR Isoform 1 of WASH complex subunit 4 isoform X1 OS=Cricetulus griseus OX=10029 GN=Washc4 PE=4 SV=1 CANONICAL=A0A8C2LFS9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F4V4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFS9/entry#A0A9J7F4V4-1", "sequence": { "sequence": "MYEHLGELLTVLLTLDEIIDNHVTLKDHWTMYKRLLKSVHHNPSKFGIQEEKLKPFEKFLLKLEGQLFDGMIFQACIEQQFDSLNGGISVSKNSTFAEEFAHSIRSIFANVEAKLGEPSEIDQRDKYVGICGLFVLHFQIFRTVDKKFYKSLLDICKKVPAITLTANIIWFPDNFLIHKMPAAAKLVDRKSLQAIKIHRDTFLQQKAQSLTKDVQSYYVFVSSWMMKMESMLSKEQRMDKFAEDLTNRCNVFIQGFLYAYSISTIIKTTMNLYMSMQKPMTKTSVKALCRLIELLKAIEHMFYRRSMVVADSVSHITQHLQHQALNSISVAKKRVISDKKYSEQRLDVLSALVLAENTLNGPSTKQRRLIVSLALSVGTQMKTFKDEELFPLQVVMKKLDLISELRERVQTQCDCCFLYWHRAVFPIYLDDVYENAVDAARLHYMFSALRDCVPAMMHSRHLESYELLLDCYDKEIMEILNEHLLDKLCKEIEKDLRLSVHTHLKLDDRNPFRVGRKDLALFFSLNPIRFFSRFIDIRAYVTHYLDKTFYNLTTVALHDWATYSEMRNLATQRYGLVMTEAHLPSQTLEQGLDVLEIMRNIHIFVSRYLYNLNNQIFIERTSNNKHLNTINIRHIANSIRTHGTGIMNTTVNFTYQFLKKKFYIFSQFMYDEHIKSRLIKDIRFFREIKDQNDHKYPFDRAEKFNRGIRKLGITPEGQSYLDQFRQLISQIGNAMGYIRMIRSGGLHCSSNAIRFVPDLEDIVSFEELVKEEGLAEETLRAARHLDSVLSDHTRNSAEGTEYFKMLVDVFAPEFRRPKNIHLRNFYIIVPPLTLNFVEHSISCKEKLNKKNKIGAAFTDDGFAMGVAYTLKLLDQYQEFDSLHWFQSVREKYIKEIRAVAKQQNVQSTSQDEKLLQTMNLTQKRLEVYLQEFELLYFSLSSARIFFRADKTAAEENQEKKEKEEETKTSSGDVPEGSVSTDPVVK", "length": 985, "header": "tr|A0A9J7F4V4-1|A0A9J7F4V4_CRIGR Computationally mapped isoform of WASH complex subunit 4 isoform X3 OS=Cricetulus griseus OX=10029 GN=Washc4 PE=4 SV=1 CANONICAL=A0A8C2LFS9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J7C8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFS9/entry#A0A9J7J7C8-1", "sequence": { "sequence": "MAVDTLSPDWEFDRVDDGSQKIHAEVQLKNYGKFLEEYTSQLRRIEDALDDLIGDVWDFNLDPIALKLLPYEQSSLLELIKTENKVLNKVITVYAALCCEIKKLKYEAETKFYNGLLFYGEGATDSSMVEGDCQIQMGRFVSFLQELSCFVTRCYEVVMNVIHQLAALYISNKIGPKIIETTGVHFQTMYEHLGELLTVLLTLDEIIDNHVTLKDHWTMYKRLLKSVHHNPSKFGIQEEKLKPFEKFLLKLEGQLFDGMIFQACIEQQFDSLNGGISVSKNSTFAEEFAHSIRSIFANVEAKLGEPSEIDQRDKYVGICGLFVLHFQIFRTVDKKFYKSLLDICKKVPAITLTANIIWFPDNFLIHKMPAAAKLVDRKSLQAIKIHRDTFLQQKAQSLTKDVQSYYVFVSSWMMKMESMLSKEQRMDKFAEDLTNRCNVFIQGFLYAYSISTIIKTTMNLYMSMQKPMTKTSVKALCRLIELLKKRVISDKKYSEQRLDVLSALVLAENTLNGPSTKQRRLIVSLALSVGTQMKTFKDEELFPLQVVMKKLDLISELRERVQTQCDCCFLYWHRAVFPIYLDDVYENAVDAARLHYMFSALRDCVPAMMHSRHLESYELLLDCYDKEIMEILNEHLLDKLCKEIEKDLRLSVHTHLKLDDRNPFRVGRKDLALFFSLNPIRFFSRFIDIRAYVTHYLDKTFYNLTTVALHDWATYSEMRNLATQRYGLVMTEAHLPSQTLEQGLDVLEIMRNIHIFVSRYLYNLNNQIFIERTSNNKHLNTINIRHIANSIRTHGTGIMNTTVNFTYQFLKKKFYIFSQFMYDEHIKSRLIKDIRFFREIKDQNDHKYPFDRAEKFNRGIRKLGITPEGQSYLDQFRQLISQIGNAMGYIRMIRSGGLHCSSNAIRFVPDLEDIVSFEELVKEEGLAEETLRAARHLDSVLSDHTRNSAEGTEYFKMLVDVFAPEFRRPKNIHLRNFYIIVPPLTLNFVEHSISCKEKLNKKNKIGAAFTDDGFAMGVAYTLKLLDQYQEFDSLHWFQSVREKYIKEIRAVAKQQNVQSTSQDEKLLQTMNLTQKRLEVYLQEFELLYFSLSSARIFFRADKTAAEENQEKKEKEEETKTSSGDVPEGSVSTDPVVK", "length": 1137, "header": "tr|A0A9J7J7C8-1|A0A9J7J7C8_CRIGR Computationally mapped isoform of WASH complex subunit 4 isoform X2 OS=Cricetulus griseus OX=10029 GN=Washc4 PE=4 SV=1 CANONICAL=A0A8C2LFS9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LFS9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFS9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LFS9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFS9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100772083", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772083", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LFS9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFS9" } ], "pmid": "" }, { "name": "WASH complex", "id": "GO:0071203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071203", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LFS9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFS9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "endosome organization", "id": "GO:0007032", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007032", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LFS9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFS9" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LFS9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFS9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1107, "end_pos": 1109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 281, "end_pos": 283, "annotation": "n_glycosylation_sequon" }, { "start_pos": 739, "end_pos": 741, "annotation": "n_glycosylation_sequon" }, { "start_pos": 836, "end_pos": 838, "annotation": "n_glycosylation_sequon" }, { "start_pos": 840, "end_pos": 842, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LFS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFS9" }, { "id": "PF14745", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14745" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WASH complex subunit 4 N-terminal", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 603, "start_aa": "Gly", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2LFS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFS9" }, { "id": "PF14746", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14746" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WASH complex subunit 7 C-terminal", "eco_id": "ECO_0000259", "start_pos": 966, "end_pos": 1135, "start_aa": "Thr", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2LFS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFS9" }, { "id": "PF14744", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14744" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WASH complex subunit 7 central", "eco_id": "ECO_0000259", "start_pos": 605, "end_pos": 948, "start_aa": "Phe", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1107, "end_pos": 1109 }, { "start_pos": 281, "end_pos": 283 }, { "start_pos": 739, "end_pos": 741 }, { "start_pos": 836, "end_pos": 838 }, { "start_pos": 840, "end_pos": 842 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LFU9-1", "uniprot_ac": "A0A8C2LFU9", "uniprot_id": "A0A8C2LFU9_CRIGR", "mass": { "chemical_mass": 15720.0, "monoisotopic_mass": 15720.0 }, "refseq": { "ac": "XP_027252263", "name": "testis-expressed protein 49 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027252263" }, "gene_names": [ { "name": "Tex49", "type": "recommended", "evidence": [ { "id": "A0A8C2LFU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LFU9" } ] }, { "name": "Tex49", "type": "synonym", "evidence": [ { "id": "XP_027252263", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027252263" } ] } ], "protein_names": [ { "name": "Testis-expressed protein 49 isoform X2", "type": 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This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. 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"MARGGLGAEEASLRSNALSWLACGLLALLANAWIILSISAKQQKHKPLELLLCFLAGTHILMAAVPLTTFAVVQLRRQASSDYDWNESICKVFVSTYYTLALATCFTVASLSYHRMWMVRWPVNYRLSNAKKQALHAVVGIWMVSFILSTLPSIGWHNNGERYYARGCQFIVSKIGLGFGVCFSLLLLGGIVMGLVCVAITFYQTLWARPRRAQQARKAGGSVGAKVGGLGGLGTRPAFEVPAIVVEDTRGKRRSSLDGSESAKTSLQVTNLVSAIVFLYDSLTGVPILVVSFFSLKSDSAPPWMVLAVLWCSMAQTLLLPSFIWSCERYRADVRTVWEQCVAIMSEDDGDDDGACDDYTDGRVCKIRFDANGATGSGGRDPTQVKLLPGRHMLFPPLERVHYLQVPLSRRLSHDETNIFSTPRAPGSFLHKWSSSDDIRVLPAQSRALGGPPEYLGQRHRLGDEEDEEEAEGGGLASLRQFLESGVLGSGGGPPRGPGFFREEITTFIDETPLPSPTASPGPSPRRPRPLGFSPRRLSLGSPDSRPVGLPLGLSAGRRCSLTGSEGSSRAWGRPWGPGNPIFSQLTL", "length": 588, "header": "tr|A0A8C2LGC7-1|A0A8C2LGC7_CRIGR Isoform 1 of Probable G-protein coupled receptor 162 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100768504 PE=4 SV=1 CANONICAL=A0A8C2LGC7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LGC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGC7/entry#A0A8C2LGC7-1", "sequence": { "sequence": 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"enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 518 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 86, "end_pos": 88 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { 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"A0A8C2LGD6_CRIGR", "mass": { "chemical_mass": 46316.0, "monoisotopic_mass": 46316.0 }, "refseq": { "ac": "XP_035294864", "name": "acyl-coenzyme A amino acid N-acyltransferase 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294864" }, "gene_names": [ { "name": "LOC100756541", "type": "recommended", "evidence": [ { "id": "A0A8C2LGD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGD6" } ] }, { "name": "LOC100756541", "type": "synonym", "evidence": [ { "id": "XP_035294864", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294864" } ] } ], "protein_names": [ { "name": "Acyl-coenzyme A amino acid N-acyltransferase 2", "type": "synonym", "evidence": [ { "id": "A0A8C2LGD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGD6/entry#names_and_taxonomy" } ] }, { "name": "acyl-coenzyme A amino acid N-acyltransferase 2", "type": "synonym", "evidence": [ { "id": "XP_035294864", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294864" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035294864", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294864" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LGD6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGD6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100756541", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGD6", "locus": {} } ], "crossref": [ { "id": "100756541", "url": "https://www.ncbi.nlm.nih.gov/gene/100756541", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006862", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006862", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016662", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016662", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042490", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042490", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756541", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756541", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LGD6", "url": "https://www.orthodb.org/?gene=A0A8C2LGD6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10824", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10824", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10824:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10824:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04775", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04775", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08840", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08840", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035294864", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294864", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LGD6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LGD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGD6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MIQVIATPSNALADEPVSIRATGLPPSQIVTIKATLKDEKENLFQSKAFYKANKAGEVDLERASALGGDYVGVHPMGLFWSLKPKKVFQRLLKKDVMNTPFLITLDLYDYVCLQDSATIKPKASQIVQRWFAGPGVQRKQIREGRVRGALFLPPGEGPFPGILDLFGMVGGLVEFRASLLASHGFAVLALAYFAYEDLPDKLLETDLEYFEEAADFLLAHPKIQQPGIGVISTSKGAEIGLAMACYLKQVVATVCINGSSAILDFPLRYRDLVVTAIPRARERIQVHASGAVRFRSFIDDPWNKLNLHSILPVEKAQGWILFIVGENDESLDSKACAQRAMDQLHSHGRSSGRMLAYPGAGHLIEPPYSPCCFASWTFGMPNPLLWGGDPIAHAAAQEHSWREIQKFFRQHLTQSRSKL", "length": 419, "header": "tr|A0A8C2LGD6-1|A0A8C2LGD6_CRIGR Isoform 1 of Acyl-coenzyme A amino acid N-acyltransferase 2 OS=Cricetulus griseus OX=10029 GN=LOC100756541 PE=3 SV=1 CANONICAL=A0A8C2LGD6-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LGD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGD6/entry#A0A8C2LGD6-1", "sequence": { "sequence": "MIQVIATPSNALADEPVSIRATGLPPSQIVTIKATLKDEKENLFQSKAFYKANKAGEVDLERASALGGDYVGVHPMGLFWSLKPKKVFQRLLKKDVMNTPFLITLDLYDYVCLQDSATIKPKASQIVQRWFAGPGVQRKQIREGRVRGALFLPPGEGPFPGILDLFGMVGGLVEFRASLLASHGFAVLALAYFAYEDLPDKLLETDLEYFEEAADFLLAHPKIQQPGIGVISTSKGAEIGLAMACYLKQVVATVCINGSSAILDFPLRYRDLVVTAIPRARERIQVHASGAVRFRSFIDDPWNKLNLHSILPVEKAQGWILFIVGENDESLDSKACAQRAMDQLHSHGRSSGRMLAYPGAGHLIEPPYSPCCFASWTFGMPNPLLWGGDPIAHAAAQEHSWREIQKFFRQHLTQSRSKL", "length": 419, "header": "tr|A0A8C2LGD6-1|A0A8C2LGD6_CRIGR Isoform 1 of Acyl-coenzyme A amino acid N-acyltransferase 2 OS=Cricetulus griseus OX=10029 GN=LOC100756541 PE=3 SV=1 CANONICAL=A0A8C2LGD6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035302805", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302805" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LGM7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGM7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tmem239", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGM7", "locus": {} } ], "crossref": [ { "id": "100771084", "url": "https://www.ncbi.nlm.nih.gov/gene/100771084", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031694", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031694", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771084", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771084", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RWCMCHV", "url": "https://omabrowser.org/oma/group/RWCMCHV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LGM7", "url": "https://www.orthodb.org/?gene=A0A8C2LGM7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR37356", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37356", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37356:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37356:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15841", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15841", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035302805", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302805", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LGM7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LGM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGM7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQQPRVETDIIGAGEGPQRAVPWSAWVTRQDWVRWWACHMPRSWSQWWNTSGWRQPLQRMLWGLEGTLYLLLALMLCHALFTTGSHLLSSLWPVVAVVWSHLLPAILLLVLSAMPALLFAASFLLLFSTLLSLVGLLTSMTHPGYAQDLD", "length": 150, "header": "tr|A0A8C2LGM7-1|A0A8C2LGM7_CRIGR Isoform 1 of Transmembrane protein 239 OS=Cricetulus griseus OX=10029 GN=Tmem239 PE=4 SV=1 CANONICAL=A0A8C2LGM7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LGM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGM7/entry#A0A8C2LGM7-1", "sequence": { "sequence": "MQQPRVETDIIGAGEGPQRAVPWSAWVTRQDWVRWWACHMPRSWSQWWNTSGWRQPLQRMLWGLEGTLYLLLALMLCHALFTTGSHLLSSLWPVVAVVWSHLLPAILLLVLSAMPALLFAASFLLLFSTLLSLVGLLTSMTHPGYAQDLD", "length": 150, "header": "tr|A0A8C2LGM7-1|A0A8C2LGM7_CRIGR Isoform 1 of Transmembrane protein 239 OS=Cricetulus griseus OX=10029 GN=Tmem239 PE=4 SV=1 CANONICAL=A0A8C2LGM7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LGM7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGM7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LGN0-1", "uniprot_ac": "A0A8C2LGN0", "uniprot_id": "A0A8C2LGN0_CRIGR", "mass": { "chemical_mass": 32779.0, "monoisotopic_mass": 32779.0 }, "refseq": { "ac": "XP_027244578", "name": "FK506-binding protein-like isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244578" }, "gene_names": [ { "name": "Fkbpl", "type": "recommended", "evidence": [ { "id": "A0A8C2LGN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGN0" } ] }, { "name": "Fkbpl", "type": "synonym", "evidence": [ { "id": "XP_027244578", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244578" } ] } ], "protein_names": [ { "name": "FK506-binding protein-like isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027244578", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244578" }, { "id": "A0A8C2LGN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGN0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027244578", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244578" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LGN0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGN0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Fkbpl", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGN0", "locus": {} } ], "crossref": [ { "id": "113832490", "url": "https://www.ncbi.nlm.nih.gov/gene/113832490", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013105", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013105", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050754", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050754", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113832490", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113832490", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LGN0", "url": "https://www.orthodb.org/?gene=A0A8C2LGN0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46512", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46512", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46512:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46512:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07719", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07719", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027244578", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027244578", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LGN0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LGN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGN0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQEQAQAQDAAVAAAPRGQREESAPEPAAAEVELPVPALKADAARARACSGGDLWFCPDGSFVKKVVVRGRGLDKPKLGSQCRVLASGFPFGSGMPEGWAELTIGLGRWREAAWGELTEKCLESMRQGEEAEILLPGCPAPLARLALDSFTPGRDSWELAAAEKEALASQERAMGTELFRAGDPRGAARCYGRALRMLLTLPPPRTPGQTVLYANLAACQLLLGQPGLATQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAADPQNRAAQEQLGRVVTEGKKQDAGLARGLRKMFC", "length": 307, "header": "tr|A0A8C2LGN0-1|A0A8C2LGN0_CRIGR Isoform 1 of FK506-binding protein-like isoform X2 OS=Cricetulus griseus OX=10029 GN=Fkbpl PE=4 SV=1 CANONICAL=A0A8C2LGN0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LGN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGN0/entry#A0A8C2LGN0-1", "sequence": { "sequence": "MQEQAQAQDAAVAAAPRGQREESAPEPAAAEVELPVPALKADAARARACSGGDLWFCPDGSFVKKVVVRGRGLDKPKLGSQCRVLASGFPFGSGMPEGWAELTIGLGRWREAAWGELTEKCLESMRQGEEAEILLPGCPAPLARLALDSFTPGRDSWELAAAEKEALASQERAMGTELFRAGDPRGAARCYGRALRMLLTLPPPRTPGQTVLYANLAACQLLLGQPGLATQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAADPQNRAAQEQLGRVVTEGKKQDAGLARGLRKMFC", "length": 307, "header": "tr|A0A8C2LGN0-1|A0A8C2LGN0_CRIGR Isoform 1 of FK506-binding protein-like isoform X2 OS=Cricetulus griseus OX=10029 GN=Fkbpl PE=4 SV=1 CANONICAL=A0A8C2LGN0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LGN0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LGN0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003510454", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510454" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LHD3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHD3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100771142", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHD3", "locus": {} } ], "crossref": [ { "id": "100771142", "url": "https://www.ncbi.nlm.nih.gov/gene/100771142", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026845", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026845", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771142", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771142", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MWHSLSC", "url": "https://omabrowser.org/oma/group/MWHSLSC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LHD3", "url": "https://www.orthodb.org/?gene=A0A8C2LHD3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16165", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16165", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16165:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16165:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06312", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06312", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003510454", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510454", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LHD3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LHD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHD3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRQLKGYKILTVGLVFLVLVICLIMSWLEPMNRWLPPPNAVSEYVSETINWDRLPQELANLTSLLYWPPTGRNRDDFLASTSPKTSTYRLKSPAQATYTLGSNLEAILVARDHQGRPKIHGGDLFRAKLLGPELKAGVPGEVKDLENGTYLLSFPLLWAGQAQVQVRLIHSSEAVGVLQRIWREKRATVDFRGYFRGRDGTEETVICNVDPQSTGAKGPTCRYSDVVSGEVWFCAQPSTLPCNALVGHSSGSYLKVTTPRDEDLLARRVTDQPLPSGMSPILVTPAATGNMSDMALPSRPPCRPGHLSPKPSGFFHQDRWHSMFCSSRSFPTVNSILNCLAGRIVYMMGDSTLRQWWEYLRDTVPSLKPVDLHVTYQTGPLMAVDTTRGAVLHWRAHGWPLRSLRTPVASLHSVARELHGLAGGPYTVVVLGMGAHFTTFPPSIFARRLAGIREAVRALLEREPSTLVIIKLANTGYKSVYGSDWLTLQVNRFLRAAFVGLPVAFVDAWEMTSSLAVPDNIHPNKLIVRNEVELFLSFICPT", "length": 542, "header": "tr|A0A8C2LHD3-1|A0A8C2LHD3_CRIGR Isoform 1 of NXPE family member 3 OS=Cricetulus griseus OX=10029 GN=LOC100771142 PE=3 SV=1 CANONICAL=A0A8C2LHD3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LHD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHD3/entry#A0A8C2LHD3-1", "sequence": { "sequence": "MRQLKGYKILTVGLVFLVLVICLIMSWLEPMNRWLPPPNAVSEYVSETINWDRLPQELANLTSLLYWPPTGRNRDDFLASTSPKTSTYRLKSPAQATYTLGSNLEAILVARDHQGRPKIHGGDLFRAKLLGPELKAGVPGEVKDLENGTYLLSFPLLWAGQAQVQVRLIHSSEAVGVLQRIWREKRATVDFRGYFRGRDGTEETVICNVDPQSTGAKGPTCRYSDVVSGEVWFCAQPSTLPCNALVGHSSGSYLKVTTPRDEDLLARRVTDQPLPSGMSPILVTPAATGNMSDMALPSRPPCRPGHLSPKPSGFFHQDRWHSMFCSSRSFPTVNSILNCLAGRIVYMMGDSTLRQWWEYLRDTVPSLKPVDLHVTYQTGPLMAVDTTRGAVLHWRAHGWPLRSLRTPVASLHSVARELHGLAGGPYTVVVLGMGAHFTTFPPSIFARRLAGIREAVRALLEREPSTLVIIKLANTGYKSVYGSDWLTLQVNRFLRAAFVGLPVAFVDAWEMTSSLAVPDNIHPNKLIVRNEVELFLSFICPT", "length": 542, "header": "tr|A0A8C2LHD3-1|A0A8C2LHD3_CRIGR Isoform 1 of NXPE family member 3 OS=Cricetulus griseus OX=10029 GN=LOC100771142 PE=3 SV=1 CANONICAL=A0A8C2LHD3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"evidence": [ { "id": "A0A8C2LHF4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHF4/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 474", "type": "synonym", "evidence": [ { "id": "XP_035294929", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294929" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035294929", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294929" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LHF4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHF4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100765181", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHF4", "locus": {} } ], "crossref": [ { "id": "100765181", "url": "https://www.ncbi.nlm.nih.gov/gene/100765181", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026319", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026319", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765181", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765181", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LHF4", "url": "https://www.orthodb.org/?gene=A0A8C2LHF4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13555", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13555", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13555:SF67", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13555:SF67", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13913", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13913", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035294929", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294929", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LHF4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LHF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHF4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERGKEGIPTQSQRTFHRSKEPTFLIHQAALPSDSHSTTLPETQYGDLTENIKTNTQKRRPGTVILSKRSRRTMSESQLSPPVIPCRRPAFRICYICGREYGSQSLAIHEPQCLEKWRIENSKLPKHLRRPEPSKPQPISGSGSYSLQAANEEAFQSAQAQLLPCDNCGRTFLPDRLLVHQRSCKPKGEHHRTLGTDGPDVPTGLKKASSGVPARPRTLICYICGREFGTLSLPIHEPKCLEKWKIENDRLPKGLRQPLPQKPQALPTGHPGQEGASQAALVPCQNCGRTFGPDRLPVHQRSCKPQPSGPKILGSNLERKGGPNVPTNSKQQRNMAAPNEDKVTGVM", "length": 347, "header": "tr|A0A8C2LHF4-1|A0A8C2LHF4_CRIGR Isoform 1 of Zinc finger protein 474 OS=Cricetulus griseus OX=10029 GN=LOC100765181 PE=4 SV=1 CANONICAL=A0A8C2LHF4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LHF4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHF4/entry#A0A8C2LHF4-1", "sequence": { "sequence": "MERGKEGIPTQSQRTFHRSKEPTFLIHQAALPSDSHSTTLPETQYGDLTENIKTNTQKRRPGTVILSKRSRRTMSESQLSPPVIPCRRPAFRICYICGREYGSQSLAIHEPQCLEKWRIENSKLPKHLRRPEPSKPQPISGSGSYSLQAANEEAFQSAQAQLLPCDNCGRTFLPDRLLVHQRSCKPKGEHHRTLGTDGPDVPTGLKKASSGVPARPRTLICYICGREFGTLSLPIHEPKCLEKWKIENDRLPKGLRQPLPQKPQALPTGHPGQEGASQAALVPCQNCGRTFGPDRLPVHQRSCKPQPSGPKILGSNLERKGGPNVPTNSKQQRNMAAPNEDKVTGVM", "length": 347, "header": "tr|A0A8C2LHF4-1|A0A8C2LHF4_CRIGR Isoform 1 of Zinc finger protein 474 OS=Cricetulus griseus OX=10029 GN=LOC100765181 PE=4 SV=1 CANONICAL=A0A8C2LHF4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614106.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 27, 2016 this sequence version replaced XP_003505006.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003505006", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505006" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LHK6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHK6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tmem267", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHK6", "locus": {} } ], "crossref": [ { "id": "100764864", "url": "https://www.ncbi.nlm.nih.gov/gene/100764864", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026572", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026572", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764864", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764864", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LHK6", "url": "https://www.orthodb.org/?gene=A0A8C2LHK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13628", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13628", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13628:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13628:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_003505006", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505006", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LHK6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LHK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHK6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMASKVEKTHALQQCFSTESLISSLGLGIFCLVADRFLRFSIIHQNDWLRALSDNIVHGVIGMWSWAVVIGIKKKADFGEVLLAGFLASVIDIDHFFLAGSLSLKAALTLPRRPFLHCSTVIPVAVVSVKLAMHLLRLRDTWCFLPWMLFISWASHHIRDGIRHGLWICPFGKTSPLPFWLYVITTLSLPHMCSFLMYLTGTRQVMSSKQEMRIDV", "length": 216, "header": "tr|A0A8C2LHK6-1|A0A8C2LHK6_CRIGR Isoform 1 of Transmembrane protein 267 OS=Cricetulus griseus OX=10029 GN=Tmem267 PE=4 SV=1 CANONICAL=A0A8C2LHK6-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LHK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHK6/entry#A0A8C2LHK6-1", "sequence": { "sequence": "MMASKVEKTHALQQCFSTESLISSLGLGIFCLVADRFLRFSIIHQNDWLRALSDNIVHGVIGMWSWAVVIGIKKKADFGEVLLAGFLASVIDIDHFFLAGSLSLKAALTLPRRPFLHCSTVIPVAVVSVKLAMHLLRLRDTWCFLPWMLFISWASHHIRDGIRHGLWICPFGKTSPLPFWLYVITTLSLPHMCSFLMYLTGTRQVMSSKQEMRIDV", "length": 216, "header": "tr|A0A8C2LHK6-1|A0A8C2LHK6_CRIGR Isoform 1 of Transmembrane protein 267 OS=Cricetulus griseus OX=10029 GN=Tmem267 PE=4 SV=1 CANONICAL=A0A8C2LHK6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LHK6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHK6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LHK6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHK6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764864", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764864", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LHK6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHK6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LHS3-1", "uniprot_ac": "A0A8C2LHS3", "uniprot_id": "A0A8C2LHS3_CRIGR", "mass": { "chemical_mass": 39071.0, "monoisotopic_mass": 39071.0 }, "refseq": { "ac": "XP_003506688", "name": "magnesium transporter NIPA2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506688" }, "gene_names": [ { "name": "Nipa2", "type": "recommended", "evidence": [ { "id": "A0A8C2LHS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHS3" } ] }, { "name": "Nipa2", "type": "synonym", "evidence": [ { "id": "XP_003506688", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506688" } ] } ], "protein_names": [ { "name": "Magnesium transporter NIPA2", "type": "synonym", "evidence": [ { "id": "A0A8C2LHS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHS3/entry#names_and_taxonomy" } ] }, { "name": "magnesium transporter NIPA2", "type": "synonym", "evidence": [ { "id": "XP_003506688", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506688" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614268.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003506688", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506688" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LHS3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHS3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Nipa2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHS3", "locus": {} } ], "crossref": [ { "id": "100759242", "url": "https://www.ncbi.nlm.nih.gov/gene/100759242", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008521", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008521", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759242", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759242", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PMVYISI", "url": "https://omabrowser.org/oma/group/PMVYISI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LHS3", "url": "https://www.orthodb.org/?gene=A0A8C2LHS3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12570", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12570", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12570:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12570:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003506688", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506688", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LHS3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LHS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHS3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLGRGKYDFYIGLGLAMTSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLLSMGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAPKEEEIETLSEMSHKLGDPGFVVFATFVVIVAFIFIFVVGPRHGQTNILVYITICSMIGAFSVSCVKGLGITIKELLAGKPVLQHPLAWILLLSLVVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLACSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLLHAFKDVSFSLASLPVSFRKDEKAVNGSLSSMYEVLNNNEEGLPCGIEHTTGDTISRRNGNLTSF", "length": 360, "header": "tr|A0A8C2LHS3-1|A0A8C2LHS3_CRIGR Isoform 1 of Magnesium transporter NIPA2 OS=Cricetulus griseus OX=10029 GN=Nipa2 PE=3 SV=1 CANONICAL=A0A8C2LHS3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LHS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHS3/entry#A0A8C2LHS3-1", "sequence": { "sequence": "MSLGRGKYDFYIGLGLAMTSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLLSMGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAPKEEEIETLSEMSHKLGDPGFVVFATFVVIVAFIFIFVVGPRHGQTNILVYITICSMIGAFSVSCVKGLGITIKELLAGKPVLQHPLAWILLLSLVVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLACSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLLHAFKDVSFSLASLPVSFRKDEKAVNGSLSSMYEVLNNNEEGLPCGIEHTTGDTISRRNGNLTSF", "length": 360, "header": "tr|A0A8C2LHS3-1|A0A8C2LHS3_CRIGR Isoform 1 of Magnesium transporter NIPA2 OS=Cricetulus griseus OX=10029 GN=Nipa2 PE=3 SV=1 CANONICAL=A0A8C2LHS3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LHS3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHS3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LHS3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHS3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759242", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759242", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZUV1-1", "protein_name": "NIPA magnesium transporter 2", "gene_name": "Nipa2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLGRGKYDFYIGLGLAMTSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLLSMGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAPKEEEIETLNEMSHKLGDPGFVVFATFVVIVALIFIFVVGPRHGQTNILVYITICSVIGAFSVSCVKGLGITIKELLAGKPVLQHPLAWILLLSLVVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLLHAFKDVSFSLASLPVTFRKDEKAVNGNLSNMYEVLNNNEEDLPCGIEHTGENISRRNGNLTSF", "length": 359 }, "evidence": [ { "id": "A0A8C2LHS3", "url": "https://omabrowser.org/oma/group/A0A8C2LHS3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1NBX2-1", "protein_name": "Non imprinted in Prader-Willi/Angelman syndrome 2", "gene_name": "NIPA2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSQARGRYDFCIGLVLAMSSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLLSMGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSFFLNEKLNLHGKIGCLLSILGSTVMVIHAPQEEEVETLDEMSNKLRDPGFVVFATLVVIVSLILIVVVGPRHGQTNILVYITICSVIGALSVSCVKGLGIAIKELFAGKPVLKRPLSWILLLSLIVCVSTQINYLNRALDIFNTSIVTPIYYVIFTTSVLTCSAILFKEWQHMAADDIIGTFSGFLTIIVGIFLLHAFKDVNFTLANLPVSLRKDDRAANGSLLSTYDCFNHDEESSTCVSEIQSTESLSARRNGSLSAY", "length": 361 }, "evidence": [ { "id": "A0A8C2LHS3", "url": "https://omabrowser.org/oma/group/A0A8C2LHS3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q3SWX0-1", "protein_name": "Magnesium transporter NIPA2", "gene_name": "NIPA2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSQGHGKYDFYIGLGLAMSSSIFIGGSFILKKKGLLRLARKGSTRAGQGGHAYLKEWLWWAGLLSMGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAPKEEEIETLNEMSHKLGDPGFVVFATLVVIVSLILIFVVGPRHGQTNILVYITICSVIGAVSVSCAKGLGIAIKELFAGKPVLQHPLTWILLLSLIVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVITCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLLHAFKDVSFSLSSLPVSFRKDEKAVNGSLSSMYEVLNNNEESLTCGIEQHTAENISRRNGNLTAF", "length": 360 }, "evidence": [ { "id": "A0A8C2LHS3", "url": "https://omabrowser.org/oma/group/A0A8C2LHS3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8N8Q9-1", "protein_name": "Magnesium transporter NIPA2", "gene_name": "NIPA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSQGRGKYDFYIGLGLAMSSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLLSMGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAPKEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITICSVIGAFSVSCVKGLGIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLLHAFKDVSFSLASLPVSFRKDEKAMNGNLSNMYEVLNNNEESLTCGIEQHTGENVSRRNGNLTAF", "length": 360 }, "evidence": [ { "id": "A0A8C2LHS3", "url": "https://omabrowser.org/oma/group/A0A8C2LHS3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JJC8-1", "protein_name": "Magnesium transporter NIPA2", "gene_name": "Nipa2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"https://www.uniprot.org/uniprotkb/A0A8C2LHY6" } ] }, { "name": "LOC100773747", "type": "synonym", "evidence": [ { "id": "XP_027253886", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253886" } ] } ], "protein_names": [ { "name": "Protocadherin beta-14 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A8C2LHY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHY6/entry#names_and_taxonomy" } ] }, { "name": "protocadherin beta-14 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027253886", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253886" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027253886.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027253886", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253886" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LHY6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHY6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100773747", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHY6", "locus": {} } ], "crossref": [ { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100773747", "url": "https://www.ncbi.nlm.nih.gov/gene/100773747", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002126", "url": 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"METPLHKALLKRQVTAIVFLFLLWEAGSVTIKYSVLEETDRGSLVGNLAKDLGLGLRDLVTRGAQILNKGNKQLLQLEQKSGKLVLKEKLDREELCGSMDPCILQFQVLLKSPVQFIQGEIQLQDVNDHAPEFMEDEILLKILESSHPGAKFPLKIAQDLDVGSNTVQNYTISTNSHFHLLTRNHSDGRKYPELVLDNALDREEQAEVRLTLTALDSGSPPKTGTTQVLVMVLDINDNAPEFAQGLYEVQVQENSPVGSLVLTVSARDLDAGTNAEMTYSLFQASKQVLRAFEINTDTGEIRIRKLLDFEEIQSYRMEIEASDGGGLSGKCTVVIDVMDVNDNAPELSMSLLISDIPENAPETVVAIFGISDPDSGENGEMVCSIQDRLPFLLKPTEENFYTLVTEGALDRESRAEYNITITVTDLGTPRLTTQHTITVRVSDVNDNAPAFTQTSYTLFVQENNSPALHIGTISATDSDSGSNAHITYSLLPTHDPQLALSSLISINADNGQLFALRALDYEALQTFEFRVGATDQGSPALSSQALVRVLVLDANDNAPFVLYPLQNASAPCTELLPRAAEPGYLVTKVVAVDSDSGQNAWLSFQMLKATEPGLFTVWAHNGEVRTSRLLSERDAPKHRLLLLVKDNGDPPRSATVTLHVLVVDGFSQPYLPLPEVVRESSQEEDALTLYLVIALASVSSLFLLSVLLFVAVRLCRRARASSLGGCSVPEGPFPGHLVDVSGAGTLSQSYQYEVCLTGGTGTNEFKFLKPVLPNFLNEGVYSNGEENSNFRDHLGFS", "length": 797, "header": "tr|A0A8C2LHY6-1|A0A8C2LHY6_CRIGR Isoform 1 of Protocadherin beta-14 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100773747 PE=4 SV=1 CANONICAL=A0A8C2LHY6-1" }, 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Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LHY6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHY6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LHY6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHY6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773747", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773747", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LHY6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LHY6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", 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NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614404.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003507605", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507605" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LI48", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI48" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100755586", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI48", "locus": {} } ], "crossref": [ { "id": "100755586", "url": "https://www.ncbi.nlm.nih.gov/gene/100755586", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755586", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755586", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QQITMVM", "url": "https://omabrowser.org/oma/group/QQITMVM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LI48", "url": "https://www.orthodb.org/?gene=A0A8C2LI48", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7H526", "url": "https://www.orthodb.org/?gene=A0A9J7H526", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10476", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10476", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03357", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03357", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003507605", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507605", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LI48", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LI48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI48-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H526", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H526", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H526-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H526-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSNMEKHLFNLKFAAKELNRNAKKCDKEEKAEKAKIKKAIQKGNTEVARIHAENAIRQKNQAINFLRMSARVDAVAARVQTAVTMGKVTKSMAGVVKSMDATLRSMNLEKISALMDKFEHQFETLDVQTQQMEDTMSSTTTLTTPQNQVDMLLQEMADEAGLDLNMELPQGQTGSVGASVASTEQDELSQRLARLRDQV", "length": 199, "header": "tr|A0A8C2LI48-1|A0A8C2LI48_CRIGR Isoform 1 of Charged multivesicular body protein 1b-2 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100755586 PE=3 SV=1 CANONICAL=A0A8C2LI48-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LI48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI48/entry#A0A8C2LI48-1", "sequence": { "sequence": "MSNMEKHLFNLKFAAKELNRNAKKCDKEEKAEKAKIKKAIQKGNTEVARIHAENAIRQKNQAINFLRMSARVDAVAARVQTAVTMGKVTKSMAGVVKSMDATLRSMNLEKISALMDKFEHQFETLDVQTQQMEDTMSSTTTLTTPQNQVDMLLQEMADEAGLDLNMELPQGQTGSVGASVASTEQDELSQRLARLRDQV", "length": 199, "header": "tr|A0A8C2LI48-1|A0A8C2LI48_CRIGR Isoform 1 of Charged multivesicular body protein 1b-2 isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100755586 PE=3 SV=1 CANONICAL=A0A8C2LI48-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H526-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI48/entry#A0A9J7H526-1", "sequence": { "sequence": "MQEHLFNLKFAAKELNRNAKKCDKEEKAEKAKIKKAIQKGNTEVARIHAENAIRQKNQAINFLRMSARVDAVAARVQTAVTMGKVTKSMAGVVKSMDATLRSMNLEKISALMDKFEHQFETLDVQTQQMEDTMSSTTTLTTPQNQVDMLLQEMADEAGLDLNMELPQGQTGSVGASVASTEQDELSQRLARLRDQV", "length": 196, "header": "tr|A0A9J7H526-1|A0A9J7H526_CRIGR Computationally mapped isoform of Charged multivesicular body protein 1b-2 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100755586 PE=3 SV=1 CANONICAL=A0A8C2LI48-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LI48", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI48" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LI48", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI48" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755586", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755586", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YY63-1", "protein_name": "Charged multivesicular body protein 1B", "gene_name": "CHMP1B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSNMEKHLFNLKFAAKELNRNSKRCDKEEKAEKAKIKKAIQKGNMEVARIHAENAIRQKNQAINFLRMSARVDAVAARVQTAVTMGKVTKSMAGVVKSMDATLKSMNLEKISALMDKFEHQFETLDVQTQQMEDTMSNTTTLTTPQNQVDMLLQEMADEAGMSCHRDWPAFEIKFKLNGAAALCMCFQNTLRLPLHCTRKVYTVWHRCSNICNVGFFTLSLLFFLIH", "length": 227 }, "evidence": [ { "id": "A0A8C2LI48", "url": "https://omabrowser.org/oma/group/A0A8C2LI48/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3V6A6-1", "protein_name": "Charged multivesicular body protein 1B2", "gene_name": "Chmp1b2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSNMEKHLFNLKFAAKELNRNAKKCDKEEKAEKAKIKKAIQKGNTEVARIHAENAIRQKNQAINFLRMSARVDAVAARVQTAVTMGKVTKSMAGVVKSMDATLRSMNLEKISALMDKFEHQFETLDVQTQQMEDTMSSTTTLTTPQNQVDMLLQEMADEAGLDLNMELPQGQTGSVGASVASTEQDELSQRLARLRDQV", "length": 199 }, "evidence": [ { "id": "A0A8C2LI48", "url": "https://omabrowser.org/oma/group/A0A8C2LI48/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P69771-1", "protein_name": "Vacuolar protein-sorting-associated protein 46", "gene_name": "DID2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSRNSAAGLENTLFQLKFTSKQLQKQANKASKEEKQETNKLKRALNENEDISRIYASNAIRKKNERLQLLKLASRVDSVASRVQTAVTMRQVSASMGQVCKGMDKALQNMNLQQITMIMDKFEQQFEDLDTSVNVYEDMGVNSDAMLVDNDKVDELMSKVADENGMELKQSAKLDNVPEIKAKEVNVDDEKEDKLAQRLRALRG", "length": 204 }, "evidence": [ { "id": "A0A8C2LI48", "url": "https://omabrowser.org/oma/group/A0A8C2LI48/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q7ZVB1-1", "protein_name": "Charged multivesicular body protein 1b", "gene_name": "chmp1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSMEKHLFNLKFAAKELQRNSKKCDKEEKAEKVKVKKAIQKGNMEVARIHAENAIRQKNQSVNFLRMSARVDAVAARVQTAVTMNQVTKSMAGVVKGMDATLKSMNLEKISGLMEKFERQFETLDVQTAQMEDSMSSTTTLTTPQGQVDTLMMEMADEAGLDLNMELPQGQTGSVGTSVASAEQDELSQRLAKLRDQV", "length": 199 }, "evidence": [ { "id": "A0A8C2LI48", "url": "https://omabrowser.org/oma/group/A0A8C2LI48/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9SSM4-1", "protein_name": "ESCRT-related protein CHMP1B", "gene_name": "CHMP1B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGNTDKLMNQIFDLKFTSKSLQRQSRKCEKEEKAEKLKVKKAIEKGNMDGARIYAENAIRKRSEQMNYLRLASRLDAVVARLDTQAKMTTITKSMTNIVKSLESSLATGNLQKMSETMDSFEKQFVNMEVQAEFMENAMAGSTSLSTPEGEVNSLMQQVADDYGLEVSVGLPQPAGHAIPTKTEEKVDEDDLSRRLAELKARG", "length": 203 }, "evidence": [ { "id": "A0A8C2LI48", "url": "https://omabrowser.org/oma/group/A0A8C2LI48/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "vacuolar transport", "id": "GO:0007034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007034", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LI48", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI48" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], 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"https://www.ncbi.nlm.nih.gov/protein/XP_027259417" }, "gene_names": [ { "name": "Hrct1", "type": "recommended", "evidence": [ { "id": "A0A8C2LI63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI63" } ] }, { "name": "Hrct1", "type": "synonym", "evidence": [ { "id": "XP_027259417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259417" } ] } ], "protein_names": [ { "name": "Histidine-rich carboxyl terminus protein 1", "type": "synonym", "evidence": [ { "id": "A0A8C2LI63", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI63/entry#names_and_taxonomy" } ] }, { "name": "histidine-rich carboxyl terminus protein 1", "type": "synonym", "evidence": [ { "id": "XP_027259417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259417" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027259417", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259417" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LI63", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI63" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Hrct1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI63", "locus": {} } ], "crossref": [ { "id": "100758508", "url": "https://www.ncbi.nlm.nih.gov/gene/100758508", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031506", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031506", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758508", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758508", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR23009", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23009", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23009:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23009:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15758", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15758", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027259417", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027259417", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LI63", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LI63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI63-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLGLLGSTALVSWIAGTVLAILLLLLLVAICLFHGSQEHDVERNRVRQTRPRLFHGRRGGLLGAFHHHHRHHRGHVSGVTSAGFHHHHHHLHHQRHHSPHRLHHHHHARGARR", "length": 113, "header": "tr|A0A8C2LI63-1|A0A8C2LI63_CRIGR Isoform 1 of Histidine-rich carboxyl terminus protein 1 OS=Cricetulus griseus OX=10029 GN=Hrct1 PE=4 SV=1 CANONICAL=A0A8C2LI63-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LI63-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LI63/entry#A0A8C2LI63-1", "sequence": { "sequence": "MLGLLGSTALVSWIAGTVLAILLLLLLVAICLFHGSQEHDVERNRVRQTRPRLFHGRRGGLLGAFHHHHRHHRGHVSGVTSAGFHHHHHHLHHQRHHSPHRLHHHHHARGARR", "length": 113, "header": "tr|A0A8C2LI63-1|A0A8C2LI63_CRIGR Isoform 1 of Histidine-rich carboxyl terminus protein 1 OS=Cricetulus griseus OX=10029 GN=Hrct1 PE=4 SV=1 CANONICAL=A0A8C2LI63-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613647.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007609395", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007609395" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LIH3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LIH3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tmem69", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LIH3", "locus": {} } ], "crossref": [ { "id": "100774937", "url": "https://www.ncbi.nlm.nih.gov/gene/100774937", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR021836", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021836", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774937", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774937", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WYAFLIS", "url": "https://omabrowser.org/oma/group/WYAFLIS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LIH3", "url": "https://www.orthodb.org/?gene=A0A8C2LIH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15887", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15887", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15887:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15887:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11911", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11911", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007609395", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007609395", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LIH3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LIH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LIH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LIH3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLHFIQKFSAASSKMLKYPSIVRPRANRIDVFSSKTSVQQNLSPLSPRSWLPTSFQVCMKNIQCYHASPCNFKRHQKEAFLPSKPPSTITYLPDSPKPALYISLVGLIPFIAPPLTMVITKSYIPILAFTQMAYGAGFLAFLGGVRWGFALPESSPAKPDYINLASSMSPVLFSWVAILFSERLTEAIVTVIMGLGIALHNEIFLLPHYPNWFKALRLVSTLVAFFSFVVTLILKSVYPEKGPKRF", "length": 246, "header": "tr|A0A8C2LIH3-1|A0A8C2LIH3_CRIGR Isoform 1 of Transmembrane protein 69 OS=Cricetulus griseus OX=10029 GN=Tmem69 PE=4 SV=1 CANONICAL=A0A8C2LIH3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LIH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LIH3/entry#A0A8C2LIH3-1", "sequence": { "sequence": "MLHFIQKFSAASSKMLKYPSIVRPRANRIDVFSSKTSVQQNLSPLSPRSWLPTSFQVCMKNIQCYHASPCNFKRHQKEAFLPSKPPSTITYLPDSPKPALYISLVGLIPFIAPPLTMVITKSYIPILAFTQMAYGAGFLAFLGGVRWGFALPESSPAKPDYINLASSMSPVLFSWVAILFSERLTEAIVTVIMGLGIALHNEIFLLPHYPNWFKALRLVSTLVAFFSFVVTLILKSVYPEKGPKRF", "length": 246, "header": "tr|A0A8C2LIH3-1|A0A8C2LIH3_CRIGR Isoform 1 of Transmembrane protein 69 OS=Cricetulus griseus OX=10029 GN=Tmem69 PE=4 SV=1 CANONICAL=A0A8C2LIH3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LIH3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LIH3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LIH3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LIH3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774937", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774937", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BQ47-1", "protein_name": "Transmembrane protein 69", "gene_name": "TMEM69", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPNMLRFIQKFSRASSKMLKYPSTVGLGASGRIETLCYKTSLQQNFPRLFPRPWLFPSFPVCRSKTRYYHTSPCSFKKREQAVLPARPPRTISHLPDSPKPALYITLAGLVPFVAPPLVMVITETYIPVLAFTQVAYGASVLSFLGGVRWGFALPEGSPAKPDFLNLANSTAPVMFSWFALFISERLSEAIVTVIIGLGIALHVEVFLLPHYPNWFKALRIVVTLVAFFSFVITLLVKGIYPEKGPKRPGQVE", "length": 254 }, "evidence": [ { "id": "A0A8C2LIH3", "url": "https://omabrowser.org/oma/group/A0A8C2LIH3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1QUY4-1", "protein_name": "Transmembrane protein 69", "gene_name": "tmem69", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLASIIGRQILGNFRGSSSLLQLSRKLACSGQQTVNFSTLLTRCLNGQFLPRHGTSAVLGSQSFHWSVHRLKKQPQGEESPPRELDLLRYDMKHLKNAPKPALYLGLAGLIPFVSAPLLMAVTELYYSDVAFAQVAYGASIVSFLGGIRWGFALPAGSPEKPDWLNLANSVVPSLIAWTALLFQHDITSSAMIVIIGLGIALHYDLSLLPTYPSWFKALRAILTIVAFLSLLGTLIIKQVYPEKKFIRD", "length": 249 }, "evidence": [ { "id": "A0A8C2LIH3", "url": "https://omabrowser.org/oma/group/A0A8C2LIH3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 41, "end_pos": 43 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LIJ5-1", "uniprot_ac": "A0A8C2LIJ5", "uniprot_id": "A0A8C2LIJ5_CRIGR", "mass": { "chemical_mass": 254542.0, "monoisotopic_mass": 254542.0 }, "refseq": { "ac": "XP_003514927", "name": "protein KIAA0100 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514927" }, "gene_names": [ { "name": "LOC100761624", "type": "recommended", "evidence": [ { "id": "A0A8C2LIJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LIJ5" } ] }, { "name": "LOC100761624", "type": "synonym", "evidence": [ { "id": "XP_003514927", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514927" } ] } ], "protein_names": [ { "name": "Protein KIAA0100 isoform X3", "type": "synonym", "evidence": [ { "id": "A0A8C2LIJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LIJ5/entry#names_and_taxonomy" } ] }, { "name": "protein KIAA0100 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003514927", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514927" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 5285 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003617063.1) and transcript sequence (IACG01058826.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003514927.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003514927", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514927" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LIJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LIJ5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100761624", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LIJ5", "locus": {} } ], "crossref": [ { "id": "100761624", "url": "https://www.ncbi.nlm.nih.gov/gene/100761624", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045167", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045167", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761624", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761624", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LIJ5", "url": "https://www.orthodb.org/?gene=A0A8C2LIJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15678", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15678", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15678:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15678:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003514927", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514927", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LIJ5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LIJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LIJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LIJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLFLSALLVLLLVALSALFLGRWLVVRLATRWCQRKLQAELKIGSFRFFWIQNVSLKFQQHQQTVEIDNLWISSKLLSHDLPHYVALCFGEVRIRTDLQKVSSLSAPFSQNTEVEQKEPSLSPSLLKIFCQLFSIHVEAINIMVLKVATSESLWHIQMSRSRFLVDSDGKSLICQVNLSKINSKILKSGQLEDTCLVELSLALDLCLQVGINSWHLRAITVDVWTLHAELHEGLFHSQLLCQAPGRISKSVSCSDLTENPAEPTLPGLYLLQQLPDQVKVKMENTSVVLSMNSQKRHLTWTLKLLHFLCHRDEDQPPLRSFTARYDMAQMSTELILEDGLLLSQSRQRIVCLNSLKANVQVTTIDLSASLVLNTCIIHYRHQEFSHWLLMLALETQGASSSDLKQRKKRTFPQILAPIIFSTSISNVSVSIQLGDTPPFALGFNSISLDYQHLRPQSIHQRAVLTVDHLCWRVGSESHIQRAPHPPNMHVWGEALVLDSFTLQGSYNQPLGLSSTQSNTLFLDCTIRGLQVEISDICAQCLSRILSLVIPQSEKSAVSRKSLLGESVTLLWKVDLKVEDMNLFTLSALVGASEVRLDTLTVLGSAETSTVGIQGLVLALVKSVTEKMQPCCKAPDIPTPVLGLSMLSLTYHSSIRSLEVQCGAGLTLLWSPPDHMYLYQHVLSTLQCRDLLQATVFPEIVEFHELEPPRSTSELEDHLPEPSPPRRLLNLTLEVSTAKLTAFVAEDKFITLAAESVSLSRHGGSLQAYCPELAAGFDGNSIFNFKEVELQLLPELEEMILHRNPFPVLQTLRNRVWLLSLGSVSVEFPYQYDFSRTLDEAVGVQKWLKGLHRGTRAWASPSPAPLPPDLLLKVQHFSWVFLDDIFEVKLHDNYELMKDESKESAKRLQLLDAKVAALRKQHGELLPARKIEELYASLERKNIEIYIQRSRRLYGNTPMRRALLTWSLAGLELVALADASFHGPEHVLEQVRELDPGSPFPAEGIDLVIQWCRMLKCSVKTFLVRIRDYPRYLFEIRDWRLMGRLAGTEQSGQPCSRRRQILHLGLPWGNVAVERNMPPLKFYHDFHSEIFQYTVVWGPCWDPAWTLIGQCVDLLTKPSADPSPPLPWWDKSRLLFHGDWHMDIEQANLHQLATEDPYNTTENMHWEWSHLSFHWRPGQFVFQGDLDVNVRTASKYDDCCFLHLPDLCMTLDLQWLCHGNPHDHHSVTLRAPEFLPEVPLGQLHDSYRAFRSENLNLSIRMDLTRHSGTISQPRILLYSSTLRWMQNFWATWTSVTRPICRGKLFNNLKPSKKKLGQHYKQLSYTALFPQLQVHYWASFAQQRGIQIECSQGHVFTRGTQRLIPQAGTVMRRLISEWSVTQMVSDLSQVTVHLMASPTEENADHCLDPLITKTHLLSLSSLTYQRHSNRTTEEELSTRDGDPAFHTHQLYLVDLRISWTTTNRDIAFGLYDGYKKAAVLKRNLSTEALKGLKIDPQMSAKKPKRGIPPNAQDPPHVSTPSFSGRPDKGSSGGAYMLQKLIEETDRFVVFTEEESGMSDQLCGIAACQTDDIYNRNCLIELVNCQMVLRGAETEGCVIVSAAKAQLLQCQHHPAWYGDTLKQKTSWTCLLDGMQYFATTESSPTEQDGRQLWLEVKNIEEHRERSLDSVQELMESGQAVGGMVTTTTDWNQPAEAQQAQQVQRIISRCNCRMYYISYSHDIDPELATQIKPPEVHENQEKEDLLKKQEGAVDTFTLIHHELEISTNPAQYAMILDIVNNLLLHVEPKRKEHSEKKQRVRFQLEISSNPEEQRSSILHLQEAVRQHVAQIRHLEKQMYSIMKSLQDDSKNENLLDLNQKLQLQLNQEKANLQLESEELNILIRCFKDFQLQRANKMELRKQQEDVSVVRRTEFYFAQARWRLTEEDGQLGIAELELQRFLYSKVNKSDDTAEHLLELGWFTMNNLLPNAIYKVVLRPQSSCQSGRQLALRLFSKVRPPVGGISVKEHFEVNVVPLTIQLSHQFFHRMMGFFFPGRNVEDDDVGDEEDKSKLVTTGIPVVKPRQLIATDDAAPLGPGKGVTQGLTRSSGVRRSFRKLPEHPVDDIDKMKERAAMNNSFIYIKIPQVPLCVSYKGEKNSVDWGDLNLVLPCLEYHNNTWTWLDFAMAVKRDSRKALVAQVIKEKLRLKPATGSEVRGKLETKSDLNLQQQEEEKARLLIGLSVGDRNPGKKSLFSRRK", "length": 2234, "header": "tr|A0A8C2LIJ5-1|A0A8C2LIJ5_CRIGR Isoform 1 of Protein KIAA0100 isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC100761624 PE=4 SV=1 CANONICAL=A0A8C2LIJ5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LIJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LIJ5/entry#A0A8C2LIJ5-1", "sequence": { "sequence": 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"authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LIX0-1", "uniprot_ac": "A0A8C2LIX0", "uniprot_id": "A0A8C2LIX0_CRIGR", "mass": { "chemical_mass": 12496.0, "monoisotopic_mass": 12496.0 }, "refseq": { "ac": "XP_027242686", "name": "60S ribosomal protein L36a-like isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027242686" }, "gene_names": [ { "name": "LOC107979073", "type": "recommended", "evidence": [ { "id": "A0A8C2LIX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LIX0" } ] }, { "name": "LOC107979073", "type": "synonym", "evidence": [ { "id": "XP_027242686", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027242686" } ] } ], "protein_names": [ { "name": "60S ribosomal protein L36a-like isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027242686", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027242686" }, { "id": "A0A8C2LIX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LIX0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027242686", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027242686" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LIX0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LIX0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC107979073", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LIX0", "locus": {} } ], "crossref": [ { "id": "107979073", "url": "https://www.ncbi.nlm.nih.gov/gene/107979073", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000552", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000552", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011332", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011332", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053708", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053708", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:107979073", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:107979073", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LIX0", "url": "https://www.orthodb.org/?gene=A0A8C2LIX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10369", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10369", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00935", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00935", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027242686", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027242686", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LIX0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LIX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LIX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LIX0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVNVPKTRRTFCKKCDKHQPHKVTQYNKGKDSLYAQGKRHYDRKQSGYGGQTKPIFRKKTKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106, "header": "tr|A0A8C2LIX0-1|A0A8C2LIX0_CRIGR Isoform 1 of 60S ribosomal protein L36a-like isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC107979073 PE=3 SV=1 CANONICAL=A0A8C2LIX0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LIX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LIX0/entry#A0A8C2LIX0-1", "sequence": { "sequence": "MVNVPKTRRTFCKKCDKHQPHKVTQYNKGKDSLYAQGKRHYDRKQSGYGGQTKPIFRKKTKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106, "header": "tr|A0A8C2LIX0-1|A0A8C2LIX0_CRIGR Isoform 1 of 60S ribosomal protein L36a-like isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC107979073 PE=3 SV=1 CANONICAL=A0A8C2LIX0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027268091", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268091" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJA2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJA2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100766259", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJA2", "locus": {} } ], "crossref": [ { "id": "cd15228", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15228", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100766259", "url": "https://www.ncbi.nlm.nih.gov/gene/100766259", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766259", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766259", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LJA2", "url": "https://www.orthodb.org/?gene=A0A8C2LJA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR26453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027268091", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268091", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LJA2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LJA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJA2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKNLSVVTQFVLLGIPHTEGLETMLFVLFLSFYIFTLVGNLLILLVIVSSTQLHTPMYFFLCQLSVCDIFFPSVSSPKMLFYLSGNSRAISYAGCVSQLFFYHFLGGTECFLYTVMAYDRFVAICYPLRYSIIMRHRVCALLAMGTSVFGCIHSTFLTTLTFQLPYCGPNMVDYYFCDIPVVMNLACADTSALEMVGFINVGLVPLICFFFILTSYSFIVHSILQIRSTEGRHRAFSTCSAHLTAILIFYMPVIFIYLRPTPSPWLDATVQVLNNLVTPMLNPLIYSLRNKEVKSSLWTALRPLCFLSEQL", "length": 311, "header": "tr|A0A8C2LJA2-1|A0A8C2LJA2_CRIGR Isoform 1 of Olfactory receptor 149 OS=Cricetulus griseus OX=10029 GN=LOC100766259 PE=3 SV=1 CANONICAL=A0A8C2LJA2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LJA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJA2/entry#A0A8C2LJA2-1", "sequence": { "sequence": "MKNLSVVTQFVLLGIPHTEGLETMLFVLFLSFYIFTLVGNLLILLVIVSSTQLHTPMYFFLCQLSVCDIFFPSVSSPKMLFYLSGNSRAISYAGCVSQLFFYHFLGGTECFLYTVMAYDRFVAICYPLRYSIIMRHRVCALLAMGTSVFGCIHSTFLTTLTFQLPYCGPNMVDYYFCDIPVVMNLACADTSALEMVGFINVGLVPLICFFFILTSYSFIVHSILQIRSTEGRHRAFSTCSAHLTAILIFYMPVIFIYLRPTPSPWLDATVQVLNNLVTPMLNPLIYSLRNKEVKSSLWTALRPLCFLSEQL", "length": 311, "header": "tr|A0A8C2LJA2-1|A0A8C2LJA2_CRIGR Isoform 1 of Olfactory receptor 149 OS=Cricetulus griseus OX=10029 GN=LOC100766259 PE=3 SV=1 CANONICAL=A0A8C2LJA2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 261, "start_aa": "Thr", "end_pos": 261, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr261", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJA2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJA2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJA2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJA2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100766259", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766259", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJA2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJA2" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJA2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJA2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJA2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJA2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LJA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJA2" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": 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"count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LJC6-1", "uniprot_ac": "A0A8C2LJC6", "uniprot_id": "A0A8C2LJC6_CRIGR", "mass": { "chemical_mass": 155439.0, "monoisotopic_mass": 155439.0 }, "refseq": { "ac": "XP_027247747", "name": "ankyrin repeat domain-containing protein 50", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247747" }, "gene_names": [ { "name": "Ankrd50", "type": "recommended", "evidence": [ { "id": "A0A8C2LJC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJC6" } ] }, { "name": "Ankrd50", "type": "synonym", "evidence": [ { "id": "XP_027247747", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247747" } ] } ], "protein_names": [ { "name": "Ankyrin repeat domain-containing protein 50", "type": "synonym", "evidence": [ { "id": "A0A8C2LJC6", "database": "UniProtKB", "url": 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This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027247747", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027247747" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJC6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJC6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ankrd50", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJC6", "locus": {} } ], "crossref": [ { "id": "100756565", "url": "https://www.ncbi.nlm.nih.gov/gene/100756565", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" 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This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJD0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJD0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755686", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755686", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "terminal bouton", "id": "GO:0043195", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043195", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJD0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJD0" } ], "pmid": "" }, { "name": "SNARE complex", "id": "GO:0031201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031201", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJD0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJD0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of neurotransmitter secretion", "id": "GO:0046928", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046928", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJD0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJD0" } ], "pmid": "" }, { "name": "synaptic vesicle exocytosis", "id": "GO:0016079", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016079", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJD0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJD0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "syntaxin binding", "id": "GO:0019905", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019905", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJD0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJD0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LKR6-1", "uniprot_ac": "A0A8C2LKR6", "uniprot_id": "A0A8C2LKR6_CRIGR", "mass": { "chemical_mass": 47099.0, "monoisotopic_mass": 47099.0 }, "refseq": { "ac": "XP_007646669", "name": "RNA-binding motif, single-stranded-interacting protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646669" }, "gene_names": [ { "name": "Rbms3", "type": "recommended", "evidence": [ { "id": "A0A8C2LKR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKR6" } ] }, { "name": "Rbms3", "type": "synonym", "evidence": [ { "id": "XP_007646669", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646669" } ] } ], "protein_names": [ { "name": "RNA-binding motif, single-stranded-interacting protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007646669", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646669" }, { "id": "A0A8C2LKR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKR6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613617.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 27, 2016 this sequence version replaced XP_007646669.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007646669", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646669" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LKR6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKR6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rbms3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKR6", "locus": {} } ], "crossref": [ { "id": "cd12472", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12472", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12475", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12475", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100774438", "url": "https://www.ncbi.nlm.nih.gov/gene/100774438", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002343", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002343", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034406", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034406", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774438", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774438", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LGTTGTX", "url": "https://omabrowser.org/oma/group/LGTTGTX/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LJE2", "url": "https://www.orthodb.org/?gene=A0A8C2LJE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LKR6", "url": "https://www.orthodb.org/?gene=A0A8C2LKR6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FYB2", "url": "https://www.orthodb.org/?gene=A0A9J7FYB2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G079", "url": "https://www.orthodb.org/?gene=A0A9J7G079", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JR70", "url": "https://www.orthodb.org/?gene=A0A9J7JR70", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24012", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24012", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007646669", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007646669", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LJE2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LJE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LKR6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LKR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKR6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FY28", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FY28-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FY28-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYB2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FYB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FYB2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G079", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G079", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G079-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G079-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G2J3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2J3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G2J3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G2J3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JR70", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JR70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JR70-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JR70-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JXQ1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JXQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKRLDQPQMYPQYTYYCPQYLQTKQSYAPAPHPMAPPSPSTNSSSNSSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASLKANGVQAQMAKQQEQDPTNLYISNLPISMDEQELENMLKPFGHVISTRILRDANGVSRGVGFARMESTEKCEVVIQHFNGKYLKTPPGIPAPSEPLLCKFADGGQKKRQNQSKYTQNGRPWPREGEAGMALTYDPTAALQNGFYSSPYSLATNRMIPQTSITPFIAASPVSTYQVQSTSWTPHLPYIMQPTGAVITPTMDHPMSMQPTNIVGPLTQQMNHLSLGTAGTIQSQDRIMVLHQLLCQYMTAAPMQGTYIPQYTPVPPTAVSIEGVVADTSPQTVAPSSQDSSGQQQQLAVDTPNEHAPAYSFQQSKP", "length": 431, "header": "tr|A0A8C2LKR6-1|A0A8C2LKR6_CRIGR Isoform 1 of RNA-binding motif, single-stranded-interacting protein 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Rbms3 PE=4 SV=1 CANONICAL=A0A8C2LKR6-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LJE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKR6/entry#A0A8C2LJE2-1", "sequence": { "sequence": "MGKRLDQPQMYPQYTYYCPQYLQTKQSYAPAPHPMAPPSPSTNSSSNSSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASLKANGVQAQMAKQQEQDPTNLYISNLPISMDEQELENMLKPFGHVISTRILRDANGVSRGVGFARMESTEKCEVVIQHFNGKYLKTPPGIPAPSEPLLCKFADGGQKKRQNQSKYTQNGRPWPREGEAGMALTYDPTAALQNGFYSSPYSLATNRMIPQTSITPFIAASPVSTYQVQSTSWTPHLPYIMQPTGAVITPTMDHPMSMQPTNIVGPLTQQMNHLSLGTAGTYMTAAPMQGTYIPQYTPVPPTAVSIEGVVADTSPQTVAPSSQDSSGQQQQLAVDTPNEHAPAYSFQQSKP", "length": 415, "header": "tr|A0A8C2LJE2-1|A0A8C2LKR6_CRIGR Computationally mapped isoform of RNA-binding motif, single-stranded-interacting protein 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Rbms3 PE=4 SV=1 CANONICAL=A0A8C2LKR6-1" }, "locus": {} }, { "isoform_ac": "A0A8C2LKR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKR6/entry#A0A8C2LKR6-1", "sequence": { "sequence": "MGKRLDQPQMYPQYTYYCPQYLQTKQSYAPAPHPMAPPSPSTNSSSNSSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASLKANGVQAQMAKQQEQDPTNLYISNLPISMDEQELENMLKPFGHVISTRILRDANGVSRGVGFARMESTEKCEVVIQHFNGKYLKTPPGIPAPSEPLLCKFADGGQKKRQNQSKYTQNGRPWPREGEAGMALTYDPTAALQNGFYSSPYSLATNRMIPQTSITPFIAASPVSTYQVQSTSWTPHLPYIMQPTGAVITPTMDHPMSMQPTNIVGPLTQQMNHLSLGTAGTIQSQDRIMVLHQLLCQYMTAAPMQGTYIPQYTPVPPTAVSIEGVVADTSPQTVAPSSQDSSGQQQQLAVDTPNEHAPAYSFQQSKP", "length": 431, "header": "tr|A0A8C2LKR6-1|A0A8C2LKR6_CRIGR Isoform 1 of RNA-binding motif, single-stranded-interacting protein 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Rbms3 PE=4 SV=1 CANONICAL=A0A8C2LKR6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FY28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKR6/entry#A0A9J7FY28-1", "sequence": { "sequence": "MGKRLDQPQMYPQYTYYCPQYLQTKQSYAPAPHPMAPPSPSTNSSSNSSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASLKANGVQAQMAKQQEQDPTNLYISNLPISMDEQELENMLKPFGHVISTRILRDANGVSRGVGFARMESTEKCEVVIQHFNGKYLKTPPGIPAPSEPLLCKFADGGQKKRQNQSKYTQNGRPWPREGEAGMALTYDPTAALQNGFYSSPYSLATNRMIPQTSITPFIAASPVSTYQVQSTSWTPHLPYIMQPTGAVITPTMDHPMSMQPTNIVGPLTQQMNHLSLGTAGTIQSQDRIMVLHQLLCQ", "length": 361, "header": "tr|A0A9J7FY28-1|A0A9J7FY28_CRIGR Computationally mapped isoform of RNA-binding motif, single-stranded-interacting protein 3 isoform X8 OS=Cricetulus griseus OX=10029 GN=Rbms3 PE=4 SV=1 CANONICAL=A0A8C2LKR6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FYB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKR6/entry#A0A9J7FYB2-1", "sequence": { "sequence": "MGKRLDQPQMYPQYTYYCPQYLQTKQSYAPAPHPMAPPSPSTNSSSNSSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASLKANGVQAQMAKQQEQDPTNLYISNLPISMDEQELENMLKPFGHVISTRILRDANGVSRGVGFARMESTEKCEVVIQHFNGKYLKTPPGIPAPSEPLLCKFADGGQKKRQNQSKYTQNGRPWPREGEAGMALTYDPTAALQNGFYSSPYSLATNRMIPQTSITPFIAASPVSTYQGAVITPTMDHPMSMQPTNIVGPLTQQMNHLSLGTAGTIQSQDRIMVLHQLLCQYMTAAPMQGTYIPQYTPVPPTAVSIEGVVADTSPQTVAPSSQDSSGQQQQLAVDTPNEHAPAYSFQQSK", "length": 413, "header": "tr|A0A9J7FYB2-1|A0A9J7FYB2_CRIGR Computationally mapped isoform of RNA-binding motif, single-stranded-interacting protein 3 isoform X5 OS=Cricetulus griseus OX=10029 GN=Rbms3 PE=4 SV=1 CANONICAL=A0A8C2LKR6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G079-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKR6/entry#A0A9J7G079-1", "sequence": { "sequence": "MGKRLDQPQMYPQYTYYCPQYLQTKQSYAPAPHPMAPPSPSTNSSSNSSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASLKANGVQAQMAKQQEQDPTNLYISNLPISMDEQELENMLKPFGHVISTRILRDANGVSRGVGFARMESTEKCEVVIQHFNGKYLKTPPGIPAPSEPLLCKFADGGQKKRQNQSKYTQNGRPWPREGEAGMALTYDPTAALQNGFYSSPYSLATNRMIPQTSITPFIAASPVSTYQGAVITPTMDHPMSMQPTNIVGPLTQQMNHLSLGTAGTIQSQDRIMVLHQLLCQYMTAAPMQGTYIPQYTPVPPTAVSIEGVVADTSPQTVAPSSQDSSGQQQQLAVDTPNEHAPAYSFQQSKP", "length": 414, "header": "tr|A0A9J7G079-1|A0A9J7G079_CRIGR Computationally mapped isoform of RNA-binding motif, single-stranded-interacting protein 3 isoform X4 OS=Cricetulus griseus OX=10029 GN=Rbms3 PE=4 SV=1 CANONICAL=A0A8C2LKR6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G2J3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKR6/entry#A0A9J7G2J3-1", "sequence": { "sequence": "MGKRLDQPQMYPQYTYYCPQYLQTKQSYAPAPHPMAPPSPSTNSSSNSSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASLKANGVQAQMAKQQEQDPTNLYISNLPISMDEQELENMLKPFGHVISTRILRDANGVSRGVGFARMESTEKCEVVIQHFNGKYLKTPPGIPAPSEPLLCKFADGGQKKRQNQSKYTQNGRPWPREGEAGMALTYDPTAALQNGFYSSPYSLATNRMIPQTSITPFIAASPVSTYQVQSTSWTPHLPYIMQPTGAVITPTMDHPMSMQPTNIVGPLTQQMNHLSLGTAGTYMTAAPMQGTYIPQYTPVPPTAVSIETVAPSSQDSSGQQQQLAVDTPNEHAPAYSFQQSKP", "length": 406, "header": "tr|A0A9J7G2J3-1|A0A9J7G2J3_CRIGR Computationally mapped isoform of RNA-binding motif, single-stranded-interacting protein 3 isoform X6 OS=Cricetulus griseus OX=10029 GN=Rbms3 PE=4 SV=1 CANONICAL=A0A8C2LKR6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JR70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKR6/entry#A0A9J7JR70-1", "sequence": { "sequence": "MGKRLDQPQMYPQYTYYCPQYLQTKQSYAPAPHPMAPPSPSTNSSSNSSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASLKANGVQAQMAKQQEQDPTNLYISNLPISMDEQELENMLKPFGHVISTRILRDANGVSRGVGFARMESTEKCEVVIQHFNGKYLKTPPGIPAPSEPLLCKFADGGQKKRQNQSKYTQNGRPWPREGEAGMALTYDPTAALQNGFYSSPYSLATNRMIPQTSITPFIAASPVSTYQVQSTSWTPHLPYIMQPTGAVITPTMDHPMSMQPTNIVGPLTQQMNHLSLGTAGTIQSQDRIMVLHQLLCQYMTAAPMQGTYIPQYTPVPPTAVSIETVAPSSQDSSGQQQQLAVDTPNEHAPAYSFQQSKP", "length": 422, "header": "tr|A0A9J7JR70-1|A0A9J7JR70_CRIGR Computationally mapped isoform of RNA-binding motif, single-stranded-interacting protein 3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Rbms3 PE=4 SV=1 CANONICAL=A0A8C2LKR6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JXQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKR6/entry#A0A9J7JXQ1-1", "sequence": { "sequence": "MGKRLDQPQMYPQYTYYCPQYLQTKQSYAPAPHPMAPPSPSTNSSSNSSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASLKANGVQAQMAKQQEQDPTNLYISNLPISMDEQELENMLKPFGHVISTRILRDANGVSRGVGFARMESTEKCEVVIQHFNGKYLKTPPGIPAPSEPLLCKFADGGQKKRQNQSKYTQNGRPWPREGEAGMALTYDPTAALQNGFYSSPYSLATNRMIPQTSITPFIAASPVSTYQGAVITPTMDHPMSMQPTNIVGPLTQQMNHLSLGTAGTYMTAAPMQGTYIPQYTPVPPTAVSIEGVVADTSPQTVAPSSQDSSGQQQQLAVDTPNEHAPAYSFQQSKP", "length": 398, "header": "tr|A0A9J7JXQ1-1|A0A9J7JXQ1_CRIGR Computationally mapped isoform of RNA-binding motif, single-stranded-interacting protein 3 isoform X7 OS=Cricetulus griseus OX=10029 GN=Rbms3 PE=4 SV=1 CANONICAL=A0A8C2LKR6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 382, "start_aa": "Thr", "end_pos": 382, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr382", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJE2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJE2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJE2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJE2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100774438", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774438", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1UHR1-1", "protein_name": "RNA binding motif single stranded interacting protein 3", "gene_name": "RBMS3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGKRLDQPQMYPQYTYYYPHYLQTKQSYAPAPHPMAPPSPSTNSSSNHSSSNSSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASLKANGVQAQMAKQQEQDPTNLYISNLPISMDEQELENMLKPFGHVISTRILRDANGVSRGVGFARMESTEKCEVVIQHFNGKYLKTPPGIPAPSEPLLCKFADGGQKKRQNQSKYTQNGRPWPREGEAGMALTYDPTAAIQNGFYSSPYSIATNRMIPQTSITPFIAAPPVSTYQVQSTSWMPHPPYVMQPTGAVITPTMDHPMSMQPANMMGPLTQQMNHLSLGTTGTIQSQDRIMILHQLLCQYMTAAAPMQGTYIPQYTPVPPTAVSIEGVVADTSPQTVAPSSQDTSGQQQQIAVDTSNEHASAYSYQQSKP", "length": 437 }, "evidence": [ { "id": "A0A8C2LKR6", "url": "https://omabrowser.org/oma/group/A0A8C2LKR6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6GKY7-1", "protein_name": "RNA binding motif, single stranded interacting protein 3", "gene_name": "Rbms3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEMDVEGVSPRPEPIPRSQGAGGACQAPPQPPQPQPQPQQQLAQDEVPSESAGAEDSDDPEARPNGERGESKSNATVRAYQSSKSRVTMSPGFSSQWSNSQPAWNTYSFPRASLHYQSHASYTYCTGHPVQSYAPAPHPMAPPSPSTNSSSNSSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASLKANGVQAQMAKQQEQDPTNLYISNLPISMDEQELENMLKPFGHVISTRILRDANGVSRGVGFARMESTEKCEVVIQHFNGKYLKTPPGIPAPSEPLLCKFADGGQKKRQSQNKHTQNGRPWPREGEAGMALTYDPTAALQNGFYSSPYSLATNRMIPQTSITPFIAASPVSTYQVQSTSWTPHLPYIMQPTGAVITPTMDHPMSMQPTNIVGPLTQQMNHLSLGTAGTIQSQDRIMVLHQLLCQYMTAAPMQGTYIPQYTPVPPTAVSIEGVVADTSPQTVAPSSQDSSGQQQQLAVDTPSEHAPAYSFQQSKP", "length": 536 }, "evidence": [ { "id": "A0A8C2LKR6", "url": "https://omabrowser.org/oma/group/A0A8C2LKR6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QGV3-1", "protein_name": "RNA-binding motif, single-stranded-interacting protein 3 isoform 2", "gene_name": "rbms3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGKRLEQQPMYPQYTYYYPHYLQTKQSYAPPPPPMAPPSPSTNSSSHSAAEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASLKASGVQAQMAKQQEQDPTNLYISNLPVSMDEQELENMLKPFGHVISTRILRDANGVSRGVGFARMESTEKCDVVIQHFNGKFLKTPPGVPAPTEPLLCKFADGGQKKRQSQSKYPQNGRPWPREGESGMALTYDPTAMQNGFYSSPYSISTNRMIAQTSITPFIAASPVSTYQVQSTSWMPHQQYVMQPTGAVITPTMDHTISMQPANMMGPLTQQMNHLSLGTTGTYMTAAAAPMQGTYIPQYTAVPASAVSVEGVVTDASPQSVPASSQDASGQQQALGVENTSDHAPTYSFQPAK", "length": 415 }, "evidence": [ { "id": "A0A8C2LKR6", "url": "https://omabrowser.org/oma/group/A0A8C2LKR6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6XE24-1", "protein_name": "RNA-binding motif, single-stranded-interacting protein 3", "gene_name": "RBMS3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGKRLDQPQMYPQYTYYYPHYLQTKQSYAPAPHPMAPPSPSTNSSSNNSSNNSSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASLKANGVQAQMAKQQEQDPTNLYISNLPISMDEQELENMLKPFGHVISTRILRDANGVSRGVGFARMESTEKCEVVIQHFNGKYLKTPPGIPAPSEPLLCKFADGGQKKRQNQSKYTQNGRPWPREGEAGMALTYDPTAAIQNGFYSSPYSIATNRMIPQTSITPFIAASPVSTYQVQSTSWMPHPPYVMQPTGAVITPTMDHPMSMQPANMMGPLTQQMNHLSLGTTGTIQSQDRIMILHQLLCQYMTAAAPMQGTYIPQYTPVPPTAVSIEGVVADTSPQTVAPSSQDTSGQQQQIAVDTSNEHAPAYSYQQSKP", "length": 437 }, "evidence": [ { "id": "A0A8C2LKR6", "url": "https://omabrowser.org/oma/group/A0A8C2LKR6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BWL5-1", "protein_name": "RNA-binding motif, single-stranded-interacting protein 3", "gene_name": "Rbms3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGKRLDQPQMYPQYTYYCPQYLQTKQSYAPAPHPMAPPSPSTNSSSNSSGEQLSKTNLYIRGLPPGTTDQDLIKLCQPYGKIVSTKAILDKNTNQCKGYGFVDFDSPAAAQKAVASLKANGVQAQMAKQQEQDPTNLYISNLPISMDEQELENMLKPFGHVISTRILRDANGVSRGVGFARMESTEKCEVVIQHFNGKYLKTPPGIPAPSEPLLCKFADGGQKKRQGQSKHTQNGRPWPREGEAGMALTYDPTAALQNGFYSSPYSLATNRMIPQTSITPFIAASPVSTYQVQSTSWTPHLPYIMQPTGAVITPAVDHPMSMQPTNIVGPLTQQMNHLSLGTAGTIQSQDRIMVLHQLLCQYMTAAPMQGTYIPQYTPVPPTAVSIEGVVADTSPQTVAPSSQDSSGQQQQLAVDTPSEHAPAYSFQQSKP", "length": 431 }, "evidence": [ { "id": "A0A8C2LKR6", "url": "https://omabrowser.org/oma/group/A0A8C2LKR6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LKR6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKR6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LKR6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKR6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" }, { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LKR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKR6" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 56, "end_pos": 129, "start_aa": "Thr", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 382 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 227, "end_pos": 229 }, { "start_pos": 43, "end_pos": 45 }, { "start_pos": 47, "end_pos": 49 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LJH3-1", "uniprot_ac": "A0A8C2LJH3", "uniprot_id": "A0A8C2LJH3_CRIGR", "mass": { "chemical_mass": 126246.0, "monoisotopic_mass": 126246.0 }, "refseq": { "ac": "XP_027250415", "name": "cartilage intermediate layer protein 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250415" }, "gene_names": [ { "name": "LOC103160703", "type": "recommended", "evidence": [ { "id": "A0A8C2LJH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJH3" } ] }, { "name": "LOC103160703", "type": "synonym", "evidence": [ { "id": "XP_027250415", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250415" } ] } ], "protein_names": [ { "name": "Cartilage intermediate layer protein 2 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A8C2LJH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJH3/entry#names_and_taxonomy" } ] }, { "name": "cartilage intermediate layer protein 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027250415", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250415" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027250415", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250415" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJH3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJH3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC103160703", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJH3", "locus": {} } ], "crossref": [ { "id": "103160703", "url": "https://www.ncbi.nlm.nih.gov/gene/103160703", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025155", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025155", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056255", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056255", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056256", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056256", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056257", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056257", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056258", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056258", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:103160703", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103160703", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LJH3", "url": "https://www.orthodb.org/?gene=A0A8C2LJH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15031", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15031", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15031:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15031:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13330", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13330", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23591", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23591", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23599", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23599", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23708", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23708", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23730", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23730", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027250415", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027250415", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LJH3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LJH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJH3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASPLPVLCLCIAAAHLAGARDATSTEERIEAARGLPGPDPGQPSPALEDWEEASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPASVGEQVHANPARGFWCLNREQPRGRRCSNYHVRFRCPLEAAWGPWGAWGLCSKSCGPGRRLRRRSCQSSSGDTCLGNPQEAQKCVRSRCPGCSSDTCRCPDHILLGSVVTPSGRPLPGARVFLKARPGTIATSDTHGTFLVPGVCAGGQTNVSAQMDGFSTGTALAHANSSNSAVVTIVLKELGKPYLVKHPESRVQEAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRRQHGSGSHLELRGLREDQAGEYHCKAWNEAGAVRSRAAQLTVLAPGQPACDPRPQEYLIKLPDDCGQPGGGPAYLDVGLCADTRCAGPADPGPSCGDTGSRCCSVLRLESRDIRCSGYVLPVKVVAECGCRKCLPRLGLVRGRVVAADSGEPLRFARILLGRAPIGFTSYQGDFTIQVPPVTDRLVVTFVDPTGEFVDSVRVLPFDPRGAGVYHEVRALRKAASVLLDAERGGAIPLGGAEGTAAPAPALGELVLPPGTFRHPDGRAYTGPVEARVTFVDPRDLASASAASSDLRFLDSSGEMAPLRTYGMFAVDLRAPGSAEQLHAARAAVRVDAEHVRMPGHAEALALWSLEPESGLWEREGAEQGGGGFRREEAAARRARREERAFLVGALTVRERRLFNLDVPERRRCFVKVRAYGTDRFAPAEQVQGVVVTLLNLEPAPGFAGNPRAWGRFDSAVTGPNGACVPAFCDAERPDAYTALVTATLGGEELEAAPSRPRATAAAVGVTQPYLERLGYQRTDHDDPALKRTGFRVNLARPRAGRESEAHGPMYPWRRLRDCEDAPVTHSHFRFSRVEADKYEYDVVPFREGAPASWTGDLLAWWPNPQEFRACFLKVRLQGPQEYMVRSHNAGGTHVGTRGRLYGLRDTRSVRHPERPGASAACVEFKCGGMLFDQRQVDRTLVTVTPQGSCRRVAVNALLQDYLARHPPTAPDDDPATFAMLAPLDALGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPRARPSLFQRLLENPESALGDIRREMGQANRDSRLAQTQAGNTDPFGLPPGQ", "length": 1167, "header": "tr|A0A8C2LJH3-1|A0A8C2LJH3_CRIGR Isoform 1 of Cartilage intermediate layer protein 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC103160703 PE=4 SV=1 CANONICAL=A0A8C2LJH3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LJH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJH3/entry#A0A8C2LJH3-1", "sequence": { "sequence": "MASPLPVLCLCIAAAHLAGARDATSTEERIEAARGLPGPDPGQPSPALEDWEEASEWTSWFNVDHPGGDGDFESLAAIRFYYGPARVCPRPLALEARTTDWALPASVGEQVHANPARGFWCLNREQPRGRRCSNYHVRFRCPLEAAWGPWGAWGLCSKSCGPGRRLRRRSCQSSSGDTCLGNPQEAQKCVRSRCPGCSSDTCRCPDHILLGSVVTPSGRPLPGARVFLKARPGTIATSDTHGTFLVPGVCAGGQTNVSAQMDGFSTGTALAHANSSNSAVVTIVLKELGKPYLVKHPESRVQEAGQNVTFCCKASGTPMPKKYSWFHNGTLLDRRQHGSGSHLELRGLREDQAGEYHCKAWNEAGAVRSRAAQLTVLAPGQPACDPRPQEYLIKLPDDCGQPGGGPAYLDVGLCADTRCAGPADPGPSCGDTGSRCCSVLRLESRDIRCSGYVLPVKVVAECGCRKCLPRLGLVRGRVVAADSGEPLRFARILLGRAPIGFTSYQGDFTIQVPPVTDRLVVTFVDPTGEFVDSVRVLPFDPRGAGVYHEVRALRKAASVLLDAERGGAIPLGGAEGTAAPAPALGELVLPPGTFRHPDGRAYTGPVEARVTFVDPRDLASASAASSDLRFLDSSGEMAPLRTYGMFAVDLRAPGSAEQLHAARAAVRVDAEHVRMPGHAEALALWSLEPESGLWEREGAEQGGGGFRREEAAARRARREERAFLVGALTVRERRLFNLDVPERRRCFVKVRAYGTDRFAPAEQVQGVVVTLLNLEPAPGFAGNPRAWGRFDSAVTGPNGACVPAFCDAERPDAYTALVTATLGGEELEAAPSRPRATAAAVGVTQPYLERLGYQRTDHDDPALKRTGFRVNLARPRAGRESEAHGPMYPWRRLRDCEDAPVTHSHFRFSRVEADKYEYDVVPFREGAPASWTGDLLAWWPNPQEFRACFLKVRLQGPQEYMVRSHNAGGTHVGTRGRLYGLRDTRSVRHPERPGASAACVEFKCGGMLFDQRQVDRTLVTVTPQGSCRRVAVNALLQDYLARHPPTAPDDDPATFAMLAPLDALGHNYGVYTVTDQSPRLAKEIAIGRCFDGSSDGFSREMKADAGTAVTFQCREPRARPSLFQRLLENPESALGDIRREMGQANRDSRLAQTQAGNTDPFGLPPGQ", "length": 1167, "header": "tr|A0A8C2LJH3-1|A0A8C2LJH3_CRIGR Isoform 1 of Cartilage intermediate layer protein 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC103160703 PE=4 SV=1 CANONICAL=A0A8C2LJH3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 215, "start_aa": "Thr", "end_pos": 215, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr215", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJH3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJH3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJH3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJH3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:103160703", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103160703", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJH3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJH3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 307, "end_pos": 309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LJH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJH3" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 291, "end_pos": 375, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 215 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 256, "end_pos": 258 }, { "start_pos": 274, "end_pos": 276 }, { "start_pos": 307, "end_pos": 309 }, { "start_pos": 328, "end_pos": 330 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { 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}, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LJI2-1", "uniprot_ac": "A0A8C2LJI2", "uniprot_id": "A0A8C2LJI2_CRIGR", "mass": { "chemical_mass": 5936.0, "monoisotopic_mass": 5936.0 }, "refseq": { "ac": "XP_016819199", "name": "IgA-inducing protein homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016819199" }, "gene_names": [ { "name": "Igip", "type": "recommended", "evidence": [ { "id": "A0A8C2LJI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJI2" } ] }, { "name": "Igip", "type": "synonym", "evidence": [ { "id": "XP_016819199", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016819199" } ] } ], "protein_names": [ { "name": "IgA-inducing protein homolog", "type": "synonym", "evidence": [ { "id": "XP_016819199", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016819199" }, { "id": "A0A8C2LJI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJI2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003617053.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_003614137.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003505339", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505339" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJL7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJL7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mterf2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJL7", "locus": {} } ], "crossref": [ { "id": "100761371", "url": "https://www.ncbi.nlm.nih.gov/gene/100761371", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003690", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003690", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038538", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038538", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761371", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761371", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LJL7", "url": "https://www.orthodb.org/?gene=A0A8C2LJL7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15437", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15437", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15437:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15437:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003505339", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505339", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LJL7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LJL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJL7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWELASAYSMSWRMLTGHQLCRLCLLRKPQPALKIKRSTCVTYEMDSQANKQSKRTVEKLQACSVDIMKICRLKAWVLLEDNTYVEEIANILKELGANKTVIASILERCPEAIVCSPVAVNAKKKLWQMVCKNEAELIRLIEQFPEPFFTVKDQENQKLNVQFFQELGLKNVVISRFLTTASSIFHNPVENNRRMIGVLQESYLNLGGSQANAKVWLLKLLSQNPFILLSSPTAVAQILQFLQGQGFTNSEVLQLLSKLKGFLFQLQPGSIQSSMSFTKAIFECTDHDLRQLVVNCPSLLCYPASILEERIQALLKEGITVTQIRESPMVLELTPQIVQYRIRKLNSLGYKIKDGHLASLNGTKKEFEANFSKMQAKQERPLFNPVASLHVEE", "length": 393, "header": "tr|A0A8C2LJL7-1|A0A8C2LJL7_CRIGR Isoform 1 of Transcription termination factor 2, mitochondrial OS=Cricetulus griseus OX=10029 GN=Mterf2 PE=3 SV=1 CANONICAL=A0A8C2LJL7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LJL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJL7/entry#A0A8C2LJL7-1", "sequence": { "sequence": "MWELASAYSMSWRMLTGHQLCRLCLLRKPQPALKIKRSTCVTYEMDSQANKQSKRTVEKLQACSVDIMKICRLKAWVLLEDNTYVEEIANILKELGANKTVIASILERCPEAIVCSPVAVNAKKKLWQMVCKNEAELIRLIEQFPEPFFTVKDQENQKLNVQFFQELGLKNVVISRFLTTASSIFHNPVENNRRMIGVLQESYLNLGGSQANAKVWLLKLLSQNPFILLSSPTAVAQILQFLQGQGFTNSEVLQLLSKLKGFLFQLQPGSIQSSMSFTKAIFECTDHDLRQLVVNCPSLLCYPASILEERIQALLKEGITVTQIRESPMVLELTPQIVQYRIRKLNSLGYKIKDGHLASLNGTKKEFEANFSKMQAKQERPLFNPVASLHVEE", "length": 393, "header": "tr|A0A8C2LJL7-1|A0A8C2LJL7_CRIGR Isoform 1 of Transcription termination factor 2, mitochondrial OS=Cricetulus griseus OX=10029 GN=Mterf2 PE=3 SV=1 CANONICAL=A0A8C2LJL7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJL7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJL7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJL7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJL7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761371", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761371", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "termination of mitochondrial transcription", "id": "GO:0006393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006393", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJL7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJL7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJL7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJL7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial nucleoid", "id": "GO:0042645", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042645", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJL7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJL7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" }, { "start_pos": 370, "end_pos": 372, "annotation": "n_glycosylation_sequon" }, { "start_pos": 98, "end_pos": 100, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 361, "end_pos": 363 }, { "start_pos": 370, "end_pos": 372 }, { "start_pos": 98, "end_pos": 100 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LJM3-1", "uniprot_ac": "A0A8C2LJM3", "uniprot_id": "A0A8C2LJM3_CRIGR", "mass": { "chemical_mass": 41750.0, "monoisotopic_mass": 41750.0 }, "refseq": { "ac": "XP_003499452", "name": "leucine-rich repeat-containing protein 28 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499452" }, "gene_names": [ { "name": "Lrrc28", "type": "recommended", "evidence": [ { "id": "A0A8C2LJM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJM3" } ] }, { "name": "Lrrc28", "type": "synonym", "evidence": [ { "id": "XP_003499452", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499452" } ] } ], "protein_names": [ { "name": "Leucine-rich repeat-containing protein 28 isoform X4", "type": "synonym", "evidence": [ { "id": "A0A8C2LJM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJM3/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat-containing protein 28 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003499452", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499452" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 333 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613734.1) and transcript sequence (IACG01046443.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003499452.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003499452", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499452" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJM3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJM3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Lrrc28", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJM3", "locus": {} } ], "crossref": [ { "id": "cd01213", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01213", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100769663", "url": "https://www.ncbi.nlm.nih.gov/gene/100769663", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013625", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013625", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033929", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033929", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051484", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051484", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055414", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055414", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769663", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769663", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LJM3", "url": "https://www.orthodb.org/?gene=A0A8C2LJM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45734", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45734", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45734:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45734:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08416", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08416", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003499452", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003499452", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LJM3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LJM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FN58", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FN58-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FN58-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHR0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JHR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JHR0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASELCKTISVARLEKHKNLFLNYRNLHHFPLELLKDEGLQHLERLYMKRNSLTTLPENLAQKLPNLVELYLHSNNIVVVPEAIGSLVKLQCLDLSDNALEIVCPEIGRLRALRHLRLANNQLQFLPPEVGDLKELQTLDISTNRLLALPERLHLCLSLQYLTVDRNRLWCVPRHLCQLPSLNELSMAGNRLAFLPLDLGRSRELQYVYVDNNIHLKGLPSYLYNKVIGCSGCGVTIQVSEVKLLSFSSGQLTVFLPAEVKAIGTQDDHVLPLQELAMRSLYHTYHKFPKDLNFLSPISLPRSLLELLHCPLGHCHRCSEPMFTFVYPKLFPLRETPMAGLHQGRTTVGFVAYCCSTQCLQTFDLLS", "length": 367, "header": "tr|A0A8C2LJM3-1|A0A8C2LJM3_CRIGR Isoform 1 of Leucine-rich repeat-containing protein 28 isoform X4 OS=Cricetulus griseus OX=10029 GN=Lrrc28 PE=4 SV=1 CANONICAL=A0A8C2LJM3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LJM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJM3/entry#A0A8C2LJM3-1", "sequence": { "sequence": 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"MASELCKTISVARLEKHKNLFLNYRNLHHFPLELLKDEGLQHLERLYMKRNSLTTLPENLAQKLPNLVELYLHSNNIVVVPEAIGSLVKLQCLDLSDNALEIVCPEIGRLRALRHLRLANNQLQFLPPDLGRSRELQYVYVDNNIHLKGLPSYLYNKVIGCSGCGVTIQVSEVKLLSFSSGQLTVFLPAEVKAIGTQDDHVLPLQELAMRSLYHTYHKFPKDLNFLSPISLPRSLLELLHCPLGHCHRCSEPMFTFVYPKLFPLRETPMAGLHQGRTTVGFVAYCCSTQCLQTFDLLS", "length": 298, "header": "tr|A0A9J7FN58-1|A0A9J7FN58_CRIGR Computationally mapped isoform of Leucine-rich repeat-containing protein 28 isoform X6 OS=Cricetulus griseus OX=10029 GN=Lrrc28 PE=4 SV=1 CANONICAL=A0A8C2LJM3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JHR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJM3/entry#A0A9J7JHR0-1", "sequence": { "sequence": 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Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027256148", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256148" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJR2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJR2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100765849", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJR2", "locus": {} } ], "crossref": [ { "id": "cd00095", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00095", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100765849", "url": "https://www.ncbi.nlm.nih.gov/gene/100765849", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000471", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000471", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765849", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765849", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LJR2", "url": "https://www.orthodb.org/?gene=A0A8C2LJR2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11691", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11691", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11691:SF60", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11691:SF60", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00143", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00143", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027256148", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256148", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LJR2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LJR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJR2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARLCAFLLALVVMSYWSTCCLGCDLPQTHNIRNKRALTLLAQMRRLSPLSCLKDRKDFAFPLEKVDAQHIQKTQAIPVLQELTQQVLILFSSKGSSASWETTLLDTFCTGLHQQLSDLRACLMQQLGVQEPPLSQEDSLVAVRKYFHRITAYLREKNHSPCAWEVVRAEVWRALSSSANLLARLSEEKE", "length": 190, "header": "tr|A0A8C2LJR2-1|A0A8C2LJR2_CRIGR Isoform 1 of Interferon alpha-12 OS=Cricetulus griseus OX=10029 GN=LOC100765849 PE=3 SV=1 CANONICAL=A0A8C2LJR2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LJR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJR2/entry#A0A8C2LJR2-1", "sequence": { "sequence": "MARLCAFLLALVVMSYWSTCCLGCDLPQTHNIRNKRALTLLAQMRRLSPLSCLKDRKDFAFPLEKVDAQHIQKTQAIPVLQELTQQVLILFSSKGSSASWETTLLDTFCTGLHQQLSDLRACLMQQLGVQEPPLSQEDSLVAVRKYFHRITAYLREKNHSPCAWEVVRAEVWRALSSSANLLARLSEEKE", "length": 190, "header": "tr|A0A8C2LJR2-1|A0A8C2LJR2_CRIGR Isoform 1 of Interferon alpha-12 OS=Cricetulus griseus OX=10029 GN=LOC100765849 PE=3 SV=1 CANONICAL=A0A8C2LJR2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027274266", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274266" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJS3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJS3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100772859", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJS3", "locus": {} } ], "crossref": [ { "id": "100772859", "url": "https://www.ncbi.nlm.nih.gov/gene/100772859", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006862", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006862", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016662", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016662", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042490", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042490", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772859", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772859", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LJS3", "url": "https://www.orthodb.org/?gene=A0A8C2LJS3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10824", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10824", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10824:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10824:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04775", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04775", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08840", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08840", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027274266", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274266", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LJS3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LJS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJS3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVASPLAVLRTSRLCQWGWKSRARLSGSLPFGRGGWTTWAPARTNATLSLEPAGRSCWDEPLGISVHGLAPEQPVTLRAALRDEKGALFRAHARYRADDHGGLDLARAPALGGSFAGIEPMGLLWALEPERPFWRLIKRDVQTPFVVELEVLDGHEPDGGRLLTRAVHERHFMAPGVRRVPVREGRVRATLFLPPEPGPYPGILDLFGVGGGLLEYRASLLAGKGFAVMALAYYNYDDLPKGMDTMRMEYFEEAVNYLLSHPEVKGPGIGLLGISKGGELGLAMASFLKGIKAAVVINGSVAAVGNTIYYKDETIPPVSLLRNRVKMTKDGLLDVVEGLQSPLVEEKSFIPVERSDTAFLLLVGQDDHNWKSEFYANEISKRLEAHGKGKPQIICYPEAGHYIEPPYFPLYKAGMHLLVGANITFGGEPKPHAVAQVDAWQQLQTFLHKHLGGKS", "length": 455, "header": "tr|A0A8C2LJS3-1|A0A8C2LJS3_CRIGR Isoform 1 of Acyl-coenzyme A thioesterase 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100772859 PE=3 SV=1 CANONICAL=A0A8C2LJS3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LJS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJS3/entry#A0A8C2LJS3-1", "sequence": { "sequence": "MVASPLAVLRTSRLCQWGWKSRARLSGSLPFGRGGWTTWAPARTNATLSLEPAGRSCWDEPLGISVHGLAPEQPVTLRAALRDEKGALFRAHARYRADDHGGLDLARAPALGGSFAGIEPMGLLWALEPERPFWRLIKRDVQTPFVVELEVLDGHEPDGGRLLTRAVHERHFMAPGVRRVPVREGRVRATLFLPPEPGPYPGILDLFGVGGGLLEYRASLLAGKGFAVMALAYYNYDDLPKGMDTMRMEYFEEAVNYLLSHPEVKGPGIGLLGISKGGELGLAMASFLKGIKAAVVINGSVAAVGNTIYYKDETIPPVSLLRNRVKMTKDGLLDVVEGLQSPLVEEKSFIPVERSDTAFLLLVGQDDHNWKSEFYANEISKRLEAHGKGKPQIICYPEAGHYIEPPYFPLYKAGMHLLVGANITFGGEPKPHAVAQVDAWQQLQTFLHKHLGGKS", "length": 455, "header": "tr|A0A8C2LJS3-1|A0A8C2LJS3_CRIGR Isoform 1 of Acyl-coenzyme A thioesterase 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100772859 PE=3 SV=1 CANONICAL=A0A8C2LJS3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJS3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJS3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100772859", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772859", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "fatty acid metabolic process", "id": "GO:0006631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006631", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJS3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJS3" } ], "pmid": "" }, { "name": "acyl-CoA metabolic process", "id": "GO:0006637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006637", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJS3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJS3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "fatty acyl-CoA hydrolase activity", "id": "GO:0047617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047617", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJS3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJS3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 422, "end_pos": 424, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LJS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJS3" }, { "id": "PF04775", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04775" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase", "eco_id": "ECO_0000259", "start_pos": 59, "end_pos": 184, "start_aa": "Asp", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2LJS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJS3" }, { "id": "PF08840", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08840" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BAAT/Acyl-CoA thioester hydrolase C-terminal", "eco_id": "ECO_0000259", "start_pos": 247, "end_pos": 452, "start_aa": "Arg", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 298, "end_pos": 300 }, { "start_pos": 422, "end_pos": 424 }, { "start_pos": 45, "end_pos": 47 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LJX0-1", "uniprot_ac": "A0A8C2LJX0", "uniprot_id": "A0A8C2LJX0_CRIGR", "mass": { "chemical_mass": 7144.0, "monoisotopic_mass": 7144.0 }, "refseq": { "ac": "XP_003512727", "name": "beta-defensin 4-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512727" }, "gene_names": [ { "name": "LOC100767221", "type": "recommended", "evidence": [ { "id": "A0A8C2LJX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJX0" } ] }, { "name": "LOC100767221", "type": "synonym", "evidence": [ { "id": "XP_003512727", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512727" } ] } ], "protein_names": [ { "name": "Beta-defensin 4-like", "type": "synonym", "evidence": [ { "id": "A0A8C2LJX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJX0/entry#names_and_taxonomy" } ] }, { "name": "beta-defensin 4-like", "type": "synonym", "evidence": [ { "id": "XP_003512727", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512727" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615540.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003512727", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512727" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJX0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJX0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100767221", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJX0", "locus": {} } ], "crossref": [ { "id": "100767221", "url": "https://www.ncbi.nlm.nih.gov/gene/100767221", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006080", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006080", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767221", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767221", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PGTKCCR", "url": "https://omabrowser.org/oma/group/PGTKCCR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LJX0", "url": "https://www.orthodb.org/?gene=A0A8C2LJX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20515", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20515", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20515:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20515:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00711", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00711", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003512727", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512727", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LJX0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LJX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJX0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRIHYLLLTFLLVLLSPFSAFTQRIKNPVTCLTNGGICWGACRGNFRQIGTCGIPKVRCCKRR", "length": 63, "header": "tr|A0A8C2LJX0-1|A0A8C2LJX0_CRIGR Isoform 1 of Beta-defensin 4-like OS=Cricetulus griseus OX=10029 GN=LOC100767221 PE=4 SV=1 CANONICAL=A0A8C2LJX0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LJX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJX0/entry#A0A8C2LJX0-1", "sequence": { "sequence": "MRIHYLLLTFLLVLLSPFSAFTQRIKNPVTCLTNGGICWGACRGNFRQIGTCGIPKVRCCKRR", "length": 63, "header": "tr|A0A8C2LJX0-1|A0A8C2LJX0_CRIGR Isoform 1 of Beta-defensin 4-like OS=Cricetulus griseus OX=10029 GN=LOC100767221 PE=4 SV=1 CANONICAL=A0A8C2LJX0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJX0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJX0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJX0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJX0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767221", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767221", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O02775-1", "protein_name": "Enteric beta-defensin", "gene_name": "EBD", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLTLLFLVLSAGSGFTQGISNPLSCRLNRGICVPIRCPGNLRQIGTCFTPSVKCCRWR", "length": 64 }, "evidence": [ { "id": "A0A8C2LJX0", "url": "https://omabrowser.org/oma/group/A0A8C2LJX0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O15263-1", "protein_name": "Defensin beta 4A", "gene_name": "DEFB4B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRVLYLLFSFLFIFLMPLPGVFGGIGDPVTCLKSGAICHPVFCPRRYKQIGTCGLPGTKCCKKP", "length": 64 }, "evidence": [ { "id": "A0A8C2LJX0", "url": "https://omabrowser.org/oma/group/A0A8C2LJX0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O88514-1", "protein_name": "Beta-defensin 4", "gene_name": "Defb4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRIHYLLFSFLLVLLSPLSAFTQSINNPITCLTKGGVCWGPCTGGFRQIGTCGLPRVRCCKKK", "length": 63 }, "evidence": [ { "id": "A0A8C2LJX0", "url": "https://omabrowser.org/oma/group/A0A8C2LJX0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9WTL0-1", "protein_name": "Beta-defensin 3", "gene_name": "Defb3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRIHYLLFAFLLVLLSPPAAFSKKINNPVSCLRKGGRCWNRCIGNTRQIGSCGVPFLKCCKRK", "length": 63 }, "evidence": [ { "id": "A0A8C2LJX0", "url": "https://omabrowser.org/oma/group/A0A8C2LJX0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJX0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJX0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "chemoattractant activity", "id": "GO:0042056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042056", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJX0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJX0" } ], "pmid": "" }, { "name": "CCR6 chemokine receptor binding", "id": "GO:0031731", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031731", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJX0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJX0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell chemotaxis", "id": "GO:0060326", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060326", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJX0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJX0" } ], "pmid": "" }, { "name": "defense response to bacterium", "id": "GO:0042742", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042742", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJX0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJX0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LJX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJX0" }, { "id": "SM00048", 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"XP_027266675", "name": "proton-coupled amino acid transporter 4 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266675" }, "gene_names": [ { "name": "Slc36a4", "type": "recommended", "evidence": [ { "id": "A0A8C2LJZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJZ4" } ] }, { "name": "Slc36a4", "type": "synonym", "evidence": [ { "id": "XP_027266675", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266675" } ] } ], "protein_names": [ { "name": "Proton-coupled amino acid transporter 4 isoform X3", "type": "synonym", "evidence": [ { "id": "A0A8C2LJZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJZ4/entry#names_and_taxonomy" } ] }, { "name": "proton-coupled amino acid transporter 4 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027266675", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266675" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027266675", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266675" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJZ4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Slc36a4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJZ4", "locus": {} } ], "crossref": [ { "id": "100752115", "url": "https://www.ncbi.nlm.nih.gov/gene/100752115", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752115", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752115", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LJZ4", "url": "https://www.orthodb.org/?gene=A0A8C2LJZ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22950", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22950", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22950:SF190", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22950:SF190", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01490", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01490", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027266675", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266675", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LJZ4", "url": 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"MEAPAPAEAVGCEELDMDVMRPLINEQNFDGTSDEEPEQTLLPVQKHYQLDGQHGISFVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCQRFKKSTLGYSDTVSFAMEASPWSCLQRQAAWGRSVVDFFLVITQLGFCSVYIVFLAENVKQVHEGFLESTVFVSNSTDPSHACERRSVDLRVYMLCFLPFIILLVFIRELKNLFILSFLANISMAASLVIIYQYVVRNMPDPYNLPIVAGWKKYPLFFGTAVFAFEGIGVVLPLENQMKESKRFPQALNIGMAVVTVLYVSLATLGYMCFRDEIKGSITLNLPQDMWLYRSVKILYSFGIFVTYSIQFYVPAEIIIPGVTARLHAKWKRICEFGIRSFLVSITCAGAVLIPRLDIVISFVGAVSSSTLALILPPIVEILTFSKEHYNIWMVLKNISIAFTGVVGFLLGTYVTVEEILYPTTVAVAGAPQGLSLNVNSTCFASGLK", "length": 501, "header": "tr|A0A8C2LJZ4-1|A0A8C2LJZ4_CRIGR Isoform 1 of Proton-coupled amino acid transporter 4 isoform X3 OS=Cricetulus griseus OX=10029 GN=Slc36a4 PE=4 SV=1 CANONICAL=A0A8C2LJZ4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LJZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJZ4/entry#A0A8C2LJZ4-1", "sequence": { "sequence": "MEAPAPAEAVGCEELDMDVMRPLINEQNFDGTSDEEPEQTLLPVQKHYQLDGQHGISFVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCQRFKKSTLGYSDTVSFAMEASPWSCLQRQAAWGRSVVDFFLVITQLGFCSVYIVFLAENVKQVHEGFLESTVFVSNSTDPSHACERRSVDLRVYMLCFLPFIILLVFIRELKNLFILSFLANISMAASLVIIYQYVVRNMPDPYNLPIVAGWKKYPLFFGTAVFAFEGIGVVLPLENQMKESKRFPQALNIGMAVVTVLYVSLATLGYMCFRDEIKGSITLNLPQDMWLYRSVKILYSFGIFVTYSIQFYVPAEIIIPGVTARLHAKWKRICEFGIRSFLVSITCAGAVLIPRLDIVISFVGAVSSSTLALILPPIVEILTFSKEHYNIWMVLKNISIAFTGVVGFLLGTYVTVEEILYPTTVAVAGAPQGLSLNVNSTCFASGLK", "length": 501, "header": "tr|A0A8C2LJZ4-1|A0A8C2LJZ4_CRIGR Isoform 1 of Proton-coupled amino acid transporter 4 isoform X3 OS=Cricetulus griseus OX=10029 GN=Slc36a4 PE=4 SV=1 CANONICAL=A0A8C2LJZ4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FRY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJZ4/entry#A0A9J7FRY0-1", "sequence": { "sequence": "MEASPWSCLQRQAAWGRSVVDFFLVITQLGFCSVYIVFLAENVKQVHEGFLESTVFVSNSTDPSHACERRSVDLRVYMLCFLPFIILLVFIRELKNLFILSFLANISMAASLVIIYQYVVRNMPDPYNLPIVAGWKKYPLFFGTAVFAFEGIGVVLPLENQMKESKRFPQALNIGMAVVTVLYVSLATLGYMCFRDEIKGSITLNLPQDMWLYRSVKILYSFGIFVTYSIQFYVPAEIIIPGVTARLHAKWKRICEFGIRSFLVSITCAGAVLIPRLDIVISFVGAVSSSTLALILPPIVEILTFSKEHYNIWMVLKNISIAFTGVVGFLLGTYVTVEEILYPTTVAVAGAPQGLSLNVNSTCFASGLK", "length": 369, "header": "tr|A0A9J7FRY0-1|A0A9J7FRY0_CRIGR Computationally mapped isoform of Proton-coupled amino acid transporter 4 isoform X5 OS=Cricetulus griseus OX=10029 GN=Slc36a4 PE=4 SV=1 CANONICAL=A0A8C2LJZ4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JJN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJZ4/entry#A0A9J7JJN4-1", "sequence": { "sequence": "MEAPAPAEAVGCEELDMDVMRPLINEQNFDGTSDEEPEQTLLPVQKHYQLDGQHGISFVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCQRFKKSTLGYSDTVSFAMEASPWSCLQRQAAWGRSVVDFFLVITQLGFCSVYIVFLAENVKQVHEGFLESTVFVSNSTDPSHACERRSVDLRVYMLCFLPFIILLVFIRELKNLFILSFLANISMAASLVIIYQYVVRNMPDPYNLPIVAGWKKYPLFFGTAVFAFEGIGVVLPLENQMKESKRFPQALNIGMAVVTVLYVSLATLGYMCFRDEIKGSITLNLPQDMWLYRSVKILYSFGIFVTYSIQFYVPAEIIIPGVTARLHAKWKRICEFGIRSFLVLEQFSFLA", "length": 404, "header": "tr|A0A9J7JJN4-1|A0A9J7JJN4_CRIGR Computationally mapped isoform of Proton-coupled amino acid transporter 4 isoform X4 OS=Cricetulus griseus OX=10029 GN=Slc36a4 PE=4 SV=1 CANONICAL=A0A8C2LJZ4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJZ4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJZ4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752115", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752115", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "L-alanine transmembrane transporter activity", "id": "GO:0015180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015180", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LJZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LJZ4" } ], "pmid": "" }, { "name": "L-proline transmembrane transporter activity", "id": "GO:0015193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015193", "evidence": 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automated computational analysis. This record is derived from a genomic sequence (NW_003613580.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027253714", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253714" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LK50", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK50" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dym", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK50", "locus": {} } ], "crossref": [ { "id": "100764371", "url": "https://www.ncbi.nlm.nih.gov/gene/100764371", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019142", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019142", "database": "InterPro", "categories": [ "Protein Classification" ] }, 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"MGANSSSISDLPKNEYLKKLSGTESISENDPFWNQLFSFSFPAPTSSTELKLLEEATVSVCKSLVENNPRTGNLGALTKVFLSRTRELRLSAECQNHIFIWQTHNALFIICCLLKVFICEMSEEELQLHFMYEEKSPGSYSSHSEDLLEELLCSLVQLITDTPLLDITYEISVEAISAMVVFLSCQLFHKEVLRQSISHKYLMQGPCLPYTSKLVKTLLYNFIRQEKPPPPGTHVFPPQSDGGGLLYGLASGVATGLWTVFTLGGASSKAATSPELTSPLANQSLLLLLVLVNLTDAPDTPNPYRQAVTSFKNTQDSSPFPSSIPHAFQINFNSLYTALCEQQTSDQATLLLYTLLHQNSNVRTYMLARTDMENLVLPILEILYHVEERNSHHVYMALIILLILTEDDGFNRSIHEVILKNITWYSERVLTEISLGSLLILVVIRTIQYNMTRTRDKYLHTNCLAALANMSAQFRSLHQYAAQRIISLFSLLSKKHNKVLEQATQSLRGSLSSSDVPLPDYAQDLSVIEEVIRMMLEIINSCLTNSLHHNPNLVYALLYKRDLFEQFRTHPSFQDIMQNIDLVISFFSSRLLQAGAELSVERVLEIIKQGVVALPKDRLKKFPELKFKYVEEEQPEEFFIPYVWSLVYNSAVGLYWNPQDIQLFAMDSD", "length": 669, "header": "tr|A0A8C2LK50-1|A0A8C2LK50_CRIGR Isoform 1 of Dymeclin OS=Cricetulus griseus OX=10029 GN=Dym PE=3 SV=1 CANONICAL=A0A8C2LK50-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JUS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK50/entry#A0A9J7JUS1-1", "sequence": { "sequence": "MGANSSSISDLPKNEYLKKLSGTESISENDPFWNQLFSFSFPAPTSSTELKLLEEATVSVCKSLVENNPRTGNLGALTKVFLSRTRELRLSAECQNHIFIWQTHNALFIICCLLKVFICEMSEEELQLHFMYEEKSPGSYSSHSEDLLEELLCSLVQLITDTPLLDITYEISVEAISAMVVFLSCQLFHKEVLRQSISHKYLMQGPCLPYTSKLVKTLLYNFIRQEKPPPPGTHVFPPQSDGGGLLYGLASGVATGLWTVFTLGGASSKAATSPELTSPLANQSLLLLLVLVNLTDAPDTPNPYRQAVTSFKNTQDSSPFPSSIPHAFQINFNSLYTALCEQQTSDQATLLLYTLLHQNSNVRTYMLARTDMENLVLPILEILYHVEERNSHHVYMALIILLILTEDDGFNRSIHEVILKNITWYSERVLTEISLGSLLILVVIRTIQYNMTRTRDKYLHTNCLAALANMSAQFRSLHQYAAQRIISLFSLLSKKHNKVLEQATQSLRGSLSSSDVPLPDYAQDLSVIEEVIRMMLEIINSCLTNSLHHNPNLVYALLYKRDLFEQFRTHPSFQDIMQNIDLVISFFSSRLLQAGAELSVERVLEIIKQGVVALPKDRLKVFLLFDGVGTK", "length": 631, "header": "tr|A0A9J7JUS1-1|A0A9J7JUS1_CRIGR Computationally mapped isoform of Dymeclin OS=Cricetulus griseus OX=10029 GN=Dym PE=3 SV=1 CANONICAL=A0A8C2LK50-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LK50", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK50" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"evidence": [ { "database": "UniProtKB", "id": "A0A8C2LK50", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LK50" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 293, "end_pos": 295, "annotation": "n_glycosylation_sequon" }, { "start_pos": 411, "end_pos": 413, "annotation": "n_glycosylation_sequon" }, { "start_pos": 421, "end_pos": 423, "annotation": "n_glycosylation_sequon" }, { "start_pos": 450, "end_pos": 452, "annotation": "n_glycosylation_sequon" }, { "start_pos": 469, "end_pos": 471, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 282, "end_pos": 284 }, { "start_pos": 293, "end_pos": 295 }, { "start_pos": 411, "end_pos": 413 }, { "start_pos": 421, "end_pos": 423 }, { "start_pos": 450, "end_pos": 452 }, { "start_pos": 469, "end_pos": 471 }, { "start_pos": 4, "end_pos": 6 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { 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"count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LKD9-1", "uniprot_ac": "A0A8C2LKD9", "uniprot_id": "A0A8C2LKD9_CRIGR", "mass": { "chemical_mass": 15164.0, "monoisotopic_mass": 15164.0 }, "refseq": { "ac": "XP_003513749", "name": "cysteine-rich tail protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003513749" }, "gene_names": [ { "name": "Cysrt1", "type": "recommended", "evidence": [ { "id": "A0A8C2LKD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKD9" } ] }, { "name": "Cysrt1", "type": "synonym", "evidence": [ { "id": "XP_003513749", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003513749" } ] } ], "protein_names": [ { "name": "Cysteine-rich tail protein 1", "type": "synonym", "evidence": [ { "id": "A0A8C2LKD9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKD9/entry#names_and_taxonomy" } ] }, { "name": "cysteine-rich tail protein 1", "type": "synonym", "evidence": [ { "id": "XP_003513749", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003513749" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616080.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003513749", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003513749" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LKD9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKD9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cysrt1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKD9", "locus": {} } ], "crossref": [ { "id": "100772606", "url": "https://www.ncbi.nlm.nih.gov/gene/100772606", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772606", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772606", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CHRCCCV", "url": "https://omabrowser.org/oma/group/CHRCCCV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LKD9", "url": "https://www.orthodb.org/?gene=A0A8C2LKD9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR37879", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37879", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37879:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37879:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10631", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10631", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003513749", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003513749", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LKD9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKD9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LKD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKD9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPHEILTKNPYAHISIPRAHLRSDLGQQLEEVPSSSSSSETQPLPSGTCVPEPVGILQPTEAPGPKGIKGIKGTPEQSQQTWQSPCNPYSSGQRPSGLTYAGLPPVGRGDDIAHNCCCFPCCSCCHCPRFCRCHSCCCVVS", "length": 142, "header": "tr|A0A8C2LKD9-1|A0A8C2LKD9_CRIGR Isoform 1 of Cysteine-rich tail protein 1 OS=Cricetulus griseus OX=10029 GN=Cysrt1 PE=4 SV=1 CANONICAL=A0A8C2LKD9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LKD9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKD9/entry#A0A8C2LKD9-1", "sequence": { "sequence": "MDPHEILTKNPYAHISIPRAHLRSDLGQQLEEVPSSSSSSETQPLPSGTCVPEPVGILQPTEAPGPKGIKGIKGTPEQSQQTWQSPCNPYSSGQRPSGLTYAGLPPVGRGDDIAHNCCCFPCCSCCHCPRFCRCHSCCCVVS", "length": 142, "header": "tr|A0A8C2LKD9-1|A0A8C2LKD9_CRIGR Isoform 1 of Cysteine-rich tail protein 1 OS=Cricetulus griseus OX=10029 GN=Cysrt1 PE=4 SV=1 CANONICAL=A0A8C2LKD9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LKD9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKD9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LKD9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKD9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100772606", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772606", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0JNN6-1", "protein_name": "Cysteine-rich tail protein 1", "gene_name": "CYSRT1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDPHETLVKNPYAHISIPRAHLRPELGQQRKAGPSSAESRPLPVRSCTLEPLEEAPGPKGTKGRPASQQPCKPCGSGQRPAGLAYAGPPPAQRGDDIAHHCWCCPCCSCCHCPRFCRCHSCCCVVS", "length": 126 }, "evidence": [ { "id": "A0A8C2LKD9", "url": "https://omabrowser.org/oma/group/A0A8C2LKD9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D4ADR7-1", "protein_name": "Cysteine rich tail 1", "gene_name": "Cysrt1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPHEMVVKNPYVHLSIPRAHLRSDSGQQSEEVPSSSSSSETQPLPPGACAPEPVGLLHTVEAPGPKAIKGAKGEQCQQTWQSPCNPYSSGQRPSGLTYAGLPPVGRGDDIAHHCCCCPCCSCCHCPRFCRCHSCCCVVS", "length": 140 }, "evidence": [ { "id": "A0A8C2LKD9", "url": "https://omabrowser.org/oma/group/A0A8C2LKD9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RVW1-1", "protein_name": "Cysteine rich tail 1", "gene_name": "CYSRT1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPQEMVVKNPFAHISIPRAHLRPELGQQLEVAPFCPESQALPGGSCTLEPTEENTGPKGAKGAAPFQGQQAWQQPSNPYGSGPRPSGLTYAGLPPIGRGDDIAHHCCCCPCCSCCHCPRFCRCHSCCCVIS", "length": 132 }, "evidence": [ { "id": "A0A8C2LKD9", "url": "https://omabrowser.org/oma/group/A0A8C2LKD9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035303090", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303090" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LKG0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKG0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC118239120", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKG0", "locus": {} } ], "crossref": [ { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "118239120", "url": "https://www.ncbi.nlm.nih.gov/gene/118239120", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:118239120", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:118239120", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WDEGCAQ", "url": "https://omabrowser.org/oma/group/WDEGCAQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LKG0", "url": "https://www.orthodb.org/?gene=A0A8C2LKG0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24253", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24253", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24253:SF144", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24253:SF144", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035303090", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035303090", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LKG0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LKG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKG0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLKPLLLALPVLATLLQAAPRPSEQRVGIVGGQEASESKWPWQVSLRLKFSYWIHFCGGSLIHPQWVLTAAHCVGPHIQSPELFRVQLREQHLYYQDQLLPVNRIIVHPNYYSVEGGADIALLELEDPVNVSSHVQPISLPPAMETFPSGTSCWVTGWGDIDNGESLPPPYPLKQVKVPIVENSLCDRKYHTGLSTGDNVFIVHDDMLCAGNTGRDSCQGDSGGPLVCKVKGAWLQAGVVSWGEGCAEANHPGIYTRVTYYLEWIYHYVPEN", "length": 272, "header": "tr|A0A8C2LKG0-1|A0A8C2LKG0_CRIGR Isoform 1 of Tryptase beta-2-like OS=Cricetulus griseus OX=10029 GN=LOC118239120 PE=4 SV=1 CANONICAL=A0A8C2LKG0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LKG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKG0/entry#A0A8C2LKG0-1", "sequence": { "sequence": "MLKPLLLALPVLATLLQAAPRPSEQRVGIVGGQEASESKWPWQVSLRLKFSYWIHFCGGSLIHPQWVLTAAHCVGPHIQSPELFRVQLREQHLYYQDQLLPVNRIIVHPNYYSVEGGADIALLELEDPVNVSSHVQPISLPPAMETFPSGTSCWVTGWGDIDNGESLPPPYPLKQVKVPIVENSLCDRKYHTGLSTGDNVFIVHDDMLCAGNTGRDSCQGDSGGPLVCKVKGAWLQAGVVSWGEGCAEANHPGIYTRVTYYLEWIYHYVPEN", "length": 272, "header": "tr|A0A8C2LKG0-1|A0A8C2LKG0_CRIGR Isoform 1 of Tryptase beta-2-like OS=Cricetulus griseus OX=10029 GN=LOC118239120 PE=4 SV=1 CANONICAL=A0A8C2LKG0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LKG0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKG0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:118239120", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:118239120", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P21845-1", "protein_name": "Tryptase beta-2", "gene_name": "Tpsb2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLKRRLLLLWALSLLASLVYSAPRPANQRVGIVGGHEASESKWPWQVSLRFKLNYWIHFCGGSLIHPQWVLTAAHCVGPHIKSPQLFRVQLREQYLYYGDQLLSLNRIVVHPHYYTAEGGADVALLELEVPVNVSTHIHPISLPPASETFPPGTSCWVTGWGDIDNDEPLPPPYPLKQVKVPIVENSLCDRKYHTGLYTGDDFPIVHDGMLCAGNTRRDSCQGDSGGPLVCKVKGTWLQAGVVSWGEGCAQPNKPGIYTRVTYYLDWIHRYVPEHS", "length": 276 }, "evidence": [ { "id": "A0A8C2LKG0", "url": 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"https://www.ncbi.nlm.nih.gov/protein/XP_003510284" } ] } ], "protein_names": [ { "name": "Lymphocyte-specific protein 1", "type": "synonym", "evidence": [ { "id": "A0A8C2LKQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKQ8/entry#names_and_taxonomy" } ] }, { "name": "lymphocyte-specific protein 1", "type": "synonym", "evidence": [ { "id": "XP_003510284", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510284" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614851.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003510284", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510284" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LKQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKQ8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Lsp1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKQ8", "locus": {} } ], "crossref": [ { "id": "100767209", "url": "https://www.ncbi.nlm.nih.gov/gene/100767209", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002211", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002211", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767209", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767209", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TRIDDKM", "url": "https://omabrowser.org/oma/group/TRIDDKM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LKQ8", "url": "https://www.orthodb.org/?gene=A0A8C2LKQ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18949", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18949", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18949:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18949:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02029", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02029", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003510284", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510284", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LKQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LKQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNGPALLRRNASKRGLEKLLRLTTQWREEDKEEAAREQRQRERERQLQDQDQDKVEDEGDHSLEQPEQQALLSLKSSELDEDEGFGDWSQKMEQRQQCWENEGTAEGTEPSQNESPEETQAEDRSQQVKVHLEELNLSQEEPSPEDTVGSCEEAEENLASHQARTPSPLALEETVEPSSPPLSPTTTLADRTESLNRSIKKSNSVKKSQPTLPISTIDERLQQYTQATESAGRTPKLSRQPSIELPSMAVASTKTRWETGEVQTQSASKTPSCQDIVAGDMSKKSLWEQKGSSKISSTIKSTPSGKRYKFVATGHGKYEKVLVDEGSAP", "length": 329, "header": "tr|A0A8C2LKQ8-1|A0A8C2LKQ8_CRIGR Isoform 1 of Lymphocyte-specific protein 1 OS=Cricetulus griseus OX=10029 GN=Lsp1 PE=4 SV=1 CANONICAL=A0A8C2LKQ8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LKQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKQ8/entry#A0A8C2LKQ8-1", "sequence": { "sequence": "MNGPALLRRNASKRGLEKLLRLTTQWREEDKEEAAREQRQRERERQLQDQDQDKVEDEGDHSLEQPEQQALLSLKSSELDEDEGFGDWSQKMEQRQQCWENEGTAEGTEPSQNESPEETQAEDRSQQVKVHLEELNLSQEEPSPEDTVGSCEEAEENLASHQARTPSPLALEETVEPSSPPLSPTTTLADRTESLNRSIKKSNSVKKSQPTLPISTIDERLQQYTQATESAGRTPKLSRQPSIELPSMAVASTKTRWETGEVQTQSASKTPSCQDIVAGDMSKKSLWEQKGSSKISSTIKSTPSGKRYKFVATGHGKYEKVLVDEGSAP", "length": 329, "header": "tr|A0A8C2LKQ8-1|A0A8C2LKQ8_CRIGR Isoform 1 of Lymphocyte-specific protein 1 OS=Cricetulus griseus OX=10029 GN=Lsp1 PE=4 SV=1 CANONICAL=A0A8C2LKQ8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LKQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKQ8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LKQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKQ8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767209", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767209", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AFG3-1", "protein_name": "Lymphocyte specific protein 1", "gene_name": "LSP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAEAPSHPDSEEQQELLVEEGSGLAAQWSLEDEEEAARERRRRERDRQLQGQDEDEGGPGPEQQEQEKLLKPPDAPELDEDEGFGDWSQKPEQRRQPWGPGETSDSGDPLQGESPEGEQEEDSWPPDSRGHCSSSVDPPAPDRPPCPPHLPGHASPPPRLNGPSVCLLLARTPAHLGWPGQHVCGSPARVCLEELCLSPDSELQEELGSEASEPRGPAGPVQGSPGLAETEEGDVQPQRCQQPRTPSPSVLEGTAPGSPPLSPSTKLIDRTESLHRSIQKSNSVKKSQPALPISKIDGRLEQYTQAIETAGRAHKLTRQPSIELPSMAVASTKSRWETGEVQAQSAAKPPSCKDIVAGDMSKKSLWEQKGGPKTSSTVKSTPSGKRYKFVAAGHGKYEKVLVDEGSVP", "length": 408 }, "evidence": [ { "id": "A0A8C2LKQ8", "url": "https://omabrowser.org/oma/group/A0A8C2LKQ8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5ZYW3-1", "protein_name": "Lymphocyte-specific protein 1", "gene_name": "Lsp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "WRPRSRGWGSPTLAGRVAGGRHPHGPGGLSARACPAWSLAELAAGGTGTKWPSPLGRVSGPEPRGLRFRFQSQPVRQSWVDQTASSNQGAKAPRDSPTLCFCRSQEGTPRDSWDPWDSCRGTVPRDTATGPEHLAREQCQDGAPRSVEDRLTTQWREEDEEEAAREQRQRERERQLQDQDKDEEDEGGHFLEQPGQQALVSLKSSELDEDEGFGDWSQKQEPPRQQSWENEGTAEGSEPSPSESAEEKQTEDSSHQAKVHLEESNLSHSDPNIEDDVGGSGETEEHLISHQARTPSPLALEDTAELSSPPLSPTVKLADRTESLNRSIQKSNSVKKSQPTLPISTIDERLQQYTQATESAGRTPKLSRQPSIELPSMAVASTKTLWETGEVQTQSASKTPSCQDIVAGDMSKKSLWEQKGGSKISSTIKSTPSGKRYKFVATGHGKYEKVLVDEGSAP", "length": 458 }, "evidence": [ { "id": "A0A8C2LKQ8", "url": "https://omabrowser.org/oma/group/A0A8C2LKQ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P19973-1", "protein_name": "Lymphocyte-specific protein 1", "gene_name": "Lsp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEAAIDPRCEEQEELHAEDSEGLTTQWREEDEEEAAREQRQRERERQLQDQDKDKEDDGGHSLEQPGQQTLISLKSSELDEDEGFGDWSQKPEPRQQFWGNEGTAEGTEPSQSERPEEKQTEESSHQAKVHLEESNLSYREPDPEDAVGGSGEAEEHLIRHQVRTPSPLALEDTVELSSPPLSPTTKLADRTESLNRSIKKSNSVKKSQPTLPISTIDERLQQYTQATESSGRTPKLSRQPSIELPSMAVASTKTLWETGEVQSQSASKTPSCQDIVAGDMSKKSLWEQKGGSKISSTIKSTPSGKRYKFVATGHGKYEKVLVDEGSAP", "length": 330 }, "evidence": [ { "id": "A0A8C2LKQ8", "url": "https://omabrowser.org/oma/group/A0A8C2LKQ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P33241-1", "protein_name": "Lymphocyte-specific protein 1", "gene_name": "LSP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEASSDPGAEEREELLGPTAQWSVEDEEEAVHEQCQHERDRQLQAQDEEGGGHVPERPKQEMLLSLKPSEAPELDEDEGFGDWSQRPEQRQQHEGAQGALDSGEPPQCRSPEGEQEDRPGLHAYEKEDSDEVHLEELSLSKEGPGPEDTVQDNLGAAGAEEEQEEHQKCQQPRTPSPLVLEGTIEQSSPPLSPTTKLIDRTESLNRSIEKSNSVKKSQPDLPISKIDQWLEQYTQAIETAGRTPKLARQASIELPSMAVASTKSRWETGEVQAQSAAKTPSCKDIVAGDMSKKSLWEQKGGSKTSSTIKSTPSGKRYKFVATGHGKYEKVLVEGGPAP", "length": 339 }, "evidence": [ { "id": "A0A8C2LKQ8", "url": "https://omabrowser.org/oma/group/A0A8C2LKQ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LKQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKQ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LKQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKQ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 10, "end_pos": 12, "annotation": "n_glycosylation_sequon" }, { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 10, "end_pos": 12 }, { "start_pos": 113, "end_pos": 115 }, { "start_pos": 136, "end_pos": 138 }, { "start_pos": 196, "end_pos": 198 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LKW5-1", "uniprot_ac": "A0A8C2LKW5", "uniprot_id": "A0A8C2LKW5_CRIGR", "mass": { "chemical_mass": 341580.0, "monoisotopic_mass": 341580.0 }, "refseq": { "ac": "XP_027270870", "name": "dmX-like protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270870" }, "gene_names": [ { "name": "Dmxl2", "type": "recommended", "evidence": [ { "id": "A0A8C2LKW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKW5" } ] }, { "name": "Dmxl2", "type": "synonym", "evidence": [ { "id": "XP_027270870", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270870" } ] } ], "protein_names": [ { "name": "DmX-like protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8C2LKW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKW5/entry#names_and_taxonomy" } ] }, { "name": "dmX-like protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027270870", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270870" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027270870", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270870" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LKW5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKW5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dmxl2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKW5", "locus": {} } ], "crossref": [ { "id": "100753187", "url": "https://www.ncbi.nlm.nih.gov/gene/100753187", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] 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"database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13950:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13950:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12234", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12234", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027270870", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027270870", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LKW5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LKW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKW5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LLY7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LLY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLY7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GYA5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GYA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYA5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GYL5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GYL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYL5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JXZ0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JXZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JXZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K5C9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5C9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K5C9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5C9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHLHQVLTGAVNPGDNCYSVGSVGDVPFTAYGSGCDIVILASDFECVQIIPGAKHGNIQVSCVECSNQHGRVAASYGNAVCIFEPLGINSHKRNSQLKCQWLKTGQFFLSSVTYNLAWDPQDNRLLTATDAIQLWAPPGSDILEEEEEVDNKIPPVLNDWKCIWQCKTSVSVHLMEWSPDGEYFATAGKDDCLLKVWYPMTGWKSSIIPQDHHEVKRRQASTQFSFVYLAHPRAVTGFSWRKTSKYMPRGSVCNVLLTSCHDGVCRLWAETLLPEDCLLGEQICETTTSSITSNLSHAGKHKDRIQHALETIHHLKNLRKGQRRSSVLVTHTELMPDKTATHEVQRHISHHANALCHFHIAASINPATDIPNVLVGTAFNIDDVNGGFVVHWLNNKEFHFTSSAEIFMHQLRKLSEKQLEHESDDANREDEEGSQEERERGLHMRLDHELSLDRESEAGTGSSEHEDGEREGSPRTHPGHSIAVPLPTVLLDRKIETLLTEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIFRQVQVSFSSRIPVAFPSGDANSLSKNIMMYACVNATKDSYHTSSHQELMSVDSSHGSQPHSRLHSTDMNILAPTVMMVSKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCGHRFHLNDLACHSVLPLLLTSSHHNALLTPESDCQWDSDSKVNRLIDPVKHTKESLKQPLRNAATRTFHDPNAIYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASACFVASDGKNLRLYQAVVDARKLLDELSDPEASKLIGEVFNIVSQQSTARPGCIIELDAITDQCGSNTQLLHVFQEDFIIGYKPHKDDTEKKKKETEIFFQPSQGYRPPPFSEKFFLVVIEKDSNNNSVLHMWHLHLKSVQACLAKVTEGISTDNLLSVPGQKKVDSSPETSPSVSSMPHSLSIANLQTASKLILSSRLVYSQPLDLPEAVEVIRATPSAGHLSSSSIYPVCLAPYLVVTTCSDNKVRFWKCCMETNTLCSISDEKETYHWRRWPLMNDEGEDNSSTVSIVGRPVAVSCSYTGRLAVAYKQPVHHNGFISKEFSMHVCIFECESTGGSEWVLEQTIHLDDLVKVGSVLDSRVSVDSNLFVYSKSDAFLSKDRYLIPNIKHLVHLDWVSKEDGSHILTVGVGANIFMYGRLSGIVTDQTNSKDGGVAVITLPLGGSIKQGVRSRWVLLRSIDLVSSVDGTPSLPVSLSWVRDGILVVGMDCEMHVYAQWKHSVKFGDIEADSPVEETVIQDHSTFKSTMLPRKSIVEGATITDDVFGSPTVVQDGGLFEAAHALSPTLPQYHPTQLLELMDLGKVRRAKAILSHLVKCIAGEVAIVRDPDAGEGTKRHLSRTISVSGSTAKDTVTIGKDGARDYTEIDSIPPLPLHALLAADQDTSYRISEESTKKPQSYEAHIESQPGDQYSELFQVQEITTDDIDLEPEKRENKSKVINLSQYGPAYFGQEHARVLSSHLMHSSLPGLTRLEQMFLVALADTVATTSTELDENRDKYSGRDTLDECGLRYLLAMRLHTCLLTSLPPLYRAQLLHQGVSTCHFAWAFHSEAEEELINMIPAIQRGDPQWSELRAMGIGWWVRNVNTLRRCIEKVAKASFQRNNDALDAALFYLSMKKKAVVWGLFRSQHDEKMTTFFSHNFNEDRWRKAALKNAFSLLGKQRFEQSAAFFLLAGSLKDAIEVCLEKMEDIQLAMVIARLFESEFETSSTYISILNQKILGREKDGSEFNCKRLHADPFLRSLAYWVMKDYTRALDTLLEQTPKEDDEQQVIIKSCNPVVFSFYNYLRTHPLLIRRNLASPEGTLATLGLKTEKNIADKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVTKMSSLTAKKDPLDFTSERMENGPSKSGALNDGSGSSGAAWSAKASSQFDWSQPIVTVDEEPLQLDWGEDHDSALEEDDTGGLVMKSTDVKKDGQDHKASDHSALLTPQEEDCVLGDSEVDVIAEQLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEICNHESVIKEYSSKTYSKVESELLDHEEMVDKPDIGSYERHQIERRRLQAKREHAERRKLWLQKNQDLLRVFLSYCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIANPVLYLNNHIHDILYTIVQMKTPPHPNVEDMKVHTLHSLAASLSASIYQALCDSHSYSQTEGNQFTGMAYQGLLLSDRRRLRTESIEEHATPNSAPAQWPGVSSLINLLSSAQDEDQPKLNVLLCEAVVAVYLSLLIHALATNSSNELFRLAAHPLNNRMWAAVFGGGVKLVVKPRRQSESIAAPPVPSEDIDKHRRRFNMRMLVPGRPVKDATPPPVPAERPSYKEKFISPELSMWDYFIAKPFLPLSDSGVIYDSDESVHSDDEEDDAFFSDTQIQEHQDPNSYSWALLHLTMVKLALHNIKNFFPIAGLEFSELPVTSPLGIAVIKNLENWEQILQEKMDRFEGPPPNYVNTYPTDLSVGAGPAILRNKAMLEPENTPFKSRDASALPVKRLWHFLVKQEVLQETFIRYIFTKKRKQSESVEEHVEHVKHNYVAEECPIKVEADLGYPGGKAKVIHKESDMIMAFSINKANSNEIVLASTHDVQELDVTSLLACQSYIWIGEEYDRESKSSDDIDYRGSTTTLYQPGAASHSTSQVHPPPSLPWLGSGQTSTGATVLMKRNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGQSNDNRNVCFWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGYICIFDIRQRQLLHTFQAHDSAIKALALDPCEEYFTTGSAEGNIKVWRLTGHGLIHSFKNEHAKQSIFRNIGAGVMQIDISQDNRLFSCGADGTLKTRVLPSAFNIPNRILDIL", "length": 3055, "header": "tr|A0A8C2LKW5-1|A0A8C2LKW5_CRIGR Isoform 1 of DmX-like protein 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Dmxl2 PE=4 SV=1 CANONICAL=A0A8C2LKW5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LKW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKW5/entry#A0A8C2LKW5-1", "sequence": { "sequence": "MHLHQVLTGAVNPGDNCYSVGSVGDVPFTAYGSGCDIVILASDFECVQIIPGAKHGNIQVSCVECSNQHGRVAASYGNAVCIFEPLGINSHKRNSQLKCQWLKTGQFFLSSVTYNLAWDPQDNRLLTATDAIQLWAPPGSDILEEEEEVDNKIPPVLNDWKCIWQCKTSVSVHLMEWSPDGEYFATAGKDDCLLKVWYPMTGWKSSIIPQDHHEVKRRQASTQFSFVYLAHPRAVTGFSWRKTSKYMPRGSVCNVLLTSCHDGVCRLWAETLLPEDCLLGEQICETTTSSITSNLSHAGKHKDRIQHALETIHHLKNLRKGQRRSSVLVTHTELMPDKTATHEVQRHISHHANALCHFHIAASINPATDIPNVLVGTAFNIDDVNGGFVVHWLNNKEFHFTSSAEIFMHQLRKLSEKQLEHESDDANREDEEGSQEERERGLHMRLDHELSLDRESEAGTGSSEHEDGEREGSPRTHPGHSIAVPLPTVLLDRKIETLLTEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIFRQVQVSFSSRIPVAFPSGDANSLSKNIMMYACVNATKDSYHTSSHQELMSVDSSHGSQPHSRLHSTDMNILAPTVMMVSKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCGHRFHLNDLACHSVLPLLLTSSHHNALLTPESDCQWDSDSKVNRLIDPVKHTKESLKQPLRNAATRTFHDPNAIYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASACFVASDGKNLRLYQAVVDARKLLDELSDPEASKLIGEVFNIVSQQSTARPGCIIELDAITDQCGSNTQLLHVFQEDFIIGYKPHKDDTEKKKKETEIFFQPSQGYRPPPFSEKFFLVVIEKDSNNNSVLHMWHLHLKSVQACLAKVTEGISTDNLLSVPGQKKVDSSPETSPSVSSMPHSLSIANLQTASKLILSSRLVYSQPLDLPEAVEVIRATPSAGHLSSSSIYPVCLAPYLVVTTCSDNKVRFWKCCMETNTLCSISDEKETYHWRRWPLMNDEGEDNSSTVSIVGRPVAVSCSYTGRLAVAYKQPVHHNGFISKEFSMHVCIFECESTGGSEWVLEQTIHLDDLVKVGSVLDSRVSVDSNLFVYSKSDAFLSKDRYLIPNIKHLVHLDWVSKEDGSHILTVGVGANIFMYGRLSGIVTDQTNSKDGGVAVITLPLGGSIKQGVRSRWVLLRSIDLVSSVDGTPSLPVSLSWVRDGILVVGMDCEMHVYAQWKHSVKFGDIEADSPVEETVIQDHSTFKSTMLPRKSIVEGATITDDVFGSPTVVQDGGLFEAAHALSPTLPQYHPTQLLELMDLGKVRRAKAILSHLVKCIAGEVAIVRDPDAGEGTKRHLSRTISVSGSTAKDTVTIGKDGARDYTEIDSIPPLPLHALLAADQDTSYRISEESTKKPQSYEAHIESQPGDQYSELFQVQEITTDDIDLEPEKRENKSKVINLSQYGPAYFGQEHARVLSSHLMHSSLPGLTRLEQMFLVALADTVATTSTELDENRDKYSGRDTLDECGLRYLLAMRLHTCLLTSLPPLYRAQLLHQGVSTCHFAWAFHSEAEEELINMIPAIQRGDPQWSELRAMGIGWWVRNVNTLRRCIEKVAKASFQRNNDALDAALFYLSMKKKAVVWGLFRSQHDEKMTTFFSHNFNEDRWRKAALKNAFSLLGKQRFEQSAAFFLLAGSLKDAIEVCLEKMEDIQLAMVIARLFESEFETSSTYISILNQKILGREKDGSEFNCKRLHADPFLRSLAYWVMKDYTRALDTLLEQTPKEDDEQQVIIKSCNPVVFSFYNYLRTHPLLIRRNLASPEGTLATLGLKTEKNIADKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVTKMSSLTAKKDPLDFTSERMENGPSKSGALNDGSGSSGAAWSAKASSQFDWSQPIVTVDEEPLQLDWGEDHDSALEEDDTGGLVMKSTDVKKDGQDHKASDHSALLTPQEEDCVLGDSEVDVIAEQLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEICNHESVIKEYSSKTYSKVESELLDHEEMVDKPDIGSYERHQIERRRLQAKREHAERRKLWLQKNQDLLRVFLSYCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIANPVLYLNNHIHDILYTIVQMKTPPHPNVEDMKVHTLHSLAASLSASIYQALCDSHSYSQTEGNQFTGMAYQGLLLSDRRRLRTESIEEHATPNSAPAQWPGVSSLINLLSSAQDEDQPKLNVLLCEAVVAVYLSLLIHALATNSSNELFRLAAHPLNNRMWAAVFGGGVKLVVKPRRQSESIAAPPVPSEDIDKHRRRFNMRMLVPGRPVKDATPPPVPAERPSYKEKFISPELSMWDYFIAKPFLPLSDSGVIYDSDESVHSDDEEDDAFFSDTQIQEHQDPNSYSWALLHLTMVKLALHNIKNFFPIAGLEFSELPVTSPLGIAVIKNLENWEQILQEKMDRFEGPPPNYVNTYPTDLSVGAGPAILRNKAMLEPENTPFKSRDASALPVKRLWHFLVKQEVLQETFIRYIFTKKRKQSESVEEHVEHVKHNYVAEECPIKVEADLGYPGGKAKVIHKESDMIMAFSINKANSNEIVLASTHDVQELDVTSLLACQSYIWIGEEYDRESKSSDDIDYRGSTTTLYQPGAASHSTSQVHPPPSLPWLGSGQTSTGATVLMKRNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGQSNDNRNVCFWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGYICIFDIRQRQLLHTFQAHDSAIKALALDPCEEYFTTGSAEGNIKVWRLTGHGLIHSFKNEHAKQSIFRNIGAGVMQIDISQDNRLFSCGADGTLKTRVLPSAFNIPNRILDIL", "length": 3055, "header": "tr|A0A8C2LKW5-1|A0A8C2LKW5_CRIGR Isoform 1 of DmX-like protein 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Dmxl2 PE=4 SV=1 CANONICAL=A0A8C2LKW5-1" }, "locus": {} }, { "isoform_ac": "A0A8C2LLY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKW5/entry#A0A8C2LLY7-1", "sequence": { "sequence": "MHLHQVLTGAVNPGDNCYSVGSVGDVPFTAYGSGCDIVILASDFECVQIIPGAKHGNIQVSCVECSNQHGRVAASYGNAVCIFEPLGINSHKRNSQLKCQWLKTGQFFLSSVTYNLAWDPQDNRLLTATDAIQLWAPPGSDILEEEEEVDNKIPPVLNDWKCIWQCKTSVSVHLMEWSPDGEYFATAGKDDCLLKVWYPMTGWKSSIIPQDHHEVKRRQASTQFSFVYLAHPRAVTGFSWRKTSKYMPRGSVCNVLLTSCHDGVCRLWAETLLPEDCLLGEQICETTTSSITSNLSHAGKHKDRIQHALETIHHLKNLRKGQRRSSVLVTHTELMPDKTATHEVQRHISHHANALCHFHIAASINPATDIPNVLVGTAFNIDDVNGGFVVHWLNNKEFHFTSSAEIFMHQLRKLSEKQLEHESDDANREDEEGSQEERERGLHMRLDHELSLDRESEAGTGSSEHEDGEREGSPRTHPGHSIAVPLPTVLLDRKIETLLTEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIFRQVQVSFSSRIPVAFPSGDANSLSKNIMMYACVNATKDSYHTSSHQELMSVDSSHGSQPHSRLHSTDMNILAPTVMMVSKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCGHRFHLNDLACHSVLPLLLTSSHHNALLTPESDCQWDSDSKVNRLIDPVKHTKESLKQPLRNAATRTFHDPNAIYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASACFVASDGKNLRLYQAVVDARKLLDELSDPEASKLIGEVFNIVSQQSTARPGCIIELDAITDQCGSNTQLLHVFQEDFIIGYKPHKDDTEKKKKETEIFFQPSQGYRPPPFSEKFFLVVIEKDSNNNSVLHMWHLHLKSVQACLAKVTEGISTDNLLSVPGQKKVDSSPETSPSVSSMPHSLSIANLQTASKLILSSRLVYSQPLDLPEAVEVIRATPSAGHLSSSSIYPVCLAPYLVVTTCSDNKVRFWKCCMETNTLCSISDEKETYHWRRWPLMNDEGEDNSSTVSIVGRPVAVSCSYTGRLAVAYKQPVHHNGFISKEFSMHVCIFECESTGGSEWVLEQTIHLDDLVKVGSVLDSRVSVDSNLFVYSKSDAFLSKDRYLIPNIKHLVHLDWVSKEDGSHILTVGVGANIFMYGRLSGIVTDQTNSKDGGVAVITLPLGGSIKQGVRSRWVLLRSIDLVSSVDGTPSLPVSLSWVRDGILVVGMDCEMHVYAQWKHSVKFGDIEADSPVEETVIQDHSTFKSTMLPRKSIVEGATITDDVFGSPTVVQDGGLFEAAHALSPTLPQYHPTQLLELMDLGKVRRAKAILSHLVKCIAGEVAIVRDPDAGEGTKRHLSRTISVSGSTAKDTVTIGKDGARDYTEIDSIPPLPLHALLAADQDTSYRISEESTKKPQSYEAHIESQPGDQYSELFQVQEITTDDIDLEPEKRENKSKVINLSQYGPAYFGQEHARVLSSHLMHSSLPGLTRLEQMFLVALADTVATTSTELDENRDKYSGRDTLDECGLRYLLAMRLHTCLLTSLPPLYRAQLLHQGVSTCHFAWAFHSEAEEELINMIPAIQRGDPQWSELRAMGIGWWVRNVNTLRRCIEKVAKASFQRNNDALDAALFYLSMKKKAVVWGLFRSQHDEKMTTFFSHNFNEDRWRKAALKNAFSLLGKQRFEQSAAFFLLAGSLKDAIEVCLEKMEDIQLAMVIARLFESEFETSSTYISILNQKILGREKDGSEFNCKRLHADPFLRSLAYWVMKDYTRALDTLLEQTPKEDDEQQVIIKSCNPVVFSFYNYLRTHPLLIRRNLASPEGTLATLGLKTEKNIADKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVTKMSSLTAKKDPLDFTSERMENGPSKSGALNDGSGSSGAAWSAKASSQFDWSQPIVTVDEEPLQLDWGEDHDSALEEDDTGGLVMKSTDVKKDGQDHKASDHSALLTPQEEDCVLGDSEVDVIAEQLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEICNHESVIKEYSSKTYSKVESELLDHEEMVDKPDIGSYERHQIERRRLQAKREHAERRKLWLQKNQDLLRVFLSYCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIANPVLYLNNHIHDILYTIVQMKTPPHPNVEDMKVHTLHSLAASLSASIYQALCDSHSYSQTEGNQFTGMAYQGLLLSDRRRLRTESIEEHATPNSAPAQWPGVSSLINLLSSAQDEDQPKLNVLLCEAVVAVYLSLLIHALATNSSNELFRLAAHPLNNRMWAAVFGGGVKLVVKPRRQSESIAAPPVPSEDIDKHRRRFNMRMLVPGRPVKDATPPPVPAERPSYKEKFISPELSMWDYFIAKPFLPLSDSGVIYDSDESVHSDDEEDDAFFSDTQIQEHQDPNSYSWALLHLTMVKLALHNIKNFFPIAGLEFSELPVTSPLGIAVIKNLENWEQILQEKMDRFEGPPPNYVNTYPTDLSVGAGPAILRNKAMLEPENTPFKSRDASALPVKRLWHFLVKQEVLQETFIRYIFTKKRKQSEVEADLGYPGGKAKVIHKESDMIMAFSINKANSNEIVLASTHDVQELDVTSLLACQSYIWIGEEYDRESKSSDDIDYRGSTTTLYQPGAASHSTSQVHPPPSLPWLGSGQTSTGATVLMKRNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGQSNDNRNVCFWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGYICIFDIRQRQLLHTFQAHDSAIKALALDPCEEYFTTGSAEGNIKVWRLTGHGLIHSFKNEHAKQSIFRNIGAGVMQIDISQDNRLFSCGADGTLKTRVLPSAFNIPNRILDIL", "length": 3034, "header": "tr|A0A8C2LLY7-1|A0A8C2LLY7_CRIGR Computationally mapped isoform of DmX-like protein 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Dmxl2 PE=4 SV=1 CANONICAL=A0A8C2LKW5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GYA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKW5/entry#A0A9J7GYA5-1", "sequence": { "sequence": "MHLHQVLTGAVNPGDNCYSVGSVGDVPFTAYGSGCDIVILASDFECVQIIPGAKHGNIQVSCVECSNQHGRVAASYGNAVCIFEPLGINSHKRNSQLKCQWLKTGQFFLSSVTYNLAWDPQDNRLLTATDAIQLWAPPGSDILEEEEEVDNKIPPVLNDWKCIWQCKTSVSVHLMEWSPDGEYFATAGKDDCLLKVWYPMTGWKSSIIPQDHHEVKRRQASTQFSFVYLAHPRAVTGFSWRKTSKYMPRGSVCNVLLTSCHDGVCRLWAETLLPEDCLLGEQICETTTSSITSNLSHAGKHKDRIQHALETIHHLKNLRKGQRRSSVLVTHTELMPDKTATHEVQRHISHHANALCHFHIAASINPATDIPNVLVGTAFNIDDVNGGFVVHWLNNKEFHFTSSAEIFMHQLRKLSEKQLEHESDDANREDEEGSQEERERGLHMRLDHELSLDRESEAGTGSSEHEDGEREGSPRTHPGHSIAVPLPTVLLDRKIETLLTEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIFRQVQVSFSSRIPVAFPSGDANSLSKNIMMYACVNATKDSYHTSSHQELMSVDSSHGSQPHSRLHSTDMNILAPTVMMVSKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCGHRFHLNDLACHSVLPLLLTSSHHNALLTPESDCQWDSDSKVNRLIDPVKHTKESLKQPLRNAATRTFHDPNAIYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASACFVASDGKNLRLYQAVVDARKLLDELSDPEASKLIGEVFNIVSQQSTARPGCIIELDAITDQCGSNTQLLHVFQEDFIIGYKPHKDDTEKKKKETEIFFQPSQGYRPPPFSEKFFLVVIEKDSNNNSVLHMWHLHLKSVQACLAKVTEGISTDNLLSVPGQKKVDSSPETSPSVSSMPHSLSIANLQTASKLILSSRLVYSQPLDLPEAVEVIRATPSAGHLSSSSIYPVCLAPYLVVTTCSDNKVRFWKCCMETNTLCSISDEKETYHWRRWPLMNDEGEDNSSTVSIVGRPVAVSCSYTGRLAVAYKQPVHHNGFISKEFSMHVCIFECESTGGSEWVLEQTIHLDDLVKVGSVLDSRVSVDSNLFVYSKSDAFLSKDRYLIPNIKHLVHLDWVSKEDGSHILTVGVGANIFMYGRLSGIVTDQTNSKDGGVAVITLPLGGSIKQGVRSRWVLLRSIDLVSSVDGTPSLPVSLSWVRDGILVVGMDCEMHVYAQWKHSVKFGDIEADSPVEETVIQDHSTFKSTMLPRKSIVEGATITDDVFGSPTVVQDGGLFEAAHALSPTLPQYHPTQLLELMDLGKVRRAKAILSHLVKCIAGEVAIVRDPDAGEGTKRHLSRTISVSGSTAKDTVTIGKDGARDYTEIDSIPPLPLHALLAADQDTSYRISEESTKKPQSYEAHIESQPGDQYSELFQVQEITTDDIDLEPEKRENKSKVINLSQYGPAYFGQEHARVLSSHLMHSSLPGLTRLEQMFLVALADTVATTSTELDENRDKYSGRDTLDECGLRYLLAMRLHTCLLTSLPPLYRAQLLHQGVSTCHFAWAFHSEAEEELINMIPAIQRGDPQWSELRAMGIGWWVRNVNTLRRCIEKVAKASFQRNNDALDAALFYLSMKKKAVVWGLFRSQHDEKMTTFFSHNFNEDRWRKAALKNAFSLLGKQRFEQSAAFFLLAGSLKDAIEVCLEKMEDIQLAMVIARLFESEFETSSTYISILNQKILGREKDGSEFNCKRLHADPFLRSLAYWVMKDYTRALDTLLEQTPKEDDEQQVIIKSCNPVVFSFYNYLRTHPLLIRRNLASPEGTLATLGLKTEKNIADKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVTKMSSLTAKKDPLDFTSERMENGPSKSGALNDGSGSSGAAWSAKASSQFDWSQPIVTVDEEPLQLDWGEDHDSALEEDDTGGLVMKSTDVKKDGQDHKASDHSALLTPQEEDCVLGDSEVDVIAEQLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEICNHESVIKEYSSKTYSKVESELLDHEEMVDKPDIGSYERHQIERRRLQAKREHAERRKLWLQKNQDLLRVFLSYCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIANPVLYLNNHIHDILYTIVQMKTPPHPNVEDMKVHTLHSLAASLSASIYQALCDSHSYSQTEGNQFTGMAYQGLLLSDRRRLRTESIEEHATPNSAPAQWPGVSSLINLLSSAQDEDQPKLNVLLCEAVVAVYLSLLIHALATNSSNELFRLAAHPLNNRMWAAVFGGGVKLVVKPRRQSESIAAPPVPSEDIDKHRRRFNMRMLVPGRPVKDATPPPVPAERPSYKEKFISPELSMWDYFIAKPFLPLSDSGVIYDSDESVHSDDEEDDAFFSDTQIQEHQDPNSYRSRDASALPVKRLWHFLVKQEVLQETFIRYIFTKKRKQSESVEEHVEHVKHNYVAEECPIKVEADLGYPGGKAKVIHKESDMIMAFSINKANSNEIVLASTHDVQELDVTSLLACQSYIWIGEEYDRESKSSDDIDYRGSTTTLYQPGAASHSTSQVHPPPSLPWLGSGQTSTGATVLMKRNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGQSNDNRNVCFWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGYICIFDIRQRQLLHTFQAHDSAIKALALDPCEEYFTTGSAEGNIKVWRLTGHGLIHSFKNEHAKQSIFRNIGAGVMQIDISQDNRLFSCGADGTLKTRVLPSAFNIPNRILDIL", "length": 2959, "header": "tr|A0A9J7GYA5-1|A0A9J7GYA5_CRIGR Computationally mapped isoform of DmX-like protein 2 isoform X3 OS=Cricetulus griseus OX=10029 GN=Dmxl2 PE=4 SV=1 CANONICAL=A0A8C2LKW5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GYL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKW5/entry#A0A9J7GYL5-1", "sequence": { "sequence": "MHLHQVLTGAVNPGDNCYSVGSVGDVPFTAYGSGCDIVILASDFECVQIIPGAKHGNIQVSCVECSNQHGRVAASYGNAVCIFEPLGINSHKRNSQLKCQWLKTGQFFLSSVTYNLAWDPQDNRLLTATDAIQLWAPPGSDILEEEEEVDNKIPPVLNDWKCIWQCKTSVSVHLMEWSPDGEYFATAGKDDCLLKVWYPMTGWKSSIIPQDHHEVKRRQASTQFSFVYLAHPRAVTGFSWRKTSKYMPRGSVCNVLLTSCHDGVCRLWAETLLPEDCLLGEQICETTTSSITSNLSHAGKHKDRIQHALETIHHLKNLRKGQRRSSVLVTHTELMPDKTATHEVQRHISHHANALCHFHIAASINPATDIPNVLVGTAFNIDDVNGGFVVHWLNNKEFHFTSSAEIFMHQLRKLSEKQLEHESDDANREDEEGSQEERERGLHMRLDHELSLDRESEAGTGSSEHEDGEREGSPRTHPGHSIAVPLPTVLLDRKIETLLTEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIFRQVQVSFSSRIPVAFPSGDANSLSKNIMMYACVNATKDSYHTSSHQELMSVDSSHGSQPHSRLHSTDMNILAPTVMMVSKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCGHRFHLNDLACHSVLPLLLTSSHHNALLTPESDCQWDSDSKVNRLIDPVKHTKESLKQPLRNAATRTFHDPNAIYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASACFVASDGKNLRLYQAVVDARKLLDELSDPEASKLIGEVFNIVSQQSTARPGCIIELDAITDQCGSNTQLLHVFQEDFIIGYKPHKDDTEKKKKETEIFFQPSQGYRPPPFSEKFFLVVIEKDSNNNSVLHMWHLHLKSVQACLGRDTLDECGLRYLLAMRLHTCLLTSLPPLYRAQLLHQGVSTCHFAWAFHSEAEEELINMIPAIQRGDPQWSELRAMGIGWWVRNVNTLRRCIEKVAKASFQRNNDALDAALFYLSMKKKAVVWGLFRSQHDEKMTTFFSHNFNEDRWRKAALKNAFSLLGKQRFEQSAAFFLLAGSLKDAIEVCLEKMEDIQLAMVIARLFESEFETSSTYISILNQKILGREKDGSEFNCKRLHADPFLRSLAYWVMKDYTRALDTLLEQTPKEDDEQQVIIKSCNPVVFSFYNYLRTHPLLIRRNLASPEGTLATLGLKTEKNIADKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVTKMSSLTAKKDPLDFTSERMENGPSKSGALNDGSGSSGAAWSAKASSQFDWSQPIVTVDEEPLQLDWGEDHDSALEEDDTGGLVMKSTDVKKDGQDHKASDHSALLTPQEEDCVLGDSEVDVIAEQLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEICNHESVIKEYSSKTYSKVESELLDHEEMVDKPDIGSYERHQIERRRLQAKREHAERRKLWLQKNQDLLRVFLSYCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIANPVLYLNNHIHDILYTIVQMKTPPHPNVEDMKVHTLHSLAASLSASIYQALCDSHSYSQTEGNQFTGMAYQGLLLSDRRRLRTESIEEHATPNSAPAQWPGVSSLINLLSSAQDEDQPKLNVLLCEAVVAVYLSLLIHALATNSSNELFRLAAHPLNNRMWAAVFGGGVKLVVKPRRQSESIAAPPVPSEDIDKHRRRFNMRMLVPGRPVKDATPPPVPAERPSYKEKFISPELSMWDYFIAKPFLPLSDSGVIYDSDESVHSDDEEDDAFFSDTQIQEHQDPNSYSWALLHLTMVKLALHNIKNFFPIAGLEFSELPVTSPLGIAVIKNLENWEQILQEKMDRFEGPPPNYVNTYPTDLSVGAGPAILRNKAMLEPENTPFKSRDASALPVKRLWHFLVKQEVLQETFIRYIFTKKRKQSEVEADLGYPGGKAKVIHKESDMIMAFSINKANSNEIVLASTHDVQELDVTSLLACQSYIWIGEEYDRESKSSDDIDYRGSTTTLYQPGAASHSTSQVHPPPSLPWLGSGQTSTGATVLMKRNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGQSNDNRNVCFWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGYICIFDIRQRQLLHTFQAHDSAIKALALDPCEEYFTTGSAEGNIKVWRLTGHGLIHSFKNEHAKQSIFRNIGAGVMQIDISQDNRLFSCGADGTLKTRVLPSAFNIPNRILDIL", "length": 2399, "header": "tr|A0A9J7GYL5-1|A0A9J7GYL5_CRIGR Computationally mapped isoform of DmX-like protein 2 isoform X5 OS=Cricetulus griseus OX=10029 GN=Dmxl2 PE=4 SV=1 CANONICAL=A0A8C2LKW5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JXZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKW5/entry#A0A9J7JXZ0-1", "sequence": { "sequence": "MHLHQVLTGAVNPGDNCYSVGSVGDVPFTAYGSGCDIVILASDFECVQIIPGAKHGNIQVSCVECSNQHGRVAASYGNAVCIFEPLGINSHKRNSQLKCQWLKTGQFFLSSVTYNLAWDPQDNRLLTATDAIQLWAPPGSDILEEEEEVDNKIPPVLNDWKCIWQCKTSVSVHLMEWSPDGEYFATAGKDDCLLKVWYPMTGWKSSIIPQDHHEVKRRQASTQFSFVYLAHPRAVTGFSWRKTSKYMPRGSVCNVLLTSCHDGVCRLWAETLLPEDCLLGEQICETTTSSITSNLSHAGKHKDRIQHALETIHHLKNLRKGQRRSSVLVTHTELMPDKTATHEVQRHISHHANALCHFHIAASINPATDIPNVLVGTAFNIDDVNGGFVVHWLNNKEFHFTSSAEIFMHQLRKLSEKQLEHESDDANREDEEGSQEERERGLHMRLDHELSLDRESEAGTGSSEHEDGEREGSPRTHPGHSIAVPLPTVLLDRKIETLLTEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIFRQVQVSFSSRIPVAFPSGDANSLSKNIMMYACVNATKDSYHTSSHQELMSVDSSHGSQPHSRLHSTDMNILAPTVMMVSKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCGHRFHLNDLACHSVLPLLLTSSHHNALLTPESDCQWDSDSKVNRLIDPVKHTKESLKQPLRNAATRTFHDPNAIYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASACFVASDGKNLRLYQAVVDARKLLDELSDPEASKLIGEVFNIVSQQSTARPGCIIELDAITDQCGSNTQLLHVFQEDFIIGYKPHKDDTEKKKKETEIFFQPSQGYRPPPFSEKFFLVVIEKDSNNNSVLHMWHLHLKSVQACLGVSTCHFAWAFHSEAEEELINMIPAIQRGDPQWSELRAMGIGWWVRNVNTLRRCIEKVAKASFQRNNDALDAALFYLSMKKKAVVWGLFRSQHDEKMTTFFSHNFNEDRWRKAALKNAFSLLGKQRFEQSAAFFLLAGSLKDAIEVCLEKMEDIQLAMVIARLFESEFETSSTYISILNQKILGREKDGSEFNCKRLHADPFLRSLAYWVMKDYTRALDTLLEQTPKEDDEQQVIIKSCNPVVFSFYNYLRTHPLLIRRNLASPEGTLATLGLKTEKNIADKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVTKMSSLTAKKDPLDFTSERMENGPSKSGALNDGSGSSGAAWSAKASSQFDWSQPIVTVDEEPLQLDWGEDHDSALEEDDTGGLVMKSTDVKKDGQDHKASDHSALLTPQEEDCVLGDSEVDVIAEQLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEICNHESVIKEYSSKTYSKVESELLDHEEMVDKPDIGSYERHQIERRRLQAKREHAERRKLWLQKNQDLLRVFLSYCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIANPVLYLNNHIHDILYTIVQMKTPPHPNVEDMKVHTLHSLAASLSASIYQALCDSHSYSQTEGNQFTGMAYQGLLLSDRRRLRTESIEEHATPNSAPAQWPGVSSLINLLSSAQDEDQPKLNVLLCEAVVAVYLSLLIHALATNSSNELFRLAAHPLNNRMWAAVFGGGVKLVVKPRRQSESIAAPPVPSEDIDKHRRRFNMRMLVPGRPVKDATPPPVPAERPSYKEKFISPELSMWDYFIAKPFLPLSDSGVIYDSDESVHSDDEEDDAFFSDTQIQEHQDPNSYSWALLHLTMVKLALHNIKNFFPIAGLEFSELPVTSPLGIAVIKNLENWEQILQEKMDRFEGPPPNYVNTYPTDLSVGAGPAILRNKAMLEPENTPFKSRDASALPVKRLWHFLVKQEVLQETFIRYIFTKKRKQSEVEADLGYPGGKAKVIHKESDMIMAFSINKANSNEIVLASTHDVQELDVTSLLACQSYIWIGEEYDRESKSSDDIDYRGSTTTLYQPGAASHSTSQVHPPPSLPWLGSGQTSTGATVLMKRNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGQSNDNRNVCFWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGYICIFDIRQRQLLHTFQAHDSAIKALALDPCEEYFTTGSAEGNIKVWRLTGHGLIHSFKNEHAKQSIFRNIGAGVMQIDISQDNRLFSCGADGTLKTRVLPSAFNIPNRILDIL", "length": 2362, "header": "tr|A0A9J7JXZ0-1|A0A9J7JXZ0_CRIGR Computationally mapped isoform of DmX-like protein 2 isoform X6 OS=Cricetulus griseus OX=10029 GN=Dmxl2 PE=4 SV=1 CANONICAL=A0A8C2LKW5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K5C9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKW5/entry#A0A9J7K5C9-1", "sequence": { "sequence": "MHLHQVLTGAVNPGDNCYSVGSVGDVPFTAYGSGCDIVILASDFECVQIIPGAKHGNIQVSCVECSNQHGRVAASYGNAVCIFEPLGINSHKRNSQLKCQWLKTGQFFLSSVTYNLAWDPQDNRLLTATDAIQLWAPPGSDILEEEEEVDNKIPPVLNDWKCIWQCKTSVSVHLMEWSPDGEYFATAGKDDCLLKVWYPMTGWKSSIIPQDHHEVKRRQASTQFSFVYLAHPRAVTGFSWRKTSKYMPRGSVCNVLLTSCHDGVCRLWAETLLPEDCLLGEQICETTTSSITSNLSHAGKHKDRIQHALETIHHLKNLRKGQRRSSVLVTHTELMPDKTATHEVQRHISHHANALCHFHIAASINPATELSLDRESEAGTGSSEHEDGEREGSPRTHPGHSIAVPLPTVLLDRKIETLLTEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIFRQVQVSFSSRIPVAFPSGDANSLSKNIMMYACVNATKDSYHTSSHQELMSVDSSHGSQPHSRLHSTDMNILAPTVMMVSKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCGHRFHLNDLACHSVLPLLLTSSHHNALLTPESDCQWDSDSKVNRLIDPVKHTKESLKQPLRNAATRTFHDPNAIYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASACFVASDGKNLRLYQAVVDARKLLDELSDPEASKLIGEVFNIVSQQSTARPGCIIELDAITDQCGSNTQLLHVFQEDFIIGYKPHKDDTEKKKKETEIFFQPSQGYRPPPFSEKFFLVVIEKDSNNNSVLHMWHLHLKSVQACLAKVTEGISTDNLLSVPGQKKVDSSPETSPSVSSMPHSLSIANLQTASKLILSSRLVYSQPLDLPEAVEVIRATPSAGHLSSSSIYPVCLAPYLVVTTCSDNKVRFWKCCMETNTLCSISDEKETYHWRRWPLMNDEGEDNSSTVSIVGRPVAVSCSYTGRLAVAYKQPVHHNGFISKEFSMHVCIFECESTGGSEWVLEQTIHLDDLVKVGSVLDSRVSVDSNLFVYSKSDAFLSKDRYLIPNIKHLVHLDWVSKEDGSHILTVGVGANIFMYGRLSGIVTDQTNSKDGGVAVITLPLGGSIKQGVRSRWVLLRSIDLVSSVDGTPSLPVSLSWVRDGILVVGMDCEMHVYAQWKHSVKFGDIEADSPVEETVIQDHSTFKSTMLPRKSIVEGATITDDVFGSPTVVQDGGLFEAAHALSPTLPQYHPTQLLELMDLGKVRRAKAILSHLVKCIAGEVAIVRDPDAGEGTKRHLSRTISVSGSTAKDTVTIGKDGARDYTEIDSIPPLPLHALLAADQDTSYRISEESTKKPQSYEAHIESQPGDQYSELFQVQEITTDDIDLEPEKRENKSKVINLSQYGPAYFGQEHARVLSSHLMHSSLPGLTRLEQMFLVALADTVATTSTELDENRDKYSGRDTLDECGLRYLLAMRLHTCLLTSLPPLYRAQLLHQGVSTCHFAWAFHSEAEEELINMIPAIQRGDPQWSELRAMGIGWWVRNVNTLRRCIEKVAKASFQRNNDALDAALFYLSMKKKAVVWGLFRSQHDEKMTTFFSHNFNEDRWRKAALKNAFSLLGKQRFEQSAAFFLLAGSLKDAIEVCLEKMEDIQLAMVIARLFESEFETSSTYISILNQKILGREKDGSEFNCKRLHADPFLRSLAYWVMKDYTRALDTLLEQTPKEDDEQQVIIKSCNPVVFSFYNYLRTHPLLIRRNLASPEGTLATLGLKTEKNIADKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVTKMSSLTAKKDPLDFTSERMENGPSKSGALNDGSGSSGAAWSAKASSQFDWSQPIVTVDEEPLQLDWGEDHDSALEEDDTGGLVMKSTDVKKDGQDHKASDHSALLTPQEEDCVLGDSEVDVIAEQLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEICNHESVIKEYSSKTYSKVESELLDHEEMVDKPDIGSYERHQIERRRLQAKREHAERRKLWLQKNQDLLRVFLSYCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIANPVLYLNNHIHDILYTIVQMKTPPHPNVEDMKVHTLHSLAASLSASIYQALCDSHSYSQTEGNQFTGMAYQGLLLSDRRRLRTESIEEHATPNSAPAQWPGVSSLINLLSSAQDEDQPKLNVLLCEAVVAVYLSLLIHALATNSSNELFRLAAHPLNNRMWAAVFGGGVKLVVKPRRQSESIAAPPVPSEDIDKHRRRFNMRMLVPGRPVKDATPPPVPAERPSYKEKFISPELSMWDYFIAKPFLPLSDSGVIYDSDESVHSDDEEDDAFFSDTQIQEHQDPNSYSWALLHLTMVKLALHNIKNFFPIAGLEFSELPVTSPLGIAVIKNLENWEQILQEKMDRFEGPPPNYVNTYPTDLSVGAGPAILRNKAMLEPENTPFKSRDASALPVKRLWHFLVKQEVLQETFIRYIFTKKRKQSEVF", "length": 2561, "header": "tr|A0A9J7K5C9-1|A0A9J7K5C9_CRIGR Computationally mapped isoform of DmX-like protein 2 isoform X4 OS=Cricetulus griseus OX=10029 GN=Dmxl2 PE=4 SV=1 CANONICAL=A0A8C2LKW5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1248, "start_aa": "Thr", "end_pos": 1248, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1248", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LKW5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKW5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LKW5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKW5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753187", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753187", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "RAVE complex", "id": "GO:0043291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043291", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LKW5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKW5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "vacuolar acidification", "id": "GO:0007035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007035", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LKW5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LKW5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1063, "end_pos": 1065, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1493, "end_pos": 1495, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1499, "end_pos": 1501, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2360, "end_pos": 2362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2855, "end_pos": 2857, "annotation": "n_glycosylation_sequon" }, { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 569, "end_pos": 571, "annotation": "n_glycosylation_sequon" }, { "start_pos": 905, "end_pos": 907, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027256149", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256149" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LL06", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LL06" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100766144", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LL06", "locus": {} } ], "crossref": [ { "id": "cd00095", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00095", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100766144", "url": "https://www.ncbi.nlm.nih.gov/gene/100766144", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000471", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000471", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766144", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766144", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LL06", "url": "https://www.orthodb.org/?gene=A0A8C2LL06", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11691", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11691", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11691:SF60", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11691:SF60", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00143", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00143", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027256149", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256149", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LL06", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LL06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LL06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LL06-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARLCAFLLALVVMSYWSTCFLGCDLPQTHNIRNKRALTLLAQMRRLSPLSCLKDRKDFAFPLENMDAQHIQKAQAIPILQELIQQVLILFSSKDSSATWETTLLDTFCTGLHQQLSDLQACLMQQVGEQEPPLSQEDSLVAVRKYFHRITAYLREKNHSPCAWEVVRAEVWRALSSSANLLARLSEEKE", "length": 190, "header": "tr|A0A8C2LL06-1|A0A8C2LL06_CRIGR Isoform 1 of Interferon alpha-12 OS=Cricetulus griseus OX=10029 GN=LOC100766144 PE=3 SV=1 CANONICAL=A0A8C2LL06-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LL06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LL06/entry#A0A8C2LL06-1", "sequence": { "sequence": "MARLCAFLLALVVMSYWSTCFLGCDLPQTHNIRNKRALTLLAQMRRLSPLSCLKDRKDFAFPLENMDAQHIQKAQAIPILQELIQQVLILFSSKDSSATWETTLLDTFCTGLHQQLSDLQACLMQQVGEQEPPLSQEDSLVAVRKYFHRITAYLREKNHSPCAWEVVRAEVWRALSSSANLLARLSEEKE", "length": 190, "header": "tr|A0A8C2LL06-1|A0A8C2LL06_CRIGR Isoform 1 of Interferon alpha-12 OS=Cricetulus griseus OX=10029 GN=LOC100766144 PE=3 SV=1 CANONICAL=A0A8C2LL06-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027243187", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243187" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LLE9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLE9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Crisp2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLE9", "locus": {} } ], "crossref": [ { "id": "cd05383", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05383", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100764099", "url": "https://www.ncbi.nlm.nih.gov/gene/100764099", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001283", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001283", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002413", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002413", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003582", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003582", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013871", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013871", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034117", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034117", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042076", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042076", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764099", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764099", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CTNSCEF", "url": "https://omabrowser.org/oma/group/CTNSCEF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LLE9", "url": "https://www.orthodb.org/?gene=A0A8C2LLE9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10334", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10334", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00188", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00188", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027243187", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027243187", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LLE9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LLE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLE9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAS8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAS8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HAS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HAS8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGWFQVMLLLFALLLQSMPSEGKDPAFTALLTNQPQVQLEIVGKHNELRRAVNPTASNMLRMEWNVEVAGNAQKWANKCTLEHSNAEDRKIKTRCGENLYMSSDPTPWTTAIQSWYDESENFTYGVGAKPNTAVGHFTQVVWYSTYKVGCGIAFCPNQDTLKYFYVCQYCPAGNNVLKKSTPYQQGLPCASCPNNCDKGLCTNSCEFEDNLSNCESLKSSAGCEHELLKEKCQATCLCEGKIY", "length": 243, "header": "tr|A0A8C2LLE9-1|A0A8C2LLE9_CRIGR Isoform 1 of Cysteine-rich secretory protein 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Crisp2 PE=3 SV=1 CANONICAL=A0A8C2LLE9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LLE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLE9/entry#A0A8C2LLE9-1", "sequence": { "sequence": "MGWFQVMLLLFALLLQSMPSEGKDPAFTALLTNQPQVQLEIVGKHNELRRAVNPTASNMLRMEWNVEVAGNAQKWANKCTLEHSNAEDRKIKTRCGENLYMSSDPTPWTTAIQSWYDESENFTYGVGAKPNTAVGHFTQVVWYSTYKVGCGIAFCPNQDTLKYFYVCQYCPAGNNVLKKSTPYQQGLPCASCPNNCDKGLCTNSCEFEDNLSNCESLKSSAGCEHELLKEKCQATCLCEGKIY", "length": 243, "header": "tr|A0A8C2LLE9-1|A0A8C2LLE9_CRIGR Isoform 1 of Cysteine-rich secretory protein 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Crisp2 PE=3 SV=1 CANONICAL=A0A8C2LLE9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HAS8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLE9/entry#A0A9J7HAS8-1", "sequence": { "sequence": "MGWFQVMLLLFALLLQSMPSEGKEWNVEVAGNAQKWANKCTLEHSNAEDRKIKTRCGENLYMSSDPTPWTTAIQSWYDESENFTYGVGAKPNTAVGHFTQVVWYSTYKVGCGIAFCPNQDTLKYFYVCQYCPAGNNVLKKSTPYQQGLPCASCPNNCDKGLCTNSCEFEDNLSNCESLKSSAGCEHELLKEKCQATCLCEGKIY", "length": 204, "header": "tr|A0A9J7HAS8-1|A0A9J7HAS8_CRIGR Computationally mapped isoform of Cysteine-rich secretory protein 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Crisp2 PE=3 SV=1 CANONICAL=A0A8C2LLE9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 106, "start_aa": "Thr", "end_pos": 106, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr106", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 55, "start_aa": "Thr", "end_pos": 55, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr55", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LLE9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLE9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LLE9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLE9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764099", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764099", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1N2L7-1", "protein_name": "Cysteine rich secretory protein 2", "gene_name": "CRISP2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MALLPVVLFLTAVLLPSFPTEGKDPSFTALITTQTQVQREIVNKHNELRKSVSPPASNMLKMEWSREVTANAQKWANKCTLEHSSPNERKTSTKCGENLYMSSDPTAWSDAIQSWFNEHHDFIYGSGPKSTGAIVGHYTQLVWYSSFRVGCGIAYCPNQESLKYYYVCQYCPAGNNVSKKNTPYQQGAPCGSCPGNCDNGLCTNTCEYEDLLSNCDSLKKTAGCEHELLKEKCKATCLCEGKIY", "length": 244 }, "evidence": [ { "id": "A0A8C2LLE9", "url": "https://omabrowser.org/oma/group/A0A8C2LLE9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RPZ6-1", "protein_name": "Cysteine rich secretory protein 2", "gene_name": "CRISP2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALLPMVLFLAAVLLPSFPTEGKDPSFTALLTSQPQIQKEIVAKHNELRRSVSPPASNMLKMEWSRETSANAQKWANKCTLEHSNPDDRKTSTKCGENLYMSSDPAAWSDAIQSWFDERHDFVYGAGPKSSSAVVGHYTQLVWYSSYRVGCGIAYCPNQENLKYYYVCQYCPAGNNVSKKNTPYKEGTPCASCPGDCDDGLCTNTCQYEDLLSNCDSLKKTAGCGHELLKEKCKATCLCEGKIY", "length": 244 }, "evidence": [ { "id": "A0A8C2LLE9", "url": "https://omabrowser.org/oma/group/A0A8C2LLE9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O88205-1", "protein_name": "Cysteine-rich secretory protein 2", "gene_name": "Crisp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAWFQVMLFVFAVLLPLPPTEGKDPDFATLTTNQIQVQREIIAKHNELRRQVSPPGSNILKMEWNVQAAANAQKWANNCILEHSSTEDRKINIKCGENLYMSTDPTSWRTVIQSWYEENENFVFGVGAKPNSAVGHYTQLVWYSSFKVGCGVAYCPNQDTLKYFYVCHYCPMGNNVMKKSTPYHQGTPCASCPNNCDNGLCTNSCDFEDLLSNCESLKSSAGCKHELLKAKCEATCLCEDKIH", "length": 243 }, "evidence": [ { "id": "A0A8C2LLE9", "url": "https://omabrowser.org/oma/group/A0A8C2LLE9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P16562-1", "protein_name": "Cysteine-rich secretory protein 2", "gene_name": "CRISP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALLPVLFLVTVLLPSLPAEGKDPAFTALLTTQLQVQREIVNKHNELRKAVSPPASNMLKMEWSREVTTNAQRWANKCTLQHSDPEDRKTSTRCGENLYMSSDPTSWSSAIQSWYDEILDFVYGVGPKSPNAVVGHYTQLVWYSTYQVGCGIAYCPNQDSLKYYYVCQYCPAGNNMNRKNTPYQQGTPCAGCPDDCDKGLCTNSCQYQDLLSNCDSLKNTAGCEHELLKEKCKATCLCENKIY", "length": 243 }, "evidence": [ { "id": "A0A8C2LLE9", "url": "https://omabrowser.org/oma/group/A0A8C2LLE9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P16563-1", "protein_name": "Cysteine-rich secretory protein 2", "gene_name": "Crisp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAWFQVMLFVFALLLRSPLTEGKDPDFTSLLTNQLQVQREIVNKHNELRRSVNPTGSDILKMEWSIQATTNAQKWANKCILEHSSKDDRKINIRCGENLYMSTDPTLWSTVIQSWYNENEDFVYGVGAKPNSAVGHYTQLVWYSSFKIGCGIAYCPNQDNLKYFYVCHYCPMGNNVMKKSTPYQQGTPCASCPNNCENGLCTNSCDFEDLLSNCESLKTSAGCKHELLKTKCQATCLCEDKIH", "length": 243 }, "evidence": [ { "id": "A0A8C2LLE9", "url": "https://omabrowser.org/oma/group/A0A8C2LLE9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LLE9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLE9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LLE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLE9" }, { "id": "PS51670", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51670" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ShKT", "eco_id": "ECO_0000259", "start_pos": 205, "end_pos": 238, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 55, 106 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 }, { "start_pos": 210, "end_pos": 212 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LLG0-1", "uniprot_ac": "A0A8C2LLG0", "uniprot_id": "A0A8C2LLG0_CRIGR", "mass": { "chemical_mass": 41019.0, "monoisotopic_mass": 41019.0 }, "refseq": { "ac": "XP_027263560", "name": "trophoblast glycoprotein-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263560" }, "gene_names": [ { "name": "LOC113834878", "type": "recommended", "evidence": [ { "id": "A0A8C2LLG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLG0" } ] }, { "name": "LOC113834878", "type": "synonym", "evidence": [ { "id": "XP_027263560", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027263560" } ] } ], "protein_names": [ { "name": "Trophoblast glycoprotein-like", "type": "synonym", "evidence": [ { "id": "A0A8C2LLG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLG0/entry#names_and_taxonomy" } ] }, { "name": "trophoblast glycoprotein-like", "type": "synonym", "evidence": [ { "id": "XP_027263560", "database": "RefSeq", "url": 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This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. 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Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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"url": "https://www.uniprot.org/uniprotkb/A0A8C2LLJ8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LLJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLJ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "lipid homeostasis", "id": "GO:0055088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055088", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LLJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLJ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LLJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLJ8" }, { "id": "PS50922", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50922" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TLC", "eco_id": "ECO_0000259", "start_pos": 33, "end_pos": 249, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LLV6-1", "uniprot_ac": "A0A8C2LLV6", "uniprot_id": "A0A8C2LLV6_CRIGR", "mass": { "chemical_mass": 35076.0, "monoisotopic_mass": 35076.0 }, "refseq": { "ac": "XP_003506537", "name": "ester hydrolase C11orf54 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506537" }, "gene_names": [ { "name": "CUNH11orf54", "type": "recommended", "evidence": [ { "id": "A0A8C2LLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLV6" } ] }, { "name": "CUNH11orf54", "type": "synonym", "evidence": [ { "id": "XP_003506537", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506537" } ] } ], "protein_names": [ { "name": "Ester hydrolase C11orf54 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8C2LLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLV6/entry#names_and_taxonomy" } ] }, { "name": "ester hydrolase C11orf54 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003506537", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506537" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614246.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003506537", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506537" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LLV6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLV6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "CUNH11orf54", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLV6", "locus": {} } ], "crossref": [ { "id": "cd17298", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17298", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100753132", "url": "https://www.ncbi.nlm.nih.gov/gene/100753132", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR015021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753132", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753132", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YHIMPDF", "url": "https://omabrowser.org/oma/group/YHIMPDF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LLV6", "url": "https://www.orthodb.org/?gene=A0A8C2LLV6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13204", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13204", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13204:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13204:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08925", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08925", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003506537", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506537", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LLV6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LLV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLV6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K7X0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7X0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K7X0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K7X0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MACIEFSFHVPSLEELAEVLQKGLKDNFADVQVSVVDCPDLTKEPFTFPVKGICGQTRIAEVGGVPYLMPLANKTKVYDLNEIAKEIKLPGAFILGAGAGPFQTLGFNSEFMPIVQTASENNRPVNESYFARINPADGSCLLEKYSQKYHDFGCALLANLFASEGQPGKVIEVQAKRRTGQLNFVTCMRQTLEKHYGNKPVGMGGTFIVQKGNVKAHIMPAEFSSCPLNSDEAVNKWLHFYEMKAPLVCLPVFVSKDPGLDLRLEHTHFFSHHGEGGHYHYDTTPDTVEYLGYFSPAQFLYRIDQPKETHAFGRD", "length": 315, "header": "tr|A0A8C2LLV6-1|A0A8C2LLV6_CRIGR Isoform 1 of Ester hydrolase C11orf54 homolog isoform X1 OS=Cricetulus griseus OX=10029 GN=CUNH11orf54 PE=4 SV=1 CANONICAL=A0A8C2LLV6-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LLV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLV6/entry#A0A8C2LLV6-1", "sequence": { "sequence": "MACIEFSFHVPSLEELAEVLQKGLKDNFADVQVSVVDCPDLTKEPFTFPVKGICGQTRIAEVGGVPYLMPLANKTKVYDLNEIAKEIKLPGAFILGAGAGPFQTLGFNSEFMPIVQTASENNRPVNESYFARINPADGSCLLEKYSQKYHDFGCALLANLFASEGQPGKVIEVQAKRRTGQLNFVTCMRQTLEKHYGNKPVGMGGTFIVQKGNVKAHIMPAEFSSCPLNSDEAVNKWLHFYEMKAPLVCLPVFVSKDPGLDLRLEHTHFFSHHGEGGHYHYDTTPDTVEYLGYFSPAQFLYRIDQPKETHAFGRD", "length": 315, "header": "tr|A0A8C2LLV6-1|A0A8C2LLV6_CRIGR Isoform 1 of Ester hydrolase C11orf54 homolog isoform X1 OS=Cricetulus griseus OX=10029 GN=CUNH11orf54 PE=4 SV=1 CANONICAL=A0A8C2LLV6-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K7X0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLV6/entry#A0A9J7K7X0-1", "sequence": { "sequence": "MHAVLQKGLKDNFADVQVSVVDCPDLTKEPFTFPVKGICGQTRIAEVGGVPYLMPLANKTKVYDLNEIAKEIKLPGAFILGAGAGPFQTLGFNSEFMPIVQTASENNRPVNESYFARINPADGSCLLEKYSQKYHDFGCALLANLFASEGQPGKVIEVQAKRRTGQLNFVTCMRQTLEKHYGNKPVGMGGTFIVQKGNVKAHIMPAEFSSCPLNSDEAVNKWLHFYEMKAPLVCLPVFVSKDPGLDLRLEHTHFFSHHGEGGHYHYDTTPDTVEYLGYFSPAQFLYRIDQPKETHAFGRD", "length": 300, "header": "tr|A0A9J7K7X0-1|A0A9J7K7X0_CRIGR Computationally mapped isoform of Ester hydrolase C11orf54 homolog isoform X2 OS=Cricetulus griseus OX=10029 GN=CUNH11orf54 PE=4 SV=1 CANONICAL=A0A8C2LLV6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LLV6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLV6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LLV6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLV6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753132", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753132", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QPP0-1", "protein_name": "Chromosome 9 C11orf54 homolog", "gene_name": "C9H11orf54", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MACAEYSFHVPSLEELVGVLQKGLKDNFADVQVSVVDCPDLTKEPFTFPVKGICGKPRIAEVGGVPYLLPLVNKKKVYDLNKIAKEIQLPGAFILGAGAGPFQTLGFSSEFMPVIQTECEHKPPVNGSYFARVNPEDGGCLLEKYSEKYHDFGCALLANLFASEGQPGKPAEFSVCPLNSDEEVNNWLRFYEMKAPLVCLPVFVSRDPGFDLRLEHTHCFSHHGEGGHYHYDTTPDTVEYLGYFLPAEFLYRIDQPKETHLFGRD", "length": 265 }, "evidence": [ { "id": "A0A8C2LLV6", "url": "https://omabrowser.org/oma/group/A0A8C2LLV6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q2HJH3-1", "protein_name": "Beta-keto L-gulonate decarboxylase", "gene_name": "C29H11orf54", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MACAEYSFHVPSLEELVGVLQKGLTDNFAEVQVSVVDCPDLTKEPFTFPIKGICGKTRIAEVGGVPYLLPLVNEKKVYDLNKIAKDIQLPGAFVLGAGAGPFQTLGFNSEFMLLVQTESEHRPPVNGSYFARVNPADGGCLLEKYSEKYHDFGCALLANLFASEGQPGKVIEVKVKRRTGKLNFVTCMRQTLEKHYGDKPVGMGGAFIIQKGKVKTHIMPAEFSSCPLNSDEDVNKWLHFYEMKAPLVCLPVFVSRDPGFDLRLEHTHCFSHHGEGGHYHYDTTPDIVEYLGYFLPAEFLYRIDQPKETHSFGRD", "length": 315 }, "evidence": [ { "id": "A0A8C2LLV6", "url": "https://omabrowser.org/oma/group/A0A8C2LLV6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6NWE0-1", "protein_name": "Ester hydrolase C11orf54 homolog", "gene_name": "", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDNSGKTEKFQLHVPNLEELCQVLESGLNKNFSDVKVSVTDCPDLTQQPFGFPVKGLCGKPRITDVGGVPNLIPLVKLDKVYNMNSVSKEVELPGAFILGAGAISFKTAGINGELMPLVLTEAEGRSAVNASYFSSINPEDGKCLQEKYSDRFDDCDFGLLANLYACEGKPGKVIEVKACRRTGEDSLVSCMRKTMAEHYGEKSVALGGTFIIQKGKAKIHIMPREFSVCPLNTDEDVNNWLRHFEVSAPLIFQTVMISRDPGLDLRVEHTHGFSHHGEGGHYYTDTTPNTVEYLGYFLPAETVYRIDRPTETHNVGRD", "length": 319 }, "evidence": [ { "id": "A0A8C2LLV6", "url": "https://omabrowser.org/oma/group/A0A8C2LLV6/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q91V76-1", "protein_name": "Beta-keto L-gulonate decarboxylase", "gene_name": "Bkgd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MACSEFSFHMPSLEELAEVLQKGLTDNFADVQVSVVDCPDLTKEPFTFPVRGICGQTRIAEVGGVPYLLPLVNKKKVYDLNEIAKVIKLPGAFILGAGAGPFQTLGFNSEFMPIVQTASEHNQPVNGSYFAHKNPADGACLLEKYSQKYHDFGCALLANLFASEGQPGKVIEVQAKRRTGELNFVSCMRQTLEEHYGDKPVGMGGTFIVQKGKVKAHIMPAEFSSCPLNSDEAVNKWLHFYEMKAPLVCLPVFVSKDPGLDLRLEHTHFFSHHGEGGHYHYDTTPDTVEYLGYFSPAQFLYRIDQPKETHAFGRD", "length": 315 }, "evidence": [ { "id": "A0A8C2LLV6", "url": "https://omabrowser.org/oma/group/A0A8C2LLV6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H0W9-1", "protein_name": "Beta-keto L-gulonate decarboxylase", "gene_name": "BKGD", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MACAEFSFHVPSLEELAGVMQKGLKDNFADVQVSVVDCPDLTKEPFTFPVKGICGKTRIAEVGGVPYLLPLVNQKKVYDLNKIAKEIKLPGAFILGAGAGPFQTLGFNSEFMPVIQTESEHKPPVNGSYFAHVNPADGGCLLEKYSEKCHDFQCALLANLFASEGQPGKVIEVKAKRRTGPLNFVTCMRETLEKHYGNKPIGMGGTFIIQKGKVKSHIMPAEFSSCPLNSDEEVNKWLHFYEMKAPLVCLPVFVSRDPGFDLRLEHTHFFSRHGEGGHYHYDTTPDIVEYLGYFLPAEFLYRIDQPKETHSIGRD", "length": 315 }, "evidence": [ { "id": "A0A8C2LLV6", "url": "https://omabrowser.org/oma/group/A0A8C2LLV6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W0J9-1", "protein_name": "DUF1907 domain-containing protein", "gene_name": "CT9987", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSQNQLSTEQLLFEEKPLYVPPLSELQNVIQGALAANFANVNVSVGPCPDLKAKQFGLVESGLGGKPTLLEAGGPPFLLPLVQRDKLYNIAEITRKIQGPGTVFAVGAGAGPWPIRGSNCEGIFNLSVNEKDELTNGSYTATVRGEQEECVLEKIPHTEPRCALLLNLFLSQGKPGQVLKITAKQRTGEQNFIECIRKGLENHYGDKVVGLGGIFLIKKGAAHQHVMRDFSKTPINSDEEVNEWLKFYEMPAQLNAVGTLVTKEHDLDLRLQHFHSFSFSNWGGHYHYDTTPDIVEYEAYLNVAERVVRVDKPVATHKVGRD", "length": 322 }, "evidence": [ { "id": "A0A8C2LLV6", "url": "https://omabrowser.org/oma/group/A0A8C2LLV6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LLV6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLV6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LLV6", 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This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307215", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307215" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LLX5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLX5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113833093", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLX5", "locus": {} } ], "crossref": [ { "id": "113833093", "url": "https://www.ncbi.nlm.nih.gov/gene/113833093", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028205", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028205", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113833093", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113833093", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PF14672", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14672", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307215", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307215", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LLX5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LLX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLX5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSCQQNQQQCQPPPKCPPKCPPKCQTTKCPPKCPPKCPPKCPPVSSCCSLGSGGCCGSSSGGCCGSSSGGCCSSGSGGCCLSHHRPRRSLRRHRHSSGCCSSGGSSGCCGSSGGSSCGSSGCCGSSGGSSCGSSQQSGGCC", "length": 141, "header": "tr|A0A8C2LLX5-1|A0A8C2LLX5_CRIGR Isoform 1 of Late cornified envelope protein 1B-like OS=Cricetulus griseus OX=10029 GN=LOC113833093 PE=3 SV=1 CANONICAL=A0A8C2LLX5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LLX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LLX5/entry#A0A8C2LLX5-1", "sequence": { "sequence": "MSCQQNQQQCQPPPKCPPKCPPKCQTTKCPPKCPPKCPPKCPPVSSCCSLGSGGCCGSSSGGCCGSSSGGCCSSGSGGCCLSHHRPRRSLRRHRHSSGCCSSGGSSGCCGSSGGSSCGSSGCCGSSGGSSCGSSQQSGGCC", "length": 141, "header": "tr|A0A8C2LLX5-1|A0A8C2LLX5_CRIGR Isoform 1 of Late cornified envelope protein 1B-like OS=Cricetulus griseus OX=10029 GN=LOC113833093 PE=3 SV=1 CANONICAL=A0A8C2LLX5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. 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Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614139.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003505350", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505350" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LMP6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMP6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100765929", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMP6", "locus": {} } ], "crossref": [ { "id": "100765929", "url": "https://www.ncbi.nlm.nih.gov/gene/100765929", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765929", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765929", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LMP6", "url": "https://www.orthodb.org/?gene=A0A8C2LMP6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24232", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24232", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24232:SF83", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24232:SF83", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003505350", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003505350", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LMP6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LMP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMP6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKDLRRYLVFKYIQYLVLPSPNTIITLLGLLASLYVMLILTFPSVSRKSTVVFISNIAQADILAGCSIFSAITAGMIKSETSSASFQSGLRQNFQIANVHASSLLLSCVSLEAFLITFLPVETRHIRNVRCARVASKIIWAAVITECFLYQLECIKCLNVSHRQVQLLMNFCHDTTAWLKLLIYPIGILLRIFNIYLFYKMYF", "length": 203, "header": "tr|A0A8C2LMP6-1|A0A8C2LMP6_CRIGR Isoform 1 of P2Y purinoceptor 6-like OS=Cricetulus griseus OX=10029 GN=LOC100765929 PE=4 SV=1 CANONICAL=A0A8C2LMP6-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LMP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMP6/entry#A0A8C2LMP6-1", "sequence": { "sequence": "MKDLRRYLVFKYIQYLVLPSPNTIITLLGLLASLYVMLILTFPSVSRKSTVVFISNIAQADILAGCSIFSAITAGMIKSETSSASFQSGLRQNFQIANVHASSLLLSCVSLEAFLITFLPVETRHIRNVRCARVASKIIWAAVITECFLYQLECIKCLNVSHRQVQLLMNFCHDTTAWLKLLIYPIGILLRIFNIYLFYKMYF", "length": 203, "header": "tr|A0A8C2LMP6-1|A0A8C2LMP6_CRIGR Isoform 1 of P2Y purinoceptor 6-like OS=Cricetulus griseus OX=10029 GN=LOC100765929 PE=4 SV=1 CANONICAL=A0A8C2LMP6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LMP6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMP6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LMP6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMP6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765929", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765929", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LMP6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMP6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LMP6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMP6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "phospholipase C-activating G protein-coupled receptor signaling pathway", "id": "GO:0007200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007200", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LMP6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMP6" } ], "pmid": "" }, { "name": "positive regulation of Rho protein signal transduction", "id": "GO:0035025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035025", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LMP6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMP6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LMP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMP6" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 203, "start_aa": "Ala", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 159, "end_pos": 161 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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"o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LMQ7-1", "uniprot_ac": "A0A8C2LMQ7", "uniprot_id": "A0A8C2LMQ7_CRIGR", "mass": { "chemical_mass": 16165.0, "monoisotopic_mass": 16165.0 }, "refseq": { "ac": "XP_007640752", "name": "transmembrane protein 207", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640752" }, "gene_names": [ { "name": "Tmem207", "type": "recommended", "evidence": [ { "id": "A0A8C2LMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMQ7" } ] }, { "name": "Tmem207", "type": "synonym", "evidence": [ { "id": "XP_007640752", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640752" } ] } ], "protein_names": [ { "name": "Transmembrane protein 207", "type": "synonym", "evidence": [ { "id": "A0A8C2LMQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMQ7/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 207", "type": "synonym", "evidence": [ { "id": "XP_007640752", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640752" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007640752", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640752" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LMQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMQ7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tmem207", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMQ7", "locus": {} } ], "crossref": [ { "id": "100751504", "url": "https://www.ncbi.nlm.nih.gov/gene/100751504", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR039490", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039490", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751504", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751504", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PNGWYIW", "url": "https://omabrowser.org/oma/group/PNGWYIW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LMQ7", "url": "https://www.orthodb.org/?gene=A0A8C2LMQ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR36467", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36467", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR36467:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36467:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14979", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14979", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007640752", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007640752", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LMQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LMQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRSSPFRVTSKIPTTGSLCLPLFQLVLSDVSCEENETCVNYNDQHPDAWYIWFLLWIFLVVLLCGIVLLCLRCWLKRCRIDHPRRTMAVFAIGDLDLIHGTEMAGNPSVRISLPTPNTELCPALRFGDLGPPPPYEETLKTS", "length": 143, "header": "tr|A0A8C2LMQ7-1|A0A8C2LMQ7_CRIGR Isoform 1 of Transmembrane protein 207 OS=Cricetulus griseus OX=10029 GN=Tmem207 PE=4 SV=1 CANONICAL=A0A8C2LMQ7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LMQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMQ7/entry#A0A8C2LMQ7-1", "sequence": { "sequence": "MSRSSPFRVTSKIPTTGSLCLPLFQLVLSDVSCEENETCVNYNDQHPDAWYIWFLLWIFLVVLLCGIVLLCLRCWLKRCRIDHPRRTMAVFAIGDLDLIHGTEMAGNPSVRISLPTPNTELCPALRFGDLGPPPPYEETLKTS", "length": 143, "header": "tr|A0A8C2LMQ7-1|A0A8C2LMQ7_CRIGR Isoform 1 of Transmembrane protein 207 OS=Cricetulus griseus OX=10029 GN=Tmem207 PE=4 SV=1 CANONICAL=A0A8C2LMQ7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LMQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMQ7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LMQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMQ7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751504", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751504", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "I3LQ19-1", "protein_name": "Transmembrane protein 207", "gene_name": "TMEM207", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLRPRLLSVTSLISKPGILCLPLFQLVLSDSPCEENEMCINYKDQYTNGWYIWFLLLIFLVALHCGAVLFCLQCWVRRSQNCSPRRTVAVFAVGDLDPVYGTEAAVNPTAGTHLQIQNTELYRVPCFGTLGPPPPYEEIPKSSRF", "length": 145 }, "evidence": [ { "id": "A0A8C2LMQ7", "url": "https://omabrowser.org/oma/group/A0A8C2LMQ7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M0R975-1", "protein_name": "Transmembrane protein 207", "gene_name": "Tmem207", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRSSPFRVGSKIPTMGYLCLPLFQLALSNLSCEDNEMCVNYDEQYPDGWSIWLLLLTVVVVLLCGVVLFCLQCWLKSCGTDRPRRTMAVFAVGDLDPVYGAEMAGSPTAGICLPTQNTELCPAPSLGALGPPPPYEEILKTN", "length": 143 }, "evidence": [ { "id": "A0A8C2LMQ7", "url": "https://omabrowser.org/oma/group/A0A8C2LMQ7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P86045-1", "protein_name": "Transmembrane protein 207", "gene_name": "Tmem207", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTSSPFRVASKIVTAGCLCLPLFQRVLSDLSCEENEMCVNYDERYPDGWYIWFFLLIFLVVLLCGVVLFCLQCWLKRCGINPPRRTMAVFAVGDLDPVYGAEMAGSPTSGICHPTQNTELCSAPCFGALGPPPPYEEILKAN", "length": 143 }, "evidence": [ { "id": "A0A8C2LMQ7", "url": "https://omabrowser.org/oma/group/A0A8C2LMQ7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6UWW9-1", "protein_name": "Transmembrane protein 207", "gene_name": "TMEM207", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRSRLFSVTSAISTIGILCLPLFQLVLSDLPCEEDEMCVNYNDQHPNGWYIWILLLLVLVAALLCGAVVLCLQCWLRRPRIDSHRRTMAVFAVGDLDSIYGTEAAVSPTVGIHLQTQTPDLYPVPAPCFGPLGSPPPYEEIVKTT", "length": 146 }, "evidence": [ { "id": "A0A8C2LMQ7", "url": "https://omabrowser.org/oma/group/A0A8C2LMQ7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "R4GII2-1", "protein_name": "Transmembrane protein 207", "gene_name": "TMEM207", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQRPRVWCFTSWITEAGVLYFIFFQPAGSQPDCEPGERCIRQNDENFSSWYVWFLTLFLLALLLSCGICCCLQCWLKRRSSLQPRTLAVFALSSSDAFCASEAPQCPFSRSPSACVNVERSSPALQLSPGGTELPPSYEDIMKENKL", "length": 147 }, "evidence": [ { "id": "A0A8C2LMQ7", "url": "https://omabrowser.org/oma/group/A0A8C2LMQ7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "early endosome membrane", "id": "GO:0031901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031901", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LMQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMQ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 36, "end_pos": 38 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LMT7-1", "uniprot_ac": "A0A8C2LMT7", "uniprot_id": "A0A8C2LMT7_CRIGR", "mass": { "chemical_mass": 65919.0, "monoisotopic_mass": 65919.0 }, "refseq": { "ac": "XP_003502170", "name": "solute carrier family 13 member 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502170" }, "gene_names": [ { "name": "Slc13a1", "type": "recommended", "evidence": [ { "id": "A0A8C2LMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMT7" } ] }, { "name": "Slc13a1", "type": "synonym", "evidence": [ { "id": "XP_003502170", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502170" } ] } ], "protein_names": [ { "name": "Solute carrier family 13 member 1", "type": "synonym", "evidence": [ { "id": "A0A8C2LMT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMT7/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 13 member 1", "type": "synonym", "evidence": [ { "id": "XP_003502170", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502170" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613878.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003502170", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502170" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LMT7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMT7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Slc13a1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMT7", "locus": {} } ], "crossref": [ { "id": "100757983", "url": "https://www.ncbi.nlm.nih.gov/gene/100757983", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001898", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001898", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031312", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031312", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757983", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757983", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "THIMAHT", "url": "https://omabrowser.org/oma/group/THIMAHT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LMT7", "url": "https://www.orthodb.org/?gene=A0A8C2LMT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10283", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10283", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10283:SF65", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10283:SF65", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00939", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00939", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003502170", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502170", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LMT7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LMT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMT7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLLNYALVYRRFLLVILSVLLLLPLPLSIRSKEAECAYVLFVVAIFWITEALPLSITALLPGLMFPMFGIMASTHVASSYFKDFHLLLIGVICLATSIEKWNLHKRIALRMVMMVGVNPAWLTLGFMSSTAFLSMWLSNTSTAAMVMPIVEAVAQQIISAEAEAEATQMTYFNESAAHGLEVDETDIGQETNERKEKTKPVPGSSNDTGKVSSKVETEKNSVTGAKYRSKRDHMLCKLMCLSIAYSSTIGGLTTLTGTSTNLIFSEHFNTRYPDCRCLNFGSWFLFSFPVAIILLLLSWIWLQWLFLGFNFKEMFKCGKTKTLKEKACAEVIKQEYEKLGPIRYQEIVTLVIFVVMALLWFSRDPGFVTGWSVLFSEYPGYVTDSTVALVAGLLFFLIPAKKLTKTTSSGEIVAFDYSPLITWKEFQSFMPWDIAILVGGGFALADGCQESGLSSWIGSKLSPLGSLPNWLIILISSLMVTSLTEVASNPATITILFPILSPLAEAIHVNPLYILLPSTLCTSFAFLLPVANPPNAIVFSYGHLKVIDMVKAGLGVNILGVAVVMLGVFTWMDSMFNLNEYPSWAPDFVNQTMP", "length": 595, "header": "tr|A0A8C2LMT7-1|A0A8C2LMT7_CRIGR Isoform 1 of Solute carrier family 13 member 1 OS=Cricetulus griseus OX=10029 GN=Slc13a1 PE=3 SV=1 CANONICAL=A0A8C2LMT7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LMT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMT7/entry#A0A8C2LMT7-1", "sequence": { "sequence": "MKLLNYALVYRRFLLVILSVLLLLPLPLSIRSKEAECAYVLFVVAIFWITEALPLSITALLPGLMFPMFGIMASTHVASSYFKDFHLLLIGVICLATSIEKWNLHKRIALRMVMMVGVNPAWLTLGFMSSTAFLSMWLSNTSTAAMVMPIVEAVAQQIISAEAEAEATQMTYFNESAAHGLEVDETDIGQETNERKEKTKPVPGSSNDTGKVSSKVETEKNSVTGAKYRSKRDHMLCKLMCLSIAYSSTIGGLTTLTGTSTNLIFSEHFNTRYPDCRCLNFGSWFLFSFPVAIILLLLSWIWLQWLFLGFNFKEMFKCGKTKTLKEKACAEVIKQEYEKLGPIRYQEIVTLVIFVVMALLWFSRDPGFVTGWSVLFSEYPGYVTDSTVALVAGLLFFLIPAKKLTKTTSSGEIVAFDYSPLITWKEFQSFMPWDIAILVGGGFALADGCQESGLSSWIGSKLSPLGSLPNWLIILISSLMVTSLTEVASNPATITILFPILSPLAEAIHVNPLYILLPSTLCTSFAFLLPVANPPNAIVFSYGHLKVIDMVKAGLGVNILGVAVVMLGVFTWMDSMFNLNEYPSWAPDFVNQTMP", "length": 595, "header": "tr|A0A8C2LMT7-1|A0A8C2LMT7_CRIGR Isoform 1 of Solute carrier family 13 member 1 OS=Cricetulus griseus OX=10029 GN=Slc13a1 PE=3 SV=1 CANONICAL=A0A8C2LMT7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LMT7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMT7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LMT7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMT7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757983", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757983", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AWR1-1", "protein_name": "Solute carrier family 13 member 1", "gene_name": "SLC13A1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKVSYVLVYRRLLLVVFTLLFLLPLPIILGTKEAECAYTLFVVAMFWLTEALPLSVTALLPGLMFPLFGIMPSKEVASAYFKDFHLLLIGVICLATSIEKWNLHKRIALRMVMTVGVNPAWLTLGFMSSTAFLSMWLSNTSTAAMVMPIVEAVAQQIINAEAEVEATQMTYFSGSTNLGLETDESVNGHETNERKEKTKPVAGYRNEAGKISGKMELEKNSGTGNKYRTKKDHMMCKLMCLCIAYSSTIGGLTTITGTSTNLIFAEHFNMRYPDCHCINFGSWFIMSFPAAIIILLLSWIWLQWLFLGFNFKEMFQCDKTGTAKQKACAEVIKQEYQKLGPIRYQEIVTLVLFIVMAVLWFSRDPGFVPGWSALFSQYPGFATDSTVALLVGLLFFLIPAKRLTKTTPTGETVAFDYSPLITWKEFQSFMPWDIAILVGGGFALADGCEESGLSKWIGNKLSPLGSLPVWLIILISSLFVTSLTEVASNPATITLLLPILAPLAEAIHVNPLYILLPSTLCTSFAFLLPVANPPNAIVFSYGHLTVIDMVKAGLGVNVLGVAVVMLGLFVWMVPMFDLHTYPSWAPTIANETLP", "length": 594 }, "evidence": [ { "id": "A0A8C2LMT7", "url": "https://omabrowser.org/oma/group/A0A8C2LMT7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q07782-1", "protein_name": "Solute carrier family 13 member 1", "gene_name": "Slc13a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLLNYAFVYRRFLLVVFTVLVLLPLPLIIRSKEAECAYILFVIATFWITEALPLSITALLPGLMFPMFGIMSSTHVASAYFKDFHLLLIGVICLATSIEKWNLHKRIALRMVMMVGVNPAWLTLGFMSSTAFLSMWLSNTSTAAMVMPIVEAVAQQITSAEAEAEATQMTYFNESAAQGLEVDETIIGQETNERKEKTKPALGSSNDKGKVSSKMETEKNTVTGAKYRSKKDHMMCKLMCLCIAYSSTIGGLTTITGTSTNLIFSEHFNTRYPDCRCLNFGSWFLFSFPVAVILLLLSWIWLQWLFLGFNFKEMFKCGKTKTLKEKACAEVIKQEYEKLGPMRYQEIVTLVIFIVMALLWFSRDPGFVTGWSVLFSEYPGYVTDSTVALVAGILFFLIPAKKLTKMTSTGDIIAFDYSPLITWKEFQSFMPWDIAILVGGGFALADGCQVSGLSSWIGSKLSPLGSLPVWLIILISSLIVTSLTEVASNPATITILFPILSPLAEAIHVNPLHILLPSTLCTSFAFLLPVANPPNAIVFSYGHLKVIDMVKAGLGVNILGVAVVMLGMFTWIEPMFNLHEYPSWAPDIVNQTMP", "length": 595 }, "evidence": [ { "id": "A0A8C2LMT7", "url": "https://omabrowser.org/oma/group/A0A8C2LMT7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BZW2-1", "protein_name": "Solute carrier family 13 member 1", "gene_name": "SLC13A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKFFSYILVYRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTALLPSLMLPMFGIMPSKKVASAYFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNPAWLTLGFMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIINAEAEVEATQMTYFNGSTNHGLEIDESVNGHEINERKEKTKPVPGYNNDTGKISSKVELEKNSGMRTKYRTKKGHVTRKLTCLCIAYSSTIGGLTTITGTSTNLIFAEYFNTRYPDCRCLNFGSWFTFSFPAALIILLLSWIWLQWLFLGFNFKEMFKCGKTKTVQQKACAEVIKQEYQKLGPIRYQEIVTLVLFIIMALLWFSRDPGFVPGWSALFSEYPGFATDSTVALLIGLLFFLIPAKTLTKTTPTGEIVAFDYSPLITWKEFQSFMPWDIAILVGGGFALADGCEESGLSKWIGNKLSPLGSLPAWLIILISSLMVTSLTEVASNPATITLFLPILSPLAEAIHVNPLYILIPSTLCTSFAFLLPVANPPNAIVFSYGHLKVIDMVKAGLGVNIVGVAVVMLGICTWIVPMFDLYTYPSWAPAMSNETMP", "length": 595 }, "evidence": [ { "id": "A0A8C2LMT7", "url": "https://omabrowser.org/oma/group/A0A8C2LMT7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JHI4-1", "protein_name": "Solute carrier family 13 member 1", "gene_name": "Slc13a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLLNYALVYRRFLLVVFTILVFLPLPLIIRTKEAQCAYILFVIAIFWITEALPLSITALLPGLMFPMFGIMRSSQVASAYFKDFHLLLIGVICLATSIEKWNLHKRIALRMVMMVGVNPAWLTLGFMSSTAFLSMWLSNTSTAAMVMPIVEAVAQQIISAEAEAEATQMTYFNESAAHGLDIDETVIGQETNEKKEKTKPAPGSSHDKGKVSRKMETEKNAVTGAKYRSRKDHMMCKLMCLSVAYSSTIGGLTTITGTSTNLIFSEHFNTRYPDCRCLNFGSWFLFSFPVALILLLLSWIWLQWLYLGFDFKMFKCGKTKTLKEKACAKVIKQEYEKLGPMRYQEIVTLVIFIVMALLWFSRDPGFVTGWSVLFSEYPGYVTDSTVALVAGILFFLIPAKKVTKMTSAGEIIAFDYTPLITWKEFQSFMPWDIAILVGGGFALADGCQVSGLSNWIGSKLSPLGSLPVWLIILISSLIVTSLTEVASNPATITILFPILSPLAEAIQVNPLQILLPSTLCTSFAFLLPVANPPNAIVFSYGHLKVIDMVKAGLGVNILGVAVVMLGMFTWIEPMFNLHEYPSWASNFVNQTMP", "length": 594 }, "evidence": [ { "id": "A0A8C2LMT7", "url": "https://omabrowser.org/oma/group/A0A8C2LMT7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VDQ0-1", "protein_name": "Protein I'm not dead yet 2", "gene_name": "Indy2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": 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"UniProtKB", "id": "A0A8C2LMT7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMT7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LMT7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMT7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 591, "end_pos": 593, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], 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"https://www.ncbi.nlm.nih.gov/protein/XP_035298716" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035298716", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298716" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LMY4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMY4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC118238601", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMY4", "locus": {} } ], "crossref": [ { "id": "IPR044822", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044822", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:118238601", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:118238601", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SEPPTRW", "url": "https://omabrowser.org/oma/group/SEPPTRW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LMY4", "url": "https://www.orthodb.org/?gene=A0A8C2LMY4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47595", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47595", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47595:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47595:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13837", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13837", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035298716", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298716", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LMY4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LMY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMY4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATTNSSAGIRWSRQETRTLLSILGEAEYIQRLQTMHHNADVYQAVSKRMQQEGFRRTERQCRSKFKVLKALYLKAYVAHATSMGDPPHCPFYDTLDQLLRNQIVTDPDNLTEAAAWAKHCDQNLVASNTPGEEGTNMRKVKRIQAAGHQHVLQTVKESDEDCQLRISDRIREASDLEDSWDDSSVAGCSQGTPSYSSSHHLFRGAVAPCQSSPMTRLGMSGESSPCTNTNRNPLGAASTSQPPGSSSRVAFLSGGDRLLTSEPPPRWARRRRRSVARTIAAELAENRRLARELSKKEEEKLDRLIAIGEEASAQQDTANELRRDAVIAVRRLATAVEEATGAFQLGLEKLLQRLISNTKS", "length": 361, "header": "tr|A0A8C2LMY4-1|A0A8C2LMY4_CRIGR Isoform 1 of Zinc finger and SCAN domain containing 29 OS=Cricetulus griseus OX=10029 GN=LOC118238601 PE=4 SV=1 CANONICAL=A0A8C2LMY4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LMY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMY4/entry#A0A8C2LMY4-1", "sequence": { "sequence": "MATTNSSAGIRWSRQETRTLLSILGEAEYIQRLQTMHHNADVYQAVSKRMQQEGFRRTERQCRSKFKVLKALYLKAYVAHATSMGDPPHCPFYDTLDQLLRNQIVTDPDNLTEAAAWAKHCDQNLVASNTPGEEGTNMRKVKRIQAAGHQHVLQTVKESDEDCQLRISDRIREASDLEDSWDDSSVAGCSQGTPSYSSSHHLFRGAVAPCQSSPMTRLGMSGESSPCTNTNRNPLGAASTSQPPGSSSRVAFLSGGDRLLTSEPPPRWARRRRRSVARTIAAELAENRRLARELSKKEEEKLDRLIAIGEEASAQQDTANELRRDAVIAVRRLATAVEEATGAFQLGLEKLLQRLISNTKS", "length": 361, "header": "tr|A0A8C2LMY4-1|A0A8C2LMY4_CRIGR Isoform 1 of Zinc finger and SCAN domain containing 29 OS=Cricetulus griseus OX=10029 GN=LOC118238601 PE=4 SV=1 CANONICAL=A0A8C2LMY4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 193, "start_aa": "Thr", "end_pos": 193, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr193", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LMY4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMY4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LMY4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LMY4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:118238601", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:118238601", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1W2PQ72-1", "protein_name": "Myb/SANT-like DNA-binding domain-containing protein 7", "gene_name": "MSANTD7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASANSSAGIRWSRQETRTLLSILGEAEYIQRLQTVHHNADVYQAVSKRMQQEGFRRTERQCRSKFKVLKALYLKAYVAHATSMGEPPHCPFYDTLDQLLRNQIVTDPDNLMEDAAWAKHCDQNLVASDAPGEEGTGILKSKRTQAADHQPILKTVKASDEDCQLRISDRIRETSDLEDSWDESSGAGCSQGTPSYSSSHSLFRGAVAPCQSSPMARLGVSGEPSPCTSTNRSTPGVASTPQTPVSSSRAGFVSGGDRPLTSEPPPRWARRRRRSVARTIAAELAENRRLARELSKREEEKLDRLIAIGEEASAQQDTANELRRDAVIAVRRLATAVEEATGAFQLGLEKLLQRLISNTKS", "length": 361 }, "evidence": [ { "id": "A0A8C2LMY4", "url": "https://omabrowser.org/oma/group/A0A8C2LMY4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A287AF59-1", "protein_name": "Myb/SANT DNA binding domain containing 7", "gene_name": "MSANTD7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATSNSSAGIRWSRQETRTLLSILGEAEYIQRLQTVHHNADVYQAVSKRMQQEGFRRTERQCRSKFKVLKALYLKAYVAQATSMGDPPHCPFYDTLDQLLRNQVVTDPDNLMEDAAWAKHCDQNLTASDTPGEERTSILGPKRTQAADHQPLLKTVKESDGNCQLRISDQVQESSDLEDSWDESSGAGCSQGTPSYSSSHHLFRGAVAPCQSSPMTRQGVSGEPSPCTSTGRNTPGVASAQQPPGSSSRVPFVSGGDRPLTSEPPPRWARRRRRSVARTIAAELAENRRLARELSKREEEKLDRLIAIGEEASAQQDTANELRRDAVLAVRRLATAVEEATGAFQLGLEKLLQRLISNTKS", "length": 361 }, "evidence": [ { "id": "A0A8C2LMY4", "url": "https://omabrowser.org/oma/group/A0A8C2LMY4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZUB3-1", "protein_name": "Myb/SANT DNA binding domain containing 7", "gene_name": "Msantd7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616451.1) annotated using gene prediction method: Gnomon. 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027255339", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255339" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LNB4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNB4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100764627", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNB4", "locus": {} } ], "crossref": [ { "id": "100764627", "url": "https://www.ncbi.nlm.nih.gov/gene/100764627", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032017", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032017", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764627", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764627", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LNB4", "url": "https://www.orthodb.org/?gene=A0A8C2LNB4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46176", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46176", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46176:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46176:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027255339", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027255339", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LN23", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LN23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LN23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LN23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LNB4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LNB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNB4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNKCQRCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRASHQEKEQYSRLSSGSHYNSQKTLSTSSIQNEIPKKKSKFESITTNGDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQTRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEKSGTITSP", "length": 307, "header": "tr|A0A8C2LNB4-1|A0A8C2LNB4_CRIGR Isoform 1 of Protein FAM76A isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC100764627 PE=3 SV=1 CANONICAL=A0A8C2LNB4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LN23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNB4/entry#A0A8C2LN23-1", "sequence": { "sequence": "MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNKCQRCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRASHQEKEQYSRLSSGSHYNSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQTRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEKSGTITSP", "length": 278, "header": "tr|A0A8C2LN23-1|A0A8C2LNB4_CRIGR Computationally mapped isoform of Protein FAM76A isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC100764627 PE=3 SV=1 CANONICAL=A0A8C2LNB4-1" }, "locus": {} }, { "isoform_ac": "A0A8C2LNB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNB4/entry#A0A8C2LNB4-1", "sequence": { "sequence": "MAALYACTKCHQRFPFEALSQGQQLCKECRIAHPVVKCTYCRTEYQQESKTNTICKKCAQNVQLYGTPKPCQYCNIIAAFIGNKCQRCTNSEKKYGPPYSCEQCKQQCAFDRKDDRKKVDGKLLCWLCTLSYKRVLQKTKEQRKHLSSSSRASHQEKEQYSRLSSGSHYNSQKTLSTSSIQNEIPKKKSKFESITTNGDSFSPDLALDSPGTDHFVIIAQLKEEVATLKKMLHQKDQMILEKEKKITELKADFQYQESQTRAKMNQMEKTHKEVTEQLQAKNRELLKQAAALSKSKKSEKSGTITSP", "length": 307, "header": "tr|A0A8C2LNB4-1|A0A8C2LNB4_CRIGR Isoform 1 of Protein FAM76A isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC100764627 PE=3 SV=1 CANONICAL=A0A8C2LNB4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613677.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003498073", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498073" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LNB2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNB2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Terb2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNB2", "locus": {} } ], "crossref": [ { "id": "100751713", "url": "https://www.ncbi.nlm.nih.gov/gene/100751713", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028065", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028065", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751713", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751713", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WFCRSVS", "url": "https://omabrowser.org/oma/group/WFCRSVS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LNB2", "url": "https://www.orthodb.org/?gene=A0A8C2LNB2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35345", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35345", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35345:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35345:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15101", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15101", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003498073", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498073", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LNB2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LNB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNB2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFQGQRGWFCRSVSQDLRQFWVDEGGTVSDVQAADFLFSCDASHPDTLRIYQSLEYIEDNATVFHAYYLSAVANTEMKNSVALGHFVLPPACLQKEIRRKIGSFIWEQDENFLVKKHDRITSNERESSEPTTEHKKELYESAENHFVRTPVVEKQMYFPLQNYPVNNMVTGYISIDALEKFLGELHDFIPGSSGYLAYHVQNEINMSAIKNKLRRKLS", "length": 218, "header": "tr|A0A8C2LNB2-1|A0A8C2LNB2_CRIGR Isoform 1 of Telomere repeats-binding bouquet formation protein 2 OS=Cricetulus griseus OX=10029 GN=Terb2 PE=4 SV=1 CANONICAL=A0A8C2LNB2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LNB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNB2/entry#A0A8C2LNB2-1", "sequence": { "sequence": "MFQGQRGWFCRSVSQDLRQFWVDEGGTVSDVQAADFLFSCDASHPDTLRIYQSLEYIEDNATVFHAYYLSAVANTEMKNSVALGHFVLPPACLQKEIRRKIGSFIWEQDENFLVKKHDRITSNERESSEPTTEHKKELYESAENHFVRTPVVEKQMYFPLQNYPVNNMVTGYISIDALEKFLGELHDFIPGSSGYLAYHVQNEINMSAIKNKLRRKLS", "length": 218, "header": "tr|A0A8C2LNB2-1|A0A8C2LNB2_CRIGR Isoform 1 of Telomere repeats-binding bouquet formation protein 2 OS=Cricetulus griseus OX=10029 GN=Terb2 PE=4 SV=1 CANONICAL=A0A8C2LNB2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LNB2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNB2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LNB2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNB2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751713", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751713", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A1L6-1", "protein_name": "Telomere repeat binding bouquet formation protein 2", "gene_name": "Terb2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFQGQRGWFCRSVSQALRQFWVDQGGMVSDAQAADFLFSCDASHPDTLRIYQSLEYTEDSATVFHAYYLAAVANAEKKNSVALGHFVLPPACLQKEIRRKIGSFIWEQDEKFQIEKHSRATSSVKGSTGPTTEHKQELSKSTENHLIRTPAIEKQTCFPLQNYPVNNMVTGYVSIDTLEKFLGELRDFIPGNSGYLAYHVQNEINMSVIKNKLRRKLS", "length": 218 }, "evidence": [ { "id": "A0A8C2LNB2", "url": "https://omabrowser.org/oma/group/A0A8C2LNB2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SN26-1", "protein_name": "Telomere repeat binding bouquet formation protein 2", "gene_name": "TERB2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFQGQRGWFCGSVSGDLRQFWVAEGGTISDLRAADYLFSCDASHPDTLRIYQSLDYIEDNATVFHAYYLSAVANAEIKNSVALGHFILPPACLQKEIRRKIGNFIWEQDQRFLLEKHDEVTPNEIKAFRESSELATDHKKELSTSTEKHFIRTPVVEKQMYFPLQNYPVNNMVTGYISIDAMKKFLGELHDFIPGSSGYLAYHVQNEINMSAIKNKLKRKY", "length": 221 }, "evidence": [ { "id": "A0A8C2LNB2", "url": "https://omabrowser.org/oma/group/A0A8C2LNB2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q2M2T9-1", "protein_name": "Telomere repeats-binding bouquet formation protein 2", "gene_name": "TERB2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFQGQRGWFCGSVSHDLRQFWVAEGGTISDPRAADFLFSCDASHPDTLRIYQSLDYIEDNATVFHAYYLSAVANAEIKNSVALGHFILPPASLQKEIRRKIGSFIWEQDQHFLIEKHDEVTSNELKVFRESSVLATDHKKDLSKSTEKHFIRTPVVEKQMYFPLQHYPVNNMVTGYISIDAMKKFLGELHDFIPGSSGYLAYHVQNEINMSAIKNKLKNKY", "length": 221 }, "evidence": [ { "id": "A0A8C2LNB2", "url": "https://omabrowser.org/oma/group/A0A8C2LNB2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8NHR7-1", "protein_name": "Telomere repeats-binding bouquet formation protein 2", "gene_name": "TERB2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFQGQRGWFCGSVSQDLRQFWVAEGGTISDPRAADFLFSCDASHPDTLRIYQSLDYIEDNATVFHAYYLSAVANAKIKNSVALGHFILPPACLQKEIRRKIGSFIWEQDQHFLIEKHDEVTPNEIKTLRENSELATEHKKELSKSPEKHFIRTPVVEKQMYFPLQNYPVNNMVTGYISIDAMKKFLGELHDFIPGTSGYLAYHVQNEINMSAIKNKLKRK", "length": 220 }, "evidence": [ { "id": "A0A8C2LNB2", "url": "https://omabrowser.org/oma/group/A0A8C2LNB2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D494-1", "protein_name": "Telomere repeats-binding bouquet formation protein 2", "gene_name": "Terb2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQGQRGWFCGSVSQDLRQIWEDEGGMVSDVKAADFLFSCDASHPDTLRIYQSLEYIEDNATVFHAYYLAAIANTEMKNSVALGHFVLPPACLQKEIRRKIGSFIWEQDEKFQIEKHDRMASSDKENIRPTPEHKQELSKSAEHHLTRTPVIEKQMCFPLHSYPVNNMVTGYISIDALEKFLGELHDFTPGSSGYLAYHIQDEINMSAIKNKLRRKLS", "length": 218 }, "evidence": [ { "id": "A0A8C2LNB2", "url": "https://omabrowser.org/oma/group/A0A8C2LNB2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "meiotic attachment of telomere to nuclear envelope", "id": "GO:0070197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070197", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LNB2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNB2" } ], "pmid": "" }, { "name": "homologous chromosome pairing at meiosis", "id": "GO:0007129", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007129", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LNB2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNB2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear inner membrane", "id": "GO:0005637", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005637", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LNB2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNB2" } ], "pmid": "" }, { "name": "chromosome, telomeric region", "id": "GO:0000781", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000781", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LNB2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNB2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 60, "end_pos": 62, "annotation": 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:: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614050.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003504339", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504339" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LNB3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNB3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tsnaxip1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNB3", "locus": {} } ], "crossref": [ { "id": "100754120", "url": "https://www.ncbi.nlm.nih.gov/gene/100754120", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032755", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032755", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754120", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754120", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EWGYNLH", "url": "https://omabrowser.org/oma/group/EWGYNLH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LNB3", "url": "https://www.orthodb.org/?gene=A0A8C2LNB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16306", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16306", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16306:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16306:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15739", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15739", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003504339", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003504339", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LNB3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LNB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNB3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MANPQTRYYSFSKSRTGTQSSGGTAEVKGVEKRKLSQKRRTLPFQLSMGGHLSPWPTYTSGQTILYQRKPCSEDCRNRTNSWQQHPLGTSKPRYLEQLENYLRKELLLLDLGTDSAQELRLQPYREIFEFFIEDFKTYKPLLSSIKNAYEVMLAHQREKIRALEPLKAKIITMNEDCSERILAMRAEERYEISLLKKEKMNLLKLIDKKNEEKISLQSEVSKLRKSLAEEYLRYLTERDARKILIGDLNELRYQREDMSLAQSPGVWGEDPVKLTLALKMTRQDLTRIQMELNTMKANFGDVVPRRDFEKQEKINLDLQEQLESLKADYEEVRKEHELLLQLHMTTLKERDQFYAELQEIQRTSTPRPDWTKCEGIIAGGSERWLMLAEGKNSDQLVDVLLEEIGSGLLREKDFFPGLGLEESVPAFLRFDGPVENKKPSKKEVVNILEDAWKERLAQEQKESFQDFFTNFLERRFGSNDAIAWAYTIFENIKLFRSIEVMNQFYAVLMGKRKETVYINQRETMSHLMKEMTNIDTQNEGLITMEQFSTILKTTFPLKKEEQIQELIEAAGWSPDINNVEMFNYRTLFTEDEEGQSEPFVQKLWEQYDSEKEAYLQELKEDLGQELTDEVSLSKMRVALMNIDPSLDKQTLCTYLSQAFQLPVAELPLEDEEKQEEIVVKLETALEQLRIADTKRVGLREPEPAS", "length": 705, "header": "tr|A0A8C2LNB3-1|A0A8C2LNB3_CRIGR Isoform 1 of Translin-associated factor X-interacting protein 1 OS=Cricetulus griseus OX=10029 GN=Tsnaxip1 PE=4 SV=1 CANONICAL=A0A8C2LNB3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LNB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNB3/entry#A0A8C2LNB3-1", "sequence": { "sequence": "MANPQTRYYSFSKSRTGTQSSGGTAEVKGVEKRKLSQKRRTLPFQLSMGGHLSPWPTYTSGQTILYQRKPCSEDCRNRTNSWQQHPLGTSKPRYLEQLENYLRKELLLLDLGTDSAQELRLQPYREIFEFFIEDFKTYKPLLSSIKNAYEVMLAHQREKIRALEPLKAKIITMNEDCSERILAMRAEERYEISLLKKEKMNLLKLIDKKNEEKISLQSEVSKLRKSLAEEYLRYLTERDARKILIGDLNELRYQREDMSLAQSPGVWGEDPVKLTLALKMTRQDLTRIQMELNTMKANFGDVVPRRDFEKQEKINLDLQEQLESLKADYEEVRKEHELLLQLHMTTLKERDQFYAELQEIQRTSTPRPDWTKCEGIIAGGSERWLMLAEGKNSDQLVDVLLEEIGSGLLREKDFFPGLGLEESVPAFLRFDGPVENKKPSKKEVVNILEDAWKERLAQEQKESFQDFFTNFLERRFGSNDAIAWAYTIFENIKLFRSIEVMNQFYAVLMGKRKETVYINQRETMSHLMKEMTNIDTQNEGLITMEQFSTILKTTFPLKKEEQIQELIEAAGWSPDINNVEMFNYRTLFTEDEEGQSEPFVQKLWEQYDSEKEAYLQELKEDLGQELTDEVSLSKMRVALMNIDPSLDKQTLCTYLSQAFQLPVAELPLEDEEKQEEIVVKLETALEQLRIADTKRVGLREPEPAS", "length": 705, "header": "tr|A0A8C2LNB3-1|A0A8C2LNB3_CRIGR Isoform 1 of Translin-associated factor X-interacting protein 1 OS=Cricetulus griseus OX=10029 GN=Tsnaxip1 PE=4 SV=1 CANONICAL=A0A8C2LNB3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LNB3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNB3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LNB3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNB3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754120", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754120", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZFD5-1", "protein_name": "Translin associated factor X interacting protein 1", "gene_name": "TSNAXIP1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAARRAVRGGTSPESSSEITSGQTHIRSAKPTLPKKQKALSLQLSARGQWSMWPAFAAGQTVLRNHKPCSAPEERTCSNEQALLTIPKPRHLEQLESYLRKELQTLDLTKGISQELKLQPYREIFEFFIDNFKTYKPLLSAIKNEYEATLAHQKEMIRALEPLKAMVTTVSEECTQQILALQEKEKVEINTLKQEKHHLLKFIDNMKEEKCSLQTQVEHLQMSVAEEYTRYLQEYGARKLLLAKLNDMHNEQLNVKQHQAQEKAVKGEDVVKLTLALKMARQDLTKAQVKLNAMTAEYGDVVPRRRFESLEKKYSDLLQEMKTLRKDFDQLHEEYGTLLEIHRETAEERDSFFTRLQEAERSHTPRPNWAKCSEVIPGGAERWDCLAKGKSSHQLVDVLLEEIGTGVLKEMNVFRGWGKGNKVPVHLRYEGEVKNKKPTKKDVVNILKDIWKEKTALDQQTGKRSSLPEFFLSYLQKKYGDASAVEWSYTLSEYMRLCPSNHVMSSFYEILTGKVAEEQYHSQNQLISDLQKELAACDSYSSGSLPSEQFRMALREAFPLKRRDAIQELVDASMFSLDSDDDFIDYISLFKEDEEGNPEPFVAKLRSQYVSEKQEYLQELKNSLGDVTEVDADDLKAAFCRIDPEISDQTLDAYIGLAYQVRREQPDQEVVPVDTILERLCVGDVRRVGPSPRKESTTDFEGE", "length": 703 }, "evidence": [ { "id": "A0A8C2LNB3", "url": "https://omabrowser.org/oma/group/A0A8C2LNB3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A5WVR3-1", "protein_name": "Translin-associated factor X-interacting protein 1", "gene_name": "tsnaxip1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAVKDLQLPPLLHSRSSSQFESNDDNNRGLQRHIANKMSRAKLIKQTKEKEKSYFSSEPAEVTFQKPRQIRNYGSLAKPRFLEQLECLLKRELEVLDNTQDSKVQELRLQVYQEVFGHLIEEFKTYKPILSAIKKEYDITLAHLRDQIRDLLPLRPKLVLVSEQCDKKILEMRVQEREEVRALKQECRHLQSVIESMRSQQSALQIQVDHLKEDLATQYQLYRDERDARKLLITRISTMQSTQDAEHDDNNEEDESEDPVVVKMALQVCREDLTKAQIELNRLQAEYSDVVPRRDWDNLNHLHEETLMKLETLQTDFNQVKSEYDTLLEVHQKSAPTTQQHGSDSQHIATTPRPNWEQCSDILGGTERCKELFEGQSSQKRLEILMKEINSQNQFFTGLGTSSDVPIYLRYEGKLKNLKLKKADVIKVIKEIWRNKMADNEKNDDPRDLQTFLHSYLVEQYKDKAGEWAYSLMESVQNNLKDDLICLFNDVLTGKVDESIYHGQTQLLSHLLKVLIQSDITQCGSLTVSEFSEALRKAFPLKSDQDIEELLAAAQTELESSGVRISYQTLYTEDTDGQHKEFLSLVKKQATAERLQYISELRAQLEGKGEVDAEQLWVAFKTIDPSLEPENLEWNLSVAFQTKESELQAQALEKEVVLQRLSVAHVKRAGPKG", "length": 673 }, "evidence": [ { "id": "A0A8C2LNB3", "url": "https://omabrowser.org/oma/group/A0A8C2LNB3/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZU07-1", "protein_name": "Translin-associated factor X interacting protein 1", "gene_name": "Tsnaxip1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANPQTRNQSFSKLRTRTQSSGGTPEAESIEKRKLSQKRRTLPLQLSMCGHLSPWPTYTSGQTILHKRKPCSDDSRNRANSWQQQPLSISKPRYLEQLENYLRKELLLLDLSTDSAQELRLQPYREIFEFFIEDFKTYKPLLSSIKNAYEVMLAHQREKIRSLEPLKAKIVTVNEDCSERVLAMRAEERHEISVLKKEKMNLLKLIDKKNEEKISLQCEVAKLRKSLAEEYLRYLTERDARKILIGDLNELRYQREDMSLAQSPGVWGEDPVKLTLALKMTRQDLTRTQMELNTMKANFGDVVPRRDFEMQEKTNMELQEQLESLRGDYEEVRKEHEMLLQLHMSTLKERDQFYNELQEIQRTSTPRPDWTKCESVIAGGQERWLVLAEGKNSDQLVDVLLEEIGMGLLREKDFFPGLGFGDSIPPFLRFDGPVKNKKPSKKEVVNLLKDAWKERVAEEQKESFPDFFFNFLERRFGVNEAMAWAYTIFENIKLFRSSEIMSQFYAVLMGKTLESVYINQKDTLFHLLKELINADTQNEGSITMEQFSTVLKTTFPLKKEEQIMELMEAAGWGPDSSNTDMLNYRSLFTEDEEGQSEPFVQKLWEQYNSEKEAYLEELKQELNMEPLEEVTLLKMRGTLMNIDPTMDRQTLSAYLSQAYQIPAIDVPLDDEERQGIISVTLETALDRLKMADTKRVGPREPEQAS", "length": 705 }, "evidence": [ { "id": "A0A8C2LNB3", "url": "https://omabrowser.org/oma/group/A0A8C2LNB3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S2K6-1", "protein_name": "Translin associated factor X interacting protein 1", "gene_name": "TSNAXIP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASSKPQCPSLATTSRIHLRPLGVTKDDSFITETKNPQKRKLSQKRKTLLSCPFSIGGHLSPWPRYISDQTILHNRKPCSDDYQKRTNSWQQPLGTTKPRYLEQLENYLRKELLLLDLGTDSAQELRLQPFREIFEFFIEDFKTYKPLLSSIKNAYEVMLAHQREKIRALEPLKAKLVIVDEDCKERILAMRAEERYEISMLKKEKMNLLKLIDKKNEEKISLQSEVSKLRKNLAEEYLHYLSERDARKILIADLNELRYQREDMSLAQSPGIWGEDPMKLTLALKMARQDLTRTQMELNTMKANFGDVVPRRDFEMQEKVLKDLQEQLDSLRDDYEEVRKEHEMLLQLHMSTLKERDQFYSELQEIQRTSTPRPDWSKCKDVVAGGRDRWQMLAEGKNSDQLVDVLLEEIGEGLLREKDFFSGLGYGESIPTFLRFDGTVENKKPTKKDVVNILKDAWKERMAEEQKERFPDFFFNFLERRFGPGDAMAWAYTIFEYIKLFQSNEVMSQFHAVLMGKRKESVYIKQKERIAQLLKEMTNADSQNEGLLTVEQLSTVLKSAFPFKTDEKIQELMEAVGWHPSSSNADLLNYHILFTEDEEGQSTPFVQKLWEQYMEEKDAYLQELKLELGLELHEDVTLARMREALMNIDPTLDKQTLNSYLSQAFQFPMTELPEEGEEKEAGIVVQLQTALEQLHMSDVRRMGPREQEPAS", "length": 712 }, "evidence": [ { "id": "A0A8C2LNB3", "url": "https://omabrowser.org/oma/group/A0A8C2LNB3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q2TAA8-1", "protein_name": "Translin-associated factor X-interacting protein 1", "gene_name": "TSNAXIP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGGHLSPWPTYTSGQTILQNRKPCSDDYRKRVGSCQQHPFRTAKPQYLEELENYLRKELLLLDLGTDSTQELRLQPYREIFEFFIEDFKTYKPLLSSIKNAYEGMLAHQREKIRALEPLKAKLVTVNEDCNERILAMRAEEKYEISLLKKEKMNLLKLIDKKNEEKISLQSEVTKLRKNLAEEYLHYLSERDACKILIADLNELRYQREDMSLAQSPGIWGEDPVKLTLALKMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQEKTNKDLQEQLDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSELQEIQRTSTPRPDWTKCKDVVAGGPERWQMLAEGKNSDQLVDVLLEEIGSGLLREKDFFPGLGYGEAIPAFLRFDGLVENKKPSKKDVVNLLKDAWKERLAEEQKETFPDFFFNFLEHRFGPSDAMAWAYTIFENIKIFHSNEVMSQFYAVLMGKRSENVYVTQKETVAQLLKEMTNADSQNEGLLTMEQFNTVLKSTFPLKTEEQIQELMEAGGWHPSSSNADLLNYRSLFMEDEEGQSEPFVQKLWEQYMDEKDEYLQQLKQELGIELHEEVTLPKLRGGLMTIDPSLDKQTVNTYMSQAFQLPESEMPEEGDEKEEAVVEILQTALERLQVIDIRRVGPREPEPAS", "length": 658 }, "evidence": [ { "id": "A0A8C2LNB3", "url": "https://omabrowser.org/oma/group/A0A8C2LNB3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99P25-1", "protein_name": "Translin-associated factor X-interacting protein 1", "gene_name": "Tsnaxip1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANLQERKSFSKPRISIQASGGTPEAKGIEKRKLSQKRRTLPLQLSLGGHLSPWPTYTSGQTVLHNRKPCSDDSRNRANSCQQQSMSISKPKYLEQLENYLRKELLLLDLSTDSAQELRLQPYREIFEFFIEDFKTYKPLLSSIKNAYEVMLAHQKERIRSLEPLKAKIVTMNEDCSERVLAMRAEERYEISVLKKEKMNLLKLIDKKNEEKISLQSEVAKLRRSLAEEYLRYLTERDARKILIGDLNELRYQQEDMSLAQTPGVWGEDPVKLTLALKMTRQDLTRTQMELNTMKANSGDVVPRRDLEMQEKTNMELQEQLESLKADYEEVQKEHELLLQLHMSTLKERDQFYNELQEIQRTSTPRPDWTKCESIIAGGPERWLVLAEGKNSDQLVDVLLEEIGMGLLREKDFFPGLGFGDAIPPFLRFDGPVKNKKPSKKEVVNLLKDAWKERIAEEQKEPFPDFFFNFLERRFGVNDAMAWAYTIFENIKLFRSSEIMNQFYAVLMGKNLESVYINQKKTLSHLLKELLSVDTQNEGSITMEQFSTILKTTFPLKKEEQIQELMEAVGWGPDSSNTDMLNYRSLFNEDEEGQSEPFVQRLWEQYESDKEAYLEELKQELDLDPLEDVTLLKMRGTLMNIDPTMDKQTLSAYLSQAYQIPAIDVPLEDEEKQGIISIKVETALDRLRMADTKRVGPREPDPAS", "length": 704 }, "evidence": [ { "id": "A0A8C2LNB3", "url": "https://omabrowser.org/oma/group/A0A8C2LNB3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LNB3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNB3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LNB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNB3" }, { "id": "PF15739", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15739" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Translin-associated factor X-interacting protein 1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 99, "end_pos": 208, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 77, "end_pos": 79 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LNB5-1", "uniprot_ac": "A0A8C2LNB5", "uniprot_id": "A0A8C2LNB5_CRIGR", "mass": { "chemical_mass": 23659.0, "monoisotopic_mass": 23659.0 }, "refseq": { "ac": "XP_003495100", "name": "lysM and putative peptidoglycan-binding domain-containing protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495100" }, "gene_names": [ { "name": "Lysmd2", "type": "recommended", 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LUE5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LUE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUE5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FQY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FQY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FQY7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FTH3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FTH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FTH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GUC9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GUC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GUC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GUC9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GYC0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GYC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYC0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JF52", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JF52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JF52-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JF52-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASKARRLPREEGPPTAAGLLREACYLCGEDCTRDARAVPSRIVNGNSGGSMHFPFLSLLPCPPNARPPNKHCEVRSCPKCFSVLEDVWALYRASHNRELINSVQGFLGRYHQAFSASDPTLSDLPASAQGGPPAVCYICGAELGPGKEFQLSMNPASHLGEKEPFFPFLTVYPPAPRARPADSTGLVATCVLCYHDLLGQWLQHEARAAHQAVSAWSRQYQVDTFVCFFCQQEKKRCLGLKSVRVARLPLFLYTLRASHSLLVDDGRQLIIGACVECGTLVCAGQGLVSQGSMGWSSPAAGATKVTSAPQETPTIVHAPAPEPELQPVPPTDSLSRATRTTQELRPVSSQQSSRDSWDGDGVDLTATGMSHEPKSPSVGMLSTATRTTATVNPLTPSPLNGALVPTGSPATSSTLSAQAAPSSSFAAALRKLAKQAEEPRGSSLSSESSPVSSPATNHSSPASTPKRVPMGPIIVPPGGHSVPSTPPVVTIAPTKTVNGVWRSESRQDSVSRGSSSGRERLLVEPPLAQEKAAGPTIPSHLLSTPYPFGLSPSSVVQDSRFQPLNLQRPVHHVVPPSTVTEDYLRSFRPYHTAEDLRMSSLPPLGLDPATAAAYYHPSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIPTPGSLPPLHPSAMHLHLSGVRYPPELSHSSLAALHSERMSSLSAERLQMDEELRREREREREREREADREREKEREREQREKEREKELEREREKERERELERQREQRAREKDLLAAKALEPTFLPVAELHGLRSHATEERPKPSEQLTPTRAEKLKDVGLQAPKPMQHPLHPVPAPHHTVPSLISSHGIFSLPGNSAATALLIQRTNEEEKWLARQRRLRQEKEDRQSQVSEFRQQVLEQHLDLGRPPVPTEVEHRPESTRPGSNRHDQSSREPPQHFGGPPPLISPKPQHHTVPTALWNPVSLMDNALETRRAESHSLHSHPTAFEPSRPAAVPLVKVERVYCTEKAEEPRKREATPLDKYQPPPRETGSLEPQTFPHGPGPFLAELEKSTQTILSQQRPSLSQATSFGELSGPLKPGSPFCQPTPRGPDPAYIYDEFLQQRRRLVSKLDLEERRRREAQEKGYYYDLDDSYDESDEEEVRAHLRCVAEQPPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRERSPSPPAIQSKRQTPSPRLALSTRYSPDEMNNSPNFEEKRKFLTFFNLTHISAEKRKDRERLVEMLRAMKQRALSAAVADSVTNSSRDSPSISLSEPATQPAPLETDQPAGVPASLSDVPKAVETGRLEQLRPQELLRVQEPAPTSGEKARLSEAPGGKKNLSMLHYLRGAAPKDIPVPLSHSINGKSKPWEPFMAEEFAHQFHESVLQSTQKALQKHKGSSAVLSAEQNHKVDTSVHYNIPELQSSSRVPLPQHNGQQEPPAGRKGPPMQEVDQDSEEDNEDDSEEEAEEAPRRQWQGIEAIFEAYQEHIEEQNLERQVLQTQCRRLEAQNYSLSLTAEQLSHSMAELRSQKQKMVSERERLQAELDHLRKCLALPTMHWPRGYFKGYPR", "length": 1575, "header": "tr|A0A8C2LNG0-1|A0A8C2LNG0_CRIGR Isoform 1 of Genetic suppressor element 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Gse1 PE=4 SV=1 CANONICAL=A0A8C2LNG0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LNG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNG0/entry#A0A8C2LNG0-1", "sequence": { "sequence": "MASKARRLPREEGPPTAAGLLREACYLCGEDCTRDARAVPSRIVNGNSGGSMHFPFLSLLPCPPNARPPNKHCEVRSCPKCFSVLEDVWALYRASHNRELINSVQGFLGRYHQAFSASDPTLSDLPASAQGGPPAVCYICGAELGPGKEFQLSMNPASHLGEKEPFFPFLTVYPPAPRARPADSTGLVATCVLCYHDLLGQWLQHEARAAHQAVSAWSRQYQVDTFVCFFCQQEKKRCLGLKSVRVARLPLFLYTLRASHSLLVDDGRQLIIGACVECGTLVCAGQGLVSQGSMGWSSPAAGATKVTSAPQETPTIVHAPAPEPELQPVPPTDSLSRATRTTQELRPVSSQQSSRDSWDGDGVDLTATGMSHEPKSPSVGMLSTATRTTATVNPLTPSPLNGALVPTGSPATSSTLSAQAAPSSSFAAALRKLAKQAEEPRGSSLSSESSPVSSPATNHSSPASTPKRVPMGPIIVPPGGHSVPSTPPVVTIAPTKTVNGVWRSESRQDSVSRGSSSGRERLLVEPPLAQEKAAGPTIPSHLLSTPYPFGLSPSSVVQDSRFQPLNLQRPVHHVVPPSTVTEDYLRSFRPYHTAEDLRMSSLPPLGLDPATAAAYYHPSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIPTPGSLPPLHPSAMHLHLSGVRYPPELSHSSLAALHSERMSSLSAERLQMDEELRREREREREREREADREREKEREREQREKEREKELEREREKERERELERQREQRAREKDLLAAKALEPTFLPVAELHGLRSHATEERPKPSEQLTPTRAEKLKDVGLQAPKPMQHPLHPVPAPHHTVPSLISSHGIFSLPGNSAATALLIQRTNEEEKWLARQRRLRQEKEDRQSQVSEFRQQVLEQHLDLGRPPVPTEVEHRPESTRPGSNRHDQSSREPPQHFGGPPPLISPKPQHHTVPTALWNPVSLMDNALETRRAESHSLHSHPTAFEPSRPAAVPLVKVERVYCTEKAEEPRKREATPLDKYQPPPRETGSLEPQTFPHGPGPFLAELEKSTQTILSQQRPSLSQATSFGELSGPLKPGSPFCQPTPRGPDPAYIYDEFLQQRRRLVSKLDLEERRRREAQEKGYYYDLDDSYDESDEEEVRAHLRCVAEQPPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRERSPSPPAIQSKRQTPSPRLALSTRYSPDEMNNSPNFEEKRKFLTFFNLTHISAEKRKDRERLVEMLRAMKQRALSAAVADSVTNSSRDSPSISLSEPATQPAPLETDQPAGVPASLSDVPKAVETGRLEQLRPQELLRVQEPAPTSGEKARLSEAPGGKKNLSMLHYLRGAAPKDIPVPLSHSINGKSKPWEPFMAEEFAHQFHESVLQSTQKALQKHKGSSAVLSAEQNHKVDTSVHYNIPELQSSSRVPLPQHNGQQEPPAGRKGPPMQEVDQDSEEDNEDDSEEEAEEAPRRQWQGIEAIFEAYQEHIEEQNLERQVLQTQCRRLEAQNYSLSLTAEQLSHSMAELRSQKQKMVSERERLQAELDHLRKCLALPTMHWPRGYFKGYPR", "length": 1575, "header": "tr|A0A8C2LNG0-1|A0A8C2LNG0_CRIGR Isoform 1 of Genetic suppressor element 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Gse1 PE=4 SV=1 CANONICAL=A0A8C2LNG0-1" }, "locus": {} }, { "isoform_ac": "A0A8C2LQD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNG0/entry#A0A8C2LQD0-1", "sequence": { "sequence": "MKGMSHEPKSPSVGMLSTATRTTATVNPLTPSPLNGALVPTGSPATSSTLSAQAAPSSSFAAALRKLAKQAEEPRGSSLSSESSPVSSPATNHSSPASTPKRVPMGPIIVPPGGHSVPSTPPVVTIAPTKTVNGVWRSESRQDSVSRGSSSGRERLLVEPPLAQEKAAGPTIPSHLLSTPYPFGLSPSSVVQDSRFQPLNLQRPVHHVVPPSTVTEDYLRSFRPYHTAEDLRMSSLPPLGLDPATAAAYYHPSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIPTPGSLPPLHPSAMHLHLSGVRYPPELSHSSLAALHSERMSSLSAERLQMDEELRREREREREREREADREREKEREREQREKEREKELEREREKERERELERQREQRAREKDLLAAKALEPTFLPVAELHGLRSHATEERPKPSEQLTPTRAEKLKDVGLQAPKPMQHPLHPVPAPHHTVPSLISSHGIFSLPGNSAATALLIQRTNEEEKWLARQRRLRQEKEDRQSQVSEFRQQVLEQHLDLGRPPVPTEVEHRPESTRPGSNRHDQSSREPPQHFGGPPPLISPKPQHHTVPTALWNPVSLMDNALETRRAESHSLHSHPTAFEPSRPAAVPLVKVERVYCTEKAEEPRKREATPLDKYQPPPRETGSLEPQTFPHGPGPFLAELEKSTQTILSQQRPSLSQATSFGELSGPLKPGSPFCQPTPRGPDPAYIYDEFLQQRRRLVSKLDLEERRRREAQEKGYYYDLDDSYDESDEEEVRAHLRCVAEQPPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRERSPSPPAIQSKRQTPSPRLALSTRYSPDEMNNSPNFEEKRKFLTFFNLTHISAEKRKDRERLVEMLRAMKQRALSAAVADSVTNSSRDSPSISLSEPATQPAPLETDQPAGVPASLSDVPKAVETGRLEQLRPQELLRVQEPAPTSGEKARLSEAPGGKKNLSMLHYLRGAAPKDIPVPLSHSINGKSKPWEPFMAEEFAHQFHESVLQSTQKALQKHKGSSAVLSAEQNHKVDTSVHYNIPELQSSSRVPLPQHNGQQEPPAGRKGPPMQEVDQDSEEDNEDDSEEEAEEAPRRQWQGIEAIFEAYQEHIEEQNLERQVLQTQCRRLEAQNYSLSLTAEQLSHSMAELRSQKQKMVSERERLQAELDHLRKCLALPTMHWPRGYFKGYPR", "length": 1209, "header": "tr|A0A8C2LQD0-1|A0A8C2LQD0_CRIGR Computationally mapped isoform of Genetic suppressor element 1 isoform X6 OS=Cricetulus griseus OX=10029 GN=Gse1 PE=4 SV=1 CANONICAL=A0A8C2LNG0-1" }, "locus": {} }, { "isoform_ac": "A0A8C2LUE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNG0/entry#A0A8C2LUE5-1", "sequence": { "sequence": "MFGLKPPLYYLPGMSHEPKSPSVGMLSTATRTTATVNPLTPSPLNGALVPTGSPATSSTLSAQAAPSSSFAAALRKLAKQAEEPRGSSLSSESSPVSSPATNHSSPASTPKRVPMGPIIVPPGGHSVPSTPPVVTIAPTKTVNGVWRSESRQDSVSRGSSSGRERLLVEPPLAQEKAAGPTIPSHLLSTPYPFGLSPSSVVQDSRFQPLNLQRPVHHVVPPSTVTEDYLRSFRPYHTAEDLRMSSLPPLGLDPATAAAYYHPSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIPTPGSLPPLHPSAMHLHLSGVRYPPELSHSSLAALHSERMSSLSAERLQMDEELRREREREREREREADREREKEREREQREKEREKELEREREKERERELERQREQRAREKDLLAAKALEPTFLPVAELHGLRSHATEERPKPSEQLTPTRAEKLKDVGLQAPKPMQHPLHPVPAPHHTVPSLISSHGIFSLPGNSAATALLIQRTNEEEKWLARQRRLRQEKEDRQSQVSEFRQQVLEQHLDLGRPPVPTEVEHRPESTRPGSNRHDQSSREPPQHFGGPPPLISPKPQHHTVPTALWNPVSLMDNALETRRAESHSLHSHPTAFEPSRPAAVPLVKVERVYCTEKAEEPRKREATPLDKYQPPPRETGSLEPQTFPHGPGPFLAELEKSTQTILSQQRPSLSQATSFGELSGPLKPGSPFCQPTPRGPDPAYIYDEFLQQRRRLVSKLDLEERRRREAQEKGYYYDLDDSYDESDEEEVRAHLRCVAEQPPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRERSPSPPAIQSKRQTPSPRLALSTRYSPDEMNNSPNFEEKRKFLTFFNLTHISAEKRKDRERLVEMLRAMKQRALSAAVADSVTNSSRDSPSISLSEPATQPAPLETDQPAGVPASLSDVPKAVETGRLEQLRPQELLRVQEPAPTSGEKARLSEAPGGKKNLSMLHYLRGAAPKDIPVPLSHSINGKSKPWEPFMAEEFAHQFHESVLQSTQKALQKHKGSSAVLSAEQNHKVDTSVHYNIPELQSSSRVPLPQHNGQQEPPAGRKGPPMQEVDQDSEEDNEDDSEEEAEEAPRRQWQGIEAIFEAYQEHIEEQNLERQVLQTQCRRLEAQNYSLSLTAEQLSHSMAELRSQKQKMVSERERLQAELDHLRKCLALPTMHWPRGYFKGYPR", "length": 1219, "header": "tr|A0A8C2LUE5-1|A0A8C2LUE5_CRIGR Computationally mapped isoform of Genetic suppressor element 1 isoform X5 OS=Cricetulus griseus OX=10029 GN=Gse1 PE=4 SV=1 CANONICAL=A0A8C2LNG0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FQY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNG0/entry#A0A9J7FQY7-1", "sequence": { "sequence": "MGPIIVPPGGHSVPSTPPVVTIAPTKTVNGVWRSESRQDSVSRGSSSGRERLLVEPPLAQEKAAGPTIPSHLLSTPYPFGLSPSSVVQDSRFQPLNLQRPVHHVVPPSTVTEDYLRSFRPYHTAEDLRMSSLPPLGLDPATAAAYYHPSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIPTPGSLPPLHPSAMHLHLSGVRYPPELSHSSLAALHSERMSSLSAERLQMDEELRREREREREREREADREREKEREREQREKEREKELEREREKERERELERQREQRAREKDLLAAKALEPTFLPVAELHGLRSHATEERPKPSEQLTPTRAEKLKDVGLQAPKPMQHPLHPVPAPHHTVPSLISSHGIFSLPGNSAATALLIQRTNEEEKWLARQRRLRQEKEDRQSQVSEFRQQVLEQHLDLGRPPVPTEVEHRPESTRPGSNRHDQSSREPPQHFGGPPPLISPKPQHHTVPTALWNPVSLMDNALETRRAESHSLHSHPTAFEPSRPAAVPLVKVERVYCTEKAEEPRKREATPLDKYQPPPRETGSLEPQTFPHGPGPFLAELEKSTQTILSQQRPSLSQATSFGELSGPLKPGSPFCQPTPRGPDPAYIYDEFLQQRRRLVSKLDLEERRRREAQEKGYYYDLDDSYDESDEEEVRAHLRCVAEQPPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRERSPSPPAIQSKRQTPSPRLALSTRYSPDEMNNSPNFEEKRKFLTFFNLTHISAEKRKDRERLVEMLRAMKQRALSAAVADSVTNSSRDSPSISLSEPATQPAPLETDQPAGVPASLSDVPKAVETGRLEQLRPQELLRVQEPAPTSGEKARLSEAPGGKKNLSMLHYLRGAAPKDIPVPLSHSINGKSKPWEPFMAEEFAHQFHESVLQSTQKALQKHKGSSAVLSAEQNHKVDTSVHYNIPELQSSSRVPLPQHNGQQEPPAGRKGPPMQEVDQDSEEDNEDDSEEEAEEAPRRQWQGIEAIFEAYQEHIEEQNLERQVLQTQCRRLEAQNYSLSLTAEQLSHSMAELRSQKQKMVSERERLQAELDHLRKCLALPTMHWPRGYFKGYPR", "length": 1105, "header": "tr|A0A9J7FQY7-1|A0A9J7FQY7_CRIGR Computationally mapped isoform of Genetic suppressor element 1 isoform X4 OS=Cricetulus griseus OX=10029 GN=Gse1 PE=4 SV=1 CANONICAL=A0A8C2LNG0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FTH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNG0/entry#A0A9J7FTH3-1", "sequence": { "sequence": "MFGLKPPLYYLPGSSLSSESSPVSSPATNHSSPASTPKRVPMGPIIVPPGGHSVPSTPPVVTIAPTKTVNGVWRSESRQDSVSRGSSSGRERLLVEPPLAQEKAAGPTIPSHLLSTPYPFGLSPSSVVQDSRFQPLNLQRPVHHVVPPSTVTEDYLRSFRPYHTAEDLRMSSLPPLGLDPATAAAYYHPSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIPTPGSLPPLHPSAMHLHLSGVRYPPELSHSSLAALHSERMSSLSAERLQMDEELRREREREREREREADREREKEREREQREKEREKELEREREKERERELERQREQRAREKDLLAAKALEPTFLPVAELHGLRSHATEERPKPSEQLTPTRAEKLKDVGLQAPKPMQHPLHPVPAPHHTVPSLISSHGIFSLPGNSAATALLIQRTNEEEKWLARQRRLRQEKEDRQSQVSEFRQQVLEQHLDLGRPPVPTEVEHRPESTRPGSNRHDQSSREPPQHFGGPPPLISPKPQHHTVPTALWNPVSLMDNALETRRAESHSLHSHPTAFEPSRPAAVPLVKVERVYCTEKAEEPRKREATPLDKYQPPPRETGSLEPQTFPHGPGPFLAELEKSTQTILSQQRPSLSQATSFGELSGPLKPGSPFCQPTPRGPDPAYIYDEFLQQRRRLVSKLDLEERRRREAQEKGYYYDLDDSYDESDEEEVRAHLRCVAEQPPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRERSPSPPAIQSKRQTPSPRLALSTRYSPDEMNNSPNFEEKRKFLTFFNLTHISAEKRKDRERLVEMLRAMKQRALSAAVADSVTNSSRDSPSISLSEPATQPAPLETDQPAGVPASLSDVPKAVETGRLEQLRPQELLRVQEPAPTSGEKARLSEAPGGKKNLSMLHYLRGAAPKDIPVPLSHSINGKSKPWEPFMAEEFAHQFHESVLQSTQKALQKHKGSSAVLSAEQNHKVDTSVHYNIPELQSSSRVPLPQHNGQQEPPAGRKGPPMQEVDQDSEEDNEDDSEEEAEEAPRRQWQGIEAIFEAYQEHIEEQNLERQVLQTQCRRLEAQNYSLSLTAEQLSHSMAELRSQKQKMVSERERLQAELDHLRKCLALPTMHWPRGYFKGYPR", "length": 1146, "header": "tr|A0A9J7FTH3-1|A0A9J7FTH3_CRIGR Computationally mapped isoform of Genetic suppressor element 1 isoform X7 OS=Cricetulus griseus OX=10029 GN=Gse1 PE=4 SV=1 CANONICAL=A0A8C2LNG0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GUC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNG0/entry#A0A9J7GUC9-1", "sequence": { "sequence": "MSHEPKSPSVGMLSTATRTTATVNPLTPSPLNGALVPTGSPATSSTLSAQAAPSSSFAAALRKLAKQAEEPRGSSLSSESSPVSSPATNHSSPASTPKRVPMGPIIVPPGGHSVPSTPPVVTIAPTKTVNGVWRSESRQDSVSRGSSSGRERLLVEPPLAQEKAAGPTIPSHLLSTPYPFGLSPSSVVQDSRFQPLNLQRPVHHVVPPSTVTEDYLRSFRPYHTAEDLRMSSLPPLGLDPATAAAYYHPSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIPTPGSLPPLHPSAMHLHLSGVRYPPELSHSSLAALHSERMSSLSAERLQMDEELRREREREREREREADREREKEREREQREKEREKELEREREKERERELERQREQRAREKDLLAAKALEPTFLPVAELHGLRSHATEERPKPSEQLTPTRAEKLKDVGLQAPKPMQHPLHPVPAPHHTVPSLISSHGIFSLPGNSAATALLIQRTNEEEKWLARQRRLRQEKEDRQSQVSEFRQQVLEQHLDLGRPPVPTEVEHRPESTRPGSNRHDQSSREPPQHFGGPPPLISPKPQHHTVPTALWNPVSLMDNALETRRAESHSLHSHPTAFEPSRPAAVPLVKVERVYCTEKAEEPRKREATPLDKYQPPPRETGSLEPQTFPHGPGPFLAELEKSTQTILSQQRPSLSQATSFGELSGPLKPGSPFCQPTPRGPDPAYIYDEFLQQRRRLVSKLDLEERRRREAQEKGYYYDLDDSYDESDEEEVRAHLRCVAEQPPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRERSPSPPAIQSKRQTPSPRLALSTRYSPDEMNNSPNFEEKRKFLTFFNLTHISAEKRKDRERLVEMLRAMKQRALSAAVADSVTNSSRDSPSISLSEPATQPAPLETDQPAGVPASLSDVPKAVETGRLEQLRPQELLRVQEPAPTSGEKARLSEAPGGKKNLSMLHYLRGAAPKDIPVPLSHSINGKSKPWEPFMAEEFAHQFHESVLQSTQKALQKHKGSSAVLSAEQNHKVDTSVHYNIPELQSSSRVPLPQHNGQQEPPAGRKGPPMQEVDQDSEEDNEDDSEEEAEEAPRRQWQGIEAIFEAYQEHIEEQNLERQVLQTQCRRLEAQNYSLSLTAEQLSHSMAELRSQKQKMVSERERLQAELDHLRKCLALPTMHWPRGYFKGYPR", "length": 1206, "header": "tr|A0A9J7GUC9-1|A0A9J7GUC9_CRIGR Computationally mapped isoform of Genetic suppressor element 1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Gse1 PE=4 SV=1 CANONICAL=A0A8C2LNG0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GYC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNG0/entry#A0A9J7GYC0-1", "sequence": { "sequence": "MKGSSLSSESSPVSSPATNHSSPASTPKRVPMGPIIVPPGGHSVPSTPPVVTIAPTKTVNGVWRSESRQDSVSRGSSSGRERLLVEPPLAQEKAAGPTIPSHLLSTPYPFGLSPSSVVQDSRFQPLNLQRPVHHVVPPSTVTEDYLRSFRPYHTAEDLRMSSLPPLGLDPATAAAYYHPSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIPTPGSLPPLHPSAMHLHLSGVRYPPELSHSSLAALHSERMSSLSAERLQMDEELRREREREREREREADREREKEREREQREKEREKELEREREKERERELERQREQRAREKDLLAAKALEPTFLPVAELHGLRSHATEERPKPSEQLTPTRAEKLKDVGLQAPKPMQHPLHPVPAPHHTVPSLISSHGIFSLPGNSAATALLIQRTNEEEKWLARQRRLRQEKEDRQSQVSEFRQQVLEQHLDLGRPPVPTEVEHRPESTRPGSNRHDQSSREPPQHFGGPPPLISPKPQHHTVPTALWNPVSLMDNALETRRAESHSLHSHPTAFEPSRPAAVPLVKVERVYCTEKAEEPRKREATPLDKYQPPPRETGSLEPQTFPHGPGPFLAELEKSTQTILSQQRPSLSQATSFGELSGPLKPGSPFCQPTPRGPDPAYIYDEFLQQRRRLVSKLDLEERRRREAQEKGYYYDLDDSYDESDEEEVRAHLRCVAEQPPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRERSPSPPAIQSKRQTPSPRLALSTRYSPDEMNNSPNFEEKRKFLTFFNLTHISAEKRKDRERLVEMLRAMKQRALSAAVADSVTNSSRDSPSISLSEPATQPAPLETDQPAGVPASLSDVPKAVETGRLEQLRPQELLRVQEPAPTSGEKARLSEAPGGKKNLSMLHYLRGAAPKDIPVPLSHSINGKSKPWEPFMAEEFAHQFHESVLQSTQKALQKHKGSSAVLSAEQNHKVDTSVHYNIPELQSSSRVPLPQHNGQQEPPAGRKGPPMQEVDQDSEEDNEDDSEEEAEEAPRRQWQGIEAIFEAYQEHIEEQNLERQVLQTQCRRLEAQNYSLSLTAEQLSHSMAELRSQKQKMVSERERLQAELDHLRKCLALPTMHWPRGYFKGYPR", "length": 1136, "header": "tr|A0A9J7GYC0-1|A0A9J7GYC0_CRIGR Computationally mapped isoform of Genetic suppressor element 1 isoform X8 OS=Cricetulus griseus OX=10029 GN=Gse1 PE=4 SV=1 CANONICAL=A0A8C2LNG0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JF52-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNG0/entry#A0A9J7JF52-1", "sequence": { "sequence": 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"predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 332, "start_aa": "Thr", "end_pos": 332, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr332", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 537, "start_aa": "Thr", "end_pos": 537, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr537", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 651, "start_aa": "Thr", "end_pos": 651, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr651", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LNG0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNG0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LNG0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNG0" }, { "id": "PF12540", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12540" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Genetic suppressor element-like", "eco_id": "ECO_0000259", "start_pos": 1092, "end_pos": 1233, "start_aa": "Gln", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 332, 537, 651, 1329 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], 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"https://www.ncbi.nlm.nih.gov/protein/XP_027288567" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027288567", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288567" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LNG1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNG1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rbbp7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNG1", "locus": {} } ], "crossref": [ { "id": "107977000", "url": "https://www.ncbi.nlm.nih.gov/gene/107977000", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050459", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050459", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:107977000", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:107977000", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LNG1", "url": "https://www.orthodb.org/?gene=A0A8C2LNG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22850", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22850", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12265", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12265", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027288567", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027288567", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LNG1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LNG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNG1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASKEMFEDTVEERVINEEYKIWKKNTPFLYDLVMTHALQWPSLTVQWLPEVTKPEGKDYALHWLVLGTHTSDEQNHLVVARVHIPNDDAQFDASHCDSDKGEFGGFGSVTGKIECEIKINHEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVTTSELEGQGS", "length": 425, "header": "tr|A0A8C2LNG1-1|A0A8C2LNG1_CRIGR Isoform 1 of Histone-binding protein RBBP7 isoform X2 OS=Cricetulus griseus OX=10029 GN=Rbbp7 PE=3 SV=1 CANONICAL=A0A8C2LNG1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LNG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNG1/entry#A0A8C2LNG1-1", "sequence": { "sequence": "MASKEMFEDTVEERVINEEYKIWKKNTPFLYDLVMTHALQWPSLTVQWLPEVTKPEGKDYALHWLVLGTHTSDEQNHLVVARVHIPNDDAQFDASHCDSDKGEFGGFGSVTGKIECEIKINHEGEVNRARYMPQNPHIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVTTSELEGQGS", "length": 425, "header": "tr|A0A8C2LNG1-1|A0A8C2LNG1_CRIGR Isoform 1 of Histone-binding protein RBBP7 isoform X2 OS=Cricetulus griseus OX=10029 GN=Rbbp7 PE=3 SV=1 CANONICAL=A0A8C2LNG1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LNG1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNG1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LNG1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNG1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:107977000", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:107977000", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LNG1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNG1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LNG1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNG1" } ], "pmid": "" }, { "name": "DNA replication", "id": "GO:0006260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006260", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LNG1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNG1" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LNG1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNG1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 259, "end_pos": 261, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LNG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNG1" }, { "id": "PF12265", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12265" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Histone-binding protein RBBP4-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 18, "end_pos": 87, "start_aa": "Glu", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 187, "end_pos": 189 }, { "start_pos": 259, "end_pos": 261 }, { "start_pos": 328, "end_pos": 330 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", 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"title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LNL3-1", "uniprot_ac": "A0A8C2LNL3", "uniprot_id": "A0A8C2LNL3_CRIGR", "mass": { "chemical_mass": 101093.0, "monoisotopic_mass": 101093.0 }, "refseq": { "ac": "XP_027289146", "name": "integrator complex subunit 6-like isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027289146" }, "gene_names": [ { "name": "Ints6l", "type": "recommended", "evidence": [ { "id": "A0A8C2LNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNL3" } ] }, { "name": "Ints6l", "type": "synonym", "evidence": [ { "id": "XP_027289146", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027289146" } ] } ], "protein_names": [ { "name": "Integrator complex subunit 6-like isoform X2", "type": "synonym", "evidence": [ { "id": "A0A8C2LNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNL3/entry#names_and_taxonomy" } ] }, { "name": "integrator complex subunit 6-like isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027289146", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027289146" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027289146", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027289146" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LNL3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNL3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ints6l", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNL3", "locus": {} } ], "crossref": [ { "id": "cd00198", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00198", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100768803", "url": "https://www.ncbi.nlm.nih.gov/gene/100768803", "database": "GeneID", "categories": [ "Genome 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"MPILLFLIDTSASMNQRTDLGTSYLDIAKGAVELFLKLRARDPASRGDRYMLVTYDEPPYCIKAGWKENHATFMSELKNLQASGLTTLGQALRSSFDLLNLNRLISGIDNYGQGRNPFFLEPSILITITDGNKLTSTASVQEELHLPLNSPLPGSELTKEPFRWDQRLFALVLRLPGVASTEPEQLGSVPTDESAITQMCEVTGGRSYCVRTQRMLNQCLESLVQKVQSGVVINFEKTGPDPLPVGEDGLMDLCRPSNLFAAQPWHSCHKLIYVRPNSKTGVPVGHWPIPESFWPEQNLPSLPPRTSHPIVRFSCVDCEPMVIDKLPFDKYELEPSPLTQYILERKSPHTCWQVFVTSSGKYNELGYPFGYLKASTTLTCVNLFVMPYNYPVLLPLLDDLFKVHKLKPNLKWRQAFDNYLKTLPPYYLIPLKKALRMMGAPNLISDNLDCGLSYSVISYLKKLSQQTKLESDRILASVGKKPPQEIGIKVKNHSGGGLPLAHNKNFRKLLKEIIGESAPRLTELNTKEFAGFQVGLFNKDLKPQTYRNAYDIPRRGLLDQLTRMRSNLLKTRKFIVGQDEDSLHSVPVAQMGNYQEYLKMLASPLREIDPDQPKRLHTFGNPFKQDKKGMMIDEADEFVVGPQNKVKRPGEPNSPMSSKRRRSMSLLLRKPQTPPTVTNHVGVKGPLSASWFPSCPDLIKPTLVHPDATVIHEIHEEKMENGQSPADGFLLKSAPADFMNVAGDSLISNQLDSLSDDFAGLRKDGLIHKPNNNILIGGAKTCTLSVDDRKIPMASALETVPNSMQITPAMAQGINADIKHQLMKEVRKFGRKYERIFILLEEVQGPLEMKKQFVEFTIKEAARFKRRVLIQYLEKVLEKIDSHHLLNNVNHINSRSSC", "length": 898, "header": "tr|A0A8C2LNL3-1|A0A8C2LNL3_CRIGR Isoform 1 of Integrator complex subunit 6-like isoform X2 OS=Cricetulus griseus OX=10029 GN=Ints6l PE=4 SV=1 CANONICAL=A0A8C2LNL3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LNL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNL3/entry#A0A8C2LNL3-1", "sequence": { "sequence": "MPILLFLIDTSASMNQRTDLGTSYLDIAKGAVELFLKLRARDPASRGDRYMLVTYDEPPYCIKAGWKENHATFMSELKNLQASGLTTLGQALRSSFDLLNLNRLISGIDNYGQGRNPFFLEPSILITITDGNKLTSTASVQEELHLPLNSPLPGSELTKEPFRWDQRLFALVLRLPGVASTEPEQLGSVPTDESAITQMCEVTGGRSYCVRTQRMLNQCLESLVQKVQSGVVINFEKTGPDPLPVGEDGLMDLCRPSNLFAAQPWHSCHKLIYVRPNSKTGVPVGHWPIPESFWPEQNLPSLPPRTSHPIVRFSCVDCEPMVIDKLPFDKYELEPSPLTQYILERKSPHTCWQVFVTSSGKYNELGYPFGYLKASTTLTCVNLFVMPYNYPVLLPLLDDLFKVHKLKPNLKWRQAFDNYLKTLPPYYLIPLKKALRMMGAPNLISDNLDCGLSYSVISYLKKLSQQTKLESDRILASVGKKPPQEIGIKVKNHSGGGLPLAHNKNFRKLLKEIIGESAPRLTELNTKEFAGFQVGLFNKDLKPQTYRNAYDIPRRGLLDQLTRMRSNLLKTRKFIVGQDEDSLHSVPVAQMGNYQEYLKMLASPLREIDPDQPKRLHTFGNPFKQDKKGMMIDEADEFVVGPQNKVKRPGEPNSPMSSKRRRSMSLLLRKPQTPPTVTNHVGVKGPLSASWFPSCPDLIKPTLVHPDATVIHEIHEEKMENGQSPADGFLLKSAPADFMNVAGDSLISNQLDSLSDDFAGLRKDGLIHKPNNNILIGGAKTCTLSVDDRKIPMASALETVPNSMQITPAMAQGINADIKHQLMKEVRKFGRKYERIFILLEEVQGPLEMKKQFVEFTIKEAARFKRRVLIQYLEKVLEKIDSHHLLNNVNHINSRSSC", "length": 898, "header": "tr|A0A8C2LNL3-1|A0A8C2LNL3_CRIGR Isoform 1 of Integrator complex subunit 6-like isoform X2 OS=Cricetulus griseus OX=10029 GN=Ints6l PE=4 SV=1 CANONICAL=A0A8C2LNL3-1" }, "locus": {} }, { "isoform_ac": "A0A8C2LRE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNL3/entry#A0A8C2LRE2-1", "sequence": { "sequence": "MPILLFLIDTSASMNQRTDLGTSYLDIAKGAVELFLKLRARDPASRGDRYMLVTYDEPPYCIKAGWKENHATFMSELKNLQASGLTTLGQALRSSFDLLNLNRLISGIDNYGQGRNPFFLEPSILITITDGNKLTSTASVQEELHLPLNSPLPGSELTKEPFRWDQRLFALVLRLPGVASTEPEQLGSVPTDESAITQMCEVTGGRSYCVRTQRMLNQCLESLVQKVQSGVVINFEKTGPDPLPVGEDGLMDLCRPSNLFAAQPWHSCHKLIYVRPNSKTGVPVGHWPIPESFWPEQNLPSLPPRTSHPIVRFSCVDCEPMVIDKLPFDKYELEPSPLTQYILERKSPHTCWQVFVTSSGKYNELGYPFGYLKASTTLTCVNLFVMPYNYPVLLPLLDDLFKVHKLKPNLKWRQAFDNYLKTLPPYYLITKLESDRILASVGKKPPQEIGIKVKNHSGGGLPLAHNKNFRKLLKEIIGESAPRLTELNTKEFAGFQVGLFNKDLKPQTYRNAYDIPRRGLLDQLTRMRSNLLKTRKFIVGQDEDSLHSVPVAQMGNYQEYLKMLASPLREIDPDQPKRLHTFGNPFKQDKKGMMIDEADEFVVGPQNKVKRPGEPNSPMSSKRRRSMSLLLRKPQTPPTVTNHVGVKGPLSASWFPSCPDLIKPTLVHPDATVIHEIHEEKMENGQSPADGFLLKSAPADFMNVAGDSLISNQLDSLSDDFAGLRKDGLIHKPNNNILIGGAKTCTLSVDDRKIPMASALETVPNSMQITPAMAQGINADIKHQLMKEVRKFGRKYERIFILLEEVQGPLEMKKQFVEFTIKEAARFKRRVLIQYLEKVLEKIDSHHLLNNVNHINSRSSC", "length": 861, "header": "tr|A0A8C2LRE2-1|A0A8C2LRE2_CRIGR Computationally mapped isoform of Integrator complex subunit 6-like isoform X4 OS=Cricetulus griseus OX=10029 GN=Ints6l PE=4 SV=1 CANONICAL=A0A8C2LNL3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GJZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNL3/entry#A0A9J7GJZ9-1", "sequence": { "sequence": "MPILLFLIDTSASMNQRTDLGTSYLDIAKGAVELFLKLRARDPASRGDRYMLVTYDEPPYCIKAGWKENHATFMSELKNLQASGLTTLGQALRSSFDLLNLNRLISGIDNYGQGRNPFFLEPSILITITDGNKLTSTASVQEELHLPLNSPLPGSELTKEPFRWDQRLFALVLRLPGVASTEPEQLGSVPTDESAITQMCEVTGGRSYCVRTQRMLNQCLESLVQKVQSGVVINFEKTGPDPLPVGEDGLMDLCRPSNLFAAQPWHSCHKLIYVRPNSKTGVPVGHWPIPESFWPEQNLPSLPPRTSHPIVRFSCVDCEPMVIDKLPFDKYELEPSPLTQYILERKSPHTCWQVFVTSSGKYNELGYPFGYLKASTTLTCVNLFVMPYNYPVLLPLLDDLFKVHKLKPNLKWRQAFDNYLKTLPPYYLIPLKKALRMMGAPNLISDNLDCGLSYSVISYLKKLSQQTKLESDRILASVGKKPPQEIGIKVKNHSGGGLPLAHNKNFRKLLKEIIGESAPRLTELNTKEFAGFQVGLFNKDLKPQTYRNAYDIPRRGLLDQLTRMRSNLLKTRKFIVGQDEDSLHSVPVAQMGNYQEYLKMLASPLREIDPDQPKRLHTFGNPFKQDKKGMMIDEADEFVVGPQNKVKRPGEPNSPMSSKRRRNATVIHEIHEEKMENGQSPADGFLLKSAPADFMNVAGDSLISNQLDSLSDDFAGLRKDGLIHKPNNNILIGGAKTCTLSVDDRKIPMASALETVPNSMQITPAMAQGINADIKHQLMKEVRKFGRKYERIFILLEEVQGPLEMKKQFVEFTIKEAARFKRRVLIQYLEKVLEKIDSHHLLNNVNHINSRSSC", "length": 854, "header": "tr|A0A9J7GJZ9-1|A0A9J7GJZ9_CRIGR Computationally mapped isoform of Integrator complex subunit 6-like isoform X5 OS=Cricetulus griseus OX=10029 GN=Ints6l PE=4 SV=1 CANONICAL=A0A8C2LNL3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GQ11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNL3/entry#A0A9J7GQ11-1", "sequence": { "sequence": "MPILLFLIDTSASMNQRTDLGTSYLDIAKGAVELFLKLRARDPASRGDRYMLVTYDEPPYCIKAGWKENHATFMSELKNLQASGLTTLGQALRSSFDLLNLNRLISGIDNYGQGRNPFFLEPSILITITDGNKLTSTASVQEELHLPLNSPLPGSELTKEPFRWDQRLFALVLRLPGVASTEPEQLGSVPTDESAITQMCEVTGGRSYCVRTQRMLNQCLESLVQKVQSGVVINFEKTGPDPLPVGEDGLMDLCRPSNLFAAQPWHSCHKLIYVRPNSKTGVPVGHWPIPESFWPEQNLPSLPPRTSHPIVRFSCVDCEPMVIDKLPFDKYELEPSPLTQYILERKSPHTCWQVFVTSSGKYNELGYPFGYLKASTTLTCVNLFVMPYNYPVLLPLLDDLFKVHKLKPNLKWRQAFDNYLKTLPPYYLITKLESDRILASVGKKPPQEIGIKVKNHSGGGLPLAHNKNFRKLLKEIIGESAPRLTELNTKEFAGFQVGLFNKDLKPQTYRNAYDIPRRGLLDQLTRMRSNLLKTRKFIVGQDEDSLHSVPVAQMGNYQEYLKMLASPLREIDPDQPKRLHTFGNPFKQDKKGMMIDEADEFVVGPQNKVKRPGEPNSPMSSKRRRNATVIHEIHEEKMENGQSPADGFLLKSAPADFMNVAGDSLISNQLDSLSDDFAGLRKDGLIHKPNNNILIGGAKTCTLSVDDRKIPMASALETVPNSMQITPAMAQGINADIKHQLMKEVRKFGRKYERIFILLEEVQGPLEMKKQFVEFTIKEAARFKRRVLIQYLEKVLEKIDSHHLLNNVNHINSRSSC", "length": 817, "header": "tr|A0A9J7GQ11-1|A0A9J7GQ11_CRIGR Computationally mapped isoform of Integrator complex subunit 6-like isoform X6 OS=Cricetulus griseus OX=10029 GN=Ints6l PE=4 SV=1 CANONICAL=A0A8C2LNL3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K336-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNL3/entry#A0A9J7K336-1", "sequence": { "sequence": "MNQRTDLGTSYLDIAKGAVELFLKLRARDPASRGDRYMLVTYDEPPYCIKAGWKENHATFMSELKNLQASGLTTLGQALRSSFDLLNLNRLISGIDNYGQGRNPFFLEPSILITITDGNKLTSTASVQEELHLPLNSPLPGSELTKEPFRWDQRLFALVLRLPGVASTEPEQLGSVPTDESAITQMCEVTGGRSYCVRTQRMLNQCLESLVQKVQSGVVINFEKTGPDPLPVGEDGLMDLCRPSNLFAAQPWHSCHKLIYVRPNSKTGVPVGHWPIPESFWPEQNLPSLPPRTSHPIVRFSCVDCEPMVIDKLPFDKYELEPSPLTQYILERKSPHTCWQVFVTSSGKYNELGYPFGYLKASTTLTCVNLFVMPYNYPVLLPLLDDLFKVHKLKPNLKWRQAFDNYLKTLPPYYLIPLKKALRMMGAPNLISDNLDCGLSYSVISYLKKLSQQTKLESDRILASVGKKPPQEIGIKVKNHSGGGLPLAHNKNFRKLLKEIIGESAPRLTELNTKEFAGFQVGLFNKDLKPQTYRNAYDIPRRGLLDQLTRMRSNLLKTRKFIVGQDEDSLHSVPVAQMGNYQEYLKMLASPLREIDPDQPKRLHTFGNPFKQDKKGMMIDEADEFVVGPQNKVKRPGEPNSPMSSKRRRSMSLLLRKPQTPPTVTNHVGVKGPLSASWFPSCPDLIKPTLVHPDATVIHEIHEEKMENGQSPADGFLLKSAPADFMNVAGDSLISNQLDSLSDDFAGLRKDGLIHKPNNNILIGGAKTCTLSVDDRKIPMASALETVPNSMQITPAMAQGINADIKHQLMKEVRKFGRKYERIFILLEEVQGPLEMKKQFVEFTIKEAARFKRRVLIQYLEKVLEKIDSHHLLNNVNHINSRSSC", "length": 885, "header": "tr|A0A9J7K336-1|A0A9J7K336_CRIGR Computationally mapped isoform of Integrator complex subunit 6-like isoform X3 OS=Cricetulus griseus OX=10029 GN=Ints6l PE=4 SV=1 CANONICAL=A0A8C2LNL3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LNL3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNL3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LNL3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNL3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100768803", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100768803", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LNL3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNL3" } ], "pmid": "" }, { "name": "integrator complex", "id": "GO:0032039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032039", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LNL3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNL3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "snRNA 3'-end processing", "id": "GO:0034472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034472", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LNL3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNL3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 492, "end_pos": 494, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LNL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNL3" }, { "id": "PS50234", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50234" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFA", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 227, "start_aa": "Ile", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 492, "end_pos": 494 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LNL8-1", "uniprot_ac": "A0A8C2LNL8", "uniprot_id": "A0A8C2LNL8_CRIGR", "mass": { "chemical_mass": 41735.0, "monoisotopic_mass": 41735.0 }, "refseq": { "ac": "XP_003512778", "name": "actin-related protein T2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512778" }, "gene_names": [ { "name": "LOC100760823", "type": "recommended", "evidence": [ { "id": "A0A8C2LNL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNL8" } ] }, { "name": "LOC100760823", "type": "synonym", "evidence": [ { "id": "XP_003512778", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512778" } ] } ], "protein_names": [ { "name": "Actin-related protein T2", "type": "synonym", "evidence": [ { "id": "A0A8C2LNL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNL8/entry#names_and_taxonomy" } ] }, { "name": "actin-related protein T2", "type": "synonym", "evidence": [ { "id": "XP_003512778", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512778" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615559.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003512778", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512778" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LNL8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNL8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100760823", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNL8", "locus": {} } ], "crossref": [ { "id": "cd13397", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13397", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100760823", "url": "https://www.ncbi.nlm.nih.gov/gene/100760823", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020902", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020902", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760823", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760823", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DQLYQAP", "url": "https://omabrowser.org/oma/group/DQLYQAP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LNL8", "url": "https://www.orthodb.org/?gene=A0A8C2LNL8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11937", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11937", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00022", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00022", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003512778", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512778", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LNL8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LNL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNL8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFNPQVLDSPAVIFDNGSGLCKAGLSGEIGPRHVTSSIVGYPKFKMPSTGANQKKYFVGEEALYKQEALRLHSPIERGLVTSWDDVEKLWRHLFEWELGVKPSERPVLMTEPSLNPRENREKTAEMMFETFDVPAFYLSDQAVLALYASACVTGLVVDSGDGVTCTVPIFEGYSLPHAVSKLYVAGRDITELLTRLLLASGRAFPCPLDKALVDDIKEKLCYVALEPEEELSRRAEDVLREYKLPDGNVIYIGDQLYQAPEVLFSPDQLGTHGPGLAQMASNSIAKCDADIQKTLFGEIVLSGGTTLFQGLDDRLLRELEQLASKGVPIKITAPPDRWFSTWIGASIVTSLISFKQMWITAADFKEFGASVVQRRCF", "length": 377, "header": "tr|A0A8C2LNL8-1|A0A8C2LNL8_CRIGR Isoform 1 of Actin-related protein T2 OS=Cricetulus griseus OX=10029 GN=LOC100760823 PE=3 SV=1 CANONICAL=A0A8C2LNL8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LNL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNL8/entry#A0A8C2LNL8-1", "sequence": { "sequence": "MFNPQVLDSPAVIFDNGSGLCKAGLSGEIGPRHVTSSIVGYPKFKMPSTGANQKKYFVGEEALYKQEALRLHSPIERGLVTSWDDVEKLWRHLFEWELGVKPSERPVLMTEPSLNPRENREKTAEMMFETFDVPAFYLSDQAVLALYASACVTGLVVDSGDGVTCTVPIFEGYSLPHAVSKLYVAGRDITELLTRLLLASGRAFPCPLDKALVDDIKEKLCYVALEPEEELSRRAEDVLREYKLPDGNVIYIGDQLYQAPEVLFSPDQLGTHGPGLAQMASNSIAKCDADIQKTLFGEIVLSGGTTLFQGLDDRLLRELEQLASKGVPIKITAPPDRWFSTWIGASIVTSLISFKQMWITAADFKEFGASVVQRRCF", "length": 377, "header": "tr|A0A8C2LNL8-1|A0A8C2LNL8_CRIGR Isoform 1 of Actin-related protein T2 OS=Cricetulus griseus OX=10029 GN=LOC100760823 PE=3 SV=1 CANONICAL=A0A8C2LNL8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"https://www.ncbi.nlm.nih.gov/protein/XP_003495585" }, "gene_names": [ { "name": "LOC100753465", "type": "recommended", "evidence": [ { "id": "A0A8C2LNN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNN8" } ] }, { "name": "LOC100753465", "type": "synonym", "evidence": [ { "id": "XP_003495585", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495585" } ] } ], "protein_names": [ { "name": "Keratin-associated protein 20-2-like", "type": "synonym", "evidence": [ { "id": "A0A8C2LNN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNN8/entry#names_and_taxonomy" } ] }, { "name": "keratin-associated protein 20-2-like", "type": "synonym", "evidence": [ { "id": "XP_003495585", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495585" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003495585", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495585" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LNN8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNN8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100753465", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNN8", "locus": {} } ], "crossref": [ { "id": "100753465", "url": "https://www.ncbi.nlm.nih.gov/gene/100753465", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR021743", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021743", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100753465", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753465", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR39653", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR39653", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR39653:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR39653:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11759", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11759", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003495585", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495585", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LNN8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LNN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNN8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCYYGRYYGGLGYGYGGLGYGYGCGYGCGSGGYGYGCYRPLCYRRYWSCGFY", "length": 52, "header": "tr|A0A8C2LNN8-1|A0A8C2LNN8_CRIGR Isoform 1 of Keratin-associated protein 20-2-like OS=Cricetulus griseus OX=10029 GN=LOC100753465 PE=4 SV=1 CANONICAL=A0A8C2LNN8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LNN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LNN8/entry#A0A8C2LNN8-1", "sequence": { "sequence": "MCYYGRYYGGLGYGYGGLGYGYGCGYGCGSGGYGYGCYRPLCYRRYWSCGFY", "length": 52, "header": "tr|A0A8C2LNN8-1|A0A8C2LNN8_CRIGR Isoform 1 of Keratin-associated protein 20-2-like OS=Cricetulus griseus OX=10029 GN=LOC100753465 PE=4 SV=1 CANONICAL=A0A8C2LNN8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"A0A8C2LP48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LP48" } ] }, { "name": "Mob1b", "type": "synonym", "evidence": [ { "id": "XP_003510098", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510098" } ] } ], "protein_names": [ { "name": "MOB kinase activator 1B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003510098", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510098" }, { "id": "A0A8C2LP48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LP48/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614817.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003510098", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510098" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LP48", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LP48" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mob1b", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LP48", "locus": {} } ], "crossref": [ { "id": "100751008", "url": "https://www.ncbi.nlm.nih.gov/gene/100751008", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005301", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005301", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036703", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036703", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751008", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751008", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VDNEQMF", "url": "https://omabrowser.org/oma/group/VDNEQMF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LP48", "url": "https://www.orthodb.org/?gene=A0A8C2LP48", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7EXM4", "url": "https://www.orthodb.org/?gene=A0A9J7EXM4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22599", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22599", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03637", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03637", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003510098", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510098", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LP48", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LP48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LP48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LP48-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EXM4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7EXM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7EXM4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR", "length": 216, "header": "tr|A0A8C2LP48-1|A0A8C2LP48_CRIGR Isoform 1 of MOB kinase activator 1B isoform X1 OS=Cricetulus griseus OX=10029 GN=Mob1b PE=4 SV=1 CANONICAL=A0A8C2LP48-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LP48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LP48/entry#A0A8C2LP48-1", "sequence": { "sequence": "MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR", "length": 216, "header": "tr|A0A8C2LP48-1|A0A8C2LP48_CRIGR Isoform 1 of MOB kinase activator 1B isoform X1 OS=Cricetulus griseus OX=10029 GN=Mob1b PE=4 SV=1 CANONICAL=A0A8C2LP48-1" }, "locus": {} }, { "isoform_ac": "A0A9J7EXM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LP48/entry#A0A9J7EXM4-1", "sequence": { "sequence": "MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVQPY", "length": 141, "header": "tr|A0A9J7EXM4-1|A0A9J7EXM4_CRIGR Computationally mapped isoform of MOB kinase activator 1B isoform X2 OS=Cricetulus griseus OX=10029 GN=Mob1b PE=4 SV=1 CANONICAL=A0A8C2LP48-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LP48", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LP48" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LP48", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LP48" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751008", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751008", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XM20-1", "protein_name": "MOB kinase activator 1A", "gene_name": "MOB1B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR", "length": 216 }, "evidence": [ { "id": "A0A8C2LP48", "url": "https://omabrowser.org/oma/group/A0A8C2LP48/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AAA9SNY2-1", "protein_name": "MOB kinase activator 1B", "gene_name": "MOB1B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "VEGATDVNDSGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSGNLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR", "length": 221 }, "evidence": [ { "id": "A0A8C2LP48", "url": "https://omabrowser.org/oma/group/A0A8C2LP48/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54XJ0-1", "protein_name": "MOB kinase activator-like 1 homolog A", "gene_name": "mobA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": 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This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304503", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304503" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LPA8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPA8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Nap1l5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPA8", "locus": {} } ], "crossref": [ { "id": "100754259", "url": "https://www.ncbi.nlm.nih.gov/gene/100754259", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754259", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754259", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ATKPKND", "url": "https://omabrowser.org/oma/group/ATKPKND/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR11875", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11875", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00956", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00956", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304503", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304503", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LPA8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LPA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPA8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MADPEKQGPAESRAEDEVMEGAQGGEDVATGGEGAAAPAAEEPQATGENAPKPKNEFIESLPNSVKCRVLALKKLQKRCDKIEAKFDKEFQALEKKYNDIYKPLLAKIQELTGEMEGCAWTLEEDDDDDEEEDEEEEEEEEEAAAGATGGPDSAKK", "length": 156, "header": "tr|A0A8C2LPA8-1|A0A8C2LPA8_CRIGR Isoform 1 of Nucleosome assembly protein 1-like 5 OS=Cricetulus griseus OX=10029 GN=Nap1l5 PE=3 SV=1 CANONICAL=A0A8C2LPA8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LPA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPA8/entry#A0A8C2LPA8-1", "sequence": { "sequence": "MADPEKQGPAESRAEDEVMEGAQGGEDVATGGEGAAAPAAEEPQATGENAPKPKNEFIESLPNSVKCRVLALKKLQKRCDKIEAKFDKEFQALEKKYNDIYKPLLAKIQELTGEMEGCAWTLEEDDDDDEEEDEEEEEEEEEAAAGATGGPDSAKK", "length": 156, "header": "tr|A0A8C2LPA8-1|A0A8C2LPA8_CRIGR Isoform 1 of Nucleosome assembly protein 1-like 5 OS=Cricetulus griseus OX=10029 GN=Nap1l5 PE=3 SV=1 CANONICAL=A0A8C2LPA8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"MLSCFYRIIRSPRNKRKRSLLLWFELSMAVVIRLLGLPFIAGPVDIRHFFKGLTIPDGGVHIIGGKVGEAFIIFATDEDARRAISRSGGFIKDSSVELFLSSKAEMQKTIEMKRTARGGRGRLGSGASGASSLYHFIDAMKEEESYSGYGSSINQDAGFHTNGTGLDIRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFFSGLCVDGVIFLKHHDGRNNGDAVVKFASCIDASGGLKCHRSFMGSRFIEVMQGSEQQWIEFGGNAAKGGDVPCMRAEEHSPSRGMNDRYFRKRTHSKSPRRTRSRSPLGFYLHLKNLSLSIDKRDLRNFFKDTDLTNEQIKFLYKDERRTRYAFVMFKNLKDYNTALGLHKTVLQYRPVFIDPISRKQMVKFIECYEKKRPGSVEKGRPGRVSQKFFEEGYSGQKLYIYIRNFPFDVTKVEVQKFFVDFSLVENDIYLLYDDKGVGLGEALVRFKSEEQAMKAERLNRRRFLGTEVLLRLISEVQMQEFGVNFSFMCNEKTQACSQSHNRDDHSRLFDLKDSPLCSLGRSESVGYQPEDLRHPHRYFQQSDKRPLEDFRHSPEDFRHSPEDYRHPQEEHIRCSREEAWRRPLEDWRWSPEDDFRHSHEKDFRQLPEDDFTFSWEDFRRPPQEHFRRPSQEHFRRPPQEHFRLSREEYFRHMVDEDYRHPSDEDFRTQEEDLRCPTDEDFRQVSGEDLREVSEDSLRVPDSFRSPGEEFWTSPDFRDHHPFMNFGHLEGGKFDFGKHNIGCVPEGRFMPDLKLNCSSGRITPVKIMNLPFKANANEILDFFHGYKVIPDSVSIQYNEQGLPIGEAIIAMINYNEAIAAIKELNGRPVGPRKVKLILL", "length": 867, "header": "tr|A0A8C2LPG5-1|A0A8C2LPG5_CRIGR Isoform 1 of RNA-binding protein 12B isoform X2 OS=Cricetulus griseus OX=10029 GN=Rbm12b PE=4 SV=1 CANONICAL=A0A8C2LPG5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LPG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPG5/entry#A0A8C2LPG5-1", "sequence": { "sequence": "MLSCFYRIIRSPRNKRKRSLLLWFELSMAVVIRLLGLPFIAGPVDIRHFFKGLTIPDGGVHIIGGKVGEAFIIFATDEDARRAISRSGGFIKDSSVELFLSSKAEMQKTIEMKRTARGGRGRLGSGASGASSLYHFIDAMKEEESYSGYGSSINQDAGFHTNGTGLDIRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFFSGLCVDGVIFLKHHDGRNNGDAVVKFASCIDASGGLKCHRSFMGSRFIEVMQGSEQQWIEFGGNAAKGGDVPCMRAEEHSPSRGMNDRYFRKRTHSKSPRRTRSRSPLGFYLHLKNLSLSIDKRDLRNFFKDTDLTNEQIKFLYKDERRTRYAFVMFKNLKDYNTALGLHKTVLQYRPVFIDPISRKQMVKFIECYEKKRPGSVEKGRPGRVSQKFFEEGYSGQKLYIYIRNFPFDVTKVEVQKFFVDFSLVENDIYLLYDDKGVGLGEALVRFKSEEQAMKAERLNRRRFLGTEVLLRLISEVQMQEFGVNFSFMCNEKTQACSQSHNRDDHSRLFDLKDSPLCSLGRSESVGYQPEDLRHPHRYFQQSDKRPLEDFRHSPEDFRHSPEDYRHPQEEHIRCSREEAWRRPLEDWRWSPEDDFRHSHEKDFRQLPEDDFTFSWEDFRRPPQEHFRRPSQEHFRRPPQEHFRLSREEYFRHMVDEDYRHPSDEDFRTQEEDLRCPTDEDFRQVSGEDLREVSEDSLRVPDSFRSPGEEFWTSPDFRDHHPFMNFGHLEGGKFDFGKHNIGCVPEGRFMPDLKLNCSSGRITPVKIMNLPFKANANEILDFFHGYKVIPDSVSIQYNEQGLPIGEAIIAMINYNEAIAAIKELNGRPVGPRKVKLILL", "length": 867, "header": "tr|A0A8C2LPG5-1|A0A8C2LPG5_CRIGR Isoform 1 of RNA-binding protein 12B isoform X2 OS=Cricetulus griseus OX=10029 GN=Rbm12b PE=4 SV=1 CANONICAL=A0A8C2LPG5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FHG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPG5/entry#A0A9J7FHG3-1", "sequence": { "sequence": "MAVVIRLLGLPFIAGPVDIRHFFKGLTIPDGGVHIIGGKVGEAFIIFATDEDARRAISRSGGFIKDSSVELFLSSKAEMQKTIEMKRTARGGRGRLGSGASGASSLYHFIDAMKEEESYSGYGSSINQDAGFHTNGTGLDIRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFFSGLCVDGVIFLKHHDGRNNGDAVVKFASCIDASGGLKCHRSFMGSRFIEVMQGSEQQWIEFGGNAAKGGDVPCMRAEEHSPSRGMNDRYFRKRTHSKSPRRTRSRSPLGFYLHLKNLSLSIDKRDLRNFFKDTDLTNEQIKFLYKDERRTRYAFVMFKNLKDYNTALGLHKTVLQYRPVFIDPISRKQMVKFIECYEKKRPGSVEKGRPGRVSQKFFEEGYSGQKLYIYIRNFPFDVTKVEVQKFFVDFSLVENDIYLLYDDKGVGLGEALVRFKSEEQAMKAERLNRRRFLGTEVLLRLISEVQMQEFGVNFSFMCNEKTQACSQSHNRDDHSRLFDLKDSPLCSLGRSESVGYQPEDLRHPHRYFQQSDKRPLEDFRHSPEDFRHSPEDYRHPQEEHIRCSREEAWRRPLEDWRWSPEDDFRHSHEKDFRQLPEDDFTFSWEDFRRPPQEHFRRPSQEHFRRPPQEHFRLSREEYFRHMVDEDYRHPSDEDFRTQEEDLRCPTDEDFRQVSGEDLREVSEDSLRVPDSFRSPGEEFWTSPDFRDHHPFMNFGHLEGGKFDFGKHNIGCVPEGRFMPDLKLNCSSGRITPVKIMNLPFKANANEILDFFHGYKVIPDSVSIQYNEQGLPIGEAIIAMINYNEAIAAIKELNGRPVGPRKVKLILL", "length": 840, "header": "tr|A0A9J7FHG3-1|A0A9J7FHG3_CRIGR Computationally mapped isoform of RNA-binding protein 12B isoform X3 OS=Cricetulus griseus OX=10029 GN=Rbm12b PE=4 SV=1 CANONICAL=A0A8C2LPG5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LPG5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPG5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LPG5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPG5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762542", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762542", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LPG5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPG5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" }, { "start_pos": 513, "end_pos": 515, "annotation": "n_glycosylation_sequon" }, { "start_pos": 784, "end_pos": 786, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LPG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPG5" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 181, "end_pos": 256, "start_aa": "Pro", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 162, "end_pos": 164 }, { "start_pos": 317, "end_pos": 319 }, { "start_pos": 513, "end_pos": 515 }, { "start_pos": 784, "end_pos": 786 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LPV7-1", "uniprot_ac": "A0A8C2LPV7", "uniprot_id": "A0A8C2LPV7_CRIGR", "mass": { "chemical_mass": 6428.0, "monoisotopic_mass": 6428.0 }, "refseq": { "ac": "XP_003507880", "name": "cytochrome c oxidase assembly protein COX14", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507880" }, "gene_names": [ { "name": "LOC100772471", "type": "recommended", "evidence": [ { "id": "A0A8C2LPV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPV7" } ] }, { "name": "LOC100772471", "type": "synonym", "evidence": [ { "id": "XP_003507880", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507880" } ] } ], "protein_names": [ { "name": "Cytochrome c oxidase assembly protein COX14", "type": "synonym", "evidence": [ { "id": "A0A8C2LPV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPV7/entry#names_and_taxonomy" } ] }, { "name": "cytochrome c oxidase assembly protein COX14", "type": "synonym", "evidence": [ { "id": "XP_003507880", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507880" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614438.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003507880", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507880" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LPV7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPV7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100772471", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPV7", "locus": {} } ], "crossref": [ { "id": "100772471", "url": "https://www.ncbi.nlm.nih.gov/gene/100772471", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029208", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029208", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772471", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772471", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VYHYFQR", "url": "https://omabrowser.org/oma/group/VYHYFQR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LPV7", "url": "https://www.orthodb.org/?gene=A0A8C2LPV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR36684", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36684", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR36684:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36684:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14880", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14880", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003507880", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003507880", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LPV7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LPV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPV7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPTAKQLADIGYKTFSASMMLLTVYGGYLCSVRAYRYFQLRSARRQAAEEQKTSGVL", "length": 57, "header": "tr|A0A8C2LPV7-1|A0A8C2LPV7_CRIGR Isoform 1 of Cytochrome c oxidase assembly protein COX14 OS=Cricetulus griseus OX=10029 GN=LOC100772471 PE=4 SV=1 CANONICAL=A0A8C2LPV7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LPV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPV7/entry#A0A8C2LPV7-1", "sequence": { "sequence": "MPTAKQLADIGYKTFSASMMLLTVYGGYLCSVRAYRYFQLRSARRQAAEEQKTSGVL", "length": 57, "header": "tr|A0A8C2LPV7-1|A0A8C2LPV7_CRIGR Isoform 1 of Cytochrome c oxidase assembly protein COX14 OS=Cricetulus griseus OX=10029 GN=LOC100772471 PE=4 SV=1 CANONICAL=A0A8C2LPV7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LPV7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPV7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LPV7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPV7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100772471", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772471", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1A933-1", "protein_name": "COX14, cytochrome c oxidase assembly factor", "gene_name": "COX14", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVSGKQLADFGYKAFSGSMMLLTVYGGYLCGVRAYRLLQNRRARQASAGPES", "length": 52 }, "evidence": [ { "id": "A0A8C2LPV7", "url": "https://omabrowser.org/oma/group/A0A8C2LPV7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q1RMH3-1", "protein_name": "Cytochrome c oxidase assembly protein COX14", "gene_name": "COX14", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPTAKQLADIGYKTFSTSMMLLTVYGGYLCSVRAYHYFQRRSSRRQAAEEQKTSGAL", "length": 57 }, "evidence": [ { "id": "A0A8C2LPV7", "url": "https://omabrowser.org/oma/group/A0A8C2LPV7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8BH51-1", "protein_name": "Cytochrome c oxidase assembly protein COX14", "gene_name": "Cox14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPSAKQLADIGYKTFSASMMLLTVYGGYLCSVRAYRYLQLRSARRQAAEEQKTSGVL", "length": 57 }, "evidence": [ { "id": "A0A8C2LPV7", "url": "https://omabrowser.org/oma/group/A0A8C2LPV7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96I36-1", "protein_name": "Cytochrome c oxidase assembly protein COX14", "gene_name": "COX14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614849.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007649035", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649035" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LPX4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPX4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Kctd6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPX4", "locus": {} } ], "crossref": [ { "id": "cd18394", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18394", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100765751", "url": "https://www.ncbi.nlm.nih.gov/gene/100765751", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765751", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765751", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FTIRMTR", "url": "https://omabrowser.org/oma/group/FTIRMTR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LPX4", "url": "https://www.orthodb.org/?gene=A0A8C2LPX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14499", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14499", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14499:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14499:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02214", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02214", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007649035", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007649035", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LPX4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LPX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPX4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDNGDWGYMMTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEVVELSSTRKLSKYSNPVAVIITQLTITTKVHSLLEGISNYFTKWNKHMMDTRDCQVSFTFGPCDYHQEVSLRVHLMEYITKQGFTIRNTRVHHMSERANENTVEHNWTFCRLARKTDD", "length": 237, "header": "tr|A0A8C2LPX4-1|A0A8C2LPX4_CRIGR Isoform 1 of BTB/POZ domain-containing protein KCTD6 isoform X2 OS=Cricetulus griseus OX=10029 GN=Kctd6 PE=4 SV=1 CANONICAL=A0A8C2LPX4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LPX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPX4/entry#A0A8C2LPX4-1", "sequence": { "sequence": "MDNGDWGYMMTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEVVELSSTRKLSKYSNPVAVIITQLTITTKVHSLLEGISNYFTKWNKHMMDTRDCQVSFTFGPCDYHQEVSLRVHLMEYITKQGFTIRNTRVHHMSERANENTVEHNWTFCRLARKTDD", "length": 237, "header": "tr|A0A8C2LPX4-1|A0A8C2LPX4_CRIGR Isoform 1 of BTB/POZ domain-containing protein KCTD6 isoform X2 OS=Cricetulus griseus OX=10029 GN=Kctd6 PE=4 SV=1 CANONICAL=A0A8C2LPX4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LPX4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LPX4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765751", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765751", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1VK23-1", "protein_name": "Potassium channel tetramerization domain containing 6", "gene_name": "KCTD6", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDNGDWGYMMTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEVVELSSTRKLSKYSNPVAVIITQLTITTKVHSLLEGISNYFTKWNKHMMDTRDCQVSFTFGPCDYHQEVSLRVHLMEYITKQGFTIRNTRVHHMSERANENTVEHNWTFCRLARKTDD", "length": 237 }, "evidence": [ { "id": "A0A8C2LPX4", "url": 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This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. 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Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003627193.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035294459", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294459" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LQ23", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQ23" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ctxnd1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQ23", "locus": {} } ], "crossref": [ { "id": "113832053", "url": "https://www.ncbi.nlm.nih.gov/gene/113832053", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR020066", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020066", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113832053", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113832053", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WIVSIME", "url": "https://omabrowser.org/oma/group/WIVSIME/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LQ23", "url": "https://www.orthodb.org/?gene=A0A8C2LQ23", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16736", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16736", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16736:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16736:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035294459", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294459", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LQ23", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQ23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LQ23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQ23-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEEPTPEPVYVDVDKGLTLACFVFLCLFLIVMIIRCAKVIMDPYSAIPTSTWEEQHLDD", "length": 59, "header": "tr|A0A8C2LQ23-1|A0A8C2LQ23_CRIGR Isoform 1 of Cortexin domain-containing 1 OS=Cricetulus griseus OX=10029 GN=Ctxnd1 PE=4 SV=1 CANONICAL=A0A8C2LQ23-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LQ23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQ23/entry#A0A8C2LQ23-1", "sequence": { "sequence": "MEEPTPEPVYVDVDKGLTLACFVFLCLFLIVMIIRCAKVIMDPYSAIPTSTWEEQHLDD", "length": 59, "header": "tr|A0A8C2LQ23-1|A0A8C2LQ23_CRIGR Isoform 1 of Cortexin domain-containing 1 OS=Cricetulus griseus OX=10029 GN=Ctxnd1 PE=4 SV=1 CANONICAL=A0A8C2LQ23-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 13% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027274414", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027274414" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LQH8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQH8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tmed8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQH8", "locus": {} } ], "crossref": [ { "id": "100764153", "url": "https://www.ncbi.nlm.nih.gov/gene/100764153", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009038", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009038", "database": "InterPro", "categories": [ "Protein Classification" ] 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This record is derived from a genomic sequence (NW_003613589.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003495370", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495370" } ] }, { "annotation": "May be involved in neurite outgrowth.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LQJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQJ1#function" }, { "database": "UniProtKB", "id": "ARBA00002358", "url": "https://www.uniprot.org/uniprotkb/ARBA00002358#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LQJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQJ1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Gprin2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQJ1", "locus": {} } ], "crossref": [ { "id": "100773657", "url": "https://www.ncbi.nlm.nih.gov/gene/100773657", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026646", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026646", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032745", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032745", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773657", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773657", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VWQAQPG", "url": "https://omabrowser.org/oma/group/VWQAQPG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LQJ1", "url": "https://www.orthodb.org/?gene=A0A8C2LQJ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15718", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15718", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15718:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15718:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15235", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15235", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003495370", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495370", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LQJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LQJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSSHPEPGARESQSPRPQPLSQSSSSLLCEGREQRPELRKSASSTVWQAQPGEASPSPRTLEEEGCQTESMDQAQTSSPWPQPGAGGHWRSSTVGNVSTMGIGDLCRLRAPSVAAVQRSHSDLVHSTQTRGHGSAQKASLSCSALGSSPVQTAQLQLGSVAGQDGQTPGVLQSDLAPEDGTSTSACILGESQVLVPTVELEGTAGLISSPQGGPKATGQPPTTSCQVLPPAALLCTVRETASGGCYHALPATGILAFPKLVASVSESGLQAQCGMKFHCKLPGGISGHPHCCVHPWGPTGLATESGSRTKDVWTMTSATDLALGVASAQDAGVQVAPVAACKAVATSPSLEEPETQNIFPEVMLGAGLEKASSPVREVRWDAEGMTWEVYGASVDPEVLGIAIQKHLEMQFEQLQQAPASEDSLSTEGRRGPLRAVMQSLRRPSCCGCSGAAPE", "length": 455, "header": "tr|A0A8C2LQJ1-1|A0A8C2LQJ1_CRIGR Isoform 1 of G protein-regulated inducer of neurite outgrowth 2 OS=Cricetulus griseus OX=10029 GN=Gprin2 PE=4 SV=1 CANONICAL=A0A8C2LQJ1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LQJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQJ1/entry#A0A8C2LQJ1-1", "sequence": { "sequence": "MSSSHPEPGARESQSPRPQPLSQSSSSLLCEGREQRPELRKSASSTVWQAQPGEASPSPRTLEEEGCQTESMDQAQTSSPWPQPGAGGHWRSSTVGNVSTMGIGDLCRLRAPSVAAVQRSHSDLVHSTQTRGHGSAQKASLSCSALGSSPVQTAQLQLGSVAGQDGQTPGVLQSDLAPEDGTSTSACILGESQVLVPTVELEGTAGLISSPQGGPKATGQPPTTSCQVLPPAALLCTVRETASGGCYHALPATGILAFPKLVASVSESGLQAQCGMKFHCKLPGGISGHPHCCVHPWGPTGLATESGSRTKDVWTMTSATDLALGVASAQDAGVQVAPVAACKAVATSPSLEEPETQNIFPEVMLGAGLEKASSPVREVRWDAEGMTWEVYGASVDPEVLGIAIQKHLEMQFEQLQQAPASEDSLSTEGRRGPLRAVMQSLRRPSCCGCSGAAPE", "length": 455, "header": "tr|A0A8C2LQJ1-1|A0A8C2LQJ1_CRIGR Isoform 1 of G protein-regulated inducer of neurite outgrowth 2 OS=Cricetulus griseus OX=10029 GN=Gprin2 PE=4 SV=1 CANONICAL=A0A8C2LQJ1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LQJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQJ1" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LQJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQJ1" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773657", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773657", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2I3BRN2-1", "protein_name": "G protein regulated inducer of neurite outgrowth 2", "gene_name": "Gprin2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSSHPEPGAREPQSPRPQALSQSSSSLLCEGREQKPELRKSASSTVWRAQQGEAGSSPRILQEEACQTEIPEHAQTASTASQAGAGGHWRSSTVGNVSTMGIGDLCRLRAPSVAAVQRSHSDLVHSTQTRGHGGVQKPSLSCSALGSSPVHRAQLQPGSVAGQGGQTPAPLQSDSAPEDGTSKSACTLGESQVWVPTVELEDATGLLRGPQGEPKATGQPPTTSCHALPPAALLCTLGEAVAGSCCHALPARGILAFPKLVASVSESGLQAQCGMKFHCKLSGGISGHPHCCVHPWGPTGLATESGSRTKDVWTMTSATDLALGVASAQDAGVQAAPAAACKAVATSPSLEAPETLNLFPEVMLESGLRQASSPVRDVRWDAEGMTWEVYGASVDPEVLGIAIQKHLEMQFEQLQQAPASEDSLSAEGRRGPLRAVMQSLRRPSCCGCSGAAPE", "length": 455 }, "evidence": [ { "id": "A0A8C2LQJ1", "url": "https://omabrowser.org/oma/group/A0A8C2LQJ1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZH78-1", "protein_name": "G protein regulated inducer of neurite outgrowth 2", "gene_name": "Gprin2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"MRSSRPEPDAPEPLSAHPQPLSRSSSSLLGEGRGQRPEYRKRASSTVCQAQLGEAGTGAQVPEAEGQQAERVEQAQASSPQLQPSAVGHWRSSTVGNVSTVGGSDLCNPWDPSAAAVQRSHSDLAHSTQTRGHSGAQKASLSCSALGSLPVHGAQLQPSSTSGQSGQTPEGLERDLAPEDKTSNSAWTLESQVWVPPAALGGTVTHSSSPKATGQSATTSCHALSPAALLCGMREVGASSCCHGLPAPGILAFPKLVASVSESRLQAHHGVKLQCRFSGGLPGHSHCCAHPWGPTGLAMEPSARTKDMWTMTSASDLAPVLASPLSAQDAGVQAAPKAVCKAVATSPPLEAPVALRMFPEVTLEPSLAEAPSPVRDVRWDAEGMTWEVYGAAVDPEVLGVAIQKHLEMQFEQLQGAPASEDSLSAEGRRGPLRAVMQSLRHPSCCGCSSAAPE", "length": 453 }, "evidence": [ { "id": "A0A8C2LQJ1", "url": "https://omabrowser.org/oma/group/A0A8C2LQJ1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O60269-1", "protein_name": "G protein-regulated inducer of neurite outgrowth 2", "gene_name": "GPRIN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"start_pos": 369, "end_pos": 447, "start_aa": "Leu", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 97, "end_pos": 99 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": 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This record is derived from a genomic sequence (NW_003615310.1) and transcript sequence (IACG01142236.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035292538", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035292538" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LQR3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQR3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC118237589", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQR3", "locus": {} } ], "crossref": [ { "id": "cd02961", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02961", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "118237589", "url": "https://www.ncbi.nlm.nih.gov/gene/118237589", "database": "GeneID", "categories": [ 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"https://www.genome.jp/dbget-bin/www_bget?cge:118237589", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LQR3", "url": "https://www.orthodb.org/?gene=A0A8C2LQR3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22699", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22699", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22699:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22699:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00085", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00085", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13848", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13848", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24508", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24508", 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CANONICAL=A0A8C2LQR3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LQR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQR3/entry#A0A8C2LQR3-1", "sequence": { "sequence": "MMSSDFVVFRAGVALVLMCSFYKSTEDPLPELSPQQYFSTLQPGKASLAYFCQVGSLSNSLFLEELKEAIRPLQDYGISVSKVNCVKEEASRYCGKEEALMKAYLFRGNILLREFPTDTLFDVNAIVAHVLFALLFNEVKYVTTLEDLHSIENSLKGKANMIFSYVEAIGTPEHRAVMEAAFVYGTSYQFALTTEFALLENIGSENIDRAHLYFFHCKVVLDLTEHCRTTQMEQPLTTLNIHVFVKTMKAPLLTEVAEDPQQVSTIHLQLGLPLVFIISQQATYEADRRTAEWVAWRLLGKAGVLLLSRDSVDMDIPQHANVAFRRAEKEVPVEFLVLNDVDLIVSYVENNMYIEEIQEDEDGVQKGPDLAIQDDEVAETVYRDRKRPLPLELTVELTQETFNSTVTTSDSLVLFYATWHAVSMAFLQSYIDVAIKLKGTSTILLTRINCADWSDVCSKQNVTAFPAVKLYKEGESPVSYEGMLGTKDLLKFVQLNRISCPVNIASIQEAEKYLCGELYKDLLSFTSVSVLGLFSPAMTSAKEHFREVGKQLRGSVITGVYSEDDVWILSNKYAAPLPAMLLARPREGRIESVPLATAPVQEMVQILANAPLEAFPEITVENLPAYLRLQRPLLILFSDGSINPQYRNTTLALVRQKQLDSFTPCWLNLKNTPVGRGILKAYFGHLPPLPQLLLVNLHSGGQVYAFPSAQSITEQNLILWLKKLEAGLENPITILSDQEWKPPLPAFDFLSMMDAPTSQAPTKKVEECMKEAEGQETAEQPQGGKSATRRLPTEMLRIKHWNRSNWPKEAAEEPSQLHREL", "length": 821, "header": "tr|A0A8C2LQR3-1|A0A8C2LQR3_CRIGR Isoform 1 of Thioredoxin domain-containing protein 16 OS=Cricetulus griseus OX=10029 GN=LOC118237589 PE=4 SV=1 CANONICAL=A0A8C2LQR3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LQR3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQR3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LQR3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQR3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:118237589", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:118237589", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LQR3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQR3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" }, { "start_pos": 461, "end_pos": 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LR21-1", "uniprot_ac": "A0A8C2LR21", "uniprot_id": "A0A8C2LR21_CRIGR", "mass": { "chemical_mass": 117399.0, "monoisotopic_mass": 117399.0 }, "refseq": { "ac": "XP_027285539", "name": "probable E3 ubiquitin-protein ligase HERC3 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285539" }, "gene_names": [ { "name": "LOC100761790", "type": "recommended", "evidence": [ { "id": "A0A8C2LR21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LR21" } ] }, { "name": "LOC100761790", "type": "synonym", "evidence": [ { "id": "XP_027285539", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285539" } ] } ], "protein_names": [ { "name": "Probable E3 ubiquitin-protein ligase HERC3 isoform X3", "type": "synonym", "evidence": [ { "id": "A0A8C2LR21", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LR21/entry#names_and_taxonomy" } ] }, { "name": "probable E3 ubiquitin-protein ligase HERC3 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027285539", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285539" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027285539", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285539" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LR21", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LR21" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100761790", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LR21", "locus": {} } ], "crossref": [ { "id": "cd00078", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00078", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100761790", "url": "https://www.ncbi.nlm.nih.gov/gene/100761790", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000408", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000408", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009091", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009091", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051709", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051709", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058923", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058923", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761790", "url": 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"Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027285539", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027285539", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LR21", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LR21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LR21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LR21-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K0M3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K0M3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K0M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K0M3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 1050, "header": "tr|A0A8C2LR21-1|A0A8C2LR21_CRIGR Isoform 1 of Probable E3 ubiquitin-protein ligase HERC3 isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC100761790 PE=4 SV=1 CANONICAL=A0A8C2LR21-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K0M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LR21/entry#A0A9J7K0M3-1", "sequence": { "sequence": "MLCWGYWSLGQPGISSNLRGIVAEPQVCRFVSDRSIKEVACGGNHSVFLLEDGEVYTCGVNSKGQLGHEREGNKPEQIGALADQHIVHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQTSPQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHGSMNDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFKYRVVKQIFSGGDQTFVLCSTYENSSPAVDFRTVNQTHYTHLINDETLAIWRQKLSEHNNANTMNGVVQILSSAACWNGSFLEKKIDEHFKTSSKIPGIDLNSTRVLFEKLMHSQHSVILEQILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNPSKVLDNWWSQSCPKYFLRLVTLYKDAVLYLLKGRKTFLIPVVFTSYVTAALKLLKKLYKVNLRVKHVEYDKFYIPEISSLVDIQEDYLMWFLHQAGMKPRPSIMQDSVTLCSYPFIFDAQAKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNHLVGDALRELSIHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSQLLWFSDTCFVERNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQELLDYPGEDVEETFCLNFTVCRESYGVIKQKKLIPGGDRVAVRKDNRYFATRLEEARIKIYPSDN", "length": 904, "header": "tr|A0A9J7K0M3-1|A0A9J7K0M3_CRIGR Computationally mapped isoform of Probable E3 ubiquitin-protein ligase HERC3 isoform X4 OS=Cricetulus griseus OX=10029 GN=LOC100761790 PE=4 SV=1 CANONICAL=A0A8C2LR21-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LR21", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LR21" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LR21", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LR21" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761790", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761790", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LR21", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LR21" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LR21", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LR21" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LR21", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LR21" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LR21", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LR21" } ], "pmid": "" }, { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LR21", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LR21" } ], "pmid": "" } ] } ] }, "pro_annotation": [], 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{ "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LR53-1", "uniprot_ac": "A0A8C2LR53", "uniprot_id": 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"https://www.ncbi.nlm.nih.gov/protein/XP_027268053" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027268053", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268053" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LR53", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LR53" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100772302", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LR53", "locus": {} } ], "crossref": [ { "id": "100772302", "url": "https://www.ncbi.nlm.nih.gov/gene/100772302", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772302", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772302", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LR53", "url": "https://www.orthodb.org/?gene=A0A8C2LR53", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48018", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48018", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027268053", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268053", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LR53", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LR53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LR53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LR53-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSVNVSLVTEFILVGLTDRPELQMPLFFVFLTMYVVTALGNLCLIILTVVNSNLHTPMYFFLFNLSFVDLFYCSVFTLQMLMNFILRKKVISYMECMTQVFFFSFFVVSECYVLTSMAYDCYMAICNPLLYNVVMSPKLCLNLMLGCYFIAFSNAVAHTVCMLRLTFCDGNTINHYFCDIPPLLQLSCTSTYVNKLVIFVLGGISIIVPTSTIFVSYGFILSSIFHISSSEGRSKAFSTCSSHVFAVFLFFGSGAFVYFKPSSAGSMNEAKISSVTYTNVVPMLNPLVYSLRNKDIKFALRKTLSSWKF", "length": 310, "header": "tr|A0A8C2LR53-1|A0A8C2LR53_CRIGR Isoform 1 of Olfactory receptor 8B3-like OS=Cricetulus griseus OX=10029 GN=LOC100772302 PE=3 SV=1 CANONICAL=A0A8C2LR53-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LR53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LR53/entry#A0A8C2LR53-1", "sequence": { "sequence": "MDSVNVSLVTEFILVGLTDRPELQMPLFFVFLTMYVVTALGNLCLIILTVVNSNLHTPMYFFLFNLSFVDLFYCSVFTLQMLMNFILRKKVISYMECMTQVFFFSFFVVSECYVLTSMAYDCYMAICNPLLYNVVMSPKLCLNLMLGCYFIAFSNAVAHTVCMLRLTFCDGNTINHYFCDIPPLLQLSCTSTYVNKLVIFVLGGISIIVPTSTIFVSYGFILSSIFHISSSEGRSKAFSTCSSHVFAVFLFFGSGAFVYFKPSSAGSMNEAKISSVTYTNVVPMLNPLVYSLRNKDIKFALRKTLSSWKF", "length": 310, "header": "tr|A0A8C2LR53-1|A0A8C2LR53_CRIGR Isoform 1 of Olfactory receptor 8B3-like OS=Cricetulus griseus OX=10029 GN=LOC100772302 PE=3 SV=1 CANONICAL=A0A8C2LR53-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035298941", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298941" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LRC2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRC2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100759821", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRC2", "locus": {} } ], "crossref": [ { "id": "100759821", "url": "https://www.ncbi.nlm.nih.gov/gene/100759821", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759821", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759821", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TMCCLDM", "url": "https://omabrowser.org/oma/group/TMCCLDM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LRC2", "url": "https://www.orthodb.org/?gene=A0A8C2LRC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24237", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24237", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24237:SF40", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24237:SF40", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035298941", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298941", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LRC2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LRC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRC2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDMMNGTTVSNVSSIDQDHCDAYCRTTLITAYSVVLFGGTIGTVMMSRMMFKRNSQSVIATIIINIIVLHSLLLISLPFRLSYYLSSVWKLGSFTCRVVSGVIYGHMYLTFVFYVAIVMLRLLIYFKKLQMQQLQKFHAVVLSIIIWIVGSFIFLPIFFLQYGTDPSYTEQQRCFEFHRSLNCTGIIIINYSTIAIMMTTVLVLFLMQLAVILCLIRDYWPDMWAHQDYRAQIKSFFFLIVIVVCFLPHHVFRVYFIQNYPEEKNSKLILYNEICVALTTFCCLDMLCFIGGIIH", "length": 295, "header": "tr|A0A8C2LRC2-1|A0A8C2LRC2_CRIGR Isoform 1 of Probable G-protein coupled receptor 141 OS=Cricetulus griseus OX=10029 GN=LOC100759821 PE=4 SV=1 CANONICAL=A0A8C2LRC2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LRC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRC2/entry#A0A8C2LRC2-1", "sequence": { "sequence": "MDMMNGTTVSNVSSIDQDHCDAYCRTTLITAYSVVLFGGTIGTVMMSRMMFKRNSQSVIATIIINIIVLHSLLLISLPFRLSYYLSSVWKLGSFTCRVVSGVIYGHMYLTFVFYVAIVMLRLLIYFKKLQMQQLQKFHAVVLSIIIWIVGSFIFLPIFFLQYGTDPSYTEQQRCFEFHRSLNCTGIIIINYSTIAIMMTTVLVLFLMQLAVILCLIRDYWPDMWAHQDYRAQIKSFFFLIVIVVCFLPHHVFRVYFIQNYPEEKNSKLILYNEICVALTTFCCLDMLCFIGGIIH", "length": 295, "header": "tr|A0A8C2LRC2-1|A0A8C2LRC2_CRIGR Isoform 1 of Probable G-protein coupled receptor 141 OS=Cricetulus griseus OX=10029 GN=LOC100759821 PE=4 SV=1 CANONICAL=A0A8C2LRC2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"Genome Annotation" ] }, { "id": "IPR000215", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000215", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023796", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023796", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033835", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033835", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042178", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042178", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100764585", "url": 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LRG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRG4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GYF6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GYF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYF6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRAVFSLLLPVLLAEVWLVTSLNFSSHSPKAQAELESWDPQNHTWEENSWTVPGDEEEEDLLKTSQQQLSNETSNFGFSLLRKISMRHDGNVIFSPFGLSVAMVSLMLGAKGETKVQVENGLHLQALSQAGPLILPSLFKRFRETLSSNQELDLAQGSFAFIHKDFDIKETYLNLSKKYFDTECVPTNFRNSSQARGLMNHYINKETRGKIPKLFDEINPETKLILVHYIFFKGKWMTPFDPAFTETDTFHLDKYKAVKVPMMYREGNFASTFDTKFHCHILKLPYQGNATMLVVLMEKTGDHLALEDYLTIDLVETWLQNMKTRKMEVFFPKFKLDQRYEMHQLLQQMGIRRVFSTSADLSELSALARNLQVSKVLQQSVLEVDERGTEAVTGTLSEIVAYSMPPVIKVNRPFHFMIYEEISRMLLFLGRVVNPTVL", "length": 438, "header": "tr|A0A8C2LRG4-1|A0A8C2LRG4_CRIGR Isoform 1 of Protein Z-dependent protease inhibitor isoform X2 OS=Cricetulus griseus OX=10029 GN=Serpina10 PE=3 SV=1 CANONICAL=A0A8C2LRG4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LRG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRG4/entry#A0A8C2LRG4-1", "sequence": { "sequence": "MRAVFSLLLPVLLAEVWLVTSLNFSSHSPKAQAELESWDPQNHTWEENSWTVPGDEEEEDLLKTSQQQLSNETSNFGFSLLRKISMRHDGNVIFSPFGLSVAMVSLMLGAKGETKVQVENGLHLQALSQAGPLILPSLFKRFRETLSSNQELDLAQGSFAFIHKDFDIKETYLNLSKKYFDTECVPTNFRNSSQARGLMNHYINKETRGKIPKLFDEINPETKLILVHYIFFKGKWMTPFDPAFTETDTFHLDKYKAVKVPMMYREGNFASTFDTKFHCHILKLPYQGNATMLVVLMEKTGDHLALEDYLTIDLVETWLQNMKTRKMEVFFPKFKLDQRYEMHQLLQQMGIRRVFSTSADLSELSALARNLQVSKVLQQSVLEVDERGTEAVTGTLSEIVAYSMPPVIKVNRPFHFMIYEEISRMLLFLGRVVNPTVL", "length": 438, "header": "tr|A0A8C2LRG4-1|A0A8C2LRG4_CRIGR Isoform 1 of Protein Z-dependent protease inhibitor isoform X2 OS=Cricetulus griseus OX=10029 GN=Serpina10 PE=3 SV=1 CANONICAL=A0A8C2LRG4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GYF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRG4/entry#A0A9J7GYF6-1", "sequence": { "sequence": "MRAVFSLLLPVLLAEVWLVTSLNFSSHSPKAQAELESWDPQNHTWEENSWTVPGDEEEEDLLKTSQQQLSNETSNFGFSLLRKISMRHDGNVIFSPFGLSVAMVSLMLGAKGETKVQVENGLHLQALSQAGPLILPSLFKRFRETLSSNQELDLAQGSFAFIHKDFDIKETYLNLSKKYFDTECVPTNFRNSSQARGLMNHYINKETRGKIPKLFDEINPETKLILVHYIFFKGNATMLVVLMEKTGDHLALEDYLTIDLVETWLQNMKTRKMEVFFPKFKLDQRYEMHQLLQQMGIRRVFSTSADLSELSALARNLQVSKVLQQSVLEVDERGTEAVTGTLSEIVAYSMPPVIKVNRPFHFMIYEEISRMLLFLGRVVNPTVL", "length": 384, "header": "tr|A0A9J7GYF6-1|A0A9J7GYF6_CRIGR Computationally mapped isoform of Protein Z-dependent protease inhibitor isoform X3 OS=Cricetulus griseus OX=10029 GN=Serpina10 PE=3 SV=1 CANONICAL=A0A8C2LRG4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LRG4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRG4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764585", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764585", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LRG4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRG4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LRG4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRG4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "blood coagulation", "id": "GO:0007596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007596", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LRG4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRG4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 23, "end_pos": 25, "annotation": "n_glycosylation_sequon" }, { "start_pos": 289, "end_pos": 291, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" } ], 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193 }, { "start_pos": 23, "end_pos": 25 }, { "start_pos": 289, "end_pos": 291 }, { "start_pos": 42, "end_pos": 44 }, { "start_pos": 71, "end_pos": 73 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LRG9-1", "uniprot_ac": "A0A8C2LRG9", "uniprot_id": "A0A8C2LRG9_CRIGR", "mass": { "chemical_mass": 57546.0, "monoisotopic_mass": 57546.0 }, "refseq": { "ac": "XP_007653312", "name": "zinc finger protein 623", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007653312" }, "gene_names": [ { "name": "Znf623", "type": "recommended", "evidence": [ { "id": "A0A8C2LRG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRG9" } ] }, { "name": "Znf623", "type": "synonym", "evidence": [ { "id": "XP_007653312", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007653312" } ] } ], "protein_names": [ { "name": "Zinc finger protein 623", "type": "synonym", "evidence": [ { "id": "A0A8C2LRG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRG9/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 623", "type": "synonym", "evidence": [ { "id": "XP_007653312", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007653312" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003617373.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007653312", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007653312" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LRG9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRG9#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LRG9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRG9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Znf623", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRG9", "locus": {} } ], "crossref": [ { "id": "103158562", "url": "https://www.ncbi.nlm.nih.gov/gene/103158562", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:103158562", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103158562", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "THWKIQA", "url": "https://omabrowser.org/oma/group/THWKIQA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LRG9", "url": "https://www.orthodb.org/?gene=A0A8C2LRG9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381:SF435", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381:SF435", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007653312", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007653312", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LRG9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LRG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRG9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMSDKLTVLEPSVSEPGEFQEDRLVQLLGNPERKIIESSPSQEGSLKQMTVTRWKIQTGETAQMCSKSGRNPTLNSNLLILQRELIEGETHSCGIGSKSFSFNSNVVPHQISHTGEKPYQCDRCGKAFSQNSLLTEHQRVHTGDRLYVCNVCGKDFIHYTNLVEHQHVHTDEKPFKCAQCGKAFCHSSDLLRHQRVHTRERPFECKECGKGFSQSSLLIRHQRIHTGERPYECNECGKSFIRSSSLIRHYQIHTEVKQYECRDCGKAFRHRSDLIEHQRIHTGERPFECHECGKAFIRSSKLIQHQRIHTGERPYVCNECGKRFSQTSNFTQHQRIHTGEKLYECDECGKAFFLSSYLIRHQKIHTGERVYECKECGKAFLQKAHLTEHQKIHTGDRPFECKDCGKAFIQSSKLLLHQIVHTGEKPYVCSYCGKGFIQRSNFLQHQKVHTEEKLYKYSQHGKDLTPPPDLVHQEDLSLSETSIHLGERATDQECHADNL", "length": 499, "header": "tr|A0A8C2LRG9-1|A0A8C2LRG9_CRIGR Isoform 1 of Zinc finger protein 623 OS=Cricetulus griseus OX=10029 GN=Znf623 PE=3 SV=1 CANONICAL=A0A8C2LRG9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LRG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRG9/entry#A0A8C2LRG9-1", "sequence": { "sequence": "MMSDKLTVLEPSVSEPGEFQEDRLVQLLGNPERKIIESSPSQEGSLKQMTVTRWKIQTGETAQMCSKSGRNPTLNSNLLILQRELIEGETHSCGIGSKSFSFNSNVVPHQISHTGEKPYQCDRCGKAFSQNSLLTEHQRVHTGDRLYVCNVCGKDFIHYTNLVEHQHVHTDEKPFKCAQCGKAFCHSSDLLRHQRVHTRERPFECKECGKGFSQSSLLIRHQRIHTGERPYECNECGKSFIRSSSLIRHYQIHTEVKQYECRDCGKAFRHRSDLIEHQRIHTGERPFECHECGKAFIRSSKLIQHQRIHTGERPYVCNECGKRFSQTSNFTQHQRIHTGEKLYECDECGKAFFLSSYLIRHQKIHTGERVYECKECGKAFLQKAHLTEHQKIHTGDRPFECKDCGKAFIQSSKLLLHQIVHTGEKPYVCSYCGKGFIQRSNFLQHQKVHTEEKLYKYSQHGKDLTPPPDLVHQEDLSLSETSIHLGERATDQECHADNL", "length": 499, "header": "tr|A0A8C2LRG9-1|A0A8C2LRG9_CRIGR Isoform 1 of Zinc finger protein 623 OS=Cricetulus griseus OX=10029 GN=Znf623 PE=3 SV=1 CANONICAL=A0A8C2LRG9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LRG9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRG9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LRG9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRG9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:103158562", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103158562", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZBN5-1", "protein_name": "Zinc finger protein 623", "gene_name": "Zfp623", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMSDKLTVLEPSVSESREFHEDRLAQLLENPETQSLESPSCQDGGFTQMTVAHWKIQTGDTAPVCSKSGRNPILDSNLLILQRELIEGETRSCGVGGKNFPFNSDVDPHQVSHSGEKSYKCDHCGKGFSQTSLLTEHQRVHTRDRLCVCNVCGKDFIHYANLMEHQLVHTGEKPFKCAQCGKAFCHSSDLLRHQRVHTRERPFECKECGKGFSQSSLLIRHQRIHTGERPYECNECGKSFIRSSSLIRHYQIHTEVKQYECRDCGKAFRHRSDLIEHQRIHTGERPFECHECGKAFIRSSKLIQHQRIHTGERPYVCNECGKRFSQTSNFTQHQRIHTGEKLYECNECGKAFFLSSYLIRHQKIHTGERVYECKECGKAFLQKAHLTEHQKIHTGDRPFECKDCGKAFIQSSKLLLHQIVHTGEKPYVCSYCGKGFIQRSNFLQHQKMHTEEKLYKYSEHGKDLAPPPDLVPQEDLSLSETSVHLGETATDQERCGENF", "length": 499 }, "evidence": [ { "id": "A0A8C2LRG9", "url": "https://omabrowser.org/oma/group/A0A8C2LRG9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3MYK2-1", "protein_name": "Zinc finger protein 623", "gene_name": "ZNF623", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MELTAPTSGRGPDPRLGRLLGNLDAQSLRSCTSQEGGFQQVTVTHWKIQTAEAAQAGSKSEGSPLLSPDLLLLQRELIEGEAPQHEACGSFPFNPGLARHQASHAGEKAHRCDECGKGFSQSSHLVEHQHAHGGERLYVCNACGKDFVLYTDLLEHQKVHTGERPFKCAQCGKAFCHSSDLIRHQRVHTRERPFECKECGKGFSQSSLLIRHQRIHTGERPYECNECGKAFIRSSSLIRHFQVHTEVRQYECQDCGKAFRHRSDLIEHQRIHTGERPFECNECGKAFIRSSKLIQHQRIHTGERPYVCNECGKRFSQTSNFTQHQRIHTGEKLYECNECGKAFFLSSYLIRHQKIHTGERVYECKECGKAFLQKAHLTEHQKIHSGDRPFECKDCGKAFIQSSKLLLHQIIHTGEKPYVCSYCGKGFIQRSNFLQHQKIHTEEKLYECSQYGKEFTPPPDFKSSQEAPQEGLPLSQTAVHFGETCGGLGGHTDF", "length": 494 }, "evidence": [ { "id": "A0A8C2LRG9", "url": "https://omabrowser.org/oma/group/A0A8C2LRG9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O75123-1", "protein_name": "Zinc finger protein 623", "gene_name": "ZNF623", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MILLSFVSDSNVGTGEKKVTEAWISEDENSHRTTSDRLTVMELPSPESEEVHEPRLGELLGNPEGQSLGSSPSQDRGCKQVTVTHWKIQTGETAQVCTKSGRNHILNSDLLLLQRELIEGEANPCDICGKTFTFNSDLVRHRISHAGEKPYTCDQCGKGFGQSSHLMEHQRIHTGERLYVCNVCGKDFIHYSGLIEHQRVHSGEKPFKCAQCGKAFCHSSDLIRHQRVHTRERPFECKECGKGFSQSSLLIRHQRIHTGERPYECNECGKSFIRSSSLIRHYQIHTEVKQYECKECGKAFRHRSDLIEHQRIHTGERPFECNECGKAFIRSSKLIQHQRIHTGERPYVCNECGKRFSQTSNFTQHQRIHTGEKLYECNECGKAFFLSSYLIRHQKIHTGERVYECKECGKAFLQKAHLTEHQKIHSGDRPFECKDCGKAFIQSSKLLLHQIIHTGEKPYVCSYCGKGFIQRSNFLQHQKIHTEEKLYECSQYGRDFNSTTNVKNNQRVHQEGLSLSKAPIHLGERSVDKGEHTGNL", "length": 536 }, "evidence": [ { "id": "A0A8C2LRG9", "url": "https://omabrowser.org/oma/group/A0A8C2LRG9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LRG9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRG9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LRG9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRG9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LRG9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRG9" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LRG9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRG9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LRG9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRG9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LRG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRG9" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 91, "end_pos": 118, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 329, "end_pos": 331 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LRL5-1", "uniprot_ac": "A0A8C2LRL5", "uniprot_id": "A0A8C2LRL5_CRIGR", "mass": { "chemical_mass": 105664.0, "monoisotopic_mass": 105664.0 }, "refseq": { "ac": "XP_007644486", "name": "DENN domain-containing protein 2C isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644486" }, "gene_names": [ { "name": "Dennd2c", "type": "recommended", "evidence": [ { "id": "A0A8C2LRL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRL5" } ] }, { "name": "Dennd2c", "type": "synonym", "evidence": [ { "id": "XP_007644486", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644486" } ] } ], "protein_names": [ { "name": "DENN domain-containing protein 2C isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007644486", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644486" }, { "id": "A0A8C2LRL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRL5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614192.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007644486", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644486" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LRL5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRL5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Dennd2c", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRL5", "locus": {} } ], "crossref": [ { "id": "100758192", "url": "https://www.ncbi.nlm.nih.gov/gene/100758192", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001194", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001194", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758192", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758192", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PDSKDWI", "url": "https://omabrowser.org/oma/group/PDSKDWI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LRL5", "url": "https://www.orthodb.org/?gene=A0A8C2LRL5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15288", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15288", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15288:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15288:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02141", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02141", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03455", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03455", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03456", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03456", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007644486", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644486", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LRL5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LRL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRL5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F2S6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2S6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F2S6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F2S6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHPTGNMDVGFTRSAVQTLSRSHCKNIKQKISQWEGRANGVTKPARFHPKDFGVSYNNCHQEAPPQKCPSGDEKSNYQNGDLPWSTDAKSHDQSDHEGEQRECKDAHPAETGPDSNWVCARVKQIESLRDVTVDPEASLPPGNVYTSQILWKRIEALPPDKVLNLALAPCDSTEKVPNFRVLDSSYGITKSLENIYCEPEGQECGSSINPLPKPRRTFRYLSESGSVPCKERNCDQKYCEKNSCVESSLASSQDPEPKKYGGKIRGRSKRKSFEFEDIQHFRNSRKIHEELGRNAGSALYYTQSEDNIYEDIIYPAKENPYEDIPVQPFPIWRSPSAWRLPPAKMAFRAPKLPPKPQFLQRKTMELKNSQAYLRSKLTKDTTLPVTLTEWKLFRAGEVANRKKRNLPRLVLKINDTFESKRGKKRVKLQPYTGKEAPSSKGETSGNESDGEYLPKNRHKRLAQLLQPSKRNPHYQTLERDLIELQEQQLFELFVVVSLQKKPSGTNYVPQVIQQFPSKGDNGYKQSKDTEERLKVIPRFCFPDSKDWVPTSEFKSETFSFVLTGEDGSRWFGYCKKLLPEGKGKRFPEVYCMVSRLGCFNLFSKILDEVEKRREMSPALVYPFMRSVMEAPFPAPGRTITVKSYLPGAGDGAVELCRPLDSRLEHVDFECLFKCLSVCHLIRVCASLLLERRVIFVANSLSTLSKCGHAVVATLYPFTWQHTYIPVLPASMIDIVCSPTPFLIGILSCSLPQLQDLPIEEVLIVDLCADKFLQEVSDEGEILPPKLQAALVQILEDRTEVLAQEQQFSQDVTLNSLVSEAFVRFFVELVGHYSLNMTVTERGERVFQREPFRKSHTSRSVRHFLDLFMETQMFAGFVQDRELRQSGVKGLFEVRALQYLETIPESEPSGVNRILRSLGSKMRFLHKK", "length": 927, "header": "tr|A0A8C2LRL5-1|A0A8C2LRL5_CRIGR Isoform 1 of DENN domain-containing protein 2C isoform X1 OS=Cricetulus griseus OX=10029 GN=Dennd2c PE=4 SV=1 CANONICAL=A0A8C2LRL5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LRL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRL5/entry#A0A8C2LRL5-1", "sequence": { "sequence": "MHPTGNMDVGFTRSAVQTLSRSHCKNIKQKISQWEGRANGVTKPARFHPKDFGVSYNNCHQEAPPQKCPSGDEKSNYQNGDLPWSTDAKSHDQSDHEGEQRECKDAHPAETGPDSNWVCARVKQIESLRDVTVDPEASLPPGNVYTSQILWKRIEALPPDKVLNLALAPCDSTEKVPNFRVLDSSYGITKSLENIYCEPEGQECGSSINPLPKPRRTFRYLSESGSVPCKERNCDQKYCEKNSCVESSLASSQDPEPKKYGGKIRGRSKRKSFEFEDIQHFRNSRKIHEELGRNAGSALYYTQSEDNIYEDIIYPAKENPYEDIPVQPFPIWRSPSAWRLPPAKMAFRAPKLPPKPQFLQRKTMELKNSQAYLRSKLTKDTTLPVTLTEWKLFRAGEVANRKKRNLPRLVLKINDTFESKRGKKRVKLQPYTGKEAPSSKGETSGNESDGEYLPKNRHKRLAQLLQPSKRNPHYQTLERDLIELQEQQLFELFVVVSLQKKPSGTNYVPQVIQQFPSKGDNGYKQSKDTEERLKVIPRFCFPDSKDWVPTSEFKSETFSFVLTGEDGSRWFGYCKKLLPEGKGKRFPEVYCMVSRLGCFNLFSKILDEVEKRREMSPALVYPFMRSVMEAPFPAPGRTITVKSYLPGAGDGAVELCRPLDSRLEHVDFECLFKCLSVCHLIRVCASLLLERRVIFVANSLSTLSKCGHAVVATLYPFTWQHTYIPVLPASMIDIVCSPTPFLIGILSCSLPQLQDLPIEEVLIVDLCADKFLQEVSDEGEILPPKLQAALVQILEDRTEVLAQEQQFSQDVTLNSLVSEAFVRFFVELVGHYSLNMTVTERGERVFQREPFRKSHTSRSVRHFLDLFMETQMFAGFVQDRELRQSGVKGLFEVRALQYLETIPESEPSGVNRILRSLGSKMRFLHKK", "length": 927, "header": "tr|A0A8C2LRL5-1|A0A8C2LRL5_CRIGR Isoform 1 of DENN domain-containing protein 2C isoform X1 OS=Cricetulus griseus OX=10029 GN=Dennd2c PE=4 SV=1 CANONICAL=A0A8C2LRL5-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F2S6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRL5/entry#A0A9J7F2S6-1", "sequence": { "sequence": "MASTCQRVNRHKRLAQLLQPSKRNPHYQTLERDLIELQEQQLFELFVVVSLQKKPSGTNYVPQVIQQFPSKGDNGYKQSKDTEERLKVIPRFCFPDSKDWVPTSEFKSETFSFVLTGEDGSRWFGYCKKLLPEGKGKRFPEVYCMVSRLGCFNLFSKILDEVEKRREMSPALVYPFMRSVMEAPFPAPGRTITVKSYLPGAGDGAVELCRPLDSRLEHVDFECLFKCLSVCHLIRVCASLLLERRVIFVANSLSTLSKCGHAVVATLYPFTWQHTYIPVLPASMIDIVCSPTPFLIGILSCSLPQLQDLPIEEVLIVDLCADKFLQEVSDEGEILPPKLQAALVQILEDRTEVLAQEQQFSQDVTLNSLVSEAFVRFFVELVGHYSLNMTVTERGERVFQREPFRKSHTSRSVRHFLDLFMETQMFAGFVQDRELRQSGVKGLFEVRALQYLETIPESEPSGVNRILRSLGSKMRFLHKK", "length": 480, "header": "tr|A0A9J7F2S6-1|A0A9J7F2S6_CRIGR Computationally mapped isoform of DENN domain-containing protein 2C isoform X2 OS=Cricetulus griseus OX=10029 GN=Dennd2c PE=4 SV=1 CANONICAL=A0A8C2LRL5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LRL5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRL5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LRL5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRL5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758192", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758192", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q68D51-1", "protein_name": "DENN domain-containing protein 2C", "gene_name": "DENND2C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVGFSRTTVQTLSRSHCKNIKQKISQWEGRANGISNPEKWCPKDFGVRYNCHQEIRLKKNPIAERKSKNLDVTSRENVGLDINENTKSHDQSENENKKHEYDDTHFFKNESESNWVCSRVKEIESCKEDVLDPETSLPPGNFYTSQILWKKIEALPPDKLLNLALEHCDSSEKELNFRVLDSSYGITKSLENIYSEPEGQECGPSINPLPKPRRTFRYLSESGVTPYKERNCDKKYCENNSCAQSSLASSQEPEPKKYGGKIRGRSKRKSFEFEDIQHFRNRNSQTIREELGRNSGSALYYTQSEDNIYEDIIYPTKENPYEDIPVQPLPMWRSPSAWKLPPAKSAFKAPKLPPKPQFLHRKTMEVKNSQAYLRSKLTKDTTLPVTLTEWKLFRAGEVANTKRKNLPRLVLKIDDIFESKRGKKKVKLHSYTGKELPPTKGETSGNESDAEYLPKNRHKRLAQLQPSSKRNPHYQTLERDLIELQEQQLFELFVVVSLQKKPSGISYIPQVIQQFPGKDDHGYKQSKDMEERLKVIPKFCFPDSKDWMPTSELKSETFSFVLTGEDGSRWFGYCKKLLPVGKGKRLPEVYCMVSRLGCFNLFSKILDEVEKRREMSPALVYPFMRSVMEAPFPAPGRTITVKSYLPGAGDESIELCRPLDSRLEHVDFKCLFKCLSVCHLIRVCASLLLERRVIFVANSLSTLSKCGHAVVATLYPFTWQHTYIPVLPASMIDIVCSPTPFLIGILSCSLPQLQDLPIEEVLIVDLCADKFLQEVSDEDEILPPKLQAALMQILEERNEILTQEQNFSQDVTLNSLVSEAFVRFFVELVGHYSLNMTVTERGERVFQREPFRKSHTSRSVRHFLDLFMETQMFAGFIQDRELRKSGVKGLFEIRAIQYLETIPESEPSGMNRILRSLGSKMKFLQKK", "length": 928 }, "evidence": [ { "id": "A0A8C2LRL5", "url": "https://omabrowser.org/oma/group/A0A8C2LRL5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P9P8-1", "protein_name": "DENN domain-containing protein 2C", "gene_name": "Dennd2c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDVGFTRSAVQTLSRSHCKNIKQKISQWEGRANGVTKTAKFHPKDFGVRYNCHQESPPHKRPTGEERNGALPRNTDVKSRDQSEDEGEGGECRGSHPSEAGLDSSLVCARVKQIEGCQAVAVGPEASLPPGNFYTSQIPWRSIDGLSPDKPLNLALAPCNSTGREPDLSVLDSSYGITKSLENIYYEPEGQECGPSINPLPKPRRTFRYLSESDGIPYKERNCDQKYCESISCVDPSLASSQDPEPKKYGGKIRGRSKRKSFEFEDIQHFRNSRKIHEELGRNAGSALYYTQSEDNIYEDIIYPAKENPYEDIPVQSFPVWRSPSAWRLPPAKSAFRTPKLPPKPQFFQRKTMELKNSQAYFRSKITKDTTLPVTLTEWKLFRAGEVANKKKRNLPPLVLKINDTFESKRGKKRVKLQPYTGKEAPSSKGETSGNESDAEYLPKNRHKRLAQLQPSSKRNPHYQTLERDLIELQEQQLFELFVVVSLQKKPAGYTPQVIQQFPSKGDHGYKQSKDTEERLKVIPRFCFPDSEDSAPTLELKSETFSFVLTGEDGSRWFGYCKKLLPEGRGKRLPEVYCMVSRLGCFNLFSKILDEVEKRREMSPALVYPFMRSVMEAPFPAPGRTITVKSYLPGAGDESIELCRPLDSRLEHVDFECLFKCLSVRHLIRVCASLLLERRVIFVANSLSTLSKCGHAVVATLYPFTWQHTYIPVLPVSMIDIVCSPTPFFIGILSCSLPHLQDLPIEEVLIVDLCADRFLQEVSDEDEILPPKLQAALVQILEDRDEVLAQEQQFSQEVTLSSLVSEAFVRFFVELVGHYSLNMTVTERGERVFQREPFRKSHTSRSVRHFLDLFMETQMFAGFVQDRELRQSGVKGLFEVRALQYLETIPESEPSGVNRILRSLGSKMKFLHKK", "length": 914 }, "evidence": [ { "id": "A0A8C2LRL5", "url": "https://omabrowser.org/oma/group/A0A8C2LRL5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LRL5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRL5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LRL5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRL5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 414, "end_pos": 416, "annotation": "n_glycosylation_sequon" }, { "start_pos": 446, "end_pos": 448, "annotation": "n_glycosylation_sequon" }, { "start_pos": 835, "end_pos": 837, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LRL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRL5" }, { "id": "PS50211", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50211" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UDENN", "eco_id": "ECO_0000259", "start_pos": 491, "end_pos": 887, "start_aa": "Glu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 414, "end_pos": 416 }, { "start_pos": 446, "end_pos": 448 }, { "start_pos": 835, "end_pos": 837 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LRL6-1", "uniprot_ac": "A0A8C2LRL6", "uniprot_id": "A0A8C2LRL6_CRIGR", "mass": { "chemical_mass": 63358.0, "monoisotopic_mass": 63358.0 }, "refseq": { "ac": "XP_027284522", "name": "EF-hand and coiled-coil domain-containing protein 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284522" }, "gene_names": [ { "name": "Efcc1", "type": "recommended", "evidence": [ { "id": "A0A8C2LRL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRL6" } ] }, { "name": "Efcc1", "type": "synonym", "evidence": [ { "id": "XP_027284522", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284522" } ] } ], "protein_names": [ { "name": "EF-hand and coiled-coil domain-containing protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027284522", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027284522" }, { "id": "A0A8C2LRL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRL6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. 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"annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LRW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LRW8" }, { "id": "PF10506", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10506" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Harmonin-binding protein USHBP1 PDZ-binding", "eco_id": "ECO_0000259", "start_pos": 281, "end_pos": 344, "start_aa": "Gln", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 225, "end_pos": 227 }, { "start_pos": 35, "end_pos": 37 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LS26-1", "uniprot_ac": "A0A8C2LS26", "uniprot_id": "A0A8C2LS26_CRIGR", "mass": { "chemical_mass": 281382.0, "monoisotopic_mass": 281382.0 }, "refseq": { "ac": "XP_027281227", "name": "BAH and coiled-coil domain-containing protein 1 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281227" }, "gene_names": [ { "name": "Bahcc1", "type": "recommended", "evidence": [ { "id": "A0A8C2LS26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS26" } ] }, { "name": "Bahcc1", "type": "synonym", "evidence": [ { "id": "XP_027281227", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281227" } ] } ], "protein_names": [ { "name": "BAH and coiled-coil domain-containing protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027281227", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281227" }, { "id": "A0A8C2LS26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS26/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027281227", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281227" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LS26", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS26" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Bahcc1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS26", "locus": {} } ], "crossref": [ { "id": "cd04714", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04714", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20470", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20470", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100754288", "url": "https://www.ncbi.nlm.nih.gov/gene/100754288", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001025", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001025", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047411", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047411", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048924", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048924", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052429", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052429", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754288", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754288", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LS26", "url": "https://www.orthodb.org/?gene=A0A8C2LS26", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12505", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12505", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12505:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12505:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01426", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01426", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21744", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21744", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027281227", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281227", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LS26", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS26", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LS26-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS26-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAQ8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GAQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GAQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GBH1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GBH1", "database": 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"MDGRDFAPPPHLLSERGSLGHRSAAAAARLAPAGPAAQPAAHFQPGKYFPSPLPMASHTASSRLMGNPPASSFMGSFLTSSLGSAASAHPSGPSSSPSEPAYRGSHPATSQIWFSHSHEAPAYPRFSGSLASTFLPVSHLDHHGNSNVLYGQHRFYGTQKDNFYLRNLPPQPTILPANHNFPGVPRATPAHTIGSCSRDRIEAAPLQKGPKEFDRFLMGKELGKEKASKVAEGRERPAAEEDSSKDRQKLVPPMPTEGPCKEGGPTPRGSCEGRPKHLTSCLLNAKVLNGDMGKASLASCAGGVLGRPSTGAGAPGRCAQEVAGPVEPGAAFSECLERRQMLHHAVSYTVPSGLPTGPPPPLSTGPAGSFPCLQLHAGPDGLCPLQDKVSRDLKASGPTFVPSVGHLADKSRPFQVAEACAVAGDGKDRHLDGTMAPDHGAPYGVSYAHLKAEGKGERRPGGFEAALHPRLKGLEYLSAGPEAPFPGLPKGGLDKSGYFELPTPSQDCARPNHQDSLSGKATQACCTLDKMASKEAPAGPPGAQKVARIRHQQHLVAPEVESGGSGVDAKRKSVELASLGYSGPHMPPWGVQTGHSTSMAISEERKGSAYLDPFGSGLQQAALLSQELPTPPDEVSAMKNLLKYSNQALVVGQKAPFVGLGGLKASCVQQEAKFPATKGPGPVERPDCARSREHEAPHGDGEVRQPPVGIAVALARQKDTVSRPDAAYSTNSGRQGRAAPTFKAAGGSRATHALDLESEEERTRMCDDRLGLPGRELLLQDNKDLVEFARIHPSSSCPGDLPPHLMMQGGQLGGDPAPHPHPAHPHWLPRTRSPSLWMGGHSYGLGHPALHQSLPPGFPASVPGSMPSVFPLPQDAATQLVILPSEPTPHTNTLADVMDQASLWPPMYGARGPTSHMQHPGQLPVYSRSQLLRQQELYALQQQQQQQQQQQQQQQQQQQQQQQQRATQALELQRAAQFQRKPEDRHLELEEPAQEKAPKSTHKPVALTPMAKGTPPSATAGLVKLSPCCHSPNLKTPAGCPTPPAHPSAPCTLTVGPTGSPGPGSKVPSTKDKSGEGQRAGTDLTTLEPGLPPGLNPTAGMDFSLPADVHSSDPPDPKTMQTTTPGTQPEPTRTFLPGEPPPCSPRSLEEPGLLSRAREATQDLAIIPHPVERGLPPGKAEDPSPLEGLQALRFGDLLEGGGTEATGQTNSTQGGMQSERTMDQGVPQPPLGATPQALEQITGSPGALDKDDGSQKVPDTAQLQVEEAHLEENEGDSEVDWETPNHSHPPKVLPGLDALVAATVDLGDLPDINLPDPQTQAASVPVSTAPLPHTSGIHGIALLSELADLEIQRQKSELAMQAEDEDVLAFNLQHLATLATAWSLVEAASLDSSVPSLQAPATDPDRGPRVTPRMQILQRKDTWAPKTKPVCPLKAAIDRLDTQEVEMRMQLAELQRRYKDKQRELARLQRRHDHEREESSRSPARRGPGRPRKRKHSSSLPTLRPGGQLTRSDGKKAKAVRASLSLLCAELRGDEPTRKRSKLEKSAYTGLQTASSEKVRCKKSGGQAELSSSVAHKVAQLKPRVKSKGLPTGLGAFQRKEAAPGGRIRKKLSRARSVKVSGATQHPHPDGDGGRGMPKFPAQPAVAVPREAGSGYDSEDCQALLGTEAASREPGLVLHPGAGMAVLGPSPSSVVKMEANQKAKKKKERQGLLGACRLSSPEGEVKIKRRTVKSKVGPKLERAPGRRPPGAPGKKKAKGKAKSGLCAEPGAATNRDALFSPTRTFACREEGSKLASERLKRATRKSAMLQPVLRRKNGALSIALSARNAKAVLGKSRKLTKVKRETVSKQGQGRAVSRLLESFAVEDDFEFDDDSSFSDEEEEEEEASVQLSAEQSAALARSCTIHKEDLQDGLPVLIPKEDSLLYAGSVRTLQPPDIYSIVIEGERGNRPRIYSLEQLLQEAVLDVRPQSSRYLPPGTRVCAYWSQKSRCLYPGNVVRGASSDEEEDLDSVVVEFDDGDTGHIAVSNIRLLPPDFKIQCTEPSPALLVSSSCRRTKKTSSEAPQPSEAPSPSLSPKVQDGPEPSKTPGKKSISKDKAGKVDLLTSGAKSPMGASDHFLGRRGSPLLSWSAVAQTKRKAAAAAAGGKGPGMLQNLFQLNGSTKKLRARETLFPMHSMAAPVFGNSFRADSFSSLASSYTPFVGGAGAGLPGGAHKLLRAKKVERAEAEKASRRRPGGEFLVKLDHEGVTSPKNKNCKALLMGDKDFGPKLGRPLASPSYAHPALMGKDKKGRTPVHPLPMGLALRKYPLPCDSDCPSSCSDEDEDGPGLATGVPSRFLTRLSMSSSSSGSSTSSSSGSMSTSSLCSSDNEDSSYSSDDEDPALLLQTCLTRPVPALLAPPEALRSKGSSPHTHAQRCFLSRAGVAGAGAGAGPGPSGGKSKFKRKEALSFSKAKELSRRQRLPSVENRPKISAFLPARQLWKWSGNPTQRRGMKGKARKLFYKAIVRGKETLRIGDCAVFLSAGRPNLPYIGRIESLWESWGSNMVVKVKWFYHPEETKLGKRQSDGKNALYQSCHEDENDVQTISHKCQVVGREQYERMMRGRNYQDQQDLYYLAGTYDPTTGRLVTADGVPILC", "length": 2636, "header": "tr|A0A8C2LS26-1|A0A8C2LS26_CRIGR Isoform 1 of BAH and coiled-coil domain-containing protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Bahcc1 PE=4 SV=1 CANONICAL=A0A8C2LS26-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LS26-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS26/entry#A0A8C2LS26-1", "sequence": { "sequence": "MDGRDFAPPPHLLSERGSLGHRSAAAAARLAPAGPAAQPAAHFQPGKYFPSPLPMASHTASSRLMGNPPASSFMGSFLTSSLGSAASAHPSGPSSSPSEPAYRGSHPATSQIWFSHSHEAPAYPRFSGSLASTFLPVSHLDHHGNSNVLYGQHRFYGTQKDNFYLRNLPPQPTILPANHNFPGVPRATPAHTIGSCSRDRIEAAPLQKGPKEFDRFLMGKELGKEKASKVAEGRERPAAEEDSSKDRQKLVPPMPTEGPCKEGGPTPRGSCEGRPKHLTSCLLNAKVLNGDMGKASLASCAGGVLGRPSTGAGAPGRCAQEVAGPVEPGAAFSECLERRQMLHHAVSYTVPSGLPTGPPPPLSTGPAGSFPCLQLHAGPDGLCPLQDKVSRDLKASGPTFVPSVGHLADKSRPFQVAEACAVAGDGKDRHLDGTMAPDHGAPYGVSYAHLKAEGKGERRPGGFEAALHPRLKGLEYLSAGPEAPFPGLPKGGLDKSGYFELPTPSQDCARPNHQDSLSGKATQACCTLDKMASKEAPAGPPGAQKVARIRHQQHLVAPEVESGGSGVDAKRKSVELASLGYSGPHMPPWGVQTGHSTSMAISEERKGSAYLDPFGSGLQQAALLSQELPTPPDEVSAMKNLLKYSNQALVVGQKAPFVGLGGLKASCVQQEAKFPATKGPGPVERPDCARSREHEAPHGDGEVRQPPVGIAVALARQKDTVSRPDAAYSTNSGRQGRAAPTFKAAGGSRATHALDLESEEERTRMCDDRLGLPGRELLLQDNKDLVEFARIHPSSSCPGDLPPHLMMQGGQLGGDPAPHPHPAHPHWLPRTRSPSLWMGGHSYGLGHPALHQSLPPGFPASVPGSMPSVFPLPQDAATQLVILPSEPTPHTNTLADVMDQASLWPPMYGARGPTSHMQHPGQLPVYSRSQLLRQQELYALQQQQQQQQQQQQQQQQQQQQQQQQRATQALELQRAAQFQRKPEDRHLELEEPAQEKAPKSTHKPVALTPMAKGTPPSATAGLVKLSPCCHSPNLKTPAGCPTPPAHPSAPCTLTVGPTGSPGPGSKVPSTKDKSGEGQRAGTDLTTLEPGLPPGLNPTAGMDFSLPADVHSSDPPDPKTMQTTTPGTQPEPTRTFLPGEPPPCSPRSLEEPGLLSRAREATQDLAIIPHPVERGLPPGKAEDPSPLEGLQALRFGDLLEGGGTEATGQTNSTQGGMQSERTMDQGVPQPPLGATPQALEQITGSPGALDKDDGSQKVPDTAQLQVEEAHLEENEGDSEVDWETPNHSHPPKVLPGLDALVAATVDLGDLPDINLPDPQTQAASVPVSTAPLPHTSGIHGIALLSELADLEIQRQKSELAMQAEDEDVLAFNLQHLATLATAWSLVEAASLDSSVPSLQAPATDPDRGPRVTPRMQILQRKDTWAPKTKPVCPLKAAIDRLDTQEVEMRMQLAELQRRYKDKQRELARLQRRHDHEREESSRSPARRGPGRPRKRKHSSSLPTLRPGGQLTRSDGKKAKAVRASLSLLCAELRGDEPTRKRSKLEKSAYTGLQTASSEKVRCKKSGGQAELSSSVAHKVAQLKPRVKSKGLPTGLGAFQRKEAAPGGRIRKKLSRARSVKVSGATQHPHPDGDGGRGMPKFPAQPAVAVPREAGSGYDSEDCQALLGTEAASREPGLVLHPGAGMAVLGPSPSSVVKMEANQKAKKKKERQGLLGACRLSSPEGEVKIKRRTVKSKVGPKLERAPGRRPPGAPGKKKAKGKAKSGLCAEPGAATNRDALFSPTRTFACREEGSKLASERLKRATRKSAMLQPVLRRKNGALSIALSARNAKAVLGKSRKLTKVKRETVSKQGQGRAVSRLLESFAVEDDFEFDDDSSFSDEEEEEEEASVQLSAEQSAALARSCTIHKEDLQDGLPVLIPKEDSLLYAGSVRTLQPPDIYSIVIEGERGNRPRIYSLEQLLQEAVLDVRPQSSRYLPPGTRVCAYWSQKSRCLYPGNVVRGASSDEEEDLDSVVVEFDDGDTGHIAVSNIRLLPPDFKIQCTEPSPALLVSSSCRRTKKTSSEAPQPSEAPSPSLSPKVQDGPEPSKTPGKKSISKDKAGKVDLLTSGAKSPMGASDHFLGRRGSPLLSWSAVAQTKRKAAAAAAGGKGPGMLQNLFQLNGSTKKLRARETLFPMHSMAAPVFGNSFRADSFSSLASSYTPFVGGAGAGLPGGAHKLLRAKKVERAEAEKASRRRPGGEFLVKLDHEGVTSPKNKNCKALLMGDKDFGPKLGRPLASPSYAHPALMGKDKKGRTPVHPLPMGLALRKYPLPCDSDCPSSCSDEDEDGPGLATGVPSRFLTRLSMSSSSSGSSTSSSSGSMSTSSLCSSDNEDSSYSSDDEDPALLLQTCLTRPVPALLAPPEALRSKGSSPHTHAQRCFLSRAGVAGAGAGAGPGPSGGKSKFKRKEALSFSKAKELSRRQRLPSVENRPKISAFLPARQLWKWSGNPTQRRGMKGKARKLFYKAIVRGKETLRIGDCAVFLSAGRPNLPYIGRIESLWESWGSNMVVKVKWFYHPEETKLGKRQSDGKNALYQSCHEDENDVQTISHKCQVVGREQYERMMRGRNYQDQQDLYYLAGTYDPTTGRLVTADGVPILC", "length": 2636, "header": "tr|A0A8C2LS26-1|A0A8C2LS26_CRIGR Isoform 1 of BAH and coiled-coil domain-containing protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Bahcc1 PE=4 SV=1 CANONICAL=A0A8C2LS26-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GAQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS26/entry#A0A9J7GAQ8-1", "sequence": { "sequence": "MGNPPASSFMGSFLTSSLGSAASAHPSGPSSSPSEPAYRGSHPATSQIWFSHSHEAPAYPRFSGSLASTFLPVSHLDHHGNSNVLYGQHRFYGTQKDNFYLRNLPPQPTILPANHNFPGVPRATPAHTIGSCSRDRIEAAPLQKGPKEFDRFLMGKELGKEKASKVAEGRERPAAEEDSSKDRQKLVPPMPTEGPCKEGGPTPRGSCEGRPKHLTSCLLNAKVLNGDMGKASLASCAGGVLGRPSTGAGAPGRCAQEVAGPVEPGAAFSECLERRQMLHHAVSYTVPSGLPTGPPPPLSTGPAGSFPCLQLHAGPDGLCPLQDKVSRDLKASGPTFVPSVGHLADKSRPFQVAEACAVAGDGKDRHLDGTMAPDHGAPYGVSYAHLKAEGKGERRPGGFEAALHPRLKGLEYLSAGPEAPFPGLPKGGLDKSGYFELPTPSQDCARPNHQDSLSGKATQACCTLDKMASKEAPAGPPGAQKVARIRHQQHLVAPEVESGGSGVDAKRKSVELASLGYSGPHMPPWGVQTGHSTSMAISEERKGSAYLDPFGSGLQQAALLSQELPTPPDEVSAMKNLLKYSNQALVVGQKAPFVGLGGLKASCVQQEAKFPATKGPGPVERPDCARSREHEAPHGDGEVRQPPVGIAVALARQKDTVSRPDAAYSTNSGRQGRAAPTFKAAGGSRATHALDLESEEERTRMCDDRLGLPGRELLLQDNKDLVEFARIHPSSSCPGDLPPHLMMQGGQLGGDPAPHPHPAHPHWLPRTRSPSLWMGGHSYGLGHPALHQSLPPGFPASVPGSMPSVFPLPQDAATQLVILPSEPTPHTNTLADVMDQASLWPPMYGARGPTSHMQHPGQLPVYSRSQLLRQQELYALQQQQQQQQQQQQQQQQQQQQQQQQRATQALELQRAAQFQRKPEDRHLELEEPAQEKAPKSTHKPVALTPMAKGTPPSATAGLVKLSPCCHSPNLKTPAGCPTPPAHPSAPCTLTVGPTGSPGPGSKVPSTKDKSGEGQRAGTDLTTLEPGLPPGLNPTAGMDFSLPADVHSSDPPDPKTMQTTTPGTQPEPTRTFLPGEPPPCSPRSLEEPGLLSRAREATQDLAIIPHPVERGLPPGKAEDPSPLEGLQALRFGDLLEGGGTEATGQTNSTQGGMQSERTMDQGVPQPPLGATPQALEQITGSPGALDKDDGSQKVPDTAQLQVEEAHLEENEGDSEVDWETPNHSHPPKVLPGLDALVAATVDLGDLPDINLPDPQTQAASVPVSTAPLPHTSGIHGIALLSELADLEIQRQKSELAMQAEDEDVLAFNLQHLATLATAWSLVEAASLDSSVPSLQAPATDPDRGPRVTPRMQILQRKDTWAPKTKPVCPLKAAIDRLDTQEVEMRMQLAELQRRYKDKQRELARLQRRHDHEREESSRSPARRGPGRPRKRKHSSSLPTLRPGGQLTRSDGKKAKAVRASLSLLCAELRGDEPTRKRSKLEKSAYTGLQTASSEKVRCKKSGGQAELSSSVAHKVAQLKPRVKSKGLPTGLGAFQRKEAAPGGRIRKKLSRARSVKVSGATQHPHPDGDGGRGMPKFPAQPAVAVPREAGSGYDSEDCQALLGTEAASREPGLVLHPGAGMAVLGPSPSSVVKMEANQKAKKKKERQGLLGACRLSSPEGEVKIKRRTVKSKVGPKLERAPGRRPPGAPGKKKAKGKAKSGLCAEPGAATNRDALFSPTRTFACREEGSKLASERLKRATRKSAMLQPVLRRKNGALSIALSARNAKAVLGKSRKLTKVKRETVSKQGQGRAVSRLLESFAVEDDFEFDDDSSFSDEEEEEEEASVQLSAEQSAALARSCTIHKEDLQDGLPVLIPKEDSLLYAGSVRTLQPPDIYSIVIEGERGNRPRIYSLEQLLQEAVLDVRPQSSRYLPPGTRVCAYWSQKSRCLYPGNVVRGASSDEEEDLDSVVVEFDDGDTGHIAVSNIRLLPPDFKIQCTEPSPALLVSSSCRRTKKTSSEAPQPSEAPSPSLSPKVQDGPEPSKTPGKKSISKDKAGKVDLLTSGAKSPMGASDHFLGRRGSPLLSWSAVAQTKRKAAAAAAGGKGPGMLQNLFQLNGSTKKLRARETLFPMHSMAAPVFGNSFRADSFSSLASSYTPFVGGAGAGLPGGAHKLLRAKKVERAEAEKASRRRPGGEFLVKLDHEGVTSPKNKNCKALLMGDKDFGPKLGRPLASPSYAHPALMGKDKKGRTPVHPLPMGLALRKYPLPCDSDCPSSCSDEDEDGPGLATGVPSRFLTRLSMSSSSSGSSTSSSSGSMSTSSLCSSDNEDSSYSSDDEDPALLLQTCLTRPVPALLAPPEALRSKGSSPHTHAQRCFLSRAGVAGAGAGAGPGPSGGKSKFKRKEALSFSKAKELSRRQRLPSVENRPKISAFLPARQLWKWSGNPTQRRGMKGKARKLFYKAIVRGKETLRIGDCAVFLSAGRPNLPYIGRIESLWESWGSNMVVKVKWFYHPEETKLGKRQSDGKNALYQSCHEDENDVQTISHKCQVVGREQYERMMRGRNYQDQQDLYYLAGTYDPTTGRLVTADGVPILC", "length": 2572, "header": "tr|A0A9J7GAQ8-1|A0A9J7GAQ8_CRIGR Computationally mapped isoform of BAH and coiled-coil domain-containing protein 1 isoform X5 OS=Cricetulus griseus OX=10029 GN=Bahcc1 PE=4 SV=1 CANONICAL=A0A8C2LS26-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GBH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS26/entry#A0A9J7GBH1-1", "sequence": { "sequence": "MDGRDFAPPPHLLSERGSLGHRSAAAAARLAPAGPAAQPAAHFQPGKYFPSPLPMASHTASSRLMGNPPASSFMGSFLTSSLGSAASAHPSGPSSSPSEPAYRGSHPATSQIWFSHSHEAPAYPRFSGSLASTFLPVSHLDHHGNSNVLYGQHRFYGTQKDNFYLRNLPPQPTILPANHNFPGVPRATPAHTIGSCSRDRIEAAPLQKGPKEFDRFLMGKELGKEKASKVAEGRERPAAEEDSSKDRQKLVPPMPTEGPCKEGGPTPRGSCEGRPKHLTSCLLNAKVLNGDMGKASLASCAGGVLGRPSTGAGAPGRCAQEVAGPVEPGAAFSECLERRQMLHHAVSYTVPSGLPTGPPPPLSTGPAGSFPCLQLHAGPDGLCPLQDKVSRDLKASGPTFVPSVGHLADKSRPFQVAEACAVAGDGKDRHLDGTMAPDHGAPYGVSYAHLKAEGKGERRPGGFEAALHPRLKGLEYLSAGPEAPFPGLPKGGLDKSGYFELPTPSQDCARPNHQDSLSGKATQACCTLDKMASKEAPAGPPGAQKVARIRHQQHLVAPEVESGGSGVDAKRKSVELASLGYSGPHMPPWGVQTGHSTSMAISEERKGSAYLDPFGSGLQQAALLSQELPTPPDEVSAMKNLLKYSNQALVVGQKAPFVGLGGLKASCVQQEAKFPATKGPGPVERPDCARSREHEAPHGDGEVRQPPVGIAVALARQKDTVSRPDAAYSTNSGRQGRAAPTFKAAGGSRATHALDLESEEERTRMCDDRLGLPGRELLLQDNKDLVEFARIHPSSSCPGDLPPHLMMQGGQLGGDPAPHPHPAHPHWLPRTRSPSLWMGGHSYGLGHPALHQSLPPGFPASVPGSMPSVFPLPQDAATQLVILPSEPTPHTNTLADVMDQASLWPPMYGARGPTSHMQHPGQLPVYSRSQLLRQQELYALQQQQQQQQQQQQQQQQQQQQQQQQRATQALELQRAAQFQRKPEDRHLELEEPAQEKAPKSTHKPVALTPMAKGTPPSATAGLVKLSPCCHSPNLKTPAGCPTPPAHPSAPCTLTVGPTGSPGPGSKVPSTKDKSGEGQRAGTDLTTLEPGLPPGLNPTAGMDFSLPADVHSSDPPDPKTMQTTTPGTQPEPTRTFLPGEPPPCSPRSLEEPGLLSRAREATQDLAIIPHPVERGLPPGKAEDPSPLEGLQALRFGDLLEGGGTEATGQTNSTQGGMQSERTMDQGVPQPPLGATPQALEQITGSPGALDKDDGSQKVPDTAQLQVEEAHLEENEGDSEVDWETPNHSHPPKVLPGLDALVAATVDLGDLPDINLPDPQTQAASVPVSTAPLPHTSGIHGIALLSELADLEIQRQKSELAMQAEDEDVLAFNLQHLATLATAWSLVEAASLDSSVPSLQAPATDPDRGPRVTPRMQILQRKDTWAPKTKPVCPLKAAIDRLDTQEVEMRMQLAELQRRYKDKQRELARLQRRHDHEREESSRSPARRGPGRPRKRKHSSSLPTLRPGGQLTRSDGKKAKAVRASLSLLCAELRGDEPTRKRSKLEKSAYTGLQTASSEKVRCKKSGGQAELSSSVAHKVAQLKPRVKSKGLPTGLGAFQRKEAAPGSGYDSEDCQALLGTEAASREPGLVLHPGAGMAVLGPSPSSVVKMEANQKAKKKKERQGLLGACRLSSPEGEVKIKRRTVKSKVGPKLERAPGRRPPGAPGKKKAKGKAKSGLCAEPGAATNRDALFSPTRTFACREEGSKLASERLKRATRKSAMLQPVLRRKNGALSIALSARNAKAVLGKSRKLTKVKRETVSKQGQGRAVSRLLESFAVEDDFEFDDDSSFSDEEEEEEEASVQLSAEQSAALARSCTIHKEDLQDGLPVLIPKEDSLLYAGSVRTLQPPDIYSIVIEGERGNRPRIYSLEQLLQEAVLDVRPQSSRYLPPGTRVCAYWSQKSRCLYPGNVVRGASSDEEEDLDSVVVEFDDGDTGHIAVSNIRLLPPDFKIQCTEPSPALLVSSSCRRTKKTSSEAPQPSEAPSPSLSPKVQDGPEPSKTPGKKSISKDKAGKVDLLTSGAKSPMGASDHFLGRRGSPLLSWSAVAQTKRKAAAAAAGGKGPGMLQNLFQLNGSTKKLRARETLFPMHSMAAPVFGNSFRADSFSSLASSYTPFVGGAGAGLPGGAHKLLRAKKVERAEAEKASRRRPGGEFLVKLDHEGVTSPKNKNCKALLMGDKDFGPKLGRPLASPSYAHPALMGKDKKGRTPVHPLPMGLALRKYPLPCDSDCPSSCSDEDEDGPGLATGVPSRFLTRLSMSSSSSGSSTSSSSGSMSTSSLCSSDNEDSSYSSDDEDPALLLQTCLTRPVPALLAPPEALRSKGSSPHTHAQRCFLSRAGVAGAGAGAGPGPSGGKSKFKRKEALSFSKAKELSRRQRLPSVENRPKISAFLPARQLWKWSGNPTQRRGMKGKARKLFYKAIVRGKETLRIGDCAVFLSAGRPNLPYIGRIESLWESWGSNMVVKVKWFYHPEETKLGKRQSDGKNALYQSCHEDENDVQTISHKCQVVGREQYERMMRGRNYQDQQDLYYLAGTYDPTTGRLVTADGVPILC", "length": 2588, "header": "tr|A0A9J7GBH1-1|A0A9J7GBH1_CRIGR Computationally mapped isoform of BAH and coiled-coil domain-containing protein 1 isoform X4 OS=Cricetulus griseus OX=10029 GN=Bahcc1 PE=4 SV=1 CANONICAL=A0A8C2LS26-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H3L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS26/entry#A0A9J7H3L3-1", "sequence": { "sequence": "MDGRDFAPPPHLLSERGSLGHRSAAAAARLAPAGPAAQPAAHFQPGKYFPSPLPMASHTASSRLMGNPPASSFMGSFLTSSLGSAASAHPSGPSSSPSEPAYRGSHPATSQIWFSHSHEDNFYLRNLPPQPTILPANHNFPGVPRATPAHTIGSCSRDRIEAAPLQKGPKEFDRFLMGKELGKEKASKVAEGRERPAAEEDSSKDRQKLVPPMPTEGPCKEGGPTPRGSCEGRPKHLTSCLLNAKVLNGDMGKASLASCAGGVLGRPSTGAGAPGRCAQEVAGPVEPGAAFSECLERRQMLHHAVSYTVPSGLPTGPPPPLSTGPAGSFPCLQLHAGPDGLCPLQDKVSRDLKASGPTFVPSVGHLADKSRPFQVAEACAVAGDGKDRHLDGTMAPDHGAPYGVSYAHLKAEGKGERRPGGFEAALHPRLKGLEYLSAGPEAPFPGLPKGGLDKSGYFELPTPSQDCARPNHQDSLSGKATQACCTLDKMASKEAPAGPPGAQKVARIRHQQHLVAPEVESGGSGVDAKRKSVELASLGYSGPHMPPWGVQTGHSTSMAISEERKGSAYLDPFGSGLQQAALLSQELPTPPDEVSAMKNLLKYSNQALVVGQKAPFVGLGGLKASCVQQEAKFPATKGPGPVERPDCARSREHEAPHGDGEVRQPPVGIAVALARQKDTVSRPDAAYSTNSGRQGRAAPTFKAAGGSRATHALDLESEEERTRMCDDRLGLPGRELLLQDNKDLVEFARIHPSSSCPGDLPPHLMMQGGQLGGDPAPHPHPAHPHWLPRTRSPSLWMGGHSYGLGHPALHQSLPPGFPASVPGSMPSVFPLPQDAATQLVILPSEPTPHTNTLADVMDQASLWPPMYGARGPTSHMQHPGQLPVYSRSQLLRQQELYALQQQQQQQQQQQQQQQQQQQQQQQQRATQALELQRAAQFQRKPEDRHLELEEPAQEKAPKSTHKPVALTPMAKGTPPSATAGLVKLSPCCHSPNLKTPAGCPTPPAHPSAPCTLTVGPTGSPGPGSKVPSTKDKSGEGQRAGTDLTTLEPGLPPGLNPTAGMDFSLPADVHSSDPPDPKTMQTTTPGTQPEPTRTFLPGEPPPCSPRSLEEPGLLSRAREATQDLAIIPHPVERGLPPGKAEDPSPLEGLQALRFGDLLEGGGTEATGQTNSTQGGMQSERTMDQGVPQPPLGATPQALEQITGSPGALDKDDGSQKVPDTAQLQVEEAHLEENEGDSEVDWETPNHSHPPKVLPGLDALVAATVDLGDLPDINLPDPQTQAASVPVSTAPLPHTSGIHGIALLSELADLEIQRQKSELAMQAEDEDVLAFNLQHLATLATAWSLVEAASLDSSVPSLQAPATDPDRGPRVTPRMQILQRKDTWAPKTKPVCPLKAAIDRLDTQEVEMRMQLAELQRRYKDKQRELARLQRRHDHEREESSRSPARRGPGRPRKRKHSSSLPTLRPGGQLTRSDGKKAKAVRASLSLLCAELRGDEPTRKRSKLEKSAYTGLQTASSEKVRCKKSGGQAELSSSVAHKVAQLKPRVKSKGLPTGLGAFQRKEAAPGGRIRKKLSRARSVKVSGATQHPHPDGDGGRGMPKFPAQPAVAVPREAGSGYDSEDCQALLGTEAASREPGLVLHPGAGMAVLGPSPSSVVKMEANQKAKKKKERQGLLGACRLSSPEGEVKIKRRTVKSKVGPKLERAPGRRPPGAPGKKKAKGKAKSGLCAEPGAATNRDALFSPTRTFACREEGSKLASERLKRATRKSAMLQPVLRRKNGALSIALSARNAKAVLGKSRKLTKVKRETVSKQGQGRAVSRLLESFAVEDDFEFDDDSSFSDEEEEEEEASVQLSAEQSAALARSCTIHKEDLQDGLPVLIPKEDSLLYAGSVRTLQPPDIYSIVIEGERGNRPRIYSLEQLLQEAVLDVRPQSSRYLPPGTRVCAYWSQKSRCLYPGNVVRGASSDEEEDLDSVVVEFDDGDTGHIAVSNIRLLPPDFKIQCTEPSPALLVSSSCRRTKKTSSEAPQPSEAPSPSLSPKVQDGPEPSKTPGKKSISKDKAGKVDLLTSGAKSPMGASDHFLGRRGSPLLSWSAVAQTKRKAAAAAAGGKGPGMLQNLFQLNGSTKKLRARETLFPMHSMAAPVFGNSFRADSFSSLASSYTPFVGGAGAGLPGGAHKLLRAKKVERAEAEKASRRRPGGEFLVKLDHEGVTSPKNKNCKALLMGDKDFGPKLGRPLASPSYAHPALMGKDKKGRTPVHPLPMGLALRKYPLPCDSDCPSSCSDEDEDGPGLATGVPSRFLTRLSMSSSSSGSSTSSSSGSMSTSSLCSSDNEDSSYSSDDEDPALLLQTCLTRPVPALLAPPEALRSKGSSPHTHAQRCFLSRAGVAGAGAGAGPGPSGGKSKFKRKEALSFSKAKELSRRQRLPSVENRPKISAFLPARQLWKWSGNPTQRRGMKGKARKLFYKAIVRGKETLRIGDCAVFLSAGRPNLPYIGRIESLWESWGSNMVVKVKWFYHPEETKLGKRQSDGKNALYQSCHEDENDVQTISHKCQVVGREQYERMMRGRNYQDQQDLYYLAGTYDPTTGRLVTADGVPILC", "length": 2595, "header": "tr|A0A9J7H3L3-1|A0A9J7H3L3_CRIGR Computationally mapped isoform of BAH and coiled-coil domain-containing protein 1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Bahcc1 PE=4 SV=1 CANONICAL=A0A8C2LS26-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1042, "start_aa": "Thr", "end_pos": 1042, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1042", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1058, "start_aa": "Thr", "end_pos": 1058, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1058", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1411, "start_aa": "Thr", "end_pos": 1411, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1411", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 188, "start_aa": "Thr", "end_pos": 188, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr188", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 256, "start_aa": "Thr", "end_pos": 256, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr256", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 266, "start_aa": "Thr", "end_pos": 266, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr266", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LS26", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS26" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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beta subunit", "type": "synonym", "evidence": [ { "id": "A0A8C2LS78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS78/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615656.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003512971", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512971" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LS78", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS78" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ap5b1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS78", "locus": {} } ], "crossref": [ { "id": "100761023", "url": "https://www.ncbi.nlm.nih.gov/gene/100761023", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR038741", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038741", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048981", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048981", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761023", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761023", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SHHLEPF", "url": "https://omabrowser.org/oma/group/SHHLEPF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LS78", "url": "https://www.orthodb.org/?gene=A0A8C2LS78", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34033", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34033", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34033:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34033:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21587", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21587", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21588", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21588", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21589", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21589", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21590", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21590", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003512971", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003512971", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LS78", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LS78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS78-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPLSREAWAQRLGAFRASPSAFLAGAEGEDLGRDLLSDLRSEKLSEQTKVSLLTLSLEYSDKLWSDAPAAEAAATSLLDTLVLLPSKPSALRRLLLLAATTALVSGGALGPTSGASCRLLPLLLGLASGRDMGRSFGTLSEQRHLQATACECLGELERCKPGLLAGSLGILRSLLGQTGPIQPVSLLLALVLHNTLVVPSRPGAEIGAGLQGLLVAGVSSSGSCPWDWTLAEEWDAHLQPQAPSWPTTGEEHGFPLLKPSPEEARELKAAVAQLLDTSYLLTSVAQAQLLWLLGWALRGLRGQPPVVFKPQLVRLLGTAQLTLLHSVLALKAAFGEALFTAQDEALLLRRLTLVAQHPALPSPTHLFYLNCILSFPENCPLGLEGEEAAPLLLGPQLSRGLMPSLLHDPMVLLARLHLLCLLCADAEEEEKGHVHSPRWYLQELLAGLQQRAALDGGPQALATLCFQASYLVASCLAGQPTVRTSLVHGLAQLYRARPSLAPHFVDLLDQVSPELREPLRVVLQQEVVARPGKNESLCWHLRMLAKVAEGDAQRATLSFLQAAAIHCTDWGLQQALLRVCRALLRTGGGDGLADLLQVLARQLEDADGRDHARLYYILFSHLSSSKLGMALGPSLAVPALASSLVAENQGFASTLMVQETPAPIQLSVGPQKAKGTLPVLHLQVEALEAPVYSLELRFRVAGQLYGPLEAVHIPCLCPGQPAHPLCLTLQPRRPAPARLHVEALYTTPAGLTCHAHLHPLSVKFADLFLPFPQLPKGSELCFFDDLWNSCLPKGVESRMWCPLGPQGLEALVSQHLEPFVVVAQPPTTYLIAVQLPPDSMLLLRLEKAQVDGVPVALRTDNWAVLPLVGDYLRSLAAH", "length": 879, "header": "tr|A0A8C2LS78-1|A0A8C2LS78_CRIGR Isoform 1 of AP-5 complex subunit beta-1 OS=Cricetulus griseus OX=10029 GN=Ap5b1 PE=4 SV=1 CANONICAL=A0A8C2LS78-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LS78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS78/entry#A0A8C2LS78-1", "sequence": { "sequence": "MGPLSREAWAQRLGAFRASPSAFLAGAEGEDLGRDLLSDLRSEKLSEQTKVSLLTLSLEYSDKLWSDAPAAEAAATSLLDTLVLLPSKPSALRRLLLLAATTALVSGGALGPTSGASCRLLPLLLGLASGRDMGRSFGTLSEQRHLQATACECLGELERCKPGLLAGSLGILRSLLGQTGPIQPVSLLLALVLHNTLVVPSRPGAEIGAGLQGLLVAGVSSSGSCPWDWTLAEEWDAHLQPQAPSWPTTGEEHGFPLLKPSPEEARELKAAVAQLLDTSYLLTSVAQAQLLWLLGWALRGLRGQPPVVFKPQLVRLLGTAQLTLLHSVLALKAAFGEALFTAQDEALLLRRLTLVAQHPALPSPTHLFYLNCILSFPENCPLGLEGEEAAPLLLGPQLSRGLMPSLLHDPMVLLARLHLLCLLCADAEEEEKGHVHSPRWYLQELLAGLQQRAALDGGPQALATLCFQASYLVASCLAGQPTVRTSLVHGLAQLYRARPSLAPHFVDLLDQVSPELREPLRVVLQQEVVARPGKNESLCWHLRMLAKVAEGDAQRATLSFLQAAAIHCTDWGLQQALLRVCRALLRTGGGDGLADLLQVLARQLEDADGRDHARLYYILFSHLSSSKLGMALGPSLAVPALASSLVAENQGFASTLMVQETPAPIQLSVGPQKAKGTLPVLHLQVEALEAPVYSLELRFRVAGQLYGPLEAVHIPCLCPGQPAHPLCLTLQPRRPAPARLHVEALYTTPAGLTCHAHLHPLSVKFADLFLPFPQLPKGSELCFFDDLWNSCLPKGVESRMWCPLGPQGLEALVSQHLEPFVVVAQPPTTYLIAVQLPPDSMLLLRLEKAQVDGVPVALRTDNWAVLPLVGDYLRSLAAH", "length": 879, "header": "tr|A0A8C2LS78-1|A0A8C2LS78_CRIGR Isoform 1 of AP-5 complex subunit beta-1 OS=Cricetulus griseus OX=10029 GN=Ap5b1 PE=4 SV=1 CANONICAL=A0A8C2LS78-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 113, "start_aa": "Thr", "end_pos": 113, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr113", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LS78", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS78" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LS78", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS78" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761023", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761023", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZVB0-1", "protein_name": "AP-5 complex subunit beta-1", "gene_name": "Ap5b1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGPLSREAWAQRLGSFRASPSAFLAGAEGEDLGHDLLSDLRSEKLSELIKVSLLTLSLEYSDKLWPDALAAEAAATSLLDTLVLLPSKPSALRRLLLLAATTALVSGGALGPTSEASSRLLPLLLGLASGQDMGRSFGTTSEQRHLQATACECLGELERCKPGLLAGALGVLRSLLGQKGPIQPVSLLLALVLHNTLVVQSRFGAGLQGLLVAKDSSPGSCPWDWTLAEEWDDHLKPQAHGWPTAGEEERDFPILDPNPEDTRELKAAVAQLLDTSYLLTPVAQAQLVWLLGWALQGLRGQPPVLFKPQLVRLLGTAQLTLLHSVLSLKAAFGEALFTAQDEALLLRRLTLVAQHPALPSPTHLFYLHCILSFPENCPLGPEGEEAAPLLLGPQLRRGLMPSLLHDPMVLLARLHLLCLLCADDEEEEKGQLQGPQWFLQELLAGLQQRAAVDGGPRALATLCFQASYLVTSCLTRQPTVQTSLVHGLAQLYRARPSLAPHFVDLLDEVSPELREPLRKVLLREVVARPGKNEALRWHLQMLAKVAEGATQSAILGFLQAAAIHCTDWGLHQALLRVCRALLRTGGGEGLADLLQELARQLENADGRDHARLYYVLLSHLSSSKLGMALGPSLAAPALASSLMAENQGFASALMVQETSAPIQLSVGPQKAKGPLPVLHLQVQALDTPVYSLELRFRVEGQLYEPVEAVHIPSVRPGQPAHPLHLPLQPRSPAPARLHVRALYTTPAGLTCHAHLPPLSVNFADLFLPFPQLPKGSELCFFDELWNSCLPKGVESRVWCPLGPQGLEALVSQHLEPFVVVAQPPTTYLIAVRLPPHSMLLLRLEKAQVHGVPVALRTDDWAVLPLVGDYLRGLAAH", "length": 876 }, "evidence": [ { "id": "A0A8C2LS78", "url": "https://omabrowser.org/oma/group/A0A8C2LS78/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QPU4-1", "protein_name": "AP-5 complex subunit beta-1", "gene_name": "ap5b1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTIADLWDQRISAFLLSPSQFLATSTSEIFLAELLHELRNDKINDQLKILLVSALLEHPTILCPSASVGEETALELLSIFSQTPQKSISLKCNVMLAITNVIICTSCLATHTKMAEDWLDLLFQTIQDTNDYRCGQSQQPLRATACDCLREMETCSPGLLSQKLEALYLLKQQETSVLHQSYCILYTLGLKNAIRILTNQKEVTDFEFKSILGGNEGFAWRTNQNFLPINMIVQVPQLPQGLDCKELKSIMSLLLEESYLLTPISQSSLMRDLVEVVAMVPGLSPTLFKSQLLRLFGTAEVVLMHATLFMKDTFTDSLFTAEDENFLLKRLVGSAQHPLLRIPEKLFYMDCILHFPENRPISSSGEECLPVLVTPRLAASLLPTVFNDSATMLCRLNLLCLVHLEADEGEADKGIAYLFDHIMALLKIVDSDGSREVVVTSFRALFIFLKHFNGMEELSEKLIDKLRDIYSRHCRLAPNLIGLADRIQECLDDPIWSVKLLRGLQKCIMEMPPLQLTIHNLSWHLKVLKRVAKEGQITQRNTIYLLLNVLINSNLCERGKWQIGNAVLAVCRNLLEHPSIDQVFIELADLLQYISVNYNDTDIKDHARFYYTLLTNLSWEKLTGVLAKGPDGGRAKERSHSAIMAESEGIASNLTVCKTERHVLQLIKIQDKVSQSTSESSESLEDTGEARNWLEVYQEQFQTPGFGSEVTLRYNLTHAEETDPLFDRVFSICLHFEFKDSNYAKVSDIHVPCVFRDRKPPEVNVQLKPFQPYPTTLCFSAMFTTQDGRSWHSQLPDVSISFPEIFLPLPIATNASSACREQVFDHIWESAASGNPDKSAISLFCFKPGDESLADLIKTHFQGYLITDQQSERFWKVLFFLPPMCHVLLRITQAEDAVQVSIATDNWELLPFVNSYLRNITDDCSTTVTDG", "length": 931 }, "evidence": [ { "id": "A0A8C2LS78", "url": "https://omabrowser.org/oma/group/A0A8C2LS78/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RRK6-1", "protein_name": "AP-5 complex subunit beta-1", "gene_name": "AP5B1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGPQSRETWAQRLGTFRASPSAFMEGPEGEDLARDLLSDLRSEKLSEPTKVSLLALSLEYPTQLWPDASAAEAAANSLLDTLVLLPPRPSALRRPLLLAATTALAAGGALGPTSGASRRLLPLLLGLASGRDLGRGFSPASEQRPLQATAWECLRELESCKPGLLGGCLGLLRGLLGQEGPVQPLSLLLALALRNALMIQARARASLQGLLTAGDCPTEGAPWNWTLAEAGDAHLQPQAPSWPAAEEGECGLTALELSPEEARELRAAVAQLLDASYLLTPVAQAQLLWLLGWALRGLRGQPPVLFKPQLVRLLGTAQLTLLHAVLALKAAFGEALFTAQDEALLLRRLILAAQHPALPLPAHLFCLHCLLSFPENWPLGPAGEEAAPLLLGSQLCRGLLPSLLHDPMALLARLHLLCLLCVEDEDKEEQGQDPSPRRYLEELLAGLRQRAALDGGPRALATLCFQASYLVARCLAGHPVVLTPLTHGLAQLYRARPALTPHFADLLDQVGPELGEPLKVVLRQEVVSRPGRDEALRWHLQMLAKVADGDAQGATLSFLQAAATHCTDWGLQQALLKVCRALLRAGVVRGLADLLQALARQLEDPDGRDHARLYYILLAHLARPKLGVALGPSLAAPALASSLVAENQGFAKALMVQEAPAPIRLSLGPRRAEGPVPVLQLQVEVLEPVYSLELRFSVERQLYAPLGAVHVPCLCPSRPARPLLLPLQPRRPAPARLAVRALYTTPAGLTCHAHLPPLLVNFADLFLPFPQPPEGAKVDFFEELWDSCLPKGAESHLWCPLGPHGLEALVSRHLEPFVVVAQPPTSYCVAIRLPPNSKLLLRLEAAQADGVPVALRTDDWAVLPLVGDYLRGLAAAG", "length": 877 }, "evidence": [ { "id": "A0A8C2LS78", "url": "https://omabrowser.org/oma/group/A0A8C2LS78/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3MZC5-1", "protein_name": "AP-5 complex subunit beta-1", "gene_name": "AP5B1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGPLGRETWAQRLGTFRASPSAFMAGPEGEDLGRDLLSDLRSEKLSEPMKVALLALSLEYPDQLWPDAPAAEAAATSLLDTLVLLPPRPSALRRPLLLAATTALAAGGALNPASGASGRLLPLLLGLASGRDLGRSFCPASEQRPLQATAWECLRELESCRPGLLGGCLGLLRALLGREGPAQPLSLLLALALRNALVIQARAGAGLQGLLTAGESSMEGGPWNWMLAEEGEVHLQPQAPSWPAAEEDECGLAALELSPEEARELRATVAQLLDASYLLTPVAQAQLLWLLGWALRGLRGQPPVLFKPQLVRLLGTAQLTLLHAMLALKAAFGEALFTAQDEALLLRRLTLAAQHPALPLPTHLFYLHCLLNFPENWPLGPTGEEAAPLLLGSQLCRGLLPSLLHEPMALLARLHLLCLLCVEDEEKEGKGQDRSPRHYLEELLAGLRQRAALDGGPRALATLCFQASYLVAHCLAGQPVVLIPLTQGLAQLYRARPALAPHFVDLLDHVGPELQEPLRVALRQEVASRPGREEALRWHLQMLASVADGDAQSATLSFLRAAAAHCTDWGLQQALLRVCRALLRAGVGGGLADLLQELARQLEDPDGQDHARLYYILLAHLAGPKLGVALGPSLAAPALASSLVAENQGFAAALMVQEAPAPIRLSVGPRRAEGAVPVLRLQVEVLEPVYSLELRFRVEGQLYAPLGAVHVPCLCPGRPTRPLLLPLQPRRPAPARLAVRALYSTPSGLTCHAHLPPLLVAFADLFLPFPQPPEGAQLDFFEELWDSCLPKGTESRLWCPLGPEGLEALVSRHLEPFVVVAQPPVSYLVAIRLPPDSRLLLRLEAAQADGVPVALRTDDWAVLPLAGDYLRGLSAAG", "length": 877 }, "evidence": [ { "id": "A0A8C2LS78", "url": "https://omabrowser.org/oma/group/A0A8C2LS78/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q2VPB7-1", "protein_name": "AP-5 complex subunit beta-1", "gene_name": "AP5B1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGPLSRDAWAQRLGAFRASPSAFMAGPEGEDLGRDLLSDLRSEKLSEQTKVSLLALSMEYPAQLWPDASAAEVAATSLLDTLVLLPPRPSALRRPLLLAATTALAAGGALGPTSGASCRLLPLLLGLAAGSDLGRGFVPASEQRPLQATACECLRELESCKPGLLGGSLGLLRGLLGQEGPVQPLSLLLALALRNTLVLQSRVGAGLGGLLTDKVSPTGGGPWDWTLVEEGDGRLQPQAPSWPAAEEGEGERSLTAREHSPEEARELRAAVIQLLDTSYLLTPVAQAQLLWLLGWALRGLQGQPPALFKPQLVRLLGTAQLTLLHAMLALKAAFGEALFTAQDEALLLRRLTLAAQHPALPPPTHLFYLHCVLSFPENWPLGPEGEEAAPLLLGPQLCRGLLPSLLHDPMALLARLHLLCLLCAEEEEEEKGQLPSPRHYLEELLAGLRQRAALDGGPRALATLCFQASYLVACCLAGQPTVLTPLIHGLAQLYQARPMLAPHFVDLLDQVDSELREPLKVVLRQVVVSRPGRDEALCWHLQMLAKVADGDAQSATLNFLQAAAAHCTNWDLQQGLLRVCRALLRAGVRGGLVDLLQVLARQLEDPDGRDHARLYYILLAHLAAPKLGVALGPSLAAPALASSLVAENQGFVAALMVQEAPALVRLSLGSHRVKGPLPVLKLQPEALEPIYSLELRFRVEGQLYAPLEAVHVPCLCPGRPARPLLLPLQPRCPAPARLDVHALYTTSTGLTCHAHLPPLFVNFADLFLPFPQPPEGAGLGFFEELWDSCLPEGAESRVWCPLGPQGLEGLVSRHLEPFVVVAQPPTSYCVAIHLPPDSKLLLRLEAALADGVPVALRTDDWAVLPLAGDYLRGLAAAV", "length": 878 }, "evidence": [ { "id": "A0A8C2LS78", "url": "https://omabrowser.org/oma/group/A0A8C2LS78/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3TAP4-1", "protein_name": "AP-5 complex subunit beta-1", "gene_name": "Ap5b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGPLGREAWAQRLGAFRASPSAFLAGAEGEDLGRDLLSDLRSEKLSEQTKVSLLTLSLEYSDKLWPDAPAAEAAATSLLDTLVLLPTRPSALRRLLLLAATTALVSGDALGPTSGASCRLLPLLLGLASGRDLGRSFGTPSEQRHLQATACECLGELERCKPGLLAGALGMLRSLPGQTGPIQPVSLLLALVLHDTLVVQSRSGAGLQGLLVAEDFSTGSCPWDWTLAEEWDAHLKPQGPSWPTAGEEERGFPVLEPSPEDARELKAAVAQLLDTSYLLTPVAQAQLLWLLGWALRGLRGQPPVLFKPQLVRLLGTAQLTLLHSVLSLKAAFGEALFTAQDEALLLRRLTLGAQHPALPSPTHLFYLHCILSFPENCPLGPEGEEAAPLLLGPQLCRGLMPSLLHDPTVLLARLHLLCLLCADDEEEEKDQTQGPQWFLQEVLAGLQQRAALDGGPRALATLCFQASYLVTNCLTRHSTVQTFLIRGLAQLYRARPSLAPHFVDLLDQVSPELREPLREVLLQEAVARPGESEALCWHLQMLAKVAEGATQSTTLSFLQAAAVHCTDWGLHQALLRVCRALLRTGGGDGLANLLQELARQLENADGRDHARLYYVLLSHLSSSKLGMALGPSLAAPALASSLMAENQGFSSALMVQETSAPIQLSVGPQQAKGPLPVLCLQVQALDAPVYSLELRFRVEGQLYEPLEAVHIPCLRPGQPAHPLYLLLQPRCPAPARLHVRALYSTSAGLTCHARLPPLSVNFADLFLPFPRLPKGSELRFFDELWNSCLPKGVESRVWCPLGQQGLEALVSQYLEPFVVLAQPPTTYLIAIRLPPASMLLLRLEKAQVDGVPVALRTDDWAVLPLVGDYLRGLAAH", "length": 876 }, "evidence": [ { "id": "A0A8C2LS78", "url": "https://omabrowser.org/oma/group/A0A8C2LS78/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LS78", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS78" } ], "pmid": "" }, { "name": "endosomal transport", "id": "GO:0016197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016197", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LS78", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS78" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LS78", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS78" } ], "pmid": "" }, { "name": "AP-type membrane coat adaptor complex", "id": "GO:0030119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030119", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LS78", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS78" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 535, "end_pos": 537, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LS78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS78" }, { "id": "PF21587", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21587" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AP-5 complex subunit beta-1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 104, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2LS78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS78" }, { "id": "PF21589", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21589" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AP-5 complex subunit beta-1 beta-barrel", "eco_id": "ECO_0000259", "start_pos": 692, "end_pos": 761, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2LS78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS78" }, { "id": "PF21590", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21590" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AP5B1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 783, "end_pos": 876, "start_aa": "Phe", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2LS78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS78" }, { "id": "PF21588", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21588" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AP5B1 middle", "eco_id": "ECO_0000259", "start_pos": 264, "end_pos": 628, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 113 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 535, "end_pos": 537 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LS99-1", "uniprot_ac": "A0A8C2LS99", "uniprot_id": "A0A8C2LS99_CRIGR", "mass": { "chemical_mass": 40309.0, "monoisotopic_mass": 40309.0 }, "refseq": { "ac": "XP_027265489", "name": "growth arrest-specific protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265489" }, "gene_names": [ { "name": "LOC113835048", "type": "recommended", "evidence": [ { "id": "A0A8C2LS99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS99" } ] }, { "name": "LOC113835048", "type": "synonym", "evidence": [ { "id": "XP_027265489", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265489" } ] } ], "protein_names": [ { "name": "Growth arrest-specific protein 1", "type": "synonym", "evidence": [ { "id": "A0A8C2LS99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LS99/entry#names_and_taxonomy" } ] }, { "name": "growth arrest-specific protein 1", "type": "synonym", "evidence": [ { "id": "XP_027265489", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027265489" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003510120", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510120" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LSF0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LSF0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Slc10a5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LSF0", "locus": {} } ], "crossref": [ { "id": "100760229", "url": "https://www.ncbi.nlm.nih.gov/gene/100760229", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002657", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002657", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004710", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004710", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057103", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057103", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760229", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760229", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AWMAHFR", "url": "https://omabrowser.org/oma/group/AWMAHFR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LSF0", "url": "https://www.orthodb.org/?gene=A0A8C2LSF0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10361", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10361", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10361:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10361:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01758", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01758", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003510120", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510120", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LSF0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LSF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LSF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LSF0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFGNFFLILLLLVTPGEARKSFLSFLNIQNTEILSFAKTEETVVVRSSYKDKRPNSSYLFVKLEDPKVLQVVNVTKTLLDVTDFTISLMTSPGETNLTIQLWDSEGRQKILIEEIKNVKVKVLLQTKGSLFQAPMHVNRYILMLILSMVLLNKCAFGCKIEFQVLQTVWKKPLPVVLGTVTQFFLMPFCGFLLSQIFGLSKAQAFGFVLTCTCPGGGGGYLFALLLEGDITLAILMTCTSTTLALIMMPVNSYLYSRLLGLPGVFHVPVLKIVSTLLFILTPISIGVVIKHKTPQKAACLERVVRPLSLTLMFVGIYLAFRMGLVFLRMANLDMLLLGLLVPALGFLFGYSFAKVSMLPLPVCKTVAIESGMLNSFLALAIIQLSFSQSKAYEASVAPFTTAMCSGCEMLLLLLIYKGKKRGILSTGTEKTPLV", "length": 434, "header": "tr|A0A8C2LSF0-1|A0A8C2LSF0_CRIGR Isoform 1 of Sodium/bile acid cotransporter 5 OS=Cricetulus griseus OX=10029 GN=Slc10a5 PE=3 SV=1 CANONICAL=A0A8C2LSF0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LSF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LSF0/entry#A0A8C2LSF0-1", "sequence": { "sequence": "MFGNFFLILLLLVTPGEARKSFLSFLNIQNTEILSFAKTEETVVVRSSYKDKRPNSSYLFVKLEDPKVLQVVNVTKTLLDVTDFTISLMTSPGETNLTIQLWDSEGRQKILIEEIKNVKVKVLLQTKGSLFQAPMHVNRYILMLILSMVLLNKCAFGCKIEFQVLQTVWKKPLPVVLGTVTQFFLMPFCGFLLSQIFGLSKAQAFGFVLTCTCPGGGGGYLFALLLEGDITLAILMTCTSTTLALIMMPVNSYLYSRLLGLPGVFHVPVLKIVSTLLFILTPISIGVVIKHKTPQKAACLERVVRPLSLTLMFVGIYLAFRMGLVFLRMANLDMLLLGLLVPALGFLFGYSFAKVSMLPLPVCKTVAIESGMLNSFLALAIIQLSFSQSKAYEASVAPFTTAMCSGCEMLLLLLIYKGKKRGILSTGTEKTPLV", "length": 434, "header": "tr|A0A8C2LSF0-1|A0A8C2LSF0_CRIGR Isoform 1 of Sodium/bile acid cotransporter 5 OS=Cricetulus griseus OX=10029 GN=Slc10a5 PE=3 SV=1 CANONICAL=A0A8C2LSF0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LSF0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LSF0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LSF0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LSF0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760229", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760229", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9SHV1-1", "protein_name": "Inositol monophosphatase 1", "gene_name": "SLC10A5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MIRKLFIILLLSSVTLGEARKSFLSFLNIEKTEVLFITKTEETVVVRSSYRDKQPNSSYLRVQLEDDKMLQVVNVTKTLSDVTNFTIHLVTGGDGETNLTVQLWDSEGRRERLIEEIKNVRVRVLRQRQDSPFQASNLINRNILMLFLPMILLNKCAFGCKIEFQVFETVWKRPLPVVLGAVIQFFLMPFCGFLLTQILALPEAQAFGFIVTCTCPGGGGGYLFALLLEGDVTLAILMTCTSTFLALVTMPTNSYIYSRILGLSGTLHIPISKIMSTLLFILAPMSVGIVIKHRLPDKAKFLERIIRPLSFILMFIGIYVTFSMGLVFLKTVNLGVLLLGVLVPALGLLFGYFFAKISMLPLPVCKTVAIEGGVLNSFLALAIIQLSFSQSDADLASVAPFTVAMCSGCEMLLILLFYKAKKRCILNIEEKRMKNPPV", "length": 438 }, "evidence": [ { "id": "A0A8C2LSF0", "url": "https://omabrowser.org/oma/group/A0A8C2LSF0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5PT54-1", "protein_name": "Sodium/bile acid cotransporter 5", "gene_name": "Slc10a5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGNFFIFLLLLVTPGEAKKSFLSFLNIQNTEMLSFTRTEENIVVRSSYKDKQPHSSYLLVKLEDPKVLQVVNVTKTSLAVTDFTVNLKTFPGETNVTLQLWESEGRQTTLIDELKNVRVRVFRQTDDSLLQAPIHVDSSIFLLVLSMILLNKCAFGCKIEFQVLQTVWKRPLPILLGVVIQFFLMPFCGFLLSQILGLPKAQAFGFVMTCTCPGGGGGYLFALLLEGDVTLAILMTCTSTSLALIMMPVNSYFYSRLLGLAGAFHVPVLKIVSTLLFILMPMSTGVIIKHKMPAKAICLERVVRPLSLTLMFVGIYLAFRMGLVFLRMANLEVFLLGLLVPALGLLFGYSLAKVYLLPLPVCKTVALETGMLNSFLALAIIQLSFSQPKAHEASVAPFTVAMCSSCEMLLLLLVYKAKRRPSLSTEYEKTPLV", "length": 434 }, "evidence": [ { "id": "A0A8C2LSF0", "url": "https://omabrowser.org/oma/group/A0A8C2LSF0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5PT55-1", "protein_name": "Sodium/bile acid cotransporter 5", "gene_name": "SLC10A5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIRKLFIVLLLLLVTIEEARMSSLSFLNIEKTEILFFTKTEETILVSSSYENKRPNSSHLFVKIEDPKILQMVNVAKKISSDATNFTINLVTDEEGETNVTIQLWDSEGRQERLIEEIKNVKVKVLKQKDSLLQAPMHIDRNILMLILPLILLNKCAFGCKIELQLFQTVWKRPLPVILGAVTQFFLMPFCGFLLSQIVALPEAQAFGVVMTCTCPGGGGGYLFALLLDGDFTLAILMTCTSTLLALIMMPVNSYIYSRILGLSGTFHIPVSKIVSTLLFILVPVSIGIVIKHRIPEKASFLERIIRPLSFILMFVGIYLTFTVGLVFLKTDNLEVILLGLLVPALGLLFGYSFAKVCTLPLPVCKTVAIESGMLNSFLALAVIQLSFPQSKANLASVAPFTVAMCSGCEMLLIILVYKAKKRCIFFLQDKRKRNFLI", "length": 438 }, "evidence": [ { "id": "A0A8C2LSF0", "url": "https://omabrowser.org/oma/group/A0A8C2LSF0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VXV4-1", "protein_name": "P3 protein", "gene_name": "Dmel\\CG11655", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSPHGRPGWEWSYLLLTLAVGFASTHGWMAHFRPAALTLQMERGDRVQLKLENVAPSTLQQPTRYHFRLESVDTDLASVPGENATISLDVFNTDTRDWTGDIVVNGHFLGQTKIQVKLYDSQRNTSELPTNWSNDSTLDVKIKRPKRVVDDIFLGTIILLMSLLYISFGAALNLDVLRGLITRPTGPCIGFVMQVVGMPLLSYALGVFIFPQAPAMQLGLFFTGISPSGGASNTWSAVLGGNIHLSVLMTTVSNVAAFATIPLWTITLGQLIFERAGIKVPYGKIASYSSSLVLPLLLGLLVQKRMPQVARVLVRLLKPVSAFIILFIIVFAIINNFYLFYLFSWQIVVAGMALPGLGYIFAFLAAKLLHQNAADALTIAIETGIQNTGIAIFLLTTTLESPEADITTVVPVSVAVMTPLPLLGIYLYNRCWGNKRISEASATASEAERIAGAIH", "length": 455 }, "evidence": [ { "id": "A0A8C2LSF0", "url": "https://omabrowser.org/oma/group/A0A8C2LSF0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LSF0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LSF0" } ], "pmid": "" } ] }, { "name": "Molecular 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"Domain_Extent_Annotation", "uniprotkb_annotation": "NTCP5/P3 N-terminal", "eco_id": "ECO_0000259", "start_pos": 28, "end_pos": 122, "start_aa": "Ile", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 55, "end_pos": 57 }, { "start_pos": 73, "end_pos": 75 }, { "start_pos": 96, "end_pos": 98 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", 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}, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LSH9-1", "uniprot_ac": "A0A8C2LSH9", "uniprot_id": "A0A8C2LSH9_CRIGR", "mass": { "chemical_mass": 9142.0, "monoisotopic_mass": 9142.0 }, "refseq": { "ac": "XP_035302082", "name": "cortexin-2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302082" }, "gene_names": [ { "name": "Ctxn2", "type": "recommended", "evidence": [ { "id": "A0A8C2LSH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LSH9" } ] }, { "name": "Ctxn2", "type": "synonym", "evidence": [ { "id": "XP_035302082", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302082" } ] } ], "protein_names": [ { "name": "Cortexin-2", "type": "synonym", "evidence": [ { "id": "A0A8C2LSH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LSH9/entry#names_and_taxonomy" } ] }, { "name": "cortexin-2", "type": "synonym", "evidence": [ { "id": "XP_035302082", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035302082" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048599.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_003616693.1) annotated using gene prediction method: Gnomon. 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Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304101", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304101" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LSJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LSJ3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Gp1ba", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LSJ3", "locus": {} } ], "crossref": [ { "id": "100770316", "url": "https://www.ncbi.nlm.nih.gov/gene/100770316", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007644890", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644890" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LSW3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LSW3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mlf2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LSW3", "locus": {} } ], "crossref": [ { "id": "100766182", "url": "https://www.ncbi.nlm.nih.gov/gene/100766182", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019376", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019376", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766182", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766182", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LSW3", "url": "https://www.orthodb.org/?gene=A0A8C2LSW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10248", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10248", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007644890", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007644890", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LSW3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LSW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LSW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LSW3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GJS5", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GJS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJS5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFRFMRDVEPEDPMFLMDPFAIHRQHMSRMLSGGFGYSPFLSITDGNMPATRPASRRMQTGAVSPFGMLGMSGGFMDMFGMMNDMIGNMEHMAAGGNCQTFSSSTVISYSNTGDGAPKVYQETSEMRSAPGGIRETRRTVRDSDSGLEQMSIGHHIRDRAHILQRSRNHRTGDQEERQDYINLDESEAAAFDDEWRRETSRFRQQRPLEFRRHEASVGGGRRAEGPPRLAIQGPEDSPSRQSRRYDW", "length": 247, "header": "tr|A0A8C2LSW3-1|A0A8C2LSW3_CRIGR Isoform 1 of Myeloid leukemia factor 2 isoform X3 OS=Cricetulus griseus OX=10029 GN=Mlf2 PE=3 SV=1 CANONICAL=A0A8C2LSW3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LSW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LSW3/entry#A0A8C2LSW3-1", "sequence": { "sequence": "MFRFMRDVEPEDPMFLMDPFAIHRQHMSRMLSGGFGYSPFLSITDGNMPATRPASRRMQTGAVSPFGMLGMSGGFMDMFGMMNDMIGNMEHMAAGGNCQTFSSSTVISYSNTGDGAPKVYQETSEMRSAPGGIRETRRTVRDSDSGLEQMSIGHHIRDRAHILQRSRNHRTGDQEERQDYINLDESEAAAFDDEWRRETSRFRQQRPLEFRRHEASVGGGRRAEGPPRLAIQGPEDSPSRQSRRYDW", "length": 247, "header": "tr|A0A8C2LSW3-1|A0A8C2LSW3_CRIGR Isoform 1 of Myeloid leukemia factor 2 isoform X3 OS=Cricetulus griseus OX=10029 GN=Mlf2 PE=3 SV=1 CANONICAL=A0A8C2LSW3-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GJS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LSW3/entry#A0A9J7GJS5-1", "sequence": { "sequence": "MFRFMRDVEPEDPMFLMDPFAIHRQHMSRMLSGGFGYSPFLSITDGNMPATRPASRRMQSGGFMDMFGMMNDMIGNMEHMAAGGNCQTFSSSTVISYSNTGDGAPKVYQETSEMRSAPGGIRETRRTVRDSDSGLEQMSIGHHIRDRAHILQRSRNHRTGDQEERQDYINLDESEAAAFDDEWRRETSRFRQQRPLEFRRHEASVGGGRRAEGPPRLAIQGPEDSPSRQSRRYDW", "length": 235, "header": "tr|A0A9J7GJS5-1|A0A9J7GJS5_CRIGR Computationally mapped isoform of Myeloid leukemia factor 2 isoform X4 OS=Cricetulus griseus OX=10029 GN=Mlf2 PE=3 SV=1 CANONICAL=A0A8C2LSW3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NW_003615806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003513291", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003513291" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LSZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LSZ2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "CUNH4orf36", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LSZ2", "locus": {} } ], "crossref": [ { "id": "100758616", "url": "https://www.ncbi.nlm.nih.gov/gene/100758616", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027825", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027825", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758616", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758616", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YEVQEPW", "url": "https://omabrowser.org/oma/group/YEVQEPW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LSZ2", "url": "https://www.orthodb.org/?gene=A0A8C2LSZ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR38002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR38002:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38002:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15022", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15022", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003513291", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003513291", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LSZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LSZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LSZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LSZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAYGLPRRNTVQTILKGSCYKIQEPWDLAELTKIWYTNLMKIRLPFLGEIAFGSPIKLVTRKTFKDELQPSLECIKLEKEFEMKRLTTLKNQEQACEEIQVALRQTRVGLRRPLQPK", "length": 117, "header": "tr|A0A8C2LSZ2-1|A0A8C2LSZ2_CRIGR Isoform 1 of Uncharacterized protein C4orf36 homolog OS=Cricetulus griseus OX=10029 GN=CUNH4orf36 PE=4 SV=1 CANONICAL=A0A8C2LSZ2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LSZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LSZ2/entry#A0A8C2LSZ2-1", "sequence": { "sequence": "MAYGLPRRNTVQTILKGSCYKIQEPWDLAELTKIWYTNLMKIRLPFLGEIAFGSPIKLVTRKTFKDELQPSLECIKLEKEFEMKRLTTLKNQEQACEEIQVALRQTRVGLRRPLQPK", "length": 117, "header": "tr|A0A8C2LSZ2-1|A0A8C2LSZ2_CRIGR Isoform 1 of Uncharacterized protein C4orf36 homolog OS=Cricetulus griseus OX=10029 GN=CUNH4orf36 PE=4 SV=1 CANONICAL=A0A8C2LSZ2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495347" }, "gene_names": [ { "name": "Ankrd28", "type": "recommended", "evidence": [ { "id": "A0A8C2LT32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LT32" } ] }, { "name": "Ankrd28", "type": "synonym", "evidence": [ { "id": "XP_003495347", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495347" } ] } ], "protein_names": [ { "name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8C2LT32", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LT32/entry#names_and_taxonomy" } ] }, { "name": "serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003495347", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495347" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613589.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003495347", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495347" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LT32", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LT32" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ankrd28", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LT32", "locus": {} } ], "crossref": [ { "id": "100767224", "url": "https://www.ncbi.nlm.nih.gov/gene/100767224", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100767224", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767224", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LT32", "url": "https://www.orthodb.org/?gene=A0A8C2LT32", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7F1H6", "url": "https://www.orthodb.org/?gene=A0A9J7F1H6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24198", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24198", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24198:SF192", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24198:SF192", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13637", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13637", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003495347", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003495347", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LQR9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LQR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LQR9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LT32", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LT32", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LT32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LT32-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F1H6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1H6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F1H6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F1H6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRVCIVVLEEVEDDSPVFISKLPQENKFLHSPPSGNVLPSLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQILLKHSADVNARDKNWQTPLHIAAANKAVKCAESLVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGANVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYMLKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANIDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAASMDANPAIVDNHGYTALHWACYNGHETCVELLLEQDVFQKIDGNAFSPLHCAVINDNEGAAEMLIDTLGASIVNGTDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSSGKTPLMMAAENGQTNTVEMLVSSASADLTLQDKSKNTALHLACGKGHETSALLILEKITDRNLINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALILATMMPVSSSSPLSSLTFNAINRYTNTSKTVSFEALPIMRNEPSSYCSFNNIGGEQEYLYTDVDELNDSDSETY", "length": 1083, "header": "tr|A0A8C2LT32-1|A0A8C2LT32_CRIGR Isoform 1 of Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X1 OS=Cricetulus griseus OX=10029 GN=Ankrd28 PE=4 SV=1 CANONICAL=A0A8C2LT32-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LQR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LT32/entry#A0A8C2LQR9-1", "sequence": { "sequence": 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"length": 1053, "header": "tr|A0A8C2LQR9-1|A0A8C2LQR9_CRIGR Computationally mapped isoform of Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A OS=Cricetulus griseus OX=10029 GN=Ankrd28 PE=4 SV=1 CANONICAL=A0A8C2LT32-1" }, "locus": {} }, { "isoform_ac": "A0A8C2LT32-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LT32/entry#A0A8C2LT32-1", "sequence": { "sequence": "MSRVCIVVLEEVEDDSPVFISKLPQENKFLHSPPSGNVLPSLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQILLKHSADVNARDKNWQTPLHIAAANKAVKCAESLVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGANVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYMLKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANIDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAASMDANPAIVDNHGYTALHWACYNGHETCVELLLEQDVFQKIDGNAFSPLHCAVINDNEGAAEMLIDTLGASIVNGTDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSSGKTPLMMAAENGQTNTVEMLVSSASADLTLQDKSKNTALHLACGKGHETSALLILEKITDRNLINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALILATMMPVSSSSPLSSLTFNAINRYTNTSKTVSFEALPIMRNEPSSYCSFNNIGGEQEYLYTDVDELNDSDSETY", "length": 1083, "header": "tr|A0A8C2LT32-1|A0A8C2LT32_CRIGR Isoform 1 of Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X1 OS=Cricetulus griseus OX=10029 GN=Ankrd28 PE=4 SV=1 CANONICAL=A0A8C2LT32-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F1H6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LT32/entry#A0A9J7F1H6-1", "sequence": { "sequence": "MRRELLYMLLPILEMQKSLNCLFYLEAVQILLKHSADVNARDKNWQTPLHIAAANKAVKCAESLVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGANVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYMLKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANIDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGALLQSAASMDANPAIVDNHGYTALHWACYNGHETCVELLLEQDVFQKIDGNAFSPLHCAVINDNEGAAEMLIDTLGASIVNGTDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSSGKTPLMMAAENGQTNTVEMLVSSASADLTLQDKSKNTALHLACGKGHETSALLILEKITDRNLINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALILATMMPVSSSSPLSSLTFNAINRYTNTSKTVSFEALPIMRNEPSSYCSFNNIGGEQEYLYTDVDELNDSDSETY", "length": 991, "header": "tr|A0A9J7F1H6-1|A0A9J7F1H6_CRIGR Computationally mapped isoform of Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X2 OS=Cricetulus griseus OX=10029 GN=Ankrd28 PE=4 SV=1 CANONICAL=A0A8C2LT32-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LT32", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LT32" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LT32", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LT32" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100767224", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100767224", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LT32", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LT32" } ], "pmid": "" }, { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LT32", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LT32" } ], "pmid": "" }, { "name": "protein serine/threonine phosphatase complex", "id": "GO:0008287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008287", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LT32", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LT32" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LT32", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LT32" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein phosphatase regulator activity", "id": "GO:0019888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019888", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LT32", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LT32" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of focal 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LTA4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTA4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { 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"tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LTL2-1", "uniprot_ac": "A0A8C2LTL2", "uniprot_id": "A0A8C2LTL2_CRIGR", "mass": { "chemical_mass": 53317.0, "monoisotopic_mass": 53317.0 }, "refseq": { "ac": "XP_035298517", "name": "heat shock factor protein 4 isoform X5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298517" }, "gene_names": [ { "name": "Hsf4", "type": "recommended", "evidence": [ { "id": "A0A8C2LTL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTL2" } ] }, { "name": "Hsf4", "type": "synonym", "evidence": [ { "id": "XP_035298517", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298517" } ] } ], "protein_names": [ { "name": "Heat shock factor protein 4 isoform X5", "type": "synonym", "evidence": [ { "id": "A0A8C2LTL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTL2/entry#names_and_taxonomy" } ] }, { "name": "heat shock factor protein 4 isoform X5", "type": "synonym", "evidence": [ { "id": "XP_035298517", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298517" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035298517", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298517" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LTL2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTL2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Hsf4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTL2", "locus": {} } ], "crossref": [ { "id": "100758969", "url": "https://www.ncbi.nlm.nih.gov/gene/100758969", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000232", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000232", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100758969", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758969", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LTL2", "url": "https://www.orthodb.org/?gene=A0A8C2LTL2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GWI0", "url": "https://www.orthodb.org/?gene=A0A9J7GWI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015:SF213", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015:SF213", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00447", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00447", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035298517", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035298517", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LTL2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LTL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTL2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QFL7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QFL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QFL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QFL7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GWI0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GWI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GWI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GWI0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GY76", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GY76-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GY76-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLPQYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRKVPALRGDDTRWRPEDLGRLLGEVQALRGVQESTEARLQELRQQNEILWREVVTLRQSHSQQHRVIGKLIQCLFGPLQTGPSSTGTKRKLSLMLDEGSSCSAPAKFSACPLSGAFIQDPYFIQSPLPEATLGLSPHRARGPIISDIPEDAPSPEGHRLSPSSGGRRVKGLALLKEEPASPGGDGEAGLALAPNECDFCVTAPPPLPVAVVQAILEGKGSYSPEGPRSVQQPEPRGPREVPDRGTLGLDRGNRSPESLLPPMLLRPPPETVEPIAPMDVLGPSLQGREWTLMDLDMELSLMQPLAQERVEAELTVKELNSSGVGKDHTLGTPLLLDIPADLEGAALPVPGALTLYNAPESSASYLDPGANPSSP", "length": 492, "header": "tr|A0A8C2LTL2-1|A0A8C2LTL2_CRIGR Isoform 1 of Heat shock factor protein 4 isoform X5 OS=Cricetulus griseus OX=10029 GN=Hsf4 PE=3 SV=1 CANONICAL=A0A8C2LTL2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LTL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTL2/entry#A0A8C2LTL2-1", "sequence": { "sequence": "MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLPQYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRKVPALRGDDTRWRPEDLGRLLGEVQALRGVQESTEARLQELRQQNEILWREVVTLRQSHSQQHRVIGKLIQCLFGPLQTGPSSTGTKRKLSLMLDEGSSCSAPAKFSACPLSGAFIQDPYFIQSPLPEATLGLSPHRARGPIISDIPEDAPSPEGHRLSPSSGGRRVKGLALLKEEPASPGGDGEAGLALAPNECDFCVTAPPPLPVAVVQAILEGKGSYSPEGPRSVQQPEPRGPREVPDRGTLGLDRGNRSPESLLPPMLLRPPPETVEPIAPMDVLGPSLQGREWTLMDLDMELSLMQPLAQERVEAELTVKELNSSGVGKDHTLGTPLLLDIPADLEGAALPVPGALTLYNAPESSASYLDPGANPSSP", "length": 492, "header": "tr|A0A8C2LTL2-1|A0A8C2LTL2_CRIGR Isoform 1 of Heat shock factor protein 4 isoform X5 OS=Cricetulus griseus OX=10029 GN=Hsf4 PE=3 SV=1 CANONICAL=A0A8C2LTL2-1" }, "locus": {} }, { "isoform_ac": "A0A8C2QFL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTL2/entry#A0A8C2QFL7-1", "sequence": { "sequence": "MGPGGRPRHRPPHPLEPDGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRKVPALRGDDTRWRPEDLGRLLGEVQALRGVQESTEARLQELRQQNEILWREVVTLRQSHSQQHRVIGKLIQCLFGPLQTGPSSTGTKRKLSLMLDEGSSCSAPAKFSACPLSGAFIQDPYFIQSPLPEATLGLSPHRARGPIISDIPEDAPSPEGHRLSPSSGGRRVKGLALLKEEPASPGGDGEAGLALAPNECDFCVTAPPPLPVAVVQAILEGKGSYSPEGPRSVQQPEPRGPREVPDRGTLGLDRGNRSPESLLPPMLLRPPPETVEPIAPMDVLGPSLQGREWTLMDLDMELSLMQPLAQERVEAELTVKELNSSGVGKDHTLGTPLLLDIPADLEGAALPVPGALTLYNAPESSASYLDPGANPSSP", "length": 432, "header": "tr|A0A8C2QFL7-1|A0A8C2QFL7_CRIGR Computationally mapped isoform of Heat shock factor protein 4 isoform X7 OS=Cricetulus griseus OX=10029 GN=Hsf4 PE=4 SV=1 CANONICAL=A0A8C2LTL2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GWI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTL2/entry#A0A9J7GWI0-1", "sequence": { "sequence": "MASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRKVPALRGDDTRWRPEDLGRLLGEVQALRGVQESTEARLQELRQQNEILWREVVTLRQSHSQQHRVIGKLIQCLFGPLQTGPSSTGTKRKLSLMLDEGSSCSAPAKFSACPLSGAFIQDPYFIQSPLPEATLGLSPHRARGPIISDIPEDAPSPEGHRLSPSSGGRRVKGLALLKEEPASPGGDGEAGLALAPNECDFCVTAPPPLPVAVVQAILEGKGSYSPEGPRSVQQPEPRGPREVPDRGTLGLDRGNRSPESLLPPMLLRPPPETVEPIAPMDVLGPSLQGREWTLMDLDMELSLMQPLAQERVEAELTVKELNSSGVGKDHTLGTPLLLDIPADLEGAALPVPGALTLYNAPESSASYLDPGANPSSP", "length": 425, "header": "tr|A0A9J7GWI0-1|A0A9J7GWI0_CRIGR Computationally mapped isoform of Heat shock factor protein 4 isoform X4 OS=Cricetulus griseus OX=10029 GN=Hsf4 PE=3 SV=1 CANONICAL=A0A8C2LTL2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GY76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTL2/entry#A0A9J7GY76-1", "sequence": { "sequence": "MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLPQYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRKVPALRGDDTRWRPEDLGRLLGEVQALRGVQESTEARLQELRQQNEILWREVVTLRQSHSQQHRVIGKLIQCLFGPLQTGPSSTGTKRKLSLMLDEGSSCSAPAKFSACPLSGAFIQDPYFIQSPSTYSPSQRLPWASALTGPEGPSSLTSLKMLHLLKGTGFLPPVVAGAPPPLPVAVVQAILEGKGSYSPEGPRSVQQPEPRGPREVPDRGTLGLDRGNRSPESLLPPMLLRPPPETVEPIAPMDVLGPSLQGREWTLMDLDMELSLMQPLAQERVEAELTVKELNSSGVGKDHTLGTPLLLDIPADLEGAALPVPGALTLYNAPESSASYLDPGANPSSP", "length": 462, "header": "tr|A0A9J7GY76-1|A0A9J7GY76_CRIGR Computationally mapped isoform of Heat shock factor protein 4 isoform X6 OS=Cricetulus griseus OX=10029 GN=Hsf4 PE=3 SV=1 CANONICAL=A0A8C2LTL2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LTL2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTL2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027280836", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280836" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LTM9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTM9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "C7H16orf91", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTM9", "locus": {} } ], "crossref": [ { "id": "100772541", "url": "https://www.ncbi.nlm.nih.gov/gene/100772541", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR023248", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023248", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772541", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772541", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LTM9", "url": "https://www.orthodb.org/?gene=A0A8C2LTM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35268", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35268", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35268:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35268:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15013", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15013", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027280836", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280836", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LTM9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LTM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTM9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRGVLCSRTAGAVRALRLVGWTSRSLHPPLHGGSPAQPTDREEEEEEDLNHPLQFSSSKATPIRWTVEHSLGKNQRRPWWKVLPVTITLTVLILWCYLRQETSTDEWLREVMGEVEEEEPDGRLEDPEAPAFYGART", "length": 137, "header": "tr|A0A8C2LTM9-1|A0A8C2LTM9_CRIGR Isoform 1 of Protein CCSMST1 OS=Cricetulus griseus OX=10029 GN=C7H16orf91 PE=3 SV=1 CANONICAL=A0A8C2LTM9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LTM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTM9/entry#A0A8C2LTM9-1", "sequence": { "sequence": "MRGVLCSRTAGAVRALRLVGWTSRSLHPPLHGGSPAQPTDREEEEEEDLNHPLQFSSSKATPIRWTVEHSLGKNQRRPWWKVLPVTITLTVLILWCYLRQETSTDEWLREVMGEVEEEEPDGRLEDPEAPAFYGART", "length": 137, "header": "tr|A0A8C2LTM9-1|A0A8C2LTM9_CRIGR Isoform 1 of Protein CCSMST1 OS=Cricetulus griseus OX=10029 GN=C7H16orf91 PE=3 SV=1 CANONICAL=A0A8C2LTM9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LTQ8-1", "uniprot_ac": "A0A8C2LTQ8", "uniprot_id": "A0A8C2LTQ8_CRIGR", "mass": { "chemical_mass": 60373.0, "monoisotopic_mass": 60373.0 }, "refseq": { "ac": "XP_035301996", "name": "protein FAM178B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301996" }, "gene_names": [ { "name": "Fam178b", "type": "recommended", "evidence": [ { "id": "A0A8C2LTQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTQ8" } ] }, { "name": "Fam178b", "type": "synonym", "evidence": [ { "id": "XP_035301996", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301996" } ] } ], "protein_names": [ { "name": "Protein FAM178B isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8C2LTQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTQ8/entry#names_and_taxonomy" } ] }, { "name": "protein FAM178B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_035301996", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301996" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613687.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035301996", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301996" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LTQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTQ8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Fam178b", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTQ8", "locus": {} } ], "crossref": [ { "id": "100768604", "url": "https://www.ncbi.nlm.nih.gov/gene/100768604", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "QAMHRTR", "url": "https://omabrowser.org/oma/group/QAMHRTR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR16046", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16046", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16046:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16046:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14816", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14816", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035301996", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301996", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LTQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LTQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQMPRDSFPTDWSPPPVEFLNKNRKVLQACRRLHEDWEEEAPDSDQKLGLTSLEELFWNMAGPSQQAVTPKVSYGGSECYVNNLDYLLQEKRMLVEKFSISLQVISPVHPGETVFLPRRQPLPCILDSSSLKPHSQLEELFLRSPLPQQLSFLHKGLLSNLYLHASDYPRPLLQWLFKLLTWPPETSSRAFSLLWDLSIDGLFRQPDEDMRLWCPSLQEVKEVFRSLGAYNPALYPQGPFRHSTRVLESEASLGWWEPHNSTQEVALDIKLSYIYRFLILCFLVQPRSYTDANILGLMELLCRAGLDVGLRLLPKTDLQQLLLLLLENIQEWPGKLQALCCTLSWVSDHHHNLLALVQFFLDVTPRARQLRSQLSLTVIARMLGQQEALPLWGEKSQLALLSQLLSLMRPSSLRQCLGAETLPSCQGQEPKATAELDHKVCYLCHSLLTLAGVVVSSQDITPDQWGELQLLCMQLDRHISTHIRESPQAMHRTKLKDLATQTYIRWQDLLAHCQPQGQYFSPWKDI", "length": 526, "header": "tr|A0A8C2LTQ8-1|A0A8C2LTQ8_CRIGR Isoform 1 of Protein FAM178B isoform X1 OS=Cricetulus griseus OX=10029 GN=Fam178b PE=3 SV=1 CANONICAL=A0A8C2LTQ8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LTQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTQ8/entry#A0A8C2LTQ8-1", "sequence": { "sequence": "MQMPRDSFPTDWSPPPVEFLNKNRKVLQACRRLHEDWEEEAPDSDQKLGLTSLEELFWNMAGPSQQAVTPKVSYGGSECYVNNLDYLLQEKRMLVEKFSISLQVISPVHPGETVFLPRRQPLPCILDSSSLKPHSQLEELFLRSPLPQQLSFLHKGLLSNLYLHASDYPRPLLQWLFKLLTWPPETSSRAFSLLWDLSIDGLFRQPDEDMRLWCPSLQEVKEVFRSLGAYNPALYPQGPFRHSTRVLESEASLGWWEPHNSTQEVALDIKLSYIYRFLILCFLVQPRSYTDANILGLMELLCRAGLDVGLRLLPKTDLQQLLLLLLENIQEWPGKLQALCCTLSWVSDHHHNLLALVQFFLDVTPRARQLRSQLSLTVIARMLGQQEALPLWGEKSQLALLSQLLSLMRPSSLRQCLGAETLPSCQGQEPKATAELDHKVCYLCHSLLTLAGVVVSSQDITPDQWGELQLLCMQLDRHISTHIRESPQAMHRTKLKDLATQTYIRWQDLLAHCQPQGQYFSPWKDI", "length": 526, "header": "tr|A0A8C2LTQ8-1|A0A8C2LTQ8_CRIGR Isoform 1 of Protein FAM178B isoform X1 OS=Cricetulus griseus OX=10029 GN=Fam178b PE=3 SV=1 CANONICAL=A0A8C2LTQ8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 69, "start_aa": "Thr", "end_pos": 69, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr69", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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:: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035309361", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309361" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LTT8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Slc35f4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT8", "locus": {} } ], "crossref": [ { "id": "100755204", "url": "https://www.ncbi.nlm.nih.gov/gene/100755204", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000620", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000620", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026505", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026505", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755204", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755204", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LTT8", "url": "https://www.orthodb.org/?gene=A0A8C2LTT8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19346", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19346", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19346:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19346:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00892", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00892", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035309361", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035309361", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LTT8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LTT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDVKAAPNGVATIEDRILRITGYYGYYPGYSSQKSTSRSSVSRCKPGSNCPSSHSSISRQLSPLSVTEDSSAPILELQSRGSSGVCGHRVERQSRSGDDGTQTHPESNSQENRLKARCLSCMSVVLKAIWGLLIILSVSSSWVGTTQIVKITYKNFYCPFFMTWFSTNWNIMFFPVYYSGHLATAQEKQSPMKKFRECSRIFGEDGLTLKLFLKRTAPFSILWTLTNYLYLLALKKLTATDVSALFCCNKAFVFLLSWIVLKDRFMGVRIVAAIMAITGIVMMAYADNFHADSIIGVAFAVGSASTSALYKVLFKMFLGSANFGEAAHFVSTLAFFNLIFISFTPIILYFTKVEHWSSFAALPWGCLCGMAGLWLAFNILVNVGVLLTYPILISIGTVLSVPGNAAVDLLKQEVIFNVVRLAATIIICIGFLLMLLPEEWDEITLRFINSLKEKKSEEHVEDLADVSVHLRSRSRVNGTVSIPLA", "length": 485, "header": "tr|A0A8C2LTT8-1|A0A8C2LTT8_CRIGR Isoform 1 of Solute carrier family 35 member F4 isoform X2 OS=Cricetulus griseus OX=10029 GN=Slc35f4 PE=4 SV=1 CANONICAL=A0A8C2LTT8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LTT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTT8/entry#A0A8C2LTT8-1", "sequence": { "sequence": "MDVKAAPNGVATIEDRILRITGYYGYYPGYSSQKSTSRSSVSRCKPGSNCPSSHSSISRQLSPLSVTEDSSAPILELQSRGSSGVCGHRVERQSRSGDDGTQTHPESNSQENRLKARCLSCMSVVLKAIWGLLIILSVSSSWVGTTQIVKITYKNFYCPFFMTWFSTNWNIMFFPVYYSGHLATAQEKQSPMKKFRECSRIFGEDGLTLKLFLKRTAPFSILWTLTNYLYLLALKKLTATDVSALFCCNKAFVFLLSWIVLKDRFMGVRIVAAIMAITGIVMMAYADNFHADSIIGVAFAVGSASTSALYKVLFKMFLGSANFGEAAHFVSTLAFFNLIFISFTPIILYFTKVEHWSSFAALPWGCLCGMAGLWLAFNILVNVGVLLTYPILISIGTVLSVPGNAAVDLLKQEVIFNVVRLAATIIICIGFLLMLLPEEWDEITLRFINSLKEKKSEEHVEDLADVSVHLRSRSRVNGTVSIPLA", "length": 485, "header": "tr|A0A8C2LTT8-1|A0A8C2LTT8_CRIGR Isoform 1 of Solute carrier family 35 member F4 isoform X2 OS=Cricetulus griseus OX=10029 GN=Slc35f4 PE=4 SV=1 CANONICAL=A0A8C2LTT8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NW_003613589.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NC_048600.1) and transcript sequence (IACG01110749.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304219", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304219" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LTY1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTY1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Prcd", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTY1", "locus": {} } ], "crossref": [ { "id": "100755980", "url": "https://www.ncbi.nlm.nih.gov/gene/100755980", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755980", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755980", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CRRRFAN", "url": "https://omabrowser.org/oma/group/CRRRFAN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LTY1", "url": "https://www.orthodb.org/?gene=A0A8C2LTY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR38501", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38501", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR38501:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38501:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15201", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15201", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304219", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304219", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LTY1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LTY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTY1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCTTLFLLSLAMLWRRRFGNRVEPEPSTVDGAAVGSADTDLQASGREKEPVR", "length": 52, "header": "tr|A0A8C2LTY1-1|A0A8C2LTY1_CRIGR Isoform 1 of Photoreceptor disk component PRCD isoform X2 OS=Cricetulus griseus OX=10029 GN=Prcd PE=4 SV=1 CANONICAL=A0A8C2LTY1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LTY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTY1/entry#A0A8C2LTY1-1", "sequence": { "sequence": "MCTTLFLLSLAMLWRRRFGNRVEPEPSTVDGAAVGSADTDLQASGREKEPVR", "length": 52, "header": "tr|A0A8C2LTY1-1|A0A8C2LTY1_CRIGR Isoform 1 of Photoreceptor disk component PRCD isoform X2 OS=Cricetulus griseus OX=10029 GN=Prcd PE=4 SV=1 CANONICAL=A0A8C2LTY1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"yes" } }, { "uniprot_canonical_ac": "A0A8C2LTY8-1", "uniprot_ac": "A0A8C2LTY8", "uniprot_id": "A0A8C2LTY8_CRIGR", "mass": { "chemical_mass": 58969.0, "monoisotopic_mass": 58969.0 }, "refseq": { "ac": "XP_003515039", "name": "spermatogenesis-associated serine-rich protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003515039" }, "gene_names": [ { "name": "Spats2", "type": "recommended", "evidence": [ { "id": "A0A8C2LTY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTY8" } ] }, { "name": "Spats2", "type": "synonym", "evidence": [ { "id": "XP_003515039", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003515039" } ] } ], "protein_names": [ { "name": "Spermatogenesis-associated serine-rich protein 2 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A8C2LTY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTY8/entry#names_and_taxonomy" } ] }, { "name": "spermatogenesis-associated serine-rich protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003515039", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003515039" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 1612 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003617203.1) and transcript sequence (IACG01050548.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003515039.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003515039", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003515039" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LTY8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTY8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Spats2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTY8", "locus": {} } ], "crossref": [ { "id": "100762195", "url": "https://www.ncbi.nlm.nih.gov/gene/100762195", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009816", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009816", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762195", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762195", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LTY8", "url": "https://www.orthodb.org/?gene=A0A8C2LTY8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15623", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15623", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15623:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15623:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07139", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07139", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003515039", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003515039", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LTY8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LTY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JA28", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JA28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JA28-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JA28-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSRKQSQKDSSGFIFDLQSNTVLAQGGTFENMKEKINAVRAIVPNKSNNEIILVLQHFDNCVDKTVQAFMEGSASDVLKEWIVTGKKKNKKKKSKPKPASEANSNAPDSSKSVPIQEEQPASSEKGGINGYHVNGAINDAESVDSLSEGLETLSIDARELEDPEFATPDTLDRTGSVLENGVSDFEPKSLTTHSIPNAQQSRNAAKSLSRATTGAQVSNLGMENAPLSSTNKRLGSNIEKSVKDLQRCTVSLARYRVVVKEEMDASIKKMKQAFAELQSCLMDREVALLAEMDKVKAEAMEILLSRQKKAEVLKKMTDVAVRMSEEQLIELRADIKHFVSERKYDEDLGRVARFTCDVETLKQSIDSFGQVSHPKNSYSTRSRCSSVVSVSLSGPGDVSAASSSPCASAPSLPGANKRNCAPGETSAAMTNSSDKPCQAHQEVFPGNRRGGQGYRPQNQKTTDPTNQGRHDSAGRYRNSSWYSSGSRYQSTSPQAPGNASEWSQAYSAGTNGTGASMAPSPPKPSFKKGLPQRKPRTSQAAAVNS", "length": 545, "header": "tr|A0A8C2LTY8-1|A0A8C2LTY8_CRIGR Isoform 1 of Spermatogenesis-associated serine-rich protein 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Spats2 PE=3 SV=1 CANONICAL=A0A8C2LTY8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LTY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTY8/entry#A0A8C2LTY8-1", "sequence": { "sequence": "MSRKQSQKDSSGFIFDLQSNTVLAQGGTFENMKEKINAVRAIVPNKSNNEIILVLQHFDNCVDKTVQAFMEGSASDVLKEWIVTGKKKNKKKKSKPKPASEANSNAPDSSKSVPIQEEQPASSEKGGINGYHVNGAINDAESVDSLSEGLETLSIDARELEDPEFATPDTLDRTGSVLENGVSDFEPKSLTTHSIPNAQQSRNAAKSLSRATTGAQVSNLGMENAPLSSTNKRLGSNIEKSVKDLQRCTVSLARYRVVVKEEMDASIKKMKQAFAELQSCLMDREVALLAEMDKVKAEAMEILLSRQKKAEVLKKMTDVAVRMSEEQLIELRADIKHFVSERKYDEDLGRVARFTCDVETLKQSIDSFGQVSHPKNSYSTRSRCSSVVSVSLSGPGDVSAASSSPCASAPSLPGANKRNCAPGETSAAMTNSSDKPCQAHQEVFPGNRRGGQGYRPQNQKTTDPTNQGRHDSAGRYRNSSWYSSGSRYQSTSPQAPGNASEWSQAYSAGTNGTGASMAPSPPKPSFKKGLPQRKPRTSQAAAVNS", "length": 545, "header": "tr|A0A8C2LTY8-1|A0A8C2LTY8_CRIGR Isoform 1 of Spermatogenesis-associated serine-rich protein 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Spats2 PE=3 SV=1 CANONICAL=A0A8C2LTY8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JA28-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTY8/entry#A0A9J7JA28-1", "sequence": { "sequence": "MKEKINAVRAIVPNKSNNEIILVLQHFDNCVDKTVQAFMEGSASDVLKEWIVTGKKKNKKKKSKPKPASEANSNAPDSSKSVPIQEEQPASSEKGGINGYHVNGAINDAESVDSLSEGLETLSIDARELEDPEFATPDTLDRTGSVLENGVSDFEPKSLTTHSIPNAQQSRNAAKSLSRATTGAQVSNLGMENAPLSSTNKRLGSNIEKSVKDLQRCTVSLARYRVVVKEEMDASIKKMKQAFAELQSCLMDREVALLAEMDKVKAEAMEILLSRQKKAEVLKKMTDVAVRMSEEQLIELRADIKHFVSERKYDEDLGRVARFTCDVETLKQSIDSFGQVSHPKNSYSTRSRCSSVVSVSLSGPGDVSAASSSPCASAPSLPGANKRNCAPGETSAAMTNSSDKPCQAHQEVFPGNRRGGQGYRPQNQKTTDPTNQGRHDSAGRYRNSSWYSSGSRYQSTSPQAPGNASEWSQAYSAGTNGTGASMAPSPPKPSFKKGLPQRKPRTSQAAAVNS", "length": 514, "header": "tr|A0A9J7JA28-1|A0A9J7JA28_CRIGR Computationally mapped isoform of Spermatogenesis-associated serine-rich protein 2 isoform X3 OS=Cricetulus griseus OX=10029 GN=Spats2 PE=3 SV=1 CANONICAL=A0A8C2LTY8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LTY8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTY8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LTY8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTY8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762195", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762195", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LTY8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTY8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LTY8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LTY8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 431, "end_pos": 433, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" }, { "start_pos": 478, "end_pos": 480, "annotation": "n_glycosylation_sequon" }, { "start_pos": 498, "end_pos": 500, "annotation": "n_glycosylation_sequon" }, { "start_pos": 511, "end_pos": 513, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 431, "end_pos": 433 }, { "start_pos": 45, "end_pos": 47 }, { "start_pos": 478, "end_pos": 480 }, { "start_pos": 498, "end_pos": 500 }, { "start_pos": 511, "end_pos": 513 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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This record is derived from a genomic sequence (NC_048601.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035304694", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304694" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LU09", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LU09" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tspan11", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LU09", "locus": {} } ], "crossref": [ { "id": "cd03155", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03155", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100770678", "url": "https://www.ncbi.nlm.nih.gov/gene/100770678", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000301", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000301", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008952", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008952", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018499", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018499", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100770678", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770678", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HCGQRAH", "url": "https://omabrowser.org/oma/group/HCGQRAH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LU09", "url": "https://www.orthodb.org/?gene=A0A8C2LU09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19282", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19282", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19282:SF198", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19282:SF198", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00335", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00335", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035304694", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035304694", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LU09", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LU09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LU09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LU09-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAYCKTEQDDWLLAHLKYLLFIFNFFFWVGGAAVMAVGIWTLVEKSGYLSILASSTFPASAYILIFAGALVVTTGFLGFGAIIREQKGCLSMYFCLLLVIFLVELVAGVLAHVYYQRLSDELRQHLNSTLTEHYGQPRAAEITASVDRLQQDFKCCGSNSSADWQHSTYILSREAQGRRVPDSCCKTVVARCGQRAHPSNIYKVEGGCMAKLEQFLADHLLLMGAVGIGVACLQICGMVLTCCLHRRLQQHFY", "length": 253, "header": "tr|A0A8C2LU09-1|A0A8C2LU09_CRIGR Isoform 1 of Tetraspanin OS=Cricetulus griseus OX=10029 GN=Tspan11 PE=3 SV=1 CANONICAL=A0A8C2LU09-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LU09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LU09/entry#A0A8C2LU09-1", "sequence": { "sequence": "MAYCKTEQDDWLLAHLKYLLFIFNFFFWVGGAAVMAVGIWTLVEKSGYLSILASSTFPASAYILIFAGALVVTTGFLGFGAIIREQKGCLSMYFCLLLVIFLVELVAGVLAHVYYQRLSDELRQHLNSTLTEHYGQPRAAEITASVDRLQQDFKCCGSNSSADWQHSTYILSREAQGRRVPDSCCKTVVARCGQRAHPSNIYKVEGGCMAKLEQFLADHLLLMGAVGIGVACLQICGMVLTCCLHRRLQQHFY", "length": 253, "header": "tr|A0A8C2LU09-1|A0A8C2LU09_CRIGR Isoform 1 of Tetraspanin OS=Cricetulus griseus OX=10029 GN=Tspan11 PE=3 SV=1 CANONICAL=A0A8C2LU09-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NW_003613633.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035293013", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293013" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LU95", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LU95" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Fam217b", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LU95", "locus": {} } ], "crossref": [ { "id": "100771062", "url": "https://www.ncbi.nlm.nih.gov/gene/100771062", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771062", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771062", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RPSYYAF", "url": "https://omabrowser.org/oma/group/RPSYYAF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LU95", "url": "https://www.orthodb.org/?gene=A0A8C2LU95", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22145", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22145", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22145:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22145:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035293013", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293013", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LU95", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LU95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LU95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LU95-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDFHQKSSMNAGSSWNQEQHSKTSSGKRQSRSQGLQASSHLGSSLLGISQPAADKLIRTISTEGRQDQERTVLSSRCQAASGSKLFLEFQSMKIIKDGTDEDSASDLSDSERVAIPPSPFTPPDLNLRAEEIDPVSFSLYPDPRLAEPEHCYPDFLPPPFSSWDLQDMAVAMNTECRSEALPRATGFLGKYIDRLLQLEWLQVQTVQCEKARAAKARPPGASGMLKSPRRGKLLTSVLSKPLLSPEGIPKPGPSRKKGFHHEEIHPSYYTFETSPRSVDGPGRPRLCSQKQAPEVRMEKKKKSSKAPKLHLCAPPCAEGSPALEANGNIRIPTKSAVLDPRDSCGASRSQAHLDLKKKGNANNYGLTSSSREKKLKTNGGKQSMYKLK", "length": 389, "header": "tr|A0A8C2LU95-1|A0A8C2LU95_CRIGR Isoform 1 of Protein FAM217B OS=Cricetulus griseus OX=10029 GN=Fam217b PE=4 SV=1 CANONICAL=A0A8C2LU95-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LU95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LU95/entry#A0A8C2LU95-1", "sequence": { "sequence": "MSDFHQKSSMNAGSSWNQEQHSKTSSGKRQSRSQGLQASSHLGSSLLGISQPAADKLIRTISTEGRQDQERTVLSSRCQAASGSKLFLEFQSMKIIKDGTDEDSASDLSDSERVAIPPSPFTPPDLNLRAEEIDPVSFSLYPDPRLAEPEHCYPDFLPPPFSSWDLQDMAVAMNTECRSEALPRATGFLGKYIDRLLQLEWLQVQTVQCEKARAAKARPPGASGMLKSPRRGKLLTSVLSKPLLSPEGIPKPGPSRKKGFHHEEIHPSYYTFETSPRSVDGPGRPRLCSQKQAPEVRMEKKKKSSKAPKLHLCAPPCAEGSPALEANGNIRIPTKSAVLDPRDSCGASRSQAHLDLKKKGNANNYGLTSSSREKKLKTNGGKQSMYKLK", "length": 389, "header": "tr|A0A8C2LU95-1|A0A8C2LU95_CRIGR Isoform 1 of Protein FAM217B OS=Cricetulus griseus OX=10029 GN=Fam217b PE=4 SV=1 CANONICAL=A0A8C2LU95-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027268916", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268916" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LUE3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUE3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Gnb1l", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUE3", "locus": {} } ], "crossref": [ { "id": "100773508", "url": "https://www.ncbi.nlm.nih.gov/gene/100773508", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773508", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773508", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YQRQSMQ", "url": "https://omabrowser.org/oma/group/YQRQSMQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LUE3", "url": "https://www.orthodb.org/?gene=A0A8C2LUE3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19854", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19854", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19854:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19854:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027268916", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027268916", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LUE3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LUE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUE3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAPFPPPPGPRFVLRGTQSPVNTLHFCPASQALGNPLLFSGSQSGLVHIWSLQTRRTVAALNGHKGQGVTWLKTLPQGHQLLSQGRDLRLCLWDLAEGRNTIMDTVQLDSVGFCKSSVLARGQLCWMLAVPGKGSDEVQILEMPSKTSVCTLKPEADAKPGMPMCLGLWQTNSSPRPLLLAGYEDGSVTLWDILERKVCSRIACHEEPVMGLDFDSQKAKGVSGSAGKVLAVWSLDGQQSLQVYKTHELTNPGIAEVTIRPDHKILATAGWDHRIRVFHWRTMKPLAVLAFHSASVYCVAFATDGLLAAGSKDQRISIWSLYPCS", "length": 326, "header": "tr|A0A8C2LUE3-1|A0A8C2LUE3_CRIGR Isoform 1 of Guanine nucleotide-binding protein subunit beta-like protein 1 isoform X4 OS=Cricetulus griseus OX=10029 GN=Gnb1l PE=4 SV=1 CANONICAL=A0A8C2LUE3-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LUE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUE3/entry#A0A8C2LUE3-1", "sequence": { "sequence": "MAAPFPPPPGPRFVLRGTQSPVNTLHFCPASQALGNPLLFSGSQSGLVHIWSLQTRRTVAALNGHKGQGVTWLKTLPQGHQLLSQGRDLRLCLWDLAEGRNTIMDTVQLDSVGFCKSSVLARGQLCWMLAVPGKGSDEVQILEMPSKTSVCTLKPEADAKPGMPMCLGLWQTNSSPRPLLLAGYEDGSVTLWDILERKVCSRIACHEEPVMGLDFDSQKAKGVSGSAGKVLAVWSLDGQQSLQVYKTHELTNPGIAEVTIRPDHKILATAGWDHRIRVFHWRTMKPLAVLAFHSASVYCVAFATDGLLAAGSKDQRISIWSLYPCS", "length": 326, "header": "tr|A0A8C2LUE3-1|A0A8C2LUE3_CRIGR Isoform 1 of Guanine nucleotide-binding protein subunit beta-like protein 1 isoform X4 OS=Cricetulus griseus OX=10029 GN=Gnb1l PE=4 SV=1 CANONICAL=A0A8C2LUE3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LUE3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUE3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LUE3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUE3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773508", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773508", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1UT29-1", "protein_name": "G protein subunit beta 1 like", "gene_name": "GNB1L", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MADLPLPPPDPQFVLRGTQSAVHALHFCGGAQGQGCPLLLSGSLRGLVHIWSLQTRRVVATLDGHGGQCVTWLQTLPQGPQLLSQGRDLKLCLWDLAEGRNTVVDSVHLESVGFCRGSILAGGQPRWMLAVPGSGSDEVQILEMPSKTSVCSLKPEAGARPGMPMCLQLWQANSSPRPLLLAGYEDGSVALWDVSEQKVCSRIACHTEPVMGLDVDSQKARGVSGSAEKALAVWSVDEQQALQVRRTHQLTNPGIADIKIRPDRKILATAGWDHRVRVFLWQTMKPLAVLAFHSATVHCVAFAADSLLAAGSGDHRISIWSLYPHT", "length": 326 }, "evidence": [ { "id": "A0A8C2LUE3", "url": "https://omabrowser.org/oma/group/A0A8C2LUE3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0ZY84-1", "protein_name": "G protein subunit beta 1 like", "gene_name": "GNB1L", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAQPPPDPHFVLRGTGAAVHALHFSCGGGEPDIPVLFSGSENGFIHVWNLKTHRVDAALDGHGRKSVCGLKTMDGKERLLSQGRDQRICLWDLAEGRTSVTDSVFTENVGFCRCSLLKVAEGRWLMATAAKALEEVQVLELPSKTSVCTLKPEVGAKLGMPMCLKLWQGSCGSQPSLLAGYEDGSVLLWNLSTGKVLSQLICHQEPVMSLDFDSEKAKGISGSSEKVLSIWSLNEQQNLQKTHRLVNAGISDITIRPDKKILATAGWDHRIRIFGWKKLKPLAVLDYHTATVHSVSFSDHKSPSDRLLAAGAKDHRISIWSIYTQT", "length": 326 }, "evidence": [ { "id": "A0A8C2LUE3", "url": "https://omabrowser.org/oma/group/A0A8C2LUE3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4A2F0-1", "protein_name": "G protein subunit beta 1 like", "gene_name": "Gnb1l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAPFPPPPSPRFVLRGTQSAVNTLHFCPAPGAAENPLLFSGSQNGLVHIWSLQTRRIVATLNGHGGQGVTWLKTLPQGQQLLSQGRDPRLCLWDLAEGRNTVMDSVQLDSVGFCKSSILVRGQLCWMLAVPGKGSDEVQILEMPSKTSVCTLKPEADAKPGMPMCLGLWQTNSSLRPLLLAGYEDGSVTLWDVSERKVCSQITCHEEPVMGLDFDSQKAKGVSGSAGKVLAVWSLDDQQSLQVKKTHELINPGIAEVTLRPDHRLFATAGWDHRIRVFHWRTIKPLAVLAFHSAPVHCVAFAADGLLAAGSKDQRISVWSLYPCP", "length": 326 }, "evidence": [ { "id": "A0A8C2LUE3", "url": "https://omabrowser.org/oma/group/A0A8C2LUE3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3MV14-1", "protein_name": "Protein DECREASED SIZE EXCLUSION LIMIT 1", "gene_name": "DSE1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSKRPPPDPVAVLRGHRHSVMDVSFHPSKSLLFTGSADGELRIWDTIQHRAVSSAWAHSRANGVLAVAASPWLGEDKIISQGRDGTVKCWDIEDGGLSRDPLLILETCAYHFCKFSLVKKPKNSLQEAESHSRGCDEQDGGDTCNVQIADDSERSEEDSGLLQDKDHAEGTTFVAVVGEQPTEVEIWDLNTGDKIIQLPQSSPDESPNASTKGRGMCMAVQLFCPPESQGFLHVLAGYEDGSILLWDIRNAKIPLTSVKFHSEPVLSLSVASSCDGGISGGADDKIVMYNLNHSTGSCTIRKEITLERPGVSGTSIRVDGKIAATAGWDHRIRVYNYRKGNALAILKYHRATCNAVSYSPDCELMASASEDATVALWKLYPPHKSL", "length": 386 }, "evidence": [ { "id": "A0A8C2LUE3", "url": "https://omabrowser.org/oma/group/A0A8C2LUE3/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q54HW5-1", "protein_name": "Guanine nucleotide-binding protein subunit beta-like protein 1 homolog", "gene_name": "gnb1l", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNKEASNNNNSAPDPYYILRGHKFNVNSVLFDKVNPNLLYSGSGDGELKLWNIEEKKCISTQIAHSEGIGGGVLSLQWLSNDNNNENNNNNDEICGNILSQGRDGVIKIWSIIDNCTFKNTYRLETNSLSLGKCSSLSSNLLSISGSAIDPTSSTSQVEIWDLKNKQVINKLKPNNQQLFEKLGLPMSLKLYYENENNDNSNQSNDQIRLCTGYENGELLIWDLRNTSIPLVSSKLHNEPILSFALSNNSTKGISGSGDTNIIEFNINYESKQFNITKTHKLNNGGISEIKIRNDEKIYATAGWDKRIRIFNFKKQTPLAILKYHTESVYSIDFNSNNILASGSKDCKIALWDIYTTKK", "length": 359 }, "evidence": [ { "id": "A0A8C2LUE3", "url": "https://omabrowser.org/oma/group/A0A8C2LUE3/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9BYB4-1", "protein_name": "Guanine nucleotide-binding protein subunit beta-like protein 1", "gene_name": "GNB1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTAPCPPPPPDPQFVLRGTQSPVHALHFCEGAQAQGRPLLFSGSQSGLVHIWSLQTRRAVTTLDGHGGQCVTWLQTLPQGRQLLSQGRDLKLCLWDLAEGRSAVVDSVCLESVGFCRSSILAGGQPRWTLAVPGRGSDEVQILEMPSKTSVCALKPKADAKLGMPMCLRLWQADCSSRPLLLAGYEDGSVVLWDVSEQKVCSRIACHEEPVMDLDFDSQKARGISGSAGKALAVWSLDWQQALQVRGTHELTNPGIAEVTIRPDRKILATAGWDHRIRVFHWRTMQPLAVLAFHSAAVQCVAFTADGLLAAGSKDQRISLWSLYPRA", "length": 327 }, "evidence": [ { "id": "A0A8C2LUE3", "url": "https://omabrowser.org/oma/group/A0A8C2LUE3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9EQ15-1", "protein_name": "Guanine nucleotide-binding protein subunit beta-like protein 1", "gene_name": "Gnb1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAALFPPPPGPRFVLRGTQSAVNTLHFCPPSQAAGNPLLFSGSQNGLVHIWSLQTRRIVTTLNGHGGQGVIWLKTLPQGHQLLSQGRDLRLCLWDLEEGRNTIMDSVQLDSVGFCRGSILVRGQQCWMLAVPGKGSDEVQILEMPSKTSVCTLKPEADARPGMPMCLGLWQTNSSLRPLLLAGYEDGSVTLWDISERKVCSQITCHEEPVMGLDFDSQKAKGISGSAGKVLAVWSLDDQQSLQVKKTHELTNPGIAEVTIRPDHKILATAGWDHRIRVFHWRTMKPLAVLAFHSAPVYCVAFAADGLLAAGSKDQRISIWSLYPCP", "length": 326 }, "evidence": [ { "id": "A0A8C2LUE3", "url": "https://omabrowser.org/oma/group/A0A8C2LUE3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LUE3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUE3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LUE3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUE3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA damage checkpoint signaling", "id": "GO:0000077", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000077", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LUE3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUE3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 173, "end_pos": 175, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 173, "end_pos": 175 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LUE9-1", "uniprot_ac": "A0A8C2LUE9", "uniprot_id": "A0A8C2LUE9_CRIGR", "mass": { "chemical_mass": 10257.0, "monoisotopic_mass": 10257.0 }, "refseq": { "ac": "XP_035307594", "name": "late cornified envelope protein 3D-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307594" }, "gene_names": [ { "name": "LOC100757137", "type": "recommended", "evidence": [ { "id": "A0A8C2LUE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUE9" } ] }, { "name": "LOC100757137", "type": "synonym", "evidence": [ { "id": "XP_035307594", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307594" } ] } ], "protein_names": [ { "name": "Late cornified envelope protein 3D-like", "type": "synonym", "evidence": [ { "id": "A0A8C2LUE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUE9/entry#names_and_taxonomy" } ] }, { "name": "late cornified envelope protein 3D-like", "type": "synonym", "evidence": [ { "id": "XP_035307594", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307594" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. 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] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 21, "end_pos": 23, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LUG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUG5" }, { "id": "PF00061", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00061" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Lipocalin/cytosolic fatty-acid binding", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 168, "start_aa": "Asn", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], 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This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027265577.1. 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"MPKLVKNLLGEMPLWVCQSCRKSMEEDERQTGREHAVAISLSHTSCKSQSCGGDSHSSSSSSSSSSSSSSSSCHGNSGDWDPSSFLSAHKLSGLWNSPHSSGAVPGGSLGSPPAIPGEAFPVSEHHQHSDLTAPPNSPTGHPPHPASLVPSHPGSFSSPPHPHLLPTTPAAPCPAQASECPVAAATATHPPGPCQSPHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCGGPLLPPSSSQPLPSTHSRDPGCKGHKFAHSGLACEADEGLGEEEDSSSERSSCTSSSTHPRDGKFCDCCYCEFFGHNAPPAAPTSRNYTEIREKLRSRLTRRKEELPMKGGTLGGIPGEPAVDHRDVDELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKARLATEALKQVNRVSGSQSPRPARERLLEWPDQELDRVNSFLSSRLQEIKSTVKDSLCASFSTCELDMESSGFQEGTSEPQPQTPTPSDLNGSSEQQPDINLDLSPLTLGSLQSHSLQAPSEPVAAWAERRDPRPPWTETRGPPPGVPENGLVRRLNTVPNLSRVIWVKTPKPGNPNSEQSSKEVPSCKQELSEPVATGGKPRKSKRQGSQVKKTEAGLAPWPPANLEAPSAKSQTSSPKQPGKGPEPAKVGNCAEPGEGSRGSRPGPSWADSPKIEKKGSSWQNWPSEAKARTQEQESVQTPGPAKPQSLSQGKGRSRRSRKQEKSASSLDDVFLPKDMDGVEMDETDREVEYFKRFCLDSAKQTRQKVAVNWTNFSLKKTTPSTAH", "length": 779, "header": "tr|A0A8C2LUI4-1|A0A8C2LUI4_CRIGR Isoform 1 of Protein FAM193B isoform X1 OS=Cricetulus griseus OX=10029 GN=Fam193b PE=3 SV=1 CANONICAL=A0A8C2LUI4-1" }, "isoforms": [ { "isoform_ac": 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OS=Cricetulus griseus OX=10029 GN=Fam193b PE=3 SV=1 CANONICAL=A0A8C2LUI4-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GU77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUI4/entry#A0A9J7GU77-1", "sequence": { "sequence": "MQRPDEDEAWRKMRLALQTLHRAAGDSGRLVQPEGMALDSLLVESLELCIRDPGCKGHKFAHSGLACEADEGLGEEEDSSSERSSCTSSSTHPRDGKFCDCCYCEFFGHNAPPAAPTSRNYTEIREKLRSRLTRRKEELPMKGGTLGGIPGEPAVDHRDVDELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKARLATEALKQVNRVSGSQSPRPARERLLEWPDQELDRVNSFLSSRLQEIKSTVKDSLCASFSTCELDMESSGFQEGTSEPQPQTPTPSDLNGSSEQQPDINLDLSPLTLGSLQSHSLQAPSEPVAAWAERRDPRPPWTETRGPPPGVPENGLVRRLNTVPNLSRVIWVKTPKPGNPNSEQSSKEVPSCKQELSEPVATGGKPRKSKRQGSQVKKTEAGLAPWPPANLEAPSAKSQTSSPKQPGKGPEPAKVGNCAEPGEGSRGSRPGPSWADSPKIEKKGSSWQNWPSEAKARTQEQESVQTPGPAKPQSLSQGKGRSRRSRKQEKSASSLDDVFLPKDMDGVEMDETDREVEYFKRFCLDSAKQTRQKVAVNWTNFSLKKTTPSTAH", "length": 583, "header": "tr|A0A9J7GU77-1|A0A9J7GU77_CRIGR Computationally mapped isoform of Protein FAM193B isoform X2 OS=Cricetulus griseus OX=10029 GN=Fam193b PE=3 SV=1 CANONICAL=A0A8C2LUI4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 477, "start_aa": "Thr", "end_pos": 477, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr477", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LUI4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUI4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770223", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770223", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LUI4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUI4" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LUI4", "url": 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This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035308793", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308793" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LUP2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUP2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pnma2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUP2", "locus": {} } ], "crossref": [ { "id": "100759435", "url": "https://www.ncbi.nlm.nih.gov/gene/100759435", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026523", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026523", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048270", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048270", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759435", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759435", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GPWENEA", "url": "https://omabrowser.org/oma/group/GPWENEA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LUP2", "url": "https://www.orthodb.org/?gene=A0A8C2LUP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23095", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23095", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23095:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23095:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14893", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14893", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20846", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20846", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035308793", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035308793", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LUP2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LUP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUP2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVALLEEWCKIMSVSDQKSLMVTGIPADCGEPEIQAVLQEALKCVGNYRLLGKIFQKQDNTNAVLLELVEDTDMSVVPSEVQGKGGVWKVIFKTPNQDSEFLQRLNLFLEKEGQTIAGMFRALKQEGVSPATPTCTSPELLAHLVGQAMAQAPRPLQPVRYCKLRVFSGNTVPAPEEESFEIWLEQATEIAKEWPIPEAEKKKWMMESLRGPALDLMHIVQGDNPSISVEECLEAFKQVFGSLESRRSSQVRYLKTYQQEGEKISAYVLRLETLLRRAVEKRAIPRNIADQVRLEQVMAGANLTNVLWCRLRELKDQGPLPTFLELMKVIREEEEEEAYFEHESREEPGEREGYGRWDNSRNN", "length": 364, "header": "tr|A0A8C2LUP2-1|A0A8C2LUP2_CRIGR Isoform 1 of Paraneoplastic antigen Ma2 OS=Cricetulus griseus OX=10029 GN=Pnma2 PE=3 SV=1 CANONICAL=A0A8C2LUP2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LUP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUP2/entry#A0A8C2LUP2-1", "sequence": { "sequence": "MAVALLEEWCKIMSVSDQKSLMVTGIPADCGEPEIQAVLQEALKCVGNYRLLGKIFQKQDNTNAVLLELVEDTDMSVVPSEVQGKGGVWKVIFKTPNQDSEFLQRLNLFLEKEGQTIAGMFRALKQEGVSPATPTCTSPELLAHLVGQAMAQAPRPLQPVRYCKLRVFSGNTVPAPEEESFEIWLEQATEIAKEWPIPEAEKKKWMMESLRGPALDLMHIVQGDNPSISVEECLEAFKQVFGSLESRRSSQVRYLKTYQQEGEKISAYVLRLETLLRRAVEKRAIPRNIADQVRLEQVMAGANLTNVLWCRLRELKDQGPLPTFLELMKVIREEEEEEAYFEHESREEPGEREGYGRWDNSRNN", "length": 364, "header": "tr|A0A8C2LUP2-1|A0A8C2LUP2_CRIGR Isoform 1 of Paraneoplastic antigen Ma2 OS=Cricetulus griseus OX=10029 GN=Pnma2 PE=3 SV=1 CANONICAL=A0A8C2LUP2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LUP2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUP2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LUP2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUP2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759435", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759435", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A068-1", "protein_name": "PNMA family member 2", "gene_name": "Pnma2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVALLEEWCKIMGVDVQKSLLVIGIPVNCGELEVQTVLQEALKCVGSYRLLGKILQKQDNTSAVLLELMEDTDMSVVPSEVQGKGGVWKVIFKTPNQDTEFLQRLNLFLEKEGQTVAGMFRALKHEGVSPATTPCTSPELLAHLVGQAMVHAQRPLLPVRYCKLRVFSGSTVAAPEEEPFEVWLEQATEIAKEWPIPETEKKRWVTESLRGPALDLMHIVQADNPSISAEECLEAFKQVFGSMESRRTSQVKYLKTYQQEGEKISAYVLRLETLLRRAVEKRAIPRNIADQVRLEQVMAGANLSNVLWCRLRELKDQGPLPTFLQLMKVVREEEEEEAYFEHESREEPGEREGSGRWDNSRNN", "length": 364 }, "evidence": [ { "id": "A0A8C2LUP2", "url": "https://omabrowser.org/oma/group/A0A8C2LUP2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MJ41-1", "protein_name": "PNMA family member 2", "gene_name": "PNMA2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MALALLEDWCRILSVDDQKSLMVMGIPVDCSEDEIQEVLQETLKPLGRYKLLGKIFRKQENANAVLLELLEDPEVSVIPSKVQGKGGIWKVIFKTPNQDTEFLERLNLFLEKEGQTVSGMFRALGHQGLSPAAMPCISPELLAHVLGQVIAHPPQPLLPMRYRKLRVFSGSAVPAPEEEPFEVWLEQATEIVKEWPVAEAEKKRWLMESLRGPALDLMHIVQADNPSISVEECLEAFKQVFGNLESRRTSQVKYLKTYQEEGEKVSAYVLRLETLLRRAVEKRAIPRNIADQIRLEQVMAGASLSEVLWCRLRELKDQGRPPSFLQLMKVIREEEEEEATFENENTEEPEGGDGYGHWGNEAND", "length": 364 }, "evidence": [ { "id": "A0A8C2LUP2", "url": "https://omabrowser.org/oma/group/A0A8C2LUP2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RJT4-1", "protein_name": "PNMA family member 2", "gene_name": "PNMA2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARALLEDWCRIMSADDQKSLMVMGIPVDCDEAEIQEVLQETLKSLGRYRLLGKIFRKQENANAVLLEFLEDTDVSMIPNEIQGKGGIWKVIFKTPNQDTEFLERLNLFLEKEGQTVSGMFRALGHEGLSPAAVPCVSPELLAHLLGQAIAHAPQPLLPMRYRKLRVFSGSAVPAPEEEPFEIWLEQATEIVKEWPVAEAEKKRWLMESLRGPALDLMHIVQADNPSISVEECLEAFKQVFGSLESRRTSQVKYLKTYQEEGEKVSAYVLRLETLLRRAVEKRAIPRNIADQVRLEQVMAGASLSEILWCRLRELKDQGPPPSFLELMKVIREEEEEEAAFENENIEEPDEGDGYGHWDLEADE", "length": 364 }, "evidence": [ { "id": "A0A8C2LUP2", "url": "https://omabrowser.org/oma/group/A0A8C2LUP2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9UL42-1", "protein_name": "Paraneoplastic antigen Ma2", "gene_name": "PNMA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALALLEDWCRIMSVDEQKSLMVTGIPADFEEAEIQEVLQETLKSLGRYRLLGKIFRKQENANAVLLELLEDTDVSAIPSEVQGKGGVWKVIFKTPNQDTEFLERLNLFLEKEGQTVSGMFRALGQEGVSPATVPCISPELLAHLLGQAMAHAPQPLLPMRYRKLRVFSGSAVPAPEEESFEVWLEQATEIVKEWPVTEAEKKRWLAESLRGPALDLMHIVQADNPSISVEECLEAFKQVFGSLESRRTAQVRYLKTYQEEGEKVSAYVLRLETLLRRAVEKRAIPRRIADQVRLEQVMAGATLNQMLWCRLRELKDQGPPPSFLELMKVIREEEEEEASFENESIEEPEERDGYGRWNHEGDD", "length": 364 }, "evidence": [ { "id": "A0A8C2LUP2", "url": "https://omabrowser.org/oma/group/A0A8C2LUP2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LUP2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUP2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 303, "end_pos": 305, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LUP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUP2" }, { "id": "PF14893", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14893" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Paraneoplastic antigen Ma-like C-terminal", "eco_id": "ECO_0000259", "start_pos": 168, "end_pos": 328, "start_aa": "Phe", "end_aa": "Met", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2LUP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUP2" }, { "id": "PF20846", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20846" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Paraneoplastic antigen Ma-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 92, "start_aa": "Met", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 303, "end_pos": 305 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LUU8-1", "uniprot_ac": "A0A8C2LUU8", "uniprot_id": "A0A8C2LUU8_CRIGR", "mass": { "chemical_mass": 19633.0, "monoisotopic_mass": 19633.0 }, "refseq": { "ac": "XP_027283503", "name": "uncharacterized protein CFAP97D1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283503" }, "gene_names": [ { "name": "Cfap97d1", "type": "recommended", "evidence": [ { "id": "A0A8C2LUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUU8" } ] }, { "name": "Cfap97d1", "type": "synonym", "evidence": [ { "id": "XP_027283503", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283503" } ] } ], "protein_names": [ { "name": "Uncharacterized protein CFAP97D1", "type": "synonym", "evidence": [ { "id": "A0A8C2LUU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUU8/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein CFAP97D1", "type": "synonym", "evidence": [ { "id": "XP_027283503", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283503" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027283503", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283503" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LUU8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUU8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cfap97d1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUU8", "locus": {} } ], "crossref": [ { "id": "100751574", "url": "https://www.ncbi.nlm.nih.gov/gene/100751574", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029488", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029488", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038792", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038792", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751574", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751574", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DHVQWEE", "url": "https://omabrowser.org/oma/group/DHVQWEE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LUU8", "url": "https://www.orthodb.org/?gene=A0A8C2LUU8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33768", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33768", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33768:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33768:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13879", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13879", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027283503", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283503", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LUU8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LUU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUU8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNNSLDYLAYPVIVSNHRQSTTFRKKLDFGHYILHKNRVQIVKPAVDTKPPMAHTHHILKLSKIQGEQKRINKIEYENKQLCQKIANAHRGPAKVDCWNEYLAKSLNREARNRELVRITMENQGILRRLGDRKPHYERRASEMDWQNSRRYIRNTTRYLLNQEE", "length": 164, "header": "tr|A0A8C2LUU8-1|A0A8C2LUU8_CRIGR Isoform 1 of Uncharacterized protein CFAP97D1 OS=Cricetulus griseus OX=10029 GN=Cfap97d1 PE=3 SV=1 CANONICAL=A0A8C2LUU8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LUU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUU8/entry#A0A8C2LUU8-1", "sequence": { "sequence": "MNNSLDYLAYPVIVSNHRQSTTFRKKLDFGHYILHKNRVQIVKPAVDTKPPMAHTHHILKLSKIQGEQKRINKIEYENKQLCQKIANAHRGPAKVDCWNEYLAKSLNREARNRELVRITMENQGILRRLGDRKPHYERRASEMDWQNSRRYIRNTTRYLLNQEE", "length": 164, "header": "tr|A0A8C2LUU8-1|A0A8C2LUU8_CRIGR Isoform 1 of Uncharacterized protein CFAP97D1 OS=Cricetulus griseus OX=10029 GN=Cfap97d1 PE=3 SV=1 CANONICAL=A0A8C2LUU8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LUU8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUU8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3ZAA8-1", "protein_name": "CFAP97 domain containing 1", "gene_name": "Cfap97d1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNNSLDYLAYPVIVSNHRQSTNFRKKLDFGHYILHKNRVQIVKPAVDTSPPMAHTHYILKLSKLQGEQKRIDKIEYENKQLCQKIANAHRGPAKVDCWNEYLSRSLNRESRNRELVKITMENQGILRRLSDRKPHYDRRASEMDWQNSRRYIRNTTRYLLFQEE", "length": 164 }, "evidence": [ { "id": "A0A8C2LUU8", "url": "https://omabrowser.org/oma/group/A0A8C2LUU8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S1I7-1", "protein_name": "CFAP97 domain containing 1", "gene_name": "CFAP97D1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNSSLDYLAYPVIVSNHRQTTSFRKKLDFGHYVFHKNRIQIVKPTVDTKPPVAHTHHILKLSKLQGEQKRIDKIEYENKQLCQKIADAHRGPAQVDCWNEYFSKSLNRETRNRDLVRITVENQGILKRLGDRKPHYDRKSSELDWQNSRRYIRNTTRYLLSQGE", "length": 164 }, "evidence": [ { "id": "A0A8C2LUU8", "url": 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"MNNSLDYLAYPVIVSNHRQSTTFRKKLDFGHYILHKNRVQIVKPAVDTKPPMAHTHYILKLSKIQGEQKRIDKIEYENRQLCQKIANAYRGPAKVDCWNEYLSKSLNRESRNRELVRITMENQGILRRLSDRKPNYDRRSSEMDWQNSRRYIRNTTRYLLFQED", "length": 164 }, "evidence": [ { "id": "A0A8C2LUU8", "url": "https://omabrowser.org/oma/group/A0A8C2LUU8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "sperm axoneme assembly", "id": "GO:0007288", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007288", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LUU8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUU8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2, "end_pos": 4, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2MTM4-1", "uniprot_ac": "A0A8C2MTM4", "uniprot_id": "A0A8C2MTM4_CRIGR", "mass": { "chemical_mass": 33914.0, "monoisotopic_mass": 33914.0 }, "refseq": { "ac": "XP_027283764", "name": "transmembrane and ubiquitin-like domain-containing protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283764" }, "gene_names": [ { "name": "Tmub2", "type": "recommended", "evidence": [ { "id": "A0A8C2MTM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTM4" } ] }, { "name": "Tmub2", "type": "synonym", "evidence": [ { "id": "XP_027283764", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283764" } ] } ], "protein_names": [ { "name": "Transmembrane and ubiquitin-like domain-containing protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8C2MTM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTM4/entry#names_and_taxonomy" } ] }, { "name": "transmembrane and ubiquitin-like domain-containing protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027283764", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283764" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027283764", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283764" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTM4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTM4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tmub2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTM4", "locus": {} } ], "crossref": [ { "id": "cd17132", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17132", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100754122", "url": "https://www.ncbi.nlm.nih.gov/gene/100754122", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754122", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754122", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MGNLMIP", "url": "https://omabrowser.org/oma/group/MGNLMIP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MTM4", "url": "https://www.orthodb.org/?gene=A0A8C2MTM4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3HLJ6", "url": "https://www.orthodb.org/?gene=G3HLJ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14557", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14557", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14557:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14557:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027283764", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283764", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MTM4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MTM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTM4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HLJ6", "url": "https://www.uniprot.org/uniprotkb/G3HLJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3HLJ6-1", "url": "https://www.uniprot.org/uniprotkb/G3HLJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MISRHLQNNLMSVDPVSSQTMELSDVTLIEGVGNEVMVVAGVLVLTLALVLAWLSTYVADSSNNQLLGTIVSAGDPSVLHLGHVDQLVSQGAPEPTELPHPSEGTDEKAEETSDTGGDSTGEPGARGDTEPSLEHLLDIQGLPKRQAGLESPPEAPLGLDDSTCLSPSPSLINVRLKFLNDTEELAVARPEDTVGTLKSKYFPGQESQMKLIYQGRLLQDPARTLSSLNITNNCVIHCHRSPPGAAVSGSSGSLTPSATEPSSLGVNVGSLMVPVFVVLLGVVWYFRINYRQFFTAPATVSLVGVTVFFSFLVFGMYGR", "length": 319, "header": "tr|A0A8C2MTM4-1|A0A8C2MTM4_CRIGR Isoform 1 of Transmembrane and ubiquitin-like domain-containing protein 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tmub2 PE=4 SV=1 CANONICAL=A0A8C2MTM4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MTM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTM4/entry#A0A8C2MTM4-1", "sequence": { "sequence": 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"header": "tr|G3HLJ6-1|A0A8C2MTM4_CRIGR Computationally mapped isoform of Transmembrane and ubiquitin-like domain-containing protein 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tmub2 PE=4 SV=1 CANONICAL=A0A8C2MTM4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HLJ6", "url": "https://www.uniprot.org/uniprotkb/G3HLJ6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3HLJ6", "url": "https://www.uniprot.org/uniprotkb/G3HLJ6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100754122", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754122", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9TZX2-1", "protein_name": "Transmembrane and ubiquitin like domain containing 2", "gene_name": "TMUB2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MISRHLQNNLMSVDPVSSQAMELSDVTLIEGVGNEVTVVAGVVVLILALVLAWLSTYVADSGSNPLLGTIVSAGDTSVLHLGHVDHLVAGQGTPEPTELPHPSEGNDEKAEEAGEGGGDPTGEPGAGGGVEPSLEHLLDIQGLPKRQAGPGNSSLEAPVRSEDSTCLPSSPSLISVRLKFLNDTEELAVARPEDTVGALKSKYFPGQESQMKLIYQGRLLQDPARTLRSLNITDNCVIHCHRSPPGSAVAGPSSSLAPSSTTEPPNLGVSVGSLMVPVFVVLLGVVWYFRINYRQFFTAPATVSLVGVTVFFSFLVFGMYGR", "length": 322 }, "evidence": [ { "id": "A0A8C2MTM4", "url": "https://omabrowser.org/oma/group/A0A8C2MTM4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "I3LNM1-1", "protein_name": "Transmembrane and ubiquitin like domain containing 2", "gene_name": "TMUB2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MELSDVTLIEGVGNEVTVVAGVVVLILALVLAWLSTYVADSGSNQLLGTIVSAGDTSVLHLGHVDHLVAGQGTPEPTELPHPSEGSDEKAEEAGEGGGDSTGEPGAGGGVEPSLEHLLDIQGLPKRHAGPENGRPEAPLRSEESSCLPSGPSLINVRLKFLNDTEELAVARPEDTVGALKSKYFPGQESQMKLIYQGRLLQDPGRTLRSLNITDNCVIHCHRSPPGSAAPGPAAALAPSSATEPPGLGVSVGSLMVPVFVVLLGVVWYFRINYRQFFTAPATVSLVGVTVFFSFLVFGMYGR", "length": 302 }, "evidence": [ { "id": "A0A8C2MTM4", "url": "https://omabrowser.org/oma/group/A0A8C2MTM4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3V209-1", "protein_name": "Transmembrane and ubiquitin-like domain-containing protein 2", "gene_name": "Tmub2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MISRLLQNNLMSVDPVSSQAMELSDVTLIEGVGNEVMVVAGVVALTLALVLAWLSTYVADSGNNQLLGTIVSAGDTSVLHLGHVDQLVNQGTPEPTEHPHPSGGNDDKAEETSDSGGDATGEPGARGEMEPSLEHLLDIQGLPKRQAGLGSSRPEAPLGLDDGSCLSPSPSLINVRLKFLNDTEELAVARPEDTVGTLKSKYFPGQESQMKLIYQGRLLQDPARTLSSLNITNNCVIHCHRSPPGAAVSGPSASLTPTTEQSSLGVNVGSLMVPVFVVLLGVVWYFRINYRQFFTGPATISLVGVTVFFSILVFGMYGR", "length": 319 }, "evidence": [ { "id": "A0A8C2MTM4", "url": "https://omabrowser.org/oma/group/A0A8C2MTM4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q4FZV7-1", "protein_name": "Transmembrane and ubiquitin-like domain-containing protein 2", "gene_name": "Tmub2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MISRHLQNNLMSVDPVSSQAMELSDVTLIEGVGNEVMVVAGVVVLTLALVLAWLSTYVADSSNSQLLGTIVSAGDTSVLHLGHVDQLVNQGTPEPTEHPHPSGGSDDKAEETSDSGGDTTGEPGARGDMEPSLEHLLDIQGLPKRQAGLESSRPEASLGLDDSTCLSPSPSLINVRLKFLNDTEELAVARPEDTVGTLKSKYFPGQESQMKLIYQGRLLQDPARTLSSLNITNNCVIHCHRSPPGAAVSGPSTSLTPTTEQSSLGVNVGSLMVPVFVVLLGVVWYFRINYRQFFTAPATVSLVGVTVFFSFLVFGMYGR", "length": 319 }, "evidence": [ { "id": "A0A8C2MTM4", "url": "https://omabrowser.org/oma/group/A0A8C2MTM4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q71RG4-1", "protein_name": "Transmembrane and ubiquitin-like domain-containing protein 2", "gene_name": "TMUB2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MISRHLQNNLMSVDPASSQAMELSDVTLIEGVGNEVMVVAGVVVLILALVLAWLSTYVADSGSNQLLGAIVSAGDTSVLHLGHVDHLVAGQGNPEPTELPHPSEGNDEKAEEAGEGRGDSTGEAGAGGGVEPSLEHLLDIQGLPKRQAGAGSSSPEAPLRSEDSTCLPPSPGLITVRLKFLNDTEELAVARPEDTVGALKSKYFPGQESQMKLIYQGRLLQDPARTLRSLNITDNCVIHCHRSPPGSAVPGPSASLAPSATEPPSLGVNVGSLMVPVFVVLLGVVWYFRINYRQFFTAPATVSLVGVTVFFSFLVFGMYGR", "length": 321 }, "evidence": [ { "id": "A0A8C2MTM4", "url": "https://omabrowser.org/oma/group/A0A8C2MTM4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTM4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTM4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MTM4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTM4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 180, "end_pos": 182, "annotation": "n_glycosylation_sequon" }, { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MTM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MTM4" }, { "id": "PS50053", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50053" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquitin-like", "eco_id": "ECO_0000259", "start_pos": 172, "end_pos": 245, "start_aa": "Ile", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 180, "end_pos": 182 }, { "start_pos": 229, "end_pos": 231 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2MJD7-1", "uniprot_ac": "A0A8C2MJD7", "uniprot_id": "A0A8C2MJD7_CRIGR", "mass": { "chemical_mass": 60397.0, "monoisotopic_mass": 60397.0 }, "refseq": { "ac": "XP_003510611", "name": "NMDA receptor synaptonuclear signaling and neuronal migration factor isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510611" }, "gene_names": [ { "name": "Nsmf", "type": "recommended", "evidence": [ { "id": "A0A8C2MJD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJD7" } ] }, { "name": "Nsmf", "type": "synonym", "evidence": [ { "id": "XP_003510611", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510611" } ] } ], "protein_names": [ { "name": "NMDA receptor synaptonuclear signaling and neuronal migration factor isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003510611", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510611" }, { "id": "A0A8C2MJD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJD7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614905.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003510611", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510611" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MJD7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJD7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Nsmf", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJD7", "locus": {} } ], "crossref": [ { "id": "100752463", "url": "https://www.ncbi.nlm.nih.gov/gene/100752463", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR033374", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033374", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058542", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058542", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752463", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752463", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GRPCKSW", "url": "https://omabrowser.org/oma/group/GRPCKSW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MJD7", "url": "https://www.orthodb.org/?gene=A0A8C2MJD7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MJK9", "url": "https://www.orthodb.org/?gene=A0A8C2MJK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MMK1", "url": "https://www.orthodb.org/?gene=A0A8C2MMK1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MT41", "url": "https://www.orthodb.org/?gene=A0A8C2MT41", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G7V0", "url": "https://www.orthodb.org/?gene=A0A9J7G7V0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7G852", "url": "https://www.orthodb.org/?gene=A0A9J7G852", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JSR7", "url": "https://www.orthodb.org/?gene=A0A9J7JSR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "G3I5Y3", "url": "https://www.orthodb.org/?gene=G3I5Y3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32061", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32061", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF24609", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24609", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003510611", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003510611", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MJD7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MJD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJD7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MJK9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MJK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJK9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MMK1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MMK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMK1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MT41", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MT41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MT41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MT41-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G7V0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7V0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G7V0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G7V0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G848", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G848", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G848-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G848-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G852", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G852", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7G852-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7G852-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2N0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2N0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H2N0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H2N0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JSR7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JSR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JSR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3I5Y3", "url": "https://www.uniprot.org/uniprotkb/G3I5Y3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3I5Y3-1", "url": "https://www.uniprot.org/uniprotkb/G3I5Y3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGAAASRRRALRSEAMSSVAAKVRAARAFGEYLSQSHPENRNGADHLLADAYSGHDGSPEMQPAPQNKRRLSLVSNGRYEGSISDEAVSGKPATEGPQPRVYTISREPALLPSSEAEAIELAVVKGRRQRERHPHHHSQPLRASPGSSREDVSRPCQSWAGSRQGSKECPGCAQLAPGPSPRAFGLEQPPLPEASGRHKHLERMYSVDRVSDDVPIRTWFPKENLFSFQTATTTMQAISVFRGYAERKRRKRENDSASVIQRNFRKHLRMVGSRRVKAQTFAERRERSFSRSWSDPTPMKADTSHDSRDSSDLQSSHCTLDEACEDLDWDTEKGLEAMACDTEGFLPPKVMLISSKVPKAEYIPTIIRRDDPSIIPILYDHEHATFEDILEEIEKKLNIYHKGAKIWKMLIFCQGGPGHLYLLKNKVATFAKVEKEEDMIHFWKRLSRLMSKVNPEPNVIHIMGCYILGNPNGEKLFQNLRTLMTPYKVTFESPLELSAQGKQMIETYFDFRLYRLWKSRQHSKLLDFDDVL", "length": 532, "header": "tr|A0A8C2MJD7-1|A0A8C2MJD7_CRIGR Isoform 1 of NMDA receptor synaptonuclear signaling and neuronal migration factor isoform X1 OS=Cricetulus griseus OX=10029 GN=Nsmf PE=4 SV=1 CANONICAL=A0A8C2MJD7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MJD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJD7/entry#A0A8C2MJD7-1", "sequence": { "sequence": "MGAAASRRRALRSEAMSSVAAKVRAARAFGEYLSQSHPENRNGADHLLADAYSGHDGSPEMQPAPQNKRRLSLVSNGRYEGSISDEAVSGKPATEGPQPRVYTISREPALLPSSEAEAIELAVVKGRRQRERHPHHHSQPLRASPGSSREDVSRPCQSWAGSRQGSKECPGCAQLAPGPSPRAFGLEQPPLPEASGRHKHLERMYSVDRVSDDVPIRTWFPKENLFSFQTATTTMQAISVFRGYAERKRRKRENDSASVIQRNFRKHLRMVGSRRVKAQTFAERRERSFSRSWSDPTPMKADTSHDSRDSSDLQSSHCTLDEACEDLDWDTEKGLEAMACDTEGFLPPKVMLISSKVPKAEYIPTIIRRDDPSIIPILYDHEHATFEDILEEIEKKLNIYHKGAKIWKMLIFCQGGPGHLYLLKNKVATFAKVEKEEDMIHFWKRLSRLMSKVNPEPNVIHIMGCYILGNPNGEKLFQNLRTLMTPYKVTFESPLELSAQGKQMIETYFDFRLYRLWKSRQHSKLLDFDDVL", "length": 532, "header": "tr|A0A8C2MJD7-1|A0A8C2MJD7_CRIGR Isoform 1 of NMDA receptor synaptonuclear signaling and neuronal migration factor isoform X1 OS=Cricetulus griseus OX=10029 GN=Nsmf PE=4 SV=1 CANONICAL=A0A8C2MJD7-1" }, "locus": {} }, { "isoform_ac": "A0A8C2MJK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJD7/entry#A0A8C2MJK9-1", "sequence": { "sequence": "MGAAASRRRALRSEAMSSVAAKVRAARAFGEYLSQSHPENRNGADHLLADAYSGHDGSPEMQPAPQNKRRLSLVSNGRYEGSISDEAVSGKPATEGPQPRVYTISREPALLPSSEAEAIELAVVKGRRQRERHPHHHSQPLRASPGSSREDVSRPCQSWAGSRQGSKECPGCAQLAPGPSPRAFGLEQPPLPEASGRHKHLERMYSVDRVSDDVPIRTWFPKENLFSFQTATTTMQANFRKHLRMVGSRRVKAQTFAERRERSFSRSWSDPTPMKADTSHDSRDSSDLQSSHCTLDEACEDLDWDTEKGLEAMACDTEGFLPPKVMLISSKVPKAEYIPTIIRRDDPSIIPILYDHEHATFEDILEEIEKKLNIYHKGAKIWKMLIFCQGGPGHLYLLKNKVATFAKVEKEEDMIHFWKRLSRLMSKVNPEPNVIHIMGCYILGNPNGEKLFQNLRTLMTPYKVTFESPLELSAQGKQMIETYFDFRLYRLWKSRQHSKLLDFDDVL", "length": 507, "header": "tr|A0A8C2MJK9-1|A0A8C2MJK9_CRIGR Computationally mapped isoform of NMDA receptor synaptonuclear signaling and neuronal migration factor isoform X4 OS=Cricetulus griseus OX=10029 GN=Nsmf PE=4 SV=1 CANONICAL=A0A8C2MJD7-1" }, "locus": {} }, { "isoform_ac": "A0A8C2MMK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJD7/entry#A0A8C2MMK1-1", "sequence": { "sequence": "MGAAASRRRALRSEAMSSVAAKVRAARAFGEYLSQSHPENRNGADHLLADAYSGHDGSPEMQPAPQNKRRLSLVSNGRYEGSISDEAVSGKPATEGPQPRVYTISREPALLPSSEAEAIELAVVKGRRQRERHPHHHSQPLRASPGSSREDVSRPCQSWAGSRQGSKECPGCAQLAPGPSPRAFGLEQPPLPEASGRHKHLERMYSVDRVSDDVPIRTWFPKENLFSFQTATTTMQAISNFRKHLRMVGSRRVKAQTFAERRERSFSRSWSDPTPMKADTSHDSRDSSDLQSSHCTLDEACEDLDWDTEKGLEAMACDTEGFLPPKVMLISSKVPKAEYIPTIIRRDDPSIIPILYDHEHATFEDILEEIEKKLNIYHKGAKIWKMLIFCQGGPGHLYLLKNKVATFAKVEKEEDMIHFWKRLSRLMSKVNPEPNVIHIMGCYILGNPNGEKLFQNLRTLMTPYKVTFESPLELSAQGKQMIETYFDFRLYRLWKSRQHSKLLDFDDVL", "length": 509, "header": "tr|A0A8C2MMK1-1|A0A8C2MMK1_CRIGR Computationally mapped isoform of NMDA receptor synaptonuclear signaling and neuronal migration factor isoform X3 OS=Cricetulus griseus OX=10029 GN=Nsmf PE=4 SV=1 CANONICAL=A0A8C2MJD7-1" }, "locus": {} }, { "isoform_ac": "A0A8C2MT41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJD7/entry#A0A8C2MT41-1", "sequence": { "sequence": "MGAAASRRRALRSEAMSSVAAKVRAARAFGEYLSQSHPENRNGADHLLADAYSGHDGSPEMQPAPQNKRRLSLVSNGRYEGSISDEAVSGKPATEGPQPRVYTISREPALLPSSEAEAIELAVVKGRRQRERHPHHHSQPLRASPGSSREDVSRPCQSWAGSRQGSKECPGCAQLAPGPSPRAFGLEQPPLPEASGRHKHLERMYSVDRVSDDVPIRTWFPKENLFSFQTATTTMQAVFRGYAERKRRKRENDSASVIQRNFRKHLRMVGSRRVKAQSSDLQSSHCTLDEACEDLDWDTEKGLEAMACDTEGFLPPKVMLISSKVPKAEYIPTIIRRDDPSIIPILYDHEHATFEDILEEIEKKLNIYHKGAKIWKMLIFCQGGPGHLYLLKNKVATFAKVEKEEDMIHFWKRLSRLMSKVNPEPNVIHIMGCYILGNPNGEKLFQNLRTLMTPYKVTFESPLELSAQGKQMIETYFDFRLYRLWKSRQHSKLLDFDDVL", "length": 500, "header": "tr|A0A8C2MT41-1|A0A8C2MT41_CRIGR Computationally mapped isoform of NMDA receptor synaptonuclear signaling and neuronal migration factor isoform X6 OS=Cricetulus griseus OX=10029 GN=Nsmf PE=4 SV=1 CANONICAL=A0A8C2MJD7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G7V0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJD7/entry#A0A9J7G7V0-1", "sequence": { "sequence": "MGAAASRRRALRSEAMSSVAAKVRAARAFGEYLSQSHPENRNGADHLLADAYSGHDGSPEMQPAPQNKRRLSLVSNGRYEGSISDEAVSGKPATEGPQPRVYTISREPALLPSSEAEAIELAVVKGRRQRERHPHHHSQPLRASPGSSREDVSRPCQSWAGSRQGSKECPGCAQLAPGPSPRAFGLEQPPLPEASGRHKHLERMYSVDRVSDDVPIRTWFPKENLFSFQTATTTMQAISVFRGYAERKRRKRENDSASVIQRNFRKHLRMVGSRRVKAQSSDLQSSHCTLDEACEDLDWDTEKGLEAMACDTEGFLPPKVMLISSKVPKAEYIPTIIRRDDPSIIPILYDHEHATFEDILEEIEKKLNIYHKGAKIWKMLIFCQGGPGHLYLLKNKVATFAKVEKEEDMIHFWKRLSRLMSKVNPEPNVIHIMGCYILGNPNGEKLFQNLRTLMTPYKVTFESPLELSAQGKQMIETYFDFRLYRLWKSRQHSKLLDFDDVL", "length": 502, "header": "tr|A0A9J7G7V0-1|A0A9J7G7V0_CRIGR Computationally mapped isoform of NMDA receptor synaptonuclear signaling and neuronal migration factor isoform X5 OS=Cricetulus griseus OX=10029 GN=Nsmf PE=4 SV=1 CANONICAL=A0A8C2MJD7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G848-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJD7/entry#A0A9J7G848-1", "sequence": { "sequence": "MGAAASRRRALRSEAMSSVAAKVRAARAFGEYLSQSHPENRNGADHLLADAYSGHDGSPEMQPAPQNKRRLSLVSNGRYEGSISDEAVSGKPATEGPQPRVYTISREPALLPSSEAEAIELAVVKGRRQRERHPHHHSQPLRASPGSSREDVSRPCQSWAGSRQGSKECPGCAQLAPGPSPRAFGLEQPPLPEASGRHKHLERMYSVDRVSDDVPIRTWFPKENLFSFQTATTTMQAISVFRGYAERKRRKRENDSASVIQRNFRKHLRMVGSRRVKAQTFAERRERSFSRSWSDPTPMKADTSHDSRDSSDLQSSHCTLDEACEDLDWDTEKGLEAMACDTEGFLPPKVMLISSKVPKAEYIPTIIRRDDPSIIPILYDHEHATFEDILEEIEKKLNIYHKGAKIWKMLIFCQGGPGHLYLLKNKVATFAKVEKEEDMIHSVMGPSALS", "length": 450, "header": "tr|A0A9J7G848-1|A0A9J7G848_CRIGR Computationally mapped isoform of NMDA receptor synaptonuclear signaling and neuronal migration factor isoform X10 OS=Cricetulus griseus OX=10029 GN=Nsmf PE=4 SV=1 CANONICAL=A0A8C2MJD7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7G852-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJD7/entry#A0A9J7G852-1", "sequence": { "sequence": "MGAAASRRRALRSEAMSSVAAKVRAARAFGEYLSQSHPENRNGADHLLADAYSGHDGSPEMQPAPQNKRRLSLVSNGRYEGSISDEAVSGKPATEGPQPRVYTISREPALLPSSEAEAIELAVVKGRRQRERHPHHHSQPLRASPGSSREDVSRPCQSWAGSRQGSKECPGCAQLAPGPSPRAFGLEQPPLPEASGRHKHLERMYSVDRVSDDVPIRTWFPKENLFSFQTATTTMQAISNFRKHLRMVGSRRVKAQSSDLQSSHCTLDEACEDLDWDTEKGLEAMACDTEGFLPPKVMLISSKVPKAEYIPTIIRRDDPSIIPILYDHEHATFEDILEEIEKKLNIYHKGAKIWKMLIFCQGGPGHLYLLKNKVATFAKVEKEEDMIHFWKRLSRLMSKVNPEPNVIHIMGCYILGNPNGEKLFQNLRTLMTPYKVTFESPLELSAQGKQMIETYFDFRLYRLWKSRQHSKLLDFDDVL", "length": 479, "header": "tr|A0A9J7G852-1|A0A9J7G852_CRIGR Computationally mapped isoform of NMDA receptor synaptonuclear signaling and neuronal migration factor isoform X7 OS=Cricetulus griseus OX=10029 GN=Nsmf PE=4 SV=1 CANONICAL=A0A8C2MJD7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H2N0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJD7/entry#A0A9J7H2N0-1", "sequence": { "sequence": "MGAAASRRRALRSEAMSSVAAKVRAARAFGEYLSQSHPENRNGADHLLADAYSGHDGSPEMQPAPQNKRRLSLVSNGRYEGSISDEAVSGKPATEGPQPRVYTISREPALLPSSEAEAIELAVVKGRRQRERHPHHHSQPLRASPGSSREDVSRPCQSWAGSRQGSKECPGCAQLAPGPSPRAFGLEQPPLPEASGRHKHLERMYSVDRVSDDVPIRTWFPKENLFSFQTATTTMQAISVFRGYAERKRRKRENDSASVIQRNFRKHLRMVGSRRVKAQTFAERRERSFSRSWSDPTPMKADTSHDSRDSSDLQSSHCTLDEACEDLDWDTEKGLEAMACDTEGFLPPKVMLISSKVPKAEYIPTIIRRDDPSIIPILYDHEHATFEDILEEIEKKLNIYHKGAKIWKMLIFCQLLEEVEPPDEQSEPRAECHPYHGLLHSGEPQWGEAISEPQDPHDSLQGYL", "length": 464, "header": "tr|A0A9J7H2N0-1|A0A9J7H2N0_CRIGR Computationally mapped isoform of NMDA receptor synaptonuclear signaling and neuronal migration factor isoform X9 OS=Cricetulus griseus OX=10029 GN=Nsmf PE=4 SV=1 CANONICAL=A0A8C2MJD7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JSR7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJD7/entry#A0A9J7JSR7-1", "sequence": { "sequence": "MGAAASRRRALRSEAMSSVAAKVRAARAFGEYLSQSHPENRNGADHLLADAYSGHDGSPEMQPAPQNKRRLSLVSNGRYEGSISDEAVSGKPATEGPQPRVYTISREPALLPSSEAEAIELAVVKGRRQRERHPHHHSQPLRASPGSSREDVSRPCQSWAGSRQGSKECPGCAQLAPGPSPRAFGLEQPPLPEASGRHKHLERMYSVDRVSDDVPIRTWFPKENLFSFQTATTTMQANFRKHLRMVGSRRVKAQSSDLQSSHCTLDEACEDLDWDTEKGLEAMACDTEGFLPPKVMLISSKVPKAEYIPTIIRRDDPSIIPILYDHEHATFEDILEEIEKKLNIYHKGAKIWKMLIFCQGGPGHLYLLKNKVATFAKVEKEEDMIHFWKRLSRLMSKVNPEPNVIHIMGCYILGNPNGEKLFQNLRTLMTPYKVTFESPLELSAQGKQMIETYFDFRLYRLWKSRQHSKLLDFDDVL", "length": 477, "header": "tr|A0A9J7JSR7-1|A0A9J7JSR7_CRIGR Computationally mapped isoform of NMDA receptor synaptonuclear signaling and neuronal migration factor isoform X8 OS=Cricetulus griseus OX=10029 GN=Nsmf PE=4 SV=1 CANONICAL=A0A8C2MJD7-1" }, "locus": {} }, { "isoform_ac": "G3I5Y3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJD7/entry#G3I5Y3-1", "sequence": { "sequence": "MGAAASRRRALRSEAMSSVAAKVRAARAFGEYLSQSHPENRNGADHLLADAYSGHDGSPEMQPAPQNKRRLSLVSNGRYEGSISDEAVSGKPATEGPQPRVYTISREPALLPSSEAEAIELAVVKGRRQRERHPHHHSQPLRASPGSSREDVSRPCQSWAGSRQGSKECPGCAQLAPGPSPRAFGLEQPPLPEASGRHKHLERMYSVDRVSDDVPIRTWFPKENLFSFQTATTTMQAVFRGYAERKRRKRENDSASVIQRNFRKHLRMVGSRRVKAQTFAERRERSFSRSWSDPTPMKADTSHDSRDSSDLQSSHCTLDEACEDLDWDTEKGLEAMACDTEGFLPPKVMLISSKVPKAEYIPTIIRRDDPSIIPILYDHEHATFEDILEEIEKKLNIYHKGAKIWKMLIFCQGGPGHLYLLKNKVATFAKVEKEEDMIHFWKRLSRLMSKVNPEPNVIHIMGCYILGNPNGEKLFQNLRTLMTPYKVTFESPLELSAQGKQMIETYFDFRLYRLWKSRQHSKLLDFDDVL", "length": 530, "header": "tr|G3I5Y3-1|A0A8C2MJD7_CRIGR Computationally mapped isoform of NMDA receptor synaptonuclear signaling and neuronal migration factor isoform X1 OS=Cricetulus griseus OX=10029 GN=Nsmf PE=4 SV=1 CANONICAL=A0A8C2MJD7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3I5Y3", "url": "https://www.uniprot.org/uniprotkb/G3I5Y3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3I5Y3", "url": "https://www.uniprot.org/uniprotkb/G3I5Y3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752463", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752463", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AX72-1", "protein_name": "NMDA receptor synaptonuclear signaling and neuronal migration factor", "gene_name": "NSMF", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGAVASRRRALRSEAMSSVAAKVRAARAFGEYLSQSHPENRNGADHLLADAYSGHDGSPEMQPAPQNKRRLSLISNGRYEGSLPEEAVRGKPTGEGPQPRVYTISGEPTLLPGPEAEAIELAVVKGRRQRERHPHHHSQPLRASPGGSHEDVSRPCQSWAGSRQGSKECPGCAQLAPSPSPQAFGLDQPPLPEATSRRKKLERMYSVDRVSDDVPIRTWFPKENLFSFQTATTTMQAISVFRGYAERKRRKRENDSASVIQRNFRKHLRMVGSRRVKAQTFAERRERSFSRSWSDPTPMKADTSHDSRDSGDLQSSHCTLGEAFEDLDWETEKGLEAVACDTEGFVPPKVMLISSKVPKAEYLPTIIRRDDPSIIPILYDHEHATFEDILEEIEKKLNVYHKGAKIWKLLIFCQGGPGHLYLLKNKVATFAKVEKEEDMIHFWKRLSRLMSKVNPEPNVIHVMGCYILGNPNGEKLFQNLRSLMTPYRVTFESPLELSAQGKQMIETYFDFRLYRLWKSRQHSKLLDFEDVL", "length": 532 }, "evidence": [ { "id": "A0A8C2MJD7", "url": "https://omabrowser.org/oma/group/A0A8C2MJD7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q6X4W1-1", "protein_name": "NMDA receptor synaptonuclear signaling and neuronal migration factor", "gene_name": "NSMF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGAAASRRRALRSEAMSSVAAKVRAARAFGEYLSQSHPENRNGADHLLADAYSGHDGSPEMQPAPQNKRRLSLVSNGCYEGSLSEEPSIRKPAGEGPQPRVYTISGEPALLPSPEAEAIELAVVKGRRQRHPHHHSQPLRASPGGSREDVSRPCQSWAGSRQGSKECPGCAQLAPGPTPRAFGLDQPPLPETSGRRKKLERMYSVDRVSDDIPIRTWFPKENLFSFQTATTTMQAISVFRGYAERKRRKRENDSASVIQRNFRKHLRMVGSRRVKAQTFAERRERSFSRSWSDPTPMKADTSHDSRDSSDLQSSHCTLDEAFEDLDWDTEKGLEAVACDTEGFVPPKVMLISSKVPKAEYIPTIIRRDDPSIIPILYDHEHATFEDILEEIERKLNVYHKGAKIWKMLIFCQGGPGHLYLLKNKVATFAKVEKEEDMIHFWKRLSRLMSKVNPEPNVIHIMGCYILGNPNGEKLFQNLRTLMTPYRVTFESPLELSAQGKQMIETYFDFRLYRLWKSRQHSKLLDFDDVL", "length": 530 }, "evidence": [ { "id": "A0A8C2MJD7", "url": "https://omabrowser.org/oma/group/A0A8C2MJD7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99NF2-1", "protein_name": "NMDA receptor synaptonuclear signaling and neuronal migration factor", "gene_name": "Nsmf", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGAAASRRRALRSEAMSSVAAKVRAARAFGEYLSQSHPENRNGADHLLADAYSGHDGSPEMQPAPQNKRRLSLVSNGRYEGSISDEAVSGKPAIEGPQPHVYTISREPALLPGSEAEAIELAVVKGRRQRERHPHHHSQPLRASPGSSREDISRPCQSWAGSRQGSKECPGCAQLVPGPSSRAFGLEQPPLPEAPGRHKKLERMYSVDGVSDDVPIRTWFPKENLFSFQTATTTMQAISVFRGYAERKRRKRENDSASVIQRNFRKHLRMVGSRRVKAQTFAERRERSFSRSWSDPTPMKADTSHDSRDSSDLQSSHCTLDEACEDLDWDTEKGLEAMACNTEGFLPPKVMLISSKVPKAEYIPTIIRRDDPSIIPILYDHEHATFEDILEEIEKKLNIYHKGAKIWKMLIFCQGGPGHLYLLKNKVATFAKVEKEEDMIHFWKRLSRLMSKVNPEPNVIHIMGCYILGNPNGEKLFQNLRTLMTPYKVTFESPLELSAQGKQMIETYFDFRLYRLWKSRQHSKLLDFDDVL", "length": 532 }, "evidence": [ { "id": "A0A8C2MJD7", "url": "https://omabrowser.org/oma/group/A0A8C2MJD7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPI6-1", "protein_name": "NMDA receptor synaptonuclear signaling and neuronal migration factor", "gene_name": "Nsmf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAAASRRRALRSEAMSSVAAKVRAARAFGEYLSQSHPENRNGADHLLADAYSGHEGSPEMQPAPHNKRRLSLVSNGRYEGSISDEAVSGKTATEGPQPRVYTISREPALLPGSEAEAIELAVVKGRRQRERHPHHHSQPLRASPGSSREDISRPCQSWAGSRQGSKECPGCAKLVPGPSPRAFGLEQPPLPEASGRHKKLERMYSVDGVSDDVPIRTWFPKENPFSFQTATTTMQAISVFRGYAERKRRKRENDSASVIQRNFRKHLRMVGSRRVKAQTFAERRERSFSRSWSDPTPMKADTSHDSRDSSDLQSSHCTLDEACEDLDWDTEKGLEATACDTEGFLPPKVMLISSKVPKAEYIPTIIRRDDPSIIPILYDHEHATFEDILEEIEKKLNIYHKGAKIWKMLIFCQGGPGHLYLLKNKVATFAKVEKEEDMIHFWKRLSRLMSKVNPEPNVIHIMGCYILGNPNGEKLFQNLRTLMTPYKVTFESPLELSAQGKQMIETYFDFRLYRLWKSRQHSKLLDFDDVL", "length": 532 }, "evidence": [ { "id": "A0A8C2MJD7", "url": "https://omabrowser.org/oma/group/A0A8C2MJD7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MJD7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJD7" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MJD7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJD7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MJD7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJD7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of neuronal synaptic plasticity", "id": "GO:0048168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048168", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MJD7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MJD7" } ], "pmid": "" }, { "name": "regulation of neuron migration", "id": "GO:2001222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001222", "evidence": [ { 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This record is derived from a genomic sequence (NW_003616017.1) and transcript sequence (JI888700.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003513630", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003513630" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MMZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Fam168a", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ9", "locus": {} } ], "crossref": [ { "id": "100752186", "url": "https://www.ncbi.nlm.nih.gov/gene/100752186", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752186", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752186", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WTNNINI", "url": "https://omabrowser.org/oma/group/WTNNINI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MMZ9", "url": "https://www.orthodb.org/?gene=A0A8C2MMZ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31844", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31844", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14944", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14944", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003513630", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003513630", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2MMZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MMZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GTT8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GTT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GTT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GTT8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K5C8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5C8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7K5C8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5C8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3IFR4", "url": "https://www.uniprot.org/uniprotkb/G3IFR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "G3IFR4-1", "url": "https://www.uniprot.org/uniprotkb/G3IFR4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNPVYSPVQPGAPYGNPKNMAYTGYPTAYPAAAPAYNPSLYPTNSPSYAPEFQFLHSAYATLLMKQAWPQNSSSCGTEGTFHLPVDTGTENRTYQASSAAFRYTAGTPYKVPPTQSNTAPPPYSPSPNPYQTAMYPIRSAYPQQNLYAQGAYYTQPVYAAQPHVIHHTTVVQPNSIPSAIYPAPVAAPRTNGVAMGMVAGTTMAMSAGTLLTTPQHTAIGAHPVSMPTYRAQGTPAYSYVPPHW", "length": 244, "header": "tr|A0A8C2MMZ9-1|A0A8C2MMZ9_CRIGR Isoform 1 of Protein FAM168A isoform X1 OS=Cricetulus griseus OX=10029 GN=Fam168a PE=3 SV=1 CANONICAL=A0A8C2MMZ9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2MMZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ9/entry#A0A8C2MMZ9-1", "sequence": { "sequence": "MNPVYSPVQPGAPYGNPKNMAYTGYPTAYPAAAPAYNPSLYPTNSPSYAPEFQFLHSAYATLLMKQAWPQNSSSCGTEGTFHLPVDTGTENRTYQASSAAFRYTAGTPYKVPPTQSNTAPPPYSPSPNPYQTAMYPIRSAYPQQNLYAQGAYYTQPVYAAQPHVIHHTTVVQPNSIPSAIYPAPVAAPRTNGVAMGMVAGTTMAMSAGTLLTTPQHTAIGAHPVSMPTYRAQGTPAYSYVPPHW", "length": 244, "header": "tr|A0A8C2MMZ9-1|A0A8C2MMZ9_CRIGR Isoform 1 of Protein FAM168A isoform X1 OS=Cricetulus griseus OX=10029 GN=Fam168a PE=3 SV=1 CANONICAL=A0A8C2MMZ9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GTT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ9/entry#A0A9J7GTT8-1", "sequence": { "sequence": "MNPVYSPVQPGAPYGNPKNMAYTGYPTAYPAAAPAYNPSLYPTNSPSYAPATLLMKQAWPQNSSSCGTEGTFHLPVDTGTENRTYQASSAAFRSLLHTACVCCPAPCHPPHHSCPAQQHSLCHLPSPCCCSQDQRCGHGHGSRHHHGNVSRYPADHTPAHCNWGAPRLHAHVQGPRNPRVQLCAPALVKPAAHPNLESHCMQLLTSYTGAGAVP", "length": 214, "header": "tr|A0A9J7GTT8-1|A0A9J7GTT8_CRIGR Computationally mapped isoform of Protein FAM168A isoform X4 OS=Cricetulus griseus OX=10029 GN=Fam168a PE=3 SV=1 CANONICAL=A0A8C2MMZ9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K5C8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ9/entry#A0A9J7K5C8-1", "sequence": { "sequence": "MNPVYSPVQPGAPYGNPKNMAYTGYPTAYPAAAPAYNPSLYPTNSPSYAPEFQFLHSAYATLLMKQAWPQNSSSCGTEGTFHLPVDTGTENRTYQASSAAFRSLLHTACVCCPAPCHPPHHSCPAQQHSLCHLPSPCCCSQDQRCGHGHGSRHHHGNVSRYPADHTPAHCNWGAPRLHAHVQGPRNPRVQLCAPALVKPAAHPNLESHCMQLLTSYTGAGAVP", "length": 223, "header": "tr|A0A9J7K5C8-1|A0A9J7K5C8_CRIGR Computationally mapped isoform of Protein FAM168A isoform X3 OS=Cricetulus griseus OX=10029 GN=Fam168a PE=3 SV=1 CANONICAL=A0A8C2MMZ9-1" }, "locus": {} }, { "isoform_ac": "G3IFR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MMZ9/entry#G3IFR4-1", "sequence": { "sequence": "MNPVYSPVQPGAPYGNPKNMAYTGYPTAYPAAAPAYNPSLYPTNSPSYAPATLLMKQAWPQNSSSCGTEGTFHLPVDTGTENRTYQASSAAFRYTAGTPYKVPPTQSNTAPPPYSPSPNPYQTAMYPIRSAYPQQNLYAQGAYYTQPVYAAQPHVIHHTTVVQPNSIPSAIYPAPVAAPRTNGVAMGMVAGTTMAMSAGTLLTTPQHTAIGAHPVSMPTYRAQGTPAYSYVPPHW", "length": 235, "header": "tr|G3IFR4-1|A0A8C2MMZ9_CRIGR Computationally mapped isoform of Protein FAM168A isoform X1 OS=Cricetulus griseus OX=10029 GN=Fam168a PE=3 SV=1 CANONICAL=A0A8C2MMZ9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3IFR4", "url": "https://www.uniprot.org/uniprotkb/G3IFR4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "G3IFR4", "url": "https://www.uniprot.org/uniprotkb/G3IFR4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752186", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752186", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A572-1", "protein_name": "Family with sequence similarity 168, member A", "gene_name": "Fam168a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNPVYSPVQPGAPYGNPKNMAYTGYPTAYPAAAPAYNPSLYPTSSPSYAPEFQFLHSAYGISPLFPLSFPSGYHDATLLMKQAWPQNSSSCGTEGTFHLPVDTGTENRTYQASSAAFRYTAGTPYKVPPTQSNTAPPPYSPSPNPYQTAMYPIRSAYPQQNLYAQGAYYTQPVYAAQPHVIHHTTVVQPNSIPSAIYPAPVAAPRTNGVAMGMVAGTTMAMSAGTLLTTPQHTAIGAHPVSMPTYRAQGTPAYSYVPPHW", "length": 260 }, "evidence": [ { "id": "A0A8C2MMZ9", "url": "https://omabrowser.org/oma/group/A0A8C2MMZ9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8W4F9R3-1", "protein_name": "Family with sequence similarity 168 member A", "gene_name": "FAM168A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNPVYSPVQPGAPYGNPKNMAYTGYPTAYPAAAPAYNPSLYPTSSPSYAPEFQFLHSAYATLLMKQAWPQNSSSCGTEGTFHLPVDTGTENRTYQASSAAFRYTAGTPYKVPPTQSNTAPPPYSPSPNPYQTAMYPIRSAYPQQNLYAQGAYYTQPVYAAQPHVIHHTTVVQPNSIPSAIYPAPVAAPRTNGVAMGMVAGTTMAMSAGTLLTAPQHTAIGAHPVSMPTYRAQGTPAYSYVPPHW", "length": 244 }, "evidence": [ { "id": "A0A8C2MMZ9", "url": "https://omabrowser.org/oma/group/A0A8C2MMZ9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1N396-1", "protein_name": "Family with sequence similarity 168 member A", "gene_name": "FAM168A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2N1D0-1", "uniprot_ac": "A0A8C2N1D0", "uniprot_id": "A0A8C2N1D0_CRIGR", "mass": { "chemical_mass": 59533.0, "monoisotopic_mass": 59533.0 }, "refseq": { "ac": "XP_003501099", "name": "plexin domain-containing protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501099" }, "gene_names": [ { 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Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613829.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003501099", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501099" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N1D0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1D0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Plxdc2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1D0", "locus": {} } ], "crossref": [ { "id": "100751934", "url": "https://www.ncbi.nlm.nih.gov/gene/100751934", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002165", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002165", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751934", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751934", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2N1D0", "url": "https://www.orthodb.org/?gene=A0A8C2N1D0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13055", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13055", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13055:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13055:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01437", "url": 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"https://www.uniprot.org/uniprotkb/A0A9J7K5S3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARFSRADLAAAGVMLLCHFLTDRFQLAHGEPGHQITDWKYDISKTFPRGEDGVDVDSQAYSHRWKRNLDPFKAVDTNRASMGQDSPESRGFTDLLLDDGQDNTTQIEEDTDHNYYISRIYGPTDSASRDLWVNIDQMEKDKVKIHGILSNTHRQAARVNLSFDFPFYGHFLREITVATGGFIYTGEVVHRMLTATQYIAPLMANFDPSVSRNSTVRYFDNGTALVVQWDHVHLQDNYNLGSFTFQATLLMDGRIIFGYKEIPVLVTQISSTNHPVKVGLSDAFVVVHRIQQIPNVRRRTIYEYHRVELQMSKITNISAVEMTPLPTCLQFNSCGTCVSSQIGFNCSWCSKLQRCSSGFDRHRQDWVDSGCPEEVQSKEKICEGTEPAETSQTTTTSHTTTMQFRVLTTTRRAVTSQLPTSLPTEDDTKIALHLKDNGASTDDSAAEKKGGTLHAGLIVGILILVLIIAAAILVTVYMYHHPTSAASIFFIERRPSRWPAMKFRRGSGHPAYAEVEPVGEKEGFIVSEQC", "length": 530, "header": "tr|A0A8C2N1D0-1|A0A8C2N1D0_CRIGR Isoform 1 of Plexin domain-containing protein 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Plxdc2 PE=3 SV=1 CANONICAL=A0A8C2N1D0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2N1D0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1D0/entry#A0A8C2N1D0-1", "sequence": { 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"MARFSRADLAAAGVMLLCHFLTDRFQLAHGEPGHQITDWKYDISKTFPRGEDGVDVDSQAYSHRWKRNLDPFKAVDTNRASMGQDSPESRGFTDLLLDDGQDNTTQIERVNLSFDFPFYGHFLREITVATGGFIYTGEVVHRMLTATQYIAPLMANFDPSVSRNSTVRYFDNGTALVVQWDHVHLQDNYNLGSFTFQATLLMDGRIIFGYKEIPVLVTQISSTNHPVKVGLSDAFVVVHRIQQIPNVRRRTIYEYHRVELQMSKITNISAVEMTPLPTCLQFNSCGTCVSSQIGFNCSWCSKLQRCSSGFDRHRQDWVDSGCPEESKEKICEGTEPAETSQTTTTSHTTTMQFRVLTTTRRAVTSQLPTSLPTEDDTKIALHLKDNGASTDDSAAEKKGGTLHAGLIVGILILVLIIAAAILVTVYMYHHPTSAASIFFIERRPSRWPAMKFRRGSGHPAYAEVEPVGEKEGFIVSEQC", "length": 479, "header": "tr|A0A8C2N4G9-1|A0A8C2N4G9_CRIGR Computationally mapped isoform of Plexin domain-containing protein 2 isoform X3 OS=Cricetulus griseus OX=10029 GN=Plxdc2 PE=3 SV=1 CANONICAL=A0A8C2N1D0-1" }, "locus": {} }, { "isoform_ac": "A0A9J7K5S3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1D0/entry#A0A9J7K5S3-1", "sequence": { "sequence": "MARFSRADLAAAGVMLLCHFLTDRFQLAHGEPGHQITDWKYDISKTFPRGEDGVDVDSQAYSHRWKRNLDPFKAVDTNRASMGQDSPESRGFTDLLLDDGQDNTTQIEEDTDHNYYISRIYGPTDSASRDLWVNIDQMEKDKVKIHGILSNTHRQAARVNLSFDFPFYGHFLREITVATGGFIYTGEVVHRMLTATQYIAPLMANFDPSVSRNSTVRYFDNGTALVVQWDHVHLQDNYNLGSFTFQATLLMDGRIIFGYKEIPVLVTQISSTNHPVKVGLSDAFVVVHRIQQIPNVRRRTIYEYHRVELQMSKITNISAVEMTPLPTCLQFNSCGTCVSSQIGFNCSWCSKLQRCSSGFDRHRQDWVDSGCPEESKEKICEGTEPAETSQTTTTSHTTTMQFRVLTTTRRAVTSQLPTSLPTEDDTKIALHLKDNGASTDDSAAEKKGGTLHAGLIVGILILVLIIAAAILVTVYMYHHPTSAASIFFIERRPSRWPAMKFRRGSGHPAYAEVEPVGEKEGFIVSEQC", "length": 528, "header": "tr|A0A9J7K5S3-1|A0A8C2N1D0_CRIGR Computationally mapped isoform of Plexin domain-containing protein 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Plxdc2 PE=3 SV=1 CANONICAL=A0A8C2N1D0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K5S3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5S3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A9J7K5S3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7K5S3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751934", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751934", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N1D0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2N1D0" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2N1D0", "url": 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This record is derived from a genomic sequence (NW_003614673.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003509295", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509295" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LV73", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LV73" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100770085", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LV73", "locus": {} } ], "crossref": [ { "id": "cd03593", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03593", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100770085", "url": "https://www.ncbi.nlm.nih.gov/gene/100770085", "database": "GeneID", "categories": [ 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"database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LV73", "url": "https://www.orthodb.org/?gene=A0A8C2LV73", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46490", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46490", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46490:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46490:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003509295", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509295", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061HVV5", "url": "https://www.uniprot.org/uniprotkb/A0A061HVV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061HVV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A061HVV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LV73", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LV73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LV73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LV73-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LVE6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LVE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVE6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQDEDGYITLNIKPRKPTLSSADSASSWWRVMALILLISSMGLVVGLVALGIMSVTQQRYPLAEKESLSATLQQLAKKFCQELIKQSELKTKNTAEHKCSPCASRWRYHGDSCYGFFRHNRTWEESKQYCAEQNATLVKAASQGTVEYLTSRITSVRWIGLSRQNSNKDWMWEDSSVLPKNMIDLSGNPRENMNCAYLYNGKIHPASCEDRHYLMCERKAGLPRVDQLL", "length": 229, "header": "tr|A0A8C2LV73-1|A0A8C2LV73_CRIGR Isoform 1 of C-type lectin domain family 1 member B isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100770085 PE=4 SV=1 CANONICAL=A0A8C2LV73-1" }, "isoforms": [ { "isoform_ac": "A0A061HVV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LV73/entry#A0A061HVV5-1", "sequence": { "sequence": "MQDEDGYITLNIKPRKPTLSSAVTQQRYPLAEKESLSATLQQLAKKFCQELIKQSELKTKNTAEHKCSPCASRWRYHGDSCYGFFRHNRTWEESKQYCAEQNATLVKAASQGTVEYLTSRITSVRWIGLSRQNSNKDWMWEDSSVLPKNMIDLSGNPRENMNCAYLYNGKIHPASCEDRHYLMCERKAGLPRVDQLL", "length": 197, "header": "tr|A0A061HVV5-1|A0A8C2LV73_CRIGR Computationally mapped isoform of C-type lectin domain family 1 member B isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100770085 PE=4 SV=1 CANONICAL=A0A8C2LV73-1" }, "locus": {} }, { "isoform_ac": "A0A8C2LV73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LV73/entry#A0A8C2LV73-1", "sequence": { "sequence": "MQDEDGYITLNIKPRKPTLSSADSASSWWRVMALILLISSMGLVVGLVALGIMSVTQQRYPLAEKESLSATLQQLAKKFCQELIKQSELKTKNTAEHKCSPCASRWRYHGDSCYGFFRHNRTWEESKQYCAEQNATLVKAASQGTVEYLTSRITSVRWIGLSRQNSNKDWMWEDSSVLPKNMIDLSGNPRENMNCAYLYNGKIHPASCEDRHYLMCERKAGLPRVDQLL", "length": 229, "header": "tr|A0A8C2LV73-1|A0A8C2LV73_CRIGR Isoform 1 of C-type lectin domain family 1 member B isoform X1 OS=Cricetulus griseus OX=10029 GN=LOC100770085 PE=4 SV=1 CANONICAL=A0A8C2LV73-1" }, "locus": {} }, { "isoform_ac": "A0A8C2LVE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LV73/entry#A0A8C2LVE6-1", "sequence": { "sequence": "MQDEDGYITLNIKPRKPTLSSAVTQQRYPLAEKESLSATLQQLAKKFCQELIKQSELKTKNTAGIPHKQDYFCPLDWIITSEL", "length": 83, "header": "tr|A0A8C2LVE6-1|A0A8C2LVE6_CRIGR Computationally mapped isoform of C-type lectin domain family 1 member B isoform X3 OS=Cricetulus griseus OX=10029 GN=LOC100770085 PE=4 SV=1 CANONICAL=A0A8C2LV73-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061HVV5", "url": "https://www.uniprot.org/uniprotkb/A0A061HVV5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A061HVV5", "url": "https://www.uniprot.org/uniprotkb/A0A061HVV5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100770085", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100770085", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GBW7-1", "protein_name": "C-type lectin domain family 1, member B", "gene_name": "Clec1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQDEDGYITLNIKPRKQALSSAVTQQKYLLAEKENLSATLQQLAKKFCQELIRQSEIKTKSSFEHKCSPCATKWRYHGDSCYGFFRRNLTWEDSKLFCSEQNATLVKTASQSTLKYITDRITSVRWIGLSRQNSKKDWMWEDSSVLHNNSIDLSRNTEENMNCAYLHNGKIHPASCTERHYLICERNAALTRVEQLL", "length": 197 }, "evidence": [ { "id": "A0A8C2LV73", "url": "https://omabrowser.org/oma/group/A0A8C2LV73/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LNV9-1", "protein_name": "C-type lectin domain family 1 member B", "gene_name": "CLEC1B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQDEDGYVTLNVKTEKPALTSGAPAASSLWRVMALILLVLCIGMVFGLVALGILSITQQHNLRAENEHLSGTLKQLARKVCQDLIKQSGQEERHQCSPCEKNWRYHGDSCYGFFRHNLTWEESKKYCIDTSATLLKIPSQNILQYLTSRTGLIRWVGLSRQNSKEAWMWEDGSVPSKNVIKFSGNGTENMNCAYFHNGKIHPTFCENKHYLMCERKAGMPKVDQLL", "length": 226 }, "evidence": [ { "id": "A0A8C2LV73", "url": "https://omabrowser.org/oma/group/A0A8C2LV73/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9JL99-1", "protein_name": "C-type lectin domain family 1 member B", "gene_name": "Clec1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQDEDGYITLNIKPRKQALSSAEPASSWWRVMALVLLISSMGLVVGLVALGIMSVTQQKYLLAEKENLSATLQQLAKKFCQELIRQSEIKTKSTFEHKCSPCATKWRYHGDSCYGFFRRNLTWEESKQYCTEQNATLVKTASQSTLDYIAERITSVRWIGLSRQNSKKDWMWEDSSVLRKNGINLSGNTEENMNCAYLHNGKIHPASCKERHYLICERNAGMTRVDQLL", "length": 229 }, "evidence": [ { "id": "A0A8C2LV73", "url": "https://omabrowser.org/oma/group/A0A8C2LV73/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9P126-1", "protein_name": "C-type lectin domain family 1 member B", "gene_name": "CLEC1B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQDEDGYITLNIKTRKPALISVGSASSSWWRVMALILLILCVGMVVGLVALGIWSVMQRNYLQGENENRTGTLQQLAKRFCQYVVKQSELKGTFKGHKCSPCDTNWRYYGDSCYGFFRHNLTWEESKQYCTDMNATLLKIDNRNIVEYIKARTHLIRWVGLSRQKSNEVWKWEDGSVISENMFEFLEDGKGNMNCAYFHNGKMHPTFCENKHYLMCERKAGMTKVDQLP", "length": 229 }, "evidence": [ { "id": "A0A8C2LV73", "url": "https://omabrowser.org/oma/group/A0A8C2LV73/", "database": "OMA" } ], "glygen_name": "Human", 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This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035301854", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301854" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MSR0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSR0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tex35", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSR0", "locus": {} } ], "crossref": [ { "id": "100774314", "url": "https://www.ncbi.nlm.nih.gov/gene/100774314", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027874", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027874", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774314", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774314", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A061I278", "url": "https://www.orthodb.org/?gene=A0A061I278", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MSR0", "url": "https://www.orthodb.org/?gene=A0A8C2MSR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR36860", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36860", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR36860:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36860:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15079", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15079", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035301854", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035301854", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A061I278", "url": "https://www.uniprot.org/uniprotkb/A0A061I278", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A061I278-1", "url": "https://www.uniprot.org/uniprotkb/A0A061I278-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MSR0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MSR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSR0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVKRADLRKTNLKKNYKAVSLELKPELTQIYDYKGFKPEGLPIKKGMTQELKNELRQVREELKEKMEEIKQIKDIMDKDFDKLHEFVEIMKEMQKDMDEKMDVLINIQKNNKLPPPKQPKEQQELGQIGKMDKDPQFRFKKMEEPDGAPLTGDKMMMSQKTKNNLLDSSHACQSCCETFTPRLGALFTFVIWSCFLIYLYFNPDEMEYVLPT", "length": 213, "header": "tr|A0A8C2MSR0-1|A0A8C2MSR0_CRIGR Isoform 1 of Testis-expressed protein 35 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tex35 PE=4 SV=1 CANONICAL=A0A8C2MSR0-1" }, "isoforms": [ { "isoform_ac": "A0A061I278-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSR0/entry#A0A061I278-1", "sequence": { "sequence": "MSVKRADLRKTNLKKNYKAVSLELKPELTQIYDYKGFKPEGLPIKKGMTQELKNELRQVREELKEKMEEIKQIKDIMDKDFDKLHEFVEIMKEMQKDMDEKMDVLINIQKNNKLPPPKQPKEQQELGQIGKMDKDPQFRFKKMEEPDGAPLTGDKMMMSQKTKNNLLDSSHACQSCCEKCLLCALKTNCHKGKPSHHAWARFSPLSSGAAF", "length": 211, "header": "tr|A0A061I278-1|A0A8C2MSR0_CRIGR Computationally mapped isoform of Testis-expressed protein 35 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tex35 PE=4 SV=1 CANONICAL=A0A8C2MSR0-1" }, "locus": {} }, { "isoform_ac": "A0A8C2MSR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MSR0/entry#A0A8C2MSR0-1", "sequence": { "sequence": "MSVKRADLRKTNLKKNYKAVSLELKPELTQIYDYKGFKPEGLPIKKGMTQELKNELRQVREELKEKMEEIKQIKDIMDKDFDKLHEFVEIMKEMQKDMDEKMDVLINIQKNNKLPPPKQPKEQQELGQIGKMDKDPQFRFKKMEEPDGAPLTGDKMMMSQKTKNNLLDSSHACQSCCETFTPRLGALFTFVIWSCFLIYLYFNPDEMEYVLPT", "length": 213, "header": "tr|A0A8C2MSR0-1|A0A8C2MSR0_CRIGR Isoform 1 of Testis-expressed protein 35 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tex35 PE=4 SV=1 CANONICAL=A0A8C2MSR0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 18 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613590.1) and transcript sequence (JI889538.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007638336", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638336" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MDN3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MDN3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Srpx", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MDN3", "locus": {} } ], "crossref": [ { "id": "cd00033", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00033", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100765667", "url": "https://www.ncbi.nlm.nih.gov/gene/100765667", "database": "GeneID", "categories": [ "Genome 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"database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46343", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46343", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46343:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46343:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00084", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00084", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02494", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02494", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13778", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13778", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007638336", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007638336", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7H280", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H280", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7H280-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H280-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MDN3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MDN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MDN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MDN3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSPGLGSVLFLPQALLLLLLVLLLRVPPSRGFPGSGDSPLEDDGVWYSHSLYKDTPWCSPIKVKYGDVYCRAPPGGYYKTALGTRCDIRCRKGYELHGSSQLICQSNKRWSDKVICKQKRCPTLAMPANGGFKCVDGAYFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPATCVDMEPPRIKCPSVKERIAEPNKLTVRVSWETPEGRDTADGILTDVILKGLPPGSNFPEGDHKIEYTVYDRAENKGTCKFRVKVRVRRCGKLNVPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTCAAMNVNVGVRTAAALLDQFYEKRRLLIVSTPTARNLLYRMQLGMLQQAQCGLDLRHVTVVELVGVFPTLIGRIRAKIMPPALALQLRLLLRIPLYSFSMVLVDKHGMDKERYVSLVTPMALFNLIDTFPLRKEEMILQAEMGQTCNT", "length": 466, "header": "tr|A0A8C2MDN3-1|A0A8C2MDN3_CRIGR Isoform 1 of Sushi repeat-containing protein SRPX isoform X2 OS=Cricetulus griseus OX=10029 GN=Srpx PE=4 SV=1 CANONICAL=A0A8C2MDN3-1" }, "isoforms": [ { "isoform_ac": "A0A3L7H280-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MDN3/entry#A0A3L7H280-1", "sequence": { "sequence": "MGSPGLGSVLFLPQALLLLLLVLLLRVPPSRGFPDTPWCSPIKVKYGDVYCRAPPGGYYKTALGTRCDIRCRKGYELHGSSQLICQSNKRWSDKVICKQKRCPTLAMPANGGFKCVDGAYFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPATCVDMEPPRIKCPSVKERIAEPNKLTVRVSWETPEGRDTADGILTDVILKGLPPGSNFPEGDHKIEYTVYDRAENKGTCKFRVKVRVRRCGKLNVPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTCAAMNVNVGVRTAAALLDQFYEKRRLLIVSTPTARNLLYRMQLGMLQQAQCGLDLRHVTVVELVGVFPTLIGRIRAKIMPPALALQLRLLLRIPLYSFSMVLVDKHGMDKERYVSLVTPMALFNLIDTFPLRKEEMILQAEMGQTCNT", "length": 446, "header": "tr|A0A3L7H280-1|A0A8C2MDN3_CRIGR Computationally mapped isoform of Sushi repeat-containing protein SRPX isoform X2 OS=Cricetulus griseus OX=10029 GN=Srpx PE=4 SV=1 CANONICAL=A0A8C2MDN3-1" }, "locus": {} }, { "isoform_ac": "A0A8C2MDN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MDN3/entry#A0A8C2MDN3-1", "sequence": { "sequence": "MGSPGLGSVLFLPQALLLLLLVLLLRVPPSRGFPGSGDSPLEDDGVWYSHSLYKDTPWCSPIKVKYGDVYCRAPPGGYYKTALGTRCDIRCRKGYELHGSSQLICQSNKRWSDKVICKQKRCPTLAMPANGGFKCVDGAYFNSRCEYYCSPGYTLKGERTVTCMDNKAWSGRPATCVDMEPPRIKCPSVKERIAEPNKLTVRVSWETPEGRDTADGILTDVILKGLPPGSNFPEGDHKIEYTVYDRAENKGTCKFRVKVRVRRCGKLNVPENGYMKCSSDGDNYGATCEFSCIGGYELQGSPARVCQSNLAWSGTEPTCAAMNVNVGVRTAAALLDQFYEKRRLLIVSTPTARNLLYRMQLGMLQQAQCGLDLRHVTVVELVGVFPTLIGRIRAKIMPPALALQLRLLLRIPLYSFSMVLVDKHGMDKERYVSLVTPMALFNLIDTFPLRKEEMILQAEMGQTCNT", "length": 466, "header": "tr|A0A8C2MDN3-1|A0A8C2MDN3_CRIGR Isoform 1 of Sushi repeat-containing protein SRPX isoform X2 OS=Cricetulus griseus OX=10029 GN=Srpx PE=4 SV=1 CANONICAL=A0A8C2MDN3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H280", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H280" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7H280", "url": "https://www.uniprot.org/uniprotkb/A0A3L7H280" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765667", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765667", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "phagolysosome assembly", "id": "GO:0001845", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001845", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MDN3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MDN3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2MDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MDN3" }, { "id": "PS50825", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50825" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HYR", "eco_id": "ECO_0000259", "start_pos": 177, "end_pos": 261, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2MDN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MDN3" }, { "id": "PS50923", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50923" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sushi", "eco_id": "ECO_0000259", "start_pos": 69, "end_pos": 119, "start_aa": "Val", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2MKV3-1", "uniprot_ac": "A0A8C2MKV3", "uniprot_id": "A0A8C2MKV3_CRIGR", "mass": { "chemical_mass": 43060.0, "monoisotopic_mass": 43060.0 }, "refseq": { "ac": "XP_003502597", "name": "testicular haploid expressed gene protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502597" }, "gene_names": [ { "name": "Theg", "type": "recommended", "evidence": [ { "id": "A0A8C2MKV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MKV3" } ] }, { "name": "Theg", "type": "synonym", "evidence": [ { "id": "XP_003502597", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502597" } ] } ], "protein_names": [ { "name": "Testicular haploid expressed gene protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8C2MKV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MKV3/entry#names_and_taxonomy" } ] }, { "name": "testicular haploid expressed gene protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003502597", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502597" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613904.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003502597", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502597" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MKV3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MKV3" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Theg", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MKV3", "locus": {} } ], "crossref": [ { "id": "100760485", "url": "https://www.ncbi.nlm.nih.gov/gene/100760485", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100760485", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760485", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YAWISPR", "url": "https://omabrowser.org/oma/group/YAWISPR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A3L7HHU3", "url": "https://www.orthodb.org/?gene=A0A3L7HHU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2MKV3", "url": "https://www.orthodb.org/?gene=A0A8C2MKV3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15901", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15901", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15901:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15901:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003502597", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502597", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A3L7HHU3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HHU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3L7HHU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HHU3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MKV3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MKV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2MKV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MKV3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGELGEHRASLLNNFVLEAKASGASGHGQSDTLGSGNMGLQSTTFESPWLQSSQATHAGLASEDTEEDVPPEEVPGEELLEIPNLDDRLRRELEVEVVEMSQLSISEPTPSISIARGRRKKSRRLMELAKPKTNWQCLRDRTGCCCKGYAWISPHKSNLQFCLYWPSVYWTERFMEDTTLTITVPAVSRRVEELSRPKRFYLEYYNNNRTTPIWPIPRSTLEYQPSNRLKQLATPKVRNNIWSIDMSEISQVSRAAQTAVPTPRTLNLAKPRPPAILMEEWDPMPKPKPHVSDHNRLLQLATPKALSEKCVPDRNPQWEILDVTKKAVASSRIISLAQPKIRKDLNEGYNPYYISPASLVAQASPRIFELATPKYITKKV", "length": 380, "header": "tr|A0A8C2MKV3-1|A0A8C2MKV3_CRIGR Isoform 1 of Testicular haploid expressed gene protein isoform X1 OS=Cricetulus griseus OX=10029 GN=Theg PE=4 SV=1 CANONICAL=A0A8C2MKV3-1" }, "isoforms": [ { "isoform_ac": "A0A3L7HHU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MKV3/entry#A0A3L7HHU3-1", "sequence": { "sequence": "MGELGEHRASLLNNFVLEAKASGASGHGQSDTLGSGNMGLQSTTFESPWLQSSQATHAGLASEDTEEDVPPEEVPGEELLEIPNLDDRLRRELEVEVVEMSQLSISEPTPSISIARGRRKKSRRLMELAKPKTNWQCLRDRPSVYWTERFMEDTTLTITVPAVSRRVEELSRPKRFYLEYYNNNRTTPIWPIPRSTLEYQPSNRLKQLATPKVRNNIWSIDMSEISQVSRAAQTAVPTPRTLNLAKPRPPAILMEEWDPMPKPKPHVSDHNRLLQLATPKALSEKCVPDRNPQWEILDVTKKAVASSRIISLAQPKIRKDLNEGYNPYYISPASLVAQASPRIFELATPKYITKKV", "length": 356, "header": "tr|A0A3L7HHU3-1|A0A8C2MKV3_CRIGR Computationally mapped isoform of Testicular haploid expressed gene protein isoform X1 OS=Cricetulus griseus OX=10029 GN=Theg PE=4 SV=1 CANONICAL=A0A8C2MKV3-1" }, "locus": {} }, { "isoform_ac": "A0A8C2MKV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MKV3/entry#A0A8C2MKV3-1", "sequence": { "sequence": "MGELGEHRASLLNNFVLEAKASGASGHGQSDTLGSGNMGLQSTTFESPWLQSSQATHAGLASEDTEEDVPPEEVPGEELLEIPNLDDRLRRELEVEVVEMSQLSISEPTPSISIARGRRKKSRRLMELAKPKTNWQCLRDRTGCCCKGYAWISPHKSNLQFCLYWPSVYWTERFMEDTTLTITVPAVSRRVEELSRPKRFYLEYYNNNRTTPIWPIPRSTLEYQPSNRLKQLATPKVRNNIWSIDMSEISQVSRAAQTAVPTPRTLNLAKPRPPAILMEEWDPMPKPKPHVSDHNRLLQLATPKALSEKCVPDRNPQWEILDVTKKAVASSRIISLAQPKIRKDLNEGYNPYYISPASLVAQASPRIFELATPKYITKKV", "length": 380, "header": "tr|A0A8C2MKV3-1|A0A8C2MKV3_CRIGR Isoform 1 of Testicular haploid expressed gene protein isoform X1 OS=Cricetulus griseus OX=10029 GN=Theg PE=4 SV=1 CANONICAL=A0A8C2MKV3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HHU3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HHU3" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A3L7HHU3", "url": "https://www.uniprot.org/uniprotkb/A0A3L7HHU3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100760485", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100760485", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q9JMB1-1", "protein_name": "Sperm microtubule associated protein 2", "gene_name": "Spmap2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGELGEHRASLLSNPIPEVKTLGELKQGQNNGNLDLESEPFGSHWLQGSKATTGRTSEEPEEEIPPEEMAGEELPETSNLDGPLQQDLEVEVVEMSHLSITERTPSVSTAKGRKKRSRRLLELAKPKTNWQCLRDRTGRCCKGYAWISPRKTNLQFCLYWPSVYWTERFIEDTTLTITVPVVSQRMEELSRPKRFYQEYYNNNRTTPIWSIPRSTLEYQASNRLKQLATPKVRNNIWSINMSEVSQVSRAAQMAVPTPRTLRLAKPRPPATLLEEWDPMPKPKPYVSDYNRLLQLATPKALSEKCVPDRSPQWEVLDVTKNAVASSRIISLAQPKIRKDLNEGYNPYYISPASLVAQASPRIYELATPKYITKKV", "length": 375 }, "evidence": [ { "id": "A0A8C2MKV3", "url": "https://omabrowser.org/oma/group/A0A8C2MKV3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9P2T0-1", "protein_name": "Sperm microtubule associated protein 2", "gene_name": "SPMAP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDSRRRSLGNQPSSEAAGRSEREQDGDPRGLQSSVYESRRVTDPERQDLDNAELGPEDPEEELPPEEVAGEEFPETLDPKEALSELERVLDKDLEEDIPEISRLSISQKLPSTTMTKARKRRRRRRLMELAEPKINWQVLKDRKGRCGKGYAWISPCKMSLHFCLCWPSVYWTERFLEDTTLTITVPAVSRRVEELSRPKRFYLEYYNNNRTTPVWPIPRSSLEYRASSRLKELAAPKIRDNFWSMPMSEVSQVSRAAQMAVPSSRILQLSKPKAPATLLEEWDPVPKPKPHVSDHNRLLHLARPKAQSDKCVPDRDPRWEVLDVTKKVVASPRIISLAKPKVRKGLNEGYDRRPLASMSLPPPKASPEKCDQPRPGL", "length": 379 }, "evidence": [ { "id": "A0A8C2MKV3", "url": "https://omabrowser.org/oma/group/A0A8C2MKV3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2MKV3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2MKV3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 208, "end_pos": 210, "annotation": 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This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027257554", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027257554" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LV34", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LV34" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ssbp2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LV34", "locus": {} } ], "crossref": [ { "id": "100753364", "url": "https://www.ncbi.nlm.nih.gov/gene/100753364", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006594", "database": "InterPro", "categories": [ "Protein Classification" ] 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"MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKAFHDYSAAAAPSPVLGNMPPGDGMPVGPVPPGFFQPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPAMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPADSTNSGDNMYTLMNAVPPGPNRPNFPMGPASDGPMGGLGGMESHHMNGSLGSGDMDSISKNSPNNMSLSNQPGTPRDDGEMGGNFLNPFQSESYSPSMTMSV", "length": 361, "header": "tr|A0A8C2LV34-1|A0A8C2LV34_CRIGR Isoform 1 of Single-stranded DNA-binding protein 2 isoform X4 OS=Cricetulus griseus OX=10029 GN=Ssbp2 PE=4 SV=1 CANONICAL=A0A8C2LV34-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LUS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LV34/entry#A0A8C2LUS6-1", "sequence": { "sequence": "MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKAFHDYPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPAMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPADSTNSGDNMYTLMNAVPPGPNRPNFPMGPASDGPMGGLGGMESHHMNGSLGSGDMDSISKNSPNNMSLSNQPGTPRDDGEMGGNFLNPFQSESYSPSMTMSV", "length": 331, "header": "tr|A0A8C2LUS6-1|A0A8C2LV34_CRIGR Computationally mapped isoform of Single-stranded DNA-binding protein 2 isoform X4 OS=Cricetulus griseus OX=10029 GN=Ssbp2 PE=4 SV=1 CANONICAL=A0A8C2LV34-1" }, "locus": {} }, { "isoform_ac": "A0A8C2LV34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LV34/entry#A0A8C2LV34-1", "sequence": { "sequence": "MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKAFHDYSAAAAPSPVLGNMPPGDGMPVGPVPPGFFQPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPAMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPADSTNSGDNMYTLMNAVPPGPNRPNFPMGPASDGPMGGLGGMESHHMNGSLGSGDMDSISKNSPNNMSLSNQPGTPRDDGEMGGNFLNPFQSESYSPSMTMSV", "length": 361, "header": "tr|A0A8C2LV34-1|A0A8C2LV34_CRIGR Isoform 1 of Single-stranded DNA-binding protein 2 isoform X4 OS=Cricetulus griseus OX=10029 GN=Ssbp2 PE=4 SV=1 CANONICAL=A0A8C2LV34-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GUW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LV34/entry#A0A9J7GUW9-1", "sequence": { "sequence": "MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKAFHDYSAAAAPSPVLGNMPPGDGMPVGPVPPGFFQPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPAMNMGPGGGRPWPNPTNANSFPMGPASDGPMGGLGGMESHHMNGSLGSGDMDSISKNSPNNMSLSNQPGTPRDDGEMGGNFLNPFQSESYSPSMTMSV", "length": 307, "header": "tr|A0A9J7GUW9-1|A0A9J7GUW9_CRIGR Computationally mapped isoform of Single-stranded DNA-binding protein 2 isoform X6 OS=Cricetulus griseus OX=10029 GN=Ssbp2 PE=4 SV=1 CANONICAL=A0A8C2LV34-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LUS6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUS6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LUS6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUS6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100753364", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100753364", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LV34", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LV34" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LV34", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LV34" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "single-stranded DNA binding", "id": "GO:0003697", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003697", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LV34", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LV34" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 324, "end_pos": 326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": 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{ "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { 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"count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LUX2-1", "uniprot_ac": "A0A8C2LUX2", "uniprot_id": "A0A8C2LUX2_CRIGR", "mass": { "chemical_mass": 82987.0, "monoisotopic_mass": 82987.0 }, "refseq": { "ac": "XP_007650344", "name": "ribosomal RNA processing protein 1 homolog B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007650344" }, "gene_names": [ { "name": "Rrp1b", "type": "recommended", "evidence": [ { "id": "A0A8C2LUX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUX2" } ] }, { "name": "Rrp1b", "type": "synonym", "evidence": [ { "id": "XP_007650344", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007650344" } ] } ], "protein_names": [ { "name": "Ribosomal RNA processing protein 1 homolog B isoform X2", "type": "synonym", "evidence": [ { "id": "A0A8C2LUX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUX2/entry#names_and_taxonomy" } ] }, { "name": "ribosomal RNA processing protein 1 homolog B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007650344", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007650344" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 181 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003615174.1) and transcript sequence (IACG01177485.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007650344.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007650344", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007650344" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LUX2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUX2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rrp1b", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUX2", "locus": {} } ], "crossref": [ { "id": "100751493", "url": "https://www.ncbi.nlm.nih.gov/gene/100751493", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010301", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010301", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751493", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751493", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LUX2", "url": "https://www.orthodb.org/?gene=A0A8C2LUX2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13026", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13026", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13026:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13026:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05997", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05997", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007650344", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007650344", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LUX2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LUX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUX2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HBI8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7HBI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7HBI8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPAMQSAELQFAQRLASSEKGVRDRAVRKLRQYLSARTQSDTGGFSQEELLKIWKGLFYCMWVQDEPLLQEELANIISQLIHVVNSSEAQHLFIQTFWQTMNREWQGIDKLRLDKYYMLIRLVLRQSFEVLKRNAWEDSQVKLFLDILMKEILSPESQSPDGVKSHLIDIYLDELSAVGGRELLADQNLKLIDPFCRIAAKTKDHTLVQTIARGVFEVIVDQSAFVPEETVEEQKTKVGDGGLSAPEISANKLACRKAVGEKKPGLGECLKDGVVGGRERDGCAAFKDSGSPLQFDYKAVADRLLEIANLKSTPPFNRKRLCRLIRKFQDLSEGHSAQLSFGEDITVDENAQAIGQKRHKKKRKKLLERAALDREKGNAVSIDGEEDSGGNVHKRKRRKKKRNHFQAETQDPDAVTMPPAQGADGKPEAAQRQTPQACVTGPETEAVSGIRENSSEPAPITPTCNKRKRLRKKNLKVHREIWKSTPLPQEDMSENDPTHGHPQSADAQVSSSEGVRAQKRKRKLGALPVNSGGLTVQKAGTSTSPEEEKDDQTTLPQCKRPQKKTASSSLGLYDLSSQKTAILKKRKKMKQMSDLVEHNGVLESSTRQIQALGSNRTLKKPLTTEDDFVKFDTHFLPKPLFFRKAKSSSAISPQGSAVQMNITPSSSKKVTFGLNKNMTAEFRKTDKSILVSPTGLSRVAFNPEQRPLHGVLKTPTSSPASTPVSAMKLPATTPKRRPRAADFF", "length": 745, "header": "tr|A0A8C2LUX2-1|A0A8C2LUX2_CRIGR Isoform 1 of Ribosomal RNA processing protein 1 homolog B isoform X2 OS=Cricetulus griseus OX=10029 GN=Rrp1b PE=3 SV=1 CANONICAL=A0A8C2LUX2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LUX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUX2/entry#A0A8C2LUX2-1", "sequence": { "sequence": "MAPAMQSAELQFAQRLASSEKGVRDRAVRKLRQYLSARTQSDTGGFSQEELLKIWKGLFYCMWVQDEPLLQEELANIISQLIHVVNSSEAQHLFIQTFWQTMNREWQGIDKLRLDKYYMLIRLVLRQSFEVLKRNAWEDSQVKLFLDILMKEILSPESQSPDGVKSHLIDIYLDELSAVGGRELLADQNLKLIDPFCRIAAKTKDHTLVQTIARGVFEVIVDQSAFVPEETVEEQKTKVGDGGLSAPEISANKLACRKAVGEKKPGLGECLKDGVVGGRERDGCAAFKDSGSPLQFDYKAVADRLLEIANLKSTPPFNRKRLCRLIRKFQDLSEGHSAQLSFGEDITVDENAQAIGQKRHKKKRKKLLERAALDREKGNAVSIDGEEDSGGNVHKRKRRKKKRNHFQAETQDPDAVTMPPAQGADGKPEAAQRQTPQACVTGPETEAVSGIRENSSEPAPITPTCNKRKRLRKKNLKVHREIWKSTPLPQEDMSENDPTHGHPQSADAQVSSSEGVRAQKRKRKLGALPVNSGGLTVQKAGTSTSPEEEKDDQTTLPQCKRPQKKTASSSLGLYDLSSQKTAILKKRKKMKQMSDLVEHNGVLESSTRQIQALGSNRTLKKPLTTEDDFVKFDTHFLPKPLFFRKAKSSSAISPQGSAVQMNITPSSSKKVTFGLNKNMTAEFRKTDKSILVSPTGLSRVAFNPEQRPLHGVLKTPTSSPASTPVSAMKLPATTPKRRPRAADFF", "length": 745, "header": "tr|A0A8C2LUX2-1|A0A8C2LUX2_CRIGR Isoform 1 of Ribosomal RNA processing protein 1 homolog B isoform X2 OS=Cricetulus griseus OX=10029 GN=Rrp1b PE=3 SV=1 CANONICAL=A0A8C2LUX2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7HBI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUX2/entry#A0A9J7HBI8-1", "sequence": { "sequence": "MHVKVTAGGFSQEELLKIWKGLFYCMWVQDEPLLQEELANIISQLIHVVNSSEAQHLFIQTFWQTMNREWQGIDKLRLDKYYMLIRLVLRQSFEVLKRNAWEDSQVKLFLDILMKEILSPESQSPDGVKSHLIDIYLDELSAVGGRELLADQNLKLIDPFCRIAAKTKDHTLVQTIARGVFEVIVDQSAFVPEETVEEQKTKVGDGGLSAPEISANKLACRKAVGEKKPGLGECLKDGVVGGRERDGCAAFKDSGSPLQFDYKAVADRLLEIANLKSTPPFNRKRLCRLIRKFQDLSEGHSAQLSFGEDITVDENAQAIGQKRHKKKRKKLLERAALDREKGNAVSIDGEEDSGGNVHKRKRRKKKRNHFQAETQDPDAVTMPPAQGADGKPEAAQRQTPQACVTGPETEAVSGIRENSSEPAPITPTCNKRKRLRKKNLKVHREIWKSTPLPQEDMSENDPTHGHPQSADAQVSSSEGVRAQKRKRKLGALPVNSGGLTVQKAGTSTSPEEEKDDQTTLPQCKRPQKKTASSSLGLYDLSSQKTAILKKRKKMKQMSDLVEHNGVLESSTRQIQALGSNRTLKKPLTTEDDFVKFDTHFLPKPLFFRKAKSSSAISPQGSAVQMNITPSSSKKVTFGLNKNMTAEFRKTDKSILVSPTGLSRVAFNPEQRPLHGVLKTPTSSPASTPVSAMKLPATTPKRRPRAADFF", "length": 709, "header": "tr|A0A9J7HBI8-1|A0A9J7HBI8_CRIGR Computationally mapped isoform of Ribosomal RNA processing protein 1 homolog B isoform X3 OS=Cricetulus griseus OX=10029 GN=Rrp1b PE=3 SV=1 CANONICAL=A0A8C2LUX2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 462, "start_aa": "Thr", "end_pos": 462, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr462", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LUX2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUX2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LUX2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUX2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100751493", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751493", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LUX2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUX2" } ], "pmid": "" }, { "name": "preribosome, small subunit precursor", "id": "GO:0030688", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030688", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LUX2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUX2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LUX2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUX2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 454, "end_pos": 456, "annotation": "n_glycosylation_sequon" }, { "start_pos": 616, "end_pos": 618, "annotation": "n_glycosylation_sequon" }, { "start_pos": 662, "end_pos": 664, "annotation": "n_glycosylation_sequon" }, { "start_pos": 678, "end_pos": 680, "annotation": "n_glycosylation_sequon" }, { "start_pos": 86, "end_pos": 88, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 462 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 454, "end_pos": 456 }, { "start_pos": 616, "end_pos": 618 }, { "start_pos": 662, "end_pos": 664 }, { "start_pos": 678, "end_pos": 680 }, { "start_pos": 86, "end_pos": 88 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LUZ1-1", "uniprot_ac": "A0A8C2LUZ1", "uniprot_id": "A0A8C2LUZ1_CRIGR", "mass": { "chemical_mass": 45046.0, "monoisotopic_mass": 45046.0 }, "refseq": { "ac": "XP_027272954", "name": "golgin-45 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272954" }, "gene_names": [ { "name": "Blzf1", "type": "recommended", "evidence": [ { "id": "A0A8C2LUZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUZ1" } ] }, { "name": "Blzf1", "type": "synonym", "evidence": [ { "id": "XP_027272954", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272954" } ] } ], "protein_names": [ { "name": "Golgin-45 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8C2LUZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LUZ1/entry#names_and_taxonomy" } ] }, { "name": "golgin-45 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027272954", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027272954" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048598.1) annotated using gene prediction method: Gnomon. 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LVA2-1", "uniprot_ac": "A0A8C2LVA2", "uniprot_id": "A0A8C2LVA2_CRIGR", "mass": { "chemical_mass": 49654.0, "monoisotopic_mass": 49654.0 }, "refseq": { "ac": "XP_003515074", "name": "SPRY domain-containing protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003515074" }, "gene_names": [ { "name": "Spryd3", "type": "recommended", "evidence": [ { "id": "A0A8C2LVA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVA2" } ] }, { "name": "Spryd3", "type": "synonym", "evidence": [ { "id": "XP_003515074", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003515074" } ] } ], "protein_names": [ { "name": "SPRY domain-containing protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003515074", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003515074" }, { "id": "A0A8C2LVA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVA2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003617247.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003515074", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003515074" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LVA2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVA2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Spryd3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVA2", "locus": {} } ], "crossref": [ { "id": "cd12908", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12908", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100752094", "url": "https://www.ncbi.nlm.nih.gov/gene/100752094", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050618", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050618", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752094", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752094", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EEDDTMM", "url": "https://omabrowser.org/oma/group/EEDDTMM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LVA2", "url": "https://www.orthodb.org/?gene=A0A8C2LVA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7FAQ9", "url": "https://www.orthodb.org/?gene=A0A9J7FAQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12864", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12864", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003515074", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003515074", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LVA2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LVA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVA2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FAQ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FAQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FAQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FAQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRTRRPRFVLMNKMDDLNLHYRFLNWRRRIREIREVRAFRYQERFKHILVDGDTLSYHGNSGEVGCYVASRPLTKDSNYFEVSIVDSGVRGTIAVGLVPQYYSLDHQPGWLPDSVAYHADDGKLYNGRAKGRQFGSKCNSGDRIGCGIEPVSFDVQTAQIFFTKNGKRVGSTIMPMSPDGLFPAVGMHSLGEEVRLHLNAELGREDDSVMMVDSYEDEWGRLHDVRVCGTLLEYLGKGKSIVDVGLAQARHPLSTRSHYFEVEIVDPGEKCYIALGLARKDYPKNRHPGWSRGSVAYHADDGKIFHGSGVGDPFGPRCYKGDIMGCGIMFPRDYILDSEGDSDDSCDTVILSPTARAVRNVRNVMYLHQEGEEEEEEEEEEEEEEIEQEHEGKKVVVFFTRNGKIIGKKDAVVPSGGFFPTIGMLSCGEKVKVDLHPLSG", "length": 441, "header": "tr|A0A8C2LVA2-1|A0A8C2LVA2_CRIGR Isoform 1 of SPRY domain-containing protein 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Spryd3 PE=4 SV=1 CANONICAL=A0A8C2LVA2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LVA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVA2/entry#A0A8C2LVA2-1", "sequence": { "sequence": "MRRTRRPRFVLMNKMDDLNLHYRFLNWRRRIREIREVRAFRYQERFKHILVDGDTLSYHGNSGEVGCYVASRPLTKDSNYFEVSIVDSGVRGTIAVGLVPQYYSLDHQPGWLPDSVAYHADDGKLYNGRAKGRQFGSKCNSGDRIGCGIEPVSFDVQTAQIFFTKNGKRVGSTIMPMSPDGLFPAVGMHSLGEEVRLHLNAELGREDDSVMMVDSYEDEWGRLHDVRVCGTLLEYLGKGKSIVDVGLAQARHPLSTRSHYFEVEIVDPGEKCYIALGLARKDYPKNRHPGWSRGSVAYHADDGKIFHGSGVGDPFGPRCYKGDIMGCGIMFPRDYILDSEGDSDDSCDTVILSPTARAVRNVRNVMYLHQEGEEEEEEEEEEEEEEIEQEHEGKKVVVFFTRNGKIIGKKDAVVPSGGFFPTIGMLSCGEKVKVDLHPLSG", "length": 441, "header": "tr|A0A8C2LVA2-1|A0A8C2LVA2_CRIGR Isoform 1 of SPRY domain-containing protein 3 isoform X1 OS=Cricetulus griseus OX=10029 GN=Spryd3 PE=4 SV=1 CANONICAL=A0A8C2LVA2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FAQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVA2/entry#A0A9J7FAQ9-1", "sequence": { "sequence": "MNKMDDLNLHYRFLNWRRRIREIREVRAFRYQERFKHILVDGDTLSYHGNSGEVGCYVASRPLTKDSNYFEVSIVDSGVRGTIAVGLVPQYYSLDHQPGWLPDSVAYHADDGKLYNGRAKGRQFGSKCNSGDRIGCGIEPVSFDVQTAQIFFTKNGKRVGSTIMPMSPDGLFPAVGMHSLGEEVRLHLNAELGREDDSVMMVDSYEDEWGRLHDVRVCGTLLEYLGKGKSIVDVGLAQARHPLSTRSHYFEVEIVDPGEKCYIALGLARKDYPKNRHPGWSRGSVAYHADDGKIFHGSGVGDPFGPRCYKGDIMGCGIMFPRDYILDSEGDSDDSCDTVILSPTARAVRNVRNVMYLHQEGEEEEEEEEEEEEEEIEQEHEGKKVVVFFTRNGKIIGKKDAVVPSGGFFPTIGMLSCGEKVKVDLHPLSG", "length": 430, "header": "tr|A0A9J7FAQ9-1|A0A9J7FAQ9_CRIGR Computationally mapped isoform of SPRY domain-containing protein 3 isoform X2 OS=Cricetulus griseus OX=10029 GN=Spryd3 PE=4 SV=1 CANONICAL=A0A8C2LVA2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LVA2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVA2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LVA2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVA2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752094", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752094", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZWX7-1", "protein_name": "SPRY domain containing 3", "gene_name": "SPRYD3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRTRRPRFVLMNKMDDLNLHYRFLNWRRRIREIREVRAFRYQERFKHILVDGDTLSYHGNSGEVGCYVASRPLTKDSNYFEVSIVDSGVRGTIAVGLVPQYYSLDHQPGWLPDSVAYHADDGKLYNGRAKGRQFGSKCNSGDRIGCGIEPVSFDVQTAQIFFTKNGKRVGSTIMPMSPDGLFPAVGMHSLGEEVRLHLNAELGREDDSIMMVDSYEDEWGRLHDVRVCGTLLEYLGKGKSIVDVGLAQARHPLSTRSHYFEVEIVDPGEKCYIALGLARKDYPKNRHPGWSRGSVAYHADDGKIFHGSGVGDPFGPRCYKGDIMGCGIMFPRDYILDSEGDSDDSCDTVILSPTARAVRNVRNVMYLHQEGEEEEEEEEEEDDGEEIEQEHEGKKVVVFFTRNGKIIGKKDAVVPSGGFFPTIGMLSCGEKVKVDLHPLSG", "length": 442 }, "evidence": [ { "id": "A0A8C2LVA2", "url": "https://omabrowser.org/oma/group/A0A8C2LVA2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E9Q9B3-1", "protein_name": "SPRY domain containing 3", "gene_name": "Spryd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRRTRRPRFVLMNKMDDLNLHYRFLNWRRRIREIREVRAFRYQERFKHILVDGDTLSYHGNSGEVGCYVASRPLTKDSNYFEVSIVDSGVRGTIAVGLVPQYYSLDHQPGWLPDSVAYHADDGKLYNGRAKGRQFGSKCNSGDRIGCGIEPVSFDVQTAQIFFTKNGKRVGSTIMPMSPDGLFPAVGMHSLGEEVRLHLNAELGREDDSVMMVDSYEDEWGRLHDVRVCGTLLEYLGKGKSIVDVGLAQARHPLSTRSHYFEVEIVDPGEKCYIALGLARKDYPKNRHPGWSRGSVAYHADDGKIFHGSGVGDPFGPRCYKGDIMGCGIMFPRDYILDSEGDSDDSCDTVILSPTARAVRNVRNVMYLHQEGEEEEEEEEEEEDGEEIEQEHEGKKVVVFFTRNGKIIGKKDAVVPSGGFFPTIGMLSCGEKVKVDLHPLSG", "length": 442 }, "evidence": [ { "id": "A0A8C2LVA2", "url": "https://omabrowser.org/oma/group/A0A8C2LVA2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1M7P8-1", "protein_name": "SPRY domain containing 3", "gene_name": "Spryd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRRTRRPRFVLMNKMDDLNLHYRFLNWRRRIREIREVRAFRYQERFKHILVDGDTLSYHGNSGEVGCYVASRPLTKDSNYFEVSIVDSGVRGTIAVGLVPQYYSLDHQPGWLPDSVAYHADDGKLYNGRAKGRQFGSKCNSGDRIGCGIEPVSFDVQTAQIFFTKNGKRVGSTIMPMSPDGLFPAVGMHSLGEEVRLHLNAELGREDDSVMMVDSYEDEWGRLHDVRVCGTLLEYLGKGKSIVDVGLAQARHPLSTRSHYFEVEIVDPGEKCYIALGLARKDYPKNRHPGWSRGSVAYHADDGKIFHGSGVGDPFGPRCYKGDIMGCGIMFPRDYILDSEGDSDDSCDTVILSPTARAVRNVRNVMYLHQEGEEEEEEEEEEEDGEEIEQEHEGKKVVVFFTRNGKIIGKKDAVVPSGGFFPTIGMLSCGEKVKVDLHPLSG", "length": 442 }, "evidence": [ { "id": "A0A8C2LVA2", "url": "https://omabrowser.org/oma/group/A0A8C2LVA2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8NCJ5-1", "protein_name": "SPRY domain-containing protein 3", "gene_name": "SPRYD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRRTRRPRFVLMNKMDDLNLHYRFLNWRRRIREIREVRAFRYQERFKHILVDGDTLSYHGNSGEVGCYVASRPLTKDSNYFEVSIVDSGVRGTIAVGLVPQYYSLDHQPGWLPDSVAYHADDGKLYNGRAKGRQFGSKCNSGDRIGCGIEPVSFDVQTAQIFFTKNGKRVGSTIMPMSPDGLFPAVGMHSLGEEVRLHLNAELGREDDSVMMVDSYEDEWGRLHDVRVCGTLLEYLGKGKSIVDVGLAQARHPLSTRSHYFEVEIVDPGEKCYIALGLARKDYPKNRHPGWSRGSVAYHADDGKIFHGSGVGDPFGPRCYKGDIMGCGIMFPRDYILDSEGDSDDSCDTVILSPTARAVRNVRNVMYLHQEGEEEEEEEEEEEDGEEIEPEHEGRKVVVFFTRNGKIIGKKDAVVPSGGFFPTIGMLSCGEKVKVDLHPLSG", "length": 442 }, "evidence": [ { "id": "A0A8C2LVA2", "url": "https://omabrowser.org/oma/group/A0A8C2LVA2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LVA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVA2" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 17, "end_pos": 204, "start_aa": "Asp", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { 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"MAMTLLEDWCRGMDVNSQRALLVWGIPVNCDETEIEETLQAAMPQVSYRVLGRMFWREENAKAALLELTGAVDYSLIPREMPGKGGLWKVVFKPPTSDAVFLERLHLFLAREGWTVQDVARVLGFQNPAPAPGPEMPAEMLNYILDNVIQPLVESIWYKKLTLFSGKDIPGPGEETFDSWLEHSNEIIEEWQVSDIEKRRRLMESLRGPAADVIRILKTNNAAITTAECLKALEQVFGSVESSRDAQVRFLNTYQNPGEKLSSYVIRLEPLLQKVVDKGVIDKDNVNQARLEQVIAGANHSGALRRQLWLAGAEEGPAPNLFQLLVQIREEEAKKEEEEAEAALLQLGLEGHF", "length": 353 }, "evidence": [ { "id": "A0A8C2LVI2", "url": "https://omabrowser.org/oma/group/A0A8C2LVI2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8ND90-1", "protein_name": "Paraneoplastic antigen Ma1", "gene_name": "PNMA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"MAMTLLEDWCRGMDVNSQRALLVWGIPVNCDETEIEETLQAAMPQVSYRVLGRMFWREENAKAALLELTGTVDYSLIPREMPGKGGLWKVVFKPPTSDAEFLERLHLFLAREGWTVQDVARVLGFQNPAPAPGPEMPAEMLNYILDNVIQPLVESIWYKKLTLFSGRDIPGPGEETFDSWLEHSNEVIEEWQVSDIEKRRRLMESLRGPAADVIRILKTNNPAITTAECLKALEQVFGSVESSRDAQVRFLNTYQNPGEKLSSYVIRLEPLLQKVVDKGAIDKDNVNQARLEQVIAGANHSGALRRQLWLTGATEGPAPNLFQLLVQIREEEAKEEEEEAEAALLQLGLEGHF", "length": 353 }, "evidence": [ { "id": "A0A8C2LVI2", "url": "https://omabrowser.org/oma/group/A0A8C2LVI2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LVI2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVI2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LVI2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVI2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 299, "end_pos": 301, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LVI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVI2" }, { "id": "PF14893", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14893" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Paraneoplastic antigen Ma-like C-terminal", "eco_id": "ECO_0000259", "start_pos": 164, "end_pos": 325, "start_aa": "Phe", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2LVI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVI2" }, { "id": "PF20846", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20846" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Paraneoplastic antigen Ma-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 90, "start_aa": "Met", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 299, "end_pos": 301 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LVK5-1", "uniprot_ac": "A0A8C2LVK5", "uniprot_id": "A0A8C2LVK5_CRIGR", "mass": { "chemical_mass": 9801.0, "monoisotopic_mass": 9801.0 }, "refseq": { "ac": "XP_035307592", "name": "late cornified envelope protein 3D-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307592" }, "gene_names": [ { "name": "LOC100757718", "type": "recommended", "evidence": [ { "id": "A0A8C2LVK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVK5" } ] }, { "name": "LOC100757718", "type": "synonym", "evidence": [ { "id": "XP_035307592", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307592" } ] } ], "protein_names": [ { "name": "Late cornified envelope protein 3D-like", "type": "synonym", "evidence": [ { "id": "A0A8C2LVK5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVK5/entry#names_and_taxonomy" } ] }, { "name": "late cornified envelope protein 3D-like", "type": "synonym", "evidence": [ { "id": "XP_035307592", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307592" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035307592", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307592" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LVK5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVK5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100757718", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVK5", "locus": {} } ], "crossref": [ { "id": "100757718", "url": "https://www.ncbi.nlm.nih.gov/gene/100757718", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028205", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028205", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100757718", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757718", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CCRSHRC", "url": "https://omabrowser.org/oma/group/CCRSHRC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PF14672", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14672", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035307592", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035307592", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LVK5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LVK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVK5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSCQQNQKQCQPPPKCPSPKCPPKSTAQCLPAASSCCATSSGGCSVPSSEGGCFLSHHRRRSHRCRHRSSSRSCDRGSGQQSGSSGCGHSSGGCC", "length": 95, "header": "tr|A0A8C2LVK5-1|A0A8C2LVK5_CRIGR Isoform 1 of Late cornified envelope protein 3D-like OS=Cricetulus griseus OX=10029 GN=LOC100757718 PE=3 SV=1 CANONICAL=A0A8C2LVK5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LVK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVK5/entry#A0A8C2LVK5-1", "sequence": { "sequence": "MSCQQNQKQCQPPPKCPSPKCPPKSTAQCLPAASSCCATSSGGCSVPSSEGGCFLSHHRRRSHRCRHRSSSRSCDRGSGQQSGSSGCGHSSGGCC", "length": 95, "header": "tr|A0A8C2LVK5-1|A0A8C2LVK5_CRIGR Isoform 1 of Late cornified envelope protein 3D-like OS=Cricetulus griseus OX=10029 GN=LOC100757718 PE=3 SV=1 CANONICAL=A0A8C2LVK5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LVK5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVK5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LVK5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVK5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100757718", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100757718", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5Y4Y7-1", "protein_name": "Late cornified envelope 3D", "gene_name": "Lce3d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSCQQSQKQCQPPPKCPSPKCSPKCPPKSTAQCLPAASSCCATSSGGCSVPSSEGGCCLSHHRRRSHRCRRRSSSSCDRGSGQQSGGSGCGHTSGGCC", "length": 98 }, "evidence": [ { "id": "A0A8C2LVK5", "url": "https://omabrowser.org/oma/group/A0A8C2LVK5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8W4FPF4-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC100152299", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSCQQNQQQCQPPPKCPSPKCPPKSPAHCWPPASSSGCAPISGGCGGPSSEGGCCLSPHRRRRSHRCRLLSSDSCDGGSGLQSGGSGCGQGSGGCC", "length": 96 }, "evidence": [ { "id": "A0A8C2LVK5", "url": "https://omabrowser.org/oma/group/A0A8C2LVK5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5TA77-1", "protein_name": "Late cornified envelope protein 3B", "gene_name": "LCE3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSCQQNQQQCQPLPKCPSPKCPPKSSAQCLPPASSCCAPRPGCCGGPSSEGGCCLSHHRCCRSHRCRRQSSNSCDRGSGQQDGASDCGYGSGGCC", "length": 95 }, "evidence": [ { "id": "A0A8C2LVK5", "url": "https://omabrowser.org/oma/group/A0A8C2LVK5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91V05-1", "protein_name": "Late cornified envelope 3C", "gene_name": "Lce3c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCQQSQKQCQPPPKCPSPKCSPKCPPKSTAQCLPAASSCCATSSGGCSLPSSEGGCCLSHHRRRSHRCRRRSSSSCDRGSGQQSGGSGCGHSSGGCC", "length": 98 }, "evidence": [ { "id": "A0A8C2LVK5", "url": "https://omabrowser.org/oma/group/A0A8C2LVK5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "keratinization", "id": "GO:0031424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031424", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LVK5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVK5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LVN3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVN3" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100764743", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100764743", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LVN3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVN3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LVN3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVN3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LVN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVN3" }, { "id": "PS50904", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50904" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PRELI/MSF1", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 174, "start_aa": "Val", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 154, "end_pos": 156 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LVP7-1", "uniprot_ac": "A0A8C2LVP7", "uniprot_id": "A0A8C2LVP7_CRIGR", "mass": { "chemical_mass": 64751.0, "monoisotopic_mass": 64751.0 }, "refseq": { "ac": "XP_035294750", "name": "protein THEMIS3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294750" }, "gene_names": [ { "name": "LOC100763208", "type": "recommended", "evidence": [ { "id": "A0A8C2LVP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVP7" } ] }, { "name": "LOC100763208", "type": "synonym", "evidence": [ { "id": "XP_035294750", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294750" } ] } ], "protein_names": [ { "name": "Protein THEMIS3", "type": "synonym", "evidence": [ { "id": "A0A8C2LVP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVP7/entry#names_and_taxonomy" } ] }, { "name": "protein THEMIS3", "type": "synonym", "evidence": [ { "id": "XP_035294750", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294750" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035294750", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294750" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LVP7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVP7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100763208", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVP7", "locus": {} } ], "crossref": [ { "id": "100763208", "url": "https://www.ncbi.nlm.nih.gov/gene/100763208", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100763208", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763208", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MRQIYSM", "url": "https://omabrowser.org/oma/group/MRQIYSM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LVP7", "url": "https://www.orthodb.org/?gene=A0A8C2LVP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15215", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15215", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15215:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15215:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12736", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12736", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035294750", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294750", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LVP7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LVP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVP7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQTWGSYINSLNQNSLPRQVEVTDGKYFSGSLNNMSFSRGDIITVVDLKPIHVRAEVKDGEQVLGMVNIPLGYKGNFQLIADPVAFETVADLVRSVRLPQSPMTHRCPPHFQNLVPISMDDGPTKLRSGETLSLVGFAESQGRRLLQCEVLRKDPPLRLLLPMDCRGRFQECQDHQLYSIDTIVRWKLLAGRQRRVRMEAGHRLRLLNPLVPERFNGHLVLHPHFSVVAHLPGAIQVSIPSDLDIHITEIACLDHKPFTLTTMRQIYSMEPNRFPVRIKVMSVTLSENKALTKPLKCGQRLTILRAEDVKKFVATEISQGRKGRRFLIPYTYQGLVLRRGRYFYAVSDVAAAMQQGQLCFQSCRDYSSCLEPLASFTANESFLALKKSVVSAEMHGELHRVEVLKCLNIATKAQVKLPLFAEGDFRELFADAGPGTLWELCQVTKLPCHIRVLSPDRSMARDPLHGTEELRIENIVVEQCLVAKDEAFLEDVDASVDIYREWPETTFEIPVEKSNCEVVVLEERSWMADVGKERCESLQSVQEITEEELLAFSNCAVIPCPPPPLPKPRSLS", "length": 573, "header": "tr|A0A8C2LVP7-1|A0A8C2LVP7_CRIGR Isoform 1 of Protein THEMIS3 OS=Cricetulus griseus OX=10029 GN=LOC100763208 PE=3 SV=1 CANONICAL=A0A8C2LVP7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LVP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVP7/entry#A0A8C2LVP7-1", "sequence": { "sequence": "MEQTWGSYINSLNQNSLPRQVEVTDGKYFSGSLNNMSFSRGDIITVVDLKPIHVRAEVKDGEQVLGMVNIPLGYKGNFQLIADPVAFETVADLVRSVRLPQSPMTHRCPPHFQNLVPISMDDGPTKLRSGETLSLVGFAESQGRRLLQCEVLRKDPPLRLLLPMDCRGRFQECQDHQLYSIDTIVRWKLLAGRQRRVRMEAGHRLRLLNPLVPERFNGHLVLHPHFSVVAHLPGAIQVSIPSDLDIHITEIACLDHKPFTLTTMRQIYSMEPNRFPVRIKVMSVTLSENKALTKPLKCGQRLTILRAEDVKKFVATEISQGRKGRRFLIPYTYQGLVLRRGRYFYAVSDVAAAMQQGQLCFQSCRDYSSCLEPLASFTANESFLALKKSVVSAEMHGELHRVEVLKCLNIATKAQVKLPLFAEGDFRELFADAGPGTLWELCQVTKLPCHIRVLSPDRSMARDPLHGTEELRIENIVVEQCLVAKDEAFLEDVDASVDIYREWPETTFEIPVEKSNCEVVVLEERSWMADVGKERCESLQSVQEITEEELLAFSNCAVIPCPPPPLPKPRSLS", "length": 573, "header": "tr|A0A8C2LVP7-1|A0A8C2LVP7_CRIGR Isoform 1 of Protein THEMIS3 OS=Cricetulus griseus OX=10029 GN=LOC100763208 PE=3 SV=1 CANONICAL=A0A8C2LVP7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LVP7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVP7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LVP7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVP7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100763208", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100763208", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A8M8-1", "protein_name": "Thymocyte selection associated family member 3", "gene_name": "Themis3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEQTWDSYINSLNRNSLPRQVEVTEGNYFSGSLENLSFSKGDVITVVDLEPILVRAEVKDGERVLDLVDIPLGYEGNFQLVADPVSFETVADLIHSVRLPQNPVAHRSPPRFQNLIPISTDDVPMKLRKGETLSLIGFEESQGRRLLRCEVLRKTPPLKLLLPMDCRGHFLECQDDQLYSIDTIVRWKLLAGRKRRVRVQAGHRLRLLSPLVPEHFRGHLVLHPYFSVMAYLPGETQVSIPSDLDISVTEITGLDRKPRTTMRQIFSMEENKFPVRIKITSVVLTENEVCPKPLKCGQLLTILRTENVRKFVATEISQGKKGRRFLIPYTYQGLVHRRGRYFYAVSDVAAAMQHGQVYFQASRDYTSFLGPSASFEADECFLALKKTVVFAKFHSELHRVKVLKCLNIATKDQVKLPLFAVGEFLELFDGAGPGTLQELCQVTKLPCHVSVASPDPSVTEEEEDPLYGTEELRIENVVVERCLIAKDEPSLEDMIASGDIYRECPEATFAIPIEKSSFEVSVVEEPSWIADVEKEKCTPLQSIQEVTEKSLAFSNCLVIPRPPPLAPKPRSLF", "length": 573 }, "evidence": [ { "id": "A0A8C2LVP7", "url": "https://omabrowser.org/oma/group/A0A8C2LVP7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9CU24-1", "protein_name": "Protein THEMIS3", "gene_name": "Themis3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEQTWDSYISSLNQNSLPRQVEVTQGRYSGSLENLSFSKGDIITVVDLEPVFVRAELKDGDQVLDVVTIPLRYEGNFQLMADPVSFETVADLTRSVRLPQSPVAPRSPPRFQNSIPISADNLPMKLRKGETLSLIGFQESRGRRLLQCKVLRKKPPLTVLLPMDCRGHFLECQDDRFYSIDTIVRWKMLAGRKRTVRVQARHHPKLLGPLVPEHFRGHLVLYPCFSVTANLLGETRVSIPSDLDISVTEIARLDRKPRTTMRQIYSMEESKFPVRVKIMNVVQSESKEYPKPLKRGQLLTILKTEEVKKFVASEISQGKKGKCFLVPYTYQGLVLRRGRYFYAVSDVAAAMKHGELCFQASQDYTSYLGSFASFRANECFLALKKSVVSAEIHGELHRVEVLKCLNIATKAHVKLPLFAVGKFLELFDGARPGTLQELCQVTRLPCHVRVTSPDPSMTVDPLYGTKELRIENVIIEQCLIAKDEPTLEDIISSADMYREWPETTFEIPIEKISCEVLVVEERSWIADVRKERCRPLQSIQEVTKESLAFSNCLVIRRPPPPVPKPRSLF", "length": 569 }, "evidence": [ { "id": "A0A8C2LVP7", "url": "https://omabrowser.org/oma/group/A0A8C2LVP7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": 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"https://www.ncbi.nlm.nih.gov/protein/XP_003502089" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613875.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_003502089.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003502089", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502089" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LVR0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100754310", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR0", "locus": {} } ], "crossref": [ { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100754310", "url": "https://www.ncbi.nlm.nih.gov/gene/100754310", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100754310", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100754310", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HQLYDNQ", "url": "https://omabrowser.org/oma/group/HQLYDNQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LVR0", "url": "https://www.orthodb.org/?gene=A0A8C2LVR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24271", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24271", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24271:SF81", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24271:SF81", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003502089", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502089", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LVR0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LVR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKFLLLLLALSLPPGTNAGEIIGGHEAKPHSRPYMAYLQFMDRDSQRRCGGFLIREDFVLTAAHCSGSSINVTLGAHNIKAKEETQQLIPVAKAIPHPDYNHNDYSNDIMLLKLKWKARRTNAVRPLVLPSRRGVHVKPGDMCYVAGWGRTAVKGKCSNTLQEVELTVQKDQECEARYPNCYNKATEICVGDPKINRAAFRGDSGGPLVCKKVAAGILSFGKEDSSTPIAFMRVSSFLPWIKKTMKRN", "length": 248, "header": "tr|A0A8C2LVR0-1|A0A8C2LVR0_CRIGR Isoform 1 of Granzyme B-like OS=Cricetulus griseus OX=10029 GN=LOC100754310 PE=4 SV=1 CANONICAL=A0A8C2LVR0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LVR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR0/entry#A0A8C2LVR0-1", "sequence": { "sequence": "MKFLLLLLALSLPPGTNAGEIIGGHEAKPHSRPYMAYLQFMDRDSQRRCGGFLIREDFVLTAAHCSGSSINVTLGAHNIKAKEETQQLIPVAKAIPHPDYNHNDYSNDIMLLKLKWKARRTNAVRPLVLPSRRGVHVKPGDMCYVAGWGRTAVKGKCSNTLQEVELTVQKDQECEARYPNCYNKATEICVGDPKINRAAFRGDSGGPLVCKKVAAGILSFGKEDSSTPIAFMRVSSFLPWIKKTMKRN", "length": 248, "header": "tr|A0A8C2LVR0-1|A0A8C2LVR0_CRIGR Isoform 1 of Granzyme B-like OS=Cricetulus griseus OX=10029 GN=LOC100754310 PE=4 SV=1 CANONICAL=A0A8C2LVR0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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{ "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LVR8-1", "uniprot_ac": "A0A8C2LVR8", "uniprot_id": "A0A8C2LVR8_CRIGR", "mass": { "chemical_mass": 278681.0, "monoisotopic_mass": 278681.0 }, "refseq": { "ac": "XP_003501208", "name": "centrosome-associated protein CEP250 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501208" }, "gene_names": [ { "name": "Cep250", "type": "recommended", "evidence": [ { "id": "A0A8C2LVR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR8" } ] }, { "name": "Cep250", "type": "synonym", "evidence": [ { "id": "XP_003501208", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501208" } ] } ], "protein_names": [ { "name": "Centrosome-associated protein CEP250 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8C2LVR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR8/entry#names_and_taxonomy" } ] }, { "name": "centrosome-associated protein CEP250 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003501208", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501208" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613833.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003501208", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501208" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LVR8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cep250", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR8", "locus": {} } ], "crossref": [ { "id": "100762321", "url": "https://www.ncbi.nlm.nih.gov/gene/100762321", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR055167", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055167", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057658", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057658", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762321", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762321", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DQDLRHQ", "url": "https://omabrowser.org/oma/group/DQDLRHQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LVR8", "url": "https://www.orthodb.org/?gene=A0A8C2LVR8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JTI4", "url": "https://www.orthodb.org/?gene=A0A9J7JTI4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JUX2", "url": "https://www.orthodb.org/?gene=A0A9J7JUX2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23159", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23159", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23159:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23159:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15035", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15035", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25774", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25774", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003501208", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501208", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LVR8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LVR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZY7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZY7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H174", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H174", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H174-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H174-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1Z7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1Z7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1Z7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JTI4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JTI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JTI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JUX2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JUX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JUX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JUX2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METGSPGLNMKPKSLQLVLEEQVLALQHQMAENQAASWQKLKNSQEAQKRQATLVRKLQAKVLQYRSWCQELEKRLEATGGLIPQRWEGVEEPNLEQLLVRLEEEQQRCESLVEVNTELRLHMEKADVVNKALREDVEKLTVDWSRARDELIRKESQWRLEQEFFKGYLKGEHDRLLNLWREVVTFRRHFLKMKSATDRDLTELKAEHAKLSGSLLTCCLRLTVRAQSRESSGSGRTENEPAQLLLLVAKTQALEKEAHEKSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMVKALRETMETLETNHAELMEHEVSLSRNAQEEMLSLQHVIKDIAQVLASVEEEDTVTHSSDHESSLQLDCSGFSPFDPQNPDKALTLVRSVLTRRQQAVQDLRQQLSGCQEAMSFLQQQHRQWEEEGEALRERLHKLTGERDALAGQTVDLQGEVDSLSKERELLQKARGELQEQLEVLEQEAWRLRRVNMELQLQGDSAQGEKQEQQEELHMAVRERELLQEMLVSLEAKQSESLSELMTLREALESSRLEGELLRQEQVEVTAAWARAEQSIAELSASENSLKAEVADLRAAAVKLGALNEALALDKVGLNQQLLQLEQENQSVCSRAEAAEHLRSALQVDLAEAERHREALWEKNTQLQTQLQKAEESGAELQAELKSIREEKEELKEKLSEAHHQQEAATAQLEQLHQDTERQQETLARAVQEKETLVRERATLEVRLQAVERDRQDLTEQVLGLRSAKEQLESNLFETQQQNSVIEVTKGQLEIQVQTITQAKEVIQGEVKCLKLELDAERSRAEQERDAVARQLAQAEQEGQAALEQQKVAHEEELNRLQEKWEKERSLLQQELEKALETLERERTELEVRLREQQTETEALRAQREEERTHADSTLYQMQLETEKERVSLLETLLQTQKELADATQQLERLRKDMKIQKLQEQETTDMLQTQLQGAQQELKEATQQHSEEHAAFRKDREDLQKQVEDLKSQLVTQDDSHRLVKQEIQEKMKEVQEYSRIQKELEKEKASLALSLVEKEGRLLILQEADSVRQQELNSLRQDIQEAQEGQRELSVQVELLRQEVKEKEADFVAREAQLLEELEASRITEQQLRASLWTQEAKTTQLQLQLRSTESQLEVLAAEQQPENQAQAQLASLYSVLQQALGSACESRPELRGGGDSAPSLWGPEPDQNGARRPFKRGSLLTALSAEAVALALQKLHQDLWKAQQARDDLRDQIQKLKQHLTDTEAQKSQVHSDLQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETVASLQSRLRQAELQKMEAQNEQELLQASKEKLTAQVERLQAFVAEAHAQASAASVLEEDLRTARSALKLKNEEVESERERAQALQEQSELKVAQGKALQENLALLAQTLSNREREVETLQTEIQELEKQREMQKAALELLSLDLKQRSQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQQLSVQQDQIRELEKDRETQRSVLEHQLLELEKKAQVIESQRGQIQDLKKQLVTLECLALELEESHHKVEGQQQVIAELESQREMQRVALTHLTLDLEERSQDLQAQSSQLHELESHGTHLARELQERDQEVKAQRQQIEELQKQKEQLTQDLERKGQELMLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQEMASQRQLMLERADNGQSPGKAQRGSLEHLKLILREKEKEVECQHERIQELEEHVGQVEQQLQGLHRKMGETSLLLTHREQEVATLQRHLQEAKDQGELKEQALQGQLEEAQRALAQRDQELEALQQEQQQTLAQEESMKQKTGALQAALEQAQVTLKERQGELEEHRERAQRLQEELVLEGRQVRALEEVLADLRSEIREHEKAVLALQQQCAEQAQEHEAEARTLQDSWLRAQATLSEQEQELAALRAENQYSRHQEEAAWGQAEALQEALSKAQAALQDKEQSLLEQAELSCTLEASTTALQASLDNCQSRARQLEEALKIREGEIQAQGLQHQEVTQQLQQALSQKEEKLRQQEEQRQLLEKALTQSSQENGIQEKQSLEQERKEDTGGLVASLRELQRTLAQKEEEILMLREAQQRQSLEASSPSHRAFPAEKPAPQLCQELERLQNALRQTEAREIEWREKAQDLARSLAQSKASNNSLQEIAMLLQASVLERESEQQRLQEELVLSRQALEEQQSHGSHSTSRADRGPKAGQDVHPGKVVVAEPSPGVEEKEQWTQRLERLQQAVAQLEFDRSKLQHHNAQLRITLELVERERRKLKRDSMRASRAGSLEMKEAMASSPAQQDGRAAQRGSSDSMRVVELQREVALLRAQLALERKQRQDYIARSVQTSRELAGLHHSLSHSLLTVAQAPEATVLEAETRKLDESLSQSLASPEPVLLHPSLDTAQTTPR", "length": 2425, "header": "tr|A0A8C2LVR8-1|A0A8C2LVR8_CRIGR Isoform 1 of Centrosome-associated protein CEP250 isoform X1 OS=Cricetulus griseus OX=10029 GN=Cep250 PE=4 SV=1 CANONICAL=A0A8C2LVR8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LVR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR8/entry#A0A8C2LVR8-1", "sequence": { "sequence": "METGSPGLNMKPKSLQLVLEEQVLALQHQMAENQAASWQKLKNSQEAQKRQATLVRKLQAKVLQYRSWCQELEKRLEATGGLIPQRWEGVEEPNLEQLLVRLEEEQQRCESLVEVNTELRLHMEKADVVNKALREDVEKLTVDWSRARDELIRKESQWRLEQEFFKGYLKGEHDRLLNLWREVVTFRRHFLKMKSATDRDLTELKAEHAKLSGSLLTCCLRLTVRAQSRESSGSGRTENEPAQLLLLVAKTQALEKEAHEKSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMVKALRETMETLETNHAELMEHEVSLSRNAQEEMLSLQHVIKDIAQVLASVEEEDTVTHSSDHESSLQLDCSGFSPFDPQNPDKALTLVRSVLTRRQQAVQDLRQQLSGCQEAMSFLQQQHRQWEEEGEALRERLHKLTGERDALAGQTVDLQGEVDSLSKERELLQKARGELQEQLEVLEQEAWRLRRVNMELQLQGDSAQGEKQEQQEELHMAVRERELLQEMLVSLEAKQSESLSELMTLREALESSRLEGELLRQEQVEVTAAWARAEQSIAELSASENSLKAEVADLRAAAVKLGALNEALALDKVGLNQQLLQLEQENQSVCSRAEAAEHLRSALQVDLAEAERHREALWEKNTQLQTQLQKAEESGAELQAELKSIREEKEELKEKLSEAHHQQEAATAQLEQLHQDTERQQETLARAVQEKETLVRERATLEVRLQAVERDRQDLTEQVLGLRSAKEQLESNLFETQQQNSVIEVTKGQLEIQVQTITQAKEVIQGEVKCLKLELDAERSRAEQERDAVARQLAQAEQEGQAALEQQKVAHEEELNRLQEKWEKERSLLQQELEKALETLERERTELEVRLREQQTETEALRAQREEERTHADSTLYQMQLETEKERVSLLETLLQTQKELADATQQLERLRKDMKIQKLQEQETTDMLQTQLQGAQQELKEATQQHSEEHAAFRKDREDLQKQVEDLKSQLVTQDDSHRLVKQEIQEKMKEVQEYSRIQKELEKEKASLALSLVEKEGRLLILQEADSVRQQELNSLRQDIQEAQEGQRELSVQVELLRQEVKEKEADFVAREAQLLEELEASRITEQQLRASLWTQEAKTTQLQLQLRSTESQLEVLAAEQQPENQAQAQLASLYSVLQQALGSACESRPELRGGGDSAPSLWGPEPDQNGARRPFKRGSLLTALSAEAVALALQKLHQDLWKAQQARDDLRDQIQKLKQHLTDTEAQKSQVHSDLQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETVASLQSRLRQAELQKMEAQNEQELLQASKEKLTAQVERLQAFVAEAHAQASAASVLEEDLRTARSALKLKNEEVESERERAQALQEQSELKVAQGKALQENLALLAQTLSNREREVETLQTEIQELEKQREMQKAALELLSLDLKQRSQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQQLSVQQDQIRELEKDRETQRSVLEHQLLELEKKAQVIESQRGQIQDLKKQLVTLECLALELEESHHKVEGQQQVIAELESQREMQRVALTHLTLDLEERSQDLQAQSSQLHELESHGTHLARELQERDQEVKAQRQQIEELQKQKEQLTQDLERKGQELMLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQEMASQRQLMLERADNGQSPGKAQRGSLEHLKLILREKEKEVECQHERIQELEEHVGQVEQQLQGLHRKMGETSLLLTHREQEVATLQRHLQEAKDQGELKEQALQGQLEEAQRALAQRDQELEALQQEQQQTLAQEESMKQKTGALQAALEQAQVTLKERQGELEEHRERAQRLQEELVLEGRQVRALEEVLADLRSEIREHEKAVLALQQQCAEQAQEHEAEARTLQDSWLRAQATLSEQEQELAALRAENQYSRHQEEAAWGQAEALQEALSKAQAALQDKEQSLLEQAELSCTLEASTTALQASLDNCQSRARQLEEALKIREGEIQAQGLQHQEVTQQLQQALSQKEEKLRQQEEQRQLLEKALTQSSQENGIQEKQSLEQERKEDTGGLVASLRELQRTLAQKEEEILMLREAQQRQSLEASSPSHRAFPAEKPAPQLCQELERLQNALRQTEAREIEWREKAQDLARSLAQSKASNNSLQEIAMLLQASVLERESEQQRLQEELVLSRQALEEQQSHGSHSTSRADRGPKAGQDVHPGKVVVAEPSPGVEEKEQWTQRLERLQQAVAQLEFDRSKLQHHNAQLRITLELVERERRKLKRDSMRASRAGSLEMKEAMASSPAQQDGRAAQRGSSDSMRVVELQREVALLRAQLALERKQRQDYIARSVQTSRELAGLHHSLSHSLLTVAQAPEATVLEAETRKLDESLSQSLASPEPVLLHPSLDTAQTTPR", "length": 2425, "header": "tr|A0A8C2LVR8-1|A0A8C2LVR8_CRIGR Isoform 1 of Centrosome-associated protein CEP250 isoform X1 OS=Cricetulus griseus OX=10029 GN=Cep250 PE=4 SV=1 CANONICAL=A0A8C2LVR8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GZY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR8/entry#A0A9J7GZY7-1", "sequence": { "sequence": "MVKALRETMETLETNHAELMEHEVSLSRNAQEEMLSLQHVIKDIAQVLASVEEEDTVTHSSDHESSLQLDCSGFSPFDPQNPDKALTLVRSVLTRRQQAVQDLRQQLSGCQEAMSFLQQQHRQWEEEGEALRERLHKLTGERDALAGQTVDLQGEVDSLSKERELLQKARGELQEQLEVLEQEAWRLRRVNMELQLQGDSAQGEKQEQQEELHMAVRERELLQEMLVSLEAKQSESLSELMTLREALESSRLEGELLRQEQVEVTAAWARAEQSIAELSASENSLKAEVADLRAAAVKLGALNEALALDKVGLNQQLLQLEQENQSVCSRAEAAEHLRSALQVDLAEAERHREALWEKNTQLQTQLQKAEESGAELQAELKSIREEKEELKEKLSEAHHQQEAATAQLEQLHQDTERQQETLARAVQEKETLVRERATLEVRLQAVERDRQDLTEQVLGLRSAKEQLESNLFETQQQNSVIEVTKGQLEIQVQTITQAKEVIQGEVKCLKLELDAERSRAEQERDAVARQLAQAEQEGQAALEQQKVAHEEELNRLQEKWEKERSLLQQELEKALETLERERTELEVRLREQQTETEALRAQREEERTHADSTLYQMQLETEKERVSLLETLLQTQKELADATQQLERLRKDMKIQKLQEQETTDMLQTQLQGAQQELKEATQQHSEEHAAFRKDREDLQKQVEDLKSQLVTQDDSHRLVKQEIQEKMKEVQEYSRIQKELEKEKASLALSLVEKEGRLLILQEADSVRQQELNSLRQDIQEAQEGQRELSVQVELLRQEVKEKEADFVAREAQLLEELEASRITEQQLRASLWTQEAKTTQLQLQLRSTESQLEVLAAEQQPENQAQAQLASLYSVLQQALGSACESRPELRGGGDSAPSLWGPEPDQNGARRPFKRGSLLTALSAEAVALALQKLHQDLWKAQQARDDLRDQIQKLKQHLTDTEAQKSQVHSDLQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETVASLQSRLRQAELQKMEAQNEQELLQASKEKLTAQVERLQAFVAEAHAQASAASVLEEDLRTARSALKLKNEEVESERERAQALQEQSELKVAQGKALQENLALLAQTLSNREREVETLQTEIQELEKQREMQKAALELLSLDLKQRSQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQQLSVQQDQIRELEKDRETQRSVLEHQLLELEKKAQVIESQRGQIQDLKKQLVTLECLALELEESHHKVEGQQQVIAELESQREMQRVALTHLTLDLEERSQDLQAQSSQLHELESHGTHLARELQERDQEVKAQRQQIEELQKQKEQLTQDLERKGQELMLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQEMASQRQLMLERADNGQSPGKAQRGSLEHLKLILREKEKEVECQHERIQELEEHVGQVEQQLQGLHRKMGETSLLLTHREQEVATLQRHLQEAKDQGELKEQALQGQLEEAQRALAQRDQELEALQQEQQQTLAQEESMKQKTGALQAALEQAQVTLKERQGELEEHRERAQRLQEELVLEGRQVRALEEVLADLRSEIREHEKAVLALQQQCAEQAQEHEAEARTLQDSWLRAQATLSEQEQELAALRAENQYSRHQEEAAWGQAEALQEALSKAQAALQDKEQSLLEQAELSCTLEASTTALQASLDNCQSRARQLEEALKIREGEIQAQGLQHQEVTQQLQQALSQKEEKLRQQEEQRQLLEKALTQSSQENGIQEKQSLEQERKEDTGGLVASLRELQRTLAQKEEEILMLREAQQRQSLEASSPSHRAFPAEKPAPQLCQELERLQNALRQTEAREIEWREKAQDLARSLAQSKASNNSLQEIAMLLQASVLERESEQQRLQEELVLSRQALEEQQSHGSHSTSRADRGPKAGQDVHPGKVVVAEPSPGVEEKEQWTQRLERLQQAVAQLEFDRSKLQHHNAQLRITLELVERERRKLKRDSMRASRAGSLEMKEAMASSPAQQDGRAAQRGSSDSMRVVELQREVALLRAQLALERKQRQDYIARSVQTSRELAGLHHSLSHSLLTVAQAPEATVLEAETRKLDESLSQSLASPEPVLLHPSLDTAQTTPR", "length": 2123, "header": "tr|A0A9J7GZY7-1|A0A9J7GZY7_CRIGR Computationally mapped isoform of Centrosome-associated protein CEP250 isoform X5 OS=Cricetulus griseus OX=10029 GN=Cep250 PE=4 SV=1 CANONICAL=A0A8C2LVR8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H174-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR8/entry#A0A9J7H174-1", "sequence": { "sequence": "METGSPGLNMKPKSLQLVLEEQVLALQHQMAENQAASWQKLKNSQEAQKRQATLVRKLQAKVLQYRSWCQELEKRLEATGCRCESLVEVNTELRLHMEKADVVNKALREDVEKLTVDWSRARDELIRKESQWRLEQEFFKGYLKGEHDRLLNLWREVVTFRRHFLKMKSATDRDLTELKAEHAKLSGSLLTCCLRLTVRAQSRESSGSGRTENEPAQLLLLVAKTQALEKEAHEKSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMVKALRETMETLETNHAELMEHEVSLSRNAQEEMLSLQHVIKDIAQVLASVEEEDTVTHSSDHESSLQLDCSGFSPFDPQNPDKALTLVRSVLTRRQQAVQDLRQQLSGCQEAMSFLQQQHRQWEEEGEALRERLHKLTGERDALAGQTVDLQGEVDSLSKERELLQKARGELQEQLEVLEQEAWRLRRVNMELQLQGDSAQGEKQEQQEELHMAVRERELLQEMLVSLEAKQSESLSELMTLREALESSRLEGELLRQEQVEVTAAWARAEQSIAELSASENSLKAEVADLRAAAVKLGALNEALALDKVGLNQQLLQLEQENQSVCSRAEAAEHLRSALQVDLAEAERHREALWEKNTQLQTQLQKAEESGAELQAELKSIREEKEELKEKLSEAHHQQEAATAQLEQLHQDTERQQETLARAVQEKETLVRERATLEVRLQAVERDRQDLTEQVLGLRSAKEQLESNLFETQQQNSVIEVTKGQLEIQVQTITQAKEVIQGEVKCLKLELDAERSRAEQERDAVARQLAQAEQEGQAALEQQKVAHEEELNRLQEKWEKERSLLQQELEKALETLERERTELEVRLREQQTETEALRAQREEERTHADSTLYQMQLETEKERVSLLETLLQTQKELADATQQLERLRKDMKIQKLQEQETTDMLQTQLQGAQQELKEATQQHSEEHAAFRKDREDLQKQVEDLKSQLVTQDDSHRLVKQEIQEKMKEVQEYSRIQKELEKEKASLALSLVEKEGRLLILQEADSVRQQELNSLRQDIQEAQEGQRELSVQVELLRQEVKEKEADFVAREAQLLEELEASRITEQQLRASLWTQEAKTTQLQLQLRSTESQLEVLAAEQQPENQAQAQLASLYSVLQQALGSACESRPELRGGGDSAPSLWGPEPDQNGARRPFKRGSLLTALSAEAVALALQKLHQDLWKAQQARDDLRDQIQKLKQHLTDTEAQKSQVHSDLQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETVASLQSRLRQAELQKMEAQNEQELLQASKEKLTAQVERLQAFVAEAHAQASAASVLEEDLRTARSALKLKNEEVESERERAQALQEQSELKVAQGKALQENLALLAQTLSNREREVETLQTEIQELEKQREMQKAALELLSLDLKQRSQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQQLSVQQDQIRELEKDRETQRSVLEHQLLELEKKAQVIESQRGQIQDLKKQLVTLECLALELEESHHKVEGQQQVIAELESQREMQRVALTHLTLDLEERSQDLQAQSSQLHELESHGTHLARELQERDQEVKAQRQQIEELQKQKEQLTQDLERKGQELMLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQEMASQRQLMLERADNGQSPGKAQRGSLEHLKLILREKEKEVECQHERIQELEEHVGQVEQQLQGLHRKMGETSLLLTHREQEVATLQRHLQEAKDQGELKEQALQGQLEEAQRALAQRDQELEALQQEQQQTLAQEESMKQKTGALQAALEQAQVTLKERQGELEEHRERAQRLQEELVLEGRQVRALEEVLADLRSEIREHEKAVLALQQQCAEQAQEHEAEARTLQDSWLRAQATLSEQEQELAALRAENQYSRHQEEAAWGQAEALQEALSKAQAALQDKEQSLLEQAELSCTLEASTTALQASLDNCQSRARQLEEALKIREGEIQAQGLQHQEVTQQLQQALSQKEEKLRQQEEQRQLLEKALTQSSQENGIQEKQSLEQERKEDTGGLVASLRELQRTLAQKEEEILMLREAQQRQSLEASSPSHRAFPAEKPAPQLCQELERLQNALRQTEAREIEWREKAQDLARSLAQSKASNNSLQEIAMLLQASVLERESEQQRLQEELVLSRQALEEQQSHGSHSTSRADRGPKAGQDVHPGKVVVAEPSPGVEEKEQWTQRLERLQQAVAQLEFDRSKLQHHNAQLRITLELVERERRKLKRDSMRASRAGSLEMKEAMASSPAQQDGRAAQRGSSDSMRVVELQREVALLRAQLALERKQRQDYIARSVQTSRELAGLHHSLSHSLLTVAQAPEATVLEAETRKLDESLSQSLASPEPVLLHPSLDTAQTTPR", "length": 2399, "header": "tr|A0A9J7H174-1|A0A9J7H174_CRIGR Computationally mapped isoform of Centrosome-associated protein CEP250 isoform X4 OS=Cricetulus griseus OX=10029 GN=Cep250 PE=4 SV=1 CANONICAL=A0A8C2LVR8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H1Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR8/entry#A0A9J7H1Z7-1", "sequence": { "sequence": "METGSPGLNMKPKSLQLVLEEQVLALQHQMAENQAASWQKLKNSQEAQKRQATLVRKLQAKVLQYRSWCQELEKRLEATGGLIPQRWEGVEEPNLEQLLVRLEEEQQRCESLVEVNTELRLHMEKADVVNKALREDVEKLTVDWSRARDELIRKESQWRLEQEFFKGYLKGEHDRLLNLWREVVTFRRHFLKMKSATDRDLTELKAEHAKLSGSLLTCCLRLTVRAQSRESSGSGRTENEPAQLLLLVAKTQALEKEAHEKSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMVKALRETMETLETNHAELMEHEVSLSRNAQEEMLSLQHVIKDIAQVLASVEEEDTVTHSSDHESSLQLDCSGFSPFDPQNPDKALTLVRSVLTRRQQAVQDLRQQLSGCQEAMSFLQQQHRQWEEEGEALRERLHKLTGERDALAGQTVDLQGEVDSLSKERELLQKARGELQEQLEVLEQEAWRLRRVNMELQLQGDSAQGEKQEQQEELHMAVRERELLQEMLVSLEAKQSESLSELMTLREALESSRLEGELLRQEQVEAEQSIAELSASENSLKAEVADLRAAAVKLGALNEALALDKVGLNQQLLQLEQENQSVCSRAEAAEHLRSALQVDLAEAERHREALWEKNTQLQTQLQKAEESGAELQAELKSIREEKEELKEKLSEAHHQQEAATAQLEQLHQDTERQQETLARAVQEKETLVRERATLEVRLQAVERDRQDLTEQVLGLRSAKEQLESNLFETQQQNSVIEVTKGQLEIQVQTITQAKEVIQGEVKCLKLELDAERSRAEQERDAVARQLAQAEQEGQAALEQQKVAHEEELNRLQEKWEKERSLLQQELEKALETLERERTELEVRLREQQTETEALRAQREEERTHADSTLYQMQLETEKERVSLLETLLQTQKELADATQQLERLRKDMKIQKLQEQETTDMLQTQLQGAQQELKEATQQHSEEHAAFRKDREDLQKQVEDLKSQLVTQDDSHRLVKQEIQEKMKEVQEYSRIQKELEKEKASLALSLVEKEGRLLILQEADSVRQQELNSLRQDIQEAQEGQRELSVQVELLRQEVKEKEADFVAREAQLLEELEASRITEQQLRASLWTQEAKTTQLQLQLRSTESQLEVLAAEQQPENQAQAQLASLYSVLQQALGSACESRPELRGGGDSAPSLWGPEPDQNGARRPFKRGSLLTALSAEAVALALQKLHQDLWKAQQARDDLRDQIQKLKQHLTDTEAQKSQVHSDLQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETVASLQSRLRQAELQKMEAQNEQELLQASKEKLTAQVERLQAFVAEAHAQASAASVLEEDLRTARSALKLKNEEVESERERAQALQEQSELKVAQGKALQENLALLAQTLSNREREVETLQTEIQELEKQREMQKAALELLSLDLKQRSQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQQLSVQQDQIRELEKDRETQRSVLEHQLLELEKKAQVIESQRGQIQDLKKQLVTLECLALELEESHHKVEGQQQVIAELESQREMQRVALTHLTLDLEERSQDLQAQSSQLHELESHGTHLARELQERDQEVKAQRQQIEELQKQKEQLTQDLERKGQELMLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQEMASQRQLMLERADNGQSPGKAQRGSLEHLKLILREKEKEVECQHERIQELEEHVGQVEQQLQGLHRKMGETSLLLTHREQEVATLQRHLQEAKDQGELKEQALQGQLEEAQRALAQRDQELEALQQEQQQTLAQEESMKQKTGALQAALEQAQVTLKERQGELEEHRERAQRLQEELVLEGRQVRALEEVLADLRSEIREHEKAVLALQQQCAEQAQEHEAEARTLQDSWLRAQATLSEQEQELAALRAENQYSRHQEEAAWGQAEALQEALSKAQAALQDKEQSLLEQAELSCTLEASTTALQASLDNCQSRARQLEEALKIREGEIQAQGLQHQEVTQQLQQALSQKEEKLRQQEEQRQLLEKALTQSSQENGIQEKQSLEQERKEDTGGLVASLRELQRTLAQKEEEILMLREAQQRQSLEASSPSHRAFPAEKPAPQLCQELERLQNALRQTEAREIEWREKAQDLARSLAQSKASNNSLQEIAMLLQASVLERESEQQRLQEELVLSRQALEEQQSHGSHSTSRADRGPKAGQDVHPGKVVVAEPSPGVEEKEQWTQRLERLQQAVAQLEFDRSKLQHHNAQLRITLELVERERRKLKRDSMRASRAGSLEMKEAMASSPAQQDGRAAQRGSSDSMRVVELQREVALLRAQLALERKQRQDYIARSVQTSRELAGLHHSLSHSLLTVAQAPEATVLEAETRKLDESLSQSLASPEPVLLHPSLDTAQTTPR", "length": 2418, "header": "tr|A0A9J7H1Z7-1|A0A9J7H1Z7_CRIGR Computationally mapped isoform of Centrosome-associated protein CEP250 isoform X3 OS=Cricetulus griseus OX=10029 GN=Cep250 PE=4 SV=1 CANONICAL=A0A8C2LVR8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JTI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR8/entry#A0A9J7JTI4-1", "sequence": { "sequence": "MELQLQGDSAQGEKQEQQEELHMAVRERELLQEMLVSLEAKQSESLSELMTLREALESSRLEGELLRQEQVEVTAAWARAEQSIAELSASENSLKAEVADLRAAAVKLGALNEALALDKVGLNQQLLQLEQENQSVCSRAEAAEHLRSALQVDLAEAERHREALWEKNTQLQTQLQKAEESGAELQAELKSIREEKEELKEKLSEAHHQQEAATAQLEQLHQDTERQQETLARAVQEKETLVRERATLEVRLQAVERDRQDLTEQVLGLRSAKEQLESNLFETQQQNSVIEVTKGQLEIQVQTITQAKEVIQGEVKCLKLELDAERSRAEQERDAVARQLAQAEQEGQAALEQQKVAHEEELNRLQEKWEKERSLLQQELEKALETLERERTELEVRLREQQTETEALRAQREEERTHADSTLYQMQLETEKERVSLLETLLQTQKELADATQQLERLRKDMKIQKLQEQETTDMLQTQLQGAQQELKEATQQHSEEHAAFRKDREDLQKQVEDLKSQLVTQDDSHRLVKQEIQEKMKEVQEYSRIQKELEKEKASLALSLVEKEGRLLILQEADSVRQQELNSLRQDIQEAQEGQRELSVQVELLRQEVKEKEADFVAREAQLLEELEASRITEQQLRASLWTQEAKTTQLQLQLRSTESQLEVLAAEQQPENQAQAQLASLYSVLQQALGSACESRPELRGGGDSAPSLWGPEPDQNGARRPFKRGSLLTALSAEAVALALQKLHQDLWKAQQARDDLRDQIQKLKQHLTDTEAQKSQVHSDLQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETVASLQSRLRQAELQKMEAQNEQELLQASKEKLTAQVERLQAFVAEAHAQASAASVLEEDLRTARSALKLKNEEVESERERAQALQEQSELKVAQGKALQENLALLAQTLSNREREVETLQTEIQELEKQREMQKAALELLSLDLKQRSQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQQLSVQQDQIRELEKDRETQRSVLEHQLLELEKKAQVIESQRGQIQDLKKQLVTLECLALELEESHHKVEGQQQVIAELESQREMQRVALTHLTLDLEERSQDLQAQSSQLHELESHGTHLARELQERDQEVKAQRQQIEELQKQKEQLTQDLERKGQELMLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQEMASQRQLMLERADNGQSPGKAQRGSLEHLKLILREKEKEVECQHERIQELEEHVGQVEQQLQGLHRKMGETSLLLTHREQEVATLQRHLQEAKDQGELKEQALQGQLEEAQRALAQRDQELEALQQEQQQTLAQEESMKQKTGALQAALEQAQVTLKERQGELEEHRERAQRLQEELVLEGRQVRALEEVLADLRSEIREHEKAVLALQQQCAEQAQEHEAEARTLQDSWLRAQATLSEQEQELAALRAENQYSRHQEEAAWGQAEALQEALSKAQAALQDKEQSLLEQAELSCTLEASTTALQASLDNCQSRARQLEEALKIREGEIQAQGLQHQEVTQQLQQALSQKEEKLRQQEEQRQLLEKALTQSSQENGIQEKQSLEQERKEDTGGLVASLRELQRTLAQKEEEILMLREAQQRQSLEASSPSHRAFPAEKPAPQLCQELERLQNALRQTEAREIEWREKAQDLARSLAQSKASNNSLQEIAMLLQASVLERESEQQRLQEELVLSRQALEEQQSHGSHSTSRADRGPKAGQDVHPGKVVVAEPSPGVEEKEQWTQRLERLQQAVAQLEFDRSKLQHHNAQLRITLELVERERRKLKRDSMRASRAGSLEMKEAMASSPAQQDGRAAQRGSSDSMRVVELQREVALLRAQLALERKQRQDYIARSVQTSRELAGLHHSLSHSLLTVAQAPEATVLEAETRKLDESLSQSLASPEPVLLHPSLDTAQTTPR", "length": 1932, "header": "tr|A0A9J7JTI4-1|A0A9J7JTI4_CRIGR Computationally mapped isoform of Centrosome-associated protein CEP250 isoform X6 OS=Cricetulus griseus OX=10029 GN=Cep250 PE=4 SV=1 CANONICAL=A0A8C2LVR8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JUX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR8/entry#A0A9J7JUX2-1", "sequence": { "sequence": "METGSPGLNMKPKSLQLVLEEQVLALQHQMAENQAASWQKLKNSQEAQKRQATLVRKLQAKVLQYRSWCQELEKRLEATGGLIPQRWEGVEEPNLEQLLVRLEEEQQRCESLVEVNTELRLHMEKADVVNKALREDVEKLTVDWSRARDELIRKESQWRLEQEFFKGYLKGEHDRLLNLWREVVTFRRHFLKMKSATDRDLTELKAEHAKLSGSLLTCCLRLTVRAQSRESSGSGRTENEPAQLLLLVAKTQALEKEAHEKSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMVKALRETMETLETNHAELMEHEVSLSRNAQEEMLSLQHVIKDIAQASVEEEDTVTHSSDHESSLQLDCSGFSPFDPQNPDKALTLVRSVLTRRQQAVQDLRQQLSGCQEAMSFLQQQHRQWEEEGEALRERLHKLTGERDALAGQTVDLQGEVDSLSKERELLQKARGELQEQLEVLEQEAWRLRRVNMELQLQGDSAQGEKQEQQEELHMAVRERELLQEMLVSLEAKQSESLSELMTLREALESSRLEGELLRQEQVEVTAAWARAEQSIAELSASENSLKAEVADLRAAAVKLGALNEALALDKVGLNQQLLQLEQENQSVCSRAEAAEHLRSALQVDLAEAERHREALWEKNTQLQTQLQKAEESGAELQAELKSIREEKEELKEKLSEAHHQQEAATAQLEQLHQDTERQQETLARAVQEKETLVRERATLEVRLQAVERDRQDLTEQVLGLRSAKEQLESNLFETQQQNSVIEVTKGQLEIQVQTITQAKEVIQGEVKCLKLELDAERSRAEQERDAVARQLAQAEQEGQAALEQQKVAHEEELNRLQEKWEKERSLLQQELEKALETLERERTELEVRLREQQTETEALRAQREEERTHADSTLYQMQLETEKERVSLLETLLQTQKELADATQQLERLRKDMKIQKLQEQETTDMLQTQLQGAQQELKEATQQHSEEHAAFRKDREDLQKQVEDLKSQLVTQDDSHRLVKQEIQEKMKEVQEYSRIQKELEKEKASLALSLVEKEGRLLILQEADSVRQQELNSLRQDIQEAQEGQRELSVQVELLRQEVKEKEADFVAREAQLLEELEASRITEQQLRASLWTQEAKTTQLQLQLRSTESQLEVLAAEQQPENQAQAQLASLYSVLQQALGSACESRPELRGGGDSAPSLWGPEPDQNGARRPFKRGSLLTALSAEAVALALQKLHQDLWKAQQARDDLRDQIQKLKQHLTDTEAQKSQVHSDLQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETVASLQSRLRQAELQKMEAQNEQELLQASKEKLTAQVERLQAFVAEAHAQASAASVLEEDLRTARSALKLKNEEVESERERAQALQEQSELKVAQGKALQENLALLAQTLSNREREVETLQTEIQELEKQREMQKAALELLSLDLKQRSQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQQLSVQQDQIRELEKDRETQRSVLEHQLLELEKKAQVIESQRGQIQDLKKQLVTLECLALELEESHHKVEGQQQVIAELESQREMQRVALTHLTLDLEERSQDLQAQSSQLHELESHGTHLARELQERDQEVKAQRQQIEELQKQKEQLTQDLERKGQELMLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQEMASQRQLMLERADNGQSPGKAQRGSLEHLKLILREKEKEVECQHERIQELEEHVGQVEQQLQGLHRKMGETSLLLTHREQEVATLQRHLQEAKDQGELKEQALQGQLEEAQRALAQRDQELEALQQEQQQTLAQEESMKQKTGALQAALEQAQVTLKERQGELEEHRERAQRLQEELVLEGRQVRALEEVLADLRSEIREHEKAVLALQQQCAEQAQEHEAEARTLQDSWLRAQATLSEQEQELAALRAENQYSRHQEEAAWGQAEALQEALSKAQAALQDKEQSLLEQAELSCTLEASTTALQASLDNCQSRARQLEEALKIREGEIQAQGLQHQEVTQQLQQALSQKEEKLRQQEEQRQLLEKALTQSSQENGIQEKQSLEQERKEDTGGLVASLRELQRTLAQKEEEILMLREAQQRQSLEASSPSHRAFPAEKPAPQLCQELERLQNALRQTEAREIEWREKAQDLARSLAQSKASNNSLQEIAMLLQASVLERESEQQRLQEELVLSRQALEEQQSHGSHSTSRADRGPKAGQDVHPGKVVVAEPSPGVEEKEQWTQRLERLQQAVAQLEFDRSKLQHHNAQLRITLELVERERRKLKRDSMRASRAGSLEMKEAMASSPAQQDGRAAQRGSSDSMRVVELQREVALLRAQLALERKQRQDYIARSVQTSRELAGLHHSLSHSLLTVAQAPEATVLEAETRKLDESLSQSLASPEPVLLHPSLDTAQTTPR", "length": 2423, "header": "tr|A0A9J7JUX2-1|A0A9J7JUX2_CRIGR Computationally mapped isoform of Centrosome-associated protein CEP250 isoform X2 OS=Cricetulus griseus OX=10029 GN=Cep250 PE=4 SV=1 CANONICAL=A0A8C2LVR8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LVR8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LVR8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVR8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762321", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762321", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZC94-1", "protein_name": "Centrosomal protein 250", "gene_name": "CEP250", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAREAARGQACLRRRLHGAEEAQQQQAVLVRKLQEKLLQYRSWCRELEQRLEAGGVSVQGSLSYRWETTEDHSLEKALLQLEEEQQRCENLAEVNTLLREHLDKANEVNLALKEDVGKLTADWMRAREELELKESEWRSEREFYDSYLRGEHNRLLSLWRQVLTFRRHFLEMKTATDRDLSELKAEQMRLSGSILVSCFRLNSGVQLWESVTLGRPVLKDQAQQQVEREINQEALEVMCLQVDEDLEKKELQDRVMELSALLVQSQKQNEEKEKTVKTLNDTVEMLEASRLEVEYEASLTKNAKEENLALQKLIKEITEVVLDDSDSTVGIVQRPESSNVLSCLSSLDAEHAFVLVQETLARRQKAIQALKEELSTRQDSISFLQHQHRQQEEKCKKLQQRLEQLEEENKMSNSHQQHLKSLVLALKCDCENLEKIRGELQQKLELSEQEASRLRQSNTELQLKEDSAQGEKVEQQLAMERAHHDHELVLKDLAALEEKHSLLQNELVAAREKLEESHLQRDLLKQEKHELTVALEKAEKSVAALTGAQNKLNSEIADLHTAAAKMSSINEALALDKVELNKLVLQLEQENELLSDKVNEMERAKVSEQEKITLYKRTNEELCAEKSHLEKLLKKAEEQQEELQMQLRILAEEKEETLEKLNQVYRQQESASSGLEQLRQQSSRQEDAVAKVSKEKEFLVHEKAALEVRLAAVERDRQGLSEQLAEARSVKDTLESSLFEAQQQLSHLEITKSQLEIQLHTVIQAKEVIQGEVKCLQYELETERCLMKQEQENMAQRLIQIEEQHNNTLKLQQTDHEVEINKLLQDLASEREGRQLELQEMLELWEKEKAEAEGQHEKKLFDMKEKVATMQAQQEEERTRVESANQEILTEKENEKKALLETLLQTQGELTEACHQLEQLRQEVKEQQEYEQNITEKLQAELQETHCKIKMVENMHKEEMENIKEEKNILLQQRDDLQKQVEELTSQLAASEESHQAIGHKAQQELSEAQELSRQKVLEVVHLQKILEEERGQWEEVEHQNKELQVCLQSLEGERSRWEEVERHNTEFQASLKALESERERLSLSLEQKELSLKTLEENNLVQQNEVSKLHSAIQQAQQLHSDHRREIQELNNQVQTLQEVVLEKEASLAAREKQLLQDLEESRAGERCLRDSLHVLEAEMAELHLRLCSTENRAKALATECQQANNAHCEAQSQLDKLHLVLHHVLCDSTDKSSDLVAWSSEQDHVWGLTVSQAKDLHVELTVDRVAAALQDLRQDLKQTQQDLNDAGKKVQDLELELSKRQAERDHFSAHNQELQKQLAQSQEETQMVEGKKNSLQAALQAEAAALKKEAITLHQEVASLERKLESAEKQKKDVLHERDRLQAVEEKLMWEIKILQESVTASETRANTAADMNHSLEQELQTTLSVLKTKNKEVDAQWEKIQMLQKEAADVKALQENLIQVNAILSKREGEMKLYQEQMRMLENQKEMHKTTLDQVIKDIKEKKEKTESQQEQIQELEKQQELQRTAISKMSKDLEDRDKEIRSQQEEIWELEKQQELQRTVVSKMTKDLAHRDQEIQSQQEEIQELEKERELQRTAASKMSKDLKERDEKIRSQQELIEELEKQQELQRTALSKMSKNLEERDQEIKSQQELIEELKKQQELQRTVVSRMSKNLEDRDQEIKSLQELIQELEKQREIQRTAVSKMNKDLEERDQEIRSQQEEIQELEKQRELQRTILSKMSKDLEEKDQVIKFQEGKVMILEQHGTSQVRSLLVDLDHMKGNLKEKNLELMSLNQQIKELEMEREEVKSLHTSLEQLRAVLRDRENESDSQRDQLRLFQQYKEHQEEYLQELQDKVEKMTLSLSKKDQELESQQKQIQEAEEVMEKKLKTVCDQLEQTLETLKEKERLLDIQKQQTREYEEKTEQMNVLCRDLEYTKAILREKDLMIESQKELIETFQKQEDDSMQQKEILQHLKGALKEQEQETLSLRKQCEAFKEKEEKHKTDQVILQETKITLKERERKIEVLEKAVSKLQQQNDDTMMQTTAIVQKLQCAESSLAARDQEIASLKEHVQELQKQKESEAKQVKSLQQDLNKMSKTMKKNNLQILKQSEQINVFHICEESRKVALTSCQNQVSLLEEVVRKRDEDNETLVQKLQHQEEELKTLQNLQLMLSEKKEEIKRHREEEKFPEEALHGSEWETKAQGEQKKSEDEEIRGLHEDLQYVQQTLTKKDEEIKYQRDRVKYLEKTLAGKEKELRRQSELLKQLTSALHWKDEGETLKKQIQKLQKWEEEEAENRRVLQERDQFLQRQKELAQQLEDERKVKGEELKRVIAILKQTESGEIEWKEKAQALTLALSKSEMTNGTLREEIAILQSMVSERDKDRFHLQEAFEGGENLSWLLEKKLLWQRLECLQQAVARLEHEKSELKQLNVELKITLEQVEHERRRLKRSCRRQSQPNANRFSLSESDEDKMPASRKEEARALCSQLAELQNQVTLLQQQLAQERKYKQDYIECCAKTSQELLDLHQELSYSLEAVIREPKAAVLEAETQKLDLSLNHTLALISLDCRSPERQLLHSAVRSTTRDGLR", "length": 2594 }, "evidence": [ { "id": "A0A8C2LVR8", "url": "https://omabrowser.org/oma/group/A0A8C2LVR8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AAA9S885-1", "protein_name": "Centrosomal protein 250", "gene_name": "CEP250", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "METGGPGLNNMKPRSLQLVLEEQVLALQQQMAENQAASWRKLKSSQEAQQRQAALVRKLQAKVLQYRSWCQELEKRLEATGCRCENLVEVNTQLRLHMEKADVVNKALREDVEKLTVDWSRARDELMRKESQWQMEQEFFKGYLKGEHGRLLGLWREVVTFRRHFLEMKSATDRDLTELKAEHARLSGSLLTSCLRLTVGVPPSRESDGSGRLNGNEPSQLMLLLAKTQELEREAHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMVKALRATMEILEANHAELMEHEASLSRNAQEEKLSLQQVIQDITQAMVEEEDSMAQGSSHESSLQLDPGGFSSRFDSQQPDKAVSLVRSVLTQRRQAVQDLRQQLSGCQEAVSSWQQQHHQWEEEGEALRQRLQQLTGERDTLAGQTVDLQGEVDSLSRERELLQKTREELQQQLEVLEQEAWRLRRTNMELQLQGDSAQGEKEEQQEELHLAVRERERLQETLVVLEARQSESLSELICLREALESSRLEGELLRQEQTEVTAALARAEQSIVELSSAENSLKAEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEQEKQSVCRRMEAAEQARSTLQVDLAEAERSREALWEKNSHLEAQLQKTEETRAELQADLRGIQEEKEEIQEKLSETYHQQEAASAQIEQLKQETTRQEEMLAREVQEKEALAREKAALEVRLQAVERDRQELAEQLLGLSSAKEVLESSLFEAQQQNSLTEVTKGQLEVQIQTVTQAKEVIQGEVKCLQLELDTERSRAEQARDTAARQLAQAEQEGQAALQQLKSAHEEEVNRLQEKWEEERSRHRQELEKVLESLEREKMELEARLREQQAEMEAMRAQREEERAEAESALCQMQLETEKERMSLLETLLQTQKELAEASQQLERLRQDMKVQQLKEQETTGMLQTQLQEAQQALEQAAQQHRDSLATLQQEGRVLLQDKTDLQKQVEDLKSQLLSKEASQRFVDQEVQEKLREAQECSRIQKELEREKASLTLSLVEKEQRLLVLQEADSVQQQELSSLRQDMQEAQAGQKELSTQVELLKQEVKEKEADFLAQETQLLEELEASRVTEQQLRASLWAQETKVAQLQLRLRSTESRLEALVAEQQPGHQAQVQLASLYSVLQQALGSACESRLELNGGGDSAPSLWGPEPDQNGARILFKRGPLLTALSVEAVAAALHKLHQDLWKTQQARDDLRDQAQKLEQRLSDMEAEKSQVHTELQALQRQLSQNEEEKSKWEGKQNSLESELMELRETVASLQSRLQQAELQGVEAQNERKLLQAAKESLTAQVEHLQASITEARAQASAAVALEEDLRMARSALKLKNEEVASERQRAQALQEQGELKVAQGKALQENLARLAQALSEREGEVETLQGKIEELEKQREMQKAVLEVLSLDLKKRNREVDLQQGQIQELEECRSVLEHLPVAVQEREQQLALQRERIRELEKDRETQTSILEHHLLELEKKVQVIESQKGQIQDLKKQLVTTECLALELEEKRHKTESQQKAIEELEGQREAQRVALTHLTLDLEERSQELLAQGNRIQELEGHSTLLASELQEKEQEAMAQQDQIRDLQRQKERLSQDLERREQELVLLKERTQSLEDQRSRQTKILEEDLEQIKLALRERGRELVSQRQLRQEWAEEGKGQSKAQRGSLEHMKLILRDKEKEVECQQEHIQELREHRDQLEQELQGLHRKVSETSLLLTQREQEIAVLQQHLQEAQDQGELKEQELQGQLEETQRVLVQRTQELQALQQQEAQDQEKNVKEQADSLQTALEQAHAALEERRAELEEHKEHARRLQEELAVEGRRSQALEEVLGDLRAEAREQEKVLRALQQQCADQAQEHEAEARGLRDSWLQAEALLDARDRELEALRAEGQASQRQEEAARGQAEALQKALGQAQAALREKEQHLHGQAELSRNLEASTATLQAALDSCQAQARQLEETLRKREGEIQDGDLRHQETVQQLQQALAQRDKELRELRRQGQLLEKSLAQEKQERRHEREGEEVRGLRESLRELQRTLAQKEDELLELREAQQRKDLEDAPHSHKTSPREEPSSPLDSSGPRLQRELERLQRALRQTEAREIEWREKAQHLALSLAQSKASVSSLQEAALLLQASVLERDSEQQRLQDELELTRQALEKERLHSLGLTSQAEQGPGGEPGIRLGEVSEVKMEPSPEAEEKQRWEQRLEHLQRAVAQLEVDRSRLQHHNTQLRTTLEQVERERRKLKRESMRASRAGVLESSGATTPSPTPQDGRGGQKVSSDATHMAELQKEVALLRAQLALERKQKQDYIARSVQTSRELAGLHHSLSHSLLAVAQAPEATVLEAETRKLDESLTQSLTSPGPILLCRSPSPAQGASR", "length": 2408 }, "evidence": [ { "id": "A0A8C2LVR8", "url": "https://omabrowser.org/oma/group/A0A8C2LVR8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1M7J7-1", "protein_name": "Centrosomal protein 250", "gene_name": "Cep250", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METGSPGLNMKPQSLQLVLEEQVLALQQQMAQNQAASWRKLKNSQEAQKRQATLVRKLQAKVLQYRSWCQDLEKRLEATGGLIPQRWESVEEPNLEQLLIRLEEEQQRCESLVEVNTELRLHMEKADVVNKALQEDVEKLTVDWSRARDELMRKESQWRMEQEFFKGYLRGEHGRLLSVWREVVTFRRHFLKMKSATDRDLTELKAEHARLSGSLLTCCLRLTLRAQSRDSSGSGRSDESEPAQLLLLVAKTQALEKEAHEKSQELMQLKSQGDLEKAELQDRVTELSALLTQSQKQNKDYEEMVKALRGTMEILETNHAELMEHEASLSRNAQEEKLSLQHVIKDITQALASVEEEDTVTQTPGSENSLQSDYNDLSQFDSQDPNKALTLVHSVLTRRQQAVQDLRQQLSGCQEAMSFLQQQHNQWEEEGKALRERLQKLTGERDALAGQTVDLQGEVDSLSKERELLQTARGELQQQLEVLEQEAWRLRRVNVELQLQGDSAQGEKLEQQEELHLAVRERERLQETLVGLEAKQSESLSELIALREALESSRLAGELLKQEQEEVAAALARAEQSIVELSSSENSLKAEVADLRAAAVKLGALNEALALDKVALNQQLLQLEQENQSMCSRVEAAEQLRSALQVDLAEAERSREALWEEKTHLETQLRKAEETGAELQAELRGAREEKEELKEKLNEAHHQQEAATAQLQQLHQDAERQEEALARAGQEKEALVRERAALEVRLQAVERDRQDLAEQVLGLRSAKEQLEGNLFEAQQQNSVIQVTKSQLEVQIQTIIQAKEVIQGEVKCLKLELDTERSHAEQERDAVARQLAQAEQEGQAALERQKVAHEEEVNRLQEKWEKERALLQQKLDKTLETLERERTELEMKLREQHTETEALRAQREEERTQADSALYQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGMLQAQLRGAQQELKEAIQQHRDDLAAFQKDKIDLQKQVEDLTSQLVTHNDSQRLVKQEIEEKVREAQECSRIQKELEKEKASLTLSLVEKEKRLLVLQEADSVRQRELVSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRIAERQVRASLWAQEAKAAQLQLQLRSTEAQLEALVAEQQPENQAQAQLRSLYSVLQQALGSACERRPELRGGGDSVPTPWGSDPDQNGASRLLKRGPLLTALSAEAVALALQKLHQDLWKAQQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGKQNSLESELRDLHETMASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVTEARAQASAAGVLEEDLRTARSALKLKNEEIESERERAQALQEQGELKVAQGKALQENLTLLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRTALEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHRKVEGQQKVITELEGQRELQRVALTHLTLDLEERSQELQTQSSQLHELENHSTRLAKELQERDQEVMSQRQQIEELQKQKEQLTQDLERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERGQELASQWQLMQERAEDGKSPSKAQRGSLEHLKLILRDKEKEVECQQERIQELQEHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQRLQEAKEQGELREQVLQGQLEEAQRALAQRDHELEALRQEQQQTRGQEESMKQKTSALQAALEQAHVTLKERQGELEEHRGQVQRLQEELIVEGRQVRALEEVLGDLRAESREHEKTVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLAEQEQELEALRAENQYSRQQEEAAFGQAEALQEALSKAQATLQEKEQRLLEQAELSCTLEASTATLQATLDTCQARARQLEEALRVREGEIQTQALQHQEAMQHLQQELCQKEEDLRQQDEQRQLLEKAVAQRSQENGIQEKQSLEQEKEEETRGLLESLKELQLTVAQKEEEILMLREAQQRQNQEASSPSHRSFPAEKPSLQLLLAQQDLERLQNALRQTEAREIEWREKAQGLALSLAQSKASISSLQEIAMFLQASVLERESEQQRLQEELVLSRQALEEQQSRGPHSSSRADQGPKAGQDTEPGEVIEAEPSPGVGEKEQLRQRLERLQQAVAELEVDRSKLQCHNAQLRTTLEQVERERRKLKRDSLRASRAGSLEARETMNSSPTQQDGRGSQRGSSDSMLMVELQREVALLRAQLALERKQRQDYIARSVQTSRELAGLHHSLSHSLLTVAQAPEATVLEAETKKLDESLNQSLTSPAPFLHPSLDTTQNTHR", "length": 2428 }, "evidence": [ { "id": "A0A8C2LVR8", "url": "https://omabrowser.org/oma/group/A0A8C2LVR8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q60952-1", "protein_name": "Centrosome-associated protein CEP250", "gene_name": "Cep250", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METGSPGLNMKPQSLQLVLEGQVLALQQQMAENQAASWRKLKNSQEAQKRQATLVRKLQAKVLQYRSWCQDLEKRLEATGGLIPQRWESVEEPNLEQLLIRLEEEQQRCESLVEVNTELRLHMEKADVVNKALQEDVEKLTVDWSRARDELVRKESQWRMEQEFFKGYLRGEHGRLLNLWREVVTFRRHFLKMKSATDRDLTELKAEHARLSGSLLTCCLRLTLRAQSRESSGSGRTEESEPARLLLLVAKTQALEKEAHEKSQELMQLKSHGDLEKAELQDRVTELSALLTQSQKQNEDYEKMVKALRETMEILETNHAELMEHEASLSRNAQEEKLSLQQVIKAITQALASVEEEDTVTQSSGHEDSLQSDCNGLSQFDPQDPDRALTLVQSVLTRRQQAVQDLRQQLSGCQEAMSFLQQQHDQWEEEGRALREKLQKLTGERDALAGQTVGLQGEVDSLSRERELLQKARGELQQQLEVLEQEAWRLRRMNMELQLQGDSAQGEKLEQQEELHLAVRERERLQETLVGLEAKQSESLSELLTLREALESSRLEGELLKQERVEVAAALARAEQSIVELSGSENSLKAEVADLRAAAVKLGALNEALALDKVELNQQLLQLEQENQSLCSRVEAAEQLRSALQVDLAEAERRREALWEKKTQLETQLQKAEEAGAELQAELRGTREEKEELKDKLSEAHHQQETATAHLEQLHQDAERQEETLARAVQEKEALVRERAALEVRLQAVERDRQDLTEHVLGLRSAKEQLESNLFEAQQQNSVIQVTKGQLEVQIQTIIQAKEVIQGEVKCLKLELDAERTRAEQEWDAVARQLAQAEQEGQASLERQKVAHEEEVNRLQEKWEKERSWLQQELDKTLETLERERAELETKLREQQTEMEAIRAQREEERSQADSALYQMQLETEKERVSLLETLLRTQKELADASQQLERLRQDMKIQKLKEQETTGMLQAQLQETQQELKEAAQQHRDDLAAFQKDKLDLQKQVEDLMSQLVAHDDSQRLVKEEIEEKVKVAQECSRIQKELEKENASLALSLVEKEKRLLILQEADSVRQQELSSLRQDIQEAQEGQRELGVQVELLRQEVKEKEADFVAREAQLLEELEASRVAEQQLRASLWAQEAKATQLQLQLRSTESQLEALVAEQQPENQAQAQLASLCSVLQQALGSACESRPELRGGGDSAPTLWGPDPDQNGASRLFKRWSLPTALSPEAVALALQKLHQDVWKARQARDDLRDQVQKLVQRLTDTEAQKSQVHSELQDLQRQLSQSQEEKSKWEGRQNSLESELRDLHETAASLQSRLRQAELQKMEAQNDRELLQASKEKLSAQVEHLQACVAEAQAQADAAAVLEEDLRTARSALKLKNEELESERERAQALQEQGELKVAQGKALQENLALLAQTLSNREREVETLQAEVQELEKQREMQKAALELLSLDLKKRSREVDLQQEQIQELEQCRSVLEHLPMAVQEREQKLSVQRDQIRELENDREAQRSVLEHQLLDLEQKAQVIESQRGQIQDLKKQLGTLECLALELEESHHKVESQQKMITELEGQREMQRVALTHLTLDLEERSQELQAQSSQLHELENHSTHLAKELQERDQEVTSQRQQIDELQKQQEQLAQALERKGQELVLQKERIQVLEDQRTLQTKILEEDLEQIKHSLRERSQELASQWQLVHERADDGKSPSKGQRGSLEHLKLILRDKEKEVECQQERIQELQGHMGQLEQQLQGLHRKVGETSLLLTHREQETATLQQHLQEAKEQGELREQVLQGQLEEAQRDLAQRDHELETLRQEKQQTQDQEESMKLKTSALQAALEQAHATLKERQGELEEHREQVRRLQEELEVEGRQVRALEEVLGDLRAESREHEKAVLALQQRCAEQAQEHEAEARTLQDSWLQAQATLTEQEQELAALRAENQYSRRQEEAAVSQAEALQEALSKAQAALQEKEQSLLEQAELSHTLEASTAALQATLDTCQASARQLEEALRIREGEIQAQALQHHEVTQHLQQELCQKKEELRQLLEKAGARRSQENGIQEKQSLEQERQEETRRLLESLKELQLTVAQREEEILMLREASSPRHRALPAEKPALQPLPAQQELERLQTALRQTEAREIEWREKAQDLALSLAQSKASISSLQEITMFLQASVLERESEQQRLQEELVLSRQALEEQQSGGPHSTSRADQGPKVGQGSQSGEVETEPSPGVEEKERLTQRLERLQQAVAELEVDRSKLQCHNAQLRTALEQVERERRKLKRDSVRASRAGSLEARETMTSSPTQQDGRGSQRGSSDSVLVVELQREVALLRAQLALERKQRQDYIARSVQTSRELAGLHHSLSHSLLTVAQAPEATVLEAETRKLDESLNQSLTSPGPCLLHPSLDTTQNTHR", "length": 2414 }, "evidence": [ { "id": "A0A8C2LVR8", "url": "https://omabrowser.org/oma/group/A0A8C2LVR8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BV73-1", "protein_name": "Centrosome-associated protein CEP250", "gene_name": "CEP250", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METRSPGLNNMKPQSLQLVLEEQVLALQQQMAENQAASWRKLKNSQEAQQRQATLVRKLQAKVLQYRSWCQELEKRLEATGGPIPQRWENVEEPNLDELLVRLEEEQQRCESLAEVNTQLRLHMEKADVVNKALREDVEKLTVDWSRARDELMRKESQWQMEQEFFKGYLKGEHGRLLSLWREVVTFRRHFLEMKSATDRDLMELKAEHVRLSGSLLTCCLRLTVGAQSREPNGSGRMDGREPAQLLLLLAKTQELEKEAHERSQELIQLKSQGDLEKAELQDRVTELSALLTQSQKQNEDYEKMIKALRETVEILETNHTELMEHEASLSRNAQEEKLSLQQVIKDITQVMVEEGDNIAQGSGHENSLELDSSIFSQFDYQDADKALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAIQAQREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRDDLAALQEESSSLLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEALAAEQQPGNQAQAQAQLASLYSALQQALGSVCESRPELSGGGDSAPSVWGLEPDQNGARSLFKRGPLLTALSAEAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTKASVSSLQEVAMFLQASVLERDSEQQRLQDELELTRRALEKERLHSPGATSTAELGSRGEQGVQLGEVSGVEAEPSPDGMEKQSWRQRLEHLQQAVARLEIDRSRLQRHNVQLRSTLEQVERERRKLKREAMRAAQAGSLEISKATASSPTQQDGRGQKNSDAKCVAELQKEVVLLQAQLTLERKQKQDYITRSAQTSRELAGLHHSLSHSLLAVAQAPEATVLEAETRRLDESLTQSLTSPGPVLLHPSPSTTQAASR", 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"A0A8C2LVS9-1", "uniprot_ac": "A0A8C2LVS9", "uniprot_id": "A0A8C2LVS9_CRIGR", "mass": { "chemical_mass": 77719.0, "monoisotopic_mass": 77719.0 }, "refseq": { "ac": "XP_027287848", "name": "PWWP domain-containing DNA repair factor 3B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287848" }, "gene_names": [ { "name": "Pwwp3b", "type": "recommended", "evidence": [ { "id": "A0A8C2LVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVS9" } ] }, { "name": "Pwwp3b", "type": "synonym", "evidence": [ { "id": "XP_027287848", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287848" } ] } ], "protein_names": [ { "name": "PWWP domain-containing DNA repair factor 3B", "type": "synonym", "evidence": [ { "id": "XP_027287848", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287848" }, { "id": "A0A8C2LVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVS9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027287848", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287848" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LVS9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVS9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Pwwp3b", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVS9", "locus": {} } ], "crossref": [ { "id": "cd06080", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06080", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100771029", "url": "https://www.ncbi.nlm.nih.gov/gene/100771029", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR035504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040263", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040263", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048795", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048795", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771029", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771029", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LVS9", "url": "https://www.orthodb.org/?gene=A0A8C2LVS9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31333", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31333", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31333:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31333:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF20884", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20884", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20886", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20886", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20887", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20887", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027287848", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027287848", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LVS9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LVS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVS9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGEYVLCNWKEQLWPAKVLCRSEISSSSKRKMAFSLKVQILSLDEKITVDSKDIKVLSKAEVETIVSLLAVESEVRVPPREETAYERALKMALEIIRERSTQSQENMPNEEDTTVASESVPQQQDDSPPPKKYRKLESNLQEDSASILLCSESDDSLSDDKLQVRTAIESIASEMETKSSQNFSWCQTYSSFPDDEDDKKEEKIKIDMSASMSMNLSIKEEAEDIKEEKFVPPSDDLTVPKEEAQEIPLEAPTVSAECSIFPENNMEDPGEGPSNQNPCFYGSQTQSSVESEIGAESALPGCSGEYQVSLSACNPVNSDLLLQRLDLEDLEEEARASGKLLSLNPACAAALDNDDEDDDDEDLPRFILCYETRAFETGMIVWFKYQKYPFWPAVIKSIRRKERKASVLFVEANMSPQKKGVRVSFRRLKKYDCKEKQDLVEKARENYRESIDWCVSLICDYRVRLGCGSFTGSFFEYYAADISYPVRKIIKQDTFRNIFPKLHNEDTGEQMAVTSHAKRISFQKILPDRMKPARDRANKNLVDFIVNAKGTEDHLLGILKGTKKSKWLKSFLNAKSFTPCIETYFEDEDQLDEVVKYLQEIYKQIDQKMLTLIKDDKIKFILEVLLPEAIISSISAVDGLDYEAAEAKYLKGPSLGCRERELYDSKILFEKRRRSLANEAH", "length": 682, "header": "tr|A0A8C2LVS9-1|A0A8C2LVS9_CRIGR Isoform 1 of PWWP domain-containing DNA repair factor 3B OS=Cricetulus griseus OX=10029 GN=Pwwp3b PE=3 SV=1 CANONICAL=A0A8C2LVS9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LVS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVS9/entry#A0A8C2LVS9-1", "sequence": { "sequence": "MDGEYVLCNWKEQLWPAKVLCRSEISSSSKRKMAFSLKVQILSLDEKITVDSKDIKVLSKAEVETIVSLLAVESEVRVPPREETAYERALKMALEIIRERSTQSQENMPNEEDTTVASESVPQQQDDSPPPKKYRKLESNLQEDSASILLCSESDDSLSDDKLQVRTAIESIASEMETKSSQNFSWCQTYSSFPDDEDDKKEEKIKIDMSASMSMNLSIKEEAEDIKEEKFVPPSDDLTVPKEEAQEIPLEAPTVSAECSIFPENNMEDPGEGPSNQNPCFYGSQTQSSVESEIGAESALPGCSGEYQVSLSACNPVNSDLLLQRLDLEDLEEEARASGKLLSLNPACAAALDNDDEDDDDEDLPRFILCYETRAFETGMIVWFKYQKYPFWPAVIKSIRRKERKASVLFVEANMSPQKKGVRVSFRRLKKYDCKEKQDLVEKARENYRESIDWCVSLICDYRVRLGCGSFTGSFFEYYAADISYPVRKIIKQDTFRNIFPKLHNEDTGEQMAVTSHAKRISFQKILPDRMKPARDRANKNLVDFIVNAKGTEDHLLGILKGTKKSKWLKSFLNAKSFTPCIETYFEDEDQLDEVVKYLQEIYKQIDQKMLTLIKDDKIKFILEVLLPEAIISSISAVDGLDYEAAEAKYLKGPSLGCRERELYDSKILFEKRRRSLANEAH", "length": 682, "header": "tr|A0A8C2LVS9-1|A0A8C2LVS9_CRIGR Isoform 1 of PWWP domain-containing DNA repair factor 3B OS=Cricetulus griseus OX=10029 GN=Pwwp3b PE=3 SV=1 CANONICAL=A0A8C2LVS9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LVS9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVS9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LVS9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVS9" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771029", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771029", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular exosome", "id": "GO:0070062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070062", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LVS9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVS9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 414, "end_pos": 416, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVS9" }, { "id": "PF20884", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20884" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MUM1-like PWWP", "eco_id": "ECO_0000259", "start_pos": 376, "end_pos": 455, "start_aa": "Phe", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2LVS9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVS9" }, { "id": "PF20887", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20887" }, { "id": "PF20886", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20886" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PWWP", "eco_id": "ECO_0000259", "start_pos": 5, "end_pos": 98, "start_aa": "Tyr", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 183, "end_pos": 185 }, { "start_pos": 216, "end_pos": 218 }, { "start_pos": 414, "end_pos": 416 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LVX9-1", "uniprot_ac": "A0A8C2LVX9", "uniprot_id": "A0A8C2LVX9_CRIGR", "mass": { "chemical_mass": 70730.0, "monoisotopic_mass": 70730.0 }, "refseq": { "ac": "XP_035305887", "name": "ralBP1-associated Eps domain-containing protein 2 isoform X6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305887" }, "gene_names": [ { "name": "Reps2", "type": "recommended", "evidence": [ { "id": "A0A8C2LVX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVX9" } ] }, { "name": "Reps2", "type": "synonym", "evidence": [ { "id": "XP_035305887", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305887" } ] } ], "protein_names": [ { "name": "RalBP1-associated Eps domain-containing protein 2 isoform X6", "type": "synonym", "evidence": [ { "id": "A0A8C2LVX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVX9/entry#names_and_taxonomy" } ] }, { "name": "ralBP1-associated Eps domain-containing protein 2 isoform X6", "type": "synonym", "evidence": [ { "id": "XP_035305887", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305887" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048604.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035305887", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305887" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LVX9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVX9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Reps2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVX9", "locus": {} } ], "crossref": [ { "id": "cd00052", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00052", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100751880", "url": "https://www.ncbi.nlm.nih.gov/gene/100751880", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100751880", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100751880", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LVX9", "url": "https://www.orthodb.org/?gene=A0A8C2LVX9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11216", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11216", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11216:SF64", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11216:SF64", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12763", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12763", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035305887", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035305887", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LVX9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LVX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVX9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GJI9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GJI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJI9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GKL9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GKL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GKL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GKL9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8S4", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8S4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H8S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H8S4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9L7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9L7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H9L7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H9L7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVAAGGGCGTGPPLLLSDSEQQCYSELFARCAGAASGGPGPGPPEGTRVAPGTATAAAGPVADLFRASQLPPETLHQITELCGAKRVGYFGPTQFYVALKLIAAAQSGLPVRTESIKCELPLPRFGMSKSDGEIRFGNPAELHGKKVQIPYLPTEKNSHKRMDDEDKQQESQSPTMSPLASPPSSPPHYQRVSLSHGYSKLRSSTEQMHPAPYETRQPIGQPEGSSSEGPGAKPLRRQASLIRSFSVERELQDNNSNYPDEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQPEYLQAAFPKSKWECAIFDSYSESMPANQQPCDLNRMEKTSAKDMADFPVPTQDVTTGDDKQALKSTVNEPLPKDVAEDTATSKDCYSLKARPRSRSYSSTSIEETMKRGEDPPTPPPRPQKTHSRASSLDLNKVFQPSVPAANSGLLHAPPALPPRPCPTQSEPVSEADLHPQLNRAPSQAAESSPAKKDAIHAQPPSKPIRRKFRSENQTTENQEPAAAVGGAASAAMVKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIALENQLEQLRPVTVL", "length": 649, "header": "tr|A0A8C2LVX9-1|A0A8C2LVX9_CRIGR Isoform 1 of RalBP1-associated Eps domain-containing protein 2 isoform X6 OS=Cricetulus griseus OX=10029 GN=Reps2 PE=4 SV=1 CANONICAL=A0A8C2LVX9-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LVX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVX9/entry#A0A8C2LVX9-1", "sequence": { "sequence": "MEVAAGGGCGTGPPLLLSDSEQQCYSELFARCAGAASGGPGPGPPEGTRVAPGTATAAAGPVADLFRASQLPPETLHQITELCGAKRVGYFGPTQFYVALKLIAAAQSGLPVRTESIKCELPLPRFGMSKSDGEIRFGNPAELHGKKVQIPYLPTEKNSHKRMDDEDKQQESQSPTMSPLASPPSSPPHYQRVSLSHGYSKLRSSTEQMHPAPYETRQPIGQPEGSSSEGPGAKPLRRQASLIRSFSVERELQDNNSNYPDEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQPEYLQAAFPKSKWECAIFDSYSESMPANQQPCDLNRMEKTSAKDMADFPVPTQDVTTGDDKQALKSTVNEPLPKDVAEDTATSKDCYSLKARPRSRSYSSTSIEETMKRGEDPPTPPPRPQKTHSRASSLDLNKVFQPSVPAANSGLLHAPPALPPRPCPTQSEPVSEADLHPQLNRAPSQAAESSPAKKDAIHAQPPSKPIRRKFRSENQTTENQEPAAAVGGAASAAMVKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIALENQLEQLRPVTVL", "length": 649, "header": "tr|A0A8C2LVX9-1|A0A8C2LVX9_CRIGR Isoform 1 of RalBP1-associated Eps domain-containing protein 2 isoform X6 OS=Cricetulus griseus OX=10029 GN=Reps2 PE=4 SV=1 CANONICAL=A0A8C2LVX9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GJI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVX9/entry#A0A9J7GJI9-1", "sequence": { "sequence": "MEVAAGGGCGTGPPLLLSDSEQQCYSELFARCAGAASGGPGPGPPEGTRVAPGTATAAAGPVADLFRASQLPPETLHQITELCGAKRVGYFGPTQFYVALKLIAAAQSGLPVRTESIKCELPLPRFGMSKSDGEIRFGNPAELHGKKVQIPYLPTEKNSHKRMDDEDKQESQSPTMSPLASPPSSPPHYQRVSLSHGYSKLRSSTEQMHPAPYETRQPIGQPEGSSSEGPGAKPLRRQASLIRSFSVERELQDNNSNYPDEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQPEYLQAAFPKSKWECAIFDSYSESMPANQQPCDLNRMEKTSAKDMADFPVPTQDVTTGDDKQALKSTVNEPLPKDVAEDTAANSGLLHAPPALPPRPCPTQSEPVSEADLHPQLNRAPSQAAESSPAKKDAIHAQPPSKPIRRKFRSENQTTENQEPAAAVGGAASAAMVKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIALENQLEQLRPVTVL", "length": 587, "header": "tr|A0A9J7GJI9-1|A0A9J7GJI9_CRIGR Computationally mapped isoform of RalBP1-associated Eps domain-containing protein 2 isoform X8 OS=Cricetulus griseus OX=10029 GN=Reps2 PE=4 SV=1 CANONICAL=A0A8C2LVX9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GKL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVX9/entry#A0A9J7GKL9-1", "sequence": { "sequence": "MEVAAGGGCGTGPPLLLSDSEQQCYSELFARCAGAASGGPGPGPPEGTRVAPGTATAAAGPVADLFRASQLPPETLHQITELCGAKRVGYFGPTQFYVALKLIAAAQSGLPVRTESIKCELPLPRFGMSKSDGEIRFGNPAELHGKKVQIPYLPTEKNSHKRMDDEDKQESQSPTMSPLASPPSSPPHYQRVSLSHGYSKLRSSTEQMHPAPYETRQPIGQPEGSSSEGPGAKPLRRQASLIRSFSVERELQDNNSNYPDEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQPEYLQAAFPKSKWECAIFDSYSESMPANQQPCDLNRMEKTSAKDMADFPVPTQDVTTGDDKQALKSTVNEPLPKDVAEDTATSKDCYSLKARPRSRSYSSTSIEETMKRGEDPPTPPPRPQKTHSRASSLDLNKVFQPSVPAANSGLLHAPPALPPRPCPTQSEPVSEADLHPQLNRAPSQAAESSPAKKDAIHAQPPSKPIRRKFRSENQTTENQEPAAAVGGAASAAMVKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIALENQLEQLRPVTVL", "length": 648, "header": "tr|A0A9J7GKL9-1|A0A9J7GKL9_CRIGR Computationally mapped isoform of RalBP1-associated Eps domain-containing protein 2 isoform X7 OS=Cricetulus griseus OX=10029 GN=Reps2 PE=4 SV=1 CANONICAL=A0A8C2LVX9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H8S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVX9/entry#A0A9J7H8S4-1", "sequence": { "sequence": "MSKSDGEIRFGNPAELHGKKVQIPYLPTEKNSHKRMDDEDKQESQSPTMSPLASPPSSPPHYQRVSLSHGYSKLRSSTEQMHPAPYETRQPIGQPEGSSSEGPGAKPLRRQASLIRSFSVERELQDNNSNYPDEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQPEYLQAAFPKSKWECAIFDSYSESMPANQQPCDLNRMETSAKDMADFPVPTQDVTTGDDKQALKSTVNEPLPKDVAEDTAANSGLLHAPPALPPRPCPTQSEPVSEADLHPQLNRAPSQAAESSPAKKDAIHAQPPSKPIRRKFRSENQTTENQEPAAAVGGAASAAMVKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIALENQLEQLRPVTVL", "length": 459, "header": "tr|A0A9J7H8S4-1|A0A9J7H8S4_CRIGR Computationally mapped isoform of RalBP1-associated Eps domain-containing protein 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Reps2 PE=4 SV=1 CANONICAL=A0A8C2LVX9-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H9L7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVX9/entry#A0A9J7H9L7-1", "sequence": { "sequence": "MEVAAGGGCGTGPPLLLSDSEQQCYSELFARCAGAASGGPGPGPPEGTRVAPGTATAAAGPVADLFRASQLPPETLHQITELCGAKRVGYFGPTQFYVALKLIAAAQSGLPVRTESIKCELPLPRFGMSKSDGEIRFGNPAELHGKKVQIPYLPTEKNSHKRMDDEDKQQESQSPTMSPLASPPSSPPHYQRVSLSHGYSKLRSSTEQMHPAPYETRQPIGQPEGSSSEGPGAKPLRRQASLIRSFSVERELQDNNSNYPDEPWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNGYPLPEGLPPTLQPEYLQAAFPKSKWECAIFDSYSESMPANQQPCDLNRMEKTSAKDMADFPVPTQDVTTGDDKQAANSGLLHAPPALPPRPCPTQSEPVSEADLHPQLNRAPSQAAESSPAKKDAIHAQPPSKPIRRKFRSENQTTENQEPAAAVGGAASAAMVKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIALENQLEQLRPVTVL", "length": 570, "header": "tr|A0A9J7H9L7-1|A0A9J7H9L7_CRIGR Computationally mapped isoform of RalBP1-associated Eps domain-containing protein 2 isoform X9 OS=Cricetulus griseus OX=10029 GN=Reps2 PE=4 SV=1 CANONICAL=A0A8C2LVX9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 468, "start_aa": "Thr", "end_pos": 468, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr468", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 514, "start_aa": "Thr", "end_pos": 514, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr514", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LVX9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LVX9" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LW12-1", "uniprot_ac": "A0A8C2LW12", "uniprot_id": "A0A8C2LW12_CRIGR", "mass": { "chemical_mass": 56454.0, "monoisotopic_mass": 56454.0 }, "refseq": { "ac": "XP_027249586", "name": "ganglioside-induced differentiation-associated protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249586" }, "gene_names": [ { "name": "Gdap2", "type": "recommended", "evidence": [ { "id": "A0A8C2LW12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LW12" } ] }, { "name": "Gdap2", "type": "synonym", "evidence": [ { "id": "XP_027249586", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249586" } ] } ], "protein_names": [ { "name": "Ganglioside-induced differentiation-associated protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8C2LW12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LW12/entry#names_and_taxonomy" } ] }, { "name": "ganglioside-induced differentiation-associated protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_027249586", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249586" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027249586", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249586" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LW12", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LW12" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Gdap2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LW12", "locus": {} } ], "crossref": [ { "id": "cd00170", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00170", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd02905", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02905", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100771093", "url": "https://www.ncbi.nlm.nih.gov/gene/100771093", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035793", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035793", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100771093", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771093", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IHPTFWT", "url": "https://omabrowser.org/oma/group/IHPTFWT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LW12", "url": "https://www.orthodb.org/?gene=A0A8C2LW12", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11106:SF72", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11106:SF72", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01661", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01661", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13716", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13716", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027249586", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027249586", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LW12", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LW12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LW12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LW12-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F3L3", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3L3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F3L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F3L3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JA70", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JA70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JA70-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JA70-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPLGAPSQFVDVDTLLSWGDSYKDELNSHDSTAETFQEDTIRSPFLYNRDINGKVVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNLAARFIIHTVGPKYKNRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLEIHGETIEKVVFAVSELEEATYQKLLPLYFPRSLREESQSLPYLPADIGNADGEPVVPERQIRISEKPGASEDNQEEDEDDGLGVDLSFIGSHAFARMEGDIDKQRKLILQGQLSEAALQKQHQRNYNRWLCQARSEDLSDIASLKALYQTGVDNCGRTVMVVVGRNIPVTLIDMDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRNLKAVYFVHPTFRSKVSTWFFTTFSVSGLKDKIHHIDSLHQLFSAISPEQIDFPPFVLEYDARENGPYFASYPPSPDL", "length": 498, "header": "tr|A0A8C2LW12-1|A0A8C2LW12_CRIGR Isoform 1 of Ganglioside-induced differentiation-associated protein 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Gdap2 PE=3 SV=1 CANONICAL=A0A8C2LW12-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LW12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LW12/entry#A0A8C2LW12-1", "sequence": { "sequence": "MDPLGAPSQFVDVDTLLSWGDSYKDELNSHDSTAETFQEDTIRSPFLYNRDINGKVVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNLAARFIIHTVGPKYKNRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLEIHGETIEKVVFAVSELEEATYQKLLPLYFPRSLREESQSLPYLPADIGNADGEPVVPERQIRISEKPGASEDNQEEDEDDGLGVDLSFIGSHAFARMEGDIDKQRKLILQGQLSEAALQKQHQRNYNRWLCQARSEDLSDIASLKALYQTGVDNCGRTVMVVVGRNIPVTLIDMDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRNLKAVYFVHPTFRSKVSTWFFTTFSVSGLKDKIHHIDSLHQLFSAISPEQIDFPPFVLEYDARENGPYFASYPPSPDL", "length": 498, "header": "tr|A0A8C2LW12-1|A0A8C2LW12_CRIGR Isoform 1 of Ganglioside-induced differentiation-associated protein 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Gdap2 PE=3 SV=1 CANONICAL=A0A8C2LW12-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F3L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LW12/entry#A0A9J7F3L3-1", "sequence": { "sequence": "MEPRTDVTVDRTRTTGCRTGEAKLTKGFNLAARFIIHTVGPKYKNRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLEIHGETIEKVVFAVSELEEATYQKLLPLYFPRSLREESQSLPYLPADIGNADGEPVVPERQIRISEKPGASEDNQEEDEDDGLGVDLSFIGSHAFARMEGDIDKQRKLILQGQLSEAALQKQHQRNYNRWLCQARSEDLSDIASLKALYQTGVDNCGRTVMVVVGRNIPVTLIDMDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRNLKAVYFVHPTFRSKVSTWFFTTFSVSGLKDKIHHIDSLHQLFSAISPEQIDFPPFVLEYDARENGPYFASYPPSPDL", "length": 408, "header": "tr|A0A9J7F3L3-1|A0A9J7F3L3_CRIGR Computationally mapped isoform of Ganglioside-induced differentiation-associated protein 2 isoform X3 OS=Cricetulus griseus OX=10029 GN=Gdap2 PE=3 SV=1 CANONICAL=A0A8C2LW12-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JA70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LW12/entry#A0A9J7JA70-1", "sequence": { "sequence": "MHNKEMLSNNCLLSDSVLECCRTGEAKLTKGFNLAARFIIHTVGPKYKNRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLEIHGETIEKVVFAVSELEEATYQKLLPLYFPRSLREESQSLPYLPADIGNADGEPVVPERQIRISEKPGASEDNQEEDEDDGLGVDLSFIGSHAFARMEGDIDKQRKLILQGQLSEAALQKQHQRNYNRWLCQARSEDLSDIASLKALYQTGVDNCGRTVMVVVGRNIPVTLIDMDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRNLKAVYFVHPTFRSKVSTWFFTTFSVSGLKDKIHHIDSLHQLFSAISPEQIDFPPFVLEYDARENGPYFASYPPSPDL", "length": 412, "header": "tr|A0A9J7JA70-1|A0A9J7JA70_CRIGR Computationally mapped isoform of Ganglioside-induced differentiation-associated protein 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Gdap2 PE=3 SV=1 CANONICAL=A0A8C2LW12-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LW12", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LW12" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LW12", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LW12" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100771093", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100771093", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZUK7-1", "protein_name": "Ganglioside induced differentiation associated protein 2", "gene_name": "GDAP2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDPLGAPSQFVDIDSLPSWSNVCEATQADSHQNPVEKAQVSVRSPFPYRKDLNTKIVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFMHAGPDLKDELQKLKGCRTGEAKLTKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQAMCSVGFCVINSLKRCYPLEDATHIALRTVRRFLEIHGETLEKVVFAVSELEEATYQKLMPLYFPRSLEEEIQSLPYLPADIGNAEGEPVVPERQIRITEKPGIPDDASDEEGLEADLSFIGSHAFARMEGDVDKQRRLILQGQLSEAALQKQHQRNYNRWLCQARAEDLSDIASLKALYQTGVDNCGRTVMVVVGRNIPVTLIDMEKALLYFIHVMDHIAVKEYVLVYFHTLTNDYNQLDSNFLKKLYDVVDAKYKRNLKALYFVHPTFRSKVSTWFFTTFTVSGLKDKIHYVESLQQLFTAIPPEQIDLPPFVLEYDARENGPYYSSYPPSPDL", "length": 495 }, "evidence": [ { "id": "A0A8C2LW12", "url": "https://omabrowser.org/oma/group/A0A8C2LW12/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q54PT1-1", "protein_name": "Protein GDAP2 homolog", "gene_name": "gdap2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTTTPIFSGKIDYKEIKTWDQTEFDEKNLVNDKDKVPIENFHINGPIQFKIDTEINSRICLWMGDICNLNTDTIVYSNSKTLTESDTISDKIFKYGGSEMMNDIQKNGECRYGESIITSGGNLPSRFVVHTVCPTYNPKYLSAAENALNSCYRSAFHLSMDVKSKSISFSTLHSEKRQFPSVGGCHIALRTIRRFLEKPFSKSFEKVILAINTFEDLRLYEQMLPIYFPRNQQELKFSQISLPKDVGDENGEAIVESRKIRIIETPSTIIREPEDYNCFYSNNNNNNNNVNNVNNNNSNNNNSNNNNSSSNNIDIIQKNNKNEFNNYKYDSIDKILNPFSSNFSSSPYDATMDNDSFMLKREDPDIEKRRQFSKKSEKQIENEKLKAQFQTLLTRSKVEDLSDVSRLNFTLQTTDDQNRPIVVIIGSQLNSRKDLYDQVLLYLIRVLEQTIQRGNFSIIYFHSNMSSQQSPDLSWLKKLLEIFELKYNNYLKDFNIVHPTFLLKTTLFISKSILGDKGVLSKIIYHENMNKISKLISKCNIPKSIFSYEFSKNEIDNFSFSFDNDVTL", "length": 568 }, "evidence": [ { "id": "A0A8C2LW12", "url": "https://omabrowser.org/oma/group/A0A8C2LW12/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q66H63-1", "protein_name": "Ganglioside-induced differentiation-associated-protein 2", "gene_name": "Gdap2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPLGAPSQFVDVDTLVSWGDSYEDEVNSSDSTAEAFQEDSNRSPFLYNRDINGKVVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLEIHGETIEKVVFAISELEEATYQKLLPLYFPRSLKEESQSLPSLPADIGNAEGEPVVPERQIRISEKPGASEDHEEDEDEGLGVDLSFIGSHAFARMEGDIDKQRKLILQGQLSEAALQKQHQRNYNRWLCQARSEDLSDIASLKALYQTGVDNCGRTVMVVVGRNIPVTLIDMDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDIKYKRNLKAVYFVHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLQQLFSAISPEQIDFPPFVLEYDARENGPYFASYPPSPDL", "length": 497 }, "evidence": [ { "id": "A0A8C2LW12", "url": "https://omabrowser.org/oma/group/A0A8C2LW12/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7JUR6-1", "protein_name": "Protein GDAP2 homolog", "gene_name": "Gdap2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRLDTNSNVDFKAFESSSSSCPVKLDNLATWGGSQKTDTRLPITDYSNLGGPRHNRSPFPLCKDVNNRFVIWDGDMTTLEVDAITNTSDETLTESNSISERIFAVAGNQLREELSTTVKECRTGDVRITRGYNLPAKYVLHTVAPAYREKFKTAAENTLHCCYRNVLCKAKELNLHTIALCNISAHQKSFPADVAAHIALRTIRRYLDKCTLQVVILCVGSSERGTYEVLAPLYFPRDQLEERSALWQLPKDIGGEFGEPQHPDPDRQIRIIRNPQHSVHMRHHLADDDSDVSPHDMEGNSSDLEYGARDMNGLSLNSYSSGLQAQLQRDLDRQHLLSDRPRTGVYENVISEGVEGIEHQERYERLLRRAQVEDLTEVSGIGCLYQSGVDRLGRPVIVFCGKWFPAQNIDLEKALLYLIKLLDPIVKGDYVISYFHTLTSTNNYPSLHWLREVYSVLPYKYKKNLKAFYIVHPTFWTKMMTWWFTTFMAPAIKAKVHSLPGVEHLYSAITKDQLEIPAYITEYDMATNGLHYFNPVPTAS", "length": 540 }, "evidence": [ { "id": "A0A8C2LW12", "url": "https://omabrowser.org/oma/group/A0A8C2LW12/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9DBL2-1", "protein_name": "Ganglioside-induced differentiation-associated protein 2", "gene_name": "Gdap2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LW56-1", "uniprot_ac": "A0A8C2LW56", "uniprot_id": "A0A8C2LW56_CRIGR", "mass": { "chemical_mass": 69670.0, "monoisotopic_mass": 69670.0 }, "refseq": { "ac": "XP_027245299", "name": "nuclear receptor coactivator 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027245299" }, "gene_names": [ { "name": "Ncoa4", "type": "recommended", "evidence": [ { "id": "A0A8C2LW56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LW56" } ] }, { "name": "Ncoa4", "type": "synonym", "evidence": [ { "id": "XP_027245299", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027245299" } ] } ], "protein_names": [ { "name": "Nuclear receptor coactivator 4", "type": "synonym", "evidence": [ { "id": "A0A8C2LW56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LW56/entry#names_and_taxonomy" } ] }, { "name": "nuclear receptor coactivator 4", "type": "synonym", "evidence": [ { "id": "XP_027245299", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027245299" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027245299", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027245299" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LW56", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LW56" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ncoa4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LW56", "locus": {} } ], "crossref": [ { "id": "100756488", "url": "https://www.ncbi.nlm.nih.gov/gene/100756488", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR022174", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022174", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039947", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039947", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756488", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756488", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LW56", "url": "https://www.orthodb.org/?gene=A0A8C2LW56", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17085", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17085", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17085:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17085:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12489", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12489", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027245299", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027245299", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LW56", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LW56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LW56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LW56-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNTSLEQSGCCSNRETLLRCSDARRELELAIGGVLRAEQQIKDNLREVKAQIHSCISRHLECLRSREVWLNEQVDLIYQLKEETLQQQAQQLYWLMGQFSCLIHQLEYTQNKDLAKQVSLCLERLGSLALKPEDSTVLLFEADTSALRQTITTFGSLKTIQIPEHLMAHASSSNIGPFLEKRGYIQVPEQKSASSSTAVSLSEWLLVSKPAIGHQAPYVPSTNPQDWLTPKQTLESSQTSARACSFFSNAWGNRKGLENWLLNSHQQDIPGKPSSSKCNSHCSTSSFSTEVEKVEDVELLDQDELDLSDWLVTPQEPCELKKPENGSCETSEKFKLLFQVFKEPYNVNDWLVKPDSCTNCQGNQPKGVEIENLGNLKCLNDHLEAKKPLSVPSMTTEGWLVQNHQDPCKVEEVCKANEPCTSFADCVCDDNCEKEAVYKWLLKKEGKDKNGMPVESKSEPEKHKESLNLWLYPSRNELTQQAKVPKAKIADSFQVIRNSSLSEWLIGPACKGRGPKEVPSTEDRAGKEMLKGPMATSWCSFNTADWVLPGKKVGNLSQFTSGEDKWLLRKKAQEVFLNSPLQEDRNFRGLPAVCDLFACMQLKVDKDKWLYRTPLQM", "length": 617, "header": "tr|A0A8C2LW56-1|A0A8C2LW56_CRIGR Isoform 1 of Nuclear receptor coactivator 4 OS=Cricetulus griseus OX=10029 GN=Ncoa4 PE=4 SV=1 CANONICAL=A0A8C2LW56-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LW56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LW56/entry#A0A8C2LW56-1", "sequence": { "sequence": "MNTSLEQSGCCSNRETLLRCSDARRELELAIGGVLRAEQQIKDNLREVKAQIHSCISRHLECLRSREVWLNEQVDLIYQLKEETLQQQAQQLYWLMGQFSCLIHQLEYTQNKDLAKQVSLCLERLGSLALKPEDSTVLLFEADTSALRQTITTFGSLKTIQIPEHLMAHASSSNIGPFLEKRGYIQVPEQKSASSSTAVSLSEWLLVSKPAIGHQAPYVPSTNPQDWLTPKQTLESSQTSARACSFFSNAWGNRKGLENWLLNSHQQDIPGKPSSSKCNSHCSTSSFSTEVEKVEDVELLDQDELDLSDWLVTPQEPCELKKPENGSCETSEKFKLLFQVFKEPYNVNDWLVKPDSCTNCQGNQPKGVEIENLGNLKCLNDHLEAKKPLSVPSMTTEGWLVQNHQDPCKVEEVCKANEPCTSFADCVCDDNCEKEAVYKWLLKKEGKDKNGMPVESKSEPEKHKESLNLWLYPSRNELTQQAKVPKAKIADSFQVIRNSSLSEWLIGPACKGRGPKEVPSTEDRAGKEMLKGPMATSWCSFNTADWVLPGKKVGNLSQFTSGEDKWLLRKKAQEVFLNSPLQEDRNFRGLPAVCDLFACMQLKVDKDKWLYRTPLQM", "length": 617, "header": "tr|A0A8C2LW56-1|A0A8C2LW56_CRIGR Isoform 1 of Nuclear receptor coactivator 4 OS=Cricetulus griseus OX=10029 GN=Ncoa4 PE=4 SV=1 CANONICAL=A0A8C2LW56-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LW56", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LW56" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"https://www.ebi.ac.uk/QuickGO/term/GO:0006879", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LW56", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LW56" } ], "pmid": "" }, { "name": "response to hormone", "id": "GO:0009725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009725", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LW56", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LW56" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 2, "end_pos": 4, "annotation": "n_glycosylation_sequon" }, { "start_pos": 325, "end_pos": 327, "annotation": "n_glycosylation_sequon" }, { "start_pos": 498, "end_pos": 500, "annotation": "n_glycosylation_sequon" }, { "start_pos": 555, "end_pos": 557, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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73345.0, "monoisotopic_mass": 73345.0 }, "refseq": { "ac": "XP_007611037", "name": "solute carrier family 22 member 23 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007611037" }, "gene_names": [ { "name": "Slc22a23", "type": "recommended", "evidence": [ { "id": "A0A8C2LWG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWG7" } ] }, { "name": "Slc22a23", "type": "synonym", "evidence": [ { "id": "XP_007611037", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007611037" } ] } ], "protein_names": [ { "name": "Solute carrier family 22 member 23 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A8C2LWG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWG7/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 22 member 23 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_007611037", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007611037" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 728 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613650.1) and transcript sequence (IACG01040015.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_007611037.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007611037", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007611037" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LWG7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWG7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Slc22a23", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWG7", "locus": {} } ], "crossref": [ { "id": "cd17444", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17444", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100762294", "url": "https://www.ncbi.nlm.nih.gov/gene/100762294", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005829", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005829", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762294", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762294", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LWG7", "url": "https://www.orthodb.org/?gene=A0A8C2LWG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7GYP0", "url": "https://www.orthodb.org/?gene=A0A9J7GYP0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24064", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24064", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00083", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00083", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_007611037", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007611037", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LWG7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LWG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWG7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GUQ7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GUQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GUQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GUQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GX09", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GX09-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GX09-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GXD7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GXD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GXD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GXD7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GYP0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GYP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GYP0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAIDRRREAAGSGAGRQPPPAEENGSLPPGDAAASAPLGGRAGSGGSAEIQPLPALHPSGGPHSSCCAAAAAPSLLLLDYDGSVLPFLGGLGGGYQKTLVVLTWIPALFIGFSQFSDSFLLDQPNFWCRGAGKGTELAGSTVTGRWGDMGNWTSPPANPFSTAAWGTASNRSNSSDTPPLPSPPGKGNNDSNCDCHAWDYGIRTGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGVILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFEAAKKLILYITQKNCVSPESDIKGVMPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPLLENFYADYYTMASIALASCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENIANGEHYTRQPLLPHKKGEQPLLLTNAELKDYSGLHDVAAVGDGLPEGATANGMKSM", "length": 681, "header": "tr|A0A8C2LWG7-1|A0A8C2LWG7_CRIGR Isoform 1 of Solute carrier family 22 member 23 isoform X2 OS=Cricetulus griseus OX=10029 GN=Slc22a23 PE=4 SV=1 CANONICAL=A0A8C2LWG7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LWG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWG7/entry#A0A8C2LWG7-1", "sequence": { "sequence": "MAIDRRREAAGSGAGRQPPPAEENGSLPPGDAAASAPLGGRAGSGGSAEIQPLPALHPSGGPHSSCCAAAAAPSLLLLDYDGSVLPFLGGLGGGYQKTLVVLTWIPALFIGFSQFSDSFLLDQPNFWCRGAGKGTELAGSTVTGRWGDMGNWTSPPANPFSTAAWGTASNRSNSSDTPPLPSPPGKGNNDSNCDCHAWDYGIRTGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGVILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFEAAKKLILYITQKNCVSPESDIKGVMPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPLLENFYADYYTMASIALASCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENIANGEHYTRQPLLPHKKGEQPLLLTNAELKDYSGLHDVAAVGDGLPEGATANGMKSM", "length": 681, "header": "tr|A0A8C2LWG7-1|A0A8C2LWG7_CRIGR Isoform 1 of Solute carrier family 22 member 23 isoform X2 OS=Cricetulus griseus OX=10029 GN=Slc22a23 PE=4 SV=1 CANONICAL=A0A8C2LWG7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GUQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWG7/entry#A0A9J7GUQ7-1", "sequence": { "sequence": "MAIDRRREAAGSGAGRQPPPAEENGSLPPGDAAASAPLGGRAGSGGSAEIQPLPALHPSGGPHSSCCAAAAAPSLLLLDYDGSVLPFLGGLGGGYQKTLVVLTWIPALFIGFSQFSDSFLLDQPNFWCRGAGKGTELAGSTVTGRWGDMGNWTSPPANPFSTAAWGTASNRSNSSDTPPLPSPPGKGNNDSNCDCHAWDYGIRTGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGVILTLYALR", "length": 300, "header": "tr|A0A9J7GUQ7-1|A0A9J7GUQ7_CRIGR Computationally mapped isoform of Solute carrier family 22 member 23 isoform X5 OS=Cricetulus griseus OX=10029 GN=Slc22a23 PE=4 SV=1 CANONICAL=A0A8C2LWG7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GX09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWG7/entry#A0A9J7GX09-1", "sequence": { "sequence": "MAIDRRREAAGSGAGRQPPPAEENGSLPPGDAAASAPLGGRAGSGGSAEIQPLPALHPSGGPHSSCCAAAAAPSLLLLDYDGSVLPFLGGLGGGYQKTLVVLTWIPALFIGFSQFSDSFLLDQPNFWCRGAGKGTELAGSTVTGRWGDMGNWTSPPANPFSTAAWGTASNRSNSSDTPPLPSPPGKGNNDSNCDCHAWDYGIRTGLVQNVVSKWDLVCDNAWKVHIAKFSLLVGLIFGYLITGCIADWVGRRPVLLFSIIFILIFGLTVALSVNVTMFSTLRFFEGFCLAGVILTLYALRMASYL", "length": 305, "header": "tr|A0A9J7GX09-1|A0A9J7GX09_CRIGR Computationally mapped isoform of Solute carrier family 22 member 23 isoform X4 OS=Cricetulus griseus OX=10029 GN=Slc22a23 PE=4 SV=1 CANONICAL=A0A8C2LWG7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GXD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWG7/entry#A0A9J7GXD7-1", "sequence": { "sequence": "MFSTLRFFEGFCLAGVILTLYALRIELCPPGKRFMITMVASFVAMAGQFLMPGLAALCRDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFEAAKKLILYITQKNCVSPESDIKGVMPELEKELSRRPKKVCIVKVVGTRNLWKNIVVLCVNSLTGYGIHHCFARSMMGHEVKVPLLENFYADYYTMASIALASCLAMCVVVRFLGRRGGLLLFMILTALASLLQLGLLNLIGKYSQHPDSGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACCTLICIICILLLPESRDQNLPENIANGEHYTRQPLLPHKKGEQPLLLTNAELKDYSGLHDVAAVGDGLPEGATANGMKSM", "length": 405, "header": "tr|A0A9J7GXD7-1|A0A9J7GXD7_CRIGR Computationally mapped isoform of Solute carrier family 22 member 23 isoform X3 OS=Cricetulus griseus OX=10029 GN=Slc22a23 PE=4 SV=1 CANONICAL=A0A8C2LWG7-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GYP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWG7/entry#A0A9J7GYP0-1", "sequence": { "sequence": "MAIDRRREAAGSGAGRQPPPAEENGSLPPGDAAASAPLGGRAGSGGSAEIQPLPALHPSGGPHSSCCAAAAAPSLLLLDYDGSVLPFLGGLGGGYQKTLVVLTWIPALFIGFSQFSDSFLLDQPNFWCRGAGKGTELAGSTVTGRWGDMGNWTSPPANPFSTAAWGTASNRSNSSDTPPLPSPPGKGNNDSNCDCHAWDYGIRTGLVQNVVSKHQDLMVRFAACTGLGQPGLQKTTQFTRDVKSIREVMTWR", "length": 252, "header": "tr|A0A9J7GYP0-1|A0A9J7GYP0_CRIGR Computationally mapped isoform of Solute carrier family 22 member 23 isoform X6 OS=Cricetulus griseus OX=10029 GN=Slc22a23 PE=4 SV=1 CANONICAL=A0A8C2LWG7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LWG7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWG7" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LWG7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWG7" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762294", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762294", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LWG7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWG7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LWG7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWG7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 173, "end_pos": 175, "annotation": "n_glycosylation_sequon" }, { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 24, "end_pos": 26, "annotation": "n_glycosylation_sequon" }, { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LWG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWG7" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 162, "end_pos": 617, "start_aa": "Thr", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 151, "end_pos": 153 }, { "start_pos": 170, "end_pos": 172 }, { "start_pos": 173, "end_pos": 175 }, { "start_pos": 189, "end_pos": 191 }, { "start_pos": 24, "end_pos": 26 }, { "start_pos": 274, "end_pos": 276 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", 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"https://www.uniprot.org/uniprotkb/A0A8C2LWK2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 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{ "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { 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"https://www.ncbi.nlm.nih.gov/protein/XP_003509086" }, "gene_names": [ { "name": "Gemin8", "type": "recommended", "evidence": [ { "id": "A0A8C2LWK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWK8" } ] }, { "name": "Gemin8", "type": "synonym", "evidence": [ { "id": "XP_003509086", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509086" } ] } ], "protein_names": [ { "name": "Gem-associated protein 8", "type": "synonym", "evidence": [ { "id": "A0A8C2LWK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWK8/entry#names_and_taxonomy" } ] }, { "name": "gem-associated protein 8", "type": "synonym", "evidence": [ { "id": "XP_003509086", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509086" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614633.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003509086", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509086" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LWK8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWK8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Gemin8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWK8", "locus": {} } ], "crossref": [ { "id": "100765564", "url": "https://www.ncbi.nlm.nih.gov/gene/100765564", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR034754", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034754", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765564", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765564", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QYFAHTE", "url": "https://omabrowser.org/oma/group/QYFAHTE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LWK8", "url": "https://www.orthodb.org/?gene=A0A8C2LWK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16238", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16238", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16238:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16238:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15348", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15348", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003509086", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509086", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LWK8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LWK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWK8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSKWRTTASWYSHPVYARYWRHYHHAMAWMQSHQRAYKKSRDSYFTSPWFSPYGVLPWSSLDYEAGHPWNYQGQHMAWQESPYNVSHLKSSGQPLYSNSRTQTSAREYEAPQEEEEIESDSDNEVECDLSNMEITEELRQYFAETERHREERRRQQQLDAERLDDYVNADHGLYYNHHRSVEPPSEKPGERRQAEMKRLYGDSAPKILAMEAAVQLSFDKYCDKKQPKYWPVIPLKF", "length": 238, "header": "tr|A0A8C2LWK8-1|A0A8C2LWK8_CRIGR Isoform 1 of Gem-associated protein 8 OS=Cricetulus griseus OX=10029 GN=Gemin8 PE=4 SV=1 CANONICAL=A0A8C2LWK8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LWK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWK8/entry#A0A8C2LWK8-1", "sequence": { "sequence": "MTSKWRTTASWYSHPVYARYWRHYHHAMAWMQSHQRAYKKSRDSYFTSPWFSPYGVLPWSSLDYEAGHPWNYQGQHMAWQESPYNVSHLKSSGQPLYSNSRTQTSAREYEAPQEEEEIESDSDNEVECDLSNMEITEELRQYFAETERHREERRRQQQLDAERLDDYVNADHGLYYNHHRSVEPPSEKPGERRQAEMKRLYGDSAPKILAMEAAVQLSFDKYCDKKQPKYWPVIPLKF", "length": 238, "header": "tr|A0A8C2LWK8-1|A0A8C2LWK8_CRIGR Isoform 1 of Gem-associated protein 8 OS=Cricetulus griseus OX=10029 GN=Gemin8 PE=4 SV=1 CANONICAL=A0A8C2LWK8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"url": "https://omabrowser.org/oma/group/A0A8C2LWK8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1SQV2-1", "protein_name": "Gem nuclear organelle associated protein 8", "gene_name": "GEMIN8", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAETAPGQAPESWCSHPVYARYWHHYHQAMAWMRSHQSTYRKAVESFFSSPWYFPPAGLAQGAYAQEGGSPWPDSEQPPAPGGSCHQYPHAGGPEPGPRGREEPAWSAEEEEEEQEEESESDDGGIECDLSNMEITEELRQYFAQTERHREERRRQQQLDAARLDDYVNADHDLYCDTRRSALPPAERPGERRAAEMRRLYGASAAKIQAMEAAVQLSFDKHCDRKQPKYWPVIPLKF", "length": 239 }, "evidence": [ { "id": "A0A8C2LWK8", "url": "https://omabrowser.org/oma/group/A0A8C2LWK8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q1LZ79-1", "protein_name": "Gem-associated protein 8", "gene_name": "GEMIN8", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": 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This record is derived from a genomic sequence (NW_003613874.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003502070", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502070" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LWM0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWM0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100773019", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWM0", "locus": {} } ], "crossref": [ { "id": "100773019", "url": "https://www.ncbi.nlm.nih.gov/gene/100773019", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000232", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000232", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773019", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773019", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LWM0", "url": "https://www.orthodb.org/?gene=A0A8C2LWM0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10015:SF336", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10015:SF336", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00447", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00447", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003502070", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502070", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LWM0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LWM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWM0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEAPSEILDASGHDVSADSETPSSPPLCDDTGQGDSDLWAIIEESAFQVLAQRFLIKRSSHSLCASEPDEDSNLFSMTFPRKLWKIVGSDKFKSIWWDEAGTYIVINEELFKKEVLERKAPFRIFETDSMKSLVRQLNLYGFRKMRQNFQRSASLPDFLAEEKGVSASCKLQFYQNPNFLRDCPHLIERMKRRIGIKTASRGAAPSPPEFKNKHFSPDLDNMDDQSLGVAVQTRKRNLLSSPSISNVYLRQKSSTAQGDTDTMDGIRRDFSLATSSSFRPPEKILTHHPAPLNEVSPLHMDSQRIYTQANDSTMNFIITSIQNHRDVSHLWNSCIEMQAEPSFQPGYPHFSSSSSTYSDSKAIGESKLPIYKERVVSTTLASALNHHPSS", "length": 391, "header": "tr|A0A8C2LWM0-1|A0A8C2LWM0_CRIGR Isoform 1 of Heat shock transcription factor, Y-linked-like OS=Cricetulus griseus OX=10029 GN=LOC100773019 PE=3 SV=1 CANONICAL=A0A8C2LWM0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LWM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWM0/entry#A0A8C2LWM0-1", "sequence": { "sequence": "MAEAPSEILDASGHDVSADSETPSSPPLCDDTGQGDSDLWAIIEESAFQVLAQRFLIKRSSHSLCASEPDEDSNLFSMTFPRKLWKIVGSDKFKSIWWDEAGTYIVINEELFKKEVLERKAPFRIFETDSMKSLVRQLNLYGFRKMRQNFQRSASLPDFLAEEKGVSASCKLQFYQNPNFLRDCPHLIERMKRRIGIKTASRGAAPSPPEFKNKHFSPDLDNMDDQSLGVAVQTRKRNLLSSPSISNVYLRQKSSTAQGDTDTMDGIRRDFSLATSSSFRPPEKILTHHPAPLNEVSPLHMDSQRIYTQANDSTMNFIITSIQNHRDVSHLWNSCIEMQAEPSFQPGYPHFSSSSSTYSDSKAIGESKLPIYKERVVSTTLASALNHHPSS", "length": 391, "header": "tr|A0A8C2LWM0-1|A0A8C2LWM0_CRIGR Isoform 1 of Heat shock transcription factor, Y-linked-like OS=Cricetulus griseus OX=10029 GN=LOC100773019 PE=3 SV=1 CANONICAL=A0A8C2LWM0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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This record is derived from a genomic sequence (NW_003615456.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027240306.1. 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LWS5-1", "uniprot_ac": "A0A8C2LWS5", "uniprot_id": "A0A8C2LWS5_CRIGR", "mass": { "chemical_mass": 28180.0, "monoisotopic_mass": 28180.0 }, "refseq": { "ac": "XP_035306787", "name": "leucine-rich repeat-containing protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306787" }, "gene_names": [ { "name": "Lrrc3", "type": "recommended", "evidence": [ { "id": "A0A8C2LWS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWS5" } ] }, { "name": "Lrrc3", "type": "synonym", "evidence": [ { "id": "XP_035306787", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306787" } ] } ], "protein_names": [ { "name": "Leucine-rich repeat-containing protein 3", "type": "synonym", "evidence": [ { "id": "A0A8C2LWS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWS5/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat-containing protein 3", "type": "synonym", "evidence": [ { "id": "XP_035306787", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306787" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276806.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035306787", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306787" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LWS5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWS5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Lrrc3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWS5", "locus": {} } ], "crossref": [ { "id": "100761264", "url": "https://www.ncbi.nlm.nih.gov/gene/100761264", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761264", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761264", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QCPDHAG", "url": "https://omabrowser.org/oma/group/QCPDHAG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LWS5", "url": "https://www.orthodb.org/?gene=A0A8C2LWS5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24366", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24366", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24366:SF171", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24366:SF171", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01462", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01462", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035306787", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035306787", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LWS5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LWS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWS5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGPRGRQSPSSPLAPTQGSCFFILFCLHLGTSCPQACQCPDHAGAVAVHCSSKGLQEIPRDIPVDTVLLKLDANRISRVPNGAFQNLPQLRELDLSHNAIEAIGPAAFSGLAGGLRLLDLSHNRIRRIPKDALGKLSAKIRLSHNPLHCECALQEALWELKLDPDSVDEIACHTSAQEQFVGKPLIQVLDSGASFCSTHRKTTDVAMLVTMFCWFTMVIAYVVYYVRHNQEDARRHLEYLKSLPSAPVSKEPLSPVP", "length": 257, "header": "tr|A0A8C2LWS5-1|A0A8C2LWS5_CRIGR Isoform 1 of Leucine-rich repeat-containing protein 3 OS=Cricetulus griseus OX=10029 GN=Lrrc3 PE=3 SV=1 CANONICAL=A0A8C2LWS5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LWS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWS5/entry#A0A8C2LWS5-1", "sequence": { "sequence": "MGPRGRQSPSSPLAPTQGSCFFILFCLHLGTSCPQACQCPDHAGAVAVHCSSKGLQEIPRDIPVDTVLLKLDANRISRVPNGAFQNLPQLRELDLSHNAIEAIGPAAFSGLAGGLRLLDLSHNRIRRIPKDALGKLSAKIRLSHNPLHCECALQEALWELKLDPDSVDEIACHTSAQEQFVGKPLIQVLDSGASFCSTHRKTTDVAMLVTMFCWFTMVIAYVVYYVRHNQEDARRHLEYLKSLPSAPVSKEPLSPVP", "length": 257, "header": "tr|A0A8C2LWS5-1|A0A8C2LWS5_CRIGR Isoform 1 of Leucine-rich repeat-containing protein 3 OS=Cricetulus griseus OX=10029 GN=Lrrc3 PE=3 SV=1 CANONICAL=A0A8C2LWS5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 16, "start_aa": "Thr", "end_pos": 16, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr16", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LWS5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWS5" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LWS5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWS5" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761264", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761264", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8W4FKE3-1", "protein_name": "Leucine-rich repeat-containing protein 3", "gene_name": "LRRC3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGPVGRHGPSALPVPTGGSCLLLLFCLRLGASCPQSCQCPDHAGAVAVHCSARGLQEIPKDIPLDTVLLKLDANKIARIPNGAFQHLSHLRELDLSQNAIETIGPAAFSGLAGGLRLLDLSHNRIRRIPKDALGKLSAKIRLSHNPLHCECALQEALWELKLDPDSVDEIACHTSVQEEYVGKPLIQALDAGVSFCSVHHKTTDVAMLVTMFGWFAMVITYVVYYVRQNQEDARRHLEYLKSLPSTPVSKDPVSPAP", "length": 257 }, "evidence": [ { "id": "A0A8C2LWS5", "url": "https://omabrowser.org/oma/group/A0A8C2LWS5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A6H793-1", "protein_name": "Leucine-rich repeat-containing protein 3", "gene_name": "LRRC3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGPTGRQSPSSLPVPAGGPCLLLLFCLRLGASCPQNCQCPDHAGAVAVHCSARGLQEVPRDIPADTVLLKLDANKIARIPNGAFQHLHQLRELDLSQNAIETIGPAAFSGLAGGLRLLDLSHNRLRRIPKDALGKLSAKIRLAHNPLHCECALQEALWELKLDPDSVDEIACHTSVQEEYVGKPLIQALDSGVSFCSVHHKTTDVAMLVTMFGWFAMVITYVVYYVRQNQEDARRHLEYLKSLPSTPMSKDPTSSAP", "length": 257 }, "evidence": [ { "id": "A0A8C2LWS5", "url": "https://omabrowser.org/oma/group/A0A8C2LWS5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A8WHP9-1", "protein_name": "Leucine-rich repeat-containing protein 3", "gene_name": "lrrc3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTFPAGAYVLRKVFIPHGCPLIFRLLLAVICLSVPSFACPKSCHCSERNSLTVVQCSSRNLEEIPPDLPHDTVSLQLSSNHITKIPNQAFKNLPWLQELDLSRNAIETVDAGAFKGVSESLRTLDLSHNHMQGVPKEAFARLHAKISLSNNPWHCECTLQEVLRELRLDPETVNEVSCHTSDQEKYAGKPVIQVLDSGINFCNFHHKTTDVAMFVTMFGWFTMVIAYVIYYVRHNQEDARRHLEYLKSLPSSSQISKDFDTISTVL", "length": 266 }, "evidence": [ { "id": "A0A8C2LWS5", "url": "https://omabrowser.org/oma/group/A0A8C2LWS5/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P59034-1", "protein_name": "Leucine-rich repeat-containing protein 3", "gene_name": "Lrrc3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGPRGRQSPSATLAPSQGSCFFILFCLRLGASCPQACQCPDHAGAVAVHCSSRGLQEIPRDIPADTVLLKLDANRISRVPNGAFQHLPQLRELDLSHNAIEAIGPAAFSGLAGGLRLLDLSHNRIRRIPKDALGKLSAKIRLSHNPLHCECALQEALWELKLDPDSVDEIACHTSAQEQFVGKPLIQVLDSGASFCSTHRKTTDVAMLVTMFGWFTMVIAYVVYYVRHNQEDARRHLEYLKSLPSAPVSKEPLSPVP", "length": 257 }, "evidence": [ { "id": "A0A8C2LWS5", "url": "https://omabrowser.org/oma/group/A0A8C2LWS5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P59035-1", "protein_name": "Leucine-rich repeat-containing protein 3", "gene_name": "Lrrc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGPRGRQSPSSPLAPSQGSCFFILFCLRLGASCPQSCQCPDHAGAVAVHCSSRGLQEIPRDIPANTVLLKLDANRISRVPNGAFQHLPQLRELDLSHNAIEAIGPAAFSGLAGGLRLLDLSHNRIRRIPKDALGKLSAKIRLSHNPLHCECALQEALWELKLDPDSVDEIACHTSAQEQFVGKPLIQVLDSGASFCSTHRKTTDVAMLVTMFGWFTMVIAYVVYYVRHNQEDARRHLEYLKSLPSAPVSKEPLSPVP", "length": 257 }, "evidence": [ { "id": "A0A8C2LWS5", "url": "https://omabrowser.org/oma/group/A0A8C2LWS5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BY71-1", "protein_name": "Leucine-rich repeat-containing protein 3", "gene_name": "LRRC3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGTVRPPRPSLLLVSTRESCLFLLFCLHLGAACPQPCRCPDHAGAVAVFCSLRGLQEVPEDIPANTVLLKLDANKISHLPDGAFQHLHRLRELDLSHNAIEAIGSATFAGLAGGLRLLDLSYNRIQRIPKDALGKLSAKIRLSHNPLHCECALQEALWELKLDPDSVDEIACHTSVQEEFVGKPLVQALDAGASLCSVPHRTTDVAMLVTMFGWFAMVIAYVVYYVRHNQEDARRHLEYLKSLPSAPASKDPIGPGP", "length": 257 }, "evidence": [ { "id": "A0A8C2LWS5", "url": "https://omabrowser.org/oma/group/A0A8C2LWS5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LWS5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWS5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LWS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWS5" }, { "id": "SM00013", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00013" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRNT", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 68, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 16 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LWY0-1", "uniprot_ac": "A0A8C2LWY0", "uniprot_id": "A0A8C2LWY0_CRIGR", "mass": { "chemical_mass": 33206.0, "monoisotopic_mass": 33206.0 }, "refseq": { "ac": "XP_027280852", "name": "tryptase gamma-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280852" }, "gene_names": [ { "name": "LOC113836642", "type": "recommended", "evidence": [ { "id": "A0A8C2LWY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWY0" } ] }, { "name": "LOC113836642", "type": "synonym", "evidence": [ { "id": "XP_027280852", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280852" } ] } ], "protein_names": [ { "name": "Tryptase gamma-like", "type": "synonym", "evidence": [ { "id": "A0A8C2LWY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWY0/entry#names_and_taxonomy" } ] }, { "name": "tryptase gamma-like", "type": "synonym", "evidence": [ { "id": "XP_027280852", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280852" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027280852", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280852" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LWY0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWY0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC113836642", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWY0", "locus": {} } ], "crossref": [ { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "113836642", "url": "https://www.ncbi.nlm.nih.gov/gene/113836642", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:113836642", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113836642", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CGQPQHS", "url": "https://omabrowser.org/oma/group/CGQPQHS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LWY0", "url": "https://www.orthodb.org/?gene=A0A8C2LWY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24253", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24253", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24253:SF170", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24253:SF170", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027280852", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280852", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LWY0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LWY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWY0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPLGPRGFLLLLAVPGCGQPQVSRAGSRIVGGQAAPAGTWPWQASLRLQKVHVCGGSLLSPEWVLTAAHCFSGSVNSSDYQVHLGELTITLSPHFSTVKKIILYSSPPGPPGSSGDIALVQLGTPVALSNWVQPVCLPEASADFYPGMDCWVTGWGHTHEGEPLKPPYNLQEAEVSVVDVESCSQAYSSPNGTIIQPDMLCAQGPGDACQDDSGGPLVCQVAGIWQQAGVVSWGEGCGRPDRPGVYTRVTAYVNWIHHHIPESGGSGIQGFSWIPLLAGLFLPSLLLLLVSGVLMAKCWLGQCWLGSPSHPTSDL", "length": 315, "header": "tr|A0A8C2LWY0-1|A0A8C2LWY0_CRIGR Isoform 1 of Tryptase gamma-like OS=Cricetulus griseus OX=10029 GN=LOC113836642 PE=4 SV=1 CANONICAL=A0A8C2LWY0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LWY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWY0/entry#A0A8C2LWY0-1", "sequence": { "sequence": "MPLGPRGFLLLLAVPGCGQPQVSRAGSRIVGGQAAPAGTWPWQASLRLQKVHVCGGSLLSPEWVLTAAHCFSGSVNSSDYQVHLGELTITLSPHFSTVKKIILYSSPPGPPGSSGDIALVQLGTPVALSNWVQPVCLPEASADFYPGMDCWVTGWGHTHEGEPLKPPYNLQEAEVSVVDVESCSQAYSSPNGTIIQPDMLCAQGPGDACQDDSGGPLVCQVAGIWQQAGVVSWGEGCGRPDRPGVYTRVTAYVNWIHHHIPESGGSGIQGFSWIPLLAGLFLPSLLLLLVSGVLMAKCWLGQCWLGSPSHPTSDL", "length": 315, "header": "tr|A0A8C2LWY0-1|A0A8C2LWY0_CRIGR Isoform 1 of Tryptase gamma-like OS=Cricetulus griseus OX=10029 GN=LOC113836642 PE=4 SV=1 CANONICAL=A0A8C2LWY0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LWY0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWY0" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LWY0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWY0" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:113836642", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:113836642", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AAZ3-1", "protein_name": "Tryptase gamma 1", "gene_name": "Tpsg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALGPYCGFLLLLAVPGISCEALQSGCGQPQVSHAGSRIVGGHAAQAGAWPWQASLRLQKVHVCGGSLLSPEWVLTAAHCFSGSVNSSDYEVHLGELTITLSPHFSTVKQIIMYSSAPGPPGSSGDIALVQLATPVALSSQVQPVCLPEASADFHPGMQCWVTGWGYTQEGEPLKPPYNLQEAKVSVVDVETCSQAYSSSNGSLIQSDMLCAWGPGDACQDDSGGPLVCRVAGIWQQAGVVSWGEGCGRPDRPGVYARVTAYVNWIHRHILEPGGSGMQGLSWIPLLAGLFLPSLFLLLVSGVVMAKYWLGSPSHPALEF", "length": 320 }, "evidence": [ { "id": "A0A8C2LWY0", "url": "https://omabrowser.org/oma/group/A0A8C2LWY0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9NRR2-1", "protein_name": "Tryptase gamma", "gene_name": "TPSG1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALGACGLLLLLAVPGVSLRTLQPGCGRPQVSDAGGRIVGGHAAPAGAWPWQASLRLRRVHVCGGSLLSPQWVLTAAHCFSGSLNSSDYQVHLGELEITLSPHFSTVRQIILHSSPSGQPGTSGDIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSLREVKVSVVDTETCRRDYPGPGGSILQPDMLCARGPGDACQDDSGGPLVCQVNGAWVQAGTVSWGEGCGRPNRPGVYTRVPAYVNWIRRHITASGGSESGYPRLPLLAGFFLPGLFLLLVSCVLLAKCLLHPSADGTPFPAPD", "length": 321 }, "evidence": [ { "id": "A0A8C2LWY0", "url": "https://omabrowser.org/oma/group/A0A8C2LWY0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QUL7-1", "protein_name": "Tryptase gamma", "gene_name": "Tpsg1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGPNCGILLFLAVSGCGHPQVSNSGSRIVGGHAAPAGTWPWQASLRLHKVHVCGGSLLSPEWVLTAAHCFSGSVNSSDYQVHLGELTVTLSPHFSTVKRIIMYTGSPGPPGSSGDIALVQLSSPVALSSQVQPVCLPEASADFYPGMQCWVTGWGYTGEGEPLKPPYNLQEAKVSVVDVKTCSQAYNSPNGSLIQPDMLCARGPGDACQDDSGGPLVCQVAGTWQQAGVVSWGEGCGRPDRPGVYARVTAYVNWIHHHIPEAGGSGMQGLPWAPLLAALFWPSLFLLLVSGVLMAKYWLSSPSHAASEL", "length": 311 }, "evidence": [ { "id": "A0A8C2LWY0", "url": "https://omabrowser.org/oma/group/A0A8C2LWY0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LWY0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWY0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LWY0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWY0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LWY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LWY0" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 261, "start_aa": "Ile", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 191, "end_pos": 193 }, { "start_pos": 76, "end_pos": 78 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2M026-1", "uniprot_ac": "A0A8C2M026", "uniprot_id": "A0A8C2M026_CRIGR", "mass": { "chemical_mass": 75229.0, "monoisotopic_mass": 75229.0 }, "refseq": { "ac": "XP_027246694", "name": "sec1 family domain-containing protein 2 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246694" }, "gene_names": [ { "name": "Scfd2", "type": "recommended", "evidence": [ { "id": "A0A8C2M026", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M026" } ] }, { "name": "Scfd2", "type": "synonym", "evidence": [ { "id": "XP_027246694", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246694" } ] } ], "protein_names": [ { "name": "Sec1 family domain-containing protein 2 isoform X3", "type": "synonym", "evidence": [ { "id": "A0A8C2M026", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M026/entry#names_and_taxonomy" } ] }, { "name": "sec1 family domain-containing protein 2 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027246694", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246694" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_023276807.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027246694", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246694" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M026", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M026" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Scfd2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M026", "locus": {} } ], "crossref": [ { "id": "100755789", "url": "https://www.ncbi.nlm.nih.gov/gene/100755789", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001619", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001619", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027482", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027482", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755789", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755789", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2M026", "url": "https://www.orthodb.org/?gene=A0A8C2M026", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11679", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11679", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00995", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00995", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027246694", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027246694", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LX22", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LX22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LX22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LX22-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M026", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M026", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M026-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M026-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F301", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F301", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F301-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F301-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J890", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J890", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7J890-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7J890-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBU7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KBU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KBU7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSAGVLSFAQQGWEQVLAKVKWSVVYLDAACAESLHWSCGSSRLLEAVKGPACNLREFEPQAIGGGAQQPRAVFVLSCLLKGRTVDTLQDIIRRSHFQYCVVVTAVSHAVHLTANHVPAAAAAELEGQQPVFEQLEEKLCEWMGNVNYTAEVLHVPLLLAPAAPHLAFTPAFATLFPLLPRDVHLLNSARPDKRRLINLSEVDATSLTPELLLHIRCLVSGLSSLCEHLGVREECFAVGALSRVIATDLANYAPAKNRRKTATGRASVVFVDRTLDLTGAVGHHGDNLIEKIISVLPQLPGHTSDVMVNMVELTAVQTMEENQNVIAPGCLAQSNDTSGKALWEALLNTKHKEAVMEVRRHLVEAASRENLPIRMSMGRVTPGQLMSYIQLFKNNLKALTNHCGLLQLGMATVQTLKHPQTAKWDNFLAFERLLLQSLGDSTMAVVLNQLLPMIKSPSQRTSDDYSSEELLILLIYIYSVTGEFVLDKDLREAEDRVKKALAHVFSEESELSPLLQKITGCDSAINLTFPKSQLAVNDIFTSLQEIAGARTLMRQFKSVYVPGNHTHQASYKPLLKQVVEEIFNPEKPDPTDIEHTSSGLTDLLKTGFSMFMKVSRPHPSDHPLLILFVVGGITVSEAKMVKDLVASLKTGTQVMVLSTRLLKPLNIPELLFATDRLHPDLGF", "length": 684, "header": "tr|A0A8C2M026-1|A0A8C2M026_CRIGR Isoform 1 of Sec1 family domain-containing protein 2 isoform X3 OS=Cricetulus griseus OX=10029 GN=Scfd2 PE=3 SV=1 CANONICAL=A0A8C2M026-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LX22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M026/entry#A0A8C2LX22-1", "sequence": { "sequence": "MSSAGVLSFAQQGWEQVLAKVKWSVVYLDAACAESLHWSCGSSRLLEAVKGPACNLREFEPQAIGGGAQQPRAVFVLSCLLKGRTVDTLQDIIRRSHFQYCVVVTAVSHAVHLTANHVPAAAAAELEGQQPVFEQLEEKLCEWMGNVNYTAEVLHVPLLLAPAAPHLAFTPAFATLFPLLPRDVHLLNSARPDKRRLINLSEVDATSLTPELLLHIRCLVSGLSSLCEHLGVREECFAVGALSRVIATDLANYAPAKNRRKTATGRASVVFVDRTLDLTGAVGHHGDNLIEKIISVLPQLPGHTSDVMVNMVELTAVQTMEENQNVIAPGCLAQSNDTSGKALWEALLNTKHKEAVMEVRRHLVEAASRENLPIRMSMGRVTPGQLMSYIQLFKNNLKALTNHCGLLQLGMATVQTLKHPQTAKWDNFLAFERLLLQSLGDSTMAVVLNQLLPMIKSPSQRTSDDYSSEELLILLIYIYSVTGEFVLDKDLREAEDRVKKALAHVFSEESELSPLLQKITGCDSAINLTFPKSQLAVNDIFTSLQEIAGARTLMRQFKSVYVPGNHTHQASYKPLLKQVVEEIFNPEKPDPTDIEHTSSGLTDLLKTGFSMFMKVMVLSTRLLKPLNIPELLFATDRLHPDLGF", "length": 644, "header": "tr|A0A8C2LX22-1|A0A8C2M026_CRIGR Computationally mapped isoform of Sec1 family domain-containing protein 2 isoform X3 OS=Cricetulus griseus OX=10029 GN=Scfd2 PE=3 SV=1 CANONICAL=A0A8C2M026-1" }, "locus": {} }, { "isoform_ac": "A0A8C2M026-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M026/entry#A0A8C2M026-1", "sequence": { "sequence": "MSSAGVLSFAQQGWEQVLAKVKWSVVYLDAACAESLHWSCGSSRLLEAVKGPACNLREFEPQAIGGGAQQPRAVFVLSCLLKGRTVDTLQDIIRRSHFQYCVVVTAVSHAVHLTANHVPAAAAAELEGQQPVFEQLEEKLCEWMGNVNYTAEVLHVPLLLAPAAPHLAFTPAFATLFPLLPRDVHLLNSARPDKRRLINLSEVDATSLTPELLLHIRCLVSGLSSLCEHLGVREECFAVGALSRVIATDLANYAPAKNRRKTATGRASVVFVDRTLDLTGAVGHHGDNLIEKIISVLPQLPGHTSDVMVNMVELTAVQTMEENQNVIAPGCLAQSNDTSGKALWEALLNTKHKEAVMEVRRHLVEAASRENLPIRMSMGRVTPGQLMSYIQLFKNNLKALTNHCGLLQLGMATVQTLKHPQTAKWDNFLAFERLLLQSLGDSTMAVVLNQLLPMIKSPSQRTSDDYSSEELLILLIYIYSVTGEFVLDKDLREAEDRVKKALAHVFSEESELSPLLQKITGCDSAINLTFPKSQLAVNDIFTSLQEIAGARTLMRQFKSVYVPGNHTHQASYKPLLKQVVEEIFNPEKPDPTDIEHTSSGLTDLLKTGFSMFMKVSRPHPSDHPLLILFVVGGITVSEAKMVKDLVASLKTGTQVMVLSTRLLKPLNIPELLFATDRLHPDLGF", "length": 684, "header": "tr|A0A8C2M026-1|A0A8C2M026_CRIGR Isoform 1 of Sec1 family domain-containing protein 2 isoform X3 OS=Cricetulus griseus OX=10029 GN=Scfd2 PE=3 SV=1 CANONICAL=A0A8C2M026-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F301-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M026/entry#A0A9J7F301-1", "sequence": { "sequence": "MSSAGVLSFAQQGWEQVLAKVKWSVVYLDAACAESLHWSCGSSRLLEAVKGPACNLREFEPQAIGGGAQQPRAVFVLSCLLKGRTVDTLQDIIRRSHFQYCVVVTAVSHAVHLTANHVPAAAAAELEGQQPVFEQLEEKLCEWMGNVNYTAEVLHVPLLLAPAAPHLAFTPAFATLFPLLPRDVHLLNSARPDKRRLINLSEVDATSLTPELLLHIRCLVSGLSSLCEHLGVREECFAVGALSRVIATDLANYAPAKNRRKTATGRASVVFVDRTLDLTGAVGHHGDNLIEKIISVLPQLPGHTSDVMVNMVELTAVQTMEENQNVIAPGCLAQSNDTSGKALWEALLNTKHKEAVMEVRRHLVEAASRENLPIRMSMGRVTPGQLMSYIQLFKNNLKALTNHCGLLQLGMATVQTLKHPQTAKWDNFLAFERLLLQSLGDSTMAVVLNQLLPMIKSPSQRTSDDYSSEELLILLIYIYSVTGEFVLDKDLREAEDRVKKALAHVFSEESELSPLLQKITGCDSAINLTFPKSQLAVNDIFTSLQEIAGARTLMRQFKSVYVPGNHTHQASYKPLLKQVVEEIFNPEKPDPTDIEHTSSGLTDLLKTGFSMFMKVSRPHPSDHPLLILFVVGGITVSEAKMVKDLVASLKTGTQDC", "length": 656, "header": "tr|A0A9J7F301-1|A0A9J7F301_CRIGR Computationally mapped isoform of Sec1 family domain-containing protein 2 isoform X4 OS=Cricetulus griseus OX=10029 GN=Scfd2 PE=3 SV=1 CANONICAL=A0A8C2M026-1" }, "locus": {} }, { "isoform_ac": "A0A9J7J890-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M026/entry#A0A9J7J890-1", "sequence": { "sequence": "MSSAGVLSFAQQGWEQVLAKVKWSVVYLDAACAESLHWSCGSSRLLEAVKGPACNLREFEPQAIGGGAQQPRAVFVLSCLLKGRTVDTLQDIIRRSHFQYCVVVTAVSHAVHLTANHVPAAAAAELEGQQPVFEQLEEKLCEWMGNVNYTAEVLHVPLLLAPAAPHLAFTPAFATLFPLLPRDVHLLNSARPDKRRLINLSEVDATSLTPELLLHIRCLVSGLSSLCEHLGVREECFAVGALSRVIATDLANYAPAKNRRKTATGRASVVFVDRTLDLTGAVGHHGDNLIEKIISVLPQLPGHTSDVMVNMVELTAVQTMEENQNVIAPGCLAQSNDTSGKALWEALLNTKHKEAVMEVRRHLVEAASRENLPIRMSMGRVTPGQLMSYIQLFKNNLKALTNHCGLLQLGMATVQTLKHPQTAKWDNFLAFERLLLQSLGDSTMAVVLNQLLPMIKSPSQRTSDDYSSEELLILLIYIYSVTGEFVLDKDLREAEDRVKKALAHVFSEESELSPLLQKITVCS", "length": 523, "header": "tr|A0A9J7J890-1|A0A9J7J890_CRIGR Computationally mapped isoform of Sec1 family domain-containing protein 2 isoform X7 OS=Cricetulus griseus OX=10029 GN=Scfd2 PE=4 SV=1 CANONICAL=A0A8C2M026-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KBU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M026/entry#A0A9J7KBU7-1", "sequence": { "sequence": "MSSAGVLSFAQQGWEQVLAKVKWSVVYLDAACAESLHWSCGSSRLLEAVKGPACNLREFEPQAIGGGAQQPRAVFVLSCLLKGRTVDTLQDIIRRSHFQYCVVVTAVSHAVHLTANHVPAAAAAELEGQQPVFEQLEEKLCEWMGNVNYTAEVLHVPLLLAPAAPHLAFTPAFATLFPLLPRDVHLLNSARPDKRRLINLSEVDATSLTPELLLHIRCLVSGLSSLCEHLGVREECFAVGALSRVIATDLANYAPAKNRRKTATGRASVVFVDRTLDLTGRVTPGQLMSYIQLFKNNLKALTNHCGLLQLGMATVQTLKHPQTAKWDNFLAFERLLLQSLGDSTMAVVLNQLLPMIKSPSQRTSDDYSSEELLILLIYIYSVTGEFVLDKDLREAEDRVKKALAHVFSEESELSPLLQKITGCDSAINLTFPKSQLAVNDIFTSLQEIAGARTLMRQFKSVYVPGNHTHQASYKPLLKQVVEEIFNPEKPDPTDIEHTSSGLTDLLKTGFSMFMKVSRPHPSDHPLLILFVVGGITVSEAKMVKDLVASLKTGTQVMVLSTRLLKPLNIPELLFATDRLHPDLGF", "length": 585, "header": "tr|A0A9J7KBU7-1|A0A9J7KBU7_CRIGR Computationally mapped isoform of Sec1 family domain-containing protein 2 isoform X6 OS=Cricetulus griseus OX=10029 GN=Scfd2 PE=3 SV=1 CANONICAL=A0A8C2M026-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 382, "start_aa": "Thr", "end_pos": 382, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr382", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LX22", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LX22" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LX22", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LX22" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755789", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755789", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M026", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M026" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035294562", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294562" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LX94", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LX94" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tldc2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LX94", "locus": {} } ], "crossref": [ { "id": "100755234", "url": "https://www.ncbi.nlm.nih.gov/gene/100755234", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755234", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755234", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HYGLWCD", "url": "https://omabrowser.org/oma/group/HYGLWCD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LX94", "url": "https://www.orthodb.org/?gene=A0A8C2LX94", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23354", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23354", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23354:SF65", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23354:SF65", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07534", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07534", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035294562", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294562", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LX94", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LX94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LX94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LX94-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1B6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1B6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1B6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1B6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKGRRWRYTQLPTQVEDTLSGEEGEKEEEEEEEEAVPVPQEPVEPQLTEASQVLGVSEIKQLSLHLPARVTGHPWSLVFCTSRDGFSLRRLYRQMEGHSGPTLLLLKDQDGQMFGAFSSSAIRLSKGFYGTGETFLFSFSPQLKVFKWTGSNSFFVKGDLDSLMMGSGSGQFGLWLDGDLYHGGSYPCATFNNEVLARQEQFCIEELEAWALS", "length": 213, "header": "tr|A0A8C2LX94-1|A0A8C2LX94_CRIGR Isoform 1 of TLD domain-containing protein 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tldc2 PE=4 SV=1 CANONICAL=A0A8C2LX94-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LX94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LX94/entry#A0A8C2LX94-1", "sequence": { "sequence": "MKGRRWRYTQLPTQVEDTLSGEEGEKEEEEEEEEAVPVPQEPVEPQLTEASQVLGVSEIKQLSLHLPARVTGHPWSLVFCTSRDGFSLRRLYRQMEGHSGPTLLLLKDQDGQMFGAFSSSAIRLSKGFYGTGETFLFSFSPQLKVFKWTGSNSFFVKGDLDSLMMGSGSGQFGLWLDGDLYHGGSYPCATFNNEVLARQEQFCIEELEAWALS", "length": 213, "header": "tr|A0A8C2LX94-1|A0A8C2LX94_CRIGR Isoform 1 of TLD domain-containing protein 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tldc2 PE=4 SV=1 CANONICAL=A0A8C2LX94-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H1B6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LX94/entry#A0A9J7H1B6-1", "sequence": { "sequence": "MKGRRWRYTQLPTQVEDTLSGEEGEKEEEEEEEEAVPVPQEPVEPQLTEASQVLGVSEIKQLSLHLPARVTGHPWSLVFCTSRDGFSLRRLYRQMEGHSGPTLLLLKDQDGQVFKWTGSNSFFVKGDLDSLMMGSGSGQFGLWLDGDLYHGGSYPCATFNNEVLARQEQFCIEELEAWALS", "length": 181, "header": "tr|A0A9J7H1B6-1|A0A9J7H1B6_CRIGR Computationally mapped isoform of TLD domain-containing protein 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Tldc2 PE=4 SV=1 CANONICAL=A0A8C2LX94-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LX94", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LX94" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LX94", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LX94" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755234", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755234", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BJT4-1", "protein_name": "TBC/LysM-associated domain containing 2", "gene_name": "TLDC2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKGLRWRYTRLPSQAENALSEEEGEEEEDEGDTVPAPAPAPEDPVEPQLAEASQVLGASEIRQLSLHLPPRVTGHSWSLAFCTSRNGFSLRSLYRQMEGHNGPVLLVLRDHDGQMFGAFSSSAIRLSKNFYGTGETFLFTFSPQLKVFKWTGSNSFFVKGDLDLLMIGCGSGHFGLWLDGDLYHGGSHPCATFNNEVLARQEQFCIKELEAWVLS", "length": 215 }, "evidence": [ { "id": "A0A8C2LX94", "url": "https://omabrowser.org/oma/group/A0A8C2LX94/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0PJX2-1", "protein_name": "TLD domain-containing protein 2", "gene_name": "TLDC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRGLRWRYTRLPSQVEDTLSGEEGNEEEEEEEAAPDPAAAPEDPTVPQLTEASQVLSASEIRQLSFHFPPRVTGHPWSLVFCTSRDGFSLQSLYRRMEGCSGPVLLVLRDQDGQIFGAFSSSAIRLSKGFYGTGETFLFSFSPQLKVFKWTGSNSFFVKGDLDSLMMGSGSGRFGLWLDGDLFRGGSSPCPTFNNEVLARQEQFCIQELEAWLLS", "length": 215 }, "evidence": [ { "id": "A0A8C2LX94", "url": "https://omabrowser.org/oma/group/A0A8C2LX94/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A2ACG1-1", "protein_name": "TLD domain-containing protein 2", "gene_name": "Tldc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDTLSGEEGEEEEEEEPAPAPAPQDPVEPQLTEASQVLGASEIKQLSLHLPPRVTGHPWSLVFCTSRDGFSLRRLYRQMEGHSGPVLLLLRDQDGQMFGAFSSSAIRLSKGFYGTGETFLFSFSPQLKVFKWTGHNSFFVKGDLDSLMMGSGSGQFGLWLDGDLYHGGSYPCATFNNEVLARREQFCIKELEAWVLS", "length": 198 }, "evidence": [ { "id": "A0A8C2LX94", "url": "https://omabrowser.org/oma/group/A0A8C2LX94/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZQ38-1", "protein_name": "TBC/LysM-associated domain containing 2", "gene_name": "Tldc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKGRQWRYTQLPTEMEDTLSGEEGEEEEEEEPAPAPQDPVEPQLTEASQVLGASEIKQLSLHLPPRVTGHPWNLIFCTSRDGFSLQRLYRQMEGHSGPVLLLLRDQDGQMFGAFSSSALRLSKGFYGTGETFLFSFSPQLKVFKWTGHNSFFVKGDLDSLMMGSGSGQFGLWLDGDLYHGGSYPCATFNNEVLARREQFCIRELEAWALS", "length": 210 }, "evidence": [ { "id": "A0A8C2LX94", "url": "https://omabrowser.org/oma/group/A0A8C2LX94/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": 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"GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LX94", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LX94" } ], "pmid": "" }, { "name": "negative regulation of cellular response to oxidative stress", "id": "GO:1900408", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1900408", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LX94", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LX94" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LX94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LX94" }, { "id": "PS51886", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51886" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LXH7-1", "uniprot_ac": "A0A8C2LXH7", "uniprot_id": "A0A8C2LXH7_CRIGR", "mass": { "chemical_mass": 59205.0, "monoisotopic_mass": 59205.0 }, "refseq": { "ac": "XP_027281014", "name": "protein INSYN2B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281014" }, "gene_names": [ { "name": "Insyn2b", "type": "recommended", "evidence": [ { "id": "A0A8C2LXH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXH7" } ] }, { "name": "Insyn2b", "type": "synonym", "evidence": [ { "id": "XP_027281014", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281014" } ] } ], "protein_names": [ { "name": "Protein INSYN2B", "type": "synonym", "evidence": [ { "id": "A0A8C2LXH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXH7/entry#names_and_taxonomy" } ] }, { "name": "protein INSYN2B", "type": "synonym", "evidence": [ { "id": "XP_027281014", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281014" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027281014", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281014" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LXH7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXH7" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Insyn2b", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXH7", "locus": {} } ], "crossref": [ { "id": "100756585", "url": "https://www.ncbi.nlm.nih.gov/gene/100756585", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100756585", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100756585", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LXH7", "url": "https://www.orthodb.org/?gene=A0A8C2LXH7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28682", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28682", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28682:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28682:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15265", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15265", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027281014", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027281014", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LXH7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LXH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXH7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQQSMKVRPVLLKRSSLESVELVKQPHHRRSKSQQVRFKEDGNTKSPTGVTEVDTQTPEDPSLMGKTQASQHHHPTTYSLSFPRSHKAGGFRSISIQTSPSLRKHFPVFKRKKLTTSKSLVEMPTASPSAIQVNGNLSEQDVVSSDLAFLRLAQHLEDGPRRLKMPHPFLPRMSKVQSNGPVSFCLESGTWRSSEKATAAIQVPDDICHSPTWETREPTFSTESSAKESNSIPTLVTMCPGDGQRVPISDPERFPSCLNANGSANNTPGAGKLTPELLLPKDNPENKDIGLLSSQSKKMCVPSPSRTHSSSETGSHSQLAHLGRVSDCPASSDNHQDLESLKSSSASKSTPVCWEHVAKLPSQSDIPDLQTGLGSEHLPSSLPRHEYKPQSSRELSGSNHSHLAQGELCDLQGRLQSVEESLHSNQEKIKVLLNVIQDLEKARALTEGRNFYRTGQDLNNCSTCQNTACIIYSVEYDFRQQEGRFHEVLQNLEEAEPAEEAPSPPKSPAEAQVPEKQDVRRKSKKVKKKCFWWI", "length": 535, "header": "tr|A0A8C2LXH7-1|A0A8C2LXH7_CRIGR Isoform 1 of Protein INSYN2B OS=Cricetulus griseus OX=10029 GN=Insyn2b PE=4 SV=1 CANONICAL=A0A8C2LXH7-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LXH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXH7/entry#A0A8C2LXH7-1", "sequence": { "sequence": "MAQQSMKVRPVLLKRSSLESVELVKQPHHRRSKSQQVRFKEDGNTKSPTGVTEVDTQTPEDPSLMGKTQASQHHHPTTYSLSFPRSHKAGGFRSISIQTSPSLRKHFPVFKRKKLTTSKSLVEMPTASPSAIQVNGNLSEQDVVSSDLAFLRLAQHLEDGPRRLKMPHPFLPRMSKVQSNGPVSFCLESGTWRSSEKATAAIQVPDDICHSPTWETREPTFSTESSAKESNSIPTLVTMCPGDGQRVPISDPERFPSCLNANGSANNTPGAGKLTPELLLPKDNPENKDIGLLSSQSKKMCVPSPSRTHSSSETGSHSQLAHLGRVSDCPASSDNHQDLESLKSSSASKSTPVCWEHVAKLPSQSDIPDLQTGLGSEHLPSSLPRHEYKPQSSRELSGSNHSHLAQGELCDLQGRLQSVEESLHSNQEKIKVLLNVIQDLEKARALTEGRNFYRTGQDLNNCSTCQNTACIIYSVEYDFRQQEGRFHEVLQNLEEAEPAEEAPSPPKSPAEAQVPEKQDVRRKSKKVKKKCFWWI", "length": 535, "header": "tr|A0A8C2LXH7-1|A0A8C2LXH7_CRIGR Isoform 1 of Protein INSYN2B OS=Cricetulus griseus OX=10029 GN=Insyn2b PE=4 SV=1 CANONICAL=A0A8C2LXH7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035294796", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294796" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LXJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXJ2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100765211", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXJ2", "locus": {} } ], "crossref": [ { "id": "100765211", "url": "https://www.ncbi.nlm.nih.gov/gene/100765211", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000077", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000077", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765211", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765211", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PWIRMKT", "url": "https://omabrowser.org/oma/group/PWIRMKT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LXJ2", "url": "https://www.orthodb.org/?gene=A0A8C2LXJ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19970", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19970", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19970:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19970:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00832", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00832", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035294796", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035294796", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LXJ2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LXJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSHKTCRIKGFLAKKQKQNRPIPQWIQMKTGNKIRYNSKRRHWRRTKLGL", "length": 51, "header": "tr|A0A8C2LXJ2-1|A0A8C2LXJ2_CRIGR Isoform 1 of 60S ribosomal protein L39-like OS=Cricetulus griseus OX=10029 GN=LOC100765211 PE=3 SV=1 CANONICAL=A0A8C2LXJ2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LXJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXJ2/entry#A0A8C2LXJ2-1", "sequence": { "sequence": "MSSHKTCRIKGFLAKKQKQNRPIPQWIQMKTGNKIRYNSKRRHWRRTKLGL", "length": 51, "header": "tr|A0A8C2LXJ2-1|A0A8C2LXJ2_CRIGR Isoform 1 of 60S ribosomal protein L39-like OS=Cricetulus griseus OX=10029 GN=LOC100765211 PE=3 SV=1 CANONICAL=A0A8C2LXJ2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"yes" } }, { "uniprot_canonical_ac": "A0A8C2LXQ4-1", "uniprot_ac": "A0A8C2LXQ4", "uniprot_id": "A0A8C2LXQ4_CRIGR", "mass": { "chemical_mass": 13598.0, "monoisotopic_mass": 13598.0 }, "refseq": { "ac": "XP_003502895", "name": "protein yippee-like 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502895" }, "gene_names": [ { "name": "Ypel1", "type": "recommended", "evidence": [ { "id": "A0A8C2LXQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXQ4" } ] }, { "name": "YPEL", "type": "synonym", "evidence": [ { "id": "A0A8C2LXQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXQ4" } ] }, { "name": "Ypel1", "type": "synonym", "evidence": [ { "id": "XP_003502895", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502895" } ] } ], "protein_names": [ { "name": "Protein yippee-like", "type": "recommended", "evidence": [ { "id": "A0A8C2LXQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXQ4/entry#names_and_taxonomy" } ] }, { "name": "protein yippee-like 1", "type": "synonym", "evidence": [ { "id": "XP_003502895", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502895" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613919.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003502895", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502895" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LXQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXQ4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Ypel1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXQ4", "locus": {} } ], "crossref": [ { "id": "100759808", "url": "https://www.ncbi.nlm.nih.gov/gene/100759808", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759808", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759808", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HLAFKGH", "url": "https://omabrowser.org/oma/group/HLAFKGH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LXQ4", "url": "https://www.orthodb.org/?gene=A0A8C2LXQ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13848", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13848", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003502895", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003502895", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LXQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LXQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVKMTKSKTFQAYLPHCHRTYSCIHCRAHLANHDELISKSFQGSQGRAYLFNSVVNVGCGPAEERVLLTGLHAVADIYCENCKTTLGWKYEHAFESSQKYKEGKFIIELAHMIKDNGWE", "length": 119, "header": "tr|A0A8C2LXQ4-1|A0A8C2LXQ4_CRIGR Isoform 1 of Protein yippee-like OS=Cricetulus griseus OX=10029 GN=Ypel1 PE=3 SV=1 CANONICAL=A0A8C2LXQ4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LXQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXQ4/entry#A0A8C2LXQ4-1", "sequence": { "sequence": "MVKMTKSKTFQAYLPHCHRTYSCIHCRAHLANHDELISKSFQGSQGRAYLFNSVVNVGCGPAEERVLLTGLHAVADIYCENCKTTLGWKYEHAFESSQKYKEGKFIIELAHMIKDNGWE", "length": 119, "header": "tr|A0A8C2LXQ4-1|A0A8C2LXQ4_CRIGR Isoform 1 of Protein yippee-like OS=Cricetulus griseus OX=10029 GN=Ypel1 PE=3 SV=1 CANONICAL=A0A8C2LXQ4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"Q9ESC7-1", "protein_name": "Protein yippee-like 1", "gene_name": "Ypel1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVKMTKSKTFQAYLPHCHRTYSCIHCRAHLANHDELISKSFQGSQGRAYLFNSVVNVGCGPAEERVLLTGLHAVADIYCENCKTTLGWKYEHAFESSQKYKEGKFIIELAHMIKDNGW", "length": 118 }, "evidence": [ { "id": "A0A8C2LXQ4", "url": "https://omabrowser.org/oma/group/A0A8C2LXQ4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LXQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXQ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": 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This gene is part of an endogenous retrovirus provirus that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product plays a major role in placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. [provided by RefSeq, Apr 2015]. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292147" }, "gene_names": [ { "name": "Synb", "type": "recommended", "evidence": [ { "id": "A0A8C2LXT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXT2" } ] }, { "name": "Synb", "type": "synonym", "evidence": [ { "id": "NP_001292147", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292147" } ] } ], "protein_names": [ { "name": "Syncytin b precursor", "type": "synonym", "evidence": [ { "id": "A0A8C2LXT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXT2/entry#names_and_taxonomy" } ] }, { "name": "syncytin b precursor", "type": "synonym", "evidence": [ { "id": "NP_001292147", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292147" } ] } ], "function": [ { "annotation": "Many different endogenous retrovirus families are expressed in normal placental tissue at high levels, suggesting that endogenous retroviruses are functionally important in reproduction. This gene is part of an endogenous retrovirus provirus that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product plays a major role in placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. [provided by RefSeq, Apr 2015]. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001292147", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292147" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LXT2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXT2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Synb", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXT2", "locus": {} } ], "crossref": [ { "id": "cd09851", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09851", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "105349233", "url": "https://www.ncbi.nlm.nih.gov/gene/105349233", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018154", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018154", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:105349233", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:105349233", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TRFCQGR", "url": "https://omabrowser.org/oma/group/TRFCQGR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LXT2", "url": "https://www.orthodb.org/?gene=A0A8C2LXT2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10424", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10424", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10424:SF83", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10424:SF83", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00429", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00429", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001292147", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001292147", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LXT2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LXT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXT2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTCLWVLYFALFPYSLSYPESWMPLINLTHHILREANSSLFSNCWVCLSTQTQRSLAVPAPLSTWTDSPMKLHLTYSVKPFPGSYPITNIERRLQVFHPLTASYSFHNSDRRAIAFLQLVSSTGIFPIITRLTSVIYPDMDHFFETAQRPLWGPLFTETLLKSQAPLCISRFFKVSAYATFVGALPASLCNYTLHMEPSTSYENLDLSTIHPFKQAMKRPDAKWKNPLRFSGPPSLVSTKPSYYPCPTDVKHCHTSPATPWMRCPLSPSGTCYNLTLYESDNLTHPVTVSVNPTYFKIKLQGHRDPYPYFHYQPLTGAALSGQYSVWENEVTIHENWDVTSNIFSHLLTFSYSFCLNSSGVFFLCGTSTYVCLPANWSGVCTLVFQYPDIELLPNNQTVLVPLFASVLSSASASRPKRSPHLLPFLAGLGISSALGTGIAGLASSMFYFQRLSKALSDTLDEIAASITTLQNQIDSLAGVVLQNRRALDLITAEKGGTCLFLQEECCFYVNQSGIVRDAARKLRERASELGQHSDSWGQWPDPGYWLPWLSPFLGPLLFIFFLLTFGSCLINCLTHCVSQRLGSFVQDTTKRHMDSILQNFQYKRLPQEPLDEVTTPM", "length": 618, "header": "tr|A0A8C2LXT2-1|A0A8C2LXT2_CRIGR Isoform 1 of Syncytin b precursor OS=Cricetulus griseus OX=10029 GN=Synb PE=4 SV=1 CANONICAL=A0A8C2LXT2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LXT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXT2/entry#A0A8C2LXT2-1", "sequence": { "sequence": "MTCLWVLYFALFPYSLSYPESWMPLINLTHHILREANSSLFSNCWVCLSTQTQRSLAVPAPLSTWTDSPMKLHLTYSVKPFPGSYPITNIERRLQVFHPLTASYSFHNSDRRAIAFLQLVSSTGIFPIITRLTSVIYPDMDHFFETAQRPLWGPLFTETLLKSQAPLCISRFFKVSAYATFVGALPASLCNYTLHMEPSTSYENLDLSTIHPFKQAMKRPDAKWKNPLRFSGPPSLVSTKPSYYPCPTDVKHCHTSPATPWMRCPLSPSGTCYNLTLYESDNLTHPVTVSVNPTYFKIKLQGHRDPYPYFHYQPLTGAALSGQYSVWENEVTIHENWDVTSNIFSHLLTFSYSFCLNSSGVFFLCGTSTYVCLPANWSGVCTLVFQYPDIELLPNNQTVLVPLFASVLSSASASRPKRSPHLLPFLAGLGISSALGTGIAGLASSMFYFQRLSKALSDTLDEIAASITTLQNQIDSLAGVVLQNRRALDLITAEKGGTCLFLQEECCFYVNQSGIVRDAARKLRERASELGQHSDSWGQWPDPGYWLPWLSPFLGPLLFIFFLLTFGSCLINCLTHCVSQRLGSFVQDTTKRHMDSILQNFQYKRLPQEPLDEVTTPM", "length": 618, "header": "tr|A0A8C2LXT2-1|A0A8C2LXT2_CRIGR Isoform 1 of Syncytin b precursor OS=Cricetulus griseus OX=10029 GN=Synb PE=4 SV=1 CANONICAL=A0A8C2LXT2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Syncytin-A and syncytin-B, two fusogenic placenta-specific murine envelope genes of retroviral origin conserved in Muridae.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2005", "authors": "Dupressoir A, Marceau G, Vernochet C, Benit L, Kanellopoulos C, Sapin V, Heidmann T", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LXT2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXT2" } ], "reference": [ { "type": "PubMed", "id": "15644441", "url": "https://glygen.org/publication/PubMed/15644441" } ] }, { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LXT2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXT2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LXT2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXT2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:105349233", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:105349233", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A443-1", "protein_name": "Syncytin b", "gene_name": "Synb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTHLWVLCFVLFPSSLSYPESWMPLINLTHHILRDANSSLFPNCWVCLSTQTQRSLAVPAPLSTWTDTPMKLHLTYSVKAFPGSFPISDLERRLRLFHPLIASYPFHNPERRAITFLQLVSSTGIFRIITRITSVIYPEKDRFFESAQRPLWGPLFTETVLRSQAPLCISRFFKVSAYATFVGNLSASLCNYTLRISPSTSHENLDLSITHPFKQAMKRPNAKWKNPLRFSGPPSLIFSKPSYHPCPADKYCHTSPATPWMRCPHAPSSTCYNLTLFESDNLTHPVTMSVDSTHFKAKLQGRRDPYPLSHYQPIPGAALSGQYSVWENEITIQENWGVTSNIFSHLLSFSYIFCLNSSGVFFLCGTSTYVCLPANWSGVCTLVFQYPDIELLPNNQTVPVPLFASVLSSASVLRPKRSPHLLPFLAGLGISSALGTGIAGLASSTLYFQRLSKALSETLEEIAASITTLQNQIDSLAGVVLQNRRALDLITAEKGGTCLFLQEECCFYVNQSGIVRDAARKLRERASELSQHSDSWGQWPDPGRWLPWLTPFLGPLLFIFFLLTFGSCLLNCLTRFVSQRLGSFVQDTAKMQVDSILQNFQYKKLPQDSQDEDTIPM", "length": 617 }, "evidence": [ { "id": "A0A8C2LXT2", "url": "https://omabrowser.org/oma/group/A0A8C2LXT2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P60508-1", "protein_name": "Syncytin-2", "gene_name": "ERVFRD-1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLLLLVLILTPSLAAYRHPDFPLLEKAQQLLQSTGSPYSTNCWLCTSSSTETPGTAYPASPREWTSIEAELHISYRWDPNLKGLMRPANSLLSTVKQDFPDIRQKPPIFGPIFTNINLMGIAPICVMAKRKNGTNVGTLPSTVCNVTFTVDSNQQTYQTYTHNQFRHQPRFPKPPNITFPQGTLLDKSSRFCQGRPSSCSTRNFWFRPADYNQCLQISNLSSTAEWVLLDQTRNSLFWENKTKGANQSQTPCVQVLAGMTIATSYLGISAVSEFFGTSLTPLFHFHISTCLKTQGAFYICGQSIHQCLPSNWTGTCTIGYVTPDIFIAPGNLSLPIPIYGNSPLPRVRRAIHFIPLLAGLGILAGTGTGIAGITKASLTYSQLSKEIANNIDTMAKALTTMQEQIDSLAAVVLQNRRGLDMLTAAQGGICLALDEKCCFWVNQSGKVQDNIRQLLNQASSLRERATQGWLNWEGTWKWFSWVLPLTGPLVSLLLLLLFGPCLLNLITQFVSSRLQAIKLQTNLSAGRHPRNIQESPF", "length": 538 }, "evidence": [ { "id": "A0A8C2LXT2", "url": "https://omabrowser.org/oma/group/A0A8C2LXT2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BI41-1", "protein_name": "Syncytin-B", "gene_name": "Synb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGFWVLCFVLFPSSLSYPESWMPLVNLTHHILRDTNSSLFSNCWVCLSTQTQRSLAVPAPLSIWTDTPMKLHLTYSVRPFSGSFSISDIERRLRLFRPLTASYSFHNPDRRAIAFLQLVSSTGIFRIITRITSVIYPHKDRFFESAQRPLWGPLFTETVLRSQAPLCISRFFKVSAYATFVGNLSASLCNYTMHISPSTSHENLDLSTTHTFKQAMKRPDAKWKNPLRFSGPPSLIFSKPAYYPCPTDIKHCHTSPATPWMHCPQAPFGTCYNLTLFEPDNSTHPVTMSVNPTHFKVKLQGHRDPYPLSHYQPLTGAALSGQYSVWENEITVQENWDITSNIFSHLLSFSYAFCLNSSGVFFLCGTSTYICLPANWSGVCTLVFQYPDIELLPNNQTVPVPLFASVLSSDSVLRPKRSPHLFPFLAGLGISSALGTGIAGLATSTLYFQQLSKVLSETLEEIAASITTLQNQIDSLAGVVLQNRRALDLITAEKGGTCLFLQEECCFYVNQSGIVRDAARKLQERASELGQHSDSWGQWPDLGRWLPWLTPFLGPLLFLFFLLTFGSCLLNCLTRFVSQRLGSFVQDTAKRHVDSILQNFQYKKLPQDSPDEDTIPT", "length": 618 }, "evidence": [ { "id": "A0A8C2LXT2", "url": "https://omabrowser.org/oma/group/A0A8C2LXT2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "syncytium formation by plasma membrane fusion", "id": "GO:0000768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000768", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LXT2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXT2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LXT2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXT2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" }, { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 357, "end_pos": 359, "annotation": "n_glycosylation_sequon" }, { "start_pos": 376, "end_pos": 378, "annotation": "n_glycosylation_sequon" }, { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" }, { "start_pos": 396, "end_pos": 398, "annotation": "n_glycosylation_sequon" }, { "start_pos": 511, "end_pos": 513, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 191, "end_pos": 193 }, { "start_pos": 274, "end_pos": 276 }, { "start_pos": 27, "end_pos": 29 }, { "start_pos": 282, "end_pos": 284 }, { "start_pos": 357, "end_pos": 359 }, { "start_pos": 376, "end_pos": 378 }, { "start_pos": 37, "end_pos": 39 }, { "start_pos": 396, "end_pos": 398 }, { "start_pos": 511, "end_pos": 513 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LXT3-1", "uniprot_ac": "A0A8C2LXT3", "uniprot_id": "A0A8C2LXT3_CRIGR", "mass": { "chemical_mass": 28226.0, "monoisotopic_mass": 28226.0 }, "refseq": { "ac": "XP_027267187", "name": "proline-rich protein 23A3 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267187" }, "gene_names": [ { "name": "LOC100761608", "type": "recommended", "evidence": [ { "id": "A0A8C2LXT3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXT3" } ] }, { "name": "LOC100761608", "type": "synonym", "evidence": [ { "id": "XP_027267187", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027267187" } ] } ], "protein_names": [ { "name": "Proline-rich protein 23A3 isoform X2", 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This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. 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This record is derived from a genomic sequence (NW_003615616.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035292922", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035292922" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LXY2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXY2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Cldnd2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXY2", "locus": {} } ], "crossref": [ { "id": "100752776", "url": "https://www.ncbi.nlm.nih.gov/gene/100752776", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004031", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004031", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050579", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050579", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752776", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752776", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NDVFFSW", "url": "https://omabrowser.org/oma/group/NDVFFSW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LXY2", "url": "https://www.orthodb.org/?gene=A0A8C2LXY2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10671", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10671", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10671:SF30", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10671:SF30", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00822", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00822", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035292922", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035292922", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LXY2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LXY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXY2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGVKRSLQTGGNLLNLLTSILTVLSTSTNYWIRQSGGHSGLWQECTHGICSNIPCQNTLAVTAACMVLSATFSIISLGMGMRIWYQEREPLRSQNTIVLLFLSGLLLMIALTGYTAKNAWKQEVFFSWSYFFGWLALPFSFLAGFCFLLADMIMQSTEAISGFPVCL", "length": 167, "header": "tr|A0A8C2LXY2-1|A0A8C2LXY2_CRIGR Isoform 1 of Claudin domain-containing protein 2 OS=Cricetulus griseus OX=10029 GN=Cldnd2 PE=3 SV=1 CANONICAL=A0A8C2LXY2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LXY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXY2/entry#A0A8C2LXY2-1", "sequence": { "sequence": "MGVKRSLQTGGNLLNLLTSILTVLSTSTNYWIRQSGGHSGLWQECTHGICSNIPCQNTLAVTAACMVLSATFSIISLGMGMRIWYQEREPLRSQNTIVLLFLSGLLLMIALTGYTAKNAWKQEVFFSWSYFFGWLALPFSFLAGFCFLLADMIMQSTEAISGFPVCL", "length": 167, "header": "tr|A0A8C2LXY2-1|A0A8C2LXY2_CRIGR Isoform 1 of Claudin domain-containing protein 2 OS=Cricetulus griseus OX=10029 GN=Cldnd2 PE=3 SV=1 CANONICAL=A0A8C2LXY2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LXY2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXY2" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LXY2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXY2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100752776", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752776", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2RCV6-1", "protein_name": "Claudin domain-containing protein 2", "gene_name": "CLDND2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGVKRSLQTGGTLLGFLANILTVLSTASNYWIRYSGGHSGLWQECKEGICSNIPCQTMLTVTGACMVLAVGCSIVGLMMGLRIRCHEGDLRGKNTSAIFFLGGLLLLIALTGYTAKNAWKDDVFFSWSYFSGWLALPFSILAGFCFLLADMILQSTDAISGFPVCL", "length": 166 }, "evidence": [ { "id": "A0A8C2LXY2", "url": "https://omabrowser.org/oma/group/A0A8C2LXY2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZQB5-1", "protein_name": "Claudin domain-containing protein 2", "gene_name": "Cldnd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGVKKSLQTGGNLLNLLSSVLTVLSTTTSYWIRQQGGHSGLWQECTHGVCSNMPCQNTLAVTTACMVLAAAFSIVALGMGIRIQCQEAESLRSQNTIVLLFLSGLLLLIALTVYTAKNAWKPEVFFSWSYFFGWLALPFSFIAGFCFLLADMIMQSTEAISGFPVCL", "length": 167 }, "evidence": [ { "id": "A0A8C2LXY2", "url": "https://omabrowser.org/oma/group/A0A8C2LXY2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BNM0-1", "protein_name": "Claudin domain-containing protein 2", "gene_name": "CLDND2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGVKRSLQSGGTMLGFLANSFIVLSTASNYWIRYSGGHSGLWQECNEGICSNIPCDSTLAVTGACMVLAAGCGIMGLVMGLRLLCSEGYSRGQTTCAVFFISGLLLLIALTVYTVKNAWKDDVFYSWSYFLGWLALPFSILAGFCFLLADMIMQSTDAISGFPVCL", "length": 166 }, "evidence": [ { "id": "A0A8C2LXY2", "url": "https://omabrowser.org/oma/group/A0A8C2LXY2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8NHS1-1", "protein_name": "Claudin domain-containing protein 2", "gene_name": "CLDND2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGVKRSLQSGGILLSLVANVLMVLSTATNYWTRQQEGHSGLWQECNHGICSSIPCQTTLAVTVACMVLAVGVGVVGMVMGLRIRCDEGESLRGQTTSAFLFLGGLLLLTALIGYTVKNAWKNNVFFSWSYFSGWLALPFSILAGFCFLLADMIMQSTDAISGFPVCL", "length": 167 }, "evidence": [ { "id": "A0A8C2LXY2", "url": "https://omabrowser.org/oma/group/A0A8C2LXY2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D9H2-1", "protein_name": "Claudin domain-containing protein 2", "gene_name": "Cldnd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGVKKSLQTGGNLLNLLSSILTVLSTTTNYWTRQQGGHSGLWQECTHGKCSNIPCQNTVAVSAACMVLAATFSIVALGIGIRIQCREAESRRSQNTIVLLFLSGLLLLIALAVYTSKNAWKPEVFFSWSYFFGWLALPFLFIAGFCFLLADMILQSTEAISGFPVCL", "length": 167 }, "evidence": [ { "id": "A0A8C2LXY2", "url": "https://omabrowser.org/oma/group/A0A8C2LXY2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LXY2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXY2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LXZ1-1", "uniprot_ac": "A0A8C2LXZ1", "uniprot_id": "A0A8C2LXZ1_CRIGR", "mass": { "chemical_mass": 87954.0, "monoisotopic_mass": 87954.0 }, "refseq": { "ac": "XP_027253885", "name": "protocadherin beta-16", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253885" }, "gene_names": [ { "name": "LOC103162546", "type": "recommended", "evidence": [ { "id": "A0A8C2LXZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXZ1" } ] }, { "name": "LOC103162546", "type": "synonym", "evidence": [ { "id": "XP_027253885", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253885" } ] } ], "protein_names": [ { "name": "Protocadherin beta-16", "type": "synonym", "evidence": [ { "id": "A0A8C2LXZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXZ1/entry#names_and_taxonomy" } ] }, { "name": "protocadherin beta-16", "type": "synonym", "evidence": [ { "id": "XP_027253885", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253885" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027253885", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253885" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LXZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXZ1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC103162546", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXZ1", "locus": {} } ], "crossref": [ { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "103162546", "url": "https://www.ncbi.nlm.nih.gov/gene/103162546", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010221", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010221", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050174", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050174", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:103162546", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103162546", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LXZ1", "url": "https://www.orthodb.org/?gene=A0A8C2LXZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028:SF71", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028:SF71", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16492", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16492", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027253885", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253885", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LXZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LXZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LXZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "METAWMHKPRQRQVLIFFVLLSVSEAGTELGPYSIEEEMKRGSFVANLGKDLGVELEKISTRRARIISQENKEHLQLNVQSGDLLINEKLDREELCGSIEPCVLHFQVLMENPLEVFQAELRVKDINDHSPVFSEKEMTLRIPENSPLGSTFPLNNALDSDVEINNIQSYKVSSNSHFLVVTHNRSDGRKYPELVLEKELDREEAPKLRLTLTAWDGGSPPRSGMAWVLIEVVDINDNAPEFQQPTYQVQIPENRPTGSLVVTVSANDLDGGDNGKILYALSQPSEDISKTLEVNPVTGEIRLRRELDFETIPSYEVDIKATDGGGLSGKCTLLLQVVDVNDNPPEVILSALTSQVPENSPDEVVAVFSVRDPDSGENGKVISSIQEDLPFLLKPSGKNFYTLITKRALDREEREQYTIIITVTDLGTPRLTTQHTITVQVSDVNDNAPAFTQTSYTLFVQENNSPALHIGTISATDSDSGSNAHITYSLLPTHDPQLALSSLISINADNGQLFALRALDYEALQTFEFRVGATDQGSPALSSQALVRVLVLDANDNAPFVLYPLQNASAPFTELLPRAAEPGYLVTKVVAVDRDSGQNAWLSFQLLKATEPGLFTVWAHNGEVRTSRQLSERDAPKHRLLLLVKDNGDPPRSASVTLQVLVVDGFSQPYLPLPEVARDPAQEEDELTLYLVIALASVSSLFLLFVLLFVGVRLCRRARASSLGGCSVPEGHFPGHLVDVSGAGTLSQSYQYEVCLMGDSSGSSDLKFLQPVLPSSLPQCSGKEIVENSTLQNSLGFNHY", "length": 800, "header": "tr|A0A8C2LXZ1-1|A0A8C2LXZ1_CRIGR Isoform 1 of Protocadherin beta-16 OS=Cricetulus griseus OX=10029 GN=LOC103162546 PE=4 SV=1 CANONICAL=A0A8C2LXZ1-1" }, "isoforms": [ { 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003506407", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506407" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LY61", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY61" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Mrpl42", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY61", "locus": {} } ], "crossref": [ { "id": "100752233", "url": "https://www.ncbi.nlm.nih.gov/gene/100752233", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019346", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019346", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100752233", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100752233", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LY61", "url": "https://www.orthodb.org/?gene=A0A8C2LY61", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13450", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13450", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13450:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13450:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10210", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10210", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003506407", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003506407", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LY61", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LY61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY61-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F897", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F897", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7F897-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7F897-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRIMATVVKWVTSNRTIWKRLFPIQNGALSSACRKSTYSSLPDDYNCKVELALTSDGRTIVCYHPSVDIPYEHTKPIPQPDILHNNEETHEQVLKAKLGIKSDQLEQGPMIEQLSKVFFTTKHRWYPHGQYHRRRKKLNPPKDR", "length": 144, "header": "tr|A0A8C2LY61-1|A0A8C2LY61_CRIGR Isoform 1 of Large ribosomal subunit protein mL42 OS=Cricetulus griseus OX=10029 GN=Mrpl42 PE=3 SV=1 CANONICAL=A0A8C2LY61-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LY61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY61/entry#A0A8C2LY61-1", "sequence": { "sequence": "MRIMATVVKWVTSNRTIWKRLFPIQNGALSSACRKSTYSSLPDDYNCKVELALTSDGRTIVCYHPSVDIPYEHTKPIPQPDILHNNEETHEQVLKAKLGIKSDQLEQGPMIEQLSKVFFTTKHRWYPHGQYHRRRKKLNPPKDR", "length": 144, "header": "tr|A0A8C2LY61-1|A0A8C2LY61_CRIGR Isoform 1 of Large ribosomal subunit protein mL42 OS=Cricetulus griseus OX=10029 GN=Mrpl42 PE=3 SV=1 CANONICAL=A0A8C2LY61-1" }, "locus": {} }, { "isoform_ac": "A0A9J7F897-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LY61/entry#A0A9J7F897-1", "sequence": { "sequence": "MRIMATVVKWVTSNRTIWKRLFPIQNGALSSACRKSTYSSLPDDYNCKVELALTSDGRTIVCYHPSVDIPYEHTKVSQTS", "length": 80, "header": "tr|A0A9J7F897-1|A0A9J7F897_CRIGR Computationally mapped isoform of Large ribosomal subunit protein mL42 OS=Cricetulus griseus OX=10029 GN=Mrpl42 PE=3 SV=1 CANONICAL=A0A8C2LY61-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027253614", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253614" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LYD5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYD5" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100774912", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYD5", "locus": {} } ], "crossref": [ { "id": "100774912", "url": "https://www.ncbi.nlm.nih.gov/gene/100774912", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005026", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005026", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100774912", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100774912", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LYD5", "url": "https://www.orthodb.org/?gene=A0A8C2LYD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12353", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12353", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12353:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12353:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03359", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03359", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027253614", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027253614", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LYD5", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LYD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYD5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKGLSGSRSHHHGITCESACDSLSHHSDHKPYLLSPVDHHPADHPYYTQRNSFQAECVGPFSDPLASSTFPRRHYTSQQELKDEGALVPRTLATKANRIPANLLDQFERQLPLSRDGYHTLQYKRTAVEHRSDSPGRIRHLVHSVQKLFTKSHSLEGPSKGSVNGGKASPDESQTVRYGKRSKSKERRSESKARSSASNASPTSPSWWSSDDNLDGDMCLYHTPSGVMTMGRCPDRSASQYFMEAYNTISEQAVKASRSNNDIKCSTCANLPVTLDAPLLKKSAWSSTLTVSRAREVYQKASVNMDQAMVKSEACQQERSCQYLQVPQDEWTGYTPRGKDDEIPCRRMRSGSYIKAMADEDSGDSDTSPKPSPKVAARRESYLRATQPSLTELTTLKISNEHSPKLQIRSHSYLRAVSEVSINRSLDSLDPAGLLTSPKFRSRNESYMRAMSTISQVSEMEVNGQFESVCESVFSELESQAVEALDLPMPGCFRMRSHSYVRAIEKGCSQDDECVSLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMDGQGQRGDMISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNSAAVTTTTTIATVTTEDRKKDFKKNRCLSIGIQVDDAEEPEKTGENKAPSKFQSVGVQVEEEKCFRRFTRSNSVTTAVQADLDFHDNLENSLESIEDNSCPGPMARQFSRDASTSTVSIQGSGNHYHACAADDDFDTDFDPSILPPPDPWIDSITEDPLEAVQRSVCHRDGHWFLKLLQAERDRMEGWCQQMEREERENNLPEDILGKIRTAVGSAQLLMAQKFYQFRELCEENLNPNAHPRPTSQDLAGFWDMLQLSIENISMKFDELHQLKANNWKQMDPLDKKERRAPPPVPKKPAKGPAPLIRERSLESSQRQEARKRLMAAKRAASVRQNSATESAESIEIYIPEAQTRL", "length": 982, "header": "tr|A0A8C2LYD5-1|A0A8C2LYD5_CRIGR Isoform 1 of Disks large-associated protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100774912 PE=3 SV=1 CANONICAL=A0A8C2LYD5-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LYD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYD5/entry#A0A8C2LYD5-1", "sequence": { "sequence": "MKGLSGSRSHHHGITCESACDSLSHHSDHKPYLLSPVDHHPADHPYYTQRNSFQAECVGPFSDPLASSTFPRRHYTSQQELKDEGALVPRTLATKANRIPANLLDQFERQLPLSRDGYHTLQYKRTAVEHRSDSPGRIRHLVHSVQKLFTKSHSLEGPSKGSVNGGKASPDESQTVRYGKRSKSKERRSESKARSSASNASPTSPSWWSSDDNLDGDMCLYHTPSGVMTMGRCPDRSASQYFMEAYNTISEQAVKASRSNNDIKCSTCANLPVTLDAPLLKKSAWSSTLTVSRAREVYQKASVNMDQAMVKSEACQQERSCQYLQVPQDEWTGYTPRGKDDEIPCRRMRSGSYIKAMADEDSGDSDTSPKPSPKVAARRESYLRATQPSLTELTTLKISNEHSPKLQIRSHSYLRAVSEVSINRSLDSLDPAGLLTSPKFRSRNESYMRAMSTISQVSEMEVNGQFESVCESVFSELESQAVEALDLPMPGCFRMRSHSYVRAIEKGCSQDDECVSLRSSSPPRTTTTVRTIQSSTVSSCITTYKKTPPPVPPRTTTKPFISITAQSSTESAQDAYMDGQGQRGDMISQSGLSNSTESLDSMKALTAAIEAANAQIHGPASQHMGNNSAAVTTTTTIATVTTEDRKKDFKKNRCLSIGIQVDDAEEPEKTGENKAPSKFQSVGVQVEEEKCFRRFTRSNSVTTAVQADLDFHDNLENSLESIEDNSCPGPMARQFSRDASTSTVSIQGSGNHYHACAADDDFDTDFDPSILPPPDPWIDSITEDPLEAVQRSVCHRDGHWFLKLLQAERDRMEGWCQQMEREERENNLPEDILGKIRTAVGSAQLLMAQKFYQFRELCEENLNPNAHPRPTSQDLAGFWDMLQLSIENISMKFDELHQLKANNWKQMDPLDKKERRAPPPVPKKPAKGPAPLIRERSLESSQRQEARKRLMAAKRAASVRQNSATESAESIEIYIPEAQTRL", "length": 982, "header": "tr|A0A8C2LYD5-1|A0A8C2LYD5_CRIGR Isoform 1 of Disks large-associated protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=LOC100774912 PE=3 SV=1 CANONICAL=A0A8C2LYD5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616297.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035293533", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293533" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LYL0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYL0" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC100766359", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYL0", "locus": {} } ], "crossref": [ { "id": "100766359", "url": "https://www.ncbi.nlm.nih.gov/gene/100766359", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100766359", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100766359", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LPMQFYS", "url": "https://omabrowser.org/oma/group/LPMQFYS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR16676", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16676", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16676:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16676:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14984", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14984", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_035293533", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035293533", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LYL0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LYL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYL0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRAMVVRLGLGLLLLALLLPSQIYCNQTSVALFSSNQCISTAPNPTNATTRAGGSALQSTAGLLSVSLSLLHFYC", "length": 76, "header": "tr|A0A8C2LYL0-1|A0A8C2LYL0_CRIGR Isoform 1 of Signal transducer CD24-like OS=Cricetulus griseus OX=10029 GN=LOC100766359 PE=4 SV=1 CANONICAL=A0A8C2LYL0-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LYL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYL0/entry#A0A8C2LYL0-1", "sequence": { "sequence": "MGRAMVVRLGLGLLLLALLLPSQIYCNQTSVALFSSNQCISTAPNPTNATTRAGGSALQSTAGLLSVSLSLLHFYC", "length": 76, "header": "tr|A0A8C2LYL0-1|A0A8C2LYL0_CRIGR Isoform 1 of Signal transducer CD24-like OS=Cricetulus griseus OX=10029 GN=LOC100766359 PE=4 SV=1 CANONICAL=A0A8C2LYL0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"id": "GO:0030296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030296", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LYL0", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYL0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" }, { "start_pos": 48, "end_pos": 50, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 27, "end_pos": 29 }, { "start_pos": 48, "end_pos": 50 } ] }, "class_list": [], "section_stats": [ { "table_id": 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"sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2LYL6-1", "uniprot_ac": "A0A8C2LYL6", "uniprot_id": "A0A8C2LYL6_CRIGR", "mass": { "chemical_mass": 55440.0, "monoisotopic_mass": 55440.0 }, "refseq": { "ac": "XP_035300689", "name": "archaemetzincin-1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300689" }, "gene_names": [ { "name": "Amz1", "type": "recommended", "evidence": [ { "id": "A0A8C2LYL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYL6" } ] }, { "name": "Amz1", "type": "synonym", "evidence": [ { "id": "XP_035300689", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300689" } ] } ], "protein_names": [ { "name": "Archaemetzincin-1", "type": "synonym", "evidence": [ { "id": "A0A8C2LYL6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYL6/entry#names_and_taxonomy" } ] }, { "name": "archaemetzincin-1", "type": "synonym", "evidence": [ { "id": "XP_035300689", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300689" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048597.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_035300689", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300689" } ] }, { "annotation": "Probable zinc metalloprotease.", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LYL6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYL6#function" }, { "database": "UniProtKB", "id": "ARBA00024316", "url": "https://www.uniprot.org/uniprotkb/ARBA00024316#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LYL6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYL6" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Amz1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYL6", "locus": {} } ], "crossref": [ { "id": "cd11375", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11375", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100761231", "url": "https://www.ncbi.nlm.nih.gov/gene/100761231", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012962", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012962", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100761231", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761231", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LAKWEMF", "url": "https://omabrowser.org/oma/group/LAKWEMF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LYL6", "url": "https://www.orthodb.org/?gene=A0A8C2LYL6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32205", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32205", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32205:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32205:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_035300689", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_035300689", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LYL6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LYL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYL6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLQCRPPQEFSFGPRALKDALISRDLALKQLYTSAFSPSERLFLSEAYNPHRTLFSTLLIHSAFDWLLSRPEAPEDFETFHASLQPRKQSLARKHIYLQPIDLSEGLAGCPLLDHLRNCAEAFFLGLRVKCLPSVAAASIHCSSRPSQDTDGLQLHTDGILSFLKNNKPGDALCVLGLTLADLYPHDAWTFTFGRFLPGHEVGVCSFARFSGEFLQAGPSLPDPALLEAAADDPETLPHEGGRTLCFSALGMVQCCKVTCHELCHLLGLGSCRWLRCLLQGALSLDEAIRRPLDLCPICLRKLQHLLGFRLLERYKRLHTWTRVMVEMWSGQEAGEPSVSDDTLPFSADSGMGCESDTEPVTSPSEPVTPDAWSHVFPDGPEPGSEDGLSSLVASEVLLKLGGPIEAIEEYGQWLGACIQVLEREVAEEELVHVDAAVDAMGRWEMFTGQLPVTRQHLPCVKDNVGLRRVLGDKFFSLRRRLSSRRLAKASSSHCRWGAEN", "length": 501, "header": "tr|A0A8C2LYL6-1|A0A8C2LYL6_CRIGR Isoform 1 of Archaemetzincin-1 OS=Cricetulus griseus OX=10029 GN=Amz1 PE=3 SV=1 CANONICAL=A0A8C2LYL6-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LYL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYL6/entry#A0A8C2LYL6-1", "sequence": { "sequence": "MLQCRPPQEFSFGPRALKDALISRDLALKQLYTSAFSPSERLFLSEAYNPHRTLFSTLLIHSAFDWLLSRPEAPEDFETFHASLQPRKQSLARKHIYLQPIDLSEGLAGCPLLDHLRNCAEAFFLGLRVKCLPSVAAASIHCSSRPSQDTDGLQLHTDGILSFLKNNKPGDALCVLGLTLADLYPHDAWTFTFGRFLPGHEVGVCSFARFSGEFLQAGPSLPDPALLEAAADDPETLPHEGGRTLCFSALGMVQCCKVTCHELCHLLGLGSCRWLRCLLQGALSLDEAIRRPLDLCPICLRKLQHLLGFRLLERYKRLHTWTRVMVEMWSGQEAGEPSVSDDTLPFSADSGMGCESDTEPVTSPSEPVTPDAWSHVFPDGPEPGSEDGLSSLVASEVLLKLGGPIEAIEEYGQWLGACIQVLEREVAEEELVHVDAAVDAMGRWEMFTGQLPVTRQHLPCVKDNVGLRRVLGDKFFSLRRRLSSRRLAKASSSHCRWGAEN", "length": 501, "header": "tr|A0A8C2LYL6-1|A0A8C2LYL6_CRIGR Isoform 1 of Archaemetzincin-1 OS=Cricetulus griseus OX=10029 GN=Amz1 PE=3 SV=1 CANONICAL=A0A8C2LYL6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LYL6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYL6" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LYL6", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYL6" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100761231", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100761231", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QFK7-1", "protein_name": "Archaelysin family metallopeptidase 1", "gene_name": "AMZ1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLQCRPAQEFSFGPRALKDALVSTDPGLRQLYAAAFSPAERLFLAEAYNPRRTLFGAPRIHTAFDWLLSRPEAPEDFETFHAALPPRKQSPARKHIYLQPIDLSEGLAGGALLYHLRSCTEAFFLGLQVRCLPSVAAASIHCSSRLSQDSDRLQLHTDGILSFLKSSKPGDACVLGLTLSDLYPCEAWTFTFGKFLPGHEVGVCSFARFSEEFLQLGPSAPDVALAEVAADGPEVPLQDTGQTVCFSALGMLQCCKVTCHELCHLLGLGSCRWLRCLMQGALSLDEALRRPLDLCPICLRKLQHILGFRLVDRYKRLYLWTQAVAGTQTGEEAAGEPSASVSEDTLPCSADSGLCCESDSEPGTSLSEPLSPDAWSHAFPAGAELEPEDGLGALAAAEGPGEALAEHGRWLAACIQALERAVTEEELARVDSAVDALARWEMFTGQLPAPRHDLPCGQDSAGLRRILGGTFSSLRRRLSARRLARAEVSPRRGKAEEN", "length": 498 }, "evidence": [ { "id": "A0A8C2LYL6", "url": "https://omabrowser.org/oma/group/A0A8C2LYL6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0ZCN5-1", "protein_name": "Archaelysin family metallopeptidase 2", "gene_name": "AMZ2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLQCKHTQEFSFGPRALKDALISTNPALQELYAKAFSRAEKLFLSEAYNPQRTLFCTLLIRTAFDWLLSHPDAPEDFETFYHAMLRRKQSFCRKHIYLQPIDLTEGPAGPSLLDSLQSCVESFFLGLRVKCLPSIPISSIHCCYRHSRDSDRVQLHADGILNFLKNNKPMDALCVLGLTLTDLYPCETWSFTFSKFLPGQEVGVCSFARFSGDFPQASCSSLNPLTHREQLSDVSKESRERTLPFSAQEMVQCCKVTCHEICHLMGLGTCRWLQCIMQGALSLDEALLRPLEPCPICLRKLQHIVGFKLVERYRKLYAWTQTVLSTWPKQEPADLSASEDVLPLSSDSGMCCENDSEAVTSLSEPLTPDVCSQALSIGPELEQDERSCSLAEVQSQPQPAGPSQPTDVIKDYELWLEMCIAALERNVSEEELARVDKAVDALARWDMFTGQLPAMKKDLPFVRDNTGLRKVLGDKFSSLRRKLSSRKLSKGESSPHRWRWEDN", "length": 503 }, "evidence": [ { "id": "A0A8C2LYL6", "url": "https://omabrowser.org/oma/group/A0A8C2LYL6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E1B9T4-1", "protein_name": "Archaelysin family metallopeptidase 1", "gene_name": "AMZ1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLQCRPAEEFSFGPRALKDALLSTDPALRQLYTAAFSPAERLFLAEAYNPRRTLFGTLLIRTAFDWLLSRPEAPEDFQTFHAALPPRKQSLARKHIYLQPIGLSEGPAGSVLLDQLRSCTEAFFLGLQVRCLPSVAAASIHCSSRPGQDPDRLQLHTDGILSFLKSSKPGDALCVLGLTLSDLYPCEAWTFTFGTFLPGHEVGVCSFARFSGEFLPRGPSTPDLVEVEAEAAADGPEVPLQDGGQAVCFSALGMVQCCKVTCHELCHLLGLGNCRWLRCLMQGALRVDEALRRPLDLCPICLRKLQHLLGFRLVDRYKRLYAWTQAAAGTQPSPAAVGEPSVSEDTLPCSADSGLCCESDSEPGSSLSEPLSPDAWIPAGLELDAEDGLGSLAAAEGPGEALAEHGRWLAACIQALERDVSEGELERVDGAVDALAPWDLFTGRLPASRQDLPCGRDGAGLRRVLGDTFSSLRRRLSARRPSRAESPLRRQKAEDD", "length": 496 }, "evidence": [ { "id": "A0A8C2LYL6", "url": "https://omabrowser.org/oma/group/A0A8C2LYL6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q400C9-1", "protein_name": "Archaemetzincin-1", "gene_name": "Amz1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVQCRPPQEFSFGPRALKDALISCDLALKQLYTSAFSPSERLFLSEAYNPHRTLFSTLLIHSAFDWLLSRPEAPEDFETFHASLQLRKQSLARKHIYLQPIDLSEGLAGCPLLDHLRSCAEAFFLGLRVKCLPSVASASINCCSRPARDTDGLQLHTDGILSFLKNNKPGDALCVLGLTLADLYPHDAWTFTFGRFLPGHEVGVCSFARFSGEFLQAGSSIPDSALLEAAAGGPETLPQEGGQTLCYSALGMVQCCKVTCHELCHLLGLGSCRWLRCLLQGVLSLDEALRRPLDLCPICLRKLHHLLGFRLLERYKRLHTWTRVMLEMWSGQEAGEPSVSEDTLPFSADSGMGCESDTEPVTSPSEPVTPDAWSHTFPDGPEPVSEEGLSSLAASEVLLKLGGPVDALEEYRQWLDACIQALEREVAEEELVQVDAAVDALGRWEMFTGQLPVTKQYMPCVKDNVGLRRVLGDKFSSLRRRLSSRRLAKASSSQCHWGAEN", "length": 501 }, "evidence": [ { "id": "A0A8C2LYL6", "url": "https://omabrowser.org/oma/group/A0A8C2LYL6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q400G9-1", "protein_name": "Archaemetzincin-1", "gene_name": "AMZ1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614707.1) and transcript sequence (IACG01091705.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003509458", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509458" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LYP1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYP1" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Chchd7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYP1", "locus": {} } ], "crossref": [ { "id": "100755404", "url": "https://www.ncbi.nlm.nih.gov/gene/100755404", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009069", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009069", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048280", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048280", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051040", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051040", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755404", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755404", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QELSYKC", "url": "https://omabrowser.org/oma/group/QELSYKC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2LYP1", "url": "https://www.orthodb.org/?gene=A0A8C2LYP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46811", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46811", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46811:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46811:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02297", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02297", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003509458", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003509458", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LYP1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LYP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYP1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPIVTRRLRDPDINPCLSESDASTRCMDENNYDRERCSNYFLKYKNCRRFWNSVMIQRRQNGVQPSMPTAAERDEILRAMQKMPY", "length": 85, "header": "tr|A0A8C2LYP1-1|A0A8C2LYP1_CRIGR Isoform 1 of Coiled-coil-helix-coiled-coil-helix domain-containing protein 7 OS=Cricetulus griseus OX=10029 GN=Chchd7 PE=3 SV=1 CANONICAL=A0A8C2LYP1-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LYP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LYP1/entry#A0A8C2LYP1-1", "sequence": { "sequence": "MPIVTRRLRDPDINPCLSESDASTRCMDENNYDRERCSNYFLKYKNCRRFWNSVMIQRRQNGVQPSMPTAAERDEILRAMQKMPY", "length": 85, "header": "tr|A0A8C2LYP1-1|A0A8C2LYP1_CRIGR Isoform 1 of Coiled-coil-helix-coiled-coil-helix domain-containing protein 7 OS=Cricetulus griseus OX=10029 GN=Chchd7 PE=3 SV=1 CANONICAL=A0A8C2LYP1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048602.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027286341", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286341" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LZV2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZV2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Fam98c", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZV2", "locus": {} } ], "crossref": [ { "id": "100765434", "url": "https://www.ncbi.nlm.nih.gov/gene/100765434", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018797", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018797", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100765434", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765434", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2LZV2", "url": "https://www.orthodb.org/?gene=A0A8C2LZV2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31353", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31353", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31353:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31353:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10239", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10239", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027286341", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027286341", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2LZV2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2LZV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZV2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GJV0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GJV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GJV0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGATVAGDLLTLGYGALPEAASRGPACADFRALCARLAAELTALGAVERREEGALGLGAGHGPDAEEEFLRQLAGLLRALHCPDRALGGGNCATALREPGGGLRLLRFLCSELQAARLLHLRLPLDASPAQSIGEGTKEGNGMVQELMLTLQALGLPRPVRGTLASQLVREFHGKVSELLPSLPPESMQPLLSSPLDASQWEALESLSQSLTEQYCCRRCLLLKRLDLTTSAFHWGDRAEGQGEAMKAVLFPIRGLLTPESDVSVAHVLAARADLSRLVPATSVAARQGTSCAINKVLMGDVPDRGGRPDELEAPMPAWQSRREDGGRGKAGPQRWGRRKKKKK", "length": 345, "header": "tr|A0A8C2LZV2-1|A0A8C2LZV2_CRIGR Isoform 1 of Protein FAM98C isoform X2 OS=Cricetulus griseus OX=10029 GN=Fam98c PE=3 SV=1 CANONICAL=A0A8C2LZV2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2LZV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZV2/entry#A0A8C2LZV2-1", "sequence": { "sequence": "MDGATVAGDLLTLGYGALPEAASRGPACADFRALCARLAAELTALGAVERREEGALGLGAGHGPDAEEEFLRQLAGLLRALHCPDRALGGGNCATALREPGGGLRLLRFLCSELQAARLLHLRLPLDASPAQSIGEGTKEGNGMVQELMLTLQALGLPRPVRGTLASQLVREFHGKVSELLPSLPPESMQPLLSSPLDASQWEALESLSQSLTEQYCCRRCLLLKRLDLTTSAFHWGDRAEGQGEAMKAVLFPIRGLLTPESDVSVAHVLAARADLSRLVPATSVAARQGTSCAINKVLMGDVPDRGGRPDELEAPMPAWQSRREDGGRGKAGPQRWGRRKKKKK", "length": 345, "header": "tr|A0A8C2LZV2-1|A0A8C2LZV2_CRIGR Isoform 1 of Protein FAM98C isoform X2 OS=Cricetulus griseus OX=10029 GN=Fam98c PE=3 SV=1 CANONICAL=A0A8C2LZV2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GJV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZV2/entry#A0A9J7GJV0-1", "sequence": { "sequence": "MDGATVAGDLLTLGYGALPEAASRGPACADFRALCARLAAELTALGAVERREEGALGLGAGHGFLCSELQAARLLHLRLPLDASPAQSIGEGTKEGNGMVQELMLTLQALGLPRPVRGTLASQLVREFHGKVSELLPSLPPESMQPLLSSPLDASQWEALESLSQSLTEQYCCRRCLLLKRLDLTTSAFHWGDRAEGQGEAMKAVLFPIRGLLTPESDVSVAHVLAARADLSRLVPATSVAARQGTSCAINKVLMGDVPDRGGRPDELEAPMPAWQSRREDGGRGKAGPQRWGRRKKKKK", "length": 300, "header": "tr|A0A9J7GJV0-1|A0A9J7GJV0_CRIGR Computationally mapped isoform of Protein FAM98C isoform X3 OS=Cricetulus griseus OX=10029 GN=Fam98c PE=3 SV=1 CANONICAL=A0A8C2LZV2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"UniProtKB", "id": "A0A8C2LZZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZZ3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2LZZ3", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZZ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2LZZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2LZZ3" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": 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"count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2M007-1", "uniprot_ac": "A0A8C2M007", "uniprot_id": "A0A8C2M007_CRIGR", "mass": { "chemical_mass": 23032.0, "monoisotopic_mass": 23032.0 }, "refseq": { "ac": "XP_007635485", "name": "putative endogenous retrovirus group FC1 Env polyprotein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007635485" }, "gene_names": [ { "name": "LOC103159524", "type": "recommended", "evidence": [ { "id": "A0A8C2M007", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M007" } ] }, { "name": "LOC103159524", "type": "synonym", "evidence": [ { "id": "XP_007635485", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007635485" } ] } ], "protein_names": [ { "name": "Endogenous retrovirus group FC1 Env polyprotein", "type": "synonym", "evidence": [ { "id": "A0A8C2M007", "database": "UniProtKB", "url": 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This record is derived from a genomic sequence (NW_003613715.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_007635485", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007635485" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M007", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M007" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC103159524", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M007", "locus": {} } ], "crossref": [ { "id": "103159524", "url": "https://www.ncbi.nlm.nih.gov/gene/103159524", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "cge:103159524", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103159524", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2M007", "url": "https://www.orthodb.org/?gene=A0A8C2M007", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "XP_007635485", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_007635485", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2M007", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M007", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M007-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M007-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGFNLMMLFCLAIFPSVLSWNPNWKCQPPRAPIPTKPTPRAWKFHVLALENLNKTIASTFCPITGCASTISLTFDIRDTCQGKCINDFYNAMSSPIYVCFVYEQTRSDCQDPNYGGCPHWGCKYHSTWPRWGGENPSRLNSVDWHTKVTYSIPDPWNDRWRTGVVGYVYRHNERDTAFDGKTKILIFRALAKFTPQNSFI", "length": 200, "header": "tr|A0A8C2M007-1|A0A8C2M007_CRIGR Isoform 1 of Endogenous retrovirus group FC1 Env polyprotein OS=Cricetulus griseus OX=10029 GN=LOC103159524 PE=4 SV=1 CANONICAL=A0A8C2M007-1" }, "isoforms": [ { "isoform_ac": "A0A8C2M007-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M007/entry#A0A8C2M007-1", "sequence": { "sequence": "MGFNLMMLFCLAIFPSVLSWNPNWKCQPPRAPIPTKPTPRAWKFHVLALENLNKTIASTFCPITGCASTISLTFDIRDTCQGKCINDFYNAMSSPIYVCFVYEQTRSDCQDPNYGGCPHWGCKYHSTWPRWGGENPSRLNSVDWHTKVTYSIPDPWNDRWRTGVVGYVYRHNERDTAFDGKTKILIFRALAKFTPQNSFI", "length": 200, "header": "tr|A0A8C2M007-1|A0A8C2M007_CRIGR Isoform 1 of Endogenous retrovirus group FC1 Env polyprotein OS=Cricetulus griseus OX=10029 GN=LOC103159524 PE=4 SV=1 CANONICAL=A0A8C2M007-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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member 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003508969", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508969" }, { "id": "A0A8C2M088", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M088/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003614609.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003508969", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508969" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M088", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M088" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tox2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M088", "locus": {} } ], "crossref": [ { "id": "cd21995", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21995", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100772087", "url": "https://www.ncbi.nlm.nih.gov/gene/100772087", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051365", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051365", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100772087", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772087", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MGMNEAN", "url": "https://omabrowser.org/oma/group/MGMNEAN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2M088", "url": "https://www.orthodb.org/?gene=A0A8C2M088", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45781", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45781", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45781:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45781:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00505", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00505", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003508969", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003508969", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2M088", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M088", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M088-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M088-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QGV7", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QGV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2QGV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2QGV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZS6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZS6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GZS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GZS6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H4U7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4U7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H4U7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H4U7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JWE1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JWE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JWE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JWE1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQQHLSEAVAGAFSRCLGFCGMRLRLLLSRHWCIAGASLQKFDGDSAYVGMSDGNPELLPTSQTYNSQSESNEDYEIPPITPPNLPEPSLLHLGDHEASYHSLCHGLAPNGLLPAYPYQAMDLPAIMVSNMLAQDSHLLSGQLPTIQEMVHSEVAAYDSGRPGPLLGRPAMLASHMSALSQSQLISQMGIRSGIAHSSPSPPGSKSATPSPSSSTQEEESDAHFKISGEKRPSADPGKKAKNPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQAYKRKTEAAKKEYLKALAAYRASLVSKSPPDQGEAKNAQANPPAKMLPPKQPMYAMPGLASFLTPSDLQAFRTGASPASLARTLGSKALLPGLSTSPPPPSFPLSPSLHQQLPLPPHAQGTLLSPPLSMSPAPQPPVLPASMALQVQLAMSPSPPGPQDFPHISEFPSGSGSRSPGPSNPSSGGDWDGSYPSGERGLGTCRLCRGSPPPTTSPKNLQEPSAR", "length": 523, "header": "tr|A0A8C2M088-1|A0A8C2M088_CRIGR Isoform 1 of TOX high mobility group box family member 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tox2 PE=4 SV=1 CANONICAL=A0A8C2M088-1" }, "isoforms": [ { "isoform_ac": "A0A8C2M088-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M088/entry#A0A8C2M088-1", "sequence": { "sequence": "MQQHLSEAVAGAFSRCLGFCGMRLRLLLSRHWCIAGASLQKFDGDSAYVGMSDGNPELLPTSQTYNSQSESNEDYEIPPITPPNLPEPSLLHLGDHEASYHSLCHGLAPNGLLPAYPYQAMDLPAIMVSNMLAQDSHLLSGQLPTIQEMVHSEVAAYDSGRPGPLLGRPAMLASHMSALSQSQLISQMGIRSGIAHSSPSPPGSKSATPSPSSSTQEEESDAHFKISGEKRPSADPGKKAKNPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQAYKRKTEAAKKEYLKALAAYRASLVSKSPPDQGEAKNAQANPPAKMLPPKQPMYAMPGLASFLTPSDLQAFRTGASPASLARTLGSKALLPGLSTSPPPPSFPLSPSLHQQLPLPPHAQGTLLSPPLSMSPAPQPPVLPASMALQVQLAMSPSPPGPQDFPHISEFPSGSGSRSPGPSNPSSGGDWDGSYPSGERGLGTCRLCRGSPPPTTSPKNLQEPSAR", "length": 523, "header": "tr|A0A8C2M088-1|A0A8C2M088_CRIGR Isoform 1 of TOX high mobility group box family member 2 isoform X1 OS=Cricetulus griseus OX=10029 GN=Tox2 PE=4 SV=1 CANONICAL=A0A8C2M088-1" }, "locus": {} }, { "isoform_ac": "A0A8C2QGV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M088/entry#A0A8C2QGV7-1", "sequence": { "sequence": "MDVRLYPSAPAVGARAGAEPAGLAHLDYYHCGKFDGDSAYVGMSDGNPELLPTSQTYNSQSESNEDYEIPPITPPNLPEPSLLHLGDHEASYHSLCHGLAPNGLLPAYPYQAMDLPAIMVSNMLAQDSHLLSGQLPTIQEMVHSEVAAYDSGRPGPLLGRPAMLASHMSALSQSQLISQMGIRSGIAHSSPSPPGSKSATPSPSSSTQEEESDAHFKISGEKRPSADPGKKAKNPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQAYKRKTEAAKKEYLKALAAYRASLVSKSPPDQGEAKNAQANPPAKMLPPKQPMYAMPGLASFLTPSDLQAFRTGASPASLARTLGSKALLPGLSTSPPPPSFPLSPSLHQQLPLPPHAQGTLLSPPLSMSPAPQPPVLPASMALQVQLAMSPSPPGPQDFPHISEFPSGSGSRSPGPSNPSSGGDWDGSYPSGERGLGTCSLLPRDKSLYLT", "length": 505, "header": "tr|A0A8C2QGV7-1|A0A8C2QGV7_CRIGR Computationally mapped isoform of TOX high mobility group box family member 2 isoform X5 OS=Cricetulus griseus OX=10029 GN=Tox2 PE=4 SV=1 CANONICAL=A0A8C2M088-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GZS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M088/entry#A0A9J7GZS6-1", "sequence": { "sequence": "MQQHLSEAVAGAFSRCLGFCGMRLRLLLSRHWCIAGASLQKFDGDSAYVGMSDGNPELLPTSQTYNSQSESNEDYEIPPITPPNLPEPSLLHLGDHEASYHSLCHGLAPNGLLPAYPYQAMDLPAIMVSNMLAQDSHLLSGQLPTIQEMVHSEVAAYDSGRPGPLLGRPAMLASHMSALSQSQLISQMGIRSGIAHSSPSPPGSKSATPSPSSSTQEEESDAHFKISGEKRPSADPGKKAKNPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQAYKRKTEAAKKEYLKALAAYRASLVSKSPPDQGEAKNAQANPPAKMLPPKQPMYAMPGLASFLTPSDLQAFRTGASPASLARTLGSKALLPGLSTSPPPPSFPLSPSLHQQLPLPPHAQGTLLSPPLSMSPAPQPPVLPASMALQVQLAMSPSPPGPQDFPHISEFPSGSGSRSPGPSNPSSGGDWDGSYPSGERGLGTCSLLPRDKSLYLT", "length": 513, "header": "tr|A0A9J7GZS6-1|A0A9J7GZS6_CRIGR Computationally mapped isoform of TOX high mobility group box family member 2 isoform X2 OS=Cricetulus griseus OX=10029 GN=Tox2 PE=4 SV=1 CANONICAL=A0A8C2M088-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H4U7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M088/entry#A0A9J7H4U7-1", "sequence": { "sequence": "MQQHLSEAVAGAFSRCLGFCGMRLRLLLSRHWCIAGASLQKFDGDSAYVGMSDGNPELLPTSQTYNSQSESNEDYEIPPITPPNLPEPSLLHLGDHEASYHSLCHGLAPNGLLPAYPYQAMDLPAIMVSNMLAQDSHLLSGQLPTIQEMVHSEVAAYDSGRPGPLLGRPAMLASHMSALSQSQLISQMGIRSGIAHSSPSPPGSKSATPSPSSSTQEEESDAHFKISGEKRPSADPGKKAKNPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQSPPDQGEAKNAQANPPAKMLPPKQPMYAMPGLASFLTPSDLQAFRTGASPASLARTLGSKALLPGLSTSPPPPSFPLSPSLHQQLPLPPHAQGTLLSPPLSMSPAPQPPVLPASMALQVQLAMSPSPPGPQDFPHISEFPSGSGSRSPGPSNPSSGGDWDGSYPSGERGLGTCSLLPRDKSLYLT", "length": 486, "header": "tr|A0A9J7H4U7-1|A0A9J7H4U7_CRIGR Computationally mapped isoform of TOX high mobility group box family member 2 isoform X3 OS=Cricetulus griseus OX=10029 GN=Tox2 PE=4 SV=1 CANONICAL=A0A8C2M088-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JWE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M088/entry#A0A9J7JWE1-1", "sequence": { "sequence": "MDVRLYPSAPAVGARAGAEPAGLAHLDYYHCGKFDGDSAYVGMSDGNPELLPTSQTYNSQSESNEDYEIPPITPPNLPEPSLLHLGDHEASYHSLCHGLAPNGLLPAYPYQAMDLPAIMVSNMLAQDSHLLSGQLPTIQEMVHSEVAAYDSGRPGPLLGRPAMLASHMSALSQSQLISQMGIRSGIAHSSPSPPGSKSATPSPSSSTQEEESDAHFKISGEKRPSADPGKKAKNPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQAYKRKTEAAKKEYLKALAAYRASLVSKSPPDQGEAKNAQANPPAKMLPPKQPMYAMPGLASFLTPSDLQAFRTGASPASLARTLGSKALLPGLSTSPPPPSFPLSPSLHQQLPLPPHAQGTLLSPPLSMSPAPQPPVLPASMALQVQLAMSPSPPGPQDFPHISEFPSGSGSRSPGPSNPSSGGDWDGSYPSGERGLGTCRLCRGSPPPTTSPKNLQEPSAR", "length": 515, "header": "tr|A0A9J7JWE1-1|A0A9J7JWE1_CRIGR Computationally mapped isoform of TOX high mobility group box family member 2 isoform X4 OS=Cricetulus griseus OX=10029 GN=Tox2 PE=4 SV=1 CANONICAL=A0A8C2M088-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 208, "start_aa": "Thr", "end_pos": 208, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr208", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 81, "start_aa": "Thr", "end_pos": 81, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr81", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M088", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M088" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M088", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M088" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100772087", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100772087", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2A472-1", "protein_name": "TOX high mobility group box family member 2", "gene_name": "Tox2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGGGGAGPPANRGPRVVGRLIKLLFLAFFSLSVLIMQQHLTEAVAGAFSRCLGFRGMRLRLLTRHWCIAGASLQKFDGDSAYVGMSDGNPELLSTSQTYNSQGESNEDYEIPPITPPNLPEPSLLHLGDHEAGYHSLCHGLAPNGLLPAYSYQAMDLPAIMVSNMLAQDGHLLSGQLPTIQEMVHSEVAAYDSGRPGPLLGRPAMLASHMSALSQSQLISQMGIRSGIAHGSPSPPGSKSATPSPSSSTQEEESDAHFKISGEKRPSVDPGKKAKNPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQAYKRKTEAAKKEYLKALAAYRASLVSKSPPDQGEAKNTQANPPAKMLPPKQPMYAMPGLASFLTPSDLQAFRSGASPASLARTLGSKALLPGLSTSPPPPSFPLSPSLHQQLPLPPHAQGTLLSPPLSMSPAPQPPVLPASMALQVQLAMSPSPPGPQDFPHISDFSSGSGSRSPGPSNPSSSGDWDGSYPSGERGLGTCSLLPRDKSLYLT", "length": 547 }, "evidence": [ { "id": "A0A8C2M088", "url": "https://omabrowser.org/oma/group/A0A8C2M088/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q76IQ7-1", "protein_name": "TOX high mobility group box family member 2", "gene_name": "Tox2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSDGNPELLSTSQTYNSQGESNEDYEIPPITPPNLPEPSLLHLGDHEAGYHSLCHGLAPNGLLPAYSYQAMDLPAIMVSNMLAQDGHLLSGQLPTIQEMVHSEVAAYDSGRPGPLLGRPAMLASHMSALSQSQLISQMGLRSGIAHSSPSPPGSKSATPSPSSSTQEEESDAHFKISGEKRPSTDPGKKAKNPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQAYKRKTEAAKKEYLKALAAYRASLVSKSPPDQGEAKNAQANPPAKMLPPKQPMYAMPGLASFLTPSDLQAFRSAASPASLARTLGSKALLPGLSTSPPPPSFPLSPSLHQQLPLPPHAQGTLLSPPLSMSPAPQPPVLPAPMALQVQLAMSPSPPGPQDFPHISDFPSGSGSRSPGPSNPSSSGDWDGSYPSGERGLGTCRLCRSSPPPTTSPKNLQEPSAR", "length": 473 }, "evidence": [ { "id": "A0A8C2M088", "url": "https://omabrowser.org/oma/group/A0A8C2M088/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96NM4-1", "protein_name": "TOX high mobility group box family member 2", "gene_name": "TOX2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQQTRTEAVAGAFSRCLGFCGMRLGLLLLARHWCIAGVFPQKFDGDSAYVGMSDGNPELLSTSQTYNGQSENNEDYEIPPITPPNLPEPSLLHLGDHEASYHSLCHGLTPNGLLPAYSYQAMDLPAIMVSNMLAQDSHLLSGQLPTIQEMVHSEVAAYDSGRPGPLLGRPAMLASHMSALSQSQLISQMGIRSSIAHSSPSPPGSKSATPSPSSSTQEEESEVHFKISGEKRPSADPGKKAKNPKKKKKKDPNEPQKPVSAYALFFRDTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQSSPDQGETKSTQANPPAKMLPPKQPMYAMPGLASFLTPSDLQAFRSGASPASLARTLGSKSLLPGLSASPPPPPSFPLSPTLHQQLSLPPHAQGALLSPPVSMSPAPQPPVLPTPMALQVQLAMSPSPPGPQDFPHISEFPSSSGSCSPGPSNPTSSGDWDSSYPSGECGISTCSLLPRDKSLYLT", "length": 488 }, "evidence": [ { "id": "A0A8C2M088", "url": "https://omabrowser.org/oma/group/A0A8C2M088/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M088", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M088" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M088", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M088" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "chromatin DNA binding", "id": "GO:0031490", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031490", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M088", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M088" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2M088", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M088" }, { "id": "PS50118", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50118" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HMG box", "eco_id": "ECO_0000259", "start_pos": 254, "end_pos": 322, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 81, 208 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027266595", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266595" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M0D9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0D9" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Atmin", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0D9", "locus": {} } ], "crossref": [ { "id": "103162505", "url": "https://www.ncbi.nlm.nih.gov/gene/103162505", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] 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"locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"A0A8C2M0R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0R8" } ] }, { "name": "LOC100765452", "type": "recommended", "evidence": [ { "id": "A0A8C2M0R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0R8" } ] }, { "name": "Krt18", "type": "synonym", "evidence": [ { "id": "XP_003514107", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514107" } ] } ], "protein_names": [ { "name": "Keratin, type I cytoskeletal 18", "type": "synonym", "evidence": [ { "id": "A0A8C2M0R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0R8/entry#names_and_taxonomy" } ] }, { "name": "keratin, type I cytoskeletal 18", "type": "synonym", "evidence": [ { "id": "XP_003514107", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514107" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003616319.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003514107", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514107" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M0R8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0R8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Krt18", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0R8", "locus": {} } ], "crossref": [ { "id": "100759201", "url": "https://www.ncbi.nlm.nih.gov/gene/100759201", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "100765452", "url": "https://www.ncbi.nlm.nih.gov/gene/100765452", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002957", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002957", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018039", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018039", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759201", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759201", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "cge:100765452", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765452", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IHSTKIV", "url": "https://omabrowser.org/oma/group/IHSTKIV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2M0R8", "url": "https://www.orthodb.org/?gene=A0A8C2M0R8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A9J7JU34", "url": "https://www.orthodb.org/?gene=A0A9J7JU34", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23239", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23239", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23239:SF349", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23239:SF349", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003514107", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003514107", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2M0R8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0R8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M0R8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0R8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JU34", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JU34-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JU34-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSFTTRSTTFSTNYRSLGSVRTPSQRVRPASSAASVYAGAGGSGSRISVSRSTNVWGGSVGSAGLVGMGGIQTEKETMQDLNDRLASYLDRVKSLETENRRLESKIREHLEKKGSQGVRDWGHYFKTIEDLRAQIFANSVDNARIVLQIDNARLAADDFRVKYETELAMRQSVESDIHGLRKVVDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLEAQIASSGLTVEVDAPKSQDLSKIMADIRAQYEELAQKNREELDKYWSQQIEESTTVVTTQSAEIRDAETTLTDLRRTFQALEIDLDAMKNQKISLENSLRDVEARYSAQMEQLNGVLLHLESELAQTRAEGQRQTQEYEALLNIKVKLEAEIATYRRLLEDGEDFSLSDALDSSNSMQTVQRTTTRKVVDGKVVSETNDTRVLRH", "length": 425, "header": "tr|A0A8C2M0R8-1|A0A8C2M0R8_CRIGR Isoform 1 of Keratin, type I cytoskeletal 18 OS=Cricetulus griseus OX=10029 GN=Krt18 PE=3 SV=1 CANONICAL=A0A8C2M0R8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2M0R8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0R8/entry#A0A8C2M0R8-1", "sequence": { "sequence": "MSFTTRSTTFSTNYRSLGSVRTPSQRVRPASSAASVYAGAGGSGSRISVSRSTNVWGGSVGSAGLVGMGGIQTEKETMQDLNDRLASYLDRVKSLETENRRLESKIREHLEKKGSQGVRDWGHYFKTIEDLRAQIFANSVDNARIVLQIDNARLAADDFRVKYETELAMRQSVESDIHGLRKVVDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLEAQIASSGLTVEVDAPKSQDLSKIMADIRAQYEELAQKNREELDKYWSQQIEESTTVVTTQSAEIRDAETTLTDLRRTFQALEIDLDAMKNQKISLENSLRDVEARYSAQMEQLNGVLLHLESELAQTRAEGQRQTQEYEALLNIKVKLEAEIATYRRLLEDGEDFSLSDALDSSNSMQTVQRTTTRKVVDGKVVSETNDTRVLRH", "length": 425, "header": "tr|A0A8C2M0R8-1|A0A8C2M0R8_CRIGR Isoform 1 of Keratin, type I cytoskeletal 18 OS=Cricetulus griseus OX=10029 GN=Krt18 PE=3 SV=1 CANONICAL=A0A8C2M0R8-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JU34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0R8/entry#A0A9J7JU34-1", "sequence": { "sequence": "MSFTTRSTTFSTNYWSLSSVRTPSQRVRPASSAASIYAGAGGLGSRISVSRSTNVWGGSVGSAGLVGMGGIQTEKETMQDLNDCLASYLDRVKSLETENRRLESKIRKHLEKKGSQGIRDWGHYFKTIEDLRAQIFANSVDNACIVLQIDNARLAADDFRVKYETDLAMRQSVESDIHGLRKVVDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLEAQIASSGLTVEVDAPKSQDHSKIMADIRAQYEELAXKNREELDKYWSXQIEERTTVVTTQSAEIRDAETTLTDPRRTFQALEIDLDAMKNQKISLENSLRDVEARYSAQMEQLNGVLLHLELELAQTLAEGQRQTQEYEALLNIKVKLKAEIATYRHLLEDGEDFSLSDALDSSNSXQTVQRTTTRKVVDGNVVSETNDTRVLRH", "length": 425, "header": "tr|A0A9J7JU34-1|A0A9J7JU34_CRIGR Computationally mapped isoform of LOW QUALITY PROTEIN: keratin, type I cytoskeletal 18-like OS=Cricetulus griseus OX=10029 GN=LOC100765452 PE=3 SV=1 CANONICAL=A0A8C2M0R8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M0R8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0R8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M0R8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0R8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100759201", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759201", "resource": "KEGG Pathway" }, { "id": "cge:100765452", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765452", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1A2T7-1", "protein_name": "Keratin 18", "gene_name": "KRT18", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSLSRSTTFSTSSRTGSIRRLGPHSSAASVYAGAGGSGSRISITRTASTYGGGYGGGYGGGYGAGYGGGLLLSGSGVVQNEKETMQDLNERLATYLEKVRSLENNNRRLEAQIRESLAKRGPSTRDWGNYWDTIQQLRDKIYDSAVENARTVLQIDNARLAADDFRVKYEAELAIRTSVESDISGLRKVLDDTNMARLQLEGEIEALREELIFMKKNHEEEVNALQGQAASAGLTVEVDAPQAQDLGQALAELRAQYDALAKKNVEELEKQWGQQISETTLEVTQSTKEVDTARSRLLELRRSVQSLEIDLDALRSQNAGLEGSLAETEARYGAQLEQLQGLILRGEEELAQARAELQRQNREHCALQDAKSKLEAEIATYRALLEGGEGFSLQDALGSEGTVTTQRSTQRMVDGKVVSESKEVKVRSY", "length": 429 }, "evidence": [ { "id": "A0A8C2M0R8", "url": "https://omabrowser.org/oma/group/A0A8C2M0R8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P05783-1", "protein_name": "Keratin, type I cytoskeletal 18", "gene_name": "KRT18", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSFTTRSTFSTNYRSLGSVQAPSYGARPVSSAASVYAGAGGSGSRISVSRSTSFRGGMGSGGLATGIAGGLAGMGGIQNEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQVRDWSHYFKIIEDLRAQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRLQLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYDELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLKASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEIATYRRLLEDGEDFNLGDALDSSNSMQTIQKTTTRRIVDGKVVSETNDTKVLRH", "length": 430 }, "evidence": [ { "id": "A0A8C2M0R8", "url": "https://omabrowser.org/oma/group/A0A8C2M0R8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5BJY9-1", "protein_name": "Keratin, type I cytoskeletal 18", "gene_name": "Krt18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSFTTRSTTFSTNYRSLGSVRTPSQRVRPASSAASVYAGAGGSGSRISVSRSVWGGSVGSAGLAGMGGVQTEKETMQDLNDRLASYLDKVKNLETENRRLESKIREYLEKRGPQGVRDWGHYFKTIEDLRAQIFANSVDNARIVLQIDNARLAADDFRVKYETELAMRQSVESDIHGLRKVVDDTNITRLQLETEIEALKEELLFMKKNHEEEVQGLEAQIASSGLTVEVDAPKSQDLSKIMADIRAQYEQLAQKNREELDKYWSQQIEESTTVVTTKSAEIRDAETTLLELRRTLQTLEIDLDSMKNQNINLENNLGEVEARYRVQMEQLNGVLLHLESELAQTRAEGQRQTQEYEALLNIKVKLEAEIATYRRLLEDGDDFSLNDALDSSNSMQTVQRTTTRKVVDGKVVSETNDTRVLRH", "length": 423 }, "evidence": [ { "id": "A0A8C2M0R8", "url": "https://omabrowser.org/oma/group/A0A8C2M0R8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7ZTS4-1", "protein_name": "Keratin, type I cytoskeletal 18", "gene_name": "krt18", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSLRTSYSVRSSTSQVPVSQVSIKRTTNVPTYRAASIYGGAGGQGTRISSASYSGVRSGLGVPSMSSSIQVSASGSTGEIMGNEKMAMQNLNDRLASYLEKVRILEQANSKLELKIREALEKRGPDVHDYSRFQPIVDELRKKIFDATTNNARLVLQIDNARLAADDFRVKYESELSIRQGVEADITGLRKVIDDTNLNRMNLESEIEALKEELIFLKKNHDNEVMELRNQISQSGVQVDVDAPKGQDLSQIMEEIRAKYEKMALKNQEELKAWHESQITEVQVQVTQNTEALQGARSEVNELRRQIQTLEIELESQKNLKGSLEGTLRDTEMRYNMEIENLNTIILQLEAELTQLRGNIQHQTQEYEALLNIKMKLEAEIATYRRLLDGGDFKLQDALEEQKKVKVMTVTQTLVDGKVVSSSTETKERKL", "length": 431 }, "evidence": [ { "id": "A0A8C2M0R8", "url": "https://omabrowser.org/oma/group/A0A8C2M0R8/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M0R8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0R8" } ], "pmid": "" } ] }, { "name": "Cellular 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This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. 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[], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M0Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0Y4" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M0Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0Y4" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100765542", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100765542", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2KB50-1", "protein_name": "Similar to human chromosome 1 open reading frame 87", "gene_name": "C5h1orf87", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSPWKTPPSSAPKPEMIVKIIGSKHFRYFVEKPMIRQNETLKTEPQTPLPEPGTDYSRQVRRDLPGPTDSSEQQISAHPAEKEESGQKPESNQKFLTTVLGNRFLDDMISHGANVHCSSVPAGDQSLSYMHSLPRRKSIDWCLENTKDNSGQAVEVVRRPSVMTREDSFLIALVRRELNSCPLSSNLLDKLQKELKTLDPISSGFLHQSQLNRLFLRHKVPLPLPTLKLLCQRFSRRDSPEGVNYGELLCFLKEATKDNLQQNGTAVYSNPRKTPSLSQDKQSTPPQDSSLLSDVNKSLLQILKMALRTYQGKFSVDCLNLNFQKEDHSFSGCLPLPKIMSICSKHGLHITMTLLETLLHHQDLGYRGEIKWKNFVKWLNRASSDLQYDMPAGKNKKEVQENLVNIPEGTQRNTEYVKTSEKNLQPKTSTTSAPEGPVTAFKYRPASEPGEHRAMMKDEQPELWIDRFRKLENALYLCDLSNTGVLEWERAKRLIHNYNLIYKLSLSPRRIDQALRRFRSGENIILEPALQYLKEL", "length": 537 }, "evidence": [ { "id": "A0A8C2M0Y4", "url": "https://omabrowser.org/oma/group/A0A8C2M0Y4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A2AGB2-1", "protein_name": "Uncharacterized protein C1orf87 homolog", "gene_name": "Gm12695", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSPWKTSQSSVPMPEMIVKIVGSKHFRYFIEKPMNKQNEKLKTEPQTSLQKPRNDYSRRVSRDLPGPTDSSEQQITANPAEKEESKHQRSSLKPESNQKFLTRVFSNRFLDGRISYEANVHCSSVPTGDQSLSYMHSLPRRKSVGWCLEHTAKDSSGQAEEIVQRPSVMTREDSFLTTLVRRELNSRPLSSNLLDKLQKELKTLDPISSGFLHQSQLSCLFLRHKVPLPLLTVKLLCQRFSRRCSPEMVNYGEVLCFLKEATKDNLQQNGTAGYSNSRKTSSPSYHKQSIPPQDSSLLSEVNKSLLEILKMALRPCQGKLSIDCLNMSFRKEDHSFSGCLPLPKVISICSKHGLYVTMTLLETLLHHQELGYRGEIKWKNFVKWLNRASADLSCDMPAGKNKKETQGDLVDIPERPQRKTEHVKTPEENLQTKNPTTMTSAPEDPVTFFKNRPVSQPVEHLAVKKDGQSELWIDRFRKLENALYLCDLSNTGVLERERARRLIHNYNLIYSLSLSPRRINQALQRYRSGENIILEPALQYLKEL", "length": 545 }, "evidence": [ { "id": "A0A8C2M0Y4", "url": "https://omabrowser.org/oma/group/A0A8C2M0Y4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N0U7-1", "protein_name": "Uncharacterized protein C1orf87", "gene_name": "C1orf87", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSAWKTPRGSDAMPEIMVKIIGSKHFQYLVEKPKIKENDSLKTETQTMHQKPMTDNARQMSRDTPVPINFTDQQTTDNPDDVKEKKHPENNQKSENNQKLLTGANSSRFLDGNIPSQANVHCSSVPTGDQSLSYVHGIPRRKLRDWSLEQMVRGSSDQPEDIGQSPSGTTNEDAFLLALVRRELKSRPLSSNLLEKLQKELKILDPISSGFLLQSQLSRLFLKHEVPLQLPTVKILCQRFSKRGSPEMVNYEKLLWFLNSAASDYPQQNKAAADLRKTESHGTHSQSTPPQHSSSQPEVNRSLLEILKMALRTTNGRLNIDNLNLSFRKEDRSFSGCLPLPKVRAICGKHGLYLTLSLLETLLNHQDLGYQNEIKWQNFVEMLTRASSDLLSDLPTGKNEKKAPAPPMEPEVPEMSQSKTEHMKTPEEELQPESSPAETSACKDPLKPLKIRPVSQPFVNPAVKNKAEECETWIDRFRKLENALYLCDLSNTGVLEKERARRLIHNYNLIYNLSLSPQKIDQALRRFRSGENMLLEPALRYLKEL", "length": 546 }, "evidence": [ { "id": "A0A8C2M0Y4", "url": "https://omabrowser.org/oma/group/A0A8C2M0Y4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M0Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0Y4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" }, { "start_pos": 328, "end_pos": 330, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2M0Y4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0Y4" }, { "id": "PF17743", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17743" }, { "id": "PF20742", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20742" }, { "id": "PF20743", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20743" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF5580", "eco_id": "ECO_0000259", "start_pos": 175, "end_pos": 267, "start_aa": "Asp", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 271, "end_pos": 273 }, { "start_pos": 304, "end_pos": 306 }, { "start_pos": 328, "end_pos": 330 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2M2Q2-1", "uniprot_ac": "A0A8C2M2Q2", "uniprot_id": "A0A8C2M2Q2_CRIGR", "mass": { "chemical_mass": 51218.0, "monoisotopic_mass": 51218.0 }, "refseq": { "ac": "XP_027283432", "name": "heterogeneous nuclear ribonucleoprotein H isoform X11", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283432" }, "gene_names": [ { "name": "Hnrnph1", "type": "recommended", "evidence": [ { "id": "A0A8C2M2Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2Q2" } ] }, { "name": "Hnrnph1", "type": "synonym", "evidence": [ { "id": "XP_027283432", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283432" } ] } ], "protein_names": [ { "name": "Heterogeneous nuclear ribonucleoprotein H isoform X11", "type": "synonym", "evidence": [ { "id": "A0A8C2M2Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2Q2/entry#names_and_taxonomy" } ] }, { "name": "heterogeneous nuclear ribonucleoprotein H isoform X11", "type": "synonym", "evidence": [ { "id": "XP_027283432", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283432" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027283432", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283432" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M2Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2Q2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Hnrnph1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2Q2", "locus": {} } ], "crossref": [ { "id": "cd12729", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12729", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12731", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12731", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12734", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12734", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100769493", "url": "https://www.ncbi.nlm.nih.gov/gene/100769493", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012996", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012996", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050666", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050666", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769493", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769493", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2M2Q2", "url": "https://www.orthodb.org/?gene=A0A8C2M2Q2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13976", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13976", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08080", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08080", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28441", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28441", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027283432", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027283432", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2M0Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0Z8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M0Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0Z8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M2Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2Q2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M2Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2Q2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDW2", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GDW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GDW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GEI0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GEI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEI0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GEI7", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GEI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GEI7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GG90", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GG90-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GG90-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GHZ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GHZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GHZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GIZ9", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7GIZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7GIZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQ24", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQ24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JQ24-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JQ24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JW14", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JW14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JW14-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JW14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JZD8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JZD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZD8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMLGAEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRRGAYGGGYGGYDDYNGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSTFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGASGGAYEHRYVELFLNSTAGASGGAYGSQMMGGMGLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGYGSQGAVNSSYYNSGSRASMGVNGMGGMSSMSSMSGGWGM", "length": 472, "header": "tr|A0A8C2M2Q2-1|A0A8C2M2Q2_CRIGR Isoform 1 of Heterogeneous nuclear ribonucleoprotein H isoform X11 OS=Cricetulus griseus OX=10029 GN=Hnrnph1 PE=4 SV=1 CANONICAL=A0A8C2M2Q2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2M0Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2Q2/entry#A0A8C2M0Z8-1", "sequence": { "sequence": "MMLGAEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRRGAYGGGYGGYDDYNGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSTFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGASGGAYEHRYVELFLNSTAGASGGAYGSQMMGGMGLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGYDQVLQENSSDFQSNIA", "length": 449, "header": "tr|A0A8C2M0Z8-1|A0A8C2M2Q2_CRIGR Computationally mapped isoform of Heterogeneous nuclear ribonucleoprotein H isoform X11 OS=Cricetulus griseus OX=10029 GN=Hnrnph1 PE=4 SV=1 CANONICAL=A0A8C2M2Q2-1" }, "locus": {} }, { "isoform_ac": "A0A8C2M2Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2Q2/entry#A0A8C2M2Q2-1", "sequence": { "sequence": "MMLGAEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRRGAYGGGYGGYDDYNGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSTFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGASGGAYEHRYVELFLNSTAGASGGAYGSQMMGGMGLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGYGSQGAVNSSYYNSGSRASMGVNGMGGMSSMSSMSGGWGM", "length": 472, "header": "tr|A0A8C2M2Q2-1|A0A8C2M2Q2_CRIGR Isoform 1 of Heterogeneous nuclear ribonucleoprotein H isoform X11 OS=Cricetulus griseus OX=10029 GN=Hnrnph1 PE=4 SV=1 CANONICAL=A0A8C2M2Q2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GDW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2Q2/entry#A0A9J7GDW2-1", "sequence": { "sequence": "MMLGAEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRRGAYGGGYGGYDDYNGYNDGYGFGSDRFGRGMSDHRYGDGGSTFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGASGGAYGSQMLGGMGLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGYGSQGAVNSSYYNSGSRASMGVNGMGGMSSMSSMSGGWGM", "length": 445, "header": "tr|A0A9J7GDW2-1|A0A9J7GDW2_CRIGR Computationally mapped isoform of Heterogeneous nuclear ribonucleoprotein H isoform X16 OS=Cricetulus griseus OX=10029 GN=Hnrnph1 PE=4 SV=1 CANONICAL=A0A8C2M2Q2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GEI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2Q2/entry#A0A9J7GEI0-1", "sequence": { "sequence": "MMLGAEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRRGAYGGGYGGYDDYNGYNDGYGFGSDRFGRGMSDHRYGDGGSTFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGASGGAYGSQMLGGMGLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGYDQVLQENSSDFQSNIA", "length": 422, "header": "tr|A0A9J7GEI0-1|A0A9J7GEI0_CRIGR Computationally mapped isoform of Heterogeneous nuclear ribonucleoprotein H isoform X20 OS=Cricetulus griseus OX=10029 GN=Hnrnph1 PE=4 SV=1 CANONICAL=A0A8C2M2Q2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GEI7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2Q2/entry#A0A9J7GEI7-1", "sequence": { "sequence": "MMLGAEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRRGAYGGGYGGYDDYNGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSTFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGASGGAYEHRYVELFLNSTAGASGGAYANQSSYGGPASQQLSGGYGGGYGGQSSMSGYDQVLQENSSDFQSNIA", "length": 439, "header": "tr|A0A9J7GEI7-1|A0A9J7GEI7_CRIGR Computationally mapped isoform of Heterogeneous nuclear ribonucleoprotein H isoform X18 OS=Cricetulus griseus OX=10029 GN=Hnrnph1 PE=4 SV=1 CANONICAL=A0A8C2M2Q2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GG90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2Q2/entry#A0A9J7GG90-1", "sequence": { "sequence": "MMLGAEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRRGAYGGGYGGYDDYNGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSTFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGASGGAYGSQMLGGMGLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGYGSQGAVNSSYYNSGSRASMGVNGMGGMSSMSSMSGGWGM", "length": 452, "header": "tr|A0A9J7GG90-1|A0A9J7GG90_CRIGR Computationally mapped isoform of Heterogeneous nuclear ribonucleoprotein H isoform X14 OS=Cricetulus griseus OX=10029 GN=Hnrnph1 PE=4 SV=1 CANONICAL=A0A8C2M2Q2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GHZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2Q2/entry#A0A9J7GHZ9-1", "sequence": { "sequence": "MMLGAEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRRGAYGGGYGGYDDYNGYNDGYGFGSDRFGRGMSDHRYGDGGSTFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGASGGAYEHRYVELFLNSTAGASGGAYGSQMMGGMGLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGYGSQGAVNSSYYNSGSRASMGVNGMGGMSSMSSMSGGWGM", "length": 465, "header": "tr|A0A9J7GHZ9-1|A0A9J7GHZ9_CRIGR Computationally mapped isoform of Heterogeneous nuclear ribonucleoprotein H isoform X12 OS=Cricetulus griseus OX=10029 GN=Hnrnph1 PE=4 SV=1 CANONICAL=A0A8C2M2Q2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7GIZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2Q2/entry#A0A9J7GIZ9-1", "sequence": { "sequence": "MMLGAEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRRGAYGGGYGGYDDYNGYNDGYGFGSDRFGRGMSDHRYGDGGSTFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGASGGAYEHRYVELFLNSTAGASGGAYGSQMMGGMGLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGYDQVLQENSSDFQSNIA", "length": 442, "header": "tr|A0A9J7GIZ9-1|A0A9J7GIZ9_CRIGR Computationally mapped isoform of Heterogeneous nuclear ribonucleoprotein H isoform X17 OS=Cricetulus griseus OX=10029 GN=Hnrnph1 PE=4 SV=1 CANONICAL=A0A8C2M2Q2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JQ24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2Q2/entry#A0A9J7JQ24-1", "sequence": { "sequence": "MAMQRPGPYDRPGAGRGYNSIGRGAGFERMRRGAYGGGYGGYDDYNGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSTFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGASGGAYEHRYVELFLNSTAGASGGAYGSQMMGGMGLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGYGSQGAVNSSYYNSGSRASMGVNGMGGMSSMSSMSGGWGM", "length": 271, "header": "tr|A0A9J7JQ24-1|A0A9J7JQ24_CRIGR Computationally mapped isoform of Heterogeneous nuclear ribonucleoprotein H isoform X21 OS=Cricetulus griseus OX=10029 GN=Hnrnph1 PE=4 SV=1 CANONICAL=A0A8C2M2Q2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JW14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2Q2/entry#A0A9J7JW14-1", "sequence": { "sequence": "MMLGAEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRRGAYGGGYGGYDDYNGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSTFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGASGGAYGSQMLGGMGLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGYDQVLQENSSDFQSNIA", "length": 429, "header": "tr|A0A9J7JW14-1|A0A9J7JW14_CRIGR Computationally mapped isoform of Heterogeneous nuclear ribonucleoprotein H isoform X19 OS=Cricetulus griseus OX=10029 GN=Hnrnph1 PE=4 SV=1 CANONICAL=A0A8C2M2Q2-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JZD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2Q2/entry#A0A9J7JZD8-1", "sequence": { "sequence": "MMLGAEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIRFIYTREGRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRRGAYGGGYGGYDDYNGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSTFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVEFATHEDAVAAMSKDKANMQHRYVELFLNSTAGASGGAYEHRYVELFLNSTAGASGGAYANQSSYGGPASQQLSGGYGGGYGGQSSMSGYGSQGAVNSSYYNSGSRASMGVNGMGGMSSMSSMSGGWGM", "length": 462, "header": "tr|A0A9J7JZD8-1|A0A9J7JZD8_CRIGR Computationally mapped isoform of Heterogeneous nuclear ribonucleoprotein H isoform X13 OS=Cricetulus griseus OX=10029 GN=Hnrnph1 PE=4 SV=1 CANONICAL=A0A8C2M2Q2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M0Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0Z8" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M0Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M0Z8" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100769493", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769493", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M2Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2Q2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M2Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2Q2" } ], "pmid": "" }, { "name": "ribonucleoprotein complex", "id": "GO:1990904", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990904", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M2Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2Q2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 362, "end_pos": 364, "annotation": "n_glycosylation_sequon" }, { "start_pos": 382, "end_pos": 384, "annotation": "n_glycosylation_sequon" }, { "start_pos": 404, "end_pos": 406, "annotation": "n_glycosylation_sequon" }, { "start_pos": 440, "end_pos": 442, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2M2Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2Q2" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 90, "start_aa": "Phe", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 362, "end_pos": 364 }, { "start_pos": 382, "end_pos": 384 }, { "start_pos": 404, "end_pos": 406 }, { "start_pos": 440, "end_pos": 442 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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Protocadherin beta-18 OS=Cricetulus griseus OX=10029 GN=LOC100774623 PE=4 SV=1 CANONICAL=A0A8C2M131-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M131", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M131" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"evidence": [ { "database": "UniProtKB", "id": "A0A8C2M131", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M131" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M131", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M131" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 418, "end_pos": 420, "annotation": "n_glycosylation_sequon" }, { "start_pos": 463, "end_pos": 465, "annotation": "n_glycosylation_sequon" }, { "start_pos": 567, "end_pos": 569, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2M131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M131" }, { "id": "PS50268", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50268" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cadherin", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 133, "start_aa": "Ser", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 169, "end_pos": 171 }, { "start_pos": 418, "end_pos": 420 }, { "start_pos": 463, "end_pos": 465 }, { "start_pos": 567, "end_pos": 569 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"yes" } }, { "uniprot_canonical_ac": "A0A8C2M152-1", "uniprot_ac": "A0A8C2M152", "uniprot_id": "A0A8C2M152_CRIGR", "mass": { "chemical_mass": 102076.0, "monoisotopic_mass": 102076.0 }, "refseq": { "ac": "XP_027256487", "name": "WD repeat-containing protein 36 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256487" }, "gene_names": [ { "name": "Wdr36", "type": "recommended", "evidence": [ { "id": "A0A8C2M152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M152" } ] }, { "name": "Wdr36", "type": "synonym", "evidence": [ { "id": "XP_027256487", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256487" } ] } ], "protein_names": [ { "name": "WD repeat-containing protein 36 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_027256487", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256487" }, { "id": "A0A8C2M152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M152/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048595.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027256487", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256487" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M152", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M152" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Wdr36", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M152", "locus": {} } ], "crossref": [ { "id": "100773715", "url": "https://www.ncbi.nlm.nih.gov/gene/100773715", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007319", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007319", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059157", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059157", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773715", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773715", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2M152", "url": "https://www.orthodb.org/?gene=A0A8C2M152", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22840", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22840", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22840:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22840:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04192", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04192", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25171", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25171", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027256487", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027256487", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2M152", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M152", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M152-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M152-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FGX6", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FGX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FGX6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRHAEAPGELFPPGRELSRIPAEAEMESAVEGRTASVLFAGFRALGLFSNDVPHVVRYSALKRRFYVTTCVGKSFHTYDVQKLSLVAVSNSVPQDICCMAADGRLVFAAYGKVFSAFARSKEIVHTFKGHKAEIHLLQPFGDHVISVDTDSILIIWHVYSEEEYLQLTFDKSVFQISTILHPSTYLNKILLGSEQGSLQLWNVKSNKLLYTFPGWKVGVTALQQAPAVDVVAIGLMSGQVVIHNIKFDETLMKFRQDWGPITSISFRTDGHPVMAAGSPCGHIGLWDLEDKKLINQMRNAHSTAIAGLTFLHREPLLVTNGADNALRIWIFDGPTGEGRLLRFRMGHSASLTKIRYYGQNGQQILSASQDGTLQSFSTVHEKFNKSLGHGLINKKIVKRKGLQNTMSVRLPPITKFAAEEARQSDWDGIIACHQGKLSCSTWNYQRSTIGAYFLKPKELKTDDIIATAVDITSCGNFAVIGLSSGTVDVYNMQSGIHRGSFGDDKAHAGSVRGVAVDGLNQLTVTAGSERLLKFWNFKSKVLIHSLSLDSSPNMMLLHRDSGILGLALDDFSITVLDIETRKIVREFSGHQGQINDMTFSPDGRWLISAAMDCSIRTWDLPSGCLIDCFLLDSAPLNITMSPTGDFLATSHVDHLGIYLWSNISLYSVVSLRPLPPDYVPSVVMLPGTCQTQGTEVLEEQIEPSDEMIEYESPEQLSEQLVTLSLLPESRWKNLLNLDVIKKKNKPKEPPKVPQSAPFFIPTVPGLVPRFAVPEQNGDPQQSKVVNLGILAQKSNFYLKLEEGLLNNQYEAALNLLKELGPSGIETELRNLSPDDGGSVKVMQGFLKMIGMMLNRKRDFELAQAYLALFLKLHLKMLPSEPVLLEELVKLSSQVEEDWTHLQSLFNQSMCVLNYIKSALL", "length": 920, "header": "tr|A0A8C2M152-1|A0A8C2M152_CRIGR Isoform 1 of WD repeat-containing protein 36 isoform X3 OS=Cricetulus griseus OX=10029 GN=Wdr36 PE=4 SV=1 CANONICAL=A0A8C2M152-1" }, "isoforms": [ { "isoform_ac": "A0A8C2M152-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M152/entry#A0A8C2M152-1", "sequence": { "sequence": 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repeat-containing protein 36 isoform X3 OS=Cricetulus griseus OX=10029 GN=Wdr36 PE=4 SV=1 CANONICAL=A0A8C2M152-1" }, "locus": {} }, { "isoform_ac": "A0A9J7FGX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M152/entry#A0A9J7FGX6-1", "sequence": { "sequence": "MRHAEAPGELFPPGRELSRIPAEAEMESAVEGRTASVLFAGFRALGLFSNDVPHVVRYSALKRRFYVTTCVGKSFHTYDVQKLSLVAVSNSVPQDICCMAADGRLVFAAYGKVFSAFARSKEIVHTFKGHKAEIHLLQPFGDHVISVDTDSILIIWHVYSEEEYLQLTFDKSVFQISTILHPSTYLNKILLGSEQGSLQLWNVKSNKLLYTFPGWKVGVTALQQAPAVDVVAIGLMSGQVVIHNIKFDETLMKFRQDWGPITSISFRTDGHPVMAAGSPCGHIGLWDLEDKKLINQMRNAHSTAIAGLTFLHREPLLVTNGADNALRIWIFDGPTGEGRLLRFRMGHSASLTKIRYYGQNGQQILSASQDGTLQSFSTVHEKFNKSLGHGLINKKIVKRKGLQNTMSVRLPPITKFAAEEARQSDWDGIIACHQGKLSCSTWNYQRSTIGAYFLKPKELKTDDIIATAVDITSCGNFAVIGLSSGTVDVYNMQSGIHRGSFGDDKAHAGSVRGVAVDGLNQLTVTAGSERLLKFWNFKSKVLIHSLSLDSSPNMMLLHRDSGILGLALDDFSITVLDIETRKIVREFSGHQGQINDMTFSPDGRWLISAAMDCSIRTWDLPSGCLIDCFLLDSAPLNITMSPTGDFLATSHVDHLGIYLWSNISLYSVVSLRPLPPDYVPSVVMLPGTCQTQEVLEEQIEPSDEMIEYESPEQLSEQLVTLSLLPESRWKNLLNLDVIKKKNKPKEPPKVPQSAPFFIPTVPGLVPRFAVPEQNGDPQQSKVVNLGILAQKSNFYLKLEEGLLNNQYEAALNLLKELGPSGIETELRNLSPDDGGSVKVMQGFLKMIGMMLNRKRDFELAQAYLALFLKLHLKMLPSEPVLLEELVKLSSQVEEDWTHLQSLFNQSMCVLNYIKSALL", "length": 918, "header": "tr|A0A9J7FGX6-1|A0A9J7FGX6_CRIGR Computationally mapped isoform of WD repeat-containing protein 36 isoform X4 OS=Cricetulus griseus OX=10029 GN=Wdr36 PE=4 SV=1 CANONICAL=A0A8C2M152-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M152", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M152" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M152", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M152" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100773715", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773715", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Pwp2p-containing subcomplex of 90S preribosome", "id": "GO:0034388", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034388", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M152", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M152" } ], "pmid": "" }, { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M152", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M152" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M152", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M152" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 637, "end_pos": 639, "annotation": "n_glycosylation_sequon" }, { "start_pos": 662, "end_pos": 664, "annotation": "n_glycosylation_sequon" }, { "start_pos": 830, "end_pos": 832, "annotation": "n_glycosylation_sequon" }, { "start_pos": 906, "end_pos": 908, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], 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"tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2M154-1", "uniprot_ac": "A0A8C2M154", "uniprot_id": "A0A8C2M154_CRIGR", "mass": { "chemical_mass": 224690.0, "monoisotopic_mass": 224690.0 }, "refseq": { "ac": "XP_003501190", "name": "fer-1-like protein 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501190" }, "gene_names": [ { "name": "Fer1l4", "type": "recommended", "evidence": [ { "id": "A0A8C2M154", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M154" } ] }, { "name": "Fer1l4", "type": "synonym", "evidence": [ { "id": "XP_003501190", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501190" } ] } ], "protein_names": [ { "name": "Fer-1-like protein 4 isoform X3", "type": "synonym", "evidence": [ { "id": "A0A8C2M154", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M154/entry#names_and_taxonomy" } ] }, { "name": "fer-1-like protein 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003501190", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501190" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613833.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003501190", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501190" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M154", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M154" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Fer1l4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M154", "locus": {} } ], "crossref": [ { "id": "cd04011", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04011", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04017", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04017", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04037", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04037", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08373", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08373", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08374", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08374", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100755848", "url": "https://www.ncbi.nlm.nih.gov/gene/100755848", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012561", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012561", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012968", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012968", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032362", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032362", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037720", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037720", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037721", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037721", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037723", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037723", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037724", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037724", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037726", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037726", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100755848", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755848", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DHTWRLC", "url": "https://omabrowser.org/oma/group/DHTWRLC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2M154", "url": "https://www.orthodb.org/?gene=A0A8C2M154", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12546", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12546", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12546:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12546:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08150", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08150", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08151", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08151", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16165", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16165", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22901", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22901", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003501190", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501190", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2M154", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M154", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M154-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M154-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1F1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1F1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7H1F1-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7H1F1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALTVCVRRLTELPGIHDRQVKLCFRGFTQKTRKIHCGREADVGEMFRWPHYGSPLAGESLTVQVVNCSRVFSPRSLGTLVISLQQLQSSGHLVLREALVDEKLRVSPIQVELDLKYQPPEGAAGTWVEEDFGTPIRDSSELIIPNVGFQEMEPGEARLERQAVALGRRLARSLGTQDDEENELELELELEDEPDVEISGVVFSPLKSRTLGLPRRDPFQVCRAQDFQVGVTILEAQKLVGVNINPYVAVRVGDQRRVTATQRGTNCPFYNEYFLFEFHKTRLHLQELLIEITVFHSQTLPFMATRVGTFRMDLGMALDQPDGHFHQKWAPLHDPCDTRSGTKGFVKITLSVRARGDLPLPLPAPIPGTSSDIEKNLLLPRGVQAERPWARLRVRVYRAEGLPTVRTGLLGSLARALHDQHVLLDPYVRVSFLGQQGETSVCEEETEPEWNEQLSFVELFPPLTRGLRLQLREDAPLLDVALATHVLDLRQISNSGRTAGFNPTFGPAWVPLYGSLPSGRFRDGLQSLNEGVGEGIWFRGRILVAVSMEVLEGRVEPTSPQSTQGSRLSRLTGKKKKKTKQRQTTAGVPKPVDASASGDAPEIPSAMEVEVEELLPLPENALAPCEDFLLFAVVFEATMIDPSLAKQPISLEISIGHTGRREEQLGQRSRADEGAEGSTLESESRPLLGSEDRGAGQEEEELLGTPDQWPEPVDGNGPYLCLPLLHQKPCLHVWSRWEDYTWRLHSSNSVYKVAERLDQGLQEVEKIQRRSGLGACTRLKQTLEELVAGSRQFCLGAERRTMTRPNTLDRCRGKLLSHSLNLMAKQGLQLLRGLRQSNMQRKVALAKKLLAKLHFLAKEPQPPFPDVLVWMISGQRRVAYARVPAQDVLFSVVEEERGRDCGKIQSLLLTAPGAAPGEVCAKLELFLWLGLAKQAKACTSELPPDLLPEPSAGLPHSLYRDDFSYFQLRAHLYQARGVLAADDSGLSDPFAHVLISTQCQTTRVLEQTLSPLWDELLVFEQLIVDGRREHLQEEPPLVVINVFDHNKFGPAVFLGRALAAPRVKLIEDPYQRPELQFFPLRKGSQAAGEVIATFELIELDYRGHLEPTVPSDVEPQDLASLVQPITGHLSLPPNVRPVLREFRIEVLFWGLRGLGRIHLFEVERPQVVLEVAGRRVESEVLASYRESPNFTELVQHVTVDLPEQPYLQPPLSILVIENRAFGRTVLVGSHIVPHMLRFTLQGHEDPPEEEEIEEDTRDLTPKGPQGEQSGDPFVAKAGQSSRLLKAPLKKLTLGLLGQGPELEEDIPDPEEMDWWSKYYASLQELQGQSGFDEDEMEDAGDPDGTHLISGDREAQEQGRTDIKVSGPQKKAIATLKIYNSSLEEEFNHFEDWLNVFPLYRGQGGQAGDGEEGSGHLVGKFKGSFLIYPESEAASFSEPQISRGIPQNRPIKLLVRVYVVKATNLAPADPNGKADPYVVVSAGKEQRDTKERYIPKQLHPIFGEVLELSVSLPAEPELTVAIFDHDLVGSDDLIGETRIDLENRFYSHHRANCGLASQYDVDGYNAWRDAFRPSQILLGLCQRCGLPAPEYRAGAVKVGTRVFLTPSEALPSDGRDPKGTNEASEEAQALLVLRRWQEMPGFGIQLVPEHVETRPLYHPRSPGLLQGSLHMWIDIFPSDVPAPPPVDIKPRQPISYELRVVIWNTEDVVLDDVNPLTGEMSSDIYVKSWVKGLEHDKQETDVHFNSLTGEGNFNWRFVFRFDYLPTEREVSVRRKPGPFALEEAEFRQPAVLALQVWDFDRISANDFLGSLELQLPDMVRGARVPEQCSVRLALDGAGPRCNLFRCRRLRGWWPVVKTREMEDVEREAREAQAGKKRKRRRRRKGRPEDLEFTDTGGNVYILTGKVEAEFELLTVEEAEKRPVGKGRKEPEPLEKPNRPKTSFNWFVNPLKTFVFFIWRRYWRILVLLLLLALITVFLLLVFYTIPGQISEVIFSPIHKH", "length": 1999, "header": "tr|A0A8C2M154-1|A0A8C2M154_CRIGR Isoform 1 of Fer-1-like protein 4 isoform X3 OS=Cricetulus griseus OX=10029 GN=Fer1l4 PE=4 SV=1 CANONICAL=A0A8C2M154-1" }, "isoforms": [ { "isoform_ac": "A0A8C2M154-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M154/entry#A0A8C2M154-1", "sequence": { "sequence": "MALTVCVRRLTELPGIHDRQVKLCFRGFTQKTRKIHCGREADVGEMFRWPHYGSPLAGESLTVQVVNCSRVFSPRSLGTLVISLQQLQSSGHLVLREALVDEKLRVSPIQVELDLKYQPPEGAAGTWVEEDFGTPIRDSSELIIPNVGFQEMEPGEARLERQAVALGRRLARSLGTQDDEENELELELELEDEPDVEISGVVFSPLKSRTLGLPRRDPFQVCRAQDFQVGVTILEAQKLVGVNINPYVAVRVGDQRRVTATQRGTNCPFYNEYFLFEFHKTRLHLQELLIEITVFHSQTLPFMATRVGTFRMDLGMALDQPDGHFHQKWAPLHDPCDTRSGTKGFVKITLSVRARGDLPLPLPAPIPGTSSDIEKNLLLPRGVQAERPWARLRVRVYRAEGLPTVRTGLLGSLARALHDQHVLLDPYVRVSFLGQQGETSVCEEETEPEWNEQLSFVELFPPLTRGLRLQLREDAPLLDVALATHVLDLRQISNSGRTAGFNPTFGPAWVPLYGSLPSGRFRDGLQSLNEGVGEGIWFRGRILVAVSMEVLEGRVEPTSPQSTQGSRLSRLTGKKKKKTKQRQTTAGVPKPVDASASGDAPEIPSAMEVEVEELLPLPENALAPCEDFLLFAVVFEATMIDPSLAKQPISLEISIGHTGRREEQLGQRSRADEGAEGSTLESESRPLLGSEDRGAGQEEEELLGTPDQWPEPVDGNGPYLCLPLLHQKPCLHVWSRWEDYTWRLHSSNSVYKVAERLDQGLQEVEKIQRRSGLGACTRLKQTLEELVAGSRQFCLGAERRTMTRPNTLDRCRGKLLSHSLNLMAKQGLQLLRGLRQSNMQRKVALAKKLLAKLHFLAKEPQPPFPDVLVWMISGQRRVAYARVPAQDVLFSVVEEERGRDCGKIQSLLLTAPGAAPGEVCAKLELFLWLGLAKQAKACTSELPPDLLPEPSAGLPHSLYRDDFSYFQLRAHLYQARGVLAADDSGLSDPFAHVLISTQCQTTRVLEQTLSPLWDELLVFEQLIVDGRREHLQEEPPLVVINVFDHNKFGPAVFLGRALAAPRVKLIEDPYQRPELQFFPLRKGSQAAGEVIATFELIELDYRGHLEPTVPSDVEPQDLASLVQPITGHLSLPPNVRPVLREFRIEVLFWGLRGLGRIHLFEVERPQVVLEVAGRRVESEVLASYRESPNFTELVQHVTVDLPEQPYLQPPLSILVIENRAFGRTVLVGSHIVPHMLRFTLQGHEDPPEEEEIEEDTRDLTPKGPQGEQSGDPFVAKAGQSSRLLKAPLKKLTLGLLGQGPELEEDIPDPEEMDWWSKYYASLQELQGQSGFDEDEMEDAGDPDGTHLISGDREAQEQGRTDIKVSGPQKKAIATLKIYNSSLEEEFNHFEDWLNVFPLYRGQGGQAGDGEEGSGHLVGKFKGSFLIYPESEAASFSEPQISRGIPQNRPIKLLVRVYVVKATNLAPADPNGKADPYVVVSAGKEQRDTKERYIPKQLHPIFGEVLELSVSLPAEPELTVAIFDHDLVGSDDLIGETRIDLENRFYSHHRANCGLASQYDVDGYNAWRDAFRPSQILLGLCQRCGLPAPEYRAGAVKVGTRVFLTPSEALPSDGRDPKGTNEASEEAQALLVLRRWQEMPGFGIQLVPEHVETRPLYHPRSPGLLQGSLHMWIDIFPSDVPAPPPVDIKPRQPISYELRVVIWNTEDVVLDDVNPLTGEMSSDIYVKSWVKGLEHDKQETDVHFNSLTGEGNFNWRFVFRFDYLPTEREVSVRRKPGPFALEEAEFRQPAVLALQVWDFDRISANDFLGSLELQLPDMVRGARVPEQCSVRLALDGAGPRCNLFRCRRLRGWWPVVKTREMEDVEREAREAQAGKKRKRRRRRKGRPEDLEFTDTGGNVYILTGKVEAEFELLTVEEAEKRPVGKGRKEPEPLEKPNRPKTSFNWFVNPLKTFVFFIWRRYWRILVLLLLLALITVFLLLVFYTIPGQISEVIFSPIHKH", "length": 1999, "header": "tr|A0A8C2M154-1|A0A8C2M154_CRIGR Isoform 1 of Fer-1-like protein 4 isoform X3 OS=Cricetulus griseus OX=10029 GN=Fer1l4 PE=4 SV=1 CANONICAL=A0A8C2M154-1" }, "locus": {} }, { "isoform_ac": "A0A9J7H1F1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M154/entry#A0A9J7H1F1-1", "sequence": { "sequence": "MALTVCVRRLTELPGIHDRQVKLCFRGFTQKTRKIHCGREADVGEMFRWPHYGSPLAGESLTVQVVNCSRVFSPRSLGTLVISLQQLQSSGHLVLREALVDEKLRVSPIQVELDLKYQPPEGAAGTWVEEDFGTPIRDSSELIIPNVGFQEMEPGEARLERQAVALGRRLARSLGTQDDEENELELELELEDEPDVEISGVVFSPLKSRTLGLPRRDPFQVCRAQDFQVGVTILEAQKLVGVNINPYVAVRVGDQRRVTATQRGTNCPFYNEYFLFEFHKTRLHLQELLIEITVFHSQTLPFMATRVGTFRMDLGMALDQPDGHFHQKWAPLHDPCDTRSGTKGFVKITLSVRARGDLPLPLPAPIPGTSSDIEKNLLLPRGVQAERPWARLRVRVYRAEGLPTVRTGLLGSLARALHDQHVLLDPYVRVSFLGQQGETSVCEEETEPEWNEQLSFVELFPPLTRGLRLQLREDAPLLDVALATHVLDLRQISNSGRTAGFNPTFGPAWVPLYGSLPSGRFRDGLQSLNEGVGEGIWFRGRILVAVSMEVLEGRVEPTSPQSTQGSRLSRLTGKKKKKTKQRQTTAGVPKPVDASASGDAPEIPSAMEVEVEELLPLPENALAPCEDFLLFAVVFEATMIDPSLAKQPISLEISIGHTGRREEQLGQRSRADEGAEGSTLESESRPLLGSEDRGAGQEEEELLGTPDQWPEPVDGNGPYLCLPLLHQKPCLHVWSRWEDYTWRLHSSNSVYKVAERLDQGLQEVEKIQRRSGLGACTRLKQTLEELVAGSRQFCLGAERRTMTRPNTLDRCRGKLLSHSLNLMAKQGLQLLRGLRQSNMQRKVALAKKLLAKLHFLAKEPQPPFPDVLVWMISGQRRVAYARVPAQDVLFSVVEEERGRDCGKIQSLLLTAPGAAPGEVCAKLELFLWLGLAKQAKACTSELPPDLLPEPSAGLPHSLYRDDFSYFQLRAHLYQARGVLAADDSGLSDPFAHVLISTQCQTTRVLEQTLSPLWDELLVFEQLIVDGRREHLQEEPPLVVINVFDHNKFGPAVFLGRALAAPRVKLIEDPYQRPELQFFPLRKGSQAAGEVIATFELIELDYRGHLEPTVPSDVEPQDLASLVQPITGHLSLPPNVRPVLREFRIEVLFWGLRGLGRIHLFEVERPQVVLEVAGRRVESEVLASYRESPNFTELVQHVTVDLPEQPYLQPPLSILVIENRAFGRTVLVGSHIVPHMLRFTLQGHEDPPEEEEIEEDTRDLTPKGPQGEQSGDPFVAKAGQSSRLLKAPLKKLTLGLLGQGPELEEDIPDPEEMDWWSKYYASLQELQGQSGFDEDEMEDAGDPDGTHLISGDREAQEQGRTDIKVSGPQKKAIATLKIYNSSLEEEFNHFEDWLNVFPLYRGQGGQAGDGEEGSGHLVGKFKGSFLIYPESEAASFSEPQISRGIPQNRPIKLLVRVYVVKATNLAPADPNGKADPYVVVSAGKEQRDTKERYIPKQLHPIFGEVLELSVSLPAEPELTVAIFDHDLVGSDDLIGETRIDLENRFYSHHRANCGLASQYDVDGYNAWRDAFRPSQILLGLCQRCGLPAPEYRAGAVKVGTRVFLTPSEALPSDGRDPKGTNEASEEAQALLVLRRWQEMPGFGIQLVPEHVETRPLYHPRSPGLLQGSLHMWIDIFPSDVPAPPPVDIKPRQPISYELRVVIWNTEDVVLDDVNPLTGEMSSDIYVKSWVKGLEHDKQETDVHFNSLTGEGNFNWRFVFRFDYLPTEREDPSSCSYQTW", "length": 1778, "header": "tr|A0A9J7H1F1-1|A0A9J7H1F1_CRIGR Computationally mapped isoform of Fer-1-like protein 4 isoform X4 OS=Cricetulus griseus OX=10029 GN=Fer1l4 PE=4 SV=1 CANONICAL=A0A8C2M154-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M154", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M154" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M154", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M154" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100755848", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100755848", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A3KGK3-1", "protein_name": "Fer-1-like protein 4", "gene_name": "Fer1l4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALTVCVRHLTGLPGTHDRQVRLCFRGFTQKTRKIHCGREADVGELFRWPHYGSPLAGESLSVQVVNCSRVFSPRPLGTLVISLQQLQSAGHLVLREALVDERLRVSPIQVELDLKYQPPEGAAGTWAEEDFGTPIRDSLELIIPNVGFQDMEPGEAQLERRAVALGRRLARSLGTQDDEENELELEPELEEEPDVEISGVVFSPLKSRALGLPRGDPFKVCKAQDFQVGVTVLEAQKLVGVNINPYVAVRVGDQRKVTATLRGTNCPFYNEYFLFEFHETRLHLQDLLLEITAFHSQTLPFMATRIGTFRMDLGMALDQPDGHFHQKWAPLHDPRDTRAGTKGFVKITLSVRARGDLPLPPPPPCPGTSSDIEKNLLLPHGVQAERPWARLRVRVYRAEGLPTVRTGLLGSLARALHDQNVLLDPYVRVSFLGQQGETSVRGEETAPKWNEQLSFVELFPPLTRSLRLQLRDNAPLVDVALATHVLDLRQISNSGRAAGFNPTFGPAWVPLYGSLPSGRLRDDLQSLNEGLGEGIWFRGRLLVAVSMEVYEGRVEPKPSQTTQRSGLSRLTGKKKKKKEKTRQGQTPAGILQPASASTSEDAPEIPSAMEVEVEDLLPLPENALASFEDFLLFGVLFEATMIDPSLAKKPISLEISIGHAGRQEEQSGQGSRADEGSESSTLEVQPLLESEDRGAGQEEQELLGTPAQWPEPVDGNGPYLCLPLRHRKPCLHVWSCWEDYTWRLQSSNSVCKVAERLDHGLQEVEKMQRRSGPGACTRLKQTLEELVAGSRQFCHGAERRTMTRPNALDRCRAKLLTHSLNLMARQGLRLLRSLRLNNMQRTVVLAKKLLARLRFLAQEPQPPLPDVLVWMFSGQRRVAYARIPAQDILYSVVEEERGRDCGKIQSLLLTVPGAAPGEVCAKLELFLWLGLGKQAKACTSELPMDLLPEPSSGLPQSLYRDDFRYFQLRAHLYQARGVLAADDSGLSDPFARVLISTQCQTTRVLEQTLSPLWDELLVFDQLIVDGRREHLREEPPLVVINVFDHNKFGPAVFLGRAFAAPRVKLIEDPYQRPELQFFPLRKGPQAAGEVIATFELIELDYSGHLEPSVPSDVEPRDLASLVEPISGHLSLPPSVRPVLRAFRVEVLFWGLRGLGRVHLFEIEKPQVVLEVAGRRVESEVLPNYRENPNFTELVRHVTVDLPEQPYLQPPLSILVIERRAFGRTVLVGSHIVPHMLRFILQGHEDPQEEEETEEETRDLVPHGPQGEKSLPEAGTSRQLLKAPLKKLTLGLLGQGPELEEDIPDPEEMDWWSKYYASLQEFQGQPSSDDEMDEAGDADGTHLISGDREAQEQGETDSKVSVPRKKAIATLKIYNSSLEDEFSHFEDWLSVFPLYRGQGGQDGEGEGASGHFVGKFKGSFLIYPESEAKSFSEPQISRGVPQNRPIKLLVRVYIVKATNLAPADPNGKADPYVVVSAGKEQRDTKERYIPKQLNPIFGEVLELSVSLPAQPELTVAVFDHDLVGSDDLIGETHIDLENRFYSHHRANCGLASQYDVNGYNAWRDAFRPSQILAGLCQRCGLPVPEYRAGAVKVGSRVFLTPSEAPPPDDRKPKVTSEASEEAQALHVLRRWQEMPGLGIQLVPEHVETRPLYHPRSPGLLQGSLHMWIDIFPSDVPAPPPVDIKPRQPISYELRVVIWNTDDVALDDVNPLTGERSSDIYVKSWVKGLEQDRQETDVHFNSLTGEGNFNWRFVFRFDYLPTEREVSVRRKPGPFALEEAEFRQPAVLVLQVWDYDRISANDFLGSLELQLPDMVRGARDPEHCSVRLALDGAGPRCNLFRCHRLRGWWPVVKMKDMEDVEREAREAQAGKKRKRKRRAGRPEDLEFTDTGGNVYILTGKVEAEFELLTVEEAEKRPVGKGRKEPEPLEKPNRPKTSFNWFVNPLKTFIFFIWRRYWRILVLLLLALITIFLLLVFYTIPGQISEVIFSPVHK", "length": 1992 }, "evidence": [ { "id": "A0A8C2M154", "url": "https://omabrowser.org/oma/group/A0A8C2M154/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4ABP2-1", "protein_name": "Fer-1-like family member 4", "gene_name": "Fer1l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALTVCVRHLTGLPGIHDRQVRLCFRGFTQKTRKIHCGREADVGELFRWPHYGSPLAGESLSVQVVNCSRVFSPRPLGTLVISLQRLQNTGHLVLREALVDERLRVSPIQVELDLKYQPPEGAAGTWAEEDFGAPIRDSLELIIPNVGFQDMEPGEAQLERRAVAMGRRLAQSLGTQDDEENELELELDLEEPDVEISGVVFSPLKSRALGLPRRDPFKACKAQDFQVGVTVLEAQKLVGVNINPYVTVRVGDQRRVTATQRGTNCPFYNEYFLFEFHETRLHLQDLLLEITAFHSQTLPFMATRIGTFRMDLGMALDQPDGHFHQKWAPLHDPRDTRAGTKGFIKITLSVRARGDLPLPPPPSTPGTSADIEKNLLLPRGVQAERPWARLRVRVYRAEGLPTVRTGLLGSLARALHDQHVLLDPYVRVSFLGQQGETSVRGEETAPEWNEQLSFVELFPPLTRSLRLQLRDDAPLADVALATHMLDLRQISNSGRAAGFNPTFGPAWVPLYGSLPSGRFRDGLQGLNEGLGEGIWFRGRLLVAVSMEVFEGRVEPKSSQTTQGSGLSRLTGKKKKKKEKTKQGQTPAGTLQPANASTEVGVPEIPSSMEVDMEELLPLPENALAPCEDFLLFGVLFEATMIDPSLAKKPISLEISIGHAGRREEQLGPGSRADGGSEGSTLEAQPLLESEDRGAGQEEQELLGTPAQWPEPVEGNGPYLCLPLRHRKPCLHVWSRWEDYTWRLHSSNSVCKVAERLDHGLQEVEKIQRRSVLGACTRLKQTLEELVAGSRQFCHGAERRTMTRPNALDRCRAKLLTHSLNLMARQGLRLLRSLRQNNIQRTVALAKKLLAKLHFLAQEPQPPLPDVLVWMFSGQRRVAYARVPAQDVLFSVVEEERGRDCGKIQSLLLTAPGAAPGEVCAKLELFLWLGLGKQSKACPSELPPDLLPEPSRGLPHSLYRDDFSYFQMRAHLYQARGVLAADDSGLSDPFARVLISTQCKTTRVLEQTLSPLWDELLVFDQLIVDGKREHLREEPPLVVINVFDHNKFGSAVFLGRAFAAPRVKLIEDSYQRPELQFFPLRKGPQAAGEVIATFELIELDYSGHLEPSVPSDVEPQDLASLVEPISGHLSLPASVRPVLREFRVEVLFWGLRGLGRVHLFEVEKPQVVLEVAGRRVESEVLANYCENPNFTELVQCVTVDLPEQPYLQPPLSILVIERRAFGRTVLVGSHIVPHMLRFTLQGQEDPREEERTEEETRGLVPQGLQGEKSLAEAGISRQRLKAPLKKLTLGLLGQGPELEEAIPDPQEMDWWSKYYASLQELQGQSSSDDDEMDDARDPDGTHLISGEREAQEQGETDIKVSVPRKKAIATLKIYHSSLEDEFNHFEDWLSVFPLYRGQGGQEGDGEEASGHFVGKFKGSFLIYPESEAKSFSEPQISRGIPQNRPIKLLVRVYIVKATNLAPADPNGKADPYVVVSAGKEQRDTKERYIPKQLNPIFGEVLELSVSLPAEPELTVAIFDHDLVGSDDLIGETHIDLENRFYSHHRANCGLASQYDVDGYNAWRDAFRPSQILAGLCQRCGLPIPEYRAGAVKVGSRVFLTPSEALPPDGRDPKGANEASEEAQALLVLRRWQEMPGLGIQLVPEHVETRPLYHPRSPGLLQGSLHMWIDVFPSDVPAPPPVDIKPRQPISYELRVVIWNTDDVVLDDVNPLTGEMSSDIYVKSWVKGLEHDRQETDVHFNSLTGEGNFNWRFVFRFDYLPTEREVSIRRKPGPFALEEAEFRQPAVLVLQVWDYDRVSANDFLGSLELQLPDMVRGARDPEHCTVRLALDGAGPRCNLFRCRRLRGWWPVVKTKDMEDVEREAREAQAGKKRKRKRRKGWPEDLEFTDTGGNVYILTGKVEAEFELLTVEEAEKRPVGKGRKEPEPLEKPNRPKTSFNWFVNPLKTFVFFILRRYWRILVVLLLLALITIFLLLVFYTIPGQISEVIFSPINKH", "length": 1994 }, "evidence": [ { "id": "A0A8C2M154", "url": "https://omabrowser.org/oma/group/A0A8C2M154/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "plasma membrane organization", "id": "GO:0007009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007009", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M154", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M154" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M154", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M154" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M154", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M154" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1189, "end_pos": 1191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1379, "end_pos": 1381, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2M154", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M154" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 97, "start_aa": "Met", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1189, "end_pos": 1191 }, { "start_pos": 1379, "end_pos": 1381 }, { "start_pos": 67, "end_pos": 69 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": 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"sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2M247-1", "uniprot_ac": "A0A8C2M247", "uniprot_id": "A0A8C2M247_CRIGR", "mass": { "chemical_mass": 65590.0, "monoisotopic_mass": 65590.0 }, "refseq": { "ac": "XP_003500669", "name": "uncharacterized protein C1orf94 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500669" }, "gene_names": [ { "name": "CUNH1orf94", "type": "recommended", "evidence": [ { "id": "A0A8C2M247", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M247" } ] }, { "name": "CUNH1orf94", "type": "synonym", "evidence": [ { "id": "XP_003500669", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500669" } ] } ], "protein_names": [ { "name": "Uncharacterized protein C1orf94 homolog", "type": "synonym", "evidence": [ { "id": "A0A8C2M247", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M247/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C1orf94 homolog", "type": "synonym", "evidence": [ { "id": "XP_003500669", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500669" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613801.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003500669", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500669" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M247", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M247" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "CUNH1orf94", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M247", "locus": {} } ], "crossref": [ { "id": "100773118", "url": "https://www.ncbi.nlm.nih.gov/gene/100773118", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100773118", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100773118", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KKPAWPA", "url": "https://omabrowser.org/oma/group/KKPAWPA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2M247", "url": "https://www.orthodb.org/?gene=A0A8C2M247", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35674", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35674", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35674:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35674:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15752", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15752", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003500669", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003500669", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2M247", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M247", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M247-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M247-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRAGGGQSLCLPALGGQRGFRKERKRMASGNGLPPSSAMVAKRPSALGPFPRYVWIHQDTPQDSLDKICHDIWKRVQGLPESLQPRTSLEKLSAPMTATVSFQEEALELSGGKDEISLLVEQEFLSLTKEHLILVQESSGELATPIVTPQGTRELAPCFLVPPLGADSTEYPGSSVTAGDKLREQKLSVPIISSRQDCDSAMSTVTGILRAAKVKSVKGTKDKSHSLSASNSEISKLLAQFPLKSTEMSKAPDNKMVLEETKVIKDFLQNSMFNGSGPREPMGLGPFLLLPPPPPPAPPDKLPEFSPPKRQLPVFAKICSKNEADSTLDGHHWIERTPGSKELTKGRESLFISQWPQSRKDTCGEEGHNDSIGTISMTLPTKKPVWPAEKNLLYEFFGATKNPSGQLRLRSKVDMDGLDLKFNPPALMPDKNNIKYAGNVFAPRFTTALTSTTLNQPLWLNLNCPPPPVFSNHSTFPQYQGLYPQRSTRMPYQQPVHPPMGCYSRQVTPYNPQQMGQQIFRSSYTPLMSYIPLVQPNYPYPQRTPQKLPANPRDPTPMAGDGPPYLFPQGYGFNSASSGPLMNSPYFSSSGNGIRF", "length": 596, "header": "tr|A0A8C2M247-1|A0A8C2M247_CRIGR Isoform 1 of Uncharacterized protein C1orf94 homolog OS=Cricetulus griseus OX=10029 GN=CUNH1orf94 PE=4 SV=1 CANONICAL=A0A8C2M247-1" }, "isoforms": [ { "isoform_ac": "A0A8C2M247-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M247/entry#A0A8C2M247-1", "sequence": { "sequence": "MRAGGGQSLCLPALGGQRGFRKERKRMASGNGLPPSSAMVAKRPSALGPFPRYVWIHQDTPQDSLDKICHDIWKRVQGLPESLQPRTSLEKLSAPMTATVSFQEEALELSGGKDEISLLVEQEFLSLTKEHLILVQESSGELATPIVTPQGTRELAPCFLVPPLGADSTEYPGSSVTAGDKLREQKLSVPIISSRQDCDSAMSTVTGILRAAKVKSVKGTKDKSHSLSASNSEISKLLAQFPLKSTEMSKAPDNKMVLEETKVIKDFLQNSMFNGSGPREPMGLGPFLLLPPPPPPAPPDKLPEFSPPKRQLPVFAKICSKNEADSTLDGHHWIERTPGSKELTKGRESLFISQWPQSRKDTCGEEGHNDSIGTISMTLPTKKPVWPAEKNLLYEFFGATKNPSGQLRLRSKVDMDGLDLKFNPPALMPDKNNIKYAGNVFAPRFTTALTSTTLNQPLWLNLNCPPPPVFSNHSTFPQYQGLYPQRSTRMPYQQPVHPPMGCYSRQVTPYNPQQMGQQIFRSSYTPLMSYIPLVQPNYPYPQRTPQKLPANPRDPTPMAGDGPPYLFPQGYGFNSASSGPLMNSPYFSSSGNGIRF", "length": 596, "header": "tr|A0A8C2M247-1|A0A8C2M247_CRIGR Isoform 1 of Uncharacterized protein C1orf94 homolog OS=Cricetulus griseus OX=10029 GN=CUNH1orf94 PE=4 SV=1 CANONICAL=A0A8C2M247-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M247", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M247" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. 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"MRAGGPQSLCLPALGGQRGFRKERKRMASGNGLPPSSALVAKRPSALGPFPRYVWIHQDTPQDSLDKICHDIWKRVQGLPESLQPRTSLEKHSAPVTAAVSFQEEALELSGGKDEISLLVEQEFLSLTKEHLILVQEGSGELATPIVTPQGTRELAPCFLVPPLGADSAEYAGSSVMAGDEIQEQKLSMPIIGSRQDSDSAMSTVTGILRSAKVKSVKGTKDKGHSLGASNSEISKLLAQFPLKATEMSKAPDNKMVLEETKVIKDFLQNSMFNGSGPREPMGLGPFLLLPPPPPPALPDKLPESSPPKRQLPVFAKICSKTEADAALEGHHWIERSPGTKELTKSRESLFLNQWPQNRKDTCGEEGHSDPVGTISMTLPTKKPVWPAEKNLLYEFFGATKNPSGQLRLRTKVDMDGLDLKFNSPTTVPEKNNIKYAGNVFAPRFTTTLTSTTLNQPLWLNLNCPPPPVFSSHSTFPQYQGLYPQRSTRMPYQQPIHPPLGCYSRQVTPYNPQQMGQQIFRSSYTPLMSYIPFVQPNYPYPQRTPQKLPANPRDPPPTAGDGPQFLFPQGYGFNSAPSGPLMNSPYFSSSGNGIRF", "length": 596 }, "evidence": [ { "id": "A0A8C2M247", "url": "https://omabrowser.org/oma/group/A0A8C2M247/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0RBI8-1", "protein_name": "Similar to human chromosome 1 open reading frame 94", "gene_name": "C5h1orf94", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M275", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M275" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100758543", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100758543", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1N2W6-1", "protein_name": "Regulator of G protein signaling 13", "gene_name": "RGS13", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRRNCWICKMCRDESKRPPSNLTLEEVLQWAQSFETLMATKYGPVVYAAYLKTEHSDENIKFWMACETYKKTASQWSRTSRAKKLYKVYIQPQSPREINIDSSTREAIIKNIQEPTQTCFEEAQKIVYMHMERDSYPRFLKSEMYQKLLKTIQANNNS", "length": 159 }, "evidence": [ { "id": "A0A8C2M275", "url": "https://omabrowser.org/oma/group/A0A8C2M275/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8V0YFV7-1", "protein_name": "Regulator of G protein signaling 13", "gene_name": "RGS13", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MANYCLILQLLNIAQFTLSSDSRSRRMSPNTCWLCKTFRAEENGIISKVSLDEVLQWSQSFEKLIRSKHGPMIYKTYLKTEHSDENIEFWLACEAYKKITSQRKRIYVARKLFTSYIQPQAPKEINIDSPVKKSIIRNLQEPTQSCFDEAQRVVYMHMERDSYPRFLESKFYQQLKYRLRTDNNIPSVR", "length": 189 }, "evidence": [ { "id": "A0A8C2M275", "url": "https://omabrowser.org/oma/group/A0A8C2M275/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZCS1-1", "protein_name": "Regulator of G-protein signaling 13", "gene_name": "Rgs13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRHICWICKLCRHESKRLPSNLTLDEVLKWAQSLESLMATKYGPVVYTAYLKLEHSDENIKFWMACETYKKIASRRGRISRAKKLYNLYIQPQSPREINIDSTTREAIIKSIREPTQTCFEEAQKIVYMHMEMDSYPRFLKSEMYQKLLKTVQSKSC", "length": 158 }, "evidence": [ { "id": "A0A8C2M275", "url": "https://omabrowser.org/oma/group/A0A8C2M275/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O14921-1", "protein_name": "Regulator of G protein signaling 13", "gene_name": "RGS13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRRNCWICKMCRDESKRPPSNLTLEEVLQWAQSFENLMATKYGPVVYAAYLKMEHSDENIQFWMACETYKKIASRWSRISRAKKLYKIYIQPQSPREINIDSSTRETIIRNIQEPTETCFEEAQKIVYMHMERDSYPRFLKSEMYQKLLKTMQSNNSF", "length": 159 }, "evidence": [ { "id": "A0A8C2M275", "url": "https://omabrowser.org/oma/group/A0A8C2M275/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K443-1", "protein_name": "Regulator of G protein signaling 13", "gene_name": "Rgs13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRHICWICKLCRDESKRLPSNLTLDEVLKWAQSLESLMATKYGPIVYTAYLKLEHSDENIKFWMACETYKKIASRRGRISRAKKLYNIYIQPQSPREINIDSTTREAIIKSIREPTQTCFEEAQKIVYMHMEMDSYPRFLKSEMYQQLLKTVQSQSS", "length": 158 }, "evidence": [ { "id": "A0A8C2M275", "url": "https://omabrowser.org/oma/group/A0A8C2M275/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M275", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M275" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M275", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M275" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M275", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M275" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of signal transduction", "id": "GO:0009968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009968", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M275", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M275" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2M275", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M275" }, { "id": "PS50132", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50132" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RGS", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 150, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 22, "end_pos": 24 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2M294-1", "uniprot_ac": "A0A8C2M294", "uniprot_id": "A0A8C2M294_CRIGR", "mass": { "chemical_mass": 152760.0, "monoisotopic_mass": 152760.0 }, "refseq": { "ac": "XP_003498109", "name": "RNA polymerase II-associated protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498109" }, "gene_names": [ { "name": "Rpap1", "type": "recommended", "evidence": [ { "id": "A0A8C2M294", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M294" } ] }, { "name": "Rpap1", "type": "synonym", "evidence": [ { "id": "XP_003498109", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498109" } ] } ], "protein_names": [ { "name": "RNA polymerase II-associated protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003498109", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498109" }, { "id": "A0A8C2M294", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M294/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613677.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003498109", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498109" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M294", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M294" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Rpap1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M294", "locus": {} } ], "crossref": [ { "id": "100762111", "url": "https://www.ncbi.nlm.nih.gov/gene/100762111", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013929", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013929", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039913", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039913", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100762111", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762111", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KYFLQCV", "url": "https://omabrowser.org/oma/group/KYFLQCV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8C2M294", "url": "https://www.orthodb.org/?gene=A0A8C2M294", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21483", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21483", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21483:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21483:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25766", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25766", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003498109", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003498109", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2M294", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M294", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M294-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M294-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JZL0", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7JZL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7JZL0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAE8", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7KAE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7KAE8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMLSRPKPGESEVDLLRFQSQFLEAGAAPAVQLVKGSRRHGDAHPDQLPLQDRRDVVMLDNLPDLPPALVPAPAKKARPSPGHSLPHDEDPEERLSRHDQHITAVLSKIIERDTSSVTVTLPVPSGVAFPPVFHRSQERQGKSAAPGKRSIFAQEIAARRVTEDRVSAARGAVPSLDPPEGAVLSETPSSRDKGSQFPGGSHDFHRSNLVTGKGLRSQAAEQEVQTIHEENVARLQAMDPKEILKEQQQLLAQLDPSLVAFLRSHSHALEQAGTKATKEQSPGRPTVPVTTEESVVSASTSEPRTEEKLEPKAPALKLPVTPHKEWLHMDTVELEKLHWTQDLPPLRRQQTQERMQARFSLQGELLAPDVDLPTHLGLHHHGEEAERAGYSLQELFHLTRSQVSQQRALALHVLSQIISRAQAGEFGDRLVGSILRLLLDAGFLFLLRFSLDDRVDGVIAAAVRALRTLLVAPGDEELLDSTFSWYHGALVFPLMPSQENKDDEDEDEEPTTRKAKKTPEEESRPPPDLARHDVIKGLLATNLLPRLRYVLEVTCPGPSVVLDILAVLIRLARHSLESATRVLECPRLIETIVQEFLPTNWSPVGVGPTSSLYKVPCAAAMKLLRVLASAGRNIAARLLSSFDFRSRLCRFIAEAPQELALPPEEAETLSTEAFRLWAVVASYGQGGDLYRELYPVLMRALQTLPTELSTHPPQPLSMQRMASLLTLLTQLTLAASSAHPEPTSGSAEACVSAIPSSITWTQVSGLQPLVEPCLKQILKFLPRPDVWSALGPVPSACLLFLGAYYQAWSQQSGLCPEDWLQDVERLLDEFLLPLLSQSSLDYLWDSLRHCSPLCNPLSCAPAPEALPSLVSLGCAGGCPPLSVAGSASPFPFLTALLSLFNILLRIHKGLCGQLAAVLAAPGLQQYFLQCVTPMPAPQLTPFSAWALHHEYHLQYLVLSLAQKVATLKPELAANTALHHAVALVLLSRLLPGSEYLAQELLLSCVFRLEFLPENATGGPEAADFSDGLSLGNSGDPQCRRGALLVQACQDLPSIRSCYLAHCSPARASLLTSQALYRGELLRVSSLLLPVPKEPLLPTDWPFQPLIHLYHRASDTPSGLPAADTVGTAVRVLQWALVLESWRPEALCAVPPAARLARLMCVFLVDSELFRETPIQHLVAALLARLCRPQVLPSLNLDCPLPGLASFPDLYASFLEHFEAVSFGDHLFGALVLLPLQRRFSVTLRLALFGEHVGVLRALGLPLTQLPVPLECYTEPAEDSLALLQLYFRALVTGALRPHWCPVLYTVAVAHVNSFIFSQDPKSPDEVKAARKNMLQKTWLLADEGLRQHLLHYKLPNSSLPEGFELYSQLPRLRQQHLQTLPTEGLQNGGSKT", "length": 1392, "header": "tr|A0A8C2M294-1|A0A8C2M294_CRIGR Isoform 1 of RNA polymerase II-associated protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Rpap1 PE=3 SV=1 CANONICAL=A0A8C2M294-1" }, "isoforms": [ { "isoform_ac": "A0A8C2M294-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M294/entry#A0A8C2M294-1", "sequence": { "sequence": "MMLSRPKPGESEVDLLRFQSQFLEAGAAPAVQLVKGSRRHGDAHPDQLPLQDRRDVVMLDNLPDLPPALVPAPAKKARPSPGHSLPHDEDPEERLSRHDQHITAVLSKIIERDTSSVTVTLPVPSGVAFPPVFHRSQERQGKSAAPGKRSIFAQEIAARRVTEDRVSAARGAVPSLDPPEGAVLSETPSSRDKGSQFPGGSHDFHRSNLVTGKGLRSQAAEQEVQTIHEENVARLQAMDPKEILKEQQQLLAQLDPSLVAFLRSHSHALEQAGTKATKEQSPGRPTVPVTTEESVVSASTSEPRTEEKLEPKAPALKLPVTPHKEWLHMDTVELEKLHWTQDLPPLRRQQTQERMQARFSLQGELLAPDVDLPTHLGLHHHGEEAERAGYSLQELFHLTRSQVSQQRALALHVLSQIISRAQAGEFGDRLVGSILRLLLDAGFLFLLRFSLDDRVDGVIAAAVRALRTLLVAPGDEELLDSTFSWYHGALVFPLMPSQENKDDEDEDEEPTTRKAKKTPEEESRPPPDLARHDVIKGLLATNLLPRLRYVLEVTCPGPSVVLDILAVLIRLARHSLESATRVLECPRLIETIVQEFLPTNWSPVGVGPTSSLYKVPCAAAMKLLRVLASAGRNIAARLLSSFDFRSRLCRFIAEAPQELALPPEEAETLSTEAFRLWAVVASYGQGGDLYRELYPVLMRALQTLPTELSTHPPQPLSMQRMASLLTLLTQLTLAASSAHPEPTSGSAEACVSAIPSSITWTQVSGLQPLVEPCLKQILKFLPRPDVWSALGPVPSACLLFLGAYYQAWSQQSGLCPEDWLQDVERLLDEFLLPLLSQSSLDYLWDSLRHCSPLCNPLSCAPAPEALPSLVSLGCAGGCPPLSVAGSASPFPFLTALLSLFNILLRIHKGLCGQLAAVLAAPGLQQYFLQCVTPMPAPQLTPFSAWALHHEYHLQYLVLSLAQKVATLKPELAANTALHHAVALVLLSRLLPGSEYLAQELLLSCVFRLEFLPENATGGPEAADFSDGLSLGNSGDPQCRRGALLVQACQDLPSIRSCYLAHCSPARASLLTSQALYRGELLRVSSLLLPVPKEPLLPTDWPFQPLIHLYHRASDTPSGLPAADTVGTAVRVLQWALVLESWRPEALCAVPPAARLARLMCVFLVDSELFRETPIQHLVAALLARLCRPQVLPSLNLDCPLPGLASFPDLYASFLEHFEAVSFGDHLFGALVLLPLQRRFSVTLRLALFGEHVGVLRALGLPLTQLPVPLECYTEPAEDSLALLQLYFRALVTGALRPHWCPVLYTVAVAHVNSFIFSQDPKSPDEVKAARKNMLQKTWLLADEGLRQHLLHYKLPNSSLPEGFELYSQLPRLRQQHLQTLPTEGLQNGGSKT", "length": 1392, "header": "tr|A0A8C2M294-1|A0A8C2M294_CRIGR Isoform 1 of RNA polymerase II-associated protein 1 isoform X1 OS=Cricetulus griseus OX=10029 GN=Rpap1 PE=3 SV=1 CANONICAL=A0A8C2M294-1" }, "locus": {} }, { "isoform_ac": "A0A9J7JZL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M294/entry#A0A9J7JZL0-1", "sequence": { "sequence": "MMLSRPKPGESEVDLLRFQSQFLEAGAAPAVQLVKGSRRHGDAHPDQLPLQDRRDVVMLDNLPDLPPALVPAPAKKARPSPGHSLPHDEDPEERLSRHDQHITAVLSKIIERDTSSVTVTLPVPSGVAFPPVFHRSQERQGKSAAPGKRSIFAQEIAARRVTEDRVSAARGAVPSLDPPEGAVLSETPSSRDKGSQFPGGSHDFHRSNLVTGKGLRSQAAEQEVQTIHEENVARLQAMDPKEILKEQQQLLAQLDPSLVAFLRSHSHALEQAGTKATKEQSPGRPTVPVTTEESVVSASTSEPRTEEKLEPKAPALKLPVTPHKEWLHMDTVELEKLHWTQDLPPLRRQQTQERMQARFSLQGELLAPDVDLPTHLGLHHHGEEAERAGYSLQELFHLTRSQVSQQRALALHVLSQIISRAQAGEFGDRLVGSILRLLLDAGFLFLLRFSLDDRVDGVIAAAVRALRTLLVAPGDEELLDSTFSWYHGALVFPLMPSQENKDDEDEDEEPTTRKAKKTPEEESRPPPDLARHDVIKGLLATNLLPRLRYVLEVTCPGPSVVLDILAVLIRLARHSLESATRVLECPRLIETIVQEFLPTNWSPVGVGPTSSLYKVPCAAAMKLLRVLASAGRNIAARLLSSFDFRSRLCRFIAEAPQELALPPEEAETLSTEAFRLWAVVASYGQGGDLYRELYPVLMRALQTLPTELSTHPPQPLSMQRMASLLTLLTQLTLAASSAHPEPTSGSAEACVSAIPSSITWTQVSGLQPLVEPCLKQILKFLPRPDVWSALGPVPSACLLFLGAYYQAWSQQSGLCPEDWLQDVERLLDEFLLPLLSQSSLDYLWDSLRHCSPLCNPLSCAPAPEALPSLVSLGCAGGCPPLSVAGSASPFPFLTALLSLFNILLRIHKGLCGQLAAVLAAPGLQQYFLQCVTPMPAPQLTPFSAWALHHEYHLQYLVLSLAQKVATLKPELAANTALHHAVALVLLSRLLPGSEYLAQELLLSCVFRLEFLPENATGGPEAADFSDGLSLGNSGDPQCRRGALLVQACQDLPSIRSCYLAHCSPARASLLTSQALYRGELLRVSSLLLPVPKEPLLPTDWPFQPLIHLYHRASDTPSGLPAADTVGTAVRVLQWALVLESWRPEALCAVPPAARLARLMCVFLVDSELFRETPIQHLVAALLARLCRPQVLPSLNLDCPLPGLASFPDLYASFLEHFEAVSFGDHLFGALVLLPLQRRFSVTLRLALFGEHVGVLRALGLPLTQLIISLCTAACAVGVLHRAC", "length": 1283, "header": "tr|A0A9J7JZL0-1|A0A9J7JZL0_CRIGR Computationally mapped isoform of RNA polymerase II-associated protein 1 isoform X2 OS=Cricetulus griseus OX=10029 GN=Rpap1 PE=3 SV=1 CANONICAL=A0A8C2M294-1" }, "locus": {} }, { "isoform_ac": "A0A9J7KAE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M294/entry#A0A9J7KAE8-1", "sequence": { "sequence": "MEEHEQNSWDLMTQGEVFPCAVLSETPSSRDKGSQFPGGSHDFHRSNLVTGKGLRSQAAEQEVQTIHEENVARLQAMDPKEILKEQQQLLAQLDPSLVAFLRSHSHALEQAGTKATKEQSPGRPTVPVTTEESVVSASTSEPRTEEKLEPKAPALKLPVTPHKEWLHMDTVELEKLHWTQDLPPLRRQQTQERMQARFSLQGELLAPDVDLPTHLGLHHHGEEAERAGYSLQELFHLTRSQVSQQRALALHVLSQIISRAQAGEFGDRLVGSILRLLLDAGFLFLLRFSLDDRVDGVIAAAVRALRTLLVAPGDEELLDSTFSWYHGALVFPLMPSQENKDDEDEDEEPTTRKAKKTPEEESRPPPDLARHDVIKGLLATNLLPRLRYVLEVTCPGPSVVLDILAVLIRLARHSLESATRVLECPRLIETIVQEFLPTNWSPVGVGPTSSLYKVPCAAAMKLLRVLASAGRNIAARLLSSFDFRSRLCRFIAEAPQELALPPEEAETLSTEAFRLWAVVASYGQGGDLYRELYPVLMRALQTLPTELSTHPPQPLSMQRMASLLTLLTQLTLAASSAHPEPTSGSAEACVSAIPSSITWTQVSGLQPLVEPCLKQILKFLPRPDVWSALGPVPSACLLFLGAYYQAWSQQSGLCPEDWLQDVERLLDEFLLPLLSQSSLDYLWDSLRHCSPLCNPLSCAPAPEALPSLVSLGCAGGCPPLSVAGSASPFPFLTALLSLFNILLRIHKGLCGQLAAVLAAPGLQQYFLQCVTPMPAPQLTPFSAWALHHEYHLQYLVLSLAQKVATLKPELAANTALHHAVALVLLSRLLPGSEYLAQELLLSCVFRLEFLPENATGGPEAADFSDGLSLGNSGDPQCRRGALLVQACQDLPSIRSCYLAHCSPARASLLTSQALYRGELLRVSSLLLPVPKEPLLPTDWPFQPLIHLYHRASDTPSGLPAADTVGTAVRVLQWALVLESWRPEALCAVPPAARLARLMCVFLVDSELFRETPIQHLVAALLARLCRPQVLPSLNLDCPLPGLASFPDLYASFLEHFEAVSFGDHLFGALVLLPLQRRFSVTLRLALFGEHVGVLRALGLPLTQLPVPLECYTEPAEDSLALLQLYFRALVTGALRPHWCPVLYTVAVAHVNSFIFSQDPKSPDEVKAARKNMLQKTWLLADEGLRQHLLHYKLPNSSLPEGFELYSQLPRLRQQHLQTLPTEGLQNGGSKT", "length": 1231, "header": "tr|A0A9J7KAE8-1|A0A9J7KAE8_CRIGR Computationally mapped isoform of RNA polymerase II-associated protein 1 isoform X3 OS=Cricetulus griseus OX=10029 GN=Rpap1 PE=3 SV=1 CANONICAL=A0A8C2M294-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "other", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 609, "start_aa": "Thr", "end_pos": 609, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr609", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ], "filter_code": "00000000000000001000.00000000001000.0.01000" } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. Bioeng.", "date": "2018", "authors": "Rupp Oliver, MacDonald Madolyn L, Li Shangzhong, Dhiman Heena, Polson Shawn, Griep Sven, Heffner Kelley, Hernandez Inmaculada, Brinkrolf Karina, Jadhav Vaibhav, Samoudi Mojtaba, Hao Haiping, Kingham Brewster, Goesmann Alexander, Betenbaugh Michael J, Lewis Nathan E, Borth Nicole, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M294", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M294" } ], "reference": [ { "type": "PubMed", "id": "29704459", "url": "https://glygen.org/publication/PubMed/29704459" } ] }, { "title": "Chromosome-scale scaffolds for the Chinese hamster reference genome assembly to facilitate the study of the CHO epigenome.", "journal": "Biotechnol. Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M294", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M294" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:100762111", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100762111", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZBS1-1", "protein_name": "RNA polymerase II associated protein 1", "gene_name": "RPAP1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MMFSRPKPGESEADLIHFQNQFLAARASPAVKIVKKADKRKGEERSTDAERPQLQDSKDVVMLDDFPDVLPALTPGPPKKSKIKSACVHFSDEDPEERLENHDQHITAVFSKIIERDTSAEAVTMPVPTGDPFPRIFHRSEIKSEVKVGSGRKSIFAQKMAARRAAEKPATAPSAECTQIASAPLDILNPEGSAEEVPRSSNRDNKADDIFTSQRPCIITGEGLGSQKSEQEAQAIHKENLEKLQSMSQEEILKEQERLLAQLDPSLVAFLKSRRSGNVDQKNEIKMEQNRPEEFVESLTVPQCAVGMSLSMQESGLEESVRRDESTKMEITDDDLPVKPRKEWIHMDNVEFEKLEWMKDLPPPRQKKTKKGMQARFSLKGDLIPADADLPTHLGLHHHGEEAERAGYSLQELFHLSRSQLIQQRTLALQVLGRIVQKARAGEFASSLKGSVLRLLLDAGFLFLLRFSLDDAVDNVMAASVGALRALLVSSDDEKYLDWTFSWYQGMAAFPFVPNNEEEEEEEEEEEEELTGAEKSQNKKQTDENKPDADVARYDAVKGLLKTRIQHRLRYILEVVRPVPTVVLDILHILTHIARHSSEACIQLLDCPRLIDTIVREFLPTRWDPHVAEPGCLLTSLHGVACAAAMKFIRVLASGGRNATARLLNKFEMKSRLIRFTAEDPQDLLLPREEAIRLSTEAFRLWAVAAGYGQACDLYRDLYPVLVRILQSLPELLSTSHEKNPMFELSVQRAAAVVTLLVHVTQTAGYAVELHAKLSSCEDGEQIPPPPITWNQVSGLQPFLETSMKKFLQVISWTETWQILQPLTTTYMIYLGVYYSACSQQPSVNPVDFLEELERLTSEVLQPLLSQPAMHSMWDLLRPCSALCNPLSCSPAPESVFSIVSLSCTGGKPPLSLVGSKSPFPFLTALLFLIDSITHIHKGLISKYSSVLSIEGLKDYLHQSWQTAPPSVTPASAWMLRHEYHLQYFALVLARKMAGTCPDYSRHASLHHCVAMALLSRLLPGSEHLAYEILLDLAFNPEFLPEGKTGGPEAADFSDILHLGTSAKLSQPGSAAVSSSKPTRGALLRESYQNLPAIRSCYLSHFVHLQPALVRSQASYQGRNYLIQSMLLPEVRGPILPSDWPFFPLISLYNKVTNAETRGAVLNSLPLDLVNTVTWNLQWVLLLESWRPKTLQSIPIAAKLARLMCIFLTGGDLFLEAPIHCYTAALLSVYCQPKALDSLNLDAPLPGLASFHDLYISLLEQFEGVSFGDPLFGVFVLLPLQKRFSVHLRLSVFGEHTSILRALGVPLQQFPVPLERYTSPPEDNLNLLRHYFRTLVTGALRNTWCPVLYVVAVAHVNSFIFSQDSTTQEADAARKSMLRKTWLLVDETLKKHLLYYRLLNAESPLGFDLYEQLPPIRLKYLQMVTQKENKENAPVLVS", "length": 1438 }, "evidence": [ { "id": "A0A8C2M294", "url": "https://omabrowser.org/oma/group/A0A8C2M294/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0JN53-1", "protein_name": "RNA polymerase II-associated protein 1", "gene_name": "RPAP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLSRPKPGESEVDLLRFQSQFLAAGATPAVQLVKKGSRRAGDANLEQPPLQDHRDVVMLDSLPDLPPALVPAPPKRARPSPGHLLPEHEDPEERLHRHDQHITAVLTKIIERDTSSMPVNLPVSSGVAFPPVFHRSQGRQGKPVTAGKRSIFAQEIAARRASGAKVSPVREVESILDPPESAMTCEALTPREWGSQPPWNSYSFQGPHLVTGKGLKGQEAEQEAQTIHEENVARLQALAPEEILQEQQRLLAQLDPSLVAFLKSHSCTREQAEEKATREQRPGRPSAEVIGKEAIAPTSASVPRQENELEPETPALALPVTPQKEWLHMDTVELEKLHWTQDLPPLRRQQTQERMQARFSLQGELLAPDMDLPTHLGLHHHGEEAERAGYSLQELFHLTRSQVSQQRALALHVLAQVIGRAQAGEFGDRLVGSVLHLLLDAGFLFLLRFSLDDRVDGVIAAAVRALRALLVAPGDEELLDSTFSWYHGALMFALMPSQEDKEDEDEDEEPPAEKAKTKSPEEGNRPPSDLARHDIIKGLLATNLLPRLRYVLEVTCPGPSVVLDILTVLIRLARHSLESATRVLECPRLVETVVREFLPTSWSPMGSGPTSSLHRVPCAPAMKLLRVLASASRNIAARLLSGFDLRSRLSRFIAEDPQDLALPLEEAETLSTEAFRLWAVAASYGLGSDLYRELYPVLMQALQDVPKELSSPPPRPLAVQRIASLLTLLTQLTLAAGHIAPEHNSHSAEASLLAGSSSVTWTQVSGLQPLVEPCLRQTLKLLPRPEMWSALGPVPTACLLFLDAYYQAWSQQPGLCPEDWLQDMERLSEGLLLPLLKHPSLGSLWDSLGCCSPLCNPQSCAVAPETISSLASLGCAGGHPPLSLAGSASPFPFLTALLSLLNTLGRIHKGLCGQLATVLAAPGLQDYFLRCVAPVAALHLTPFSAWALRHEYHLQYLALTLAQRAATLQPPMSGTDAALCHGMALALLGRLLPGSEHLAHELMLSCVFRLEFLPERASGGPEAADFSDRLSLGSGGDLGCGRGALLAQACQDLPSIRSCYLTHCSLARASLLASQALYRGELQRVPALLLPVPKEPLLPTDWPFLPLIQLYHRASDTPSGLPPADTVGTALRALQWVLVLESWRPRALWAVSPAARLARLMCVFLVDSELFRETPIQRLVAALLARLCQPEVLSNLNLDCPLPGLTSFPDLYANFLEHFEAVSFGDHLFGALILLPLQRRFSVTLRLALFGEHVGALRALGLPLTQLPVSLECYTAPPEDNLALLQLYFRALVTGALRPRWCPVLYAVAVAHVNSFIFSQDPNNSDEIKAACRSMLQKTWLLTDEGLRQHLLHYKLPNSALPEGFELYPQLPPLRQQYLQKLRISGVLPNGVSDT", "length": 1395 }, "evidence": [ { "id": "A0A8C2M294", "url": "https://omabrowser.org/oma/group/A0A8C2M294/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3T1I9-1", "protein_name": "RNA polymerase II-associated protein 1", "gene_name": "Rpap1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMLSRPKPGESEVDLLRFQSQFLEAGAAPAVQLVKGSRRRGDAHPDQLPPQDHRDVVMLDSLPDLPPALLPAPSKRARPSPGRPLPHDEDPEERLNRHDEHITAVLSKIVERDTSSVTVTLPVPSGVAFPPVFHRSQERQVKPAASSKRSIFAQEIAARRVSDNRAPSAEQVVPSPDAPEGAVPCETPSSKDRGSQLPGRSHSFHRPNLITGKGLRSQAAVQEVQTIHEENVARLQAMDPEEILKEQQQLLAQLDPSLVAFLRAHNHTREQTETKATKEQNPERPSVPVSKEEPIMSTCTGESGTRDKLEDKLEDKLQPRTPALKLPMTPNKEWLHMDTVELEKLHWTQDLPPLRRQQTQERMQARFSLQGELLEPDVDLPTHLGLHHHGEEAERAGYSLQELFHLTRSQVSQQRALALHVLSHIVGRAQAGEFGDRLVGSVLRLLLDAGFLFLLRFSLDDRIDSVIAAAVRALRALLVAPGDEELLDSTFSWYHGASVFPMMPSHDDKEDEDEDEELTKEKVNRKTPEEGSRPPPDLARHDVIKGLLATNLLPRFRYVLEVTCPGPSVVLDILAVLIRLARHSLESAMRVLECPRLMETIVREFLPTSWSPIGVGPAPSLYKVPCAAAMKLLRVLASAGRNIAARLLSSFDVRSRLCRFIAEAPRDLALPFEEAEILTTEAFRLWAVAASYGQGGDLYRELYPVLMRALQTLPPELSTHPLQPLSMQRMASLLTLLTQLTLAASTQPEATSGSVESCVVAIPSSITWTHVSGLKPLVEPCLKQTLKFLRRPDVWNALGPVPSACLLFLGAYYQTWSQQSGLCPEDWLQDMERFLDEFLLPLLSQPPLGRMWDSLRDCSPLCNPLSCASTPEALPSLVSLGCAGGCPPLSVAGSASPFPFLTALLSLINTLGQIHKGLCRQLAVVLTAPGLQNYFLQCVAPAPAPQLTPFSAWALRHEYHLQYLVLSLAQKAATSQPEPAASTALHHVMALVLLSRLLPGSEFLAHELLLSCVFRLGFLPENASGGPEAADFSDGLSLGNSGDPHCRRGALLVQACQDLPSIRSCYLAHCSPARASLLTSQALYRGELPRVSSLLLPVPKEPLLPTDWPFQPLIHLYHRASDTPSGLPAADTVGITMRVLQWVLVLESWRPEALWAVPPAARLARLMCVYLVDSELFRETPIQRLVAALLARLCQPQVLPNLKLDCPLPGLTSFPDLYASFLDHFEAVSFGDHLFGALVLLPLQRRFSVTLRLALFGEHVGVLRALGLPLAQLPVPLECYTEPAEDSLALLQLYFRALVTGALHARWCPVLYTVAVAHVNSFVFCQDPKSSDEVKAARRSMLQKVWLLADKDLRQHLLHYKLPNSSLPEGFELYPQLPRLRQQYLQTLPTEVLQNGGFKT", "length": 1400 }, "evidence": [ { "id": "A0A8C2M294", "url": "https://omabrowser.org/oma/group/A0A8C2M294/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80TE0-1", "protein_name": "RNA polymerase II-associated protein 1", "gene_name": "Rpap1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMLSRPKPGESEVDLLRFQSQFLEAGAAPAVQLVKGSRRHGDAPPDRLPPQDHRDVVMLDNLPDLPPALLPAPAKRARPSPGHPLPHDEDPEERLNRHDQHITAVLSKIVERDTSSVTVTLPVPSGVAFPPVFHRSQERQVKPAASGKRSIFAQEIAARRVSGNRVTSAEQVVPSLDTPEGAVPCETPSFRDRSNQLPGRSHGFHRPNLVTGKGLRSKVAEQEVQTIHEENVARLQAMDPEEILKEQQQLLAQLDPSLVAFLRSHSQVQEQTGTKATKKQSPKRPSVLVTKEEPVTSTRTREPRTGDKLEEKPEATVEDKMEDKLQPRTPALKLPMTPSKDWLHMDTVELDKLHWTQDLPPLRRQQTQERMQARFSLQGELLAPDVDLPTHLGLHHHGEEAERAGYSLQELFHLTRSQVSQQRALALQVLSQIVGRAQAGEFGDRLVGSVLRLLLDAGFLFLLRFSLDDRVDSVIAAAVRALRTLLVAPGDEELLDRTFSWYHGASVFPLMPSQDDKEDEDEDEELETEKVKRKTPEEGSRPPPDLARHDVIKGLLATNLLPRLRYVLEVTCPGPSVILDILAVLIRLARHSLESAMRVLECPRLMETIVQEFLPTSWSPIGVGPTPSLYKVPCASAMKLLRVLASAGRNIAARLLSGFDVRSRLCRFIAEAPHDLALPPEEAEILTTEAFRLWAVAASYGQGGDLYRELYPVLLRALQTLPTELSAHPLQPLAMQRVAALFTLLTQLTLAASSIPPEPASGPAESCVPAIPSSVTWTQVSGLKPLVEPCLKQTLKFLPRPDVWNALGPVPSACLLFLGAYYQAWSRQSHLCPEDWLQDMERLLDESLLPLLSQPPLGSLWDSLRDCSPLCNPLSCASNPEALPSLVSLGCAGGCPPLSVAGSASPFPFLTALLSLINTLVQSHKGLCGQLSAVLTAPGLQNYFLQCVAPAPAPQLTPFSAWALHHEYHLQYLVLSFAHKAATLQPEPAASTALHHAVALVLLSRLLPGSEYLAQELLLSCVFRLEFLPESASGGPEAADFSDGLSLGSSGDPQCRRGALLVQACRDLPSIRSCYLAHCSPARASLLSSQALYCGELLRVSSLLLPVPKEPLLATDWPFQPLIHLYHRASDTPSGPPAADTVGVAMRVLQWVLVLESWRPEVLWAVPPAARLARLMCVYLVDSELFRETPIQRLVAALLARLCRPQVLPNLKLDCPLPGLTSFPDLYASFLDHFEAVSFGDHLFGALVLLPLQRRFSVTLRLALFGEHVGVLRALGLPLTQLPVPLECYTEPAEDSLPLLQLYFRALVTGTLRARWCPILYTVAVAHVNSFIFCQDPKSSDEVKTARRSMLQRTWLLTDEGLRQHLLHYKLPNSSLPEGFELYSQLPRLRQQCLQTLPTEGLQNGGVKT", "length": 1409 }, "evidence": [ { "id": "A0A8C2M294", "url": "https://omabrowser.org/oma/group/A0A8C2M294/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BWH6-1", "protein_name": "RNA polymerase II-associated protein 1", "gene_name": "RPAP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSRPKPGESEVDLLHFQSQFLAAGAAPAVQLVKKGNRGGGDANSDRPPLQDHRDVVMLDNLPDLPPALVPSPPKRARPSPGHCLPEDEDPEERLRRHDQHITAVLTKIIERDTSSVAVNLPVPSGVAFPAVFLRSRDTQGKSATSGKRSIFAQEIAARRIAEAKGPSVGEVVPNVGPPEGAVTCETPTPRNQGCQLPGSSHSFQGPNLVTGKGLRDQEAEQEAQTIHEENIARLQAMAPEEILQEQQRLLAQLDPSLVAFLRSHSHTQEQTGETASEEQRPGGPSANVTKEEPLMSAFASEPRKRDKLEPEAPALALPVTPQKEWLHMDTVELEKLHWTQDLPPVRRQQTQERMQARFSLQGELLAPDVDLPTHLGLHHHGEEAERAGYSLQELFHLTRSQVSQQRALALHVLAQVISRAQAGEFGDRLAGSVLSLLLDAGFLFLLRFSLDDRVDGVIATAIRALRALLVAPGDEELLDSTFSWYHGALTFPLMPSQEDKEDEDEDEECPAGKAKRKSPEEESRPPPDLARHDVIKGLLATSLLPRLRYVLEVTYPGPAVVLDILAVLIRLARHSLESATRVLECPRLIETIVREFLPTSWSPVGAGPTPSLYKVPCATAMKLLRVLASAGRNIAARLLSSFDLRSRLCRIIAEAPQELALPPEEAEMLSTEALRLWAVAASYGQGGYLYRELYPVLMRALQVVPRELSTHPPQPLSMQRIASLLTLLTQLTLAAGSTPAETISDSAEASLSATPSLVTWTQVSGLQPLVEPCLRQTLKLLSRPEMWRAVGPVPVACLLFLGAYYQAWSQQPSSCPEDWLQDMQRLSEELLLPLLSQPTLGSLWDSLRHCSLLCNPLSCVPALEAPPSLVSLGCSGGCPRLSLAGSASPFPFLTALLSLLNTLAQIHKGLCGQLAAILAAPGLQNYFLQCVAPGAAPHLTPFSAWALRHEYHLQYLALALAQKAAALQPLPATHAALYHGMALALLSRLLPGSEYLTHELLLSCVFRLEFLPERTSGGPEAADFSDQLSLGSSRVPRCGQGTLLAQACQDLPSIRNCYLTHCSPARASLLASQALHRGELQRVPTLLLPMPTEPLLPTDWPFLPLIRLYHRASDTPSGLSPTDTMGTAMRVLQWVLVLESWRPQALWAVPPAARLARLMCVFLVDSELFRESPVQHLVAALLAQLCQPQVLPNLNLDCRLPGLTSFPDLYANFLDHFEAVSFGDHLFGALVLLPLQRRFSVTLRLALFGEHVGALRALSLPLTQLPVSLECYTVPPEDNLALLQLYFRTLVTGALRPRWCPVLYAVAVAHVNSFIFSQDPQSSDEVKAARRSMLQKTWLLADEGLRQHLLHYKLPNSTLPEGFELYSQLPPLRQHYLQRLTSTVLQNGVSET", "length": 1393 }, "evidence": [ { "id": "A0A8C2M294", "url": "https://omabrowser.org/oma/group/A0A8C2M294/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VTX1-1", "protein_name": "RNA polymerase II-associated protein 1", "gene_name": "anon-69Ag", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFKKLKPGESEEDVLRMAAEFNAERAKDPNFQPAAAFVRMDKAPKKSMFAQRREQAKLGRVTSTTEKNEEQIQPVPKEIIPQIPTSVPKERGSHVSQVLLDEIQENILGDVKGSKMDPSSLGNVLGELVERTEGTRRSAFPETKNVDSSKPLSIFAKQLLGAKSSTKEKSNKVSDFPRNDTSSIIKDAKLGKELHQENLNVLKQMNEQDILTEKERLLASLDPSLIALLSKKRQTTPNSKPPNPNSPKVIEAPPMPAQSTRAQDPQISSLTDGNPAIELLQESDKGNWLNFNLVEEHKLAWMRDIPAKISELKPGEQFNARFDWKGVLLPHTLKDQDASKQIDERELYLHGEEADRPGYALQELFRLARSTVLQQRLSAFGAIAGIFSIYNQGFYDQVLSLPISKIFFLLRFGLDDNAPAQLEVVSRALSNLFYNETDEVLLDHVHDNAYCHWQPTLEVLGNGSDGNGEDTDTNSIAFLQRYMKLLTTSKSVRAEVDEDESESRTSMDDFQLAETDLMDCLLRTNILQRIRFILVSVKPDNSTVESCLKLLIRIARTSTKVARQLANESHLIDTLFKHFLPSSSGSNQFYGQPQVLFLKLIRVLICHHLDIAKGISKGVLITRLQQYLFLQDNKVQMVRIQIEALRILRCLLLLGIVDRDIFRQFLPALRQLLDWHGNHCAFDGVGGSGLVRQHAAALLVALVASGESGACDVEGQKLLVEPLNNCCCGWMHAASRVAKIKDFSQMTLLSAALYAVGWFSRNSLLGTTSFLPFLRSILPKFVQSSGFIACVHDLVKGSIMLRRPIDRRHVHAPLPNVGAVLMHDYGPQLVVSETYPVHLLSNLWALLAISLDSGEKPLFEALIQPAVLEPLAEYLRQLSTQLNRVLATNFFARSELRFIHQLLTTDGIEIYLKRQQMLQLVYNYLCCLSTAHATQIKSIFERFIFNGDFVKLDESSLKLLQQSCLEMVYPHIIADNSEPSLSLSYTQAPILPTDWPFFQLRVILSNYLQNVQQRPAAIHSENQVVLMTLTFVRQLEREGLQIVSPLEKLMYLMIAFMGPDSQFLAPDLHELLRDCLMDFYRENAAHEFDFDAELVDKARFEPLYYLFVEHFEAASYGDELFSSLVLVPLAQKYDNKWRRRLWSEHVQAVRFINCDESMLMGGLFAYLEPVEEEPSLVKLYGDALAQKMVRPGSIAYRIAQHHFNHSKSVHKATLF", "length": 1215 }, "evidence": [ { "id": "A0A8C2M294", "url": "https://omabrowser.org/oma/group/A0A8C2M294/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M294", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M294" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "transcription by RNA polymerase II", "id": "GO:0006366", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006366", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M294", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M294" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1014, "end_pos": 1016, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1356, "end_pos": 1358, "annotation": "n_glycosylation_sequon" }, { "start_pos": 600, "end_pos": 602, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8C2M294", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M294" }, { "id": "PF08620", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08620" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RPAP1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 356, "end_pos": 421, "start_aa": "Gln", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2M294", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M294" }, { "id": "PF08621", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08621" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RPAP1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 225, "end_pos": 265, "start_aa": "Gln", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8C2M294", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M294" }, { "id": "PF25766", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25766" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RPAP1/MINIYO-like TPR repeats", "eco_id": "ECO_0000259", "start_pos": 1101, "end_pos": 1321, "start_aa": "Pro", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 609 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1014, "end_pos": 1016 }, { "start_pos": 1356, "end_pos": 1358 }, { "start_pos": 600, "end_pos": 602 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2M2D4-1", "uniprot_ac": "A0A8C2M2D4", "uniprot_id": "A0A8C2M2D4_CRIGR", "mass": { "chemical_mass": 41804.0, "monoisotopic_mass": 41804.0 }, "refseq": { "ac": "XP_003501881", "name": "zinc finger MYND domain-containing protein 12 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501881" }, "gene_names": [ { "name": "Zmynd12", "type": "recommended", "evidence": [ { "id": "A0A8C2M2D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2D4" } ] }, { "name": "Zmynd12", "type": "synonym", "evidence": [ { "id": "XP_003501881", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501881" } ] } ], "protein_names": [ { "name": "Zinc finger MYND domain-containing protein 12 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A8C2M2D4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2D4/entry#names_and_taxonomy" } ] }, { "name": "zinc finger MYND domain-containing protein 12 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003501881", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501881" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## assembly gap :: added 323 transcript bases to patch genome assembly gap ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613862.1) and transcript sequence (IACG01076182.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Apr 30, 2014 this sequence version replaced XP_003501881.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003501881", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501881" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M2D4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2D4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Zmynd12", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2D4", "locus": {} } ], "crossref": [ { "id": "100759994", "url": "https://www.ncbi.nlm.nih.gov/gene/100759994", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002893", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002893", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053248", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053248", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100759994", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100759994", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2M2D4", "url": "https://www.orthodb.org/?gene=A0A8C2M2D4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46533", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46533", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46533:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46533:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01753", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01753", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003501881", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003501881", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2M2D4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2D4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M2D4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2D4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FE22", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FE22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A9J7FE22-1", "url": "https://www.uniprot.org/uniprotkb/A0A9J7FE22-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"XP_016820962", "name": "testis-expressed protein 38", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016820962" }, "gene_names": [ { "name": "Tex38", "type": "recommended", "evidence": [ { "id": "A0A8C2M2E4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2E4" } ] }, { "name": "Tex38", "type": "synonym", "evidence": [ { "id": "XP_016820962", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016820962" } ] } ], "protein_names": [ { "name": "Testis-expressed protein 38", "type": "synonym", "evidence": [ { "id": "A0A8C2M2E4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2E4/entry#names_and_taxonomy" } ] }, { "name": "testis-expressed protein 38", "type": "synonym", "evidence": [ { "id": "XP_016820962", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016820962" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003613647.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_016820962", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016820962" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M2E4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2E4" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Tex38", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2E4", "locus": {} } ], "crossref": [ { "id": "100769829", "url": "https://www.ncbi.nlm.nih.gov/gene/100769829", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:100769829", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:100769829", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2M2E4", "url": "https://www.orthodb.org/?gene=A0A8C2M2E4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR37362", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37362", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37362:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37362:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15834", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15834", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_016820962", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_016820962", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2M2E4", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2E4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M2E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2E4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSQKEDLRLPGMWISLSIGFLGLCSSLIGSCILFLHWKKNLQREEDVQQWVEVMRAAMFTYSPLLYWINKRRHHGMNAAINTGPPPAVTKAEAQNPDSLWELDISEDGNYAVQDSSPRGEASSPLQHVPVVPKQSPSSTMPQPRTDSPHPLPIFQEVPSAVSLCNLPPMLNHSVSYPLANRPEKNVHFCSLPILAHETNCFNAKPFASEL", "length": 211, "header": "tr|A0A8C2M2E4-1|A0A8C2M2E4_CRIGR Isoform 1 of Testis-expressed protein 38 OS=Cricetulus griseus OX=10029 GN=Tex38 PE=4 SV=1 CANONICAL=A0A8C2M2E4-1" }, "isoforms": [ { "isoform_ac": "A0A8C2M2E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2E4/entry#A0A8C2M2E4-1", "sequence": { "sequence": "MDSQKEDLRLPGMWISLSIGFLGLCSSLIGSCILFLHWKKNLQREEDVQQWVEVMRAAMFTYSPLLYWINKRRHHGMNAAINTGPPPAVTKAEAQNPDSLWELDISEDGNYAVQDSSPRGEASSPLQHVPVVPKQSPSSTMPQPRTDSPHPLPIFQEVPSAVSLCNLPPMLNHSVSYPLANRPEKNVHFCSLPILAHETNCFNAKPFASEL", "length": 211, "header": "tr|A0A8C2M2E4-1|A0A8C2M2E4_CRIGR Isoform 1 of Testis-expressed protein 38 OS=Cricetulus griseus OX=10029 GN=Tex38 PE=4 SV=1 CANONICAL=A0A8C2M2E4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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"MTTRALEELDGGLGSCPVDEDLSALADPCPGQPREDRARATSRLADSSSWPHDSQERAPEGGPIGSVDLDARPKKTEKEPVAKVASGPGKEKLKAGATPRSPARKKAQASPPPRPPPTPPALSEELPWGDLTLNKCLVLASLVALLGSACQLCREAVAGEAEARVPVPVPWVTPSSAPKESASPLPKSVAWAPPLGQPQPQAKEEERAKVPEVPGSREAAGKDEGESEEAAGEEPKERPKKEERLRKEQLRKEERPRKERPRKKKSQKEERPRAARETREALLRRWEAREGGHRPWAQDPGDSEYRKRQAWASLLHRAEEDRPRGRGRQKQRTGKGRD", "length": 338 }, "evidence": [ { "id": "A0A8C2M2L9", "url": "https://omabrowser.org/oma/group/A0A8C2M2L9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4A2V6-1", "protein_name": "Junctional sarcoplasmic reticulum protein 1", "gene_name": "Jsrp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTRGLEDLDGGLGSCIPSDDLPFLEESPSGRRPDSKTRGTSRLSDSSSWSHVLQDPVTAGAGDAGLKKTEKERMGKESAPAGKAGASPRSIPARRKPQAAPPLQPPLPPSDDELPWGDLTLNKCLVLASLLALLGSAFQLCRDAVAGEAVAAPQQWVPPSSPTKKPASPTPAPAPAPKPPVLVPPSGPPQPKPGPPAPQAEMRDEPELPGSPEAAETQAEPGGSISEASGEESAPLGDRGSQEKPQKEKPRKGEKPKKEKPRREKPRREEKPQVTREPRQSLRQRWEAREGGHRPWRRDSRDLEHGKLKAWAPRRRHDQHDRDNRPRQRPRVGKRHD", "length": 338 }, "evidence": [ { "id": "A0A8C2M2L9", "url": "https://omabrowser.org/oma/group/A0A8C2M2L9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3MI48-1", "protein_name": "Junctional sarcoplasmic reticulum protein 1", "gene_name": "Jsrp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTTRGLEDLDGGLGSCLPSDDLPFLEEPASGRRRESKARGTSRRADSSDWTHVLQDPVAAGAGDAGLKKMEKELAGKESTAGKAGTSPRIVPARRKPQAPPPLQPPPPPLQPPPRTPSDDLPWGDLTLNKCLVLASLVALLGSALQLCRDAVAGEVVAAPHPWVPPSSPPKKEASPAPKPPVLVSPSGSPQPKPGPPQARMQDEPELPGSPEATETRVERGGSISEASGEESVPLGDRGSQEKPRKEKPSKGEKLKKEKPRREKPRREDKSQVTGEPRQSLPRRWEAREGGRRPWGRDSRDLLEHGKLQAWAPRRRHDRDDRPRQKRGKGRD", "length": 332 }, "evidence": [ { "id": "A0A8C2M2L9", "url": "https://omabrowser.org/oma/group/A0A8C2M2L9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96MG2-1", "protein_name": "Junctional sarcoplasmic reticulum protein 1", "gene_name": "JSRP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSMTTRAWEELDGGLGSCQALEDHSALAETQEDRASATPRLADSGSVPHDSQVAEGPSVDTRPKKMEKEPAARGTPGTGKERLKAGASPRSVPARKKAQTAPPLQPPPPPPALSEELPWGDLSLNKCLVLASLVALLGSAFQLCRDAVPGEAALQARVPEPWVPPSSAPREPSSPLPKFEAQAPPSAPPAPRAEAEVRPKIPGSREAAENDEEEPGEATGEAVREDRVTLADRGPKERPRREGKPRKEKPRKEERPKKERPRKEERPRAAREPREALPQRWESREGGHRPWARDSRDAEPRKKQAWVSPRRPDEEQRPGSRQKLRAGKGRD", "length": 331 }, "evidence": [ { "id": "A0A8C2M2L9", "url": "https://omabrowser.org/oma/group/A0A8C2M2L9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "skeletal muscle contraction", "id": "GO:0003009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003009", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M2L9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2L9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "sarcoplasmic reticulum", "id": "GO:0016529", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016529", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M2L9", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2L9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 59 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": 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"XP_027266347", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266347" } ] } ], "protein_names": [ { "name": "IQ domain-containing protein M isoform X2", "type": "synonym", "evidence": [ { "id": "XP_027266347", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266347" }, { "id": "A0A8C2M2P2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2P2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Cricetulus griseus Annotation Release 104 Annotation Version :: 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048596.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jul 10, 2020 this sequence version replaced XP_027266347.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027266347", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266347" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M2P2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2P2" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "Iqcm", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2P2", "locus": {} } ], "crossref": [ { "id": "107977012", "url": "https://www.ncbi.nlm.nih.gov/gene/107977012", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:107977012", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:107977012", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2M2P2", "url": "https://www.orthodb.org/?gene=A0A8C2M2P2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35978", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35978", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35978:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35978:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_027266347", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027266347", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2M2P2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2P2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M2P2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2P2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATEEAMPEGAKGPVLETTQKDFLQEAKSLIAQHYKRINENKTQGTSINVFKNKHQKPKTGKYIPFDIKRSEILNVVQEHRTVLRSISFPKETSKCSPLMEDSQQMASTEPHFPNLKEKYQSVDLFKREKVNLGKIMTDIESVSKKMEKEKQLHLKKSGLLEPLHSHLSLPMPRMDSSSSSTELLRDHEERVLYDWRNIALTRASYLPEESSQSLLTPDYYKDYFTKALKKKELQSIKPDETPEKSSKTVVKSDKLDSKVKRIGPHIEIYQVFQGKNKLIFTKRIIKLITITQAHIRGWLERKRLQRIKTKSLYHGPNLKTVICMYQCLIHRVRHRLGLWRTRQIINFGELEEWMDRKKFYETMFAKREDWQGLERSELLKYFNDCGHFPTQSQIDEHLDLFHRHSPGKYSEVIKKSSAIELLFTLYPPRGAKVNISTRLRSTWLRPIVNGEEGYKYIVSGHPILKRANIRTAGKLVARSIRERKMRQFYKL", "length": 492, "header": "tr|A0A8C2M2P2-1|A0A8C2M2P2_CRIGR Isoform 1 of IQ domain-containing protein M isoform X2 OS=Cricetulus griseus OX=10029 GN=Iqcm PE=4 SV=1 CANONICAL=A0A8C2M2P2-1" }, "isoforms": [ { "isoform_ac": "A0A8C2M2P2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2P2/entry#A0A8C2M2P2-1", "sequence": { "sequence": "MATEEAMPEGAKGPVLETTQKDFLQEAKSLIAQHYKRINENKTQGTSINVFKNKHQKPKTGKYIPFDIKRSEILNVVQEHRTVLRSISFPKETSKCSPLMEDSQQMASTEPHFPNLKEKYQSVDLFKREKVNLGKIMTDIESVSKKMEKEKQLHLKKSGLLEPLHSHLSLPMPRMDSSSSSTELLRDHEERVLYDWRNIALTRASYLPEESSQSLLTPDYYKDYFTKALKKKELQSIKPDETPEKSSKTVVKSDKLDSKVKRIGPHIEIYQVFQGKNKLIFTKRIIKLITITQAHIRGWLERKRLQRIKTKSLYHGPNLKTVICMYQCLIHRVRHRLGLWRTRQIINFGELEEWMDRKKFYETMFAKREDWQGLERSELLKYFNDCGHFPTQSQIDEHLDLFHRHSPGKYSEVIKKSSAIELLFTLYPPRGAKVNISTRLRSTWLRPIVNGEEGYKYIVSGHPILKRANIRTAGKLVARSIRERKMRQFYKL", "length": 492, "header": "tr|A0A8C2M2P2-1|A0A8C2M2P2_CRIGR Isoform 1 of IQ domain-containing protein M isoform X2 OS=Cricetulus griseus OX=10029 GN=Iqcm PE=4 SV=1 CANONICAL=A0A8C2M2P2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Bioeng.", "date": "2020", "authors": "Hilliard William, MacDonald Madolyn L, Lee Kelvin H", "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M2P2", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2P2" } ], "reference": [ { "type": "PubMed", "id": "32410221", "url": "https://glygen.org/publication/PubMed/32410221" } ] } ], "pathway": [ { "id": "cge:107977012", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:107977012", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 435, "end_pos": 437, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], 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}, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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"sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ], "tool_support": { "graph_view": "yes" } }, { "uniprot_canonical_ac": "A0A8C2M2Z8-1", "uniprot_ac": "A0A8C2M2Z8", "uniprot_id": "A0A8C2M2Z8_CRIGR", "mass": { "chemical_mass": 12403.0, "monoisotopic_mass": 12403.0 }, "refseq": { "ac": "XP_027280281", "name": "60S ribosomal protein L36a-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280281" }, "gene_names": [ { "name": "LOC103160177", "type": "recommended", "evidence": [ { "id": "A0A8C2M2Z8", "database": "UniProtKB", "url": 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_048600.1) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_027280281", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280281" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Cricetulus griseus", "taxid": 10029, "evidence": [ { "database": "UniProtKB", "id": "A0A8C2M2Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2Z8" } ], "common_name": "Chinese hamster", "glygen_name": "Hamster", "reference_species": "Cricetulus griseus [10029]" } ], "gene": [ { "name": "LOC103160177", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2Z8", "locus": {} } ], "crossref": [ { "id": "103160177", "url": "https://www.ncbi.nlm.nih.gov/gene/103160177", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000552", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000552", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011332", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011332", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053708", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053708", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "cge:103160177", "url": "https://www.genome.jp/dbget-bin/www_bget?cge:103160177", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8C2M2Z8", "url": "https://www.orthodb.org/?gene=A0A8C2M2Z8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10369", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10369", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00935", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00935", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_027280281", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_027280281", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8C2M2Z8", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2Z8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8C2M2Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2Z8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVNVPKIRRTFCKKCGKHQPHKMTQYKKGKDSLYAQGKRCYDRKQSGYGRQTKPIFRKKAKTTKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 105, "header": "tr|A0A8C2M2Z8-1|A0A8C2M2Z8_CRIGR Isoform 1 of 60S ribosomal protein L36a-like OS=Cricetulus griseus OX=10029 GN=LOC103160177 PE=3 SV=1 CANONICAL=A0A8C2M2Z8-1" }, "isoforms": [ { "isoform_ac": "A0A8C2M2Z8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8C2M2Z8/entry#A0A8C2M2Z8-1", "sequence": { "sequence": "MVNVPKIRRTFCKKCGKHQPHKMTQYKKGKDSLYAQGKRCYDRKQSGYGRQTKPIFRKKAKTTKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 105, "header": "tr|A0A8C2M2Z8-1|A0A8C2M2Z8_CRIGR Isoform 1 of 60S ribosomal protein L36a-like OS=Cricetulus griseus OX=10029 GN=LOC103160177 PE=3 SV=1 CANONICAL=A0A8C2M2Z8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A reference genome of the Chinese hamster based on a hybrid assembly strategy.", "journal": "Biotechnol. 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Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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