[ { "uniprot_canonical_ac": "Q99715-1", "uniprot_ac": "Q99715", "uniprot_id": "COCA1_HUMAN", "mass": { "chemical_mass": 333147.0, "monoisotopic_mass": 333147.0 }, "refseq": { "ac": "NP_004361", "name": "collagen alpha-1(XII) chain long isoform precursor", "summary": "This gene encodes the alpha chain of type XII collagen, a member of the FACIT (fibril-associated collagens with interrupted triple helices) collagen family. Type XII collagen is a homotrimer found in association with type I collagen, an association that is thought to modify the interactions between collagen I fibrils and the surrounding matrix. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_004361" }, "gene_names": [ { "name": "COL12A1", "type": "recommended", "evidence": [ { "id": "Q99715", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q99715" } ] }, { "name": "BA209D8.1", "type": "synonym", "evidence": [ { "id": "NP_004361", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_004361" } ] }, { "name": "BTHLM2", "type": "synonym", "evidence": [ { "id": "NP_004361", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_004361" } ] }, { "name": "COL12A1L", "type": "synonym", "evidence": [ { "id": "NP_004361", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_004361" }, { "id": "Q99715", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q99715" } ] }, { "name": "COL12A1", "type": "synonym", "evidence": [ { "id": "NP_004361", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_004361" } ] }, { "name": "DJ234P15.1", "type": "synonym", "evidence": [ { "id": "NP_004361", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_004361" } ] }, { "name": "EDSMYP", "type": "synonym", "evidence": [ { "id": "NP_004361", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_004361" } ] }, { "name": "UCMD2", "type": "synonym", "evidence": [ { "id": "NP_004361", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_004361" } ] } ], "protein_names": [ { "name": "Collagen alpha-1(XII) chain", "type": "recommended", "evidence": [ { "id": "Q99715", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q99715/entry#names_and_taxonomy" } ] }, { "name": "collagen alpha-1(XII) chain long isoform precursor", "type": "synonym", "evidence": [ { "id": "NP_004361", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_004361" } ] }, { "name": "collagen alpha-1(XII) chain", "type": "synonym", "evidence": [ { "id": "NP_004361", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_004361" } ] }, { "name": "collagen type XII proteoglycan", "type": "synonym", "evidence": [ { "id": "NP_004361", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_004361" } ] }, { "name": "collagen, type XII, alpha 1", "type": "synonym", "evidence": [ { "id": "NP_004361", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_004361" } ] } ], "function": [ { "annotation": "Bioinformatics analysis identified MMP14 and COL12A1 as immune-related biomarkers associated with pancreatic adenocarcinoma prognosis.", "evidence": [ { "database": "RefSeq", "id": "NP_004361", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_004361" }, { "database": "PubMed", "id": "34517516", "url": "https://glygen.org/publication/PubMed/34517516" } ] }, { "annotation": "Epigenetic dysregulation-mediated COL12A1 upregulation predicts worse outcome in intrahepatic cholangiocarcinoma patients. Erratum:[Clin Epigenetics. 2023 Mar 21;15(1):46. doi: 10.1186/s13148-023-01455-3. PMID: 36945022] Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_004361", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_004361" }, { "database": "PubMed", "id": "36694230", "url": "https://glygen.org/publication/PubMed/36694230" } ] }, { "annotation": "PABPC1 promotes cell proliferation and metastasis in pancreatic adenocarcinoma by regulating COL12A1 expression.", "evidence": [ { "database": "RefSeq", "id": "NP_004361", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_004361" }, { "database": "PubMed", "id": "37506150", "url": "https://glygen.org/publication/PubMed/37506150" } ] }, { "annotation": "Temporal profiling of the breast tumour microenvironment reveals collagen XII as a driver of metastasis. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_004361", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_004361" }, { "database": "PubMed", "id": "35933466", "url": "https://glygen.org/publication/PubMed/35933466" } ] }, { "annotation": "This gene encodes the alpha chain of type XII collagen, a member of the FACIT (fibril-associated collagens with interrupted triple helices) collagen family. Type XII collagen is a homotrimer found in association with type I collagen, an association that is thought to modify the interactions between collagen I fibrils and the surrounding matrix. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_004361", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_004361" } ] }, { "annotation": "Type XII collagen interacts with type I collagen-containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix.", "evidence": [ { "database": "UniProtKB", "id": "Q99715", "url": "https://www.uniprot.org/uniprotkb/Q99715#function" }, { "database": "UniProtKB", "id": "D6RGG3", "url": "https://www.uniprot.org/uniprotkb/D6RGG3#function" }, { "database": "UniProtKB", "id": "ARBA00053577", "url": "https://www.uniprot.org/uniprotkb/ARBA00053577#function" }, { "database": "UniProtKB", "id": "H0Y4P7", "url": "https://www.uniprot.org/uniprotkb/H0Y4P7#function" } ] }, { "annotation": "Whole exome sequencing identifies a novel variant in the COL12A1 gene in a family with Ullrich congenital muscular dystrophy 2.", "evidence": [ { "database": "RefSeq", "id": "NP_004361", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_004361" }, { "database": "PubMed", "id": "37458870", "url": "https://glygen.org/publication/PubMed/37458870" } ] } ], "disease": [ { "disease_id": "DOID:0060948", "recommended_name": { "id": "DOID:0060948", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060948", "name": "Ullrich congenital muscular dystrophy 2", "description": "An Ullrich congenital muscular dystrophy characterized by joint hypermobility, proximal contractures, and muscle weakness precluding ambulation that has_material_basis_in homozygous mutation in the COL12A1 gene on chromosome 6q." }, "synonyms": [ { "id": "MONDO:0014654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014654", "name": "Ullrich congenital muscular dystrophy 2", "description": "Any Ullrich congenital muscular dystrophy in which the cause of the disease is a mutation in the COL12A1 gene." }, { "id": "MONDO:0014654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014654", "name": "COL12A1 Ullrich congenital muscular dystrophy", "description": "" }, { "id": "MONDO:0014654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014654", "name": "Ullrich congenital muscular dystrophy 2", "description": "" }, { "id": "MONDO:0014654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014654", "name": "Ullrich congenital muscular dystrophy caused by mutation in COL12A1", "description": "" }, { "id": "MONDO:0014654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014654", "name": "Ullrich congenital muscular dystrophy type 2", "description": "" }, { "id": "MONDO:0014654", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014654", "name": "UCMD2", "description": "" }, { "id": "MIM:616470", "resource": "MIM", "url": "https://www.omim.org/entry/616470", "name": "Ullrich congenital muscular dystrophy 2", "description": "Ullrich congenital muscular dystrophy 2" } ], "unlinked_id_list": [], "evidence": [ { "id": "616470", "database": "MIM", "url": "https://www.omim.org/entry/616470" }, { "id": "0060948", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060948" } ] }, { "disease_id": "DOID:0061201", "recommended_name": { "id": "DOID:0061201", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0061201", "name": "Bethlem myopathy 2", "description": "A Bethlem myopathy characterized by congenital hypotonia, myopathy and delayed motor development with eventual ambulation that has_material_basis_in heterozygous mutation in the COL12A1 gene on chromosome 6q." }, "synonyms": [ { "id": "DOID:0061201", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0061201", "name": "myopathic-type Ehlers-Danlos syndrome", "description": "" }, { "id": "MONDO:0034022", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0034022", "name": "Bethlem myopathy 2", "description": "" }, { "id": "MONDO:0034022", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0034022", "name": "BTHLM2", "description": "" }, { "id": "MONDO:0034022", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0034022", "name": "Bethlem myopathy 2", "description": "" }, { "id": "MONDO:0034022", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0034022", "name": "Bethlem myopathy caused by mutation in COL12A1", "description": "" }, { "id": "MONDO:0034022", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0034022", "name": "Bethlem myopathy type 2", "description": "" }, { "id": "MONDO:0034022", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0034022", "name": "COL12A1 Bethlem myopathy", "description": "" }, { "id": "MONDO:0034022", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0034022", "name": "EDS, myopathic type", "description": "" }, { "id": "MONDO:0034022", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0034022", "name": "Ehlers-Danlos syndrome, myopathic type", "description": "" }, { "id": "MONDO:0034022", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0034022", "name": "myopathic EDS", "description": "" }, { "id": "MONDO:0034022", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0034022", "name": "myopathic Ehlers-Danlos syndrome", "description": "" }, { "id": "MIM:616471", "resource": "MIM", "url": "https://www.omim.org/entry/616471", "name": "Bethlem myopathy 2", "description": "Bethlem myopathy 2" } ], "unlinked_id_list": [], "evidence": [ { "id": "616471", "database": "MIM", "url": "https://www.omim.org/entry/616471" }, { "id": "0061201", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061201" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [ { "tissue": { "name": "Adult mammalian kidney", "namespace": "UBERON", "id": "0000082", "url": "http://purl.obolibrary.org/obo/UBERON_0000082" }, "score": "89.14", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000111799", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000111799" } ] }, { "tissue": { "name": "Oral cavity", "namespace": "UBERON", "id": "0000167", "url": "http://purl.obolibrary.org/obo/UBERON_0000167" }, "score": "91.05", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000111799", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000111799" } ] }, { "tissue": { "name": "Stomach", "namespace": "UBERON", "id": "0000945", "url": "http://purl.obolibrary.org/obo/UBERON_0000945" }, "score": "85.32", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000111799", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000111799" } ] }, { "tissue": { "name": "Esophagus", "namespace": "UBERON", "id": "0001043", "url": "http://purl.obolibrary.org/obo/UBERON_0001043" }, "score": "96.81", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000111799", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000111799" } ] }, { "tissue": { "name": "Rectum", "namespace": "UBERON", "id": "0001052", "url": "http://purl.obolibrary.org/obo/UBERON_0001052" }, "score": "88.73", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000111799", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000111799" } ] }, { "tissue": { "name": "Urinary bladder", "namespace": "UBERON", "id": "0001255", "url": "http://purl.obolibrary.org/obo/UBERON_0001255" }, "score": "92.21", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000111799", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000111799" } ] }, { "tissue": { "name": "Thyroid gland", "namespace": "UBERON", "id": "0002046", "url": "http://purl.obolibrary.org/obo/UBERON_0002046" }, "score": "86.24", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000111799", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000111799" } ] }, { "tissue": { "name": "Liver", "namespace": "UBERON", "id": "0002107", "url": "http://purl.obolibrary.org/obo/UBERON_0002107" }, "score": "77.07", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000111799", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000111799" } ] }, { "tissue": { "name": "Prostate gland", "namespace": "UBERON", "id": "0002367", "url": "http://purl.obolibrary.org/obo/UBERON_0002367" }, "score": "86.27", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000111799", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000111799" } ] }, { "tissue": { "name": "Thoracic mammary gland", "namespace": "UBERON", "id": "0005200", "url": "http://purl.obolibrary.org/obo/UBERON_0005200" }, "score": "94.92", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000111799", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000111799" } ] } ], "expression_disease": [ { "significant": "Yes", "trend": "up", "name": "Prostate cancer [DO disease name]", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "database": "BioXpress", "id": "Q99715", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/Q99715" } ], "disease": [ { "disease_id": "DOID:10283", "recommended_name": { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate." }, "synonyms": [ { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "NGP - new growth of prostate", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "hereditary prostate cancer", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "malignant tumor of the prostate", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "prostate cancer, familial", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "prostate neoplasm", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "prostatic cancer", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "prostatic neoplasm", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "tumor of the prostate", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, hereditary, X-linked 1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "HPCX1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, hereditary, X-linked 1", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "prostate cancer, hereditary, X-linked 2", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "HPCX2", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "prostate cancer, hereditary, X-linked 2", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the RNASEL gene." }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "RNASEL familial prostate cancer", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "familial prostate cancer caused by mutation in RNASEL", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, type 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "HPC1", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, type 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "HPC8", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, type 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, susceptibility to, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "HPC3", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, type 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "HPC4", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, type 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "HPC5", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, type 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "HPC6", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "HPC7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, type 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "HPC9", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "HPC10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the EHBP1 gene." }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "EHBP1 familial prostate cancer", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "familial prostate cancer caused by mutation in EHBP1", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, type 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "HPC12", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the MSMB gene." }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "MSMB familial prostate cancer", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "familial prostate cancer caused by mutation in MSMB", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, type 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "HPC13", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "HPC11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "HPC14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "HPC15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0700275", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0700275", "name": "prostate cancer, hereditary", "description": "An instance of prostate cancer that is caused by an inherited genomic modification in an individual. Familial prostate cancer (FPC) is a malignant tumor of the prostate with an early onset. FPC is either asymptomatic or causes mictionary symptoms, erectile dysfunction, bone pain, venous compression and infectious or inflammatory syndrome (for the metastatic forms). It is also characterized by familial antecedents." }, { "id": "MIM:601518", "resource": "MIM", "url": "https://www.omim.org/entry/601518", "name": "Prostate cancer, hereditary, 1", "description": "Prostate cancer, hereditary, 1" }, { "id": "MIM:610997", "resource": "MIM", "url": "https://www.omim.org/entry/610997", "name": "Prostate cancer, hereditary, 9", "description": "Prostate cancer, hereditary, 9" }, { "id": "MIM:611868", "resource": "MIM", "url": "https://www.omim.org/entry/611868", "name": "Prostate cancer, hereditary, 12", "description": "Prostate cancer, hereditary, 12" }, { "id": "MIM:611928", "resource": "MIM", "url": "https://www.omim.org/entry/611928", "name": "Prostate cancer, hereditary, 13", "description": "Prostate cancer, hereditary, 13" }, { "id": "MIM:611955", "resource": "MIM", "url": "https://www.omim.org/entry/611955", "name": "Prostate cancer, hereditary, 11", "description": "Prostate cancer, hereditary, 11" }, { "id": "MIM:176807", "resource": "MIM", "url": "https://www.omim.org/entry/176807", "name": "Prostate cancer", "description": "Prostate cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ] } ] }, { "significant": "Yes", "trend": "up", "name": "Stomach cancer [DO disease name]", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "database": "BioXpress", "id": "Q99715", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/Q99715" } ], "disease": [ { "disease_id": "DOID:10534", "recommended_name": { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach." }, "synonyms": [ { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "gastric cancer", "description": "" }, { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "A primary or metastatic malignant neoplasm involving the stomach." }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca lesser curvature - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "GC", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "cancer of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer risk after h. pylori infection", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer, somatic", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumor", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumour", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant stomach neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "stomach cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca body - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "ca greater curvature of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of body of stomach", "description": "" }, { "id": "MIM:613659", "resource": "MIM", "url": "https://www.omim.org/entry/613659", "name": "Gastric cancer", "description": "Gastric cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" }, { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ] } ] }, { "significant": "Yes", "trend": "up", "name": "Urinary bladder cancer [DO disease name]", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "database": "BioXpress", "id": "Q99715", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/Q99715" } ], "disease": [ { "disease_id": "DOID:11054", "recommended_name": { "id": "DOID:11054", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder." }, "synonyms": [ { "id": "DOID:11054", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11054", "name": "bladder cancer", "description": "" }, { "id": "DOID:11054", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11054", "name": "tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder cancer", "description": "A primary or metastatic malignant neoplasm involving the bladder." }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "tumour of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "bladder cancer, somatic", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "cancer of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder tumour", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm, bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm, urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor, urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder tumour", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder cancer", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder malignant neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder malignant tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder malignant tumour", "description": "" }, { "id": "MIM:109800", "resource": "MIM", "url": "https://www.omim.org/entry/109800", "name": "Bladder cancer", "description": "Bladder cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ] } ] }, { "significant": "Yes", "trend": "up", "name": "Head and neck cancer [DO disease name]", "url": "https://disease-ontology.org/term/DOID:11934", "evidence": [ { "database": "BioXpress", "id": "Q99715", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/Q99715" } ], "disease": [ { "disease_id": "DOID:11934", "recommended_name": { "id": "DOID:11934", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11934", "name": "head and neck cancer", "description": "An organ system cancer that arises in the head or neck region. This region includes the nasal cavity, sinuses, lips, mouth, salivary glands, throat, or larynx." }, "synonyms": [ { "id": "DOID:11934", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11934", "name": "head and neck neoplasm", "description": "" }, { "id": "DOID:11934", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11934", "name": "head and neck tumours", "description": "" }, { "id": "DOID:11934", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11934", "name": "head/neck neoplasm", "description": "" }, { "id": "DOID:11934", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11934", "name": "tumor of head and neck", "description": "" } ], "unlinked_id_list": [ "DOID:1542" ], "evidence": [ { "id": "11934", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11934" } ] } ] }, { "significant": "Yes", "trend": "up", "name": "Lung cancer [DO disease 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"https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057957", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000057958", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057958", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000057959", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057959", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000057960", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057960", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000057961", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057961", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000057962", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057962", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000057963", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057963", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000057964", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057964", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000057965", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057965", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000057966", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057966", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000057967", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057967", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000057968", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057968", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000057969", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057969", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000057970", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057970", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000057971", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057971", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000057972", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057972", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000057973", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057973", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000057974", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057974", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:000057975", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057975", "database": "PRO", "categories": [ "Glycoproteomics" ] }, { "id": "PR:Q99715", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q99715", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-HSA-1442490", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1442490", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-HSA-1650814", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1650814", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-HSA-2022090", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2022090", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-HSA-8948216", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8948216", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_004361", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_004361", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "GLY_000040", "url": "http://data.glygen.org/GLY_000040", "database": "UniCarbKB", "categories": [] }, { "id": "D6RGG3", "url": "https://www.uniprot.org/uniprotkb/D6RGG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "D6RGG3-1", "url": "https://www.uniprot.org/uniprotkb/D6RGG3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H0Y4P7", "url": "https://www.uniprot.org/uniprotkb/H0Y4P7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H0Y4P7-1", "url": "https://www.uniprot.org/uniprotkb/H0Y4P7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H0Y5N9", "url": "https://www.uniprot.org/uniprotkb/H0Y5N9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H0Y5N9-1", "url": "https://www.uniprot.org/uniprotkb/H0Y5N9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H0Y991", "url": "https://www.uniprot.org/uniprotkb/H0Y991", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H0Y991-1", "url": "https://www.uniprot.org/uniprotkb/H0Y991-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q99715", "url": "https://www.uniprot.org/uniprotkb/Q99715", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q99715-1", "url": "https://www.uniprot.org/uniprotkb/Q99715-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q99715-2", "url": "https://www.uniprot.org/uniprotkb/Q99715-2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q99715-4", "url": "https://www.uniprot.org/uniprotkb/Q99715-4", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRSRLPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYYQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARVGFPKVAIIITDGKSQDEVEIPARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNITTDGYEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGSG", "length": 3063, "header": "sp|Q99715-1|COCA1_HUMAN Isoform 1 of Collagen alpha-1(XII) chain OS=Homo sapiens OX=9606 GN=COL12A1 PE=1 SV=2 CANONICAL=Q99715-1" }, "isoforms": [ { "isoform_ac": "D6RGG3-1", "url": "https://www.uniprot.org/uniprotkb/Q99715/entry#D6RGG3-1", "sequence": { "sequence": "MRSRLPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYYQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARVGFPKVAIIITDGKSQDEVEIPARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNITTDGYEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGTLLPL", "length": 3062, "header": "tr|D6RGG3-1|D6RGG3_HUMAN Computationally mapped isoform of Collagen alpha-1(XII) chain OS=Homo sapiens OX=9606 GN=COL12A1 PE=1 SV=1 CANONICAL=Q99715-1" }, "locus": { "chromosome": "6", "start_pos": 75202792, "end_pos": 75087560, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000483888.6", "url": "https://www.ensembl.org/id/ENST00000483888.6" }, { "database": "Ensembl Peptide", "id": "ENSP00000421216.1", "url": "https://www.ensembl.org/id/ENSP00000421216.1" } ] } }, { "isoform_ac": "H0Y4P7-1", "url": "https://www.uniprot.org/uniprotkb/Q99715/entry#H0Y4P7-1", "sequence": { "sequence": "XKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTPPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNL", "length": 638, "header": "tr|H0Y4P7-1|COCA1_HUMAN Computationally mapped isoform of Collagen alpha-1(XII) chain OS=Homo sapiens OX=9606 GN=COL12A1 PE=1 SV=3 CANONICAL=Q99715-1" }, "locus": { "chromosome": "6", "start_pos": 75152189, "end_pos": 75133376, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000419671.1", "url": "https://www.ensembl.org/id/ENST00000419671.1" }, { "database": "Ensembl Peptide", "id": "ENSP00000393217.1", "url": "https://www.ensembl.org/id/ENSP00000393217.1" } ] } }, { "isoform_ac": "H0Y5N9-1", "url": "https://www.uniprot.org/uniprotkb/Q99715/entry#H0Y5N9-1", "sequence": { "sequence": "VSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNITTDGYEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPEPYVPEGGAYLPEREPFIVPVEPERTAEYEDYGADEPAEEPPEPHRRWRRALPHGPGQ", "length": 756, "header": "tr|H0Y5N9-1|COCA1_HUMAN Computationally mapped isoform of Collagen alpha-1(XII) chain OS=Homo sapiens OX=9606 GN=COL12A1 PE=1 SV=1 CANONICAL=Q99715-1" }, "locus": { "chromosome": "6", "start_pos": 75119473, "end_pos": 75085193, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000425443.6", "url": "https://www.ensembl.org/id/ENST00000425443.6" }, { "database": "Ensembl Peptide", "id": "ENSP00000399812.2", "url": "https://www.ensembl.org/id/ENSP00000399812.2" } ] } }, { "isoform_ac": "H0Y991-1", "url": "https://www.uniprot.org/uniprotkb/Q99715/entry#H0Y991-1", "sequence": { "sequence": "VIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVKT", "length": 207, "header": "tr|H0Y991-1|H0Y991_HUMAN Computationally mapped isoform of Collagen type XII alpha 1 chain OS=Homo sapiens OX=9606 GN=COL12A1 PE=1 SV=1 CANONICAL=Q99715-1" }, "locus": { "chromosome": "6", "start_pos": 75119058, "end_pos": 75113195, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000493109.2", "url": "https://www.ensembl.org/id/ENST00000493109.2" }, { "database": "Ensembl Peptide", "id": "ENSP00000423423.1", "url": "https://www.ensembl.org/id/ENSP00000423423.1" } ] } }, { "isoform_ac": "Q99715-1", "url": "https://www.uniprot.org/uniprotkb/Q99715/entry#Q99715-1", "sequence": { "sequence": "MRSRLPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYYQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARVGFPKVAIIITDGKSQDEVEIPARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNITTDGYEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGSG", "length": 3063, "header": "sp|Q99715-1|COCA1_HUMAN Isoform 1 of Collagen alpha-1(XII) chain OS=Homo sapiens OX=9606 GN=COL12A1 PE=1 SV=2 CANONICAL=Q99715-1" }, "locus": { "chromosome": "6", "start_pos": 75202792, "end_pos": 75086550, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000322507.13", "url": "https://www.ensembl.org/id/ENST00000322507.13" }, { "database": "Ensembl Peptide", "id": "ENSP00000325146.8", "url": "https://www.ensembl.org/id/ENSP00000325146.8" } ] } }, { "isoform_ac": "Q99715-2", "url": "https://www.uniprot.org/uniprotkb/Q99715/entry#Q99715-2", "sequence": { "sequence": "MRSRLPPALAALGAALLLSSIEAEGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNITTDGYEILGKLLKGERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGSG", "length": 1899, "header": "sp|Q99715-2|COCA1_HUMAN Isoform 2 of Collagen alpha-1(XII) chain OS=Homo sapiens OX=9606 GN=COL12A1 PE=1 SV=2 CANONICAL=Q99715-1" }, "locus": { "chromosome": "6", "start_pos": 75202792, "end_pos": 75086550, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000345356.10", "url": "https://www.ensembl.org/id/ENST00000345356.10" }, { "database": "Ensembl Peptide", "id": "ENSP00000305147.9", "url": "https://www.ensembl.org/id/ENSP00000305147.9" } ] } }, { "isoform_ac": "Q99715-4", "url": "https://www.uniprot.org/uniprotkb/Q99715/entry#Q99715-4", "sequence": { "sequence": "MRSRLPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYYQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARVGFPKVAIIITDGKSQDEVEIPARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGSG", "length": 2987, "header": "sp|Q99715-4|COCA1_HUMAN Isoform 4 of Collagen alpha-1(XII) chain OS=Homo sapiens OX=9606 GN=COL12A1 PE=1 SV=2 CANONICAL=Q99715-1" }, "locus": { "chromosome": "6", "start_pos": 75202792, "end_pos": 75086550, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000416123.6", "url": "https://www.ensembl.org/id/ENST00000416123.6" }, { "database": "Ensembl Peptide", "id": "ENSP00000412864.2", "url": "https://www.ensembl.org/id/ENSP00000412864.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "G57321FI", "type": "O-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "TSDPTMSSFR", "relation": "attached", "comment": "Data provided by GlycoDomainViewer", "icn3d_view": {}, "start_pos": 1095, "start_aa": "Thr", "end_pos": 1104, "end_aa": "Arg", "evidence": [ { "id": "23584533", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/23584533" }, { "id": "GLY_000040", "database": "UniCarbKB", "url": "http://data.glygen.org/GLY_000040" }, { "id": "10.1038/emboj.2013.79", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1038/emboj.2013.79" } ], "filter_code": "00000000000000000000.0000000.00000000001000.1000000.0100000000.010100100011111110.10000.xxxxx" }, { "glytoucan_ac": "G57321FI", "type": "O-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "T", "relation": "attached", "comment": "Data provided by GlycoDomainViewer", "icn3d_view": {}, "start_pos": 1099, "start_aa": "Thr", "end_pos": 1099, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1099", "evidence": [ { "id": "23584533", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/23584533" }, { "id": "GLY_000040", "database": "UniCarbKB", "url": 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"evidence": [ { "database": "UniCarbKB", "id": "GLY_000040", "url": "http://data.glygen.org/GLY_000040" }, { "database": "GlyConnect", "id": "1131", "url": "https://glyconnect.expasy.org/browser/proteins/1131" } ], "reference": [ { "type": "PubMed", "id": "29741879", "url": "https://glygen.org/publication/PubMed/29741879" } ] }, { "title": "Allele-specific Alterations in the Peptidome Underlie the Joint Association of HLA-A*29:02 and Endoplasmic Reticulum Aminopeptidase 2 (ERAP2) with Birdshot Chorioretinopathy.", "journal": "Molecular & cellular proteomics : MCP", "date": "2018", "authors": "Sanz-Bravo A, Martin-Esteban A, Kuiper JJW, Garcia-Peydro M, Barnea E, Admon A, Lopez de Castro JA", "evidence": [ { "database": "IEDB", "id": "840108", "url": "https://www.iedb.org/epitope/840108" } ], "reference": [ { "type": "PubMed", "id": "29769354", "url": "https://glygen.org/publication/PubMed/29769354" } ] }, { "title": "Immunopeptidomic Profiling of HLA-A2-Positive Triple Negative Breast 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dissociation from MHC class I using a leucine lever.", "journal": "eLife", "date": "2018", "authors": "Ilca FT, Neerincx A, Hermann C, Marcu A, Stevanovic S, Deane JE, Boyle LH", "evidence": [ { "database": "IEDB", "id": "960099", "url": "https://www.iedb.org/epitope/960099" } ], "reference": [ { "type": "PubMed", "id": "30484775", "url": "https://glygen.org/publication/PubMed/30484775" } ] }, { "title": "Defective co-translational formation of disulphide bonds in protein disulphide-isomerase-deficient microsomes.", "journal": "Nature", "date": "1988", "authors": "Bulleid NJ, Freedman RB", "evidence": [ { "database": "Reactome", "id": "R-HSA-1650814", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1650814" } ], "reference": [ { "type": "PubMed", "id": "3173483", "url": "https://glygen.org/publication/PubMed/3173483" } ] }, { "title": "A large peptidome dataset improves HLA class I epitope prediction across most of the human population.", "journal": "Nature biotechnology", "date": "2020-02", "authors": "Sarkizova Siranush, Klaeger Susan, Le Phuong M, Li Letitia W, Oliveira Giacomo, Keshishian Hasmik, Hartigan Christina R, Zhang Wandi, Braun David A, Ligon Keith L, Bachireddy Pavan, Zervantonakis Ioannis K, Rosenbluth Jennifer M, Ouspenskaia Tamara, Law Travis, Justesen Sune, Stevens Jonathan, Lane William J, Eisenhaure Thomas, Lan Zhang Guang, Clauser Karl R, Hacohen Nir, Carr Steven A, Wu Catherine J, Keskin Derin B", "evidence": [ { "database": "IEDB", "id": "471516", "url": "https://www.iedb.org/epitope/471516" }, { "database": "IEDB", "id": "473251", "url": "https://www.iedb.org/epitope/473251" }, { "database": "IEDB", "id": "476227", "url": "https://www.iedb.org/epitope/476227" }, { "database": "IEDB", "id": "821711", "url": "https://www.iedb.org/epitope/821711" }, { "database": "IEDB", "id": "1012454", "url": "https://www.iedb.org/epitope/1012454" }, { "database": "IEDB", "id": "1013104", "url": "https://www.iedb.org/epitope/1013104" }, { 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Dermot, Huber Florian, Grun Delphine, Leleu Marion, Auger Aymeric, Arnaud Marion, Stevenson Brian J, Michaux Justine, Bilic Ilija, Hirsekorn Antje, Calviello Lorenzo, Sim\u00f3-Riudalbas Laia, Planet Evarist, Lubi\u0144ski Jan, Bry\u015bkiewicz Marta, Wiznerowicz Maciej, Xenarios Ioannis, Zhang Lin, Trono Didier, Harari Alexandre, Ohler Uwe, Coukos George, Bassani-Sternberg Michal", "evidence": [ { "database": "IEDB", "id": "473251", "url": "https://www.iedb.org/epitope/473251" }, { "database": "IEDB", "id": "476227", "url": "https://www.iedb.org/epitope/476227" }, { "database": "IEDB", "id": "481405", "url": "https://www.iedb.org/epitope/481405" }, { "database": "IEDB", "id": "774365", "url": "https://www.iedb.org/epitope/774365" }, { "database": "IEDB", "id": "777772", "url": "https://www.iedb.org/epitope/777772" }, { "database": "IEDB", "id": "1032023", "url": "https://www.iedb.org/epitope/1032023" }, { "database": "IEDB", "id": "1045988", "url": 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by Endoplasmic Reticulum Aminopeptidase 1 (ERAP1).", "journal": "Molecular & cellular proteomics : MCP", "date": "2020-05", "authors": "Chen Liye, Shi Hui, Koftori Danai, Sekine Takuya, Nicastri Annalisa, Ternette Nicola, Bowness Paul", "evidence": [ { "database": "IEDB", "id": "770904", "url": "https://www.iedb.org/epitope/770904" }, { "database": "IEDB", "id": "770913", "url": "https://www.iedb.org/epitope/770913" }, { "database": "IEDB", "id": "1076321", "url": "https://www.iedb.org/epitope/1076321" }, { "database": "IEDB", "id": "1079388", "url": "https://www.iedb.org/epitope/1079388" } ], "reference": [ { "type": "PubMed", "id": "32161166", "url": "https://glygen.org/publication/PubMed/32161166" } ] }, { "title": "Degradation of basement membranes by human matrix metalloproteinase 3 (stromelysin).", "journal": "The Biochemical journal", "date": "1988", "authors": "Bejarano PA, Noelken ME, Suzuki K, Hudson BG, Nagase H", "evidence": [ { "database": "Reactome", "id": 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"https://glygen.org/publication/PubMed/32337544" } ] }, { "title": "In-depth mining of the immunopeptidome of an acute myeloid leukemia cell line using complementary ligand enrichment and data acquisition strategies.", "journal": "Molecular immunology", "date": "2020-07", "authors": "Pandey Kirti, Mifsud Nicole A, Lim Kam Sian Terry C C, Ayala Rochelle, Ternette Nicola, Ramarathinam Sri H, Purcell Anthony W", "evidence": [ { "database": "IEDB", "id": "1372452", "url": "https://www.iedb.org/epitope/1372452" } ], "reference": [ { "type": "PubMed", "id": "32387766", "url": "https://glygen.org/publication/PubMed/32387766" } ] }, { "title": "Solving an MHC allele-specific bias in the reported immunopeptidome.", "journal": "JCI insight", "date": "2020-10-02", "authors": "Klatt Martin G, Mack Kyeara N, Bai Yang, Aretz Zita E H, Nathan Levy I, Mun Sung Soo, Dao Tao, Scheinberg David A", "evidence": [ { "database": "IEDB", "id": "1618835", "url": "https://www.iedb.org/epitope/1618835" } ], "reference": [ { "type": "PubMed", "id": "32897882", "url": "https://glygen.org/publication/PubMed/32897882" } ] }, { "title": "Spliced Peptides and Cytokine-Driven Changes in the Immunopeptidome of Melanoma.", "journal": "Cancer immunology research", "date": "2020-10", "authors": "Faridi Pouya, Woods Katherine, Ostrouska Simone, Deceneux Cyril, Aranha Ritchlynn, Duscharla Divya, Wong Stephen Q, Chen Weisan, Ramarathinam Sri H, Lim Kam Sian Terry C C, Croft Nathan P, Li Chen, Ayala Rochelle, Cebon Jonathan S, Purcell Anthony W, Schittenhelm Ralf B, Behren Andreas", "evidence": [ { "database": "IEDB", "id": "773630", "url": "https://www.iedb.org/epitope/773630" }, { "database": "IEDB", "id": "2000788", "url": "https://www.iedb.org/epitope/2000788" } ], "reference": [ { "type": "PubMed", "id": "32938616", "url": "https://glygen.org/publication/PubMed/32938616" } ] }, { "title": "Biogenesis of HLA Ligand Presentation in Immune Cells Upon Activation Reveals Changes in Peptide Length Preference.", "journal": "Frontiers in immunology", "date": "2020", "authors": "Marino Fabio, Semilietof Aikaterini, Michaux Justine, Pak Hui-Song, Coukos George, M\u00fcller Markus, Bassani-Sternberg Michal", "evidence": [ { "database": "IEDB", "id": "1280964", "url": "https://www.iedb.org/epitope/1280964" } ], "reference": [ { "type": "PubMed", "id": "32983136", "url": "https://glygen.org/publication/PubMed/32983136" } ] }, { "title": "The Impact of Biomaterial Cell Contact on the Immunopeptidome.", "journal": "Frontiers in bioengineering and biotechnology", "date": "2020", "authors": "Ghosh Michael, Hartmann Hanna, Jakobi Meike, M\u00e4rz L\u00e9o, Bichmann Leon, Freudenmann Lena K, M\u00fchlenbruch Lena, Segan S\u00f6ren, Rammensee Hans-Georg, Schneiderhan-Marra Nicole, Shipp Christopher, Stevanovi\u0107 Stefan, Joos Thomas O", "evidence": [ { "database": "IEDB", "id": "1340999", "url": "https://www.iedb.org/epitope/1340999" } ], "reference": [ { "type": "PubMed", "id": "33392160", "url": "https://glygen.org/publication/PubMed/33392160" } ] }, { "title": "CIITA-Transduced Glioblastoma Cells Uncover a Rich Repertoire of Clinically Relevant Tumor-Associated HLA-II Antigens.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Forlani Greta, Michaux Justine, Pak HuiSong, Huber Florian, Marie Joseph Elodie Lauret, Ramia Elise, Stevenson Brian J, Linnebacher Michael, Accolla Roberto S, Bassani-Sternberg Michal", "evidence": [ { "database": "IEDB", "id": "473251", "url": "https://www.iedb.org/epitope/473251" }, { "database": "IEDB", "id": "476227", "url": "https://www.iedb.org/epitope/476227" }, { "database": "IEDB", "id": "484997", "url": "https://www.iedb.org/epitope/484997" }, { "database": "IEDB", "id": "774365", "url": "https://www.iedb.org/epitope/774365" }, { "database": "IEDB", "id": "960099", "url": "https://www.iedb.org/epitope/960099" }, { "database": "IEDB", "id": "1021921", "url": "https://www.iedb.org/epitope/1021921" }, { 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Immunopeptidome by Flucloxacillin and Immunogenicity of Drug-Haptenated Peptides.", "journal": "Frontiers in immunology", "date": "2020", "authors": "Puig Montserrat, Ananthula Suryatheja, Venna Ramesh, Kumar Polumuri Swamy, Mattson Elliot, Walker Lacey M, Cardone Marco, Takahashi Mayumi, Su Shan, Boyd Lisa F, Natarajan Kannan, Abdoulaeva Galina, Wu Wells W, Roderiquez Gregory, Hildebrand William H, Beaucage Serge L, Li Zhihua, Margulies David H, Norcross Michael A", "evidence": [ { "database": "IEDB", "id": "1745054", "url": "https://www.iedb.org/epitope/1745054" } ], "reference": [ { "type": "PubMed", "id": "33633747", "url": "https://glygen.org/publication/PubMed/33633747" } ] }, { "title": "Carbamazepine Induces Focused T Cell Responses in Resolved Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Cases But Does Not Perturb the Immunopeptidome for T Cell Recognition.", "journal": "Frontiers in immunology", "date": "2021", "authors": "Mifsud Nicole A, Illing Patricia T, Lai 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5-azacytidine augments presentation of immunogenic frameshift-derived neoepitopes.", "journal": "iScience", "date": "2021-04-23", "authors": "Becker Jonas P, Helm Dominic, Rettel Mandy, Stein Frank, Hernandez-Sanchez Alejandro, Urban Katharina, Gebert Johannes, Kloor Matthias, Neu-Yilik Gabriele, von Knebel Doeberitz Magnus, Hentze Matthias W, Kulozik Andreas E", "evidence": [ { "database": "IEDB", "id": "476227", "url": "https://www.iedb.org/epitope/476227" }, { "database": "IEDB", "id": "1032023", "url": "https://www.iedb.org/epitope/1032023" }, { "database": "IEDB", "id": "1045988", "url": "https://www.iedb.org/epitope/1045988" }, { "database": "IEDB", "id": "1715352", "url": "https://www.iedb.org/epitope/1715352" } ], "reference": [ { "type": "PubMed", "id": "33981976", "url": "https://glygen.org/publication/PubMed/33981976" } ] }, { "title": "The Effect of Interferons on Presentation of Defective Ribosomal Products as HLA Peptides.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Komov Liran, Melamed Kadosh Dganit, Barnea Eilon, Admon Arie", "evidence": [ { "database": "IEDB", "id": "1290186", "url": "https://www.iedb.org/epitope/1290186" }, { "database": "IEDB", "id": "1555614", "url": "https://www.iedb.org/epitope/1555614" } ], "reference": [ { "type": "PubMed", "id": "34087483", "url": "https://glygen.org/publication/PubMed/34087483" } ] }, { "title": "Profiling SARS-CoV-2 HLA-I peptidome reveals T\u00a0cell epitopes from out-of-frame ORFs.", "journal": "Cell", "date": "2021-07-22", "authors": "Weingarten-Gabbay Shira, Klaeger Susan, Sarkizova Siranush, Pearlman Leah R, Chen Da-Yuan, Gallagher Kathleen M E, Bauer Matthew R, Taylor Hannah B, Dunn W Augustine, Tarr Christina, Sidney John, Rachimi Suzanna, Conway Hasahn L, Katsis Katelin, Wang Yuntong, Leistritz-Edwards Del, Durkin Melissa R, Tomkins-Tinch Christopher H, Finkel Yaara, Nachshon Aharon, Gentili Matteo, Rivera Keith D, Carulli Isabel P, Chea Vipheaviny A, Chandrashekar Abishek, Bozkus Cansu Cimen, Carrington Mary, , Bhardwaj Nina, Barouch Dan H, Sette Alessandro, Maus Marcela V, Rice Charles M, Clauser Karl R, Keskin Derin B, Pregibon Daniel C, Hacohen Nir, Carr Steven A, Abelin Jennifer G, Saeed Mohsan, Sabeti Pardis C", "evidence": [ { "database": "IEDB", "id": "1626109", "url": "https://www.iedb.org/epitope/1626109" } ], "reference": [ { "type": "PubMed", "id": "34171305", "url": "https://glygen.org/publication/PubMed/34171305" } ] }, { "title": "Proteogenomic identification of an immunogenic HLA class I neoantigen in mismatch repair-deficient colorectal cancer tissue.", "journal": "JCI insight", "date": "2021-07-22", "authors": "Hirama Tomomi, Tokita Serina, Nakatsugawa Munehide, Murata Kenji, Nannya Yasuhito, Matsuo Kazuhiko, Inoko Hidetoshi, Hirohashi Yoshihiko, Hashimoto Shinichi, Ogawa Seishi, Takemasa Ichiro, Sato Noriyuki, Hata Fumitake, Kanaseki Takayuki, Torigoe Toshihiko", "evidence": [ { "database": "IEDB", "id": "471516", 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} ] }, { "title": "Endostatin: an endogenous inhibitor of angiogenesis and tumor growth.", "journal": "Cell", "date": "1997", "authors": "O'Reilly MS, Boehm T, Shing Y, Fukai N, Vasios G, Lane WS, Flynn E, Birkhead JR, Olsen BR, Folkman J", "evidence": [ { "database": "Reactome", "id": "R-HSA-2022090", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2022090" } ], "reference": [ { "type": "PubMed", "id": "9008168", "url": "https://glygen.org/publication/PubMed/9008168" } ] }, { "title": "Cloning and characterization of a novel human lysyl hydroxylase isoform highly expressed in pancreas and muscle.", "journal": "The Journal of biological chemistry", "date": "1997", "authors": "Valtavaara M, Papponen H, Pirttila AM, Hiltunen K, Helander H, Myllyla R", "evidence": [ { "database": "Reactome", "id": "R-HSA-1650814", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1650814" } ], "reference": [ { "type": "PubMed", "id": "9054364", "url": "https://glygen.org/publication/PubMed/9054364" } ] }, { "title": "Expression of three membrane-type matrix metalloproteinases (MT-MMPs) in rat vascular smooth muscle cells and characterization of MT3-MMPs with and without transmembrane domain.", "journal": "The Journal of biological chemistry", "date": "1997", "authors": "Shofuda K, Yasumitsu H, Nishihashi A, Miki K, Miyazaki K", "evidence": [ { "database": "Reactome", "id": "R-HSA-1442490", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1442490" } ], "reference": [ { "type": "PubMed", "id": "9092507", "url": "https://glygen.org/publication/PubMed/9092507" } ] }, { "title": "Complete primary structure of two splice variants of collagen XII, and assignment of alpha 1(XII) collagen (COL12A1), alpha 1(IX) collagen (COL9A1), and alpha 1(XIX) collagen (COL19A1) to human chromosome 6q12-q13.", "journal": "Genomics", "date": "1997", "authors": "Gerecke D R, Olson P F, Koch M, Knoll J H, Taylor R, Hudson D L, Champliaud M F, Olsen B R, Burgeson R E", "evidence": [ { "database": "UniProtKB", "id": "Q99715", "url": "https://www.uniprot.org/uniprotkb/Q99715" } ], "reference": [ { "type": "PubMed", "id": "9143499", "url": "https://glygen.org/publication/PubMed/9143499" } ] }, { "title": "Type XII collagen contributes to diversities in human corneal and limbal extracellular matrices.", "journal": "Invest. Ophthalmol. Vis. Sci.", "date": "1997", "authors": "Wessel H, Anderson S, Fite D, Halvas E, Hempel J, SundarRaj N", "evidence": [ { "database": "UniProtKB", "id": "Q99715", "url": "https://www.uniprot.org/uniprotkb/Q99715" } ], "reference": [ { "type": "PubMed", "id": "9344363", "url": "https://glygen.org/publication/PubMed/9344363" } ] }, { "title": "Protein disulfide isomerase acts as a molecular chaperone during the assembly of procollagen.", "journal": "The Journal of biological chemistry", "date": "1998", "authors": "Wilson R, Lees JF, Bulleid NJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-1650814", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1650814" } ], "reference": [ { "type": "PubMed", "id": "9545296", "url": "https://glygen.org/publication/PubMed/9545296" } ] }, { "title": "Thiol-independent interaction of protein disulphide isomerase with type X collagen during intra-cellular folding and assembly.", "journal": "The Biochemical journal", "date": "1998", "authors": "McLaughlin SH, Bulleid NJ", "evidence": [ { "database": "Reactome", "id": "R-HSA-1650814", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1650814" } ], "reference": [ { "type": "PubMed", "id": "9560306", "url": "https://glygen.org/publication/PubMed/9560306" } ] }, { "title": "Primary structure, tissue distribution, and chromosomal localization of a novel isoform of lysyl hydroxylase (lysyl hydroxylase 3)", "journal": "The Journal of biological chemistry", "date": "1998", "authors": "Valtavaara M, Szpirer C, Szpirer J, Myllyla R", "evidence": [ { "database": "Reactome", "id": "R-HSA-1650814", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1650814" } ], "reference": [ { "type": "PubMed", "id": "9582318", "url": "https://glygen.org/publication/PubMed/9582318" } ] }, { "title": "Cloning and characterization of a novel matrix metalloproteinase (MMP), CMMP, from chicken embryo fibroblasts. CMMP, Xenopus XMMP, and human MMP19 have a conserved unique cysteine in the catalytic domain.", "journal": "The Journal of biological chemistry", "date": "1998", "authors": "Yang M, Kurkinen M", "evidence": [ { "database": "Reactome", "id": "R-HSA-1442490", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1442490" } ], "reference": [ { "type": "PubMed", "id": "9651395", "url": "https://glygen.org/publication/PubMed/9651395" } ] }, { "title": "The chick and human collagen alpha1(XII) gene promoter -- activity of highly conserved regions around the first exon and in the first intron.", "journal": "Eur. J. Biochem.", "date": "1998", "authors": "Chiquet M, Mumenthaler U, Wittwer M, Jin W, Koch M", "evidence": [ { "database": "UniProtKB", "id": "Q99715", "url": "https://www.uniprot.org/uniprotkb/Q99715" } ], "reference": [ { "type": "PubMed", "id": "9826181", "url": "https://glygen.org/publication/PubMed/9826181" } ] }, { "title": "Interaction of BP180 (type XVII collagen) and alpha6 integrin is necessary for stabilization of hemidesmosome structure.", "journal": "The Journal of investigative dermatology", "date": "1998", "authors": "Hopkinson SB, Findlay K, deHart GW, Jones JC", "evidence": [ { "database": "Reactome", "id": "R-HSA-2022090", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2022090" } ], "reference": [ { "type": "PubMed", "id": "9856810", "url": "https://glygen.org/publication/PubMed/9856810" } ] } ], "pathway": [ { "id": "hsa:1303", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?hsa:1303", "resource": "KEGG Pathway" }, { "id": "R-HSA-1442490", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1442490", "resource": "Reactome", "description": "Collagen degradation" }, { "id": "R-HSA-1650814", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1650814", "resource": "Reactome", "description": "Collagen biosynthesis and modifying enzymes" }, { "id": "R-HSA-2022090", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-2022090", "resource": "Reactome", "description": "Assembly of collagen fibrils and other multimeric structures" }, { "id": "R-HSA-8948216", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-8948216", "resource": "Reactome", "description": "Collagen chain trimerization" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1L1RPW4-1", "protein_name": "Collagen alpha-1(XII) chain", "gene_name": "COL12A1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRTALCSAVAALCAAALLSSIEAEVNPPSDLNFTIIDEHNVQMSWKRPPDAIVGYRITVVPTNDGPTKEFTLSPSTTQTVLSDLIPEIEYVVSIASYDEVEESLPVFGQLTIQTGGPGIPEEKKVEAQIQKCSISAMTDLVFLVDGSWSVGRNNFRYILDFMVALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYFRRSDLLDAIKRIPYKGGNTMTGEAIDYLVKNTFTESAGARKGFPKVAIVITDGKAQDEVEIPARELRNIGVEVFSLGIKAADAKELKLIASQPSLKHVFNVANFDGIVDIQNEIILQVCSGVDEQLGELVSGEEVVEPASNLVATQISSKSVRITWDPSTSQITGYRVQFIPMIAGGKQHVLSVGPQTTALNVKDLSPDTEYQINVYAMKGLTPSEPITIMEKTQQVKVQVECSRGVDVKADVVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPRKVQISLVQYSRDPHMEFSLNRYNRVEDIIQAINTFPYRGGSTNTGKAMTYVREKVFVTSKGSRPNVPRVMILITDGKSSDAFKEPAIKLRDADVEIFAVGVKDAVRTELEAIASPPAETHVYTVEDFDAFQRISFELTQSVCLRIEQELAAIRKKSYVPAKNMVFSDVTSDSFKVSWSAAGSEVLSYLIKYKVAIGGDEFIVSVPASSTSSVLTNLLPETTYAVSVIAEYEDGDGPPLDGEETTLEVKGAPRNLRITDETTDSFIVGWTPAPGNVLRYRLVYRPLTGGERRQVTVSANERSTTLRNLIPDTRYEVSVIAEYQSGPGNALNGYAKTDEVRGNPRNLRVSDATTSTMKLSWSAAPGKVQQYFITYTPVAGGETKELTVKGDTTSKVLKGLDEATRYALTVSALYASGAGEALSGEGETLEERGSPRNLITTDITDTTVGLSWTPAPGTVNNYRIVWKSLYDDTMGEKRVPGNTVDAVLDGLEPETKYRISVYAAYSSGEGDPVEGEAFTDVSQSARTVTVDNETENTMRVSWQPSPGKVLSYRVYYRPRSGGRQMFGKVNASATSIVLKRLKPRTTYDLSVVPIYDFGQGKSRKAEGTTASPFKPPRNLRTSDSTMSSFRVTWEPAPGRVKGYKVTFHPTEDDRNLGELIVGPYDSTVVLEELRAGTTYKVNVFGMFDGGESNPLVGQEMTTLSDTTTEPFLSRGLECRTRAEADIVLLVDGSWSIGRPNFKTVRNFISRIVEVFDIGPDKVQIGLAQYSGDPRTEWNLNAYRTKEALLEAVTNLPYKGGNTLTGMALDFILKNNFKQEAGLRPRARKIGVLITDGKSQDDVVTPSRRLRDEGVELYAIGIKNADENELKQIATDPDDIHAYNVADFSFLASIVEDVTTNLCNSVKGPGDLPPPSNLVISEVTPHSFRLRWSPPPESVDRYRVEYYPTTGGPPKQFYVSRMETTTVLKDLTPETEYIVNVFSVVEDESSEPLIGREITYPLSSVRNLNVYDIGSTSMRVRWEPVNGATGYLLTYEPVNATVPTTEKEMRVGPSVNEVQLVDLIPNTEYTLTAYVLYGDITSDPLTSQEVTLPLPGPRGVTIRDVTHSTMNVLWDPAPGKVRKYIIRYKIADEADVKEVEIDRLKTSTTLTDLSSQRLYNVKVVAVYDEGESLPVAAEAVTQPVPSPVNLRITEITKNSFRGTWDHGAPDVSLYRITWGPYGRSEKAESIVNGDVNSLLFENLNPDTLYEVSVTAIYPDESESDDLIGSERTLPLVPITTPAPKSGPRNLQVYNATSHSLTVKWDPASGRVQRYKIIYQPINGDGPEQSTMVGGRQNSVVIQKLQPDTPYAITVSSMYADGEGGRMTGRGRTKPLTTVKNMLVYDPTTSTLNVRWDHAEGNPRQYKVFYRPTAGGAEEMTTVPGNTNYVILRSLEPNTPYTVTVVPVFPEGDGGRTTDTGRTLERGTPRNIQVYNPTPNSMNVRWEPAPGPVQQYRVNYSPLSGPRPSESIVVPANTRDVMLERLTPDTAYSINVIALYADGEGNPSQAQGRTLPRSGPRNLRVFDETTNSLSVQWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGIRNNVILQPLQSDTPYKITVVAVYEDGDGGQLTGNGRTVGLLPPQNIYITDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEVFVGEVTSYTLHNLSPSTTYDVNVYAQYDSGMSIPLTDQGTTLYLNVTDLTTYKIGWDTFCIRWSPHRSATSYRLKLNPADGSRGQEITVRGSETSHCFTGLSPDTEYNATVFVQTPNLEGPPVSVREHTVLKPTEAPTPPPTPPPPPTIPPARDVCRGAKADIVFLTDASWSIGDDNFNKVVKFVFNTVGAFDLINPAGIQVSFVQYSDEAKSEFKLNTFDDKAQALGALQNVQYRGGNTRTGKALTFIKEKVLTWESGMRRGVPKVLVVVTDGRSQDEVRKAATVIQHSGFSVFVVGVADVDYNELAKIASKPSERHVFIVDDFDAFEKIQDNLVTFVCETATSTCPLIYLEGYTSPGFKMLESYNLTEKHFASVQGVSLESGSFPSYVAYRLHKNAFVSQPIREIHPEGLPQAYTIIMLFRLLPESPSEPFAIWQITDRDYKPQVGVVLDPGSKVLSFFNKDTRGEVQTVTFDNDEVKKIFYGSFHKVHIVVTSSNVKIYIDCSEILEKPIKEAGNITTDGYEILGKLLKGDRRSATLEIQNFDIVCSPVWTSRDRCCDLPSMRDEAKCPALPNACTCTQDSVGPPGPPGPAGGPGAKGPRGERGLTGSSGPPGPRGETGPPGPQGPPGPQGPNGLSIPGEPGRQGMKGDAGQPGLPGRSGTPGLPGPPGPVGPPGERGFTGKDGPTGPRGPPGPAGAPGVPGVAGPSGKPGKPGDRGTPGTPGMKGEKGDRGDIASQNMMRAVARQVCEQLINGQMSRFNQMLNQIPNDYYSNRNQPGPPGPPGPPGAAGTRGEPGPGGRPGFPGPPGVQGPPGERGMPGEKGERGTGSQGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNAGIRGPPGPPGYCDSSQCASIPYNGQGFPEPYVPESGPYQPEGEPFIVPMESERREDEYEDYGVEMHSPEYPEHMRWKRSLSRKAKRKP", "length": 3122 }, "evidence": [ { "id": "Q99715", "url": "https://omabrowser.org/oma/group/Q99715/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8M6YUY1-1", "protein_name": "Collagen alpha-1(XII) chain", "gene_name": "col12a1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVRHLAAVALFTLAALTSVRAQVMPPSDLRFKILNENTVQMTWKQPLSRVDGFRVQVTSDTEEPVKEFTLSPTSTKTSIRDLTPDVDYVVTITSYLGSEESIPISGQITIQSSGFEGGTRKPQVSDAVKCSIGAIADLVFLVDGSWSVGRENFKFIRNFIAALAGAFDLGEDKTRVGVVQYSTDTRTEFNLNQHFRRVDLLRAINNLPYKGGNTMTGEALDYLLKNMFTEAAGARKGFPRVAVVITDGKSQDPVEGYAKKLKNAGVELFTLGIKEADEEELKQMSSTPYRTHVYTVPNFDMIKAVEKSFIAQVCSSVDDQLNSLASGEEVVEPASNLQVTEVASKSMRVTWDASIGEVTGYKVQMVPMLAGSKRQELYVGPTQTSVNVRDLSPDTEYEISLFALKGLTPSEAVMAMEKTQPLKVSLECSLGVDVQADIVLLVDGSYSIGITNFAKVRAFLEVLVNTFDIGPNKVQISLVQYSRDPYTEFYLNTHHDLNAVVKAVRTFPYRGGSTNTGKAMTYVRERIFIATRGARENVPRVTILITDGKSSDAFKDPAAKLRNTDVEIFAVGVKDAVRSELEAIANPPAETHVYTVEDFDAFQRISNELTQSICLRIEQELLNIKRRSLVAPRSLTLSEVTSRSFRASWEIDAVDVQAYLVQYKPDADAEASYTSVSIPGDSTTTVLYHLTPVTKYEVKVYAQYEKGESFPLSGYETTLDELGSVTNLKVSEETSSSFRVSWREAPGPVVRYRLTYIPVQGDSGLLETATVGPETTIVLQQLYPVTTYRVSVAAEYPSGVGPQMQIDGTTKEELGSPRDLRVSDETVSSMQLSWAAAPGRVLQYSVFYQSTITAVTKAVTLKGDTTSTMLKNLEPGTEYNLSVSARYSSGQGASLQGVGTTLEELGSPRDLITSDVTDTSFMVSWTAAPGRVRQYLVRWRSLFSGESGEKLVPGDVTSTLLENLSPETRYQVSVFAAYDRGNGEPLVGEETTDASASAKALLVSDETERTMRVIWKAAPGPVVNYRLTYIPQTGGKEMTMKIPANVTSTMLRKLQHTTTYFITVHPIYKRGEGKARQGVGTTLSPYKAPRNLQTSEPTKTSFRVTWDPAPGDVRGYKVTFHPSENDIDLGELLVGPYDNTVVLEELRAGTKYSVAVFGMFDGGQSMPLAGEEKTTLSDAPDSPPVKYSGNECKTSAKADIVLLVDGSWSIGRLNFKTIRAFIGRMVGVFDIGPDKVQIGLAQYSGDPKTEWHLNAHPTRASLLDAVANLPYKGGNTMTGMALNYILQNNFRPNVGMRPDSRKIGVLVTDGKSQDEIVVNSQRLRDSGIELYAIGVKNADENELRSIATDPDEIHMYNVNDFSFLLDIVDDLTENLCNSVKGPGGGPGTPTDLETSEVTHYSFRATWMPPDEPVERFRIEYVPAAGGKTEVLFVDGEENTLVLVNLNPMTEYIVRVYGVIGEESSEPLKGTETTLPLPAVTSMSVYDEALTSMRVRWELVKGASGYLLNYNAINASVPSGMMEMRVGADVNDVQLLQLLPNTAYSISLFALHGEAASQPLIDRGVTLPLPPAGKLKITEVTHSSMRLTWDAAPGNVRKYIITYKREDGELKELEVNGDITTMVLTNLRSQTEYDVAVTPVYDEGSGNPMLGTAITDVVPAPKNLRFSEVGQTSFRATWEHGAPDVGMYRIGWSKKGDRENVKSEILAREETSHLLTELDPDTEYDVTVTAIYPDESESEDLMGSQRTLSKLITPVPTGPPQNLQVFNATTTTLTVKWDHAPGPVQSYKVTHQPVAGGKPLSVQVGGKKNSVILQKLTPNTPYTITVAAVYRTGESKDISGQGRTKPLGGVRNLQVLNPTMTTLNVRWEPAEGKVKEYKVVYVPAAGGAESMVGLEQVSGATTNTVLRGLQSDTLYTVTLIPVYAEGEGQRMSENGKTRALGGVKNLRVTDPTMTSLNVKWDPADGAVRQYKIFFVPAAGGTEAMETVPGPQNTIVLRNLQPDTVYTVSVVPVYPATEGRRQSENGKTLPLGGVRNLRLIDPTFTTLTATWEAADGNVQGYKVIYVPTGGGTELMEQVSESTTTLVLQKLMPDTMYTVTVLPVYAEGDGPRLSEKGKTKPLGSVRNLQVTDPTISTLNVRWEPAEGNVREYIVIYVPAGSQDQEVDQVPGTTTSTVLKNLEPDTTYTVTLVPVYHEMEGKSLSENGKTKPLGGVRNLQVTDPTSSTLNVRWEHADGNPRNYKVFYIPQPGDAEMMELVSGGTTSTVLRNLNANTMYKVTLLPMYENDVEGKRQSENGKTKPLGSVKNLQVTDPTVNSLRVRWDAADGDVRQYNVIYVPVAGGAAGQTQVSGMSTNTILRNLQPNTEYKVTVVPVYADAEGKRQSANGKTKPLGGVKNLQVTDPTTSSLKVRWEPAEGNVRQYRIFYVPASGGAEDMEQVSGGTTNTILRNLLSDTVYTVTVVPVYPEGEGLRQSEKGKTLPRLPPRNIKVYNPTPNSLNVRWEPASGQVQQYRVAYAPLTGIRPLESVLVPGNLNNAFLDQLVPDTPYSVNVMAVYADGEGPGIDGNGKTLPRAGPRNMRVFETTTSTISIGWDHAEGPVQQYKISYASLTGDPITEFTVVPGNRNNAMLQNLHPDTPYNITVTAVYPEGPGGSLNGNGKTLGLLAPQNLRVSDEWYTRFRVSWDPAPSPVMGYKLVYQPTTKDESLEVFVGDVTSYTLHNLLPGTTYDVQVYAQYDGGVSKPLIGQGTTLYLNVTNLESYDVGYNRFCIKWTPHRAATSYRIKLNPVDPSAKGQQEITITASQSQYCFEGLSQDSLYTATVFVQTPNLEGPGVGTKERTRVKPTPVPTKPPTPPPPPTIPPGWAVCKGAKADVVFLIDGSWSIGDESFSKVIQFVFSVVGAFDVIGPTGMQISFVQYSDDANTEFRLNTYKDKGTALSALKLIRYQGGNTKTGVALKHVYEKVITVENGMRRNVPKVVVAVTDGRSQDDVHKNAAKLQHAGYSVFVVGVADVDFVELQNIASKPSERHVFVVDDFDAFSTIQDNLVTFICETATSSCPLIYVNGFTSPGFRMLEAFNLTEKMYASTKGVSMEPGSFNSYTAYRLHKNAFLSQPSSYIHPDGLPSTYTIILMFRLLPDSPNEAFDIWQVSDKNYKPETGVTIDPSAQSVSFYNKDTTGEIQRATFKNDQVKRIFHGSFHKLHILVSSKSVKLNVDCHEVAEKEIKPAGNTSTDGFQVLGKMSKSIGSKGESATFQLQMFDIVCSLGWTSRDRCCDLPSMRDESKCPALPNACTCTSDSSGPPGPQGPVGAPGSKGPRGERGEPGQVGPVGTRGEMGMPGPMGPPGPQGPSGRSIPGEAGRQGPKGDPGDAGLPGQKGPPGPTGAIGPVGPAGIRGPPGKEGPVGPMGPQGAMGPPGAPGMPGPAGKPGKNGDTGVPGLTGVKGDKGERGDIASQSMMRSIARQVCEQLVNGQMGRFNDMFNQIPSNYHSNSPGPSGPPGPPGPQGPRGEPGRLGRNGLPGSPGLPGRQGERGTPGEKGERGSPGVGERGQRGPSGPPGPPGESRTGPTGSSGPPGIRGPPGRNGVAGVRGPPGPPGYCDSSMCVSMQYNGQGYREEFPPDAERVVPIPDEDFEISANQRRRRSPPETGPKRKAW", "length": 3653 }, "evidence": [ { "id": "HGNC:2188", "url": "https://alliancegenome.org/gene/HGNC:2188#orthology", "database": "AGR" }, { "id": "RGD:2374", "url": "https://alliancegenome.org/gene/RGD:2374#orthology", "database": "AGR" }, { "id": "MGI:88448", "url": "https://alliancegenome.org/gene/MGI:88448#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120215-116", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-116#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TBL0-1", "protein_name": "Collagen alpha-1(XII) chain", "gene_name": "col12a1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKIRLSLAAAALLTLVLSSVEAQVEPPSDLKFKILNENTVQMSWRKPSSQIQGYRIQVTSDTDDSKELSLPASSTSTSITDLTPDVDYSVSINSYDGAEESIPILGQITIQSSNTSGPRRPQSEAVKCSVSAVADLVFLVDGSWSVGRENFRFIRSFIGAMAGAFDIEEDKTRVAVVQYSSDTRTEFSLNTHFRRPDVLRAIKNLPYKGGNTMTGDAMDYLVKNTFTQAAGARKGFPKVAMIITDGKSQDPVEEYAERLRNIGVEIFVLGIKGADEDELKEIASRPHSKHVYNVPNFDMINQVQKALITEVCSGVEEQLNSLVSGEEVVEPASNLRVTDISSKSMRIAWDSSPGDITGYKLQVFPTIASAKKQELYTGPTMTLANVRDLTPEMEYEISLFALKGLTPSVPQVVTEKTQPVKVFTECSLEVDVQADIVLLVDGSYSIGLPNFAKVRAFLEVLVNSFDIGPNKVQISLVQYSRDPHTEFALNKFDDNAAMVKAVRTFPYRGGSTNTGKAMTYVREKIFVSGRGARDNVPRVMVLITDGKSSDSFKDPANKLRDTDVEIFAVGVKDAVRSELEAIANVPADNHVFEVEDFDAFERISKELTASICLRIEQELHNIRKRSLLPPKSLSFSEVTSRSFRTSWVSDGEDILSFLVRFRPAADLTGDYISLVVPHDITSTILPNLTPLTTYEVNVIAQYDKGDSFPLTGEETTLEELGSVRNLMVSEEAVDRFRVSWRAAPGLVLRYRLLYEPVSGGDKLEAETDGNQVTTVLNELLPVTTYRVTVYPEYASGRGPSMDTEGTTKEVRGSPRDLRVFNETVSSMRVSWRAAPGNVLQYQVAYKPDGGERKEISVKGETTTAVLKNLLPDTEYELFVSARYVSGLGAPLMGTGTTLEELGSPSNLVTSDVTENSFVASWTAAPGNVRLYRVTWKSLFSEEAGEKTVPGDVTTTVLDGLTPETRYKVSVYAVYSRAEGAPLHGEETTDVSAATRALTVSEETERTMKVTWIPAPGNVVNYRVSYKPQGDLRQMASKAPGGTNSIVLRRLIPQTTYDITVVPVYKFGDGRQRQGEGTTLSQYKAPRNLQTSEPTKTSFRVTWDHAPGDVKGYKVTFHPTGKEVDLGELLVGPYDNTVVLEELRAGTKYTVNVFGMFDGGESMPLAGEEKTTLSDAASENLPYTPSDAQCKTTAQADIVLLVDGSWSIGRLNFKTIRNFIARMVGVFDIGPDRVQIGLAQYSGDPKTEWHLNAHRTRTQLLDAVANLPYKGGNTLTGLALNYILQNNFKPNVGMRPNSRKIGVLVTDGKSQDDIVANSQNLRDQGIELYAIGVKNADENELRTIASDPDDIHMYNVADFSFLLDIVDDLTNNLCNSVKGPGGGPEPPTDLTTSEVTHYSFRATWVAPDGPVEKYRVEYVSTAGGEPQQQMFVDGTVTTVVLEGLTPLTEYIVKVYSVVGEDSSDPLRGIETTLPLSAVRSMNIYKERSTTMNVRWDAATGATGYMLLYKALNATEPSVEQEMRVKGMVTDVQLKKLLPNTAYSVSLFALHGDYASEPLIDQGVTLPLPPSGELRITDVTHSTMQLDWDAAPGAVRKYIITYKPEEGEAKELEVDGDVTSRGLDNLISQTEYDVAVTPVYDSGTGNPMLNQAITDVVPAPQNLRFSMVTQTSFRVHWEHGAPDVSLYRIGWKKKGTTEFQNDILSSEDTTYDLVDLEPDTPYDVSVTAIYPDESESEDLLGTERTLAKLATPPPSGPPQNLQVFDETTTSLTTKWDHAPGRVQNYKITYVPLTGGRSQSTQVGGKKNTVILQKLTPDTPYSITVAAVYASGEARDISGQGKTLPLGSVRNLQVTDPTVSTLNVRWEPAEGSVRQYRIYYQPVAGGAEDMVQVPGSTTSTVLKNLQSDTQYRVTVVPVYAPGEGKRMSETGKTLVRTPAKNIQVYNPTTNTLNVRWEPASGQVQQYRVAYAPLSGIRPSQSVLVPGNTHTALLQQLESDTDYSVSVVALYADGEGSSVSDNGKTLPRSGPRNLRVYDPTTSTLSVGWEHAEGPVIQYRIGYAPTTGDPIEEFTTVPGNRNSVILQNLQPDTPYNINVEAIYQDGPGGRLSGDGKTLDLLGPRNLRVSDEWYTRFRVSWDPAAARVNGYKLVYTPVGTTDTMEAFVGDVTSHHLNNLQPGTTYDLKVYAQYDAGLSGALVGQGTTLYLNVTDLTSYNVGYDSFCIRWTPHRAATSYRLKVNPFNPSHRGAQEVTITAAESQYCFDGLTPDALYNATVYTQTPNREGPGVSVKERTLVKPTVAPTLPPTPPPPATIPSALEVCKGAKADLVFLIDGSWSIGDDSFAKVRQFVFSMIGAFDVVSHEGMQVSFVQYSDDAKTEFKLNTYHDKGMVLSALQMVNYRGGNTKTGAALKHVGEKVFTSDNGMRRTVPKVLVVVTDGRSQDDVKKSAAKLQHAGYSVFVVGVADIDVNELRNIGSKPSDRHVFIVDNFDAFAKIQDNLITFICETATSTCPLIYLNGFTSPGFRMLEAFNITDKTYAGMNGVSLETGSFNSFIAYRLHKDAFISQPTKEIHPDGLPPSYTLILLFRLLPDTGKDAFDLWQISDKNNNPEVGLTIDPSSRVISFYNKDTRGEIQKVSFDNDHVKKIFHGSFHKLHISISPKNVKLNIDCQEVAEKQIKAANNVSTDGYEVLGKMTKSGGSKKQSATFQLQMFDIVCSLGWTSRDKCCDIPAMRDEAKCPALPHSCTCAQDSVGPPGPAGPQGSPGTKGPRGERGESGPTGPMGPRGEQGLPGQMGPPGPQGPNGLSLPGEPGRPGPKGDPGDSGLPGQRGPVGAAGPLGPVGPAGARGPPGSEGPSGPRGPSGPMGPPGAPGMPGITGKPGKPGDTGFPGPVGMKGEKGERGDTASQNMMRSVARQVCEQLVSRQMSRIDMMMNQIPSNYRSNSPGPAGPPGPPGNQGPHGEPGQPGPNGFPGNPGLPGSPGERGVPGEKGERGSPGIGTRGQRGLPGPPGPPGQSQTGPPGPSGSPGPRGPPGQHGSSGVTGPPGPPGYCDSSQCGMPYNGQGYPAGPYQPGSETYVVPIPAAPSEDIETQSPGLRYQRGKRSLSRKEAERIKT", "length": 3113 }, "evidence": [ { "id": "HGNC:2188", "url": "https://alliancegenome.org/gene/HGNC:2188#orthology", "database": "AGR" }, { "id": "RGD:2374", "url": "https://alliancegenome.org/gene/RGD:2374#orthology", "database": "AGR" }, { "id": "MGI:88448", "url": "https://alliancegenome.org/gene/MGI:88448#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090728-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090728-1#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1N401-1", "protein_name": "Collagen alpha-1(XII) chain", "gene_name": "COL12A1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRIRLPPALAALGAALLLSSIEAEVEPPSDLNFKIIDENTVHMSWAIPPDPIVGFKITVDPTTDGPTKEFTLSASTTETLLTELIPEIEYVVTITSYDEVEESVPVIGQLTIQTGGPTKPGEKKPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYYQQEELLAAIKKIPYKGGNTMTGEAIDYLIKNTFTESAGARVGFPKVAIIITDGKSQDEVEIPARELRNIGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVVEPPSNLIATEVSSKYVKLSWSPSPSAVTGYKVLLIPMTTGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGLTSSEPVSIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKDINFSEVTSNSLKTSWSPAGENVFSYHITYKEATGDDQVTLVEPASSTSVVLSNLKPETLYLVNVTAEYEDGFSIPLAGEETTAEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRITYRPVAGGESKEVTTPANQRRRTLENLTPDTKYEVSVIPEYVSGPGSPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWTRAPGKVKQYLITYTPVAGGDTQEVTVKGDTASTVLRGLNEGTQYALSVTALYASGAGDALFGEGTTLEERGSPGDLITKDITDTSIGAYWTSAPGMVRGYRVSWQSLYDDIETGEKSLPADVIHTVIENLQPETKYRVSIFATYSSGEGEPLSGEAMTELSEDSKTLKVDEETENTMRVTWKPAPGKVVNYRVMYRPRGGGRQMVAKVSPTVTSTVLKRLQPQTTYDITVLPVYKTGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFEIGPKRVQIALAQYSGDPRTEWQLNAHKDKKSLLQAVANLPYKGGNTLTGMALNFIRQQSFKTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDIHAYNVADFDSLSRIVDDLTNNLCNSVKGPGDLEAPSNLVLSERTHRSMRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRLERSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDIGSTTMHVQWQPVGGATGYTVTYEPINATVPTKPKEMRLEPTVNDVQLSDLFPNTEYAVTVQAVLHDLTSEPVTAREVTLPLPSPRDLKLRDVTHSTMNVAWEPAPGKVRKYIVRYKTPEEEAKEVEVDRSRASTPLKDLFSQTLYTVSVSAVYEEGESPPVTAQETTHTVPAPTNLQITEVTPESFRGTWDHGASDVSLYRITWAPSGSADKMETILNGDENTLVFQNLNPNTLYEVSVTAIYPDESESDDLIGSERTLRLIPLTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVLLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSSLNVRWDHAEGSPRQYKLFYAPTAGGPEELVPIPGNTNYAILRNLQPDTQYTVTVVPVYSEGDGGRTSDTGRTLVRGLARNVQVYNPTPNSLDVRWDSAPGPVQQYRIVYSPQDGTRPSESIVVPGNTYTVHLEQLIPDTPYSVNIVALYSDAEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIPVYEDGDGTHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEVFVGEVTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQVGWDTFCVRWLAHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTDLSPETDYGVTVFVQTPNLEGPGVSVKERTTLKPTEAPTEPPTPPPPPTIPPAREVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFHTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSSYRLQKNAFVNQPTVELHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTDEVKALFYGSFHKVHIVVTSKSVKIYIDCYEIVEKDIKEAGNITTDGYEILGKLLKGERKSATFQIQNFDIVCSPVWTSRDRCCDIPSRRDEAKCPALPNACTCTQDSVGPPGPPGPAGGPGAKGPRGERGVSGAVGPPGPRGDTGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYHSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPQGERGLPGEKGERGIGSPGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGSG", "length": 3065 }, "evidence": [ { "id": "Q99715", "url": "https://omabrowser.org/oma/group/Q99715/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RQI0-1", "protein_name": "Collagen alpha-1(XII) chain", "gene_name": "COL12A1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRTRLPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWARPADPIVGYRITVDPTTDGPTKEFTLAASTTETLLSELIPEVEYVVTITSYDEVEESVPVIGQLTIQTGDSKKKPGEKKPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQFYQRDELLAAIKKIPYKGGNTMTGDAIDFLIKNTFTESAGARVGFPKVAIIITDGKSQDEVEIPARELRNIGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVIEPPSNLIATEVSSKYIKLSWTPSPSPVTGYKVLLTPMTTGSRQHALSVGPQTTMLSVRDLSADTEYQISVSAMKGLTASEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKDLSFSEVTSYSFNTSWSPAGENVFSYHITYKEATEDGEITVVEPASSTSVVLSNLKPETLYLVNVTAEYEDGFSIPLAGQETTAEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVTGGESKEVTTPANQRRRTLENLTPDTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVTDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGDTQEVTVRGDTTNTILRGLKEGTNYALSVTALYASGAGEALFGEGTTLEERGSPQGLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDIEAGEKSLPGDAIYTVIENLQPETKYRVSVFATYSSGEGEPVSGEATTELSEDAKTLKVDEETENTMRVTWKPAPGKVLNYRVVYRPRGGGRQMVAKVPPAVTSTVLKRLQPQTTYDITVLPIYKAGEGKLRQGSGTTASRFKSPRNLRTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDNGRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFEIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQSFKTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRSLRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRLESSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGSTAMRVQWQPVGGATGYALSYEPINATQPATPKEMRVEPTVNDVQLSDLFPNTEYKVTVQASLYDLTSEPVTAREVTLPLPSPRDLKLRDVTHSTMNVLWEPAPGQVRKYVVRYKTPEEDFKEVEVDRSQTSTPLKDLFSQTLYTVSVSAVYDEGESPPVTAQDTTRTVPAPTNLWISEVTPESFRGTWDHGASDVSLYRITWAPSGSTDKMETILNGDENTLVFENLNPNTLYEVSVTAIYPDESESDDLIGSERTLRLIPLTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTVGGRQNSVLLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGSPRQYKLFYAMAGGPEEMVPIPGNTNYAILRNLQPDTPYTITVVPVYSEGDGGRTSDTGRTLVRGVATNIQVYNPTPNSLDVRWDPAPGPVQQYRLVYSPQAGTRPSESIVVPGNTRMVTLERLVPDTPYSVNIVALYADGEGDPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQSDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEVFVGEVTSYTLHNLNPSTTYDVNVYAQYDSGLSAPLADQGTTLYLNVTDLKTYQVGWDTFCVRWSAHRAATSYRLKLSPSDGTRGQEITVRGSETSHCFTGLSPDNDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPAREVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGAFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIQYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAALIIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRLQKNAFVNQPTAELHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTDEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKNIQEAGNITTDGYEILGKLLKGERKSATFQIQNFDIVCSPVWTSRDRCCDIPSRRDEAKCPALPNACTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAVGPPGPRGDMGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDVASHNMMRAVARQVCEQLISGQMSRFNQMLNQIPNDYHSSRNQPGPPGPPGPPGSVGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGIGSPGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASVPYNGQGYPGSG", "length": 3065 }, "evidence": [ { "id": "Q99715", "url": "https://omabrowser.org/oma/group/Q99715/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P70560-1", "protein_name": "Collagen alpha-1(XII) chain", "gene_name": "Col12a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "PGEPGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGTPGSPGVAGPSGKPGKPGDHGRPGQSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMSRFNQMLNQIPNDYHSNRNQPGPPGPPGPPGAAGARGEPGPGGAPGFPGRPGVQGPPGERGLPGEKGERGIGSQGPRGPPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPEPYVPEGGAYLPDREPFIVPVEPERTAEYEDDYGADEPEQQHPDHRRWRRALRPGPGQ", "length": 317 }, "evidence": [ { "id": "HGNC:2188", "url": "https://alliancegenome.org/gene/HGNC:2188#orthology", "database": "AGR" }, { "id": "RGD:2374", "url": "https://alliancegenome.org/gene/RGD:2374#orthology", "database": "AGR" }, { "id": "MGI:88448", "url": "https://alliancegenome.org/gene/MGI:88448#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120215-116", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-116#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090728-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090728-1#orthology", "database": "AGR" }, { "id": "Q99715", "url": "https://omabrowser.org/oma/group/Q99715/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q60847-1", "protein_name": "Collagen alpha-1(XII) chain", "gene_name": "Col12a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQTRLPRALAALGVALLLSSIEAEVDPPSDLNFKIIDENTVHMSWERPVDPIVGYRITVDPTTDGPTKEFTLAASTTETLLSDLIPETQYVVTITSYNEVEESVPVIGQLTIQTGGPTKPGEKKPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIVALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYYRREDLLAAVKKIPYKGGNTMTGDAIDYLVKNTFTESAGSRAGFPKVAIIITDGKSQDEVEIPARELRNIGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVIEPPSNLVVTELSSKYIRLSWDPSPSAVTGYKILLTPMAAGSRHHALSVGPQTTTLNVRDLTADTEYQISVFAMKGLTSSEPTSVMEKTQPMKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLAKSFEISPNRVQISLVQYSRDPHTEFTLKEFNRVEDIIKAINTFPYRGGSTNTGKAMTYVREKIFVPNKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKDLRFTQVTANSFKAEWSPPGDNVFSYHVTYKDANGDDEVTVVEPASSTSVVLNNLRPETLYLVNVTAEYEDGFSVPITGEETTAEVKGVPRNLKVTDETTDSFKLTWSQAPGRVLRYRIRYRPVSGGESKEVSTPANQRRKTLENLTPDTKYEISVIAEYSSGPGSPLTGNAATEEVRGNPRDLRVSDATTSTLKLSWSRAPGKVKQYLVTYTPAAGGETQEVTVRGDTTTTMLRKLKEGTQYDLSVTALYASGAGEALSGKGSTLEERGSPQNLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDIEAGETTLPGDAIHTMIENLQPETKYKISVFATYSSGEGEPVTGDATTELSQDSKILRVDEETEHTMRVTWKAAPGKVVNYRVVYRPQGGGRQMVAKVPPTVTSTVLKRLQPQTTYDITVLPMYKTGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVLGPYDNTVVLEELRAGTTYRVNVFGMFDGGESLPLVGQEMTTLSDTTVTPFLSSGMDCLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFEIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQSFKTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSKIVDDLTINLCNSVKGPGDLEAPTNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRLDTSTVLKDLKPETDYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGATGYTVSYQPTRSPEGTKPKEMRVGPTVNDVQLTGLLPNTEYEVTVQAVLYDLTSEPAKAREVTLPLPRPQDVKLRDVTHSTMNVVWEPVLGKVRKYIVRYKTPDEEFKEVEVDRSRASTILKDLSSQTQYTVSVSAVYDEGTSPPATAYDTTRRVPAPTNLQFTEVTPESFRGTWDHGASDVSLYRITWAPVGNPDKMETILNGDENTLVFENLNPNTPYEVSITAIYPDESESEDLSGTERTLRLIPLTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTITVGGRQNSVLLQKLKPDTPYTITVYSQYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSSLSVRWDHAEGNPRQYKLFYAPTSGGPEELVPIPGNTNYAILRNLQPDTPYTITVVPVYTEGDGGRTSDTGRTLVRGLARNIQVYNPTPNSLDVRWDPAPGPVQQYRIVYSPVAGTRPSESIVVPGNTRTVHLERLIPDTPYSVNIVALYSDGEGNPSPSQGRTLPRSGPRNIRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAIYEDGDGGHLTGNGRTVGLLPPQNIHIFDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEVTSYTLHNLNPSTTYDVSVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQVGWDTFCVKWSPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPEAEYGVTVFVQTPNLEGPGVPIKEQTTVKPTEAPTEPPTPSPPPTIPPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGAFDEVNPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAAFVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRLQKNAFINQPTAELHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYRPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTDEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNITTDGYEILGKLLKGERKSATFQIQSFDIVCSPVWTSRDRCCDIPSRRDEAKCPALPNACTCTQDSVGPPGPPGPAGGPGAKGPRGERGINGAVGPPGPRGDTGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGQSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMSRFNQMLNQIPNDYHSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERGTGSQGPRGPPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPEPYVPEGGAYLPEREPFIVPVEPERTAEYEDDYGADEPDQQHPDHMRWRRALRPGPAE", "length": 3120 }, "evidence": [ { "id": "HGNC:2188", "url": "https://alliancegenome.org/gene/HGNC:2188#orthology", "database": "AGR" }, { "id": "RGD:2374", "url": "https://alliancegenome.org/gene/RGD:2374#orthology", "database": "AGR" }, { "id": "MGI:88448", "url": "https://alliancegenome.org/gene/MGI:88448#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120215-116", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-116#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090728-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090728-1#orthology", "database": "AGR" }, { "id": "Q99715", "url": "https://omabrowser.org/oma/group/Q99715/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 8, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "Q99715", "url": "https://www.uniprot.org/uniprotkb/Q99715" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "Q99715", "url": "https://www.uniprot.org/uniprotkb/Q99715" } ], "pmid": "" }, { "name": "endoplasmic reticulum lumen", "id": "GO:0005788", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005788", "evidence": [ { "database": "UniProtKB", "id": "Q99715", "url": "https://www.uniprot.org/uniprotkb/Q99715" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "Q99715", "url": "https://www.uniprot.org/uniprotkb/Q99715" } ], "pmid": "" }, { "name": "extracellular exosome", "id": "GO:0070062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070062", "evidence": [ { "database": "UniProtKB", "id": "Q99715", "url": "https://www.uniprot.org/uniprotkb/Q99715" } ], "pmid": "" }, { "name": "extracellular vesicle", "id": "GO:1903561", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903561", "evidence": [ { "database": "UniProtKB", "id": "Q99715", "url": "https://www.uniprot.org/uniprotkb/Q99715" } ], "pmid": "" }, { "name": "collagen type XII trimer", "id": "GO:0005595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005595", "evidence": [ { "database": "UniProtKB", "id": "Q99715", "url": "https://www.uniprot.org/uniprotkb/Q99715" } ], "pmid": "" }, { "name": "interstitial matrix", "id": "GO:0005614", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005614", "evidence": [ { "database": "UniProtKB", "id": "Q99715", "url": "https://www.uniprot.org/uniprotkb/Q99715" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "Q99715", "url": "https://www.uniprot.org/uniprotkb/Q99715" } ], "pmid": "" }, { "name": "collagen fibril organization", "id": "GO:0030199", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030199", "evidence": [ { "database": "UniProtKB", "id": "Q99715", "url": "https://www.uniprot.org/uniprotkb/Q99715" } ], "pmid": "" }, { "name": "endodermal cell differentiation", "id": "GO:0035987", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035987", "evidence": [ { "database": "UniProtKB", "id": "Q99715", "url": "https://www.uniprot.org/uniprotkb/Q99715" } ], "pmid": "" }, { "name": "tissue development", "id": "GO:0009888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009888", "evidence": [ { "database": "UniProtKB", "id": "Q99715", "url": "https://www.uniprot.org/uniprotkb/Q99715" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "extracellular matrix structural constituent conferring tensile strength", "id": "GO:0030020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030020", "evidence": [ { "database": "UniProtKB", "id": "Q99715", "url": "https://www.uniprot.org/uniprotkb/Q99715" } ], "pmid": "" } ] } ] }, "pro_annotation": [ { "name": "collagen alpha-1(XII) chain N-glycosylated 1 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been N-glycosylated at the residue equivalent to Asn-2528 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G09197ZW. Example: UniProtKB:Q99715-1, Asn-2528, MOD:00160~GNO:G09197ZW. [PRO:DNx, PMID:29741879]", "evidence": [ { "id": "PR:000057940", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057940" } ] }, { "name": "collagen alpha-1(XII) chain N-glycosylated 2 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been N-glycosylated at the residue equivalent to Asn-2528 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G11009FR. Example: UniProtKB:Q99715-1, Asn-2528, MOD:00160~GNO:G11009FR. [PRO:DNx, PMID:29741879]", "evidence": [ { "id": "PR:000057941", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057941" } ] }, { "name": "collagen alpha-1(XII) chain N-glycosylated 3 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been N-glycosylated at the residue equivalent to Asn-2528 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G25079LO. Example: UniProtKB:Q99715-1, Asn-2528, MOD:00160~GNO:G25079LO. [PRO:DNx, PMID:29741879]", "evidence": [ { "id": "PR:000057942", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057942" } ] }, { "name": "collagen alpha-1(XII) chain N-glycosylated 4 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been N-glycosylated at the residue equivalent to Asn-2528 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G27622TD. Example: UniProtKB:Q99715-1, Asn-2528, MOD:00160~GNO:G27622TD. [PRO:DNx, PMID:29741879]", "evidence": [ { "id": "PR:000057943", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057943" } ] }, { "name": "collagen alpha-1(XII) chain N-glycosylated 5 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been N-glycosylated at the residue equivalent to Asn-2528 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G37399XV. Example: UniProtKB:Q99715-1, Asn-2528, MOD:00160~GNO:G37399XV. [PRO:DNx, PMID:29741879]", "evidence": [ { "id": "PR:000057944", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057944" } ] }, { "name": "collagen alpha-1(XII) chain N-glycosylated 6 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been N-glycosylated at the residue equivalent to Asn-2528 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G50073PQ. Example: UniProtKB:Q99715-1, Asn-2528, MOD:00160~GNO:G50073PQ. [PRO:DNx, PMID:29741879]", "evidence": [ { "id": "PR:000057945", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057945" } ] }, { "name": "collagen alpha-1(XII) chain N-glycosylated 7 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been N-glycosylated at the residue equivalent to Asn-2528 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G59626AS. Example: UniProtKB:Q99715-1, Asn-2528, MOD:00160~GNO:G59626AS. [PRO:DNx, PMID:29741879]", "evidence": [ { "id": "PR:000057946", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057946" } ] }, { "name": "collagen alpha-1(XII) chain N-glycosylated 8 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been N-glycosylated at the residue equivalent to Asn-2528 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G60923RB. Example: UniProtKB:Q99715-1, Asn-2528, MOD:00160~GNO:G60923RB. [PRO:DNx, PMID:29741879]", "evidence": [ { "id": "PR:000057947", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057947" } ] }, { "name": "collagen alpha-1(XII) chain N-glycosylated 9 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been N-glycosylated at the residue equivalent to Asn-2679 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G09197ZW. Example: UniProtKB:Q99715-1, Asn-2679, MOD:00160~GNO:G09197ZW. [PRO:DNx, PMID:29741879]", "evidence": [ { "id": "PR:000057948", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057948" } ] }, { "name": "collagen alpha-1(XII) chain N-glycosylated 10 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been N-glycosylated at the residue equivalent to Asn-2679 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G11009FR. Example: UniProtKB:Q99715-1, Asn-2679, MOD:00160~GNO:G11009FR. [PRO:DNx, PMID:29741879]", "evidence": [ { "id": "PR:000057949", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057949" } ] }, { "name": "collagen alpha-1(XII) chain N-glycosylated 11 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been N-glycosylated at the residue equivalent to Asn-2679 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G16175ZV. Example: UniProtKB:Q99715-1, Asn-2679, MOD:00160~GNO:G16175ZV. [PRO:DNx, PMID:29741879]", "evidence": [ { "id": "PR:000057950", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057950" } ] }, { "name": "collagen alpha-1(XII) chain N-glycosylated 12 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been N-glycosylated at the residue equivalent to Asn-2679 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G22018FP. Example: UniProtKB:Q99715-1, Asn-2679, MOD:00160~GNO:G22018FP. [PRO:DNx, PMID:29741879]", "evidence": [ { "id": "PR:000057951", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057951" } ] }, { "name": "collagen alpha-1(XII) chain N-glycosylated 13 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been N-glycosylated at the residue equivalent to Asn-2679 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G25079LO. Example: UniProtKB:Q99715-1, Asn-2679, MOD:00160~GNO:G25079LO. [PRO:DNx, PMID:29741879]", "evidence": [ { "id": "PR:000057952", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057952" } ] }, { "name": "collagen alpha-1(XII) chain N-glycosylated 14 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been N-glycosylated at the residue equivalent to Asn-2679 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G27126ED. Example: UniProtKB:Q99715-1, Asn-2679, MOD:00160~GNO:G27126ED. [PRO:DNx, PMID:29741879]", "evidence": [ { "id": "PR:000057953", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057953" } ] }, { "name": "collagen alpha-1(XII) chain N-glycosylated 15 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been N-glycosylated at the residue equivalent to Asn-2679 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G40664HB. Example: UniProtKB:Q99715-1, Asn-2679, MOD:00160~GNO:G40664HB. [PRO:DNx, PMID:29741879]", "evidence": [ { "id": "PR:000057954", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057954" } ] }, { "name": "collagen alpha-1(XII) chain N-glycosylated 16 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been N-glycosylated at the residue equivalent to Asn-2679 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G50073PQ. Example: UniProtKB:Q99715-1, Asn-2679, MOD:00160~GNO:G50073PQ. [PRO:DNx, PMID:29741879]", "evidence": [ { "id": "PR:000057955", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057955" } ] }, { "name": "collagen alpha-1(XII) chain N-glycosylated 17 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been N-glycosylated at the residue equivalent to Asn-2679 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G54600FO. Example: UniProtKB:Q99715-1, Asn-2679, MOD:00160~GNO:G54600FO. [PRO:DNx, PMID:29741879]", "evidence": [ { "id": "PR:000057956", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057956" } ] }, { "name": "collagen alpha-1(XII) chain N-glycosylated 18 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been N-glycosylated at the residue equivalent to Asn-2679 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G58802FE. Example: UniProtKB:Q99715-1, Asn-2679, MOD:00160~GNO:G58802FE. [PRO:DNx, PMID:29741879]", "evidence": [ { "id": "PR:000057957", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057957" } ] }, { "name": "collagen alpha-1(XII) chain N-glycosylated 19 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been N-glycosylated at the residue equivalent to Asn-2679 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G59626AS. Example: UniProtKB:Q99715-1, Asn-2679, MOD:00160~GNO:G59626AS. [PRO:DNx, PMID:29741879]", "evidence": [ { "id": "PR:000057958", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057958" } ] }, { "name": "collagen alpha-1(XII) chain N-glycosylated 20 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been N-glycosylated at the residue equivalent to Asn-2679 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G60923RB. Example: UniProtKB:Q99715-1, Asn-2679, MOD:00160~GNO:G60923RB. [PRO:DNx, PMID:29741879]", "evidence": [ { "id": "PR:000057959", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057959" } ] }, { "name": "collagen alpha-1(XII) chain N-glycosylated 21 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been N-glycosylated at the residue equivalent to Asn-2679 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G62595EF. Example: UniProtKB:Q99715-1, Asn-2679, MOD:00160~GNO:G62595EF. [PRO:DNx, PMID:29741879]", "evidence": [ { "id": "PR:000057960", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057960" } ] }, { "name": "collagen alpha-1(XII) chain N-glycosylated 22 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been N-glycosylated at the residue equivalent to Asn-2679 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G85740DB. Example: UniProtKB:Q99715-1, Asn-2679, MOD:00160~GNO:G85740DB. [PRO:DNx, PMID:29741879]", "evidence": [ { "id": "PR:000057961", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057961" } ] }, { "name": "collagen alpha-1(XII) chain N-glycosylated 23 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been N-glycosylated at the residue equivalent to Asn-2679 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G87051GH. Example: UniProtKB:Q99715-1, Asn-2679, MOD:00160~GNO:G87051GH. [PRO:DNx, PMID:29741879]", "evidence": [ { "id": "PR:000057962", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057962" } ] }, { "name": "collagen alpha-1(XII) chain O-glycosylated 1 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been O-glycosylated at the residue equivalent to Thr-1180 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:Q99715-1, Thr-1180, MOD:00005~GNO:G53434XO. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000057963", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057963" } ] }, { "name": "collagen alpha-1(XII) chain O-glycosylated 2 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been O-glycosylated at the residue equivalent to Thr-1181 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:Q99715-1, Thr-1181, MOD:00005~GNO:G29068FM. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000057964", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057964" } ] }, { "name": "collagen alpha-1(XII) chain O-glycosylated 3 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been O-glycosylated at the residue equivalent to Thr-1181 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q99715-1, Thr-1181, MOD:00005~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000057965", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057965" } ] }, { "name": "collagen alpha-1(XII) chain O-glycosylated 4 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been O-glycosylated at the residue equivalent to Thr-2295 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G30190ML. Example: UniProtKB:Q99715-1, Thr-2295, MOD:00005~GNO:G30190ML. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000057966", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057966" } ] }, { "name": "collagen alpha-1(XII) chain O-glycosylated 5 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been O-glycosylated at the residue equivalent to Thr-2299 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q99715-1, Thr-2299, MOD:00005~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000057967", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057967" } ] }, { "name": "collagen alpha-1(XII) chain O-glycosylated 6 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been O-glycosylated at the residue equivalent to Thr-2299 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:Q99715-1, Thr-2299, MOD:00005~GNO:G53434XO. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000057968", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057968" } ] }, { "name": "collagen alpha-1(XII) chain O-glycosylated 7 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been O-glycosylated at the residue equivalent to Thr-2299 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G57317CE. Example: UniProtKB:Q99715-1, Thr-2299, MOD:00005~GNO:G57317CE. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000057969", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057969" } ] }, { "name": "collagen alpha-1(XII) chain O-glycosylated 8 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been O-glycosylated at the residue equivalent to Thr-2299 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:Q99715-1, Thr-2299, MOD:00005~GNO:G58001LT. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000057970", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057970" } ] }, { "name": "collagen alpha-1(XII) chain O-glycosylated 9 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been O-glycosylated at the residue equivalent to Thr-2299 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G73004SD. Example: UniProtKB:Q99715-1, Thr-2299, MOD:00005~GNO:G73004SD. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000057971", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057971" } ] }, { "name": "collagen alpha-1(XII) chain O-glycosylated 10 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been O-glycosylated at the residue equivalent to Thr-2299 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G88713AC. Example: UniProtKB:Q99715-1, Thr-2299, MOD:00005~GNO:G88713AC. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000057972", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057972" } ] }, { "name": "collagen alpha-1(XII) chain O-glycosylated 11 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been O-glycosylated at the residue equivalent to Thr-2303 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q99715-1, Thr-2303, MOD:00005~GNO:G43417UB. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000057973", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057973" } ] }, { "name": "collagen alpha-1(XII) chain O-glycosylated 12 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been O-glycosylated at the residue equivalent to Thr-2303 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G53434XO. Example: UniProtKB:Q99715-1, Thr-2303, MOD:00005~GNO:G53434XO. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000057974", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057974" } ] }, { "name": "collagen alpha-1(XII) chain O-glycosylated 13 (human)", "definition": "A collagen alpha-1(XII) chain (human) that has been O-glycosylated at the residue equivalent to Thr-2303 of the amino acid sequence represented by UniProtKB:Q99715-1, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:Q99715-1, Thr-2303, MOD:00005~GNO:G58001LT. [PRO:DNx, PMID:30459171]", "evidence": [ { "id": "PR:000057975", "database": "PRO", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:000057975" } ] } ], "site_annotation": [ { "start_pos": 1763, "end_pos": 1765, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2206, "end_pos": 2208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2528, "end_pos": 2530, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2679, "end_pos": 2681, "annotation": "n_glycosylation_sequon" }, { "start_pos": 651, "end_pos": 653, "annotation": "n_glycosylation_sequon" }, { "start_pos": 700, "end_pos": 702, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q99715", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q99715" } ], "ann_type": "Motif_Annotation", "uniprotkb_annotation": "Cell attachment site", "eco_id": "ECO_0000255", "start_pos": 862, "end_pos": 864, "start_aa": "Arg", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "D6RGG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/D6RGG3" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 117, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q99715", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q99715" }, { "id": "PRU00316", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00316" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III 1", "eco_id": "ECO_0000255", "start_pos": 27, "end_pos": 117, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q99715", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q99715" }, { "id": "PRU00316", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00316" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III 10", "eco_id": "ECO_0000255", "start_pos": 1477, "end_pos": 1567, "start_aa": "Val", "end_aa": "Pro", "glycosite_overlap": "Thr1489" }, { "evidence": [ { "id": "Q99715", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q99715" }, { "id": "PRU00316", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00316" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III 11", "eco_id": "ECO_0000255", "start_pos": 1568, "end_pos": 1658, "start_aa": "Arg", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q99715", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q99715" }, { "id": "PRU00316", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00316" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III 12", "eco_id": "ECO_0000255", "start_pos": 1659, "end_pos": 1754, "start_aa": "Thr", "end_aa": "Ser", "glycosite_overlap": "Thr1748,Thr1749,Thr1743" }, { "evidence": [ { "id": "Q99715", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q99715" }, { "id": "PRU00316", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00316" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III 13", "eco_id": "ECO_0000255", "start_pos": 1755, "end_pos": 1849, "start_aa": "Gly", "end_aa": "Asn", "glycosite_overlap": "Asn1763" }, { "evidence": [ { "id": "Q99715", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q99715" }, { "id": "PRU00316", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00316" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin 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