[ { "uniprot_canonical_ac": "Q9NU22-1", "uniprot_ac": "Q9NU22", "uniprot_id": "MDN1_HUMAN", "mass": { "chemical_mass": 632820.0, "monoisotopic_mass": 632820.0 }, "refseq": { "ac": "NP_055426", "name": "midasin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_055426" }, "gene_names": [ { "name": "MDN1", "type": "recommended", "evidence": [ { "id": "Q9NU22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9NU22" } ] }, { "name": "KIAA0301", "type": "synonym", "evidence": [ { "id": "Q9NU22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9NU22" } ] }, { "name": "MDN1", "type": "synonym", "evidence": [ { "id": "NP_055426", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_055426" } ] }, { "name": "Rea1", "type": "synonym", "evidence": [ { "id": "NP_055426", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_055426" } ] } ], "protein_names": [ { "name": "Midasin", "type": "recommended", "evidence": [ { "id": "Q9NU22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9NU22/entry#names_and_taxonomy" } ] }, { "name": "Dynein-related AAA-ATPase MDN1", "type": "synonym", "evidence": [ { "id": "Q9NU22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9NU22/entry#names_and_taxonomy" } ] }, { "name": "MDN1, midasin homolog", "type": "synonym", "evidence": [ { "id": "NP_055426", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_055426" } ] }, { "name": "MIDAS-containing protein", "type": "synonym", "evidence": [ { "id": "NP_055426", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_055426" }, { "id": "Q9NU22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q9NU22/entry#names_and_taxonomy" } ] }, { "name": "dynein-related AAA-ATPase MDN1", "type": "synonym", "evidence": [ { "id": "NP_055426", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_055426" } ] }, { "name": "midasin", "type": "synonym", "evidence": [ { "id": "NP_055426", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_055426" } ] } ], "function": [ { "annotation": "Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits (PubMed:27814492). Functions at successive maturation steps to remove ribosomal factors at critical transition points, first driving the exit of early pre-60S particles from the nucleolus and then driving late pre-60S particles from the nucleus (By similarity). At an early stage in 60S maturation, mediates the dissociation of the PeBoW complex (PES1-BOP1-WDR12) from early pre-60S particles, rendering them competent for export from the nucleolus to the nucleoplasm (By similarity). Subsequently recruited to the nucleoplasmic particles through interaction with SUMO-conjugated PELP1 complex (PubMed:27814492). This binding is only possible if the 5S RNP at the central protuberance has undergone the rotation to complete its maturation (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q9NU22", "url": "https://www.uniprot.org/uniprotkb/Q9NU22#function" }, { "database": "UniProtKB", "id": "Q12019", "url": "https://www.uniprot.org/uniprotkb/Q12019#function" }, { "database": "PubMed", "id": "27814492", "url": "https://glygen.org/publication/PubMed/27814492" } ] }, { "annotation": "The crystal structure of the UBL domain of the WDR12 homologue from S. cerevisiae at 1.7 A resolution is reported and demonstrated that human midasin binds to WDR12 as well as Nle1 through their respective UBL domains.", "evidence": [ { "database": "RefSeq", "id": "NP_055426", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_055426" }, { "database": "PubMed", "id": "26601951", "url": "https://glygen.org/publication/PubMed/26601951" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [ { "tissue": { "name": "Adult mammalian kidney", "namespace": "UBERON", "id": "0000082", "url": "http://purl.obolibrary.org/obo/UBERON_0000082" }, "score": "80.56", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000112159", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000112159" } ] }, { "tissue": { "name": "Oral cavity", "namespace": "UBERON", "id": "0000167", "url": "http://purl.obolibrary.org/obo/UBERON_0000167" }, "score": "74.48", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000112159", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000112159" } ] }, { "tissue": { "name": "Stomach", "namespace": "UBERON", "id": "0000945", "url": "http://purl.obolibrary.org/obo/UBERON_0000945" }, "score": "74.34", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000112159", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000112159" } ] }, { "tissue": { "name": "Uterus", "namespace": "UBERON", "id": "0000995", "url": "http://purl.obolibrary.org/obo/UBERON_0000995" }, "score": "57.08", "present": "LOW", "evidence": [ { "database": "Bgee", "id": "ENSG00000112159", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000112159" } ] }, { "tissue": { "name": "Esophagus", "namespace": "UBERON", "id": "0001043", "url": "http://purl.obolibrary.org/obo/UBERON_0001043" }, "score": "86.37", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000112159", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000112159" } ] }, { "tissue": { "name": "Rectum", "namespace": "UBERON", "id": "0001052", "url": "http://purl.obolibrary.org/obo/UBERON_0001052" }, "score": "79.91", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000112159", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000112159" } ] }, { "tissue": { "name": "Colon", "namespace": "UBERON", "id": "0001155", "url": "http://purl.obolibrary.org/obo/UBERON_0001155" }, "score": "62.27", "present": "LOW", "evidence": [ { "database": "Bgee", "id": "ENSG00000112159", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000112159" } ] }, { "tissue": { "name": "Urinary bladder", "namespace": "UBERON", "id": "0001255", "url": "http://purl.obolibrary.org/obo/UBERON_0001255" }, "score": "81.96", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000112159", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000112159" } ] }, { "tissue": { "name": "Thyroid gland", "namespace": "UBERON", "id": "0002046", "url": "http://purl.obolibrary.org/obo/UBERON_0002046" }, "score": "90.13", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000112159", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000112159" } ] }, { "tissue": { "name": "Lung", "namespace": "UBERON", "id": "0002048", "url": "http://purl.obolibrary.org/obo/UBERON_0002048" }, "score": "64.47", "present": "LOW", "evidence": [ { "database": "Bgee", "id": "ENSG00000112159", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000112159" } ] }, { "tissue": { "name": "Liver", "namespace": "UBERON", "id": "0002107", "url": "http://purl.obolibrary.org/obo/UBERON_0002107" }, "score": "87.71", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000112159", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000112159" } ] }, { "tissue": { "name": "Prostate gland", "namespace": "UBERON", "id": "0002367", "url": "http://purl.obolibrary.org/obo/UBERON_0002367" }, "score": "87.67", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000112159", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000112159" } ] }, { "tissue": { "name": "Thoracic mammary gland", "namespace": "UBERON", "id": "0005200", "url": "http://purl.obolibrary.org/obo/UBERON_0005200" }, "score": "85.62", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000112159", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000112159" } ] } ], "expression_disease": [ { "significant": "No", "trend": "down", "name": "Prostate cancer [DO disease name]", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "database": "BioXpress", "id": "Q9NU22", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/Q9NU22" } ], "disease": [ { "disease_id": "DOID:10283", "recommended_name": { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate." }, "synonyms": [ { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "NGP - new growth of prostate", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "hereditary prostate cancer", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "malignant tumor of the prostate", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "prostate cancer, familial", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "prostate neoplasm", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "prostatic cancer", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "prostatic neoplasm", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "tumor of the prostate", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, hereditary, X-linked 1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "HPCX1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, hereditary, X-linked 1", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "prostate cancer, hereditary, X-linked 2", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "HPCX2", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "prostate cancer, hereditary, X-linked 2", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the RNASEL gene." }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "RNASEL familial prostate cancer", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "familial prostate cancer caused by mutation in RNASEL", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, type 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "HPC1", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, type 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "HPC8", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, type 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, susceptibility to, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "HPC3", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, type 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "HPC4", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, type 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "HPC5", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, type 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "HPC6", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "HPC7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, type 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "HPC9", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "HPC10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the EHBP1 gene." }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "EHBP1 familial prostate cancer", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "familial prostate cancer caused by mutation in EHBP1", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, type 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "HPC12", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the MSMB gene." }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "MSMB familial prostate cancer", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "familial prostate cancer caused by mutation in MSMB", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, type 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "HPC13", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "HPC11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "HPC14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "HPC15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0700275", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0700275", "name": "prostate cancer, hereditary", "description": "An instance of prostate cancer that is caused by an inherited genomic modification in an individual. Familial prostate cancer (FPC) is a malignant tumor of the prostate with an early onset. FPC is either asymptomatic or causes mictionary symptoms, erectile dysfunction, bone pain, venous compression and infectious or inflammatory syndrome (for the metastatic forms). It is also characterized by familial antecedents." }, { "id": "MIM:601518", "resource": "MIM", "url": "https://www.omim.org/entry/601518", "name": "Prostate cancer, hereditary, 1", "description": "Prostate cancer, hereditary, 1" }, { "id": "MIM:610997", "resource": "MIM", "url": "https://www.omim.org/entry/610997", "name": "Prostate cancer, hereditary, 9", "description": "Prostate cancer, hereditary, 9" }, { "id": "MIM:611868", "resource": "MIM", "url": "https://www.omim.org/entry/611868", "name": "Prostate cancer, hereditary, 12", "description": "Prostate cancer, hereditary, 12" }, { "id": "MIM:611928", "resource": "MIM", "url": "https://www.omim.org/entry/611928", "name": "Prostate cancer, hereditary, 13", "description": "Prostate cancer, hereditary, 13" }, { "id": "MIM:611955", "resource": "MIM", "url": "https://www.omim.org/entry/611955", "name": "Prostate cancer, hereditary, 11", "description": "Prostate cancer, hereditary, 11" }, { "id": "MIM:176807", "resource": "MIM", "url": "https://www.omim.org/entry/176807", "name": "Prostate cancer", "description": "Prostate cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ] } ] }, { "significant": "Yes", "trend": "up", "name": "Stomach cancer [DO disease name]", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "database": "BioXpress", "id": "Q9NU22", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/Q9NU22" } ], "disease": [ { "disease_id": "DOID:10534", "recommended_name": { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach." }, "synonyms": [ { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "gastric cancer", "description": "" }, { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "A primary or metastatic malignant neoplasm involving the stomach." }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca lesser curvature - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "GC", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "cancer of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer risk after h. pylori infection", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer, somatic", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumor", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumour", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant stomach neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "stomach cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca body - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "ca greater curvature of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of body of stomach", "description": "" }, { "id": "MIM:613659", "resource": "MIM", "url": "https://www.omim.org/entry/613659", "name": "Gastric cancer", "description": "Gastric cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" }, { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ] } ] }, { "significant": "No", "trend": "down", "name": "Urinary bladder cancer [DO disease name]", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "database": "BioXpress", "id": "Q9NU22", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/Q9NU22" } ], "disease": [ { "disease_id": "DOID:11054", "recommended_name": { "id": "DOID:11054", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder." }, "synonyms": [ { "id": "DOID:11054", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11054", "name": "bladder cancer", "description": "" }, { "id": "DOID:11054", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11054", "name": "tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder cancer", "description": "A primary or metastatic malignant neoplasm involving the bladder." }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "tumour of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "bladder cancer, somatic", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "cancer of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder tumour", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm, bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm, urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor, urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant 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This region includes the nasal cavity, sinuses, lips, mouth, salivary glands, throat, or larynx." }, "synonyms": [ { "id": "DOID:11934", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11934", "name": "head and neck neoplasm", "description": "" }, { "id": "DOID:11934", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11934", "name": "head and neck tumours", "description": "" }, { "id": "DOID:11934", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11934", "name": "head/neck neoplasm", "description": "" }, { "id": "DOID:11934", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11934", "name": "tumor of head and neck", "description": "" } ], "unlinked_id_list": [ "DOID:1542" ], "evidence": [ { "id": "11934", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11934" } ] } ] }, { "significant": "No", "trend": "up", "name": "Lung cancer [DO disease name]", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "database": "BioXpress", "id": "Q9NU22", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/Q9NU22" } ], "disease": [ { "disease_id": "DOID:1324", "recommended_name": { "id": "DOID:1324", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung." }, "synonyms": [ { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer", "description": "A malignant neoplasm involving the lung." }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "adenocarcinoma of lung, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "adenocarcinoma of lung, somatic", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "cancer of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, protection against, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, resistance to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, somatic", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung neoplasm", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung tumor", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung tumour", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant neoplasm of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant neoplasm of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumor of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumor of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumour of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumour of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "nonsmall cell lung cancer, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "nonsmall cell lung cancer, somatic", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "nonsmall cell lung cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility 1", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "LNCR1", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility 1", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "lung cancer susceptibility 3", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "LNCR3", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "lung cancer susceptibility 3", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "lung cancer susceptibility 4", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "LNCR4", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "lung cancer susceptibility 4", "description": "" }, { "id": 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}, { "id": "8QL1", "url": "https://www.rcsb.org/structure/8QL1", "database": "PDB", "categories": [ "3D Structure" ] }, { "id": "PF07728", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07728", "database": "Pfam", "categories": [ "Other", "Protein Classification" ] }, { "id": "PF17865", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17865", "database": "Pfam", "categories": [ "Other", "Protein Classification" ] }, { "id": "PF17867", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17867", "database": "Pfam", "categories": [ "Other", "Protein Classification" ] }, { "id": "PF21108", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21108", "database": "Pfam", "categories": [ "Other", "Protein Classification" ] }, { "id": "Q9NU22", "url": "https://pharos.nih.gov/targets/Q9NU22", "database": "PHAROS", "categories": [ "Organism-specific" ] }, { "id": "PR:Q9NU22", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q9NU22", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_055426", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_055426", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q9NU22", "url": "https://www.uniprot.org/uniprotkb/Q9NU22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q9NU22-1", "url": "https://www.uniprot.org/uniprotkb/Q9NU22-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEHFLLEVAAAPLRLIAAKNEKSRSELGRFLAKQVWTPQDRQCVLSTLAQLLLDKDCTVLVGRQLRPLLLDLLERNAEAIKAGGQINHDLHERLCVSMSKLIGNHPDVLPFALRYFKDTSPVFQRLFLESSDANPVRYGRRRMKLRDLMEAAFKFLQQEQSVFRELWDWSVCVPLLRSHDTLVRWYTANCLALVTCMNEEHKLSFLKKIFNSDELIHFRLRLLEEAQLQDLEKALVLANPEVSLWRKQKELQYLQGHLVSSDLSPRVTAVCGVVLPGQLPAPGELGGNRSSSREQELALRSYVLVESVCKSLQTLAMAVASQNAVLLEGPIGCGKTSLVEYLAAVTGRTKPPQLLKVQLGDQTDSKMLLGMYRCTDVPGEFVWQPGTLTQAATMGHWILLEDIDYAPLDVVSVLIPLLENGELLIPGRGDCLKVAPGFQFFATRRLLSCGGNWYRPLNSHATLLDKYWTKIHLDNLDKRELNEVLQSRYPSLLAVVDHLLDIYIQLTGEKHHSWSDSSVGCEQAPEEVSEARRENKRPTLEGRELSLRDLLNWCNRIAHSFDSSSLSASLNIFQEALDCFTAMLSEHTSKLKMAEVIGSKLNISRKKAEFFCQLYKPEIVINELDLQVGRVRLLRKQSEAVHLQREKFTFAATRPSSVLIEQLAVCVSKGEPVLLVGETGTGKTSTIQYLAHITGHRLRVVNMNQQSDTADLLGGYKPVDHKLIWLPLREAFEELFAQTFSKKQNFTFLGHIQTCYRQKRWHDLLRLMQHVHKSAVNKDGKDSETGLLIKEKWEAFGLRLNHAQQQMKMTENTLLFAFVEGTLAQAVKKGEWILLDEINLAAPEILECLSGLLEGSSGSLVLLDRGDTEPLVRHPDFRLFACMNPATDVGKRNLPPGIRNRFTELYVEELESKEDLQVLIVDYLKGLSVNKNTVQGIINFYTALRKESGTKLVDGTGHRPHYSLRTLCRALRFAASNPCGNIQRSLYEGFCLGFLTQLDRASHPIVQKLICQHIVPGNVKSLLKQPIPEPKGGRLIQVEGYWIAVGDKEPTIDETYILTSSVKLNLRDIVRVVSAGTYPVLIQGETSVGKTSLIQWLAAATGNHCVRINNHEHTDIQEYIGCYTSDSSGKLVFKEGVLIDAMRKGYWIILDELNLAPTDVLEALNRLLDDNRELLVTETQEVVKAHPRFMLFATQNPPGLYGGRKVLSRAFRNRFVELHFDELPSSELETILHKRCSLPPSYCSKLVKVMLDLQSYRRSSSVFAGKQGFITLRDLFRWAERYRLAEPTEKEYDWLQHLANDGYMLLAGRVRKQEEIDVIQEVLEKHFKKKLCPQSLFSKENVLKLLGKLSTQISTLECNFGHIVWTEGMRRLAMLVGRALEFGEPVLLVGDTGCGKTTICQVFAALANQKLYSVSCHLHMETSDFLGGLRPVRQKPNDKEEIDTSRLFEWHDGPLVQAMKEDGFFLLDEISLADDSVLERLNSVLEVEKSLVLAEKGSPEDKDSEIELLTAGKKFRILATMNPGGDFGKKELSPALRNRFTEIWCPQSTSREDLIQIISHNLRPGLCLGRIDPKGSDIPEVMLDFIDWLTHQEFGRKCVVSIRDILSWVNFMNKMGEEAALKRPEIISTVTSFVHAACLVYIDGIGSGVTSSGFGTALLARKECLKFLIKRLAKIVRLTEYQKNELKIYDRMKAKEFTGIDNLWGIHPFFIPRGPVLHRNNIADYALSAGTTAMNAQRLLRATKLKKPILLEGSPGVGKTSLVGALAKASGNTLVRINLSEQTDITDLFGADLPVEGGKGGEFAWRDGPLLAALKAGHWVVLDELNLASQSVLEGLNACFDHRGEIYVPELGMSFQVQHEKTKIFGCQNPFRQGGGRKGLPRSFLNRFTQVFVDPLTVIDMEFIASTLFPAIEKNIVKKMVAFNNQIDHEVTVEKKWGQKGGPWEFNLRDLFRWCQLMLVDQSPGCYDPGQHVFLVYGERMRTEEDKKKVIAVFKDVFGSNSNPYMGTRLFRITPYDVQLGYSVLSRGSCVPHPSRHPLLLLHQSFQPLESIMKCVQMSWMVILVGPASVGKTSLVQLLAHLTGHTLKIMAMNSAMDTTELLGGFEQVDLIRPWRRLLEKVEGTVRALLRDSLLISADDAEVVLRAWSHFLLTYKPKCLGEGGKAITMEIVNKLEAVLLLMQRLNNKINSYCKAEFAKLVEEFRSFGVKLTQLASGHSHGTFEWVDSMLVQALKSGDWLLMDNVNFCNPSVLDRLNALLEPGGVLTISERGMIDGSTPTITPNPNFRLFLSMDPVHGDISRAMRNRGLEIYISGEGDASTPDNLDLKVLLHSLGLVGNSVCDILLALHTETRSTVVGSPTSSVSTLIQTAILIVQYLQRGLSLDRAFSEACWEVYVCSQHSPANRKLVQALLEKHVSSLRAHETWGDSILGMGLWPDSVPSALFATEDSHLSTVRRDGQILVYCLNRMSMKTSSWTRSQPFTLQDLEKIMQSPSPENLKFNAVEVNTYWIDEPDVLVMAVKLLIERATNQDWMLRVKWLYHLAKNIPQGLESIQIHLEASAASLRNFYSHSLSGAVSNVFKILQPNTTDEFVIPLDPRWNMQALDMIRNLMDFDPQTDQPDQLFALLESAANKTIIYLDREKRVFTEANLVSVGSKKLRESVLRMSFEFHQDPESYHTLPHEIVVNLAAFFELCDALVLLWVQSSQGMVSDASANEILGSLRWRDRFWTVADTVKVDAPGLALLALHWHWVLKHLVHQIPRLLMNYEDKYYKEVQTVSEHIQNCLGSQTGGFAGIKKLQKFLGRPFPFKDKLVVECFSQLKVLNKVLAIREQMSALGESGWQEDINRLQVVASQWTLKKSLLQAWGLILRANILEDVSLDELKNFVHAQCLELKAKGLSLGFLEKKHDEASSLSHPDLTSVIHLTRSVQLWPAMEYLAMLWRYKVTADFMAQACLRRCSKNQQPQINEEISHLISFCLYHTPVTPQELRDLWSLLHHQKVSPEEITSLWSELFNSMFMSFWSSTVTTNPEYWLMWNPLPGMQQREAPKSVLDSTLKGPGNLNRPIFSKCCFEVLTSSWRASPWDVSGLPILSSSHVTLGEWVERTQQLQDISSMLWTNMAISSVAEFRRTDSQLQGQVLFRHLAGLAELLPESRRQEYMQNCEQLLLGSSQAFQHVGQTLGDMAGQEVLPKELLCQLLTSLHHFVGEGESKRSLPEPAQRGSLWVSLGLLQIQTWLPQARFDPAVKREYKLNYVKEELHQLQCEWKTRNLSSQLQTGRDLEDEVVVSYSHPHVRLLRQRMDRLDNLTCHLLKKQAFRPQLPAYESLVQEIHHYVTSIAKAPAVQDLLTRLLQALHIDGPRSAQVAQSLLKEEASWQQSHHQFRKRLSEEYTFYPDAVSPLQASILQLQHGMRLVASELHTSLHSSMVGADRLGTLATALLAFPSVGPTFPTYYAHADTLCSVKSEEVLRGLGKLILKRSGGKELEGKGQKACPTREQLLMNALLYLRSHVLCKGELDQRALQLFRHVCQEIISEWDEQERIAQEKAEQESGLYRYRSRNSRTALSEEEEEEREFRKQFPLHEKDFADILVQPTLEENKGTSDGQEEEAGTNPALLSQNSMQAVMLIHQQLCLNFARSLWYQQTLPPHEAKHYLSLFLSCYQTGASLVTHFYPLMGVELNDRLLGSQLLACTLSHNTLFGEAPSDLMVKPDGPYDFYQHPNVPEARQCQPVLQGFSEAVSHLLQDWPEHPALEQLLVVMDRIRSFPLSSPISKFLNGLEILLAKAQDWEENASRALSLRKHLDLISQMIIRWRKLELNCWSMSLDNTMKRHTEKSTKHWFSIYQMLEKHMQEQTEEQEDDKQMTLMLLVSTLQAFIEGSSLGEFHVRLQMLLVFHCHVLLMPQVEGKDSLCSVLWNLYHYYKQFFDRVQAKIVELRSPLEKELKEFVKISKWNDVSFWSIKQSVEKTHRTLFKFMKKFEAVLSEPCRSSLVESDKEEQPDFLPRPTDGAASELSSIQNLNRALRETLLAQPAAGQATIPEWCQGAAPSGLEGELLRRLPKLRKRMRKMCLTFMKESPLPRLVEGLDQFTGEVISSVSELQSLKVEPSAEKEKQRSEAKHILMQKQRALSDLFKHLAKIGLSYRKGLAWARSKNPQEMLHLHPLDLQSALSIVSSTQEADSRLLTEISSSWDGCQKYFYRSLARHARLNAALATPAKEMGMGNVERCRGFSAHLMKMLVRQRRSLTTLSEQWIILRNLLSCVQEIHSRLMGPQAYPVAFPPQDGVQQWTERLQHLAMQCQILLEQLSWLLQCCPSVGPAPGHGNVQVLGQPPGPCLEGPELSKGQLCGVVLDLIPSNLSYPSPIPGSQLPSGCRMRKQDHLWQQSTTRLTEMLKTIKTVKADVDKIRQQSCETLFHSWKDFEVCSSALSCLSQVSVHLQGLESLFILPGMEVEQRDSQMALVESLEYVRGEISKAMADFTTWKTHLLTSDSQGGNQMLDEGFVEDFSEQMEIAIRAILCAIQNLEERKNEKAEENTDQASPQEDYAGFERLQSGHLTKLLEDDFWADVSTLHVQKIISAISELLERLKSYGEDGTAAKHLFFSQSCSLLVRLVPVLSSYSDLVLFFLTMSLATHRSTAKLLSVLAQVFTELAQKGFCLPKEFMEDSAGEGATEFHDYEGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKAHKETENEKPERSRESTIHTAHQFLMDTIFQPFLKDVNELRQELERQLEMWQPRESGNPEEEKVAAEMWQSYLILTAPLSQRLCEELRLILEPTQAAKLKGDYRTGKRLNIRKVIPYIASQFRKDKIWLRRTKPSKRQYQICLAIDDSSSMVDNHTKQLAFESLAVIGNALTLLEVGQIAVCSFGESVKLLHPFHEQFSDYSGSQILRLCKFQQKKTKIAQFLESVANMFAAAQQLSQNISSETAQLLLVVSDGRGLFLEGKERVLAAVQAARNANIFVIFVVLDNPSSRDSILDIKVPIFKGPGEMPEIRSYMEEFPFPYYIILRDVNALPETLSDALRQWFELVTASDHP", "length": 5596, "header": "sp|Q9NU22-1|MDN1_HUMAN Isoform 1 of Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2 CANONICAL=Q9NU22-1" }, "isoforms": [ { "isoform_ac": "Q9NU22-1", "url": "https://www.uniprot.org/uniprotkb/Q9NU22/entry#Q9NU22-1", "sequence": { "sequence": "MEHFLLEVAAAPLRLIAAKNEKSRSELGRFLAKQVWTPQDRQCVLSTLAQLLLDKDCTVLVGRQLRPLLLDLLERNAEAIKAGGQINHDLHERLCVSMSKLIGNHPDVLPFALRYFKDTSPVFQRLFLESSDANPVRYGRRRMKLRDLMEAAFKFLQQEQSVFRELWDWSVCVPLLRSHDTLVRWYTANCLALVTCMNEEHKLSFLKKIFNSDELIHFRLRLLEEAQLQDLEKALVLANPEVSLWRKQKELQYLQGHLVSSDLSPRVTAVCGVVLPGQLPAPGELGGNRSSSREQELALRSYVLVESVCKSLQTLAMAVASQNAVLLEGPIGCGKTSLVEYLAAVTGRTKPPQLLKVQLGDQTDSKMLLGMYRCTDVPGEFVWQPGTLTQAATMGHWILLEDIDYAPLDVVSVLIPLLENGELLIPGRGDCLKVAPGFQFFATRRLLSCGGNWYRPLNSHATLLDKYWTKIHLDNLDKRELNEVLQSRYPSLLAVVDHLLDIYIQLTGEKHHSWSDSSVGCEQAPEEVSEARRENKRPTLEGRELSLRDLLNWCNRIAHSFDSSSLSASLNIFQEALDCFTAMLSEHTSKLKMAEVIGSKLNISRKKAEFFCQLYKPEIVINELDLQVGRVRLLRKQSEAVHLQREKFTFAATRPSSVLIEQLAVCVSKGEPVLLVGETGTGKTSTIQYLAHITGHRLRVVNMNQQSDTADLLGGYKPVDHKLIWLPLREAFEELFAQTFSKKQNFTFLGHIQTCYRQKRWHDLLRLMQHVHKSAVNKDGKDSETGLLIKEKWEAFGLRLNHAQQQMKMTENTLLFAFVEGTLAQAVKKGEWILLDEINLAAPEILECLSGLLEGSSGSLVLLDRGDTEPLVRHPDFRLFACMNPATDVGKRNLPPGIRNRFTELYVEELESKEDLQVLIVDYLKGLSVNKNTVQGIINFYTALRKESGTKLVDGTGHRPHYSLRTLCRALRFAASNPCGNIQRSLYEGFCLGFLTQLDRASHPIVQKLICQHIVPGNVKSLLKQPIPEPKGGRLIQVEGYWIAVGDKEPTIDETYILTSSVKLNLRDIVRVVSAGTYPVLIQGETSVGKTSLIQWLAAATGNHCVRINNHEHTDIQEYIGCYTSDSSGKLVFKEGVLIDAMRKGYWIILDELNLAPTDVLEALNRLLDDNRELLVTETQEVVKAHPRFMLFATQNPPGLYGGRKVLSRAFRNRFVELHFDELPSSELETILHKRCSLPPSYCSKLVKVMLDLQSYRRSSSVFAGKQGFITLRDLFRWAERYRLAEPTEKEYDWLQHLANDGYMLLAGRVRKQEEIDVIQEVLEKHFKKKLCPQSLFSKENVLKLLGKLSTQISTLECNFGHIVWTEGMRRLAMLVGRALEFGEPVLLVGDTGCGKTTICQVFAALANQKLYSVSCHLHMETSDFLGGLRPVRQKPNDKEEIDTSRLFEWHDGPLVQAMKEDGFFLLDEISLADDSVLERLNSVLEVEKSLVLAEKGSPEDKDSEIELLTAGKKFRILATMNPGGDFGKKELSPALRNRFTEIWCPQSTSREDLIQIISHNLRPGLCLGRIDPKGSDIPEVMLDFIDWLTHQEFGRKCVVSIRDILSWVNFMNKMGEEAALKRPEIISTVTSFVHAACLVYIDGIGSGVTSSGFGTALLARKECLKFLIKRLAKIVRLTEYQKNELKIYDRMKAKEFTGIDNLWGIHPFFIPRGPVLHRNNIADYALSAGTTAMNAQRLLRATKLKKPILLEGSPGVGKTSLVGALAKASGNTLVRINLSEQTDITDLFGADLPVEGGKGGEFAWRDGPLLAALKAGHWVVLDELNLASQSVLEGLNACFDHRGEIYVPELGMSFQVQHEKTKIFGCQNPFRQGGGRKGLPRSFLNRFTQVFVDPLTVIDMEFIASTLFPAIEKNIVKKMVAFNNQIDHEVTVEKKWGQKGGPWEFNLRDLFRWCQLMLVDQSPGCYDPGQHVFLVYGERMRTEEDKKKVIAVFKDVFGSNSNPYMGTRLFRITPYDVQLGYSVLSRGSCVPHPSRHPLLLLHQSFQPLESIMKCVQMSWMVILVGPASVGKTSLVQLLAHLTGHTLKIMAMNSAMDTTELLGGFEQVDLIRPWRRLLEKVEGTVRALLRDSLLISADDAEVVLRAWSHFLLTYKPKCLGEGGKAITMEIVNKLEAVLLLMQRLNNKINSYCKAEFAKLVEEFRSFGVKLTQLASGHSHGTFEWVDSMLVQALKSGDWLLMDNVNFCNPSVLDRLNALLEPGGVLTISERGMIDGSTPTITPNPNFRLFLSMDPVHGDISRAMRNRGLEIYISGEGDASTPDNLDLKVLLHSLGLVGNSVCDILLALHTETRSTVVGSPTSSVSTLIQTAILIVQYLQRGLSLDRAFSEACWEVYVCSQHSPANRKLVQALLEKHVSSLRAHETWGDSILGMGLWPDSVPSALFATEDSHLSTVRRDGQILVYCLNRMSMKTSSWTRSQPFTLQDLEKIMQSPSPENLKFNAVEVNTYWIDEPDVLVMAVKLLIERATNQDWMLRVKWLYHLAKNIPQGLESIQIHLEASAASLRNFYSHSLSGAVSNVFKILQPNTTDEFVIPLDPRWNMQALDMIRNLMDFDPQTDQPDQLFALLESAANKTIIYLDREKRVFTEANLVSVGSKKLRESVLRMSFEFHQDPESYHTLPHEIVVNLAAFFELCDALVLLWVQSSQGMVSDASANEILGSLRWRDRFWTVADTVKVDAPGLALLALHWHWVLKHLVHQIPRLLMNYEDKYYKEVQTVSEHIQNCLGSQTGGFAGIKKLQKFLGRPFPFKDKLVVECFSQLKVLNKVLAIREQMSALGESGWQEDINRLQVVASQWTLKKSLLQAWGLILRANILEDVSLDELKNFVHAQCLELKAKGLSLGFLEKKHDEASSLSHPDLTSVIHLTRSVQLWPAMEYLAMLWRYKVTADFMAQACLRRCSKNQQPQINEEISHLISFCLYHTPVTPQELRDLWSLLHHQKVSPEEITSLWSELFNSMFMSFWSSTVTTNPEYWLMWNPLPGMQQREAPKSVLDSTLKGPGNLNRPIFSKCCFEVLTSSWRASPWDVSGLPILSSSHVTLGEWVERTQQLQDISSMLWTNMAISSVAEFRRTDSQLQGQVLFRHLAGLAELLPESRRQEYMQNCEQLLLGSSQAFQHVGQTLGDMAGQEVLPKELLCQLLTSLHHFVGEGESKRSLPEPAQRGSLWVSLGLLQIQTWLPQARFDPAVKREYKLNYVKEELHQLQCEWKTRNLSSQLQTGRDLEDEVVVSYSHPHVRLLRQRMDRLDNLTCHLLKKQAFRPQLPAYESLVQEIHHYVTSIAKAPAVQDLLTRLLQALHIDGPRSAQVAQSLLKEEASWQQSHHQFRKRLSEEYTFYPDAVSPLQASILQLQHGMRLVASELHTSLHSSMVGADRLGTLATALLAFPSVGPTFPTYYAHADTLCSVKSEEVLRGLGKLILKRSGGKELEGKGQKACPTREQLLMNALLYLRSHVLCKGELDQRALQLFRHVCQEIISEWDEQERIAQEKAEQESGLYRYRSRNSRTALSEEEEEEREFRKQFPLHEKDFADILVQPTLEENKGTSDGQEEEAGTNPALLSQNSMQAVMLIHQQLCLNFARSLWYQQTLPPHEAKHYLSLFLSCYQTGASLVTHFYPLMGVELNDRLLGSQLLACTLSHNTLFGEAPSDLMVKPDGPYDFYQHPNVPEARQCQPVLQGFSEAVSHLLQDWPEHPALEQLLVVMDRIRSFPLSSPISKFLNGLEILLAKAQDWEENASRALSLRKHLDLISQMIIRWRKLELNCWSMSLDNTMKRHTEKSTKHWFSIYQMLEKHMQEQTEEQEDDKQMTLMLLVSTLQAFIEGSSLGEFHVRLQMLLVFHCHVLLMPQVEGKDSLCSVLWNLYHYYKQFFDRVQAKIVELRSPLEKELKEFVKISKWNDVSFWSIKQSVEKTHRTLFKFMKKFEAVLSEPCRSSLVESDKEEQPDFLPRPTDGAASELSSIQNLNRALRETLLAQPAAGQATIPEWCQGAAPSGLEGELLRRLPKLRKRMRKMCLTFMKESPLPRLVEGLDQFTGEVISSVSELQSLKVEPSAEKEKQRSEAKHILMQKQRALSDLFKHLAKIGLSYRKGLAWARSKNPQEMLHLHPLDLQSALSIVSSTQEADSRLLTEISSSWDGCQKYFYRSLARHARLNAALATPAKEMGMGNVERCRGFSAHLMKMLVRQRRSLTTLSEQWIILRNLLSCVQEIHSRLMGPQAYPVAFPPQDGVQQWTERLQHLAMQCQILLEQLSWLLQCCPSVGPAPGHGNVQVLGQPPGPCLEGPELSKGQLCGVVLDLIPSNLSYPSPIPGSQLPSGCRMRKQDHLWQQSTTRLTEMLKTIKTVKADVDKIRQQSCETLFHSWKDFEVCSSALSCLSQVSVHLQGLESLFILPGMEVEQRDSQMALVESLEYVRGEISKAMADFTTWKTHLLTSDSQGGNQMLDEGFVEDFSEQMEIAIRAILCAIQNLEERKNEKAEENTDQASPQEDYAGFERLQSGHLTKLLEDDFWADVSTLHVQKIISAISELLERLKSYGEDGTAAKHLFFSQSCSLLVRLVPVLSSYSDLVLFFLTMSLATHRSTAKLLSVLAQVFTELAQKGFCLPKEFMEDSAGEGATEFHDYEGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKAHKETENEKPERSRESTIHTAHQFLMDTIFQPFLKDVNELRQELERQLEMWQPRESGNPEEEKVAAEMWQSYLILTAPLSQRLCEELRLILEPTQAAKLKGDYRTGKRLNIRKVIPYIASQFRKDKIWLRRTKPSKRQYQICLAIDDSSSMVDNHTKQLAFESLAVIGNALTLLEVGQIAVCSFGESVKLLHPFHEQFSDYSGSQILRLCKFQQKKTKIAQFLESVANMFAAAQQLSQNISSETAQLLLVVSDGRGLFLEGKERVLAAVQAARNANIFVIFVVLDNPSSRDSILDIKVPIFKGPGEMPEIRSYMEEFPFPYYIILRDVNALPETLSDALRQWFELVTASDHP", 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analysis of midasin, a novel and highly conserved AAA protein distantly related to dynein.", "journal": "BMC Genomics", "date": "2002", "authors": "Garbarino Joan E, Gibbons I R", "evidence": [ { "database": "UniProtKB", "id": "Q9NU22", "url": "https://www.uniprot.org/uniprotkb/Q9NU22" } ], "reference": [ { "type": "PubMed", "id": "12102729", "url": "https://glygen.org/publication/PubMed/12102729" } ] }, { "title": "Large-scale characterization of HeLa cell nuclear phosphoproteins.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2004", "authors": "Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villen J, Li J, Cohn MA, Cantley LC, Gygi SP", "evidence": [ { "database": "iPTMnet", "id": "Q9NU22", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9NU22" } ], "reference": [ { "type": "PubMed", "id": "15302935", "url": "https://glygen.org/publication/PubMed/15302935" } ] }, { "title": "Global, in vivo, and 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acetylation targets protein complexes and co-regulates major cellular functions.", "journal": "Science (New York, N.Y.)", "date": "2009", "authors": "Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M", "evidence": [ { "database": "UniProtKB", "id": "Q9NU22", "url": "https://www.uniprot.org/uniprotkb/Q9NU22" } ], "reference": [ { "type": "PubMed", "id": "19608861", "url": "https://glygen.org/publication/PubMed/19608861" } ] }, { "title": "Global effects of kinase inhibitors on signaling networks revealed by quantitative phosphoproteomics.", "journal": "Molecular & cellular proteomics : MCP", "date": "2009", "authors": "Pan C, Olsen JV, Daub H, Mann M", "evidence": [ { "database": "iPTMnet", "id": "Q9NU22", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9NU22" } ], "reference": [ { "type": "PubMed", "id": "19651622", "url": "https://glygen.org/publication/PubMed/19651622" } ] }, { "title": "Phosphoproteomic analysis of human embryonic stem 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of protein-protein interactions.", "journal": "Science signaling", "date": "2009", "authors": "Mayya V, Lundgren DH, Hwang SI, Rezaul K, Wu L, Eng JK, Rodionov V, Han DK", "evidence": [ { "database": "UniProtKB", "id": "Q9NU22", "url": "https://www.uniprot.org/uniprotkb/Q9NU22" }, { "database": "iPTMnet", "id": "Q9NU22", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9NU22" } ], "reference": [ { "type": "PubMed", "id": "19690332", "url": "https://glygen.org/publication/PubMed/19690332" } ] }, { "title": "Quantitative analysis of the human spindle phosphoproteome at distinct mitotic stages.", "journal": "Journal of proteome research", "date": "2009", "authors": "Malik R, Lenobel R, Santamaria A, Ries A, Nigg EA, Korner R", "evidence": [ { "database": "iPTMnet", "id": "Q9NU22", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9NU22" } ], "reference": [ { "type": "PubMed", "id": "19691289", "url": "https://glygen.org/publication/PubMed/19691289" } ] }, { "title": "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.", "journal": "Science signaling", "date": "2010", "authors": "Olsen JV, Vermeulen M, Santamaria A, Kumar C, Miller ML, Jensen LJ, Gnad F, Cox J, Jensen TS, Nigg EA, Brunak S, Mann M", "evidence": [ { "database": "UniProtKB", "id": "Q9NU22", "url": "https://www.uniprot.org/uniprotkb/Q9NU22" }, { "database": "iPTMnet", "id": "Q9NU22", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9NU22" } ], "reference": [ { "type": "PubMed", "id": "20068231", "url": "https://glygen.org/publication/PubMed/20068231" } ] }, { "title": "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.", "journal": "Science signaling", "date": "2011", "authors": "Rigbolt KT, Prokhorova TA, Akimov V, Henningsen J, Johansen PT, Kratchmarova I, Kassem M, Mann M, Olsen JV, Blagoev B", "evidence": [ { "database": "UniProtKB", "id": 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Cell. Proteomics", "date": "2012", "authors": "Ahmad Yasmeen, Boisvert Francois-Michel, Lundberg Emma, Uhlen Mathias, Lamond Angus I", "evidence": [ { "database": "UniProtKB", "id": "Q9NU22", "url": "https://www.uniprot.org/uniprotkb/Q9NU22" } ], "reference": [ { "type": "PubMed", "id": "22002106", "url": "https://glygen.org/publication/PubMed/22002106" } ] }, { "title": "Secreted HLA recapitulates the immunopeptidome and allows in-depth coverage of HLA A*02:01 ligands.", "journal": "Molecular immunology", "date": "2012-06", "authors": "Scull Katherine E, Dudek Nadine L, Corbett Alexandra J, Ramarathinam Sri H, Gorasia Dhana G, Williamson Nicholas A, Purcell Anthony W", "evidence": [ { "database": "IEDB", "id": "442359", "url": "https://www.iedb.org/epitope/442359" } ], "reference": [ { "type": "PubMed", "id": "22424782", "url": "https://glygen.org/publication/PubMed/22424782" } ] }, { "title": "Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire.", 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Arnoud H, van der Burg Sjoerd H, van Veelen Peter A, van Hall Thorbald", "evidence": [ { "database": "IEDB", "id": "434254", "url": "https://www.iedb.org/epitope/434254" }, { "database": "IEDB", "id": "445437", "url": "https://www.iedb.org/epitope/445437" } ], "reference": [ { "type": "PubMed", "id": "22898188", "url": "https://glygen.org/publication/PubMed/22898188" } ] }, { "title": "Toward a comprehensive characterization of a human cancer cell phosphoproteome.", "journal": "Journal of proteome research", "date": "2013", "authors": "Zhou H, Di Palma S, Preisinger C, Peng M, Polat AN, Heck AJ, Mohammed S", "evidence": [ { "database": "UniProtKB", "id": "Q9NU22", "url": "https://www.uniprot.org/uniprotkb/Q9NU22" }, { "database": "iPTMnet", "id": "Q9NU22", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9NU22" } ], "reference": [ { "type": "PubMed", "id": "23186163", "url": "https://glygen.org/publication/PubMed/23186163" } ] }, { "title": "The human leukocyte 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C\u00e9line M, Caron-Lizotte Olivier, Boucher Genevi\u00e8ve, Hardy Marie-Pierre, Gendron Patrick, C\u00f4t\u00e9 Caroline, Lemieux S\u00e9bastien, Thibault Pierre, Perreault Claude", "evidence": [ { "database": "IEDB", "id": "199115", "url": "https://www.iedb.org/epitope/199115" }, { "database": "IEDB", "id": "213334", "url": "https://www.iedb.org/epitope/213334" }, { "database": "IEDB", "id": "217492", "url": "https://www.iedb.org/epitope/217492" } ], "reference": [ { "type": "PubMed", "id": "24714562", "url": "https://glygen.org/publication/PubMed/24714562" } ] }, { "title": "The nature and extent of contributions by defective ribosome products to the HLA peptidome.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2014-04-22", "authors": "Bourdetsky Dmitry, Schmelzer Christian E H, Admon Arie", "evidence": [ { "database": "IEDB", "id": "213334", "url": "https://www.iedb.org/epitope/213334" }, { "database": "IEDB", "id": 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Chem.", "date": "2016", "authors": "Romes EM, Sobhany M, Stanley RE", "evidence": [ { "database": "UniProtKB", "id": "Q9NU22", "url": "https://www.uniprot.org/uniprotkb/Q9NU22" }, { "database": "RefSeq", "id": "NP_055426", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_055426" } ], "reference": [ { "type": "PubMed", "id": "26601951", "url": "https://glygen.org/publication/PubMed/26601951" } ] }, { "title": "Global proteogenomic analysis of human MHC class I-associated peptides derived from non-canonical reading frames.", "journal": "Nature communications", "date": "2016-01-05", "authors": "Laumont C\u00e9line M, Daouda Tariq, Laverdure Jean-Philippe, Bonneil \u00c9ric, Caron-Lizotte Olivier, Hardy Marie-Pierre, Granados Diana P, Durette Chantal, Lemieux S\u00e9bastien, Thibault Pierre, Perreault Claude", "evidence": [ { "database": "IEDB", "id": "199115", "url": "https://www.iedb.org/epitope/199115" }, { "database": "IEDB", "id": "217492", "url": "https://www.iedb.org/epitope/217492" } ], "reference": [ { "type": "PubMed", "id": "26728094", "url": "https://glygen.org/publication/PubMed/26728094" } ] }, { "title": "Viral infection causes a shift in the self peptide repertoire presented by human MHC class I molecules.", "journal": "Proteomics. Clinical applications", "date": "2015-12", "authors": "Spencer Charles T, Bezbradica Jelena S, Ramos Mireya G, Arico Chenoa D, Conant Stephanie B, Gilchuk Pavlo, Gray Jennifer J, Zheng Mu, Niu Xinnan, Hildebrand William, Link Andrew J, Joyce Sebastian", "evidence": [ { "database": "IEDB", "id": "163528", "url": "https://www.iedb.org/epitope/163528" }, { "database": "IEDB", "id": "440643", "url": "https://www.iedb.org/epitope/440643" }, { "database": "IEDB", "id": "445437", "url": "https://www.iedb.org/epitope/445437" }, { "database": "IEDB", "id": "462976", "url": "https://www.iedb.org/epitope/462976" }, { "database": "IEDB", "id": "471767", "url": "https://www.iedb.org/epitope/471767" } ], "reference": [ { "type": "PubMed", "id": "26768311", "url": "https://glygen.org/publication/PubMed/26768311" } ] }, { "title": "Comparative Analysis of the Endogenous Peptidomes Displayed by HLA-B*27 and Mamu-B*08: Two MHC Class I Alleles Associated with Elite Control of HIV/SIV Infection.", 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Hilke Franz J, Trautwein Nico, Kowalewski Daniel J, Schuster Heiko, G\u00fcnder Marc, Carcamo Ya\u00f1ez Viviana A, Mohr Christopher, Sturm Marc, Nguyen Huu-Phuc, Riess Olaf, Bauer Peter, Nahnsen Sven, Nadalin Silvio, Zieker Derek, Glatzle J\u00f6rg, Thiel Karolin, Schneiderhan-Marra Nicole, Clasen Stephan, B\u00f6sm\u00fcller Hans, Fend Falko, Kohlbacher Oliver, Gouttefangeas C\u00e9cile, Stevanovi\u0107 Stefan, K\u00f6nigsrainer Alfred, Rammensee Hans-Georg", "evidence": [ { "database": "IEDB", "id": "1313165", "url": "https://www.iedb.org/epitope/1313165" } ], "reference": [ { "type": "PubMed", "id": "27397612", "url": "https://glygen.org/publication/PubMed/27397612" } ] }, { "title": "Diverse HLA-I Peptide Repertoires of the APC Lines MUTZ3-Derived Immature and Mature Dendritic Cells and THP1-Derived Macrophages.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "2016-09-15", "authors": "Nyambura Lydon Wainaina, Jarmalavicius Saulius, Baleeiro Renato Brito, 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[ { "database": "IEDB", "id": "434254", "url": "https://www.iedb.org/epitope/434254" }, { "database": "IEDB", "id": "614884", "url": "https://www.iedb.org/epitope/614884" } ], "reference": [ { "type": "PubMed", "id": "36215666", "url": "https://glygen.org/publication/PubMed/36215666" } ] }, { "title": "Immunopeptidomics-based design of mRNA vaccine formulations against Listeria monocytogenes.", "journal": "Nature communications", "date": "2022-10-14", "authors": "Mayer Rupert L, Verbeke Rein, Asselman Caroline, Aernout Ilke, Gul Adillah, Eggermont Denzel, Boucher Katie, Thery Fabien, Maia Teresa M, Demol Hans, Gabriels Ralf, Martens Lennart, B\u00e9cavin Christophe, De Smedt Stefaan C, Vandekerckhove Bart, Lentacker Ine, Impens Francis", "evidence": [ { "database": "IEDB", "id": "434254", "url": "https://www.iedb.org/epitope/434254" }, { "database": "IEDB", "id": "442359", "url": "https://www.iedb.org/epitope/442359" }, { "database": "IEDB", "id": "459027", "url": "https://www.iedb.org/epitope/459027" }, { "database": "IEDB", "id": "471767", "url": "https://www.iedb.org/epitope/471767" }, { "database": "IEDB", "id": "477387", "url": "https://www.iedb.org/epitope/477387" }, { "database": "IEDB", "id": "614884", "url": "https://www.iedb.org/epitope/614884" }, { "database": "IEDB", "id": "628614", "url": "https://www.iedb.org/epitope/628614" }, { "database": "IEDB", "id": "632127", "url": "https://www.iedb.org/epitope/632127" }, { "database": "IEDB", "id": "649209", "url": "https://www.iedb.org/epitope/649209" }, { "database": "IEDB", "id": "877962", "url": "https://www.iedb.org/epitope/877962" }, { "database": "IEDB", "id": "1203359", "url": "https://www.iedb.org/epitope/1203359" }, { "database": "IEDB", "id": "2010998", "url": "https://www.iedb.org/epitope/2010998" }, { "database": "IEDB", "id": "2244628", "url": "https://www.iedb.org/epitope/2244628" }, { "database": "IEDB", "id": "2244962", "url": "https://www.iedb.org/epitope/2244962" }, { "database": "IEDB", "id": "2246599", "url": "https://www.iedb.org/epitope/2246599" } ], "reference": [ { "type": "PubMed", "id": "36241641", "url": "https://glygen.org/publication/PubMed/36241641" } ] }, { "title": "Direct identification of HLA class I and class II-restricted T cell epitopes in pancreatic cancer tissues by mass spectrometry.", "journal": "Journal of hematology & oncology", "date": "2022-10-25", "authors": "Fujiwara Kenji, Shao Yingkuan, Niu Nan, Zhang Tengyi, Herbst Brian, Henderson Mackenzie, Muth Stephen, Zhang Pingbo, Zheng Lei", "evidence": [ { "database": "IEDB", "id": "163528", "url": "https://www.iedb.org/epitope/163528" }, { "database": "IEDB", "id": "596320", "url": "https://www.iedb.org/epitope/596320" } ], "reference": [ { "type": "PubMed", "id": "36284347", "url": "https://glygen.org/publication/PubMed/36284347" } ] }, { "title": "Extracellular arginine availability modulates eIF2\u03b1 O-GlcNAcylation and heme oxygenase 1 translation for cellular homeostasis.", "journal": "Journal of biomedical science", "date": "2023-05-22", "authors": "Hung Yu-Wen, Ouyang Ching, Ping Xiaoli, Qi Yue, Wang Yi-Chang, Kung Hsing-Jien, Ann David K", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9NU22", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9NU22" } ], "reference": [ { "type": "PubMed", "id": "37217939", "url": "https://glygen.org/publication/PubMed/37217939" } ] }, { "title": "Targeting of intracellular oncoproteins with peptide-centric CARs.", "journal": "Nature", "date": "2023-11", "authors": "Yarmarkovich Mark, Marshall Quinlen F, Warrington John M, Premaratne Rasika, Farrel Alvin, Groff David, Li Wei, di Marco Moreno, Runbeck Erin, Truong Hau, Toor Jugmohit S, Tripathi Sarvind, Nguyen Son, Shen Helena, Noel Tiffany, Church Nicole L, Weiner Amber, Kendsersky Nathan, Martinez Dan, Weisberg Rebecca, Christie Molly, Eisenlohr Laurence, Bosse Kristopher R, Dimitrov Dimiter S, Stevanovic Stefan, Sgourakis Nikolaos G, Kiefel Ben R, Maris John M", "evidence": [ { "database": "IEDB", "id": "213334", "url": "https://www.iedb.org/epitope/213334" }, { "database": "IEDB", "id": "440643", "url": "https://www.iedb.org/epitope/440643" }, { "database": "IEDB", "id": "877962", "url": "https://www.iedb.org/epitope/877962" }, { "database": "IEDB", "id": "935482", "url": "https://www.iedb.org/epitope/935482" }, { "database": "IEDB", "id": "1062712", "url": "https://www.iedb.org/epitope/1062712" } ], "reference": [ { "type": "PubMed", "id": "37938771", "url": "https://glygen.org/publication/PubMed/37938771" } ] }, { "title": "Studying the O-GlcNAcome of human placentas using banked tissue samples.", "journal": "Glycobiology", "date": "2024-01-22", "authors": "Luna Sarai, Malard Florian, Pereckas Michaela, Aoki Mayumi, Aoki Kazahiro, Olivier-Van Stichelen Stephanie", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9NU22", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9NU22" } ], "reference": [ { "type": "PubMed", "id": "38253038", "url": "https://glygen.org/publication/PubMed/38253038" } ] }, { "title": "DNA probe pulldown screening uncovers O-GlcNAcylation modulation of transcription factor DNA interactions.", "journal": "Scientific reports", "date": "2025-07-02", "authors": "Li Guofang, Meng Fanxu, Zhong Xiaomin, Yu Kairan, Zhang Nana, Zhang Keren, Huang Huang, Li Wenli, Zhang Jianing, Wang Wei, Ren Yan, Liu Yubo", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q9NU22", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q9NU22" } ], "reference": [ { "type": "PubMed", "id": "40596516", "url": "https://glygen.org/publication/PubMed/40596516" } ] } ], "pathway": [ { "id": "hsa:23195", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?hsa:23195", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K9L9-1", "protein_name": "Midasin", "gene_name": "Mdn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEHLSVDLVAGPLRLIATKNEKSSGELNRFLAKSVWTPQDRQCILNSLAQLLLDKDYTLLLGRQLRPILLDLLERNAKAIKTGGQVNHDLHERLSVSMSKLIGSHPDVLPFALRYFKDTYPVFQRLFLESSDANPVRYGRRRMKLRDLMEAAHIFLQHKQPVFRELWDWSVCVPLLRSHDALVRWHTANCLALVTCMNEEHKLSFLRKIFSSEELVHFRLRLLEEAQLQDLEKALVLANPEASLWHKGEEPQYIQGHLVSADLSSSVAAVCGVVLPKQSSSPAEQQTSDRSSSRDQELALTSFVLVESVCKNLQMLAVAVASQNAVLLEGPIGSGKTSLVEHLAAVTGRTKPPQLLKVQLGDQTDSKMLLGMYRCTDVPGEFVWQPGTLTQAATKGHWILLEDIDYAPLDVVSVLIPLLENGELLIPGQGDCLKVAPTFQLFATRRLLSCGGSWYRPLNSHAAMLDKYWTKIHLHNLDKKDLREVLQNRYPSLLTATDHLLDIYIELTGEKHCCPSIGCDEAPQEVSEAEGENRRVALEGRELSLRDLLNWCNRVAHGFDSTSSTALLNVFQEALDCFTAMLSEQTKKLKMAEIIGSKLNISKKKAEFFCKLYKPEIVINELDVQVGRVRLLRKQSEVVRIQKEKCSFAATRPSSVLLEQLAVCVSQGEPVLLVGETGTGKTSAVQHLAHATGQHLRVVNMNQQSDTADLLGGFKPVDHKLIWLPLRETFEELFVQTFSKKQNFTFLGHIQTCYRQKRWHDLLKLMQHVQKSAITKEGKESQPGLLLKEKWEAFGLRLNHAQQQMKMTENALLFAFVEGTLAQAIKKGEWILLDEINLAAPETLECLSGLLEGSSGSLVLLDRGDTEPLVRHPDFRLFACMNPATDVGKRNLPPGIRNRFTELYVEELESKEDLHILIVDYLKGLSVSRSAVQGIVNFYTALRKESKTKLVDGTGHRPHYSLRTLCRALRFAASNPCGNIQRSLYEGFCLGFLTQLDRASHPVVQKLICQHIISGNVKSLLKQPIPEPKGGRLIQVEGYWISVGDKEPKIDETYVLTPSVKLNLRDIARVVSAGTYPVLIQGETSVGKTSLIRWLAAATGNHCVRINNHEHTDIQEYIGCYTSDTSGKLVFNEGVLIDAMRKGYWIVLDELNLAPTDVLEALNRLLDDNRELLITETQEVVRAHPRFMLFATQNPPGLYGGRKVLSRAFRNRFVELHFDELPSSELETILHKRCSLPPSYCSKLVKVMLELQSYRRRSSVFAGKQGFIALRDLFRWAERYRLAEQTEKDYDWLQHLANDGFMLLAGRVRKQEEADVIQEVLEKHFKKKLCPQSLFSKENVLKLLSKSSTQTSVLESKFSHVVWTEGMRRLAVLVGRALEFGEPVLLVGDTGCGKTTVCQLFSALSNQKLYSVNCHLNMETSDFLGGLRPVRQKPNDKEEPDTRLFEWHDGPLVLAMKEDSFFLLDEISLADDSVLERLNSVLEVEKCLVLAEKGSPESKDTEVELLTAGKHFRILATMNPGGDFGKKELSPALRNRFTEIWCPQSTKREDLVQIINHNLRPGLSLARAGHKGADIAEVMLDFITWLTHQEFGRKCVVSIRDILSWVNFMNTMAEEAAVKRLETISTVTSFVHAACLVYIDGIGSGVTSSGFGTALLAREECLKFLIKKLSKVVRLTERQKDELKIYDRLKHKEFTSVDDLWGVHPFFIPRGPVLNGHTIADYALSAGTTAMNAQRLLRAAKLNKPILLEGSPGVGKTSLVAALAKASGNTLVRINLSEQTDITDLFGADLPVEGGKGGEFAWCDGPLLAALKAGHWVVLDELNLASQSILEGLNACFDHRGEIYVPELGMSFQVQHEKTRIFGCQNPFRQGGGRKGLPKSFLNRFTQVFVDPLTVVDMEFIASTLFPAIDRNIVKKMVAFNNHIDHEVTVEKKWGQKGGPWEFNLRDLFRWCQLMLVDQSPGCYDPGQHVFLIYGERMRTREDKEKVITVFKDVFASNSMPYIGTRLFHITPYDVQIGYSVLSRSSYVPHPSRRPLSLLHQSLQSLEPIMKCVQMSWMVILVGPASVGKTSLVQLLAHLTGHTLKIMAMNSAMDTTELLGGFEQVDIIRPWRLLLEKVERAVRVLLRDSLLINADDTEVVLRAWSHFLLTYRPKCLGEDGKGVTIEIVNKLEAVLLLLQRLNNKINSYSKADFAKLVEDFRTFGVKLLQSTSGRSHGSFEWVDSMLVQALKSGDWLLMDNVNFCNPSVLDRLNALLEPGGVLTINERGMVDGSTCTVTPNPNFRLFLSMDPVHGEISRAMRNRGLEIYISEEKEGSILENLDLKVLLHSLGLVGDSLCNVLLALHTGVQSLVKGSPTSSVSTLSHTAILIVQYLQRGLSLDKAFFEACWEVYVCSQHSAANQKLVQALLESHTASLRAKETWGHSILATGLWPDSVPSALFATEDSRLAVVRSDGQILAYCLNRLSLRTISWTRSQPLTLQDLEHIMQTSNPENLTFNAVEVDTCWVDEPEVLAMAVKLLIERATNQDWMLRVKWLSHLAKNIPQGLEAVRSHVEASATALRKFYAASLSAGVSNVLKILQTNITDDFVIPWDPRWNMQALDIIRNSLDFDPQSDQAEQLFELLESVANKTIIYLDREKRIFTEANLLSVGSKKLRSNALRMSFEFHKDPETYHSPPHEIVANLAAFFELIDGLILLWVQSPQGMVPDAHVNKILGSMQWRDRFWAVADAVTVDASGLALLALHWHWVSKHLIRQIPQLLVNHEDKYYKEVQMVSEQIHSCLGSPAGSFPGVKKLQAFLGRPFPFKDKLVVDCFSQLQALNRALSIGERLPVFGECGWQEDINRLQVVASEWNLKKSLLQTWGLILRANILEDVNLDELKNLVNTQCSELKTRGLSHGFLEKAHEASSPSQPDLSSLAHLTRRVQLWPVTEYLAVLWQYRVTAGFVTQACLRRSSTHQQMDEEISHCITFCLKHTPIAPQKLWNLWSLLHIQKLSAQEVSCLWSELFTSTFGSSWSSPVTTNPEYWLTWSPLPNAQPQEMPRSRWDSTLKGPGSLCRAVFSKCCFGVLTNSSSGSSWDVSGLPLLSSSHVTLGEWVERAQQLQDIRSLLWTNMTVPSVAEFRRTDSRLQGLVLCRYLLGLTELLPAPQRQEYMQNCEHLLLGNTQAFHHVDQTLANIGGQEVLPKELFCLLLTSLHYFIGEGESKQNLREAARRGRLWVSLGLLQIQTWVPQTRFDPAVKKAYKLKYAQEELCQLQCELKTRNLLSHLQTGRDLEDDIIASHSHPHIRLLPQRISHLENLVHSLSKKQAFRPHLPSYETLVQEIHHYVTSIAKVTAVQDLLMRLLQALHTDGPKSAQVLQNLLKEEASWQQSHQQFRKRLVEEYALYPDTVTPLQASILQLQHGMRLVASEVHASLHSSVICTEHVEALAMAVLAFPSVGPSFPTYHAHADALCSVNSAEALRGLGKLMVKRAARKEEGKNQQPYPTREQLLMNALLYLRSHVLCKGELDQRALLLFRHLCQEIINEWDEQERIAQEKAEQESSLYRCRSRSCRTALSEEEEDELELRKLFPLHEKDFADILMEPTLEEKRRASDGREEAATDPALLSQSSMQAVMLIHQQLCLSFARSLWYQQSVPAHEAEHYLSLFFSCYQTGASLLTHFYHLMGVEMNDQLLGSQLLACTLSSNTLCGEATSDLMMKPDGPYDFYQHPNVAEARQCQPVLQGLSEAVSQLLQDWPEHPVLEQLLVVMDRIRGFPLSSPISKLLNGLEILLAKAQDWEENASRELSLRKHLDLVSQMIIRWRKLELNCWSMSLDNTMRRHTEKSTKHWFSIYQMLEKHMQERTEEQEDDKPMTLMLLVSTLQAFIEGSSLGEFHVRLQMLLVFHCHVLLMPQVEGKDSLCSVLWNLYHFYKQFLDPVQAKIVELRSPIEKELKEFVKISKWNDVSFWSIKQSVEKTHRTLFKFMKKFEAVLNEPCQSCLVESNKEEQPDCLPKPTEEATMETSPIQALNSALRETLLAQPIAWQPSGTEQCQDAVGPLSMEGELLRRLPRLSKRMRKVCLIFMKESPLPHLVESLDQFTGGVISSVSELQSLTVDPSAEKEKQHSEAKHILMQKHRALSDLFKHLAKIGLSYRKGLAWARSKSPQELLHLHPLDLQSALSIVSSTREADSRLLTEISSLWDGCQKYFYRSLARLTRLTAALATPAKEISMGNVDRCKGFSAHLMKLLIRQRHSLTTLTEQWIILRNLLSCVQEIHSRLIGPPVYPVAFPPQDSVQQWTERLQHLAMQSQILLEQFSWLLQCCPSVGPTEGHSDAPFQEHPSASHLEKVDTKGPIAGAMPDLLPSALSYPSPVPRSQLPSGCRMRRQDQLWQQSTAGLTEMLKTIKTMKAGVDKIRQQSCETLFHTWEDFEVCSSGLNCLSQVSAHLQGLASLFILPGIEVEKTDSQMALVESLDYLRGEISKAVDDFTAWKARLFIAHKQGGNQMLEESFVEDFSEQVESAIRAILCTIQNLAERNSKKAEDSAADKRLQEEDGGKEEEASFKSLQPGHLTKLLEDDFWASVSTLHVQKIISSVSELLERLKSCSEDGNTTKHKVFSQSCGLLVRLIPMLCGFSDLILFFLTISLATHRSTAKLLSVLTQTFTELALKGFCLPKELIEDSAGEGAMQFHDYEGGGIGDGEGVKDVSDRIENEEQVEDTFQKGQEKDKEDLDSKPDTKGEDSAVEMSEDFDGKMHDGELEQEEDDEKSDSEDGDLDKQMGNLNGEEADKLDERLWGDDEEEDEDDDGKGEEAGPGMDEEDSELVAKDDNLDAGNLNKNKKHQGEEEDSEPEDVEQGQEKINEQMDEREYDESEVDPYHGSQEQLPEPEALDLPDDLKLDSEDRSAGEDTDNEEAEEENPLEIKEKTVDMEEIDREVEEPDAAQSEGERPPAPDEGPGEGEESMDTGADDQDKDTASHAEEQEEEEEGEEGEEEEEEEDRAATDGSGESGVSPVDKDLQPQKEEEEGEKSDAEEQVPEATERKEHDSCGQTGVDNVQSAQAVELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIARLSSQQHTNKNTQSFKRRPGQADNERSIGDPNEHVRKRLRTVDTDRKTEQEPAQPQAQVEDADTFEHIQQGSDAYDAQTYDVASSEQQQTTKASGEDQEEEEKEDILMDTEEELIRAEDTEQLKPEAVRSETATASGSSEMEVDMQTLKTKEDEDPRTTTSHQEIESERPERSRESTIHTLHQLLVDTVFQPFLKDISELRQEMERQLETWQTHNYGNAEEEKAAAEMWQNYLVLTAALSQQLCEQLRLLLEPTQAAKLRGDYRTGKRLNMRKIIPYIASQFRKDRIWLRRTKPSKRQYQICLAIDDSSSMVDNHTKQLAFESLAVIGNALTLLEVGQIAVCSFGESVKLLHPFHEQFNDSSGSQILRLCKFQQRKTKIAQFLESVAIMFAAAQKLSQNTSPETAQLLLIVSDGRGLFLEGKDRVLAAVQAAQNANIFVIFVVLDNPNSRDSILDIKVPIFKGPGEMPEIRSYMEEFPFPFYIILRDVNALPETLSDALRQWFELVTASDHS", "length": 5589 }, "evidence": [ { "id": "MGI:1926159", "url": "https://alliancegenome.org/gene/MGI:1926159#orthology", "database": "AGR" }, { "id": "HGNC:18302", "url": "https://alliancegenome.org/gene/HGNC:18302#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041001-138", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041001-138#orthology", "database": "AGR" }, { "id": "FB:FBgn0033661", "url": "https://alliancegenome.org/gene/FB:FBgn0033661#orthology", "database": "AGR" }, { "id": "RGD:1306394", "url": "https://alliancegenome.org/gene/RGD:1306394#orthology", "database": "AGR" }, { "id": "SGD:S000004096", "url": "https://alliancegenome.org/gene/SGD:S000004096#orthology", "database": "AGR" }, { "id": "Q9NU22", "url": "https://omabrowser.org/oma/group/Q9NU22/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A1P8AUY4-1", "protein_name": "Midasin", "gene_name": "MDN1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAIDGSFNLKLALETFSVRCPKVAAFPCFTSILSKGGEVVDNEEVIHALGDAFLHPEFTVPLVHCFLPIIRNVVDRVVGLLRLVDDLKSSIDYSDDVSSVLDNAMTEGISVIDFYVRRGQRLELHECACLAFSRALHFNTSLLGSILNYFEKAPPPYERILVKDIVSESRMEATDAYLLCLRVSYRFLVIRPEVFSKLWDWSCYLDSMKRLSECPRQQRHFLEKYRDAVWCGIQILSVVLRCSDRLAGCFGFEEEEALSCLLRWEEFCQDIEIEKAGLYIQLPTYTALKSLQQFNTLVPGINKRQSAGLEADEPQMKIRRLDTWDVNSFSEPFEIHSRVKKSFEMVSLAVSQKRPVLLYGPSGSGKSALIRKLADESGNHVVFIHMDDQLDGKTLVGTYVCTDQPGEFRWQPGSLTQAIMNGFWVVLEDIDKAPSDVPLVLSSLLGGSCSFLTSQGEEIRIAETFQLFSTISTPECSVSHIRDAGNSLSPLWRRIVVYPPDRESLQSILGARYPNLGPVAEKLIETFETINSALRPQFSSSTTENSATFSSPSRFSLRDLLKWCERVHGLPSYDGHAVYQEAADIFSASNMSVKNRVAVSEIVASIWNVAVPESQDKPPIQEFSGILKIGRVSLPLGETASHDRSRFVETRTSTRLLEKIARSVEYNEPVLLVGETGTGKTTLVQNLAHWIGQKLTVLNLSQQSDIVDLLGGFKPIDPKLMCTMVYNEFNELARDLKIKDDSKIMKWLQDNFRAKKWHTFLTGLLDIIKGIEGRITERMEGKIGEARSRSGRKRKKPEEELKNCACLRTKVNKIRQQIHSGGMVFTFVEGAFVTALREGHWVLLDEVNLAPPEILGRLIGVLEGVRGSLCLAERGDVMGIPRHLNFRLFACMNPATDAGKRDLPFSFRSRFTEYAVDDDICDDDLEIFVRRFLGGRGSDSKLVANIVWFYKEAKRLSEESLQDGANQKPQYSLRSLYRALEYAIKAEAIGGFQKALYDGFSMFFLSLLDASSAKIVEPIIKRISGENIRSQPLQRYLGELKGSSDKFVGSYVKTKSVIDHLNHLAHAIFIKRYPVLLQGPTSSGKTSLVKYLAAISGNKFVRINNHEQTDIQEYLGSYMTDSSGKLVFHEGALVKAVRGGHWIVLDELNLAPSDVLEALNRLLDDNRELFVPELSETISAHPNFMLFATQNPPTLYGGRKILSRAFRNRFVEIHVDEIPEDELSEILTTKCSIANSHASKMVEVMKDLQRNRQSSKAFAGKHGYITPRDLFRWAYRFRTYDGTSHEELAREGYYILAERLRDDTEKVVVQEVLERHFRVSLAKDDLYNMELPRLDSIQNRKFTWTQSMRRLFFLIDRSYKLREPVLLVGDTGGGKTTICQILSDVKKKRLHILNCHQYTETSDFLGGFFPVRDRSKLITEYENQVKQLELSQALTPFGQDIVICGDISRAEVSIKSVEVALEKYKNGSVIGVAATPQDVDFLEKIRNNMVMLYQKWRAIFVWQDGPLVEAMRAGNIVLVDEISLADDSVLERMNSVLETDRKLSLAEKGGPVLEEVVAHEDFFVLATMNPGGDYGKKELSPALRNRFTEIWVPPITDTEELRSIAFSGLSSLKESNVVDPIINFWEWFNRLHTGRTLTVRDLLSWVAFVNMATESLGPAYAILHGAFLVLLDGLSLGTGFSGRDGQDLREKCFAFLLQQLELFASDTLPLELSRMELYGWGDSKAICEKSKSVRHEGMFGIDPFFISKGDENPEIGGFEFLAPTTHRNVLRVLRAMQLSKPILLEGSPGVGKTSLILALGKYSGHKVVRINLSEQTDMMDLLGSDLPVESDEDMKFAWSDGILLQALKEGSWVLLDELNLAPQSVLEGLNAILDHRAQVFIPELGCTFECPPTFRVFACQNPSTQGGGRKGLPKSFLNRFTKVYVDELVEDDYLFICRSLYPSVPSPLLSKLIALNRQLHDGTMLYRKFGHDGSPWEFNLRDVIRSCQFMQEAIHDLEVESFLNVLYIQRMRTATDRKEVLRIYKAIFDKTPSINPYPRVQLNPAYLVVGTAAIKRNLNQSNIASEQLKLLPEIRQNLEAVAHCVQNKWLCILVGPSSSGKTSVIRILAQLTGYPLNELNLSSATDSSDLLGCFEQYNAFRNFRLVMTRVEHLVDEYNSLLLQSSQEALFSNRSGLVSRWLSYLNKIDSSLVENPLFFLNDSETLSTLEEVVEDLEQVLKEGVLPVSWSKKYLEQISKTILQLQTHEKKQSTKFEWVTGMLIKAIEKGEWVVLKNANLCNPTVLDRINSLVEPCGSITINECGIVNGEPVTVVPHPNFRLFLSVNPKFGEVSRAMRNRGVEVFMMGPHWQLNEDGSNCEELVLRGVERFLALSGIPGYKLVTSMAKAHVHAWLNGQSFGVRITYLELEQWVHLFQLLLMNGNQLLWSLQLSWEHIYLSSLGVTDGKEVVDFVRETYLSDVELSELDSFMGGDLYLPGGWPKPFNLRDLTWYSRETTVRQNCMYLEFLGAQYASHQPKISDNVKSRDRELAAGEPRIIYSIDSWTLKKVLFPKALIGSSCAPDAANFENDLASKMLLFAANWTIEQATEEDIQLYLAWFSWFGSRLQQHCPFLLCFLNTLKVEFEHPIWNHISRCRKNLKFLCRLDPDAVPIPMLSSKLIDVAASNDQSKPYSKSLFESLNSVGVLRRSYQQWLVESNDNHTDVSTFTRFLDSLRVLEKKILCEIVGAPSFSVLIQLYTEVIDNHSFFWSGLVSSSDEYLLFSFWSLIKSIKKMHSFFPGEVQVVLEESKNINNIVLHGHPEKSMLWAYGGHPSLPVSAELFHKQQEFLQLCSTVWPLKSESDEHGNDHLTKAIPFSGPELCLLALEGLCISSYIADEDDVDYVAAVQLDEIYQTFLERLKLEKKRLEDKMGFSEIDNTENITASCCVFCPEIVTTGSGFSSWVKTCFIASSESCSLDVELLAALQHLLVARPTEHQDLVDIRKLLKPALEYSLSSTRPPQTLVAHQKLLWAIDAHASELGVDTKIAGFALEIWYWWHSVLWKNSQIGLMNISDTGNCQILSPSMLIQPVKTATVAQILENVFSVKDYSVQSMKLLSASRYLWKSSQPYQEMPGSLLSIARSLFQQIIYTHQKSFESETFVAIKSVFHAIEKKQNKMDGIQNLISLIGSSSHNKLKSVTHSFVGPLAKRLYSDSSSNALCPTFVEFYCNLGLAWLYLGGLRFHLLNSLDVIDPAMKITCKLLKLEEKISSLELNIKVRGECGYLSGLLYSGNNDESSEHTLSKLKTEHKRLQRKVIFRSDPKKYQDLRRALDEFAGFLTRPISLVNDIEVLDWNQVVEQVFNWQETAISFIDRMSSDYSEYVDITQPIQVSVYEMKLGLSLFVSGALLGKLLNRFDIDMVDSVMETIYALMRFPRDSSIASTTYTECLPPLHLSHGANSRAKSLGLDVGLLHKLISVSSAEDSRKASELQLKVALYKNLHARVLQFVANTGLLDEASFELLDKIYVELARIWMEMKFQAKTKADNLPGLYKFRSRDFKIDSVMEVDISALGKYFPNESFSEWQEYLADDDTKNVKDMTHIDQDEENLEDDWDLIQEHLDSIYSTHNELFGFCDLSEKSGRFCITDSRRLDSFTDSYELGVSMIKGLRGLFTSSLDAKLVPEHLLRLCLENKKNFTSNYQSASKYNFYKDLDGPELGKMVKFLTPLQQRINSLLQEREDHPGLQKLSGVLQMLLAIPSSTPLAKALSGLQFLLCKVHKLQEEGCKLPISDLLEPIISLASSWQKVEFERWPTLLDEVQDQYELNARKLWLPLFSVLFQKDAVEISEHENESISQSLVEFIETSNVGEFRRRLQLLFCFLLQLSMGSSLGIYSSDSHKRRVEMCYNIFGFYIQFLPVVMEQLDLNRKNVETELKEVLKLCRWERPDNYLYNETTKRTRQKVKKLIQKFTDMLRLPVMLVKPDLTKERAQFLPLLDPDLMDGASDMRIEVLVSALDAEQLRDRSSWYVVWWNKLKESVGRFHQEMHYKTLLMGAEHQYSSPVYQGDWKNLWSTVARIGETIAGCSDLWRNSDRDVAKKRALFELLKLLESSGLQKHKFENIEMSNHFKGLLYQPAYDPKHLLLLTHTKSNIHPSMGVEDQNKENSLVEWRVANEFYFKSLASVQLMLNIDRKHSDVTAEQVKRAISFLNHLVEIQRQQRKSAYAFAELFNRFRQCVLSLARLLGDSVGADRKDDSVFSFPQNQHAVFNCLWLQKQLFDNITAMLLEESALLRTVGSTHLDSCQAVKTSSRSLLSFIEILIPIAQNSKASLDRLLLDCNGFIITPSSSLKQFVTQHMVQVLRQNFDQLTDLENQISSFCENNEKSYCRDVLLSQFSPVFKEGKLLAENLNCLLNVRDQSTGMEPKERLFLEENLASIFANVKDVIGKLCSYKDGSLSQEEEMNITTWDGLFKKAENDLNLDNLCKLLSESFGSIEQLLNSSGVLSAGVGDQLKQLQAFLDLLLSFGDCYLKEFLAISKTVSLITHVLASVLADLFTKGFGISKNEEDDDSKVDKSEAAEGTGMGDGVGAKDVSDQIEDEDQLHGTDKKEEEEKEQDDVLGKNKGIEMSDEFDGKEYSVSEDEEEDKEDEGSEDEPLDNGIGDVGSDAEKADEKPWNKDEEDEEENMNEKNESGPSIVDKDTRSRELRAKDDGVETADEPEESNTSDKPEEGNDENVEQDDFDDTDNLEEKIQTKEEALGGLTPDVDNEQIDDDMEMDKTEEVEKEDANQQEEPCSEDQKHPEEGENDQEETQEPSEENMEAEAEDRCGSPQKEEPGNDLEQEPETEPIEGKEVMSEDMMKPNFRNDNISGVESGSQNPHGSNVLGAGSTAPQENLSATDVTDELTDSMDLPSSSNTEMNLMMTNMANGETLTDNLPKMEFPQNQSSTAQQTKVNPYRNVGDALKEWKERVRISSDLGEKQEAENEMEDPDASEYGFASQFDAGTSQALGPALPEQVNTDMREGESEEEKLAGNQDDVSPMDIDDLNPENKPAVQSKPSISNSIAEQVQEPDTDRTHQENSPIHNFGDGNSRMDSMVSVDNTFLGEEACNLDRMQVTDNDSESNQDNQEDPDARSNAVVLWRRCELLTAKPSQELAEQLRLILEPTLASKLSGDYRTGKRINMKKVIPYIASHYRKDKIWLRRTKPNKRDYQVVIAVDDSRSMSESGCGDFAIRALATVCRAMSQLELGSLAVASFGKQGSIKMLHDFGQSFTTESGIKMISNLTFKQENLIEDQPVVNLLRNMNEMLENLASTRRQSYGSNPLQQLVLIIGDGKFHEREKLKRTVRSFLQQKRMVVYLLLDDAEQSVFDLADYVYDGERRPYKKMNYLDSFPFPYYIVLRDIEALPRTLGDVLRQWFELMQSSRD", "length": 5400 }, "evidence": [ { "id": "Q9NU22", "url": "https://omabrowser.org/oma/group/Q9NU22/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A8M1RP38-1", "protein_name": "Midasin", "gene_name": "mdn1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MENLELSLTSLGAISRHIDKSQNELSKYLAKQIWSQQDRQCILECLAQLLLEKEYTLLIARHLRPLILDLLERNAERIKADIRLNHDLHERLCVALSKLLNISPDAQVFAARYFSSSPPVFQRLFFTSEEAASIQYGPRRMKLRDLMGATLRFLQSDCEKFRVLWDWSACVSQLLTSDVMVRSYTAQCLALVSHMTDNQKTIFLRKVLSSEEILHLKMKSLEEVQQLEVEKALVLANQGSAIWRKERVKKVTSGQVVTEDLTKSVTVVCGVILPRRTPRQDEQKCLRNLVLVDSTCQNLRRLAMAVASQKPILLEGPIGCGKTALVEYLAAVTGHVKAPDILKVQLGDQTDSKMLLGMYRCTDVPGKFVWQPGSLTQAVSKGYWILLEDIDHAPLDVISVLLPLMENKKLTIPGREDCIQMSPAFQFFATRRTFYSGGAWHRPQNTHAALLDKYWSKLQISNMSREELTQVLIKRFPNLAVVVDRLLDIYCQLTGNRHQINSSSQGPSAAQSISDDHITSLEGRGLSLRDLLKWCERICLNFESSCASTAQNVFQEALDCFTAMLSKSESRLKMAEIIGSRLNISKEKAQHFCQMYLPAITVTELEVTVGRAMLLRKQSDAVRLSIDRQTFAATRPSSVLLEQLSVCVTKGEPILLVGETGTGKTSTVQYLAGLTGHRLRVVNMNQQSDTADLLGGYKPVDHKLILLPLREAFEDLFSQTYSRKQNLTFLGHVQTCFRGKRWQDLLKLMDHVCKSALTKELHDKPNAALLQEQWEALALKLSQTQEQIRACESAMVFAFVEGTLAQAVKKGEWILLDEINLAAAETLECLSGLLEGSSGSLVLLDRGDTEPLFRHSDFRLFACMNPATDVGKRNLPLGIRNRFTELYVEELESESDLRILVSDYLKGLNLSRGIIHGIISFYLAVRKEANTRLVDGTGHKPHYSLRTLCRALKFVASDPCYNIQRSLYEGFCLSFLTQLDRSSHPIVQKLVCQYILGGNVKCLRQPIPQPKDRVCVQIDEYWLSQGDKEPAVDPSYILTPSVKLNLKDLARVVAAGIHPVLLQGETSVGKTSLIKWLAASTGNQCVRINNHEHTDIQEYIGCYSSDEHGKLVFKEGVLIDAMRKGYWIILDELNLAPTDVLEALNRLLDDNRELFVAETQEVVKAHPRFMLFATQNPPGLYGGRKVLSRAFRNRFVELHFNELPSSELENILHQRCSLPPSYCSKLIKVMQDLQSLRRGSSVFAGKHGYITLRDLFRWAERYRLEEQSESSRDWLQHLADDGYMLLAGRVRKPEEAVTIQNILEKHFKKTVNPDALFSEGQVTSQFSPFVNSIAGVPEEFGHVVWTQGMRRLAVLVGRALRFGESVLLVGDTGCGKTTICQLFAALAGQKFFSLNCHLHMETSDFLGGLRPVRHTGTQQADAEDGRLFEWHDGPLILAMKQDGVFLMDEISLADDSVLERLNSVLEPEKSLVLAEKGSGDEEVELIIAGNKFRLVATMNPGGDFGKKELSPALRNRFTEIWCPQSNSRNDLIQIIQHNLRPGLSLDQHDHQGKDIAELMLDFIDWLTNQEFGRRCILSVRDILSWVNFMNTVCERDEDGFMTMGELEEEEPDWDLKLDTVTAFIHAACLVYVDGIGSGTTVSAAENALVARKLSLEYLEKRLSRITELDEEMQEAIRVYNTSVSREPQWGEGFFGIDPFYIAAGSESEGRSLSDYALSAGTTAVNAQRILRALKLQRPILLEGSPGVGKTSLVAALAKASGNHLVRINLSEQTDVTDLFGTDLPVEGGKGGEFAWRDGPLLAGLKAGHWIVLDELNLASQSVLEGLNACFDHRAEIYIPELGMRFHVQQEKTKIFGCQNPFTQGGGRKGLPKSFLNRFTQVYVDALTNEDMQFIGDSIFPNIDNAIISKMVQFSNRLVQEVMVDRKWGQRGGPWEFNLRDLFRWCQLMQTDQSPGFFNPGQHVGLVYADRMRTEADKAQVLAVFRKVFGEDFEPYMGSRQFHITPLNLQLGYSVLQRSGGAPIALDPPLSITHHSLRPLEALMKCVEMGWMVILVGPTASGKSSLVHLLALLTGHRLRVMAMNSAMDTTELLGGFEQVDIIRPWQQVLESMDYVVAMVTRRGLMSLDGAVQDTEFLLSTWSTFRRWLREEGLDTTEGQLTFEALNKLEVIIVLLHKLNTKLKVFTDMSKLQMDFTLLKERLAQMQDGWTHGGFEWLDGTLVQALQAGDWLLMDNVNFCSPSVLDRLNALLEPGGSLTINERGIIDGTTPTITPHPNFRLFLTMDPTHGEISRAMRNRGVEIYIPGEHEGVCWDTLDLKMVLHTLGVTGDCVCDLLISIHSEIKKTIWDSPASSMSSLLHAASLLSGQLQRGVDLPSALLQACGEAYAFCQRTIANQQLAQEVIERQLAVLDSEDWGSGLLCAGVWPDRIPSALMCTEDSCFSSVQRDGQVLLYCLNTLSLYGKRSRPLSLVDLQRAMQSGAVLDGLQFSGGGGLDGGAENALLLLPTAVKILTERASHSDWVLRTSWISHLTKTYKHAPDTALMLLEAGCTALKAIFSSKLIGKGKCLAELLQPHSTDDYRILVDMRWNKQYLDILANTCNFEDEERYMEFMEALNAVANRIMLLMDREERAAINSTDGNSTPHNSALRLATSFSKGTVDIGHLPHPVLVHLRSFFDLWDSFILQAVQTGQPYISDHLMFEILQLLQWRDRFWLVCNSLSADPRGVCVLSLHWQWVHKNLILRLPQLLMGDSDYEGQQELHTISTAIQNSLSCSVAVASALKGIQKTLGKPLPFKLETVAECAGRLRVLCRALDVRDLRLDNSLASLWKQEVSRLRGVAMGIDSKEALLEAWGLVLQANLLLEPQTSGVLERLVSCVDQQQGHMASCGLLDSLSEDEEDEVGDSAAPGREVLLQLARRAQLWPALEELAVLNQMKVTTDLLYLSVTSGGNKKAEESLRRSFSNHLRFCMQSTPMNIRQLQPLWFLLGTERPVEELPLVWCELLSETLAVMWSGSVTSDPERWLKWNPLNPEENINSRSLLGPSDTGPGMLSRAVWSRSILGVLSSTDTSGKWDPSGSHFLSSSRVTLGEWRERTGQLQDLSAVIWDNMTMHELADFRLTDCRLQGLVLRKQLQSISELLSPGLQESYSESCDALTEGQDPIRAAHEIQIALREGLPENLLPEGFLETLVTCLTQFAHNRSQDSIQLARSGVFWVNMGLLQIQVWAPQTIFDPAVKRAYKLRYAQEELALLQEEWRGRSLSSQLLTGAELEESSTTDNFQHPRIRYLWIRMQQVKEQICELSRKQAYRPPEPQYGRLYQELQHYLCSIGQPAAVGDLLSHLLKALQAPGPKSKLGVQGLLKEEAVWQASQHRFSQRLLEEFPLYPDVVVPLRAAILQVQHGMRLLASQVSFSTTAQPGLVHLVSTMLTFPCPVASSDLACADYLCSRECLRTLKTLGKQLPATEVSRVIPDHAVLLLNALLYIQSHTLSAGQLSAEAQKLFRHVCQAIVNEWDEQEKRAREKEQMEASLYRSRSRLHGTGLTEDQQEEREFRRSFPSYHKDFADITSEPSLDQPIIIEDDDDADMKAESSETSSLLISNMSRVVQVHQRLCLSFARSLWYHSEPPTNHAKDHISALVSSYQITAPLIARFYHLMDCEVNSKLMGSQLLLSTLLQNTVSGSGGSAGLILQNDGPYDFYREPNMSQARLCLPALEQLSKAVRQRLNDWPEHPALVQIIMVIERILAFSLSSPLAKFLNGLEILLSKAQDWENNASRAVSLRNELEVVTQLIIQWRKLELNCWSSSLDNALKRHAENSTKHWLSIYQLIEKYLQEQKTNSRHDDGVENLSLSSVSSSLQAFIEGSTLGEFSVRLSMLLGFHCHILLAPKQEGHDSLCSLLWNLYKYYSQFSPSIQTKITHLRSPLEKELKDFVKISKWNDVSFWSIKHSVEKTHRTLFKFVKKFEAALKEPCAPCLVEQGSSSSMDDVDSQPEETPLLRVHRALKEALPGKGRDLQADGPEELSSENPSSLQARLPVLTRKMKKLCVQLVKKTSLPELSEDLDQFTAEIILNVQALQGLTVDRSMEQEKQKAEVKHILQQKQRALADLFKMLAQIGLSYRKGLTWSRTADSDETVCLQPVEIKVALSAVKTNDNSEQMLFAEMTNAWEGCEKYFYRSWARRNALLTALQSAVKELGLGNVERCRGFSSHLFKLLLRQRRRLAGLTEHWVHLRKLISSVQSIQSPSSESGCDVSGVPPQDSLQHWIRRAQSSALHCSVVLQQISWLLQCCPESSSVAPAEAREGEAMQGQATLSHPSPLAPHLQPQACLLRRGEQGWKVIEQKVESLIKEVKDLKMKLDGLAEESTERAICSWDHFTLCCSSLDRLAIVANQIPALEQLFIPESVVILQTQPALIRGLQSVRTEVETCLTEFTTWKTQLLSIRQSQKRHSHPFSVEFSGQLEKAINMVLCAVQTVVKRKEKEKQEDQLSESKRESDSEVVEELLKPGHLSRLLEEELSGDLSSLSLPEINGVVTELLERLRSHRDDCQPHHLQELREACRSVVRLEPMLCLYSELVRYYLAVLMGAHRTTGKLLSVLANVFTELAQKGYCLPQELMGGGDGEGATEFHDYEGGGIGEGEGVKDVSDKIENEDQVEDTFQEGKDKDEEEQDKQDIKEEDNAIEMSEDFDGKMHDGTDREPGEDEEDSDKEDEELDKKMGDLGDGQTDTLDERMWGDDDDDEDNNDDSDKEEESGPGMDQGESELVAKDDNTDAGESNKDKNQDKDLPKDEEEKEKIHEQVDEREFDENEVDPYHGKQEKKAEPEAMELPEELNLDEDGKDEEGEEANEENPFDIDDKLMEVDEKTGEDKGEPEEGGDEMTDEQQQEGQEEEHGEEDNTEEKEEAEKSEDQDPEMDERGENEEEDDNKEKNKGQEEGREEDKSIPADQGQEPKKEEDGDEDDEAPLDSAERKEHASDGQTGEENVQSDTAVELAGAASEKDQAKEEDGSGAADASQSEGHDSKLMARMSSQKQRQKNTQSFKRKPGQADNERSMGDYNERVNKRLRTVDKTEQKTQDQTQPDTQQESDLYEHIKQGDERYDAQTYDVASKEQQKPTGVKQEEEDEEDDIAMEVEEEKDLQAVEAQELKPEKLNDNKASQKGLDCGDLEAQKQAIEEEMEKLETQRSINEEEMKERSDESTIHTVPELLMETQKATLMNPEELRREMELQLEAWQRQTLGSHEEESAAAALWHQYQTLTSPLSQQLCEQLRLVLEPTQAAKLRGDFRTGKRLNMRKVIPYIASQFRKDKIWLRRTKPSKRNYQICLAVDDSSSMVDNHTKQLAFEAVSVIVNALTLLEVGQVSVCSFGETVQLLHPFHQQFNDQTGAKILRLCQFQQKKTRIAQFLETSTNMFMAAKQQIPGATNTETSQLLLIVSDGRGLFLEGKERVATAVQAARSANVFVIFVVLDNPNSRDSILDIKVPIFKGPGELPEIRSYMEEFPFPFYVILRNVNGLPETLSDALRQWFELVTATEQ", "length": 5527 }, "evidence": [ { "id": "MGI:1926159", "url": "https://alliancegenome.org/gene/MGI:1926159#orthology", "database": "AGR" }, { "id": "HGNC:18302", "url": "https://alliancegenome.org/gene/HGNC:18302#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041001-138", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041001-138#orthology", "database": "AGR" }, { "id": "FB:FBgn0033661", "url": "https://alliancegenome.org/gene/FB:FBgn0033661#orthology", "database": "AGR" }, { "id": "RGD:1306394", "url": "https://alliancegenome.org/gene/RGD:1306394#orthology", "database": "AGR" }, { "id": "SGD:S000004096", "url": "https://alliancegenome.org/gene/SGD:S000004096#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A8DYB0-1", "protein_name": "Midasin", "gene_name": "Dmel\\CG13185", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEVNVSKLRLGAQRLLELTANESEDNVFSQSLQKFIKKQKYVPQDVERLFRSLSEQLPLPAYTVPIAASFEEQLLLLLSMALRWDSASQRFHTYQLECVALSKLMNFSLDAQRFAKSYFHDKPAPFEKQQSNGSLPSKKSKNGNHAADNLDDLELIKCCFQLLKSDTPYFRELWDWSSFIATYTHNSSSPKTQLYCNYIVAMLTNMSAPQLNSLNEKISTKTRLEFDQEREQAWNTARNTLCSYTPDASDQLLNLHLHGINKSVTNIEGVLLPTFNEENLEFYASTDGCYDRIVKVDSTVVNLRSIALGVAAAKPICLSGPVGCGKTTLIEYLARKTGRICPKPNEIESREKALKKAEEEEQLLTPKKKAKTTGSKRKLEEVPLEELLDLGETTKKSGFLRIQLGDQTDSKMLLGQYRCTDVPGEFVWLPGVLTQAVMHGYWLLLEDLDAATQDTYTILSSLLERQCLSVPGFRDSVKIEPGFQLFVTVRTNKSASNSSQKSLYSLLDKYLYTINILPLSRNELCKMVSINYPKLSTVANRIVDVFLTFSSGNHTSADNLRQQESGDKADNTEQYVALPFEQVPLTSSPNSGRLVSTRDLVKLCHRSNPQFSVTSSECAYFVFQNAVDVFCSYLPQSKEKVTLITSIGAKLGIIRSRCEHFANEYKPDVEFGLEHIKIGRASLLAKSDLNNSENEDISEQDLKRQKLSQQTRRAIGKVSNKRTTFSFTRLASCILERIAVCVTHSEPVLLVGETGVGKTSSVQYLAERTEHKLVVVNMNNQSDVSDLVGGFKPVELNYVLAPLRNEFEYLLCETFNQEKNLQFLRLFATHYNSGRHAVIIRTMINICLQVAKNPELKANKLLPRWQTLREKLQKLQMQLDKSINISFAFIPGSLVNCISNGDWVLLDEINLASAETLECLSTILEPEGSVVLLERGDFTPVKRHPDFRIFACMNPNTDIGKKDLPVGIRNRFTEFFVDELTTDADLSLLVSDYLANTGIQRKSVHNIVQLYKSLRKLSELQLNDGLGNRPVYSLRTLCRSLRICARNLCGSIERNLYESFCLSFLTQLDPNSHHVVLLLIQNALLSNVKAILSKQLPQLGENYLDFEGYWIQPGNLEPQPCTHYILTESVKKNLKDLARIISIGKLPILLQGPTSAGKTSLIDYVARRSGNRCLRINNHEHTDLQEYIGTYAADLDGKLTFREGVLVQAMRHGFWIILDELNLASTDILEALNRVLDDNRELYIAETQTLVKAHPNFMLFATQNPPGLYGGRKTLSRAFKNRFIELHFADIPREELETILEKRCFIPPTYARKMVQCMTQLQQHRKNTSKQVFTLRDLFRWGNRYTHADKSLHDDNRYDWNQHLVEEGYLVLSSKVRSQEEHELIEKTLFANFRKKLDLQTLFDIQTDRESSSMVSRKILDAIRNFKLRDDIVWTRNMTRMAVVTAKALEFDEPVLLVGPTGCGKTTVCQLLASIADVQLRILNCHMHTEGADFLGGLRPCRGKESTQLFEWADGPLIYAMQEGSYFMADEISLAEDSVLERLNCILEPERTVLLAEKGGISELDASPDFVVQAKSGFQFLATMNPGGDFGKKELSPALRNRFTEVWCLPSDNKEDLIEIAYNCMRRQKEHENQAINTHKVAEYLVDVVLHIRDTNDKFKFSVRDILAWANYMVSNAKLSFAEQAIFGLETIFLDALEMLPHESQEQVELLKSNIVKQAIKQASLILQEKFTLEELSEKRGTEVELNECRFGIRPFFIDVNQERLTSAKEDFLFDAPTTKQNLFRLLSALSLQKPVLLEGPPGVGKTSIVESIGSAIGYQIVRINLCEHTDLADLFGTDLPAEDNLLESNTAATERQIRSFVWRDGPLLAALKAKNTWILLDELNLAPQSVLEGLNAVLDHRGEVYIPELNKSFHLAGSTRIFACQNPLKQGGGRKGLPQSFLNRFTKVYLRKLSTEDLLHVVTEKYGKYFDQLNAYFLELLDQKAEGNLFEIYSGKESSCKSDSFDLGARLVRFSEQLDRGVASMEFGYKGGPYEFNLRDILRWCDLLHNPQTGYILGASPSSFQAAFKDFLLTLYERMQLVYYQRMRCDQDKSYIRNVFSTVFLCDAEYLNQVSNDVALYWTADKVYLNDVVLSRKQADVLDLVNRQEQSPLLLDSQRQQLKQIIETVHMEKPLLLCGSTDSGKTKLIDALCVLSNRLCNTDIIDDSVTGSFQQIDLNRHLEIIYKKVETLVFSCVQRAFVLHTQSEFVEQLWNNWSMYNKLAKVTTEAQQHSVLDELKLFSERLGSLGKIIEVLEATPQNCQVRALQQLAEIKSQLLLLQTYIKTADSLNTGGSFEWVDSQIVTSLKCGQYILLEHVNLCSSAVLDRLNPVFEPNGSLLIAEKGISAQDSAEVVYKSTNFRAFLTVDPKNGELSRAMRNRCVELSLSRDTYSVDDLRAFVHEQGVREMEAIDCILRVHKGLSQLTEFNNYSISHLTQFAFLSAAYRRIGYELKRAIYVAAMEVYVYSANTDLMGYGLSYYQNKLREVVLAQTEVFEEVAVIQEDFLSDVILNSGNLNSLTLIKRQAVALKVLLDGYTEGKIPQKLLASLFHEMEKLKLDQRNPQKLIRHFLYMLYESSAIGDLELRHLYLQPWLSKDTAFQELSQNLYNCLQKRSNTDTGTLANLPWNRKLIPRLRDYSTAESNSELNPLNLSALLLARLVVDIIPVSSVTTVQQMNALQYSQALCKKQVTEKYANHLLANFSSFLEVLHTSLLEDLETADLDLPQYAHLVTRFHWFNRILATAQQKLLYNNELHVPLMHKLVLHFQWLEKHLLVPLIELTAKSGCARMLTIQDRTLKIKKYIEETRRPLNVTCKIYSKQFTQFQPYYQDQQIQRHIELDDLEKLLSVVPSYGNLELSSWLKRWLLLQTDDANKWRSFLRKHTNGFQPKAFEISGSLRNETLQSHLQKLQTTLKEAQENSAEIEMDLELDLNSIKTLLEAETEESESYIHPDGIPTNTPKLLIAALRELFMERLLTGTLRDDFDEQVNPLYADQLLTLNSNLWHCLKTLESANRTEITNAWIELKNEVNELQNYDEFAVLLEKIGGGYKGLRSYQRQYRNSVQCYQLENLSTRLDCVQGPSEEGSTDISSQFCYRGPALSGVILSLICQPNGQLRSVPLSELLEWRSALQQTRHLIWENSQLLTSRYSGEVNNLLQAKENARQLLKELEYVRKLSEKEQKANQGFENCAKELEKMIEKLEKEENNNASMTKDFEVSLTNALVGAIELCLLTNTPLIDPVEKNRLKNEYIAEDIDCLSTLTTAYDFMKIAMKYRHFGEEIYSELELRLRTALQRQQQLSQKLALRSEKCLYASLVQDITHFLHSNGDCESLYKLFQLIHSEWENFQGLHVATSAQLKSSIEVLGKLDLWLANAQRFVHHTLSRYSAYYQDFVEPIKCSVNQLRFGLESLKVIFTRVQQAGSVSQAEQMQQTIGDIVQFPSQHPLVIRNSRLYGLLAELPHSEYEYFRLLKAKLSELSNYIALGRVIDETTFAAYDDALSICNQTWQQEEHRRCQLKAEAESLYVTKTKGGVDSEELIEMQEIEHNFPTNLDEDFAEFVSQPTLEQVLKLDKKASAKDKQSQIVVEEDYAFLARNFIDVMTRHTQVYYKEQPKSSKELELHLLAPYQARFQVFANLHGHYKTALGSSLEERACNGLAFGLALQQKQLRDIELEEGVSSSPYDFYKDSNISEIQSCLDVMERIEKRVLEQLEQYPEHAGLADIKLVISRIRRLPAHAPVVRFNTGFQLLRQKLALWNEVAHRNNNLVSEEIEVAEFVQRWTRLELQHWRNCLGQTAAQVELQAYRYWFFIYNLLQQFIHQKQLDHSYTDIKLAEQRFAQDHLLDAQDLGESQRLELAQVVRILRQFVEASCYGDFHIRLQLLQGFELYLHNVERAGKINGLPPLIAALHNLQLYFSQFAGEIADSAKLRRSPIEKKLKEFVKIQSYSKDLSYFSMRNSVASVHRNLNKFLKEYRLSIQEKISEVFQPKDSTAKDYTFGTDKGKGLRNYNKIKYLHTERQQFVASEKLLEKFAIQEEFLSDNTLLQRLDKHFRTARHVVKETLGQVPYGELITELDDLLASQLERCEHLRSLNVDRSKERPQQKQEAKQILQQKRKALTDLFKMLHRLGANYKTGLLELSLRNEFEDFQLPPYSIRSMLPRLHPTAQQLDEHLDLYYMKSVFKLKLLQNIMLTPLSELGPPNIERIKGFAVDLFLLVQQQREHLSGSTKELHELRNSLDSLRKLAEIIPQADINPSTLNFVKSADIAMEIKQHLRQIHYVLKQWKLLLSCAPSSFIEESENRLLVRKISLAQSELHSLCIQILNSSQELLNELNNANLEYLSSEKCVTYQKSYAEIQENIKKTLELLRTGQNDYLPLAQPIVELLDSVQLKNHTEIAPEAIDLANADTELANIAHSVLMSMQKIYKHHVKTDEVNQNGEAKEQDEESKEALQEQHLKKCLTGELTSDWQQLSLPRVLGKLSNVLLVLKHSHFEGKDKLLCVRRAIGLLPVLEQYQLLADYLLLQQLATHKVSAKMLSIVLTVFVEIGSKGFCVPPDLMQDEEGQSKQESKNGEGFGLEDGTGENDASDKIESEDQLDDAKRPEDRKDEGDKQEPDCKEEKGIEMSDDFDAKMQDVEKPEEDDSGESEEEEDLNKEMGETEEGAEKLDDQIWGDDEEEKPEEEQEPDMNEEDQGKGSKDEKDAHNDLDTKNDAAKEDGKDEHEKDGLDATNEPSGEDKRKEQAKDIDDMKDPEMDEEQTNAMHNELEEPPEPEEMDLGDMNNVDEGHDDQDEQPTDENPFDIDAMKENMQPAEEPEADGDDEHDANEEGDPQSDGSDSEEDEAGTEAKPAEEDHGEGEEATPEDEKDEAETQKRGELEDEDDSKPEDSPEDSKEEKEEKREEKPEEHSQSKDKASKEENVQSMPETDQSSSADQVQQPQDPDIKQDQKLDEQETGEEKDGVGQAENDADDGGHQGVAETQETVSQEDRKNERQTQEKRKQGRTNEERSLGEAEQNKLKQLKTIDQLKDSKESDDAEQEKPEPMDQTEAEEYQHVKEPKNSDKTTLDNATEEQSKKIQHQEDEPPNEEEIEAENVDELMEAEEPAVDPEDDAELEQLGAEKTEQKSDKPSKTEKSKEQLETPEGMEIEGEVVLTMTVPRSSETTAHSNSEILLDKSSHAEDLSSAEQIELRQQYQKQLTTFRVAQPEHEDYETWQGISNRMTQNARELCEQLRLILEPTKCTRLKGDYRTGRRINMKKIIPYIASQFRKDKIWLRRTKPAQRDYKITIAIDDSKSMHHNNSKTLTLEAISLVSQALTLLESGRLSIVSFGEAPQIILNHTEQFDGPRLVNALNFAQDKTKIAGLLNFIRTANAEESGTGGDNGLFENLLLILSDGRNIFSEGAQNVKNAIKLARLQRIFLVYIIIDNPDNKNSILDIQHVAVNADGSVNINSYLDSFPFPYYVIVRDLNQLPLVLSEAMRQWFELVNSE", "length": 5526 }, "evidence": [ { "id": "MGI:1926159", "url": "https://alliancegenome.org/gene/MGI:1926159#orthology", "database": "AGR" }, { "id": "HGNC:18302", "url": "https://alliancegenome.org/gene/HGNC:18302#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041001-138", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041001-138#orthology", "database": "AGR" }, { "id": "FB:FBgn0033661", "url": "https://alliancegenome.org/gene/FB:FBgn0033661#orthology", "database": "AGR" }, { "id": "RGD:1306394", "url": "https://alliancegenome.org/gene/RGD:1306394#orthology", "database": "AGR" }, { "id": "SGD:S000004096", "url": "https://alliancegenome.org/gene/SGD:S000004096#orthology", "database": "AGR" }, { "id": "Q9NU22", "url": "https://omabrowser.org/oma/group/Q9NU22/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "J3QMC5-1", "protein_name": "Midasin", "gene_name": "Mdn1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEHLSVELVSGPLRLIAAKNEKSSGELNRFLAKSVWTPQDRQCILDSLAQLLLDKDYTLLLGRQLRPILLDLLERNAKAIKTGGQVNHDLHERLSVSMSKLIGSHPDVLPFALRYFKDTYPVFQRLFLESSDANPVRYGRRRMKLRDLMEAANIFLQHRQTVFRELWDWSVCVPLLRSHDALVRWHTANCLALVTCMNEEHKLSFLRKIFSSDELVHFRLRLLEEAQLQDLEKALVLANPEVSLWHKGEEPQYIQGHLVSADLSSSVAAVCGVVLPKLSSSPGEQASDRSSSLEQELALKSFVLVESVCKNLQLLAVSVASQNAVLLEGPIGSGKTSLVEHLAAVTGRTKPPQLLKVQLGDQTDSKMLLGMYRCTDVPGEFVWQPGTLTQAATKGYWILLEDIDYAPLDVVSVLIPLLEHGELLIPGHGDCLKVAPTFQLFATRRLLSCGGSWYRPMNSHATMLDKYWTKIHLHNLNKKDLNEVLQSKYPSLLAATDHLLDIYIELTGEKHCCPSVAYDKAPQEVSEAERENRRVVLEGRELSLRDLLNWCNRVAHGFDPTSSTALLHIFQEAMDCFTAMLSEQTKKLRMAEVIGSRLNISKKKAEFYCKLYKPEIVINELDVQVGRVRLLRKQSEVVRIQKEKCTFAATRPSSVLLEQLAVCVSQGEPVLLVGETGTGKTSAVQYLAYATGQHLRVVNMNQQSDTADLLGGFKPVDHKLIWLPLRETFEELFVQTFSKKQNFTFLGHIQTCYRQKRWHDLLKLMLHVQKSASTKGGEQSQPGLLKEKWEAFGLRLNHAQQQMKMTENALLFAFVEGTLAQAIKKGEWILLDEINLAAPETLECLSGLLEGSSGSLVLLDRGDTEPLVRHPDFRLFACMNPATDVGKRNLPPGIRNRFTELYVEELESKEDLQILIVDYLKGLNVSKNTVQGIVNFYTALRKESGTKLVDGTGHRPHYSLRTLCRALRFAASNPCGSIQRSLYEGFCLGFLTQLDRASHPVVQKLICQHIISGNVKSLLKQPIPEPKGGRLIQVEGYWISVGDKEPKIDETYVLTPSVKLNLRDIARVVSAGTYPVLIQGETSVGKTSLIRWLAAASGNHCVRINNHEHTDIQEYIGCYTSDTSGKLVFNEGVLIDAMRKGYWIVLDELNLAPTDVLEALNRLLDDNRELLITETQEVVRAHPRFMLFATQNPPGLYGGRKVLSRAFRNRFVELHFDELPSSELETILHKRCSLPPSYCSKLVKVMLDLQSYRRRSSVFAGKQGFIALRDLFRWAERYRLAEQTQEDYDWLQHLANDGFMLLAGRVRKQEEADVIQEVLEKHFKKKLCPQSLFSKENVLKLLGKSSTQTTVLESKFSHVVWTESMRRLAVLVGRALEFGEPVLLVGDTGCGKTTVCQMFSALANQKLYSVNCHLNMETSDFLGGLRPVRQKPNDKDELDTRLFEWHDGPLVLAMKEDSFFLLDEISLADDSVLERLNSVLEVEKCLVLAEKGSPESKDNEVELLTAGKHFRILATMNPGGDFGKKELSPALRNRFTEIWCPQSTKREDLIQIINHNLRPGLSLAGVGHKGAGVAEVMLAFITWLTRQEFGRKCVVSIRDILSWVNFMNSMAEDAAVKRPEAISTVTSFVHAACLVYIDGIGSGVTSSGFGTALLAREECLKFLIKKLSKVVRLTQRQKDELKIYDRLRHKEFTSIDDFWGVHPFFIPRGPVLDGHNTGDYALTAGTTAMNAQRLLRAAKLNKPILLEGSPGVGKTSLVAALAKASGNTLVRINLSEQTDITDLFGADLPVEGGRGGEFAWCDGPLLAALKAGHWVVLDELNLASQSILEGLNACFDHRGEIYVPELGMSFQVQHEKTRIFGCQNPFRQGGGRKGLPKSFLNRFTQVFVDPLTVVDMEFIASTLFPTIDKDIVKKMVAFNNHIDHEVTVEKKWGQKGGPWEFNLRDLFRWCQLILVDQSPGCYDPGQHVFLVYGERMRTREDKEKVVAVFKDVFASNSMPYIGTRQFHITPYDIQIGYSVLSRSSYVPHPSRRPLSLLHQSFQSLEPIMKCVQMNWMVILVGPASVGKTSLVQLLAHLTGHTLKIMAMNSAMDTTELLGGFEQVDIIRPWRLLLEKVERTVRVLLRDSLLINSVDTEVVLQAWSHFLLTYKPKCLGEDGKGVTIEIVNKLEAVLLLMQRLNNKINSYSKADFAKLVEDFRSFGVKLLQSASGRSHGSFEWVDSMLVQALKSGDWLLMDNVNFCNPSVLDRLNALLEPGGVLTINERGMVDGSTCTVTPNPNFRLFLSMDPIHGEISRAMRNRGLEIYISGEEDGSIQDNLDLKVLLHSLGLVGDSVCNILLALHTEIQSLVRGSPASSVSTLSHTAILIVQYLQRGLSLHKAFFEACWEVYVCSQHSAANQKLVQDLLESHTASLQARETWGHSILATGLWPDSVPSALFATEDSRLSVVRSEGQILAYCLNRMSLKTSSWTRSQPLTLQDLENIMQTCSPDDLTFNAVEVDTCWVDEPEVLATAVKLLIERATNQDWMLRVKWLCHLAKNIPQGLESVRVHLEASATALRKFYSTSLSAGVSNVLKILQTNITDDFVIPLDPRWNMQALDIIRNSLDFDPQSDQAKQLFALLESVANKTFIYLDREKRIFTEANLVSVGSKKLRSSVLRMSFEFHKDPENYHSPPHEIVANLAAFFELIDGLILLWVQSPQGVVPDAHINKILGSVQWRDRFWTVADTVTVDASGLALLALHWHWVSKHLIYQIPQLLVNQENKYYKELQTVSEHIHSCLGSPADSFAGVKKLQAFLGRPFPFKDKLVVDCFLQLQALNRALAIGEQLPVFGECGWQEDINRLQVVASEWNLKKSLLQAWGLILRANILEDVNLDELKNLVSTQCSELKSRGLSRGFLEKAHDASSPSQPDLSSLVHLTRRVQLWPAAEYLAMLWQYRVTADFIAQACLRRSSKHDQMDEEISHHIAFCLKHTPIAPQKLWNLWSLLHIEMLSAQEVSCLWSELFTSTFGSSWSSPVTTAPECWLAWSPLPNIQQQEVPRSRWDSTLKGPGSLCRAVFSKCCFGVLTNSSRASYWDVSGLPLLSSSHVTLGEWVERAQQLQDISSLLWTNMAVPSVAEFRRTDSRLQGLVLCRYLLGLTELLPAHQRQEYMQNCEHLLLGNTQAFHHVDQTMGNIGGQEALPKELLCLLLTSLHYFIGEGEGKQNLPEAARRGRLWVSLGLLQIQTWLPRARFDPAVKKAYKLRYAQDELRQLQCELKTRNLLSHLQTGRDLEDDIITSHSHPHIKLLPQRISQLESLVHSLSKKQAFRPHLPSYETLVQEIHHYVTSIAKVTAVQDLLMRLLQALHTDGPKSAQVLQNLLKEEASWQQSHHQFRKRLVEEYALYPDTVAPLLASILQLQHGMRLVASEVHASLHSGVLCAENLGALAMAVLAFPSVGPSFPTYHAHADALCSVNAAEALRSLGKLMVKRAARKEEAKSQQAYPTREQLLMNALLYLRSHVLCKGELDQRALLLFRHLCQEIINEWDEQERIAQEKAEQESSLYRYRSRSGRTALSEEEEEELELRKLFPLHEKDFADILMEPTLEEKKKVSDGREEEAAPDPTLLCQSSMQAVMLIHQQLCLSFARSLWYQQAVPPHEAKHYLSLFLSCYQTGASLVTHFYPLMGVELNDQLLGSQLLACTLSSNTLCGEATSDLMMRPDGPYDFYQHPNVAEARQCQPVLQGFSEAVSQLLQDWPEHPVLQQLLVVMDRIRGFPLSSPISKFLNGLEILLAKAQDWEENASRVLSLRKHLDLVSQMIIRWRKLELNCWSMSLDNTMIRHTEKSTKHWFSIYQMLEKHMQERTEEQEDDKQMTLMLLVSTLQAFIEGSSLGEFHVRLQMLLVFHCHVLLMPQVEGKDSLCSVLWNLYHFYKQFLDPVKAKIMELRSPIEKELKEFVKISKWNDVSFWSIKQSVEKTHRTLFKFMKKFEAVLSEPCQSCLVESDKEEQPDCLPKPTEEATMETSPIQGLNNALRETLLAQPVEWKPSGTEQCQDASPLSVEGELLRRLPRLSKRMRKMCLVFMKESPLPHLVESLDQFTGGVISSVSELQSLKVDPSAEKEKQHSEAKHILLQKHRALSDLFKHLANIGLSYRKGLAWARSKSPQELLHLHPLDLRSALSIVSSTREADSRLLTEISSLWDGCQKYFYRSLARHTRLTAALATPVKEVSMGTIERCKGFSAHLMKLLIRQRHSLTTLTEQWIILRNLLSCVQEIHSRLTGPPVYPVAFPPQDSVQQWTERLQHLAMQSQILLEQFSWLFQCCPSAEPTVGHRDAQVQEHPSASHLENIDFKETIAGVMPDLLSSDLSYPSPVPTSQLPSACRMRRQDQLWQQSTAGLTEMLKTIKTMKAGVDKIRQQSCETLFHTWEDFEVCSSGLNCLSQVSAHLQGLASLFILPGIEVEQTDSRMALVESLDYLRGEVSKAIDDFTAWKARLFVAHKQEGNQMVEESFVEDFSEQVETAIRAILCTIQNLAERNNKKAEDSAVDKRLQEEDEASFKSLQPGHLTKLLEDDFWASVSTLHVQKIISSVSELLERLKSCSEDGNTTKHKVFSQSCGLLVRLIPILCGFSDLVLFFLTVSLATHRSTAKLLSVLAQTFTELSQKGFCLPKELMEDSAGEGATQFHDYEGGGIGDGEGMKDVSDRIENEEQVEDTFQKGQEKDEEDLDSKPDTKGEDNAIEMSEDFDGKMHDGELEQEEDDEKSDSEDGDLDKQMGNLNGEEADKLDERLWGDDEEEDEDGDGRAEETGPGVDEEDSELVAKDDSLDAGNLNKNKKHQDEKEDSEPEDVEQGQEKINEQIDEREYDENEVDPYHGNQEKLPEPEALDLPDDLKLDSEDKSGGEDTDNEEAEEENPLEIKEKTVDMEETDHEIEEPGAGQDEGESPHEPEEGPSEDKENMDMDTGADDQDRDTSSHAEEHSLEEEAEEEEEKGEKEEDKATTDGGGESGVNPVDQGLQPQEEEEGEQSDAEEQVPEATERKEHATCGQTGVDNVQSAQAVELAGAAPEKEQGKEEHGSGAADANQAEGHESNLIARLSSQQHTNKNTQSFKRRPGQADNERSVGDYNERVRKRLRTVGTDRETEQEPTQAQVEDADAFEHVKQGSDAYDAQTYDVASSEQQQTAKASGQDQEEEEIEDILMDTEEELMRAEDTEQLKPEAVQSETAATSGSSEMEVDMQTLKTKEDQDPRTTTPHQETENERPERSRDSTIHTLRQFLVDSVFQPILKDISELRQEMERQLETWQAHDYGNAEEEKAAAEMWQNYLVLTASLSQQLCEQLRLLLEPTQAAKLRGDYRTGKRLNMRKIIPYIASQFRKDRIWLRRTKPSKRQYQICLAIDDSSSMVDNHTKQLAFESLAVIGNALTLLEVGQIAVCSFGESVKLLHPFHEQFNDSSGTHILRLCTFQQRKTKIAQFLETVAKMFAAAQKLSQNVSPETAQLLLIVSDGRGLFLEGKDRVLAAVQAAQNANIFVIFVVLDNPNSRDSILDIKVPIFKGPGEMPEIRSYMEEFPFPFYIILRDVNALPETLSDALRQWFELVTASDHS", "length": 5582 }, "evidence": [ { "id": "MGI:1926159", "url": "https://alliancegenome.org/gene/MGI:1926159#orthology", "database": "AGR" }, { "id": "HGNC:18302", "url": "https://alliancegenome.org/gene/HGNC:18302#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041001-138", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041001-138#orthology", "database": "AGR" }, { "id": "FB:FBgn0033661", "url": "https://alliancegenome.org/gene/FB:FBgn0033661#orthology", "database": "AGR" }, { "id": "RGD:1306394", "url": "https://alliancegenome.org/gene/RGD:1306394#orthology", "database": "AGR" }, { "id": "SGD:S000004096", "url": "https://alliancegenome.org/gene/SGD:S000004096#orthology", "database": "AGR" }, { "id": "Q9NU22", "url": "https://omabrowser.org/oma/group/Q9NU22/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q12019-1", "protein_name": "Midasin", "gene_name": "MDN1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSQDRILLDLDVVNQRLILFNSAFPSDAIEAPFHFSNKESTSENLDNLAGTILHSRSITGHVFLYKHIFLEIVARWIKDSKKKDYVLVIEKLASIITIFPVAMPLIEDYLDKENDHFITILQNPSTQKDSDMFKILLAYYRLLYHNKEVFARFIQPDILYQLVDLLTKEQENQVVIFLALKVLSLYLDMGEKTLNDMLDTYIKSRDSLLGHFEGDSGIDYSFLELNEAKRCANFSKLPSVPECFTIEKKSSYFIIEPQDLSTKVASICGVIVPKVHTIHDKVFYPLTFVPTHKTVSSLRQLGRKIQNSTPIMLIGKAGSGKTFLINELSKYMGCHDSIVKIHLGEQTDAKLLIGTYTSGDKPGTFEWRAGVLATAVKEGRWVLIEDIDKAPTDVLSILLSLLEKRELTIPSRGETVKAANGFQLISTVRINEDHQKDSSNKIYNLNMIGMRIWNVIELEEPSEEDLTHILAQKFPILTNLIPKLIDSYKNVKSIYMNTKFISLNKGAHTRVVSVRDLIKLCERLDILFKNNGINKPDQLIQSSVYDSIFSEAADCFAGAIGEFKALEPIIQAIGESLDIASSRISLFLTQHVPTLENLDDSIKIGRAVLLKEKLNIQKKSMNSTLFAFTNHSLRLMEQISVCIQMTEPVLLVGETGTGKTTVVQQLAKMLAKKLTVINVSQQTETGDLLGGYKPVNSKTVAVPIQENFETLFNATFSLKKNEKFHKMLHRCFNKNQWKNVVKLWNEAYKMAQSILKITNTENENENAKKKKRRLNTHEKKLLLDKWADFNDSVKKFEAQSSSIENSFVFNFVEGSLVKTIRAGEWLLLDEVNLATADTLESISDLLTEPDSRSILLSEKGDAEPIKAHPDFRIFACMNPATDVGKRDLPMGIRSRFTEIYVHSPERDITDLLSIIDKYIGKYSVSDEWVGNDIAELYLEAKKLSDNNTIVDGSNQKPHFSIRTLTRTLLYVTDIIHIYGLRRSLYDGFCMSFLTLLDQKSEAILKPVIEKFTLGRLKNVKSIMSQTPPSPGPDYVQFKHYWMKKGPNTIQEQAHYIITPFVEKNMMNLVRATSGKRFPVLIQGPTSSGKTSMIKYLADITGHKFVRINNHEHTDLQEYLGTYVTDDTGKLSFKEGVLVEALRKGYWIVLDELNLAPTDVLEALNRLLDDNRELFIPETQEVVHPHPDFLLFATQNPPGIYGGRKILSRAFRNRFLELHFDDIPQDELEIILRERCQIAPSYAKKIVEVYRQLSIERSASRLFEQKNSFATLRDLFRWALRDAVGYEQLAASGYMLLAERCRTPQEKVTVKKTLEKVMKVKLDMDQYYASLEDKSLEAIGSVTWTKGMRRLSVLVSSCLKNKEPVLLVGETGCGKTTICQLLAQFMGRELITLNAHQNTETGDILGAQRPVRNRSEIQYKLIKSLKTALNIANDQDVDLKELLQLYSKSDNKNIAEDVQLEIQKLRDSLNVLFEWSDGPLIQAMRTGNFFLLDEISLADDSVLERLNSVLEPERSLLLAEQGSSDSLVTASENFQFFATMNPGGDYGKKELSPALRNRFTEIWVPSMEDFNDVNMIVSSRLLEDLKDLANPIVKFSEWFGKKLGGGNATSGVISLRDILAWVEFINKVFPKIQNKSTALIQGASMVFIDALGTNNTAYLAENENDLKSLRTECIIQLLKLCGDDLELQQIETNEIIVTQDELQVGMFKIPRFPDAQSSSFNLTAPTTASNLVRVVRAMQVHKPILLEGSPGVGKTSLITALANITGNKLTRINLSEQTDLVDLFGADAPGERSGEFLWHDAPFLRAMKKGEWVLLDEMNLASQSVLEGLNACLDHRGEAYIPELDISFSCHPNFLVFAAQNPQYQGGGRKGLPKSFVNRFSVVFIDMLTSDDLLLIAKHLYPSIEPDIIAKMIKLMSTLEDQVCKRKLWGNSGSPWEFNLRDTLRWLKLLNQYSICEDVDVFDFVDIIVKQRFRTISDKNKAQLLIEDIFGKFSTKENFFKLTEDYVQINNEVALRNPHYRYPITQNLFPLECNVAVYESVLKAINNNWPLVLVGPSNSGKTETIRFLASILGPRVDVFSMNSDIDSMDILGGYEQVDLTRQISYITEELTNIVREIISMNMKLSPNATAIMEGLNLLKYLLNNIVTPEKFQDFRNRFNRFFSHLEGHPLLKTMSMNIEKMTEIITKEASVKFEWFDGMLVKAVEKGHWLILDNANLCSPSVLDRLNSLLEIDGSLLINECSQEDGQPRVLKPHPNFRLFLTMDPKYGELSRAMRNRGVEIYIDELHSRSTAFDRLTLGFELGENIDFVSIDDGIKKIKLNEPDMSIPLKHYVPSYLSRPCIFAQVHDILLLSDEEPIEESLAAVIPISHLGEVGKWANNVLNCTEYSEKKIAERLYVFITFLTDMGVLEKINNLYKPANLKFQKALGLHDKQLTEETVSLTLNEYVLPTVSKYSDKIKSPESLYLLSSLRLLLNSLNALKLINEKSTHGKIDELTYIELSAAAFNGRHLKNIPRIPIFCILYNILTVMSENLKTESLFCGSNQYQYYWDLLVIVIAALETAVTKDEARLRVYKELIDSWIASVKSKSDIEITPFLNINLEFTDVLQLSRGHSITLLWDIFRKNYPTTSNSWLAFEKLINLSEKFDKVRLLQFSESYNSIKDLMDVFRLLNDDVLNNKLSEFNLLLSKLEDGINELELISNKFLNKRKHYFADEFDNLIRYTFSVDTAELIKELAPASSLATQKLTKLITNKYNYPPIFDVLWTEKNAKLTSFTSTIFSSQFLEDVVRKSNNLKSFSGNQIKQSISDAELLLSSTIKCSPNLLKSQMEYYKNMLLSWLRKVIDIHVGGDCLKLTLKELCSLIEEKTASETRVTFAEYIFPALDLAESSKSLEELGEAWITFGTGLLLLFVPDSPYDPAIHDYVLYDLFLKTKTFSQNLMKSWRNVRKVISGDEEIFTEKLINTISDDDAPQSPRVYRTGMSIDSLFDEWMAFLSSTMSSRQIKELVSSYKCNSDQSDRRLEMLQQNSAHFLNRLESGYSKFADLNDILAGYIYSINFGFDLLKLQKSKDRASFQISPLWSMDPINISCAENVLSAYHELSRFFKKGDMEDTSIEKVLMYFLTLFKFHKRDTNLLEIFEAALYTLYSRWSVRRFRQEQEENEKSNMFKFNDNSDDYEADFRKLFPDYEDTALVTNEKDISSPENLDDIYFKLADTYISVFDKDHDANFSSELKSGAIITTILSEDLKNTRIEELKSGSLSAVINTLDAETQSFKNTEVFGNIDFYHDFSIPEFQKAGDIIETVLKSVLKLLKQWPEHATLKELYRVSQEFLNYPIKTPLARQLQKIEQIYTYLAEWEKYASSEVSLNNTVKLITDLIVSWRKLELRTWKGLFNSEDAKTRKSIGKWWFYLYESIVISNFVSEKKETAPNATLLVSSLNLFFSKSTLGEFNARLDLVKAFYKHIQLIGLRSSKIAGLLHNTIKFYYQFKPLIDERITNGKKSLEKEIDDIILLASWKDVNVDALKQSSRKSHNNLYKIVRKYRDLLNGDAKTIIEAGLLYSNENKLKLPTLKQHFYEDPNLEASKNLVKEISTWSMRAAPLRNIDTVASNMDSYLEKISSQEFPNFADLASDFYAEAERLRKETPNVYTKENKKRLAYLKTQKSKLLGDALKELRRIGLKVNFREDIQKVQSSTTTILANIAPFNNEYLNSSDAFFFKILDLLPKLRSAASNPSDDIPVAAIERGMALAQSLMFSLITVRHPLSEFTNDYCKINGMMLDLEHFTCLKGDIVHSSLKANVDNVRLFEKWLPSLLDYAAQTLSVISKYSATSEQQKILLDAKSTLSSFFVHFNSSRIFDSSFIESYSRFELFINELLKKLENAKETGNAFVFDIIIEWIKANKGGPIKKEQKRGPSVEDVEQAFRRTFTSIILSFQKVIGDGIESISETDDNWLSASFKKVMVNVKLLRSSVVSKNIETALSLLKDFDFTTTESIYVKSVISFTLPVITRYYNAMTVVLERSRIYYTNTSRGMYILSTILHSLAKNGFCSPQPPSEEVDDKNLQEGTGLGDGEGAQNNNKDVEQDEDLTEDAQNENKEQQDKDERDDENEDDAVEMEGDMAGELEDLSNGEENDDEDTDSEEEELDEEIDDLNEDDPNAIDDKMWDDKASDNSKEKDTDQNLDGKNQEEDVQAAENDEQQRDNKEGGDEDPNAPEDGDEEIENDENAEEENDVGEQEDEVKDEEGEDLEANVPEIETLDLPEDMNLDSEHEESDEDVDMSDGMPDDLNKEEVGNEDEEVKQESGIESDNENDEPGPEEDAGETETALDEEEGAEEDVDMTNDEGKEDEENGPEEQAMSDEEELKQDAAMEENKEKGGEQNTEGLDGVEEKADTEDIDQEAAVQQDSGSKGAGADATDTQEQDDVGGSGTTQNTYEEDQEDVTKNNEESREEATAALKQLGDSMKEYHRRRQDIKEAQTNGEEDENLEKNNERPDEFEHVEGANTETDTQALGSATQDQLQTIDEDMAIDDDREEQEVDQKELVEDADDEKMDIDEEEMLSDIDAHDANNDVDSKKSGFIGKRKSEEDFENELSNEHFSADQEDDSEIQSLIENIEDNPPDASASLTPERSLEESRELWHKSEISTADLVSRLGEQLRLILEPTLATKLKGDYKTGKRLNMKRIIPYIASQFRKDKIWLRRTKPSKRQYQIMIALDDSKSMSESKCVKLAFDSLCLVSKTLTQLEAGGLSIVKFGENIKEVHSFDQQFSNESGARAFQWFGFQETKTDVKKLVAESTKIFERARAMVHNDQWQLEIVISDGICEDHETIQKLVRRARENKIMLVFVIIDGITSNESILDMSQVNYIPDQYGNPQLKITKYLDTFPFEFYVVVHDISELPEMLSLILRQYFTDLASS", "length": 4910 }, "evidence": [ { "id": "MGI:1926159", "url": "https://alliancegenome.org/gene/MGI:1926159#orthology", "database": "AGR" }, { "id": "HGNC:18302", "url": "https://alliancegenome.org/gene/HGNC:18302#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041001-138", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041001-138#orthology", "database": "AGR" }, { "id": "FB:FBgn0033661", "url": "https://alliancegenome.org/gene/FB:FBgn0033661#orthology", "database": "AGR" }, { "id": "RGD:1306394", "url": "https://alliancegenome.org/gene/RGD:1306394#orthology", "database": "AGR" }, { "id": "SGD:S000004096", "url": "https://alliancegenome.org/gene/SGD:S000004096#orthology", "database": "AGR" }, { "id": "Q9NU22", "url": "https://omabrowser.org/oma/group/Q9NU22/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q869L3-1", "protein_name": "Midasin", "gene_name": "mdn1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKFKFNIFKAIKALELELTKIKNESSSSTIIQDFKSFEQIFKKKENEFTSQDKLFIVEEISNLLMSKPEYPSLISNIFSPLLVDLVSRYIQNGKKEERWLGLVQSCFRLLSFNKSLFSSLWDWTPLFSLLEIKSQRITWYVIKSMSMVLNVPDHQITQIKPLFKQYHNQIIQIESELLNLESSKLFLNNNNNNNNKKENINNNQEEEKEDEELINKYPNIFIQKQDLHKSIVDVCGILLFKKFEQIGHGSSVKSKKGGEQQQEGEGEDEQVQKLVYTNTVSQNLNSLAIAVGLGKPILIEGVTGSGKTTMIEELSRITGNDNIIRIHLGDQTDSKVLLGTYITSDTPGEFKWQAGALTQAVQEGRWILIEDIDLAPIEVLSVLIPLLENRTLFIPGRGEVIEASNGFQLFATQTLFGSHSRDQNANILSHLWTRVVIEALSPTEMKQVLLTLFPQLTVMISKFIETFNLLLRVISNQSISISPTDEVAGIANIANTANVNNINNNNNTDNNNNNNSNEKFIIPSSRFISSRDLIKWIRRCNQRLHLTNVSQQIITSTMQEIVFVEALDCFCSMISKKNLRKQLTQVIGRVWELTGDRINYYVELYKPSIIITQESVSTGRAKLKSLEKSDSIQISNGKKHTRFTTEQSQQDSGVTKHGNVFAHTMNSLRLMEKISISIQFNEPILLVGETGTGKTSVVQYIADQLNQKLVVLNLNQQSDSSDLIGGFKPVEMRLLCLPLKNRFDSMFKKTFSESNNTDFLEKIDKAFISKNWKQFIALLNKAIKLVENKVLKDDQTTTNNTKENNNNNNNNNNNNNNNNNNKKRTIRSEVKEKWIKLSNDIKKLTIQFEKSKNNFAFSFVEGSLVNCIRKGYWVLLDEMNLATSETLESLSGLFDGGSITLTEKGEVEPVERHPNFKVFACMNPPTDIGKKDLPPGIRNRFTEYYVDDLDNRGDLCLVVKTVLSNLVPNPPIEDIVEFYLKTKQDAQNKMLDGSNQKPIFSLRTLSRALNYTKHVTKSFGFQRALFEGISMSFLTQLNKSSYPMMEQLIKQYIKKGEVKLYNQPLNRPPPTSTTNNNNNNAEESYVKIEQFWIECGNEKPIIPTHYILTPSIKSNLSNIARVLVSRKHPILLQGPTSSGKTSMVEYLAIRTGHRFIRINNHEHTDLQEYLGQYISDDKGKLVFQEGILVEAVRKGYWVVLDELNLAPSEVLEALNRLLDDNRELFIPETQEVVRPHPHFMLFATQNPPGLYGGRKVLSRAFRNRFLELHVDDIPEDELEEILCKRCALPPSYCKKLVLIMKELQLNRQGSNQVFAGKHGAITFRDLFRWAERQPSSYEELGIAGYQLLAERLRKDEEKLIIKQVIEKHLKIKLDIESIYSCDDKPEFLKLLQLLSENDSELSKSNHLEKIVWTRSMKRLFSLVGKCLEHKEPILLVGETGCSKTTICQLYSILNKQKLHILNCHQHTETADFIGGLRPVRGRDQVLSKLYSLVKQYFNQLSQLNLYKLEQENNNIDELPIKEIMERLIVESWKQVSNSSLLTEQLKQLAIEIDKTYSSYCSLFNWVDGPLVEAMKQGDYFLIDEISLAEDAVLERLNSVLEPSRLLVLAEKGGVEIEELRGHKEFRILATMNPGGDFGKKELSPAMRNRFTEIWVPAISSHQDLLQIIEERFTSPQLKGKGSLMLNFIEYLLMIQKNKRVISLRDILSWISFMNLCMDKQLLSPNESYIHGACLVLLDGFGMGSNSSSESEGLKLREACLIRLIDQIESQDEKLKLQTELLSTSSSSSSLSSSIANIIKEENRFGIHPFYIPVRESNVPKIQFSLSAPTTSKNAQRVLRGMQLPRAILVEGSPGVGKTSLITAIANASGNQIVRINLSEQTDIMDLLGSDLPVEGGTGGQFEWRDGVFLEALRNGSWVLLDELNLASQTVLEGLNSCLDHRSEVYIPELGKTFACHPNFRVFACQNPLHQGGGRKGLPKSFLNRFTQVFIDQLNQQDLLFISTAMYPTIPSKTIERMIEFNHQMFKESMIEHKFARKGAPWEFNLRDTFRWCDLIVKDPTSISNPARFIDLIYLQRMRTLQDREHVLTIFKRVFTTSGDENDQSIDMMPTICNYDKQPHYSISPEYLQIGSSILPRVQNGGASSFDSSVLDNSSNIQLLQRLLNPLENIMKCIEMNWMSILIGPTSTSKTSSIRLLAQLTGNTLYEFSMNSSVDTTEILGGFEQIDLVRYQKRIISSVSSLITIVSSHIMTYFNSNDDNLMKTCISSIQDIHQVWNLFKKQTQQTQQQIQQDGATIGSGGVGLITIEQLDLLSTIVDALEKLSIQFNLDNNQEHLNRIQDVRQQIQRIKSIEKESVTGCFEWIDGLLIKALETGAWILIDNVNFCNPTVLDRLNPLLEQDGVLMLNERGMVDGQVKVVKPHPNFRIFLTMDDKKGEISRAMRNRGIEIYMAADQLSLMETPSNNFDNQQLLTALGIPLESLTRTMIDFHNQIFTQLSSTIENPCTLSQLLYWGKLILDQLQRGFSLLNSIRNSMEQIYIRPRRHLTQRQLVTNIFNSIFNESAIKSILCEDQTVLGIYPHFIKGKDYVTDSISTTMKMNYQFFEYYLKRLMNSLSSSSSSSSQQQQQDESNYKISAKFLIENINSSQYENYVLYLNSLKDQNEKDSPINQLLTTLISCMKQLFNHTCYKDFEKRLEQLLSMINLSFIDSKQLLIYQGHQWKNNDSLFLLIKEKVDNYITKEAGGSESMIPIKDLFNQVLLNDMEIIKSLLSLFIQSSKQEKEYNKFLKQVQQGNASQQLSVKSIKSIPVILLSLAYTKKMMSKDLLPHQDIISMIYRLFKSLDEQIDQWLIQLSSSEQQQSTFSTIQIINQLILLKNNFWNSTFNLPSNQFNLGEFIIRWRWIYKEINKLTTLTSKSESPLLINTGLQVLIDKISSGLNQYNNDNSNNRLWKVGGYPMVMKSNHLVQLDSQFLSILEKVQYNFNKNESPIKHSSYAIDEDWKKTLIEAISTLYWANYQLNSDNQNQEQQQQELDRVSEFLTNLELVPQTLSDKLKQLIEKQKQFELNSTFNPVSTNFDNSDISNDSMISDATSIHFDPLSIKHQVISISPLIDHSLHLKETFVISELVKLLMLQHMDIENGKMNQSIITIFESIIDELKYIVNKYKSSTIPRSLYHLAFYQKLIWMIDNYLEKVTTNQEKDEQGQEQEQASIGIIELQSVIHSILYVYNSSQWNNAFNDISHVGKYSLPQYKYRLSKNDAAASLDNGSSKVNIYDSIRFGYGPPRLFQNIQTVFSFYLTCDWEYVSIADVPVKIEQLNQIIQHLTSADGSSNVSNIESFEYQIKQTIALLLSTITSFYKSFNNDEHKKHQLLSNVALIGEHLLSSSSSLEILDIGFDELIENIKELIIQSNDKSFNEKSKQLLLPCLDILLCLDDKVLYKDELKLQSTFGRLQLLLNTFRLIMFVPSGSIDPTQKYDVILQYSKEHSKQLQDEIEIRTIIEKQYTGKDGTSLVIDELVQKKQSIDQKLALDSKKITLRPIPSQFEELYRDVSQFSNHFSNIEKIIDLISKLDLSQVKNEFNLEVESEGGDNQQQQENNTSANSSYNQMILSTEQMWQEKANHFIQSCEKKFYSRYRDIIVPIITAVYQMKSGLRMMSVSFKQKVQDNKLGGNQGITKQIQKVLLSLTQFPRINSVDINSKITTTSTTTTATTTTNTTSNNILLDKLTLDSIKDMMKFNQRTNQDNCNGGLQNFKVIGLLLRSSLCQIYSQLSNSNYLDVDNLEAIDSIFRIFVQEWRFQEEEKRKKEELENQEFKYKVQTHKMETKEEKDEKVFLTSFPNFYKDFEDLEVANVVENQIDDDNDEENKDKENNESNVLTSEDGSMFFKSSINNEEILQLCSIHRDIFKHLDGIPIPKEQQQWTLSDRDRSELFQLFYSSSYLLMKILNQRSGDMEFDQLSLGSHILSASNLKETLSIRPPSLITYSKLDEKFRFLKTSSYLYKKSKGINDDDGDNQVVDVIHQKKTYNIYRDSNISEIGIIREPLISFRKRVFELLVEYPEQANLTLMVKLIDRLMTYPATDPLAKILTGLELLLRKSLEWESFASKAVSIQNHLNEISSLIVRWRKLEIESWPSIFQSQEKEAEVKALKSWFILYDLINDEPSSPELEDENLSKNFHTLQQYLYSSSLGDFLTRIELLKSFYKQLNSTIKLIGTSKNTNYKQKLSDIIYNIFKYFENFISRFEDRLAKSIKPIEDKALEFIRLSRWDDNRLLTQYERLKQHIEVSHRNLAKVTIKYKNVLAQPLHDIFTQIENELDIPPLVLHSGAATILEDKLKKNQKLNKKQIQKKSLAIENFNDWLSFSPSNYSIDRKSIDSISKPIEIESPLLKKLFQIENEKLAQNKLSLLSKRMIQICKENLLESDSWKVVRDGVDIINDLSIEIIDRLKELSSDEKIKRQEKEFALKELMSKFHEMGLSYHINRYPQEQLQISYLFNVRHLPTISDNQGYLPTSFSKITADNGAKLLDQADQYYYRIVSRVHRLRQLSIEYNSDLSSKHVQRINGYVEHFLSIIINQRNNLIDSINSWNHLTLFTELFTNISGSGGSNSEIDEQIFNNHNMLSKWFEIQRESINQFNQAIKEILLLCRKTTSAVSGGMISTIIPEICSIQIIIESIKSEIDKHQSKLRNLFSFLNNQYPMMTWSTINLIISIFTKFKEIKEKLNQLLLSKLSNINYIKSPIQILINNIDSLINKFNSEYEELVGNEINDNDIENQNNIKEFTNQFGILIDQILISIQDLKIQSNQIIAYNKEQEELDQELEKVREYTIEDGSISKLSEFIDHQVQSLRLSKLLEQFVKLHNIIVDGGGSVSTLSIYRQMIKQMGPLLAQFMLIVNQSIVDSLSYHKTCCKLEYISTGVFIQLYSKGFCKPADGGDDGEGGEGGRSNFEDDVEGTGMGEGKGKKDVSDQLEDQGQIEDTNTQKKEEKDEDEDEEKEEKDEDEGFDMQDDFEGEMHDIKKDENKDEDKKDDPNNEKENDKEMGDLEKPEDNVVDEKLWDEQDVQDEEEQDEEGKGDETNSEEMMAKQDGKDDNDDDKKDDDKKDDKKKKKEENGKPDENEEGEEGKDDEEEDGKDDNKNADDGASDEDDFGQEENEDDVINQEQEKEENHGDPRGDDQMEIPEDLELEDPDEGKEDDEQQDGGDDFKDPLDEMDGDDVSKEEEKKKELDGDEKEESDQDGDEEKEDEEKEDGDEDEDKEDKENQPIDPSNVDSINPEGDEPEKEQPEEDQTSLTTNEQQDETPKDSEQPLGVKDKTGSKSNVSNTDEEMKDESNQDNADDDSGMTQPTPSENDTGALKNLKSQPPPQSSAQQPPKKQKQVDPNPYRSMGDANKEWKKRLNLKQEQEEEEEEQSSEPKEKAPKQDPNAKENENQDYEFIKDDEKLDKDEETDQALAAATDTQLQDIPQNKAQDDQAEQEEDQMDIDEEDDMDVDHKQEVEHQDDSKQQLDENKKISMSKLKQDQLKQQKEKEKEKLEKDQQDGQDDELDGLNQKEQFTKEQLENLTNLDKEKAVLDDGDDQEMEQDGDQDDEESVEEKKLTREDLDRMRQELEQYKIENSSNPEIGTELWKKYEQLTNDLSQDLCEQLRLILEPTLATKLQGDYKSGKRINMKKVIPYIASQFKKDKIWLRRTKPNKRQYQVLLAIDDTESMAAYHSGGFALEAMTMISRAMSRLEVGQLGIVRFGEDVQLVHSFDQVFSDQTGPEIITQFKFQQTKTNMVNFLSKTLQIMDMNKQSSSGEPAMQLVFIVSDGWSLRDPETTKKYLREASIKNVFIVFIVIDNPVNNNSILDFESISFNNGKIQRTNYMSEFPFMYYVILRSLNNIPSILSDTLRQWFDLTKSTQ", "length": 5900 }, "evidence": [ { "id": "Q9NU22", "url": "https://omabrowser.org/oma/group/Q9NU22/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q9NU22", "url": "https://www.uniprot.org/uniprotkb/Q9NU22" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "Q9NU22", "url": "https://www.uniprot.org/uniprotkb/Q9NU22" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q9NU22", "url": "https://www.uniprot.org/uniprotkb/Q9NU22" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q9NU22", "url": "https://www.uniprot.org/uniprotkb/Q9NU22" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q9NU22", "url": "https://www.uniprot.org/uniprotkb/Q9NU22" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q9NU22", "url": "https://www.uniprot.org/uniprotkb/Q9NU22" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q9NU22", "url": "https://www.uniprot.org/uniprotkb/Q9NU22" } ], "pmid": "" } ] }, { "name": "Biological Process", 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