[ { "uniprot_canonical_ac": "Q8TDW7-3", "uniprot_ac": "Q8TDW7", "uniprot_id": "FAT3_HUMAN", "mass": { "chemical_mass": 501978.0, "monoisotopic_mass": 501978.0 }, "refseq": { "ac": "NP_001008781", "name": "protocadherin Fat 3 isoform 2 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008781" }, "gene_names": [ { "name": "FAT3", "type": "recommended", "evidence": [ { "id": "Q8TDW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8TDW7" } ] }, { "name": "CDHF15", "type": "synonym", "evidence": [ { "id": "NP_001008781", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008781" }, { "id": "Q8TDW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8TDW7" } ] }, { "name": "CDHR10", "type": "synonym", "evidence": [ { "id": "NP_001008781", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008781" } ] }, { "name": "FAT3", "type": "synonym", "evidence": [ { "id": "NP_001008781", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008781" } ] }, { "name": "KIAA1989", "type": "synonym", "evidence": [ { "id": "Q8TDW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8TDW7" } ] }, { "name": "hFat3", "type": "synonym", "evidence": [ { "id": "NP_001008781", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008781" } ] } ], "protein_names": [ { "name": "Protocadherin Fat 3", "type": "recommended", "evidence": [ { "id": "Q8TDW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8TDW7/entry#names_and_taxonomy" } ] }, { "name": "Cadherin family member 15", "type": "synonym", "evidence": [ { "id": "Q8TDW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8TDW7/entry#names_and_taxonomy" } ] }, { "name": "FAT tumor suppressor homolog 3", "type": "synonym", "evidence": [ { "id": "NP_001008781", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008781" }, { "id": "Q8TDW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8TDW7/entry#names_and_taxonomy" } ] }, { "name": "cadherin family member 15", "type": "synonym", "evidence": [ { "id": "NP_001008781", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008781" } ] }, { "name": "cadherin-related family member 10", "type": "synonym", "evidence": [ { "id": "NP_001008781", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008781" } ] }, { "name": "hFat3", "type": "synonym", "evidence": [ { "id": "Q8TDW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8TDW7/entry#names_and_taxonomy" } ] }, { "name": "protocadherin Fat 3 isoform 2 precursor", "type": "synonym", "evidence": [ { "id": "NP_001008781", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008781" } ] }, { "name": "protocadherin Fat 3", "type": "synonym", "evidence": [ { "id": "NP_001008781", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008781" } ] } ], "function": [ { "annotation": "A circular RNA derived from FAT atypical cadherin 3 promotes lung cancer progression via forming a regulatory loop with oncogenic ELAV like RNA binding protein 1.", "evidence": [ { "database": "RefSeq", "id": "NP_001008781", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008781" }, { "database": "PubMed", "id": "34647573", "url": "https://glygen.org/publication/PubMed/34647573" } ] }, { "annotation": "Antitumor immunity and prognosis value elicited by FAT3 and LRP1B co-mutation in endometrial cancer.", "evidence": [ { "database": "RefSeq", "id": "NP_001008781", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008781" }, { "database": "PubMed", "id": "38696842", "url": "https://glygen.org/publication/PubMed/38696842" } ] }, { "annotation": "Co-Mutation of FAT3 and LRP1B in Lung Adenocarcinoma Defines a Unique Subset Correlated With the Efficacy of Immunotherapy. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001008781", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008781" }, { "database": "PubMed", "id": "35069585", "url": "https://glygen.org/publication/PubMed/35069585" } ] }, { "annotation": "Fat3 acts through independent cytoskeletal effectors to coordinate asymmetric cell behaviors during polarized circuit assembly.", "evidence": [ { "database": "RefSeq", "id": "NP_001008781", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008781" }, { "database": "PubMed", "id": "35108541", "url": "https://glygen.org/publication/PubMed/35108541" } ] }, { "annotation": "For Fat3, the Kif5-ID is regulated by alternative splicing, and the timecourse of splicing suggests that the distribution of Fat3 may switch between early and later stages of retinal development. In contrast, P75NTR binding to Kif5B is enhanced by tyrosine phosphorylation and thus has the potential to be dynamically regulated on a more rapid time scale Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001008781", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008781" }, { "database": "PubMed", "id": "27788242", "url": "https://glygen.org/publication/PubMed/27788242" } ] }, { "annotation": "Identification of FAT3 as a new candidate gene for adolescent idiopathic scoliosis. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001008781", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008781" }, { "database": "PubMed", "id": "35853984", "url": "https://glygen.org/publication/PubMed/35853984" } ] }, { "annotation": "May play a role in the interactions between neurites derived from specific subsets of neurons during development.", "evidence": [ { "database": "UniProtKB", "id": "Q8TDW7", "url": "https://www.uniprot.org/uniprotkb/Q8TDW7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [ { "tissue": { "name": "Adult mammalian kidney", "namespace": "UBERON", "id": "0000082", "url": "http://purl.obolibrary.org/obo/UBERON_0000082" }, "score": "52.65", "present": "LOW", "evidence": [ { "database": "Bgee", "id": "ENSG00000165323", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000165323" } ] }, { "tissue": { "name": "Oral cavity", "namespace": "UBERON", "id": "0000167", "url": "http://purl.obolibrary.org/obo/UBERON_0000167" }, "score": "41.27", "present": "LOW", "evidence": [ { "database": "Bgee", "id": "ENSG00000165323", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000165323" } ] }, { "tissue": { "name": "Stomach", "namespace": "UBERON", "id": "0000945", "url": "http://purl.obolibrary.org/obo/UBERON_0000945" }, "score": "84.63", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000165323", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000165323" } ] }, { "tissue": { "name": "Esophagus", "namespace": "UBERON", "id": "0001043", "url": "http://purl.obolibrary.org/obo/UBERON_0001043" }, "score": "82.15", "present": "HIGH", "evidence": [ { "database": "Bgee", "id": "ENSG00000165323", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000165323" } ] }, { "tissue": { "name": "Rectum", "namespace": "UBERON", "id": "0001052", "url": "http://purl.obolibrary.org/obo/UBERON_0001052" }, "score": "54.33", "present": "LOW", "evidence": [ { "database": "Bgee", "id": "ENSG00000165323", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000165323" } ] }, { "tissue": { "name": "Urinary bladder", "namespace": "UBERON", "id": "0001255", "url": "http://purl.obolibrary.org/obo/UBERON_0001255" }, "score": "77.55", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000165323", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000165323" } ] }, { "tissue": { "name": "Thyroid gland", "namespace": "UBERON", "id": "0002046", "url": "http://purl.obolibrary.org/obo/UBERON_0002046" }, "score": "40.54", "present": "LOW", "evidence": [ { "database": "Bgee", "id": "ENSG00000165323", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000165323" } ] }, { "tissue": { "name": "Liver", "namespace": "UBERON", "id": "0002107", "url": "http://purl.obolibrary.org/obo/UBERON_0002107" }, "score": "57.96", "present": "LOW", "evidence": [ { "database": "Bgee", "id": "ENSG00000165323", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000165323" } ] }, { "tissue": { "name": "Prostate gland", "namespace": "UBERON", "id": "0002367", "url": "http://purl.obolibrary.org/obo/UBERON_0002367" }, "score": "69.63", "present": "MEDIUM", "evidence": [ { "database": "Bgee", "id": "ENSG00000165323", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000165323" } ] }, { "tissue": { "name": "Thoracic mammary gland", "namespace": "UBERON", "id": "0005200", "url": "http://purl.obolibrary.org/obo/UBERON_0005200" }, "score": "51.35", "present": "LOW", "evidence": [ { "database": "Bgee", "id": "ENSG00000165323", "url": "https://bgee.org/?page=gene&gene_id=ENSG00000165323" } ] } ], "expression_disease": [ { "significant": "Yes", "trend": "down", "name": "Prostate cancer [DO disease name]", "url": "https://disease-ontology.org/term/DOID:10283", "evidence": [ { "database": "BioXpress", "id": "Q8TDW7", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/Q8TDW7" } ], "disease": [ { "disease_id": "DOID:10283", "recommended_name": { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate." }, "synonyms": [ { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "NGP - new growth of prostate", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "hereditary prostate cancer", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "malignant tumor of the prostate", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "prostate cancer, familial", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "prostate neoplasm", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "prostatic cancer", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "prostatic neoplasm", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "tumor of the prostate", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, hereditary, X-linked 1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "HPCX1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, hereditary, X-linked 1", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "prostate cancer, hereditary, X-linked 2", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "HPCX2", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "prostate cancer, hereditary, X-linked 2", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the RNASEL gene." }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "RNASEL familial prostate cancer", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "familial prostate cancer caused by mutation in RNASEL", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, type 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "HPC1", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, type 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "HPC8", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, type 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, susceptibility to, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "HPC3", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, type 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "HPC4", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, type 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "HPC5", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, type 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "HPC6", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "HPC7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, type 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "HPC9", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "HPC10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the EHBP1 gene." }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "EHBP1 familial prostate cancer", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "familial prostate cancer caused by mutation in EHBP1", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, type 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "HPC12", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the MSMB gene." }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "MSMB familial prostate cancer", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "familial prostate cancer caused by mutation in MSMB", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, type 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "HPC13", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "HPC11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "HPC14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "HPC15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0700275", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0700275", "name": "prostate cancer, hereditary", "description": "An instance of prostate cancer that is caused by an inherited genomic modification in an individual. Familial prostate cancer (FPC) is a malignant tumor of the prostate with an early onset. FPC is either asymptomatic or causes mictionary symptoms, erectile dysfunction, bone pain, venous compression and infectious or inflammatory syndrome (for the metastatic forms). It is also characterized by familial antecedents." }, { "id": "MIM:601518", "resource": "MIM", "url": "https://www.omim.org/entry/601518", "name": "Prostate cancer, hereditary, 1", "description": "Prostate cancer, hereditary, 1" }, { "id": "MIM:610997", "resource": "MIM", "url": "https://www.omim.org/entry/610997", "name": "Prostate cancer, hereditary, 9", "description": "Prostate cancer, hereditary, 9" }, { "id": "MIM:611868", "resource": "MIM", "url": "https://www.omim.org/entry/611868", "name": "Prostate cancer, hereditary, 12", "description": "Prostate cancer, hereditary, 12" }, { "id": "MIM:611928", "resource": "MIM", "url": "https://www.omim.org/entry/611928", "name": "Prostate cancer, hereditary, 13", "description": "Prostate cancer, hereditary, 13" }, { "id": "MIM:611955", "resource": "MIM", "url": "https://www.omim.org/entry/611955", "name": "Prostate cancer, hereditary, 11", "description": "Prostate cancer, hereditary, 11" }, { "id": "MIM:176807", "resource": "MIM", "url": "https://www.omim.org/entry/176807", "name": "Prostate cancer", "description": "Prostate cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ] } ] }, { "significant": "Yes", "trend": "down", "name": "Stomach cancer [DO disease name]", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "database": "BioXpress", "id": "Q8TDW7", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/Q8TDW7" } ], "disease": [ { "disease_id": "DOID:10534", "recommended_name": { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach." }, "synonyms": [ { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "gastric cancer", "description": "" }, { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "A primary or metastatic malignant neoplasm involving the stomach." }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca lesser curvature - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "GC", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "cancer of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer risk after h. pylori infection", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer, somatic", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumor", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumour", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant stomach neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "stomach cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca body - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "ca greater curvature of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of body of stomach", "description": "" }, { "id": "MIM:613659", "resource": "MIM", "url": "https://www.omim.org/entry/613659", "name": "Gastric cancer", "description": "Gastric cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" }, { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ] } ] }, { "significant": "Yes", "trend": "down", "name": "Urinary bladder cancer [DO disease name]", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "database": "BioXpress", "id": "Q8TDW7", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/Q8TDW7" } ], "disease": [ { "disease_id": "DOID:11054", "recommended_name": { "id": "DOID:11054", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder." }, "synonyms": [ { "id": "DOID:11054", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11054", "name": "bladder cancer", "description": "" }, { "id": "DOID:11054", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11054", "name": "tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder cancer", "description": "A primary or metastatic malignant neoplasm involving the bladder." }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "tumour of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "bladder cancer, somatic", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "cancer of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder tumour", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm, bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm, urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor, urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant 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This region includes the nasal cavity, sinuses, lips, mouth, salivary glands, throat, or larynx." }, "synonyms": [ { "id": "DOID:11934", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11934", "name": "head and neck neoplasm", "description": "" }, { "id": "DOID:11934", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11934", "name": "head and neck tumours", "description": "" }, { "id": "DOID:11934", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11934", "name": "head/neck neoplasm", "description": "" }, { "id": "DOID:11934", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11934", "name": "tumor of head and neck", "description": "" } ], "unlinked_id_list": [ "DOID:1542" ], "evidence": [ { "id": "11934", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11934" } ] } ] }, { "significant": "Yes", "trend": "down", "name": "Lung cancer [DO disease name]", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "database": "BioXpress", "id": "Q8TDW7", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/Q8TDW7" } ], "disease": [ { "disease_id": "DOID:1324", "recommended_name": { "id": "DOID:1324", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung." }, "synonyms": [ { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer", "description": "A malignant neoplasm involving the lung." }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "adenocarcinoma of lung, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": 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}, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung neoplasm", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung tumor", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung tumour", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant neoplasm of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant neoplasm of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumor of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumor of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumour of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumour of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "nonsmall cell lung cancer, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "nonsmall cell lung cancer, somatic", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "nonsmall cell lung cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility 1", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "LNCR1", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility 1", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "lung cancer susceptibility 3", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "LNCR3", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "lung cancer susceptibility 3", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "lung cancer susceptibility 4", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "LNCR4", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "lung cancer susceptibility 4", "description": "" }, { "id": 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"database": "Pfam", "categories": [ "Other", "Protein Classification" ] }, { "id": "PF12661", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12661", "database": "Pfam", "categories": [ "Other", "Protein Classification" ] }, { "id": "PF23592", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23592", "database": "Pfam", "categories": [ "Other", "Protein Classification" ] }, { "id": "Q8TDW7", "url": "https://pharos.nih.gov/targets/Q8TDW7", "database": "PHAROS", "categories": [ "Organism-specific" ] }, { "id": "PR:Q8TDW7", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q8TDW7", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001008781", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008781", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q8TDW7", "url": "https://www.uniprot.org/uniprotkb/Q8TDW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8TDW7-1", "url": "https://www.uniprot.org/uniprotkb/Q8TDW7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8TDW7-2", "url": "https://www.uniprot.org/uniprotkb/Q8TDW7-2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8TDW7-3", "url": "https://www.uniprot.org/uniprotkb/Q8TDW7-3", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDIIMGHCVGTRPPACCLILLLFKLLATVSQGLPGTGPLGFHFTHSIYNATVYENSAARTYVNSQSRMGITLIDLSWDIKYRIVSGDEEGFFKAEEVIIADFCFLRIRTKGGNSAILNREIQDNYLLIVKGSVRGEDLEAWTKVNIQVLDMNDLRPLFSPTTYSVTIAESTPLRTSVAQVTATDADIGSNGEFYYYFKNKVDLFSVHPTSGVISLSGRLNYDEKNRYDLEILAVDRGMKLYGNNGVSSTAKLYVHIERINEHAPTIHVVTHVPFSLEKEPTYAVVTVDDLDDGANGEIESVSIVAGDPLDQFFLAKEGKWLNEYKIKERKQIDWESFPYGYNLTLQAKDKGSPQKCSALKAVYIGNPTRDTVPIRFEKEVYDVSISEFSPPGVVVAIVKLSPEPIDVEYKLSPGEDAVYFKINPRSGLIVTARPLNTVKKEVYKLEVTNKEGDLKAQVTISIEDANDHTPEFQQPLYDAYVNESVPVGTSVLTVSASDKDKGENGYITYSIASLNLLPFVINQFTGVISTTEELDFESSPEIYRFIVRASDWGSPYRHESEVNVTIRIGNVNDNSPLFEKVACQGVISYDFPVGGHITAVSAIDIDELELVKYKIISGNELGFFYLNPDSGVLQLKKSLTNSGIKNGNFALRITATDGENLADPMSINISVLHGKVSSKSFSCRETRVAQKLAEKLLIKAKANGKLNLEDGFLDFYSINRQGPYFDKSFPSDVAVKEDLPVGANILKIKAYDADSGFNGKVLFTISDGNTDSCFNIDMETGQLKVLMPMDREHTDLYLLNITIYDLGNPQKSSWRLLTINVEDANDNSPVFIQDSYSVNILESSGIGTEIIQVEARDKDLGSNGEVTYSVLTDTQQFAINSSTGIVYVADQLDRESKANYSLKIEARDKAESGQQLFSVVTLKVFLDDVNDCSPAFIPSSYSVKVLEDLPVGTVIAWLETHDPDLGLGGQVRYSLVNDYNGRFEIDKASGAIRLSKELDYEKQQFYNLTVRAKDKGRPVSLSSVSFVEVEVVDVNENLHTPYFPDFAVVGSVKENSRIGTSVLQVTARDEDSGRDGEIQYSIRDGSGLGRFSIDDESGVITAADILDRETMGSYWLTVYATDRGVVPLYSTIEVYIEVEDVNDNAPLTSEPIYYPVVMENSPKDVSVIQIQAEDPDSSSNEKLTYRITSGNPQNFFAINIKTGLITTTSRKLDREQQAEHFLEVTVTDGGPSPKQSTIWVVVQVLDENDNKPQFPEKVYQIKLPERDRKKRGEPIYRAFAFDRDEGPNAEISYSIVDGNDDGKFFIDPKTGMVSSRKQFTAGSYDILTIKAVDNGRPQKSSTARLHIEWIKKPPPSPIPLTFDEPFYNFTVMESDRVTEIVGVVSVQPANTPLWFDIVGGNFDSAFDAEKGVGTIVIAKPLDAEQRSIYNMSVEVTDGTNVAVTQVFIKVLDNNDNGPEFSQPNYDVTISEDVLPDTEILQIEATDRDEKHKLSYTVHSSIDSISMRKFRIDPSTGVLYTAERLDHEAQDKHILNIMVRDQEFPYRRNLARVIVNVEDANDHSPYFTNPLYEASVFESAALGSAVLQVTALDKDKGENAELIYTIEAGNTGNMFKIEPVLGIITICKEPDMTTMGQFVLSIKVTDQGSPPMSATAIVRISVTMSDNSHPKFIHKDYQAEVNENVDIGTSVILISAISQSTLIYEVKDGDINGIFTINPYSGVITTQKALDYERTSSYQLIIQATNMAGMASNATVNIQIVDENDNAPVFLFSQYSGSLSEAAPINSIVRSLDNSPLVIRATDADSNRNALLVYQIVESTAKKFFTVDSSTGAIRTIANLDHETIAHFHFHVHVRDSGSPQLTAESPVEVNIEVTDVNDNPPVFTQAVFETILLLPTYVGVEVLKVSATDPDSEVPPELTYSLMEGSLDHFLIDSNSGVLTIKNNNLSKDHYMLIVKVSDGKFYSTSMVTIMVKEAMDSGLHFTQSFYSTSISENNTNITKVAIVNAVGNRLNEPLKYSILNPGNKFKIKSTSGVIQTTGVPFDREEQELYELVVEASRELDHLRVARVVVRVNIEDINDNSPVFVGLPYYAAVQVDAEPGTLIYQVTAIDKDKGPNGEVTYVLQDDYGHFEINPNSGNVILKEAFNSDLSNIEYGVTILAKDGGKPSLSTSVELPITIVNKAMPVFDKPFYTASVNEDIRMNTPILSINATSPEGQGIIYIIIDGDPFKQFNIDFDTGVLKVVSPLDYEVTSAYKLTIRASDALTGARAEVTVDLLVNDVNDNPPIFDQPTYNTTLSEASLIGTPVLQVVSIDADSENNKMVHYQIVQDTYNSTDYFHIDSSSGLILTARMLDHELVQHCTLKVRSIDSGFPSLSSEVLVHIYISDVNDNPPVFNQLIYESYVSELAPRGHFVTCVQASDADSSDFDRLEYSILSGNDRTSFLMDSKSGVITLSNHRKQRMEPLYSLNVSVSDGLFTSTAQVHIRVLGANLYSPAFSQSTYVAEVRENVAAGTKVIHVRATDGDPGTYGQISYAIINDFAKDRFLIDSNGQVITTERLDRENPLEGDVSIFVRALDGGGRTTFCTVRVIVVDENDNAPQFMTVEYRASVRADVGRGHLVTQVQAIDPDDGANSRITYSLYSEASVSVADLLEIDPDNGWMVTKGNFNQLKNTVLSFFVKAVDGGIPVKHSLIPVYIHVLPPETFLPSFTQSQYSFTIAEDTAIGSTVDTLRILPSQNVWFSTVNGERPENNKGGIFVIEQETGTIKLDKRLDRETSPAFHFKVAATIPLDKVDIVFTVDVDIKVLDLNDNKPVFETSSYDTIIMEGMPVGTKLTQVRAIDMDWGANGQVTYSLHSDSQPEKVMEAFNIDSNTGWISTLKDLDHETDPTFTFSVVASDLGEAFSLSSTALVSVRVTDINDNAPVFAQEVYRGNVKESDPPGEVVAVLSTWDRDTSDVNRQVSYHITGGNPRGRFALGLVQSEWKVYVKRPLDREEQDIYFLNITATDGLFVTQAMVEVSVSDVNDNSPVCDQVAYTALLPEDIPSNKIILKVSAKDADIGSNGYIRYSLYGSGNSEFFLDPESGELKTLALLDRERIPVYSLMAKATDGGGRFCQSNIHLILEDVNDNPPVFSSDHYNTCVYENTATKALLTRVQAVDPDIGINRKVVYSLADSAGGVFSIDSSSGIIILEQPLDREQQSSYNISVRATDQSPGQSLSSLTTVTITVLDINDNPPVFERRDYLVTVPEDTSPGTQVLAVFATSKDIGTNAEITYLIRSGNEQGKFKINPKTGGISVSEVLDYELCKRFYLVVEAKDGGTPALSAVATVNINLTDVNDNPPKFSQDVYSAVISEDALVGDSVILLIAEDVDSQPNGQIHFSIVNGDRDNEFTVDPVLGLVKVKKKLDRERVSGYSLLVQAVDSGIPAMSSTATVNIDISDVNDNSPVFTPANYTAVIQENKPVGTSILQLVVTDRDSFHNGPPFSFSILSGNEEEEFVLDPHGILRSAVVFQHTESLEYVLCVQAKDSGKPQQVSHTYIRVRVIEESTHKPTAIPLEIFIVTMEDDFPGGVIGKIHATDQDMYDVLTFALKSEQKSLFKVNSHDGKIIALGGLDSGKYVLNVSVSDGRFQVPIDVVVHVEQLVHEMLQNTVTIRFENVSPEDFVGLHMHGFRRTLRNAVLTQKQDSLRIISIQPVAGTNQLDMLFAVEMHSSEFYKPAYLIQKLSNARRHLENIMRISAILEKNCSGLDCQEQHCEQGLSLDSHALMTYSTARISFVCPRFYRNVRCTCNGGLCPGSNDPCVEKPCPGDMQCVSYEASRRPFLCQCPPGKLGECSGHTSLSFAGNSYIKYRLSENSKEEDFKLALRLRTLQSNGIIMYTRANPCIILKIVDGKLWFQLDCGSGPGILGISGRAVNDGSWHSVFLELNRNFTSLSLDDSYVERRRAPLYFQTLSTESSIYFGALVQADNIRSLTDTRVTQVLSGFQGCLDSVILNNNELPLQNKRSSFAEVVGLTELKLGCVLYPDACKRSPCQHGGSCTGLPSGGYQCTCLSQFTGRNCESEITACFPNPCRNGGSCDPIGNTFICNCKAGLTGVTCEEDINECEREECENGGSCVNVFGSFLCNCTPGYVGQYCGLRPVVVPNIQAGHSYVGKEELIGIAVVLFVIFILVVLFIVFRKKVFRKNYSRNNITLVQDPATAALLNKSNGIPFRNLRGSGDGRNVYQEVGPPQVPVRPMAYTPCFQSDSRSNLDKIVDGLGGEHQEMTTFHPESPRILTARRGVVVCSVAPNLPAVSPCRSDCDSIRKNGWDAGTENKGVDDPGEVTCFAGSNKGSNSEVQSLSSFQSDSGDDNAYHWDTSDWMPGARLSDIEEVPNYENQDGGSAHQGSTRELESDYYLGGYDIDSEYPPPHEEEFLSQDQLPPPLPEDFPDQYEALPPSQPVSLASTLSPDCRRRPQFHPSQYLPPHPFPNETDLVGPPASCEFSTFAVSMNQGTEPTGPADSVSLSLHNSRGTSSSDVSANCGFDDSEVAMSDYESVGELSLASLHIPFVETQHQTQV", "length": 4557, "header": "sp|Q8TDW7-3|FAT3_HUMAN Isoform 3 of Protocadherin Fat 3 OS=Homo sapiens OX=9606 GN=FAT3 PE=1 SV=3 CANONICAL=Q8TDW7-3" }, "isoforms": [ { "isoform_ac": "Q8TDW7-1", "url": "https://www.uniprot.org/uniprotkb/Q8TDW7/entry#Q8TDW7-1", "sequence": { "sequence": "MDIIMGHCVGTRPPACCLILLLFKLLATVSQGLPGTGPLGFHFTHSIYNATVYENSAARTYVNSQSRMGITLIDLSWDIKYRIVSGDEEGFFKAEEVIIADFCFLRIRTKGGNSAILNREIQDNYLLIVKGSVRGEDLEAWTKVNIQVLDMNDLRPLFSPTTYSVTIAESTPLRTSVAQVTATDADIGSNGEFYYYFKNKVDLFSVHPTSGVISLSGRLNYDEKNRYDLEILAVDRGMKLYGNNGVSSTAKLYVHIERINEHAPTIHVVTHVPFSLEKEPTYAVVTVDDLDDGANGEIESVSIVAGDPLDQFFLAKEGKWLNEYKIKERKQIDWESFPYGYNLTLQAKDKGSPQKCSALKAVYIGNPTRDTVPIRFEKEVYDVSISEFSPPGVVVAIVKLSPEPIDVEYKLSPGEDAVYFKINPRSGLIVTARPLNTVKKEVYKLEVTNKEGDLKAQVTISIEDANDHTPEFQQPLYDAYVNESVPVGTSVLTVSASDKDKGENGYITYSIASLNLLPFVINQFTGVISTTEELDFESSPEIYRFIVRASDWGSPYRHESEVNVTIRIGNVNDNSPLFEKVACQGVISYDFPVGGHITAVSAIDIDELELVKYKIISGNELGFFYLNPDSGVLQLKKSLTNSGIKNGNFALRITATDGENLADPMSINISVLHGKVSSKSFSCRETRVAQKLAEKLLIKAKANGKLNLEDGFLDFYSINRQGPYFDKSFPSDVAVKEDLPVGANILKIKAYDADSGFNGKVLFTISDGNTDSCFNIDMETGQLKVLMPMDREHTDLYLLNITIYDLGNPQKSSWRLLTINVEDANDNSPVFIQDSYSVNILESSGIGTEIIQVEARDKDLGSNGEVTYSVLTDTQQFAINSSTGIVYVADQLDRESKANYSLKIEARDKAESGQQLFSVVTLKVFLDDVNDCSPAFIPSSYSVKVLEDLPVGTVIAWLETHDPDLGLGGQVRYSLVNDYNGRFEIDKASGAIRLSKELDYEKQQFYNLTVRAKDKGRPVSLSSVSFVEVEVVDVNENLHTPYFPDFAVVGSVKENSRIGTSVLQVTARDEDSGRDGEIQYSIRDGSGLGRFSIDDESGVITAADILDRETMGSYWLTVYATDRGVVPLYSTIEVYIEVEDVNDNAPLTSEPIYYPVVMENSPKDVSVIQIQAEDPDSSSNEKLTYRITSGNPQNFFAINIKTGLITTTSRKLDREQQAEHFLEVTVTDGGPSPKQSTIWVVVQVLDENDNKPQFPEKVYQIKLPERDRKKRGEPIYRAFAFDRDEGPNAEISYSIVDGNDDGKFFIDPKTGMVSSRKQFTAGSYDILTIKAVDNGRPQKSSTARLHIEWIKKPPPSPIPLTFDEPFYNFTVMESDRVTEIVGVVSVQPANTPLWFDIVGGNFDSAFDAEKGVGTIVIAKPLDAEQRSIYNMSVEVTDGTNVAVTQVFIKVLDNNDNGPEFSQPNYDVTISEDVLPDTEILQIEATDRDEKHKLSYTVHSSIDSISMRKFRIDPSTGVLYTAERLDHEAQDKHILNIMVRDQEFPYRRNLARVIVNVEDANDHSPYFTNPLYEASVFESAALGSAVLQVTALDKDKGENAELIYTIEAGNTGNMFKIEPVLGIITICKEPDMTTMGQFVLSIKVTDQGSPPMSATAIVRISVTMSDNSHPKFIHKDYQAEVNENVDIGTSVILISAISQSTLIYEVKDGDINGIFTINPYSGVITTQKALDYERTSSYQLIIQATNMAGMASNATVNIQIVDENDNAPVFLFSQYSGSLSEAAPINSIVRSLDNSPLVIRATDADSNRNALLVYQIVESTAKKFFTVDSSTGAIRTIANLDHETIAHFHFHVHVRDSGSPQLTAESPVEVNIEVTDVNDNPPVFTQAVFETILLLPTYVGVEVLKVSATDPDSEVPPELTYSLMEGSLDHFLIDSNSGVLTIKNNNLSKDHYMLIVKVSDGKFYSTSMVTIMVKEAMDSGLHFTQSFYSTSISENNTNITKVAIVNAVGNRLNEPLKYSILNPGNKFKIKSTSGVIQTTGVPFDREEQELYELVVEASRELDHLRVARVVVRVNIEDINDNSPVFVGLPYYAAVQVDAEPGTLIYQVTAIDKDKGPNGEVTYVLQDDYGHFEINPNSGNVILKEAFNSDLSNIEYGVTILAKDGGKPSLSTSVELPITIVNKAMPVFDKPFYTASVNEDIRMNTPILSINATSPEGQGIIYIIIDGDPFKQFNIDFDTGVLKVVSPLDYEVTSAYKLTIRASDALTGARAEVTVDLLVNDVNDNPPIFDQPTYNTTLSEASLIGTPVLQVVSIDADSENNKMVHYQIVQDTYNSTDYFHIDSSSGLILTARMLDHELVQHCTLKVRSIDSGFPSLSSEVLVHIYISDVNDNPPVFNQLIYESYVSELAPRGHFVTCVQASDADSSDFDRLEYSILSGNDRTSFLMDSKSGVITLSNHRKQRMEPLYSLNVSVSDGLFTSTAQVHIRVLGANLYSPAFSQSTYVAEVRENVAAGTKVIHVRATDGDPGTYGQISYAIINDFAKDRFLIDSNGQVITTERLDRENPLEGDVSIFVRALDGGGRTTFCTVRVIVVDENDNAPQFMTVEYRASVRADVGRGHLVTQVQAIDPDDGANSRITYSLYSEASVSVADLLEIDPDNGWMVTKGNFNQLKNTVLSFFVKAVDGGIPVKHSLIPVYIHVLPPETFLPSFTQSQYSFTIAEDTAIGSTVDTLRILPSQNVWFSTVNGERPENNKGGIFVIEQETGTIKLDKRLDRETSPAFHFKVAATIPLDKVDIVFTVDVDIKVLDLNDNKPVFETSSYDTIIMEGMPVGTKLTQVRAIDMDWGANGQVTYSLHSDSQPEKVMEAFNIDSNTGWISTLKDLDHETDPTFTFSVVASDLGEAFSLSSTALVSVRVTDINDNAPVFAQEVYRGNVKESDPPGEVVAVLSTWDRDTSDVNRQVSYHITGGNPRGRFALGLVQSEWKVYVKRPLDREEQDIYFLNITATDGLFVTQAMVEVSVSDVNDNSPVCDQVAYTALLPEDIPSNKIILKVSAKDADIGSNGYIRYSLYGSGNSEFFLDPESGELKTLALLDRERIPVYSLMAKATDGGGRFCQSNIHLILEDVNDNPPVFSSDHYNTCVYENTATKALLTRVQAVDPDIGINRKVVYSLADSAGGVFSIDSSSGIIILEQPLDREQQSSYNISVRATDQSPGQSLSSLTTVTITVLDINDNPPVFERRDYLVTVPEDTSPGTQVLAVFATSKDIGTNAEITYLIRSGNEQGKFKINPKTGGISVSEVLDYELCKRFYLVVEAKDGGTPALSAVATVNINLTDVNDNPPKFSQDVYSAVISEDALVGDSVILLIAEDVDSQPNGQIHFSIVNGDRDNEFTVDPVLGLVKVKKKLDRERVSGYSLLVQAVDSGIPAMSSTATVNIDISDVNDNSPVFTPANYTAVIQENKPVGTSILQLVVTDRDSFHNGPPFSFSILSGNEEEEFVLDPHGILRSAVVFQHTESLEYVLCVQAKDSGKPQQVSHTYIRVRVIEESTHKPTAIPLEIFIVTMEDDFPGGVIGKIHATDQDMYDVLTFALKSEQKSLFKVNSHDGKIIALGGLDSGKYVLNVSVSDGRFQVPIDVVVHVEQLVHEMLQNTVTIRFENVSPEDFVGLHMHGFRRTLRNAVLTQKQDSLRIISIQPVAGTNQLDMLFAVEMHSSEFYKPAYLIQKLSNARRHLENIMRISAILEKNCSGLDCQEQHCEQGLSLDSHALMTYSTARISFVCPRFYRNVRCTCNGGLCPGSNDPCVEKPCPGDMQCVSYEASRRPFLCQCPPGKLGECSGHTSLSFAGNSYIKYRLSENSKEEDFKLALRLRTLQSNGIIMYTRANPCIILKIVDGKLWFQLDCGSGPGILGISGRAVNDGSWHSVFLELNRNFTSLSLDDSYVERRRAPLYFQTLSTESSIYFGALVQADNIRSLTDTRVTQVLSGFQGCLDSVILNNNELPLQNKRSSFAEVVGLTELKLGCVLYPDACKRSPCQHGGSCTGLPSGGYQCTCLSQFTGRNCESEITACFPNPCRNGGSCDPIGNTFICNCKAGLTGVTCEEDINECEREECENGGSCVNVFGSFLCNCTPGYVGQYCGLRPVVVPNIQAGHSYVGKEELIGIAVVLFVIFILVVLFIVFRKKVFRKNYSRNNITLVQDPATAALLNKSNGIPFRNLRGSGDGRNVYQEVGPPQVPVRPMAYTPCFQSDSRSNLDKIVDGLGGEHQEMTTFHPESPRILTARRGVVVCSVAPNLPAVSPCRSDCDSIRKNGWDAGTENKGVDDPGEVTCFAGSNKGSNSEVQSLSSFQSDSGDDNASIVTVIQLVNNVVDTIENEVSVMDQGQNYNRAYHWDTSDWMPGARLSDIEEVPNYENQDGGSAHQGSTRELESDYYLGGYDIDSEYPPPHEEEFLSQDQLPPPLPEDFPDQYEALPPSQPVSLASTLSPDCRRRPQFHPSQYLPPHPFPNETDLVGPPASCEFSTFAVSMNQGTEPTGPADSVSLSLHNSRGTSSSDVSANCGFDDSEVAMSDYESVGELSLASLHIPFVETQHQTQV", "length": 4589, "header": "sp|Q8TDW7-1|FAT3_HUMAN Isoform 1 of Protocadherin Fat 3 OS=Homo sapiens OX=9606 GN=FAT3 PE=1 SV=3 CANONICAL=Q8TDW7-3" }, "locus": {} }, { "isoform_ac": "Q8TDW7-2", "url": "https://www.uniprot.org/uniprotkb/Q8TDW7/entry#Q8TDW7-2", "sequence": { "sequence": "MDIIMGHCVGTRPPACCLILLLFKLLATVSQGLPGTGPLGFHFTHSIYNATVYENSAARTYVNSQSRMGITLIDLSWDIKYRIVSGDEEGFFKAEEVIIADFCFLRIRTKGGNSAILNREIQDNYLLIVKGSVRGEDLEAWTKVNIQVLDMNDLRPLFSPTTYSVTIAESTPLRTSVAQVTATDADIGSNGEFYYYFKNKVDLFSVHPTSGVISLSGRLNYDEKNRYDLEILAVDRGMKLYGNNGVSSTAKLYVHIERINEHAPTIHVVTHVPFSLEKEPTYAVVTVDDLDDGANGEIESVSIVAGDPLDQFFLAKEGKWLNEYKIKERKQIDWESFPYGYNLTLQAKDKGSPQKCSALKAVYIGNPTRDTVPIRFEKEVYDVSISEFSPPGVVVAIVKLSPEPIDVEYKLSPGEDAVYFKINPRSGLIVTARPLNTVKKEVYKLEVTNKEGDLKAQVTISIEDANDHTPEFQQPLYDAYVNESVPVGTSVLTVSASDKDKGENGYITYSIASLNLLPFVINQFTGVISTTEELDFESSPEIYRFIVRASDWGSPYRHESEVNVTIRIGNVNDNSPLFEKVACQGVISYDFPVGGHITAVSAIDIDELELVKYKIISGNELGFFYLNPDSGVLQLKKSLTNSGIKNGNFALRITATDGENLADPMSINISVLHGKVSSKSFSCRETRVAQKLAEKLLIKAKANGKLNLEDGFLDFYSINRQGPYFDKSFPSDVAVKEDLPVGANILKIKAYDADSGFNGKVLFTISDGNTDSCFNIDMETGQLKVLMPMDREHTDLYLLNITIYDLGNPQKSSWRLLTINVEDANDNSPVFIQDSYSVNILESSGIGTEIIQVEARDKDLGSNGEVTYSVLTDTQQFAINSSTGIVYVADQLDRESKANYSLKIEARDKAESGQQLFSVVTLKVFLDDVNDCSPAFIPSSYSVKVLEDLPVGTVIAWLETHDPDLGLGGQVRYSLVNDYNGRFEIDKASGAIRLSKELDYEKQQFYNLTVRAKDKGRPVSLSSVSFVEVEVVDVNENLHTPYFPDFAVVGSVKENSRIGTSVLQVTARDEDSGRDGEIQYSIRDGSGLGRFSIDDESGVITAADILDRETMGSYWLTVYATDRGVVPLYSTIEVYIEVEDVNDNAPLTSEPIYYPVVMENSPKDVSVIQIQAEDPDSSSNEKLTYRITSGNPQNFFAINIKTGSCSVAQAGMQWHDRSSLQSRTPGFKGYPCLSLLSSWDYRHAPPCPATFLNS", "length": 1254, "header": "sp|Q8TDW7-2|FAT3_HUMAN Isoform 2 of Protocadherin Fat 3 OS=Homo sapiens OX=9606 GN=FAT3 PE=1 SV=3 CANONICAL=Q8TDW7-3" }, "locus": {} }, { "isoform_ac": "Q8TDW7-3", "url": "https://www.uniprot.org/uniprotkb/Q8TDW7/entry#Q8TDW7-3", "sequence": { "sequence": 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"length": 4557, "header": "sp|Q8TDW7-3|FAT3_HUMAN Isoform 3 of Protocadherin Fat 3 OS=Homo sapiens OX=9606 GN=FAT3 PE=1 SV=3 CANONICAL=Q8TDW7-3" }, "locus": { "chromosome": "11", "start_pos": 92891110, "end_pos": 92352113, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000409404.6", "url": "https://www.ensembl.org/id/ENST00000409404.6" }, { "database": "Ensembl Peptide", "id": "ENSP00000387040.2", "url": "https://www.ensembl.org/id/ENSP00000387040.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "G80920RR", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "QQFYNLTVR", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1007, "start_aa": "Asn", "end_pos": 1007, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1007", "evidence": [ { "id": "10.1101/2023.09.13.557529", "database": "DOI", "url": "https://glygen.org/publication/DOI/10.1101/2023.09.13.557529" }, { "id": "GLY_000888", "database": "Data Submission", "url": "http://data.glygen.org/GLY_000888" } ], "filter_code": "00100000000000000000.0000000.00010000000000.0100000.1100000000.110111110111111110.00010.01000" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1007, "start_aa": "Asn", "end_pos": 1007, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1007", "evidence": [ { "id": "Q8TDW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8TDW7#ptm_processing" }, { "id": "24190977", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/24190977" }, { "id": "GLY_000143", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000143" } ], "filter_code": "00100000000000000000.00010000000000.00.01000" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1368, "start_aa": "Asn", "end_pos": 1368, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1368", "evidence": [ { "id": "Q8TDW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8TDW7#ptm_processing" } ], "filter_code": "00100000000000000000.00010000000000.0.01001" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1430, "start_aa": "Asn", "end_pos": 1430, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1430", "evidence": [ { "id": "Q8TDW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8TDW7#ptm_processing" } ], "filter_code": "00100000000000000000.00010000000000.0.01001" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1752, "start_aa": "Asn", "end_pos": 1752, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1752", "evidence": [ { "id": "Q8TDW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8TDW7#ptm_processing" } ], "filter_code": "00100000000000000000.00010000000000.0.01001" }, { "glytoucan_ac": "G85677PP", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "NNNLSKDHYMLIVK", 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"https://www.uniprot.org/uniprotkb/Q8TDW7#ptm_processing" } ], "filter_code": "00100000000000000000.00010000000000.00.01001" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1994, "start_aa": "Asn", "end_pos": 1994, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn1994", "evidence": [ { "id": "Q8TDW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8TDW7#ptm_processing" } ], "filter_code": "00100000000000000000.00010000000000.0.01001" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 1997, 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immunopeptidome of an acute myeloid leukemia cell line using complementary ligand enrichment and data acquisition strategies.", "journal": "Molecular immunology", "date": "2020-07", "authors": "Pandey Kirti, Mifsud Nicole A, Lim Kam Sian Terry C C, Ayala Rochelle, Ternette Nicola, Ramarathinam Sri H, Purcell Anthony W", "evidence": [ { "database": "IEDB", "id": "658086", "url": "https://www.iedb.org/epitope/658086" }, { "database": "IEDB", "id": "1351335", "url": "https://www.iedb.org/epitope/1351335" }, { "database": "IEDB", "id": "1377143", "url": "https://www.iedb.org/epitope/1377143" } ], "reference": [ { "type": "PubMed", "id": "32387766", "url": "https://glygen.org/publication/PubMed/32387766" } ] }, { "title": "CIITA-Transduced Glioblastoma Cells Uncover a Rich Repertoire of Clinically Relevant Tumor-Associated HLA-II Antigens.", "journal": "Molecular & cellular proteomics : MCP", "date": "2021", "authors": "Forlani Greta, Michaux Justine, Pak HuiSong, Huber Florian, Marie Joseph Elodie Lauret, Ramia Elise, Stevenson Brian J, Linnebacher Michael, Accolla Roberto S, Bassani-Sternberg Michal", "evidence": [ { "database": "IEDB", "id": "1620778", "url": "https://www.iedb.org/epitope/1620778" } ], "reference": [ { "type": "PubMed", "id": "33592498", "url": "https://glygen.org/publication/PubMed/33592498" } ] }, { "title": "NMD inhibition by 5-azacytidine augments presentation of immunogenic frameshift-derived neoepitopes.", "journal": "iScience", "date": "2021-04-23", "authors": "Becker Jonas P, Helm Dominic, Rettel Mandy, Stein Frank, Hernandez-Sanchez Alejandro, Urban Katharina, Gebert Johannes, Kloor Matthias, Neu-Yilik Gabriele, von Knebel Doeberitz Magnus, Hentze Matthias W, Kulozik Andreas E", "evidence": [ { "database": "IEDB", "id": "1713532", "url": "https://www.iedb.org/epitope/1713532" } ], "reference": [ { "type": "PubMed", "id": "33981976", "url": "https://glygen.org/publication/PubMed/33981976" } ] }, { "title": "Profiling SARS-CoV-2 HLA-I peptidome reveals T\u00a0cell epitopes from out-of-frame ORFs.", "journal": "Cell", "date": "2021-07-22", "authors": "Weingarten-Gabbay Shira, Klaeger Susan, Sarkizova Siranush, Pearlman Leah R, Chen Da-Yuan, Gallagher Kathleen M E, Bauer Matthew R, Taylor Hannah B, Dunn W Augustine, Tarr Christina, Sidney John, Rachimi Suzanna, Conway Hasahn L, Katsis Katelin, Wang Yuntong, Leistritz-Edwards Del, Durkin Melissa R, Tomkins-Tinch Christopher H, Finkel Yaara, Nachshon Aharon, Gentili Matteo, Rivera Keith D, Carulli Isabel P, Chea Vipheaviny A, Chandrashekar Abishek, Bozkus Cansu Cimen, Carrington Mary, , Bhardwaj Nina, Barouch Dan H, Sette Alessandro, Maus Marcela V, Rice Charles M, Clauser Karl R, Keskin Derin B, Pregibon Daniel C, Hacohen Nir, Carr Steven A, Abelin Jennifer G, Saeed Mohsan, Sabeti Pardis C", "evidence": [ { "database": "IEDB", "id": "1333866", "url": "https://www.iedb.org/epitope/1333866" } ], "reference": [ { "type": "PubMed", "id": "34171305", "url": "https://glygen.org/publication/PubMed/34171305" } ] }, { "title": "A circular RNA derived from FAT atypical cadherin 3 promotes lung cancer progression via forming a regulatory loop with oncogenic ELAV like RNA binding protein 1.", "journal": "Journal of biochemistry", "date": "2022", "authors": "Jiang H, Tian Y, Zhao X, Zhang L, Wu Z", "evidence": [ { "database": "RefSeq", "id": "NP_001008781", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008781" } ], "reference": [ { "type": "PubMed", "id": "34647573", "url": "https://glygen.org/publication/PubMed/34647573" } ] }, { "title": "Co-Mutation of FAT3 and LRP1B in Lung Adenocarcinoma Defines a Unique Subset Correlated With the Efficacy of Immunotherapy.", "journal": "Frontiers in immunology", "date": "2021", "authors": "Zhu M, Zhang L, Cui H, Zhao Q, Wang H, Zhai B, Jiang R, Jiang Z", "evidence": [ { "database": "RefSeq", "id": "NP_001008781", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008781" } ], "reference": [ { "type": "PubMed", "id": "35069585", "url": "https://glygen.org/publication/PubMed/35069585" } ] }, { "title": "Fat3 acts through independent cytoskeletal effectors to coordinate asymmetric cell behaviors during polarized circuit assembly.", "journal": "Cell reports", "date": "2022", "authors": "Aviles EC, Krol A, Henle SJ, Burroughs-Garcia J, Deans MR, Goodrich LV", "evidence": [ { "database": "RefSeq", "id": "NP_001008781", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008781" } ], "reference": [ { "type": "PubMed", "id": "35108541", "url": "https://glygen.org/publication/PubMed/35108541" } ] }, { "title": "Soluble HLA peptidome of pleural effusions is a valuable source for tumor antigens.", "journal": "Journal for immunotherapy of cancer", "date": "2022-05", "authors": "Khazan-Kost Sofia, Cafri Gal, Melamed Kadosh Dganit, Mooshayef Navit, Chatterji Sumit, Dominissini Dan, Manor Sigal, Zisser Bracha, Broday Limor, Talalai Efrosiniia, Shemer Anat, Zadok Oranit, Ofek Efrat, Onn Amir, Admon Arie, Peled Michael", "evidence": [ { "database": "IEDB", "id": "2261851", "url": "https://www.iedb.org/epitope/2261851" } ], "reference": [ { "type": "PubMed", "id": "35580925", "url": "https://glygen.org/publication/PubMed/35580925" } ] }, { "title": "Identification of FAT3 as a new candidate gene for adolescent idiopathic scoliosis.", "journal": "Scientific reports", "date": "2022", "authors": "Nada D, Julien C, Papillon-Cavanagh S, Majewski J, Elbakry M, Elremaly W, Samuels ME, Moreau A", "evidence": [ { "database": "RefSeq", "id": "NP_001008781", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008781" } ], "reference": [ { "type": "PubMed", "id": "35853984", "url": "https://glygen.org/publication/PubMed/35853984" } ] }, { "title": "Antitumor immunity and prognosis value elicited by FAT3 and LRP1B co-mutation in endometrial cancer.", "journal": "Gynecologic oncology", "date": "2024-08", "authors": "Jiang Zhansheng, Zhu Mingyu, Zhang Lu, Cui Haiyan, Jiang Richeng, Yang Yanfang", "evidence": [ { "database": "RefSeq", "id": "NP_001008781", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001008781" } ], "reference": [ { "type": "PubMed", "id": "38696842", "url": "https://glygen.org/publication/PubMed/38696842" } ] } ], "pathway": [ { "id": "hsa:120114", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?hsa:120114", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A087WRT4-1", "protein_name": "FAT atypical cadherin 1", "gene_name": "Fat1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRHLTLLLLLLLFLQQFGDSDGSQRLEPTPPIQFTHFQYNVTVHENSAAKTYVGHPRKMGIYILDPSWEIRYKIVSGDSENLFKAEEYVLGDFCFLRIRTKGGNTAILNREVRDHYTLIVKAVEKATDAEARAKVRVQVLDTNDLRPLFSPTSYSVSLPENTAIRTSIARVSATDADIGTNGEFYYSFKDRTDVFAIHPTSGVVVLTGRLDFLETQLYELEILAADRGMKLYGSSGVSSLAKLTVHVEQANECAPIITAVTLSPSELDKDPTYAIITVEDCDQGANGEIASLSIVAGDLLQQFKTVRSFPGSKAFKVKAVGAVDWDSHPYGYNLTLQAKDKGTPPQFSPVKVVHIISPQFRAGPVKFEMDVYRAEISEFAPPHTPVVLVKAIPSYSHLRYVFKSAPGKPKFGLNHNTGLISILEPIRRQHTSHFELEVTTSDKRASARVVVKVLGTNSNPPEFTQTSYKASIDENAPIGAAVTRVSAMDPDEGENGYVTYSIANLNHVPFVIDHFTGTVSTSENLDYELMPRVYTLRIRASDWGLPYRREVEVLATITLNNLNDNTPLFERINCEGTIPRDLGVGEQITTVSAIDADELQLVRYQIEAGNELDLFGLNPSSGVLSLKHSLTDGLGAKVSFHSLRITATDGENFATPLYINLTVAASRKPVNLQCEETGVAKMLAEKLLQANKLHSQGDVEDIFFDSYSVNTHTPQFGVTLPTGIEVKENLPVGANILFMNATDLDSGFNGKLVYAISGGNDDSCFTIDMETGVLKVLSPLDREVMDKYTLNITVYDLGIPQRAAWRLLDVTVLDANDNAPEFLQESYFVEVSEDKEVNSEIIQVEATDKDLGPSGHVTYAILTDTEKFSIDSMTGVVKIIQPLDREVQPVHYLKIEARDQATEEPRLFSTVLLKVSLDDVNDNPPRFIPPNYSVKVREDLPEGTIIMWLEAYDPDVGQSSQVRYSLLDHGEGHFDVDKLSGAVRIVQQLDFEKKQLYNLTVRAKDKGKPVSLSSTCYVEVEVVDVNENLHTPVFSSFVEKGVVKEDVPTGSSVMTVSAHDEDTGRDGEIRYSIRDGSGIGVFRIDEETGVIETSDRLDRESTSHYWLTVYATDQGVVPLSSFIEVYIEVEDVNDNAPQTSEPVYYPEIMENSPKDVSVVQIEAFDPDSSSNDKLTYRITSGNPQGFFSIHPKTGLITTTSRKLDREQQDEHILEVTVTDNGVPPRSTIARVIVKILDENDNRPQFLQKFYKIRLPEREKADGDRSASKREPLYRVIAADKDEGPNAELSYSIEEGNEHGRFSIEPKTGVVSSKKFSAAGEYDILSIKAVDNGRPQKSSTTRLHIEWISKPKPSSEPISFEESVFSFTVMESDPVAHMIGVISVEPPGMPLWFDIIGGNYDSHFDVDKGTGTIIVAKPLDAEQKSSYNLTVEATDGTTTILTQVLIKVIDTNDHRPQFSTSKYEVAVPEDTEPEVEILQISAVDRDEKNKLIYTLQSSIDPASLKKFRLDPATGALYTAEKLDHEAIHQHVLTVMVRDQDVPVKRNFARIVVNVSDKNDHAPWFTSPSYDGRVYESAAVGSVVLQVTALDKDKGRNAEVLYSIESGNIGNSFTIDPILGSIKTARELDRSHQVDYDLMVKATDKGDPPMSEMTSVRIAVTVADNASPKFTSKEYSAEISEAIRIGSFVGMVSAHSQSSVMYEIRDGNMGDAFNINPHSGSIITQRALDFETLPMYSLTVQGTNMAGLSTNTTVVVHVRDENDNPPVFTQAEYSGFISESASVNSVVLTDRNVPLVIRATDADRESNALLVYQIVEPSVHNYFAIDPTTGAIRTVLSLDYEETHAFHFTVQVHDMGTPRLFAEYAANVTVHVIDINDCPPVFSKSLYEVSLLLPTYRGVNVITVNATDADSKAFSQVMYSITEGNIGEKFSMDHKTGTIAIQNTTQLRSRYELTVRASDGRFTSMASVKINVKESRESPLKFTQDAYSAVVKENSTEARTLAVITAIGNPLNEPLFYRILNPDRRFKISHTSGVLSTTGIPFDREQQETFDVVVEVTKEHEPSAVAHVVVKVTVEDQNDNAPVFVNLPYYAVVKVDAEVGHVIRYVTAIDRDSGRNGDIHYYLKEHHDHFQIGPSGDISLKKQFEHDTLNKEYLVTVVAKDGGSPAFSAEVLVPITVMNKAMPVFEKAFYSAEIPENIQMHSPVVHIQANSPEGLKVFYSITDGDPFSQFTINFNTGVVNVIAPLDFESHPAYKLSVRATDSLTGAHAEVFVDIIVEDINDNPPVFVQPSYSTTLSEASVIGTPVLQVRATDSDSEPNRGISYQLIGNHSKSHDHFHIDSNTGLISLVRALDYEQSQQHRIFVRAVDGGMPALSSDVVVTVAVTDLNDNPPLFEQQVYEARISEHAAHGHFVMCVRACDADSSDLDKLEYSILSGNDHKSFIIDRETGIITLSNLRRHTLKPFYSLNVSVSDGVFRSSARVNVTVMGGNLHSPVFHQNEYEVELAENAPLHTLVVQVKASDRDSGIYSHVTYHIVNDFAKDRFYVNDRGQIFTLEKLDRETPAEKVISIRLMAKDAGGKVAFCTVNVILTDDNDNAPQFRSTKYEVNIGSSAAKGTSVVKVFASDADEGSNADVTYAIEADSESVKENLEINKLTGLITTKESLIGLENEFFTFFVRAVDSGSPPRESVVPVYIKILPPEVQLPRFSEPFYTYTISEDTPIGTEIDLIRVEHGGAVLYILVKGNTPESNRDEFFVIDRQNGRLKLEKSLDHETTKWYQFSILARCTLDDYEVVASIDVSIQVKDANDNSPVLESSPYEAFIVENLPGGSRVIQIRASDLDSGANGQVMYSLDQSQDADIIESFAINMETGWITTLKELDHEERASYQIKVVASDHGEKVQLSSTAIVGVTVTDVNDSPPRFTAEIYKGTVSEDDPPGGVIAILSTTDADTEEINRQVSYFITGGDALGQFAVENVQSDWRVYVKKPLDREQKDSYLLTVTATDGTFSSKARVEVKVLDANDNSPVCEKTSYSDTIPEDALPGKLVMQVSATDADIRSNAEITYTLFGSGAEKFKLNPDTGELRTLALLDREEQAVYNLLVKATDGGGRSCQAAIVLTLEDVNDNAPEFTAEPYTITVFENTEPGTPLTRVQATDADTGLNRKISYSLVESADGQFSINERSGIIQLEKHLDRELQAVYTLTLKAVDQGLPRRLTATGTVVVSVLDINDNPPVFEYREYGASVSEDIVIGTEVLQVYAASRDIEANAEITYAIISGNEHGKFSIDSKTGAIFIIESLDYESSHEYYLTVEATDGGTPSLSDVATVNINVTDINDNSPVFSQDTYTTVVSEDAALEQPVITIMADDADGPSNSHIHYSIIEGNQGSPFTIDPVRGEVKVTKPLDRETISGYTLTVQAADNGNPPRVNTTTVNIDVSDVNDNAPLFSRDNYSVIIQENKPVGFSVLKLVVTDKDSSHNGPPFFFTIVSGNDENAFEVNQHGVLLTAATIKRKVKDHYLLHVKVADSGKPQLSSMTHIDIRVIEESIHPPAILPLEIFITAFGEEYSGGVIGKIHATDQDVYDTLMYSLDPHMDGLFSVSSTGGKLIAHRKLDIGQYLLNVSVTDGKFTTVADITVHIQQVTQEMLNHTVAIRFANLTPEEFVGDYWRNFQRALRNILGVRKNDIQIVSLQPSEPHSHLDVLLFVERSGGTHVSTKQLLHKINSSVTDVEEIIGVRILEVFQKLCAGLDCPWKFCDEKVSVDENVMSTHSTARLSFVTPRHHRTAVCLCKDGTCPPVHHGCEDNPCPAGSECVADPREEKYSCVCPGGGFGKCPGSSSITFTGNSFVKYRLLENENRLEMKLSMRLRTYSSHAVVMYARGTDYSILEIHTGRLQYKFDCGSGPGIVSVQSIQVNDGQWHAVSLEVEGNYAKLVLDEVHTASGTAPGALKTLNLDNYVFFGGHLRQQGTKHGRGAQVASGFRGCMDSIYLNGQELPLNNKPRAYAHIEEWVDLSHGCLLTATEDCSSSPCQNGGVCNPSPTGGYYCKCSALYVGTFCEVSVNPCSSNPCLYGGTCMVDNGGFVCQCRGLYTGQRCQLSPYCKDDPCKNGGTCFDSLDGAVCQCDSGFRGERCQSDIDECAGNPCRNGALCENTHGSYHCNCSQEYRGKHCEDASPNHYVSTPWNIGLAEGIGIIVFIAGIVLLVMVFVLCRKMISRKKKRQAEPEDKRLGPTTAFLQRPYFDSKLNKNIYSDIPPQVPVRPISYTPSIPSDSRNNLDRNSFEGSAIPEHPEFSTFNPESMHGHRKAVAVCSVAPNLPPPPPSNSPSDSDSIQKPSWDFDYDAKVVDLDPCLSKKPLEEKPSQPYSARESLSEVQSLSSFQSESCDDNESLAAPDLSKPRGYHWDTSDWMPSVPLPDIQEFPNYEAIDEHTPLYSADPNAIDTDYYPGGYDIESDFPPPPEDFPAPDELPPLPPEFSDQFESIHPPRDMPAAGSLGSSSRSRQRFNLNQYLPNFYPADMSEPQKQGAGENSPCREPYTPYPPGYQRNFEAPTIENMPMSVYASTASCSDVSACCEVESEVMMSDYESGDDGHFEEVTIPPLDSQQHTEV", "length": 4602 }, "evidence": [ { "id": "FB:FBgn0261574", "url": "https://alliancegenome.org/gene/FB:FBgn0261574#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A2R8QAL3-1", "protein_name": "Protocadherin Fat 3a isoform X1", "gene_name": "fat3a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAVSMALWAGIWAILLQLALLLFFTVPPGHCQGERFRLQFTQPLYHASVYENSAARTYASSQVRMGIPLQHHSWEVRYRITSGDEEGFFKAEEYTLGDFCFLRIRTKGGNAAILNREVQDNYVLTVKASLKGDTLEAWTKVSVQVLDMNDLRPLFSPTTYSVTIAESTPLRTSIAQVTATDADIGSNGEFYYFFKERMELFAVHPTSGVVSLSGKLDVDIQSRYDLEIQAVDRGMKLYGNNGVSSTAKLFVHVERINEHVPTLSIVTLAPVWTEKSPIIAVVTVEDLDEGKNGEIETVSIVAGDLLELFSIERTDVPSQEMVDEEDSMKGSNEFVLRAMEQFDWDSYPFGLNLSLQARDRGTPQKLSAVQIVHLRLSRPPPVEVTFQKDQYEVLLSEVAPPGTIVEAVKLQPEPDDAEYILTPSADSGFFSINTMTGVISTARWLTQLKQEVFELEVLEVDSDLRVKVKVILEDANDNAPSFAQQSYEVFVNESVAVGTTVVVVTASDDDHGENGYITYSMASLTPLPFSVQQFTGAVTTTQELDFESSLESFSFVVRASDWGSPYRRESEVNITVHLENVNDNKPLFEKVACVGVVSRELPVGEVIATISAIDIDELELVKYKILSGNERGYFELNPDSGVMTLRHSLITAAPKNSFSLKITATDGEHFSDPMFVNISVVQGKSPPKSFSCTETRVAQRLAEKLLKKAKASSKPKMDEGFIDLFSVNRQTPQFDKSFPTDITVREDVEVGTSVFQVKALDGDTGFNGQLLHAIADGNTDSCFSIGILNGVISIFLPLDREKTDRYLLNITLYDLGQPQRSTWRLLTVYIADANDNAPQFLQDGGYHARISENTPIGTEVIQVEATDKDQGLNGEIQYSLLTSTSQFGINSSSGIVYVAGQLDRELVPLFILKVEARDRAERAAQRFSITTLKITLEDVNDCPPAFIPSVANARALEDLPVGTVIAWLDTQDPDLGLGGQVRYLLDNDYDGRFEVDKTSGAIRLTKELDYETQQFFNLTVRAKDKGRPVSLLSVSFVELEVVDVNENLYAPYFSSFAMNGSVKESVRIGTSVLQVSARDDDTGRDGEVQYSIRDGSGLGRFTIDEETGVIYTTDLLDRETQDSYWLTVYATDLGVVPQSAALQVYIQVEDVNDNSPLTSEPMYHATILENSPKDQSVIQIQAQDPDATTAEPRLSFRISSGNPQNFFSINPRTGLITTTSRKLDREQQAEHVLEVTVSDGGSSPRHTTVWVVIQVLDVNDNKPTFPEKMYQVRLPERSRKQRGAPIYRVFAYDQDQGANAELSYSIIDGNEDGKFIIDAKTGVVSSPKKQFSAGTYDILTVKAVDNGRPQRWATARLHIEWIRRPPPNPIPLAFDEPLYNFTIMETDRVADIVGVVSAQQQGSASLWFDITGPRSFREMFYILQTACGRNCSTEGGDVDSMFDVEKGVGTIVIAKPLDAEQRSFYNLTLEVTDGTNVANTQVHITVLDNNDNPPVFSQPTYDITITEDTPPDTEVVQVLASDRDERHRLTFSLQSSVDPSSMRLFRIDPNSGVIYTARRLDHESRTQHILTIMVKDQEFPYRRSLARVLIGVEDVNDHAPLFTMVMYDGQVYESAALGSAVLTVTALDKDKGQNAQISYSIDSGNTGNTFRIDPVLGIISLARELDLSSIGHYVLSVKATDNGSPALSSTAVVRIAVTLSNNAGPKFPQNEYQAEISESVAIGTSVVTVNALSLSTLTYDIRHGNGHRTFRINQYSGVITTQKSLDFETVSSYVLIVTASNMAGQASNATITVVVLDQNDNAPVFQQLHYRGSISEGAGLNSVVQSDDGQPLVIRASDADRNHNALLVYQIMEESARRFFAVDAGTGSIRTIAQLDHETTPTFRFHVNVRDSGHPQLSAERPAEVTIEVQDVNDCSPKFSQDSYEAVLLLPTYEGVEALQVFATDPDGNGQSELTYSLTDGSLEHFSIEPSTGLLTVRNSTFSKERFRFNVRVSDGRFSSTALVTVLVHEALDSGLAFTHSAYNANIEENNGNITTVAVVTALGNKLNEPLRYTLLNAGGKFRIKPTSGAIETVGVPLDREEKEEYGLLVQAGREEDRLRVARALVRVQVTDVNDNAPVFVGLPYYAAVQVEAEPGTAIFRVTAVDRDKGLNGEVNYFLQDELGHFEVDRVSGELRLRRAFEADLSSVEYQVLVFARDMGTPPLSSSVTFPVTVVNRAMPVFDRPFYSVKVSEDIPVWTPILGINASSPEGQSVLYTITHGDPGTLFSIGFDTGVISVIAGLDYETSPAHRLIVRATDCLTGARAEVDVEVTVLDVNDNPPVFEQPSYKAVISESAMIGTAALQVLATDSDSEKNAAVRYQIIPDRTNSTDHFHIDSSSGLILTARSLDHETIQRYVFLVKATDNGFPPLSSEVWVTVDVTDTNDNAPVFNQLLYEASINELAPKGHFVTCIQASDADRSDAERLQYGLVSGNERMLFELDAASGVLTLSGQRRMQRMPSAITLNVSVSDGVFTSTAQVHVRVERANLHSPQFTQGMYEADVRENAPPGSKVIAIRAQDADPGPFGDVRYVLLSDAARDLFTIDSSGQITTLERLDREERSEMVLSVAAVDAGGRSGYCSVRVTVIDENDNVPLFGASEYHASVRSEVEPGTLVIQVQAWDLDQDANGQVSYSLYSEASLQVTELLDIDPDSGWVVTKGNFAPLRGSVLSFLVKASDGGAPIRHSLVSVYIHVLSADAHIPSFSQPQFSFTVPEDMPIGSLLGAVHLHTSTSHSSLPVSFAAVIGQTPESNSEGVFLVDKESGMIKLDKALDRELTQIYHFKVVAMLQQGRLDAVSAVDVEVKVQDVNDNKPAFESDTYETSVTEGLSPGTRILQVRALDPDWAANGQVTYSLAPPGLLGGSGGEDIEEHGAYFTIDSSSGWISTLKGLDHEQNPAHSLTVWAFDLGDPASQSSSTTITIAVSDSNDNIPQFLQPRYYGSVRESDAPGEVVAVLNTRDNDSSPGNRQVTYHITGGNRGGVFALGLVQGEWKLYVKRPLDREEQERYLINVTATDGLYVSTASVDVTVMDTNDNSPVCEPALYSVSVSEDVPLNKQILRVKATDADTGSNAQIQFSLFGSGAEDFFIHPHTGELKTAVALDREKVSRYSLVARATDGGGLWCEAEVVVDLLDVNDSPPMFSMPHYTTSVYENTATKALLTRIQAIDPDLGVNRKVVYSLVDSADGFFSIDKSSGIVVLERLLDREIQSSYHIVVRASDQGVPVRLSSLANITITVLDINDNPPVFERRDYLATLPEDVAVGTEVVQVYAASKDIGTNADIYYNIRSGNQQGHFTINVNTGAISVSRALDFESCKDYFLTVEATDGGTPPLSAVTMVNINLTDVNDNAPIFSRDAYSVSISEDANIGDTVVKVMAEDVDSYVNGDILYSIISGDRENQFFIEPITGQIKVNKQLDRETMAGYSLSVRALDSGTPAMSSTVLVNIDISDVNDNPPTFTPANHTAVIQENKPLGTSVLQLSVIDKDASHNGPPFHFHILSGNEGAWFKLDREGLLTSNQVFRRSEGTEYVIHVQASDSGRPPLSSVASVLVRVIEESVHKPAASPLHVHIVTMEDEFPGGVIGQIHATDQDAFDILTYGHTHQQSSLFKVSPRDGRIIALSGLDAGRYTLNATVTDGRFTVSVPVSVHVEQASVEMLHDAVTVRFDRVSPHDFISRHLPSVRRVLSSVMSTSRPDALHVLSVQPVEATGQLDLLVAVESAEGGGFYKAALVTQKLSSARRQLDQVLRVSAVLDKNCSGLDCREAQCEQTITLDSHSLLTYSSTKTSFVSPKFHRNTRCVCSDGSCSAASEVCADMRCPGDMQCVGTDSSRGPYACQCPPGKLGECAGHTSLSFSGNSYIKYRVTDGERSGEMKLALRIRTLQSKGIIMYTRADPCSVLKIEEGKLWFQLDCGNSPRSIGISGRLVNDGNWHHVVLELRGNYSSLSLDDMYVERRLTTAKFRPLEADLSIYFGAQVLPPDARSLTEMKGPRVTNGFQGCLDSVVLNDNELPLQNKRSPYAEVVGLTDLKLGCVLYPDACVAQPCLNGATCISLPSGGFSCSCSALHTGGRCETEISVCMPNPCQNGGVCKPIGNAFICSCKRGYTGATCEEDVNECERELCENGGICINTFGSFYCNCTPGFVGSACSVRPVLVPDMQAGHAYVGKEELIGIAVVLFLILTLILLFIAFRKKVFQKSYSRNNLSLVQDPATAALLHKANGGHYPPLRCAIGEPISLYTEGGITGPPQVPVRPMAYTPCFPGDARGTLEKRDGRGSELTEMSTFHPSESPRILGGTNRRGVVVCSVAPNLPPVSPCRSDCDSLRKSPWEEDGKVDLLEEVTCFSGSNKGSNSEVQSLSSFQSDSCDDNASIVTVIRLVNDAVDTIENEVSVMDQGQNFNRAYHWDTSDWLPSTRLPDIEEVPTYETPEVGVALESDYYLGGFDIDSDYPPPQEEEFMSQDQLPPPLPTEEFDTSPANQPVSRESTLSGDRKPRPHFHPSQYLPPHQLPLGSTGEEFSTFTGREERLSVNASSASSVSSAPCGFEDSETGGSLDSFEDMHPHTQQTEV", "length": 4601 }, "evidence": [ { "id": "HGNC:23112", "url": "https://alliancegenome.org/gene/HGNC:23112#orthology", "database": "AGR" }, { "id": "MGI:2444314", "url": "https://alliancegenome.org/gene/MGI:2444314#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-1254", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-1254#orthology", "database": "AGR" }, { "id": "Q8TDW7", "url": "https://omabrowser.org/oma/group/Q8TDW7/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8I6AQL3-1", "protein_name": "FAT atypical cadherin 1", "gene_name": "Fat1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRHLALLLLLLLFLQHFGDGDGSQRLEPTPSLQFTHVQYNVTVHENSAAKTYVGHPRKMGIYILDPSWEIRYKIISGDNENLFKAEEYVLGDFCFLRIRTKGGNTAILNREVRDHYTLVIKAVEKVTDAEARAKVRVQVLDTNDLRPLFSPTSYSVSLPENTAIRTSIARVSATDADIGTNGEFYYSFKDRTDMFAIHPTSGVVVLTGRLDVLETQRYELEILAVDRGMKLYGSSGVSSLAKLTVHVEQANECAPEITAVTLSPSELDKDPTYAIITVEDCDQGANGEIASLSIVAGDLLQQFKTVRSFPGSKAFKVKAVGGVDWDSHPYGYNLTVQAKDKGTPPQFSPVKVIHVISPQFRAGPVKFEMDVYRAEISEFAPPHTPVVLVKAIPSYSHLRYVFKSTPGKPKFGLNHNTGLISILEPIKRQHTTHFELEVTTSDRRASTKVVVKVVGTNSNPPEFTQTSYKASFDENAPVGTPVMRVSAVDPDEGENGYVTYSIANLNHVPFVIDHFTGAVSTSENLDYELMPRVYMLRIRASDWGLPYRREVEVLATITLNNLNDNTPLFEKTNCEGTIPRDLGVGEQITTVSAIDADELQLVRYQIEAGNELDLFGLNPSSGVLSLKHSLMDGLGAKVSFHSLRITATDGENFATPLYINLTVAASRKPVNLRCEETGVAKMLAEKLLQANKLHHQGDAEDIFFDSHSVNAHAPQFRGSLPTGIEVKEDLPVGASILFMNATDLDSGFNGKLVYAISGGNDDSCFTVDMETGMLKVLSPLDREVTDKYTLNITVYDLGIPQRAAWRLLDVTVLDANDNAPEFLQESYFVEVSEDKEINSEIIQVEATDKDLGPSGHVTYAILTDTEKFAIDRVTGVVKIIQPLDREVQRVHYLKIEARDQATEEPWLSSTVLLKVSLDDVNDNPPRFIPPSYSVKVREDLPEGTIIMWLEAHDPDVGQSSQVRYSLLDHGEGHFDVDKLSGAVRIVQQLDFEKKQLYNLTVRAKDKGKPASLSSTGYVEVEVVDVNENLHAPVFSSFVEKGTVKEDVPMGSSVMTVSAHDEDTGRDGEIRYSIRDGSGVGVFRIDEETGVIETSDRLDRESTSHYWLTVYATDQGVVPLSSFIEVYIEVEDVNDNAPQTSEPVYYPEIMENSPKDVSVVQIEAFDPDSSSSDKLTYRITSGNPQGFFSIHPKTGLITTTSRKLDREQQDEHILEVTVTDNGVPPRSTIARVIVKILDENDNRPQFLQKFYKIRLPEREKADGDRSAKREPLYRVIAADKDEGPNAELSYSIEEGNEHGRFSIEPKTGVVSSKKFSAAGEYDILSIKAIDNGRPQKSSTTRLHIEWISKPKPSLEPISFEESVFSFTVMESDPVAHMIGVISVEPPGMPLWFDIIGDALAREAFYIFQMTCDLNCTAEGGNYDSHFDVDKGTGTIIVAKPLDAEQKSSYNLTVEATDGTSTILTQVLIKVIDTNDHRPQFSTSKYEVSVPEDTEPETEILQISAVDRDEKNKLIYTLQSSIDPASLKKFRLDPATGALYTSEKLDHEAIHQHVLTVMVRDQDVPVKRNFARIIVNVSDMNDHSPWFTSSSYEGRVYESAAVGSVVLQVTALDRDKGRNAEVLYSIESGNIGNSFTIDPILGSIKTARELDRSHQVDYDLMVKATDKGEPPMSEMTSVRISVTVADNASPKFTSKEYSAEISEAIRIGSFVGMVSAHSQSSVMYEVKDGNIGDAFNINPHSGSIVTQRALDFETLPIYTLTVQGTNMAGLSTNTTVVVHIQDENDNPPAFTRAEYSGFISESASVNSVVLTDKNVPLVIRATDADRESNALLVYQIVEPSVHNYFAIDPTTGAIHTVLSLDYEETRVFHFTVQVHDMGTPRLFAEYAANVTVHVIDINDCPPVFSKSLYEASLLLPTYKGVNVITVNATDADSRAFSQLIYSITKGNIGEKFSMDHKTGTIAIQNTTQLRSRYELTVRASDGRFTSVASVRINVKESRESPLKFTQDAYSAVVKENSTEAKTLAVITAIGNPINEPLFYRILNPDRRFKISHTSGVLSTTGIPFDREQQETFVVVVEVTKEREPSAVAHVVVKVTVEDQNDNAPVFVNLPYYAVVKVDAEVGHVIRHVTAIDRDSGRNGDVHYYLKEHHDHFEIGPSGDISLKKQFEHDTLNKEYLVTVVAKDGGNPAFSAEVLVPITVMNKAMPVFEKAFYSAEIPENVQTHSPVVHVQANSPEGLKVFYSITDGDPFSQFTINFNTGVINVIAPLDFESHPAYKLSIRATDSLTGAHAEVFVDIVVEDINDNPPVFVQQSYSTTLSEASVIGAPILQVRATDSDSEPNRGISYQLIGNHSKSHDHFHIDSHTGLISLVRALDYEQFQQHKLLVRAVDGGMPPLSSDVVVTVDVTDLNDNPPLFEQQVYEARISEHAAHGHFVMCVKACDADRSDLDRLEYSILSGNDHKSFVIDGETGIITLSNPRRHTLKPFYSLNVSVSDGVFRSSARVNVTVMGGNLHSPVFHQNEYEVELAENAPLHTLVVQVKATDRDSGIYGHLTYHLVNDFAKDRFYVNDGGQVFTLERLDREAPAEKVISVRLMAKDAGGKVAFCTVNVILTDDNDNAPQFRSTKYEVNVGSSAAKGTSVVKVFASDADEGSNADVTYAIEADSESVEENLEINQLTGLITTKESLIGLENEFFTFFVRAVDNGSPPKESVVPVYVKILPPEVQLPRFSEPFYTYSISEDMPIGTEIDLIRVEHSGTVLYTLVKGNTPESNRDEFFVIDRQSGRLKLEKSLDHETTKWYQFSILARCTLDDYEVVASIDVSIQVKDANDNSPVLESNPYEAFIVENLPAGSRVIQVRASDLDSGVNGQVMYSLDQSQDADIIESFAINMETGWITTLKELDHEERASYQIKVVASDHGEKVQLSSTAIVDVTVTDVNDSPPRFTAEIYKGTVSEDDPPGGVIAILSTTDADSEEINRQVSYFITGGDALGQFAVENMQNDWRVYVKKPLDREQKDSYLLTVTATDGTFSSKARVEVKVLDANDNSPVCERTAYSDAIPEDALPGKLVMQVSATDADIRSNAEITYTLFGSGAEKFKLNPDTGELRTLALLDREEQAVYHLLVKATDGGGRSCQATIVLTLEDVNDNTPEFTADPYAITVFENTEPGTPLTRVQATDADAGLNRKISYSLLDSADGQFSINEQSGILQLEKHLDRELQAVYTLTLKAADQGLPRKLTATGTVVVSVLDINDNPPVFEYREYGATVSEDIVIGTEVLQVYAASRDIEANAEITYAIISGNEHGKFSIDSKTGAIFIIENLDYESSHGYYLTVEATDGGTPSLSDVATVNINITDINDNSPVFSQDSYTTVVSEDAALEQPVITIMADDADGPSNSHILYSIIEGNQGSPFTIDPVRGEIKVTKPLDRETISGYTLTVQAADNGNPPRVNTTTVNIDVSDVNDNAPLFSRDNYSVIIQENKPVGFSVLKLVVTDKDSSHNGPPFSFAIVSGNDDNMFEVNQHGVLLTAATVKRKVKDHYLLHVKVADNGKPQLSSLTHIDIRVIEESIHPPAILPLEIFITASGEEYSGGVIGKIHATDQDVYDTLTYSLDPHMDGLFSVSSTGGKLIAHRKLDIGQYLLNVSVTDGKFTTVADITVHIQQVTQEMLNHTIAIRFANLTPEEFVGDYWRNFQRALRNILGIRKNDIQIVSLQPSEPHSHLDVLLFVEKSGGTQISTKQLLHKINSSVTDIEEIIGVRILDVFQKLCAGLDCPWKFCDEKVSVDENIMSTHSTARLSFVTPRHHRTAVCLCKDGTCPPVHQGCEDNPCPAGSECVADPREEKYSCVCPGGGFAKCPGSSSITFTGSSFVKYRLMENENRLEMKLTMRLRTYSSHAVVMYARGTDYSILEIHTGRLQYKFDCGSGPGIVSVQSIQVNDGQWHAVSLEVEGNYAKLVLDEVHTASGTAPGALKTLNLDNYVIFGGHLRQQGTKHGRNTQVANGFRGCMDSIYLNGQELPLNNKPRAYAHIEEWVDLAHGCLLTATEDCSSNPCQNGGVCNPSPTGGYYCKCSALHAGTYCEVSVNPCSSNPCLYGGTCMVDNGGFVCQCRGLYTGQRCQLSPYCKDEPCKNGGTCFDSLDGAVCQCDSGFRGERCQSDIDECAGNPCRNGALCENTHGSYHCNCSQEYRGKHCEDATPNHYVSTPWNIGLAEGIGIIVFIAGIFLLVVVFVLCRKMISRKKKHQAEPEDKRLGPTTAFLQRPYFDSKPSKNIYSDIPPQVPVRPISYTPSIPSDSRNNLDRNSFEGSAIPEHPEFSTFNPESMHGHRKAVAVCSVAPNLPPPPPSNSPSDSDSIQKPSWDFDYDAKVVDLDPCLSKKPLEEKPSQPYSARESLSEVQSLSSFQSESCDDNASIVTVTHLVNAVVDTVNKEESLAAPDLSKPRGYHWDTSDWMPSVPLPDIQEFPNYEVIDEHTPLYSADPNAIDTDYYPGGYDIESDFPPPPEDFPAPDELPPLPPEFSDQFESIHPPRDMPAAGSLGSSSRNRQRFNLNQYLPNFYPVDMSEPQKQGAGENSTCREPYTPYPPGYQRNFEAPTIENMPMSVYTSTASCSDVSACCEVESEVMMSDYESGDDGHFEEVTIPPLDSQQHTEV", "length": 4644 }, "evidence": [ { "id": "FB:FBgn0261574", "url": "https://alliancegenome.org/gene/FB:FBgn0261574#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PBP8-1", "protein_name": "Protocadherin Fat 1 isoform X1", "gene_name": "fat1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSLKSPVTMGKSWTNHLLVLFMWICLGAQQMEDALPFQFTYPFYDVTIYENSAAKTYVECPIKMGIFMTNQSVDIWYTIESGDHDNLFKAETYVLGNFCFLRIRTKGGISASLNREIKDHYLLTINAIERHTGAEAQTQVKVQILDMNDLRPLFSPTTYSFFVPENSAARTSIGRVSATDADTGTNGEYYFSFKEWTDMFSIHPTSGVITLTGKLDYSEMALYEIDVLAVDRGLKLYGSSSSSSAAKLKVHVLQANEHSPVITAVPLTPWNTTSDPTYAHVTVEDADEGQNGEIASLNIVAGDPLQQFKTFRTNPGSKEYKIKAVKKVEWEGYSFGYNLTLQAKDKGNPPKFSSAIVVRLGSPSEYTEIPRFEKSIYRVTLSEFAPPHSPVVMVKTVEKHSKINYLLEFKMQQHDNPFIINPNTGLISTSGPIKAEKVSQYEFEVVTSDRRASTKVVVSVSDMNNNAPVFQKSNYEASIAEHVPIGTSVLTVSATDMDDGENGYVTYSIVNVNKQPFVVDYFTGVISTTEDLDYETMPSKFSLRIRASDWGSPFRREAETIVSISLTNLNDNKPQFENIDCDVRVPRSLGVDEQIIRVSAIDADDLGVVQYRIDTGNNMNLFKLDSTSGVLALKKSLRDGDAVKQSFHRLQITAGDGEISSTPLFLNLTIVNAPKHVRSKCAETGALRTLAGLLLFGSKLDSQKETEDEFADIHSVNRHAPRFIESTPAVIEVKENLPVGTSVALLRAADSDSGFNGKLLFVISGGDFDSCFTIESDTGWLKVFQPLDRETTDRYTLKITVYDLGLPQKSSSHLLDVKILDANDNSPEFLQREYIVDISEDTAIGTDIIQLEAKDKDLGVNGMVRYSFLTETDKFNIHEETGFVSVMRVLDREANPVFVLRVAAFDAAIDEPKLVSTVLLRINLEDVNDNPPMFVPQHYHIRVREDIPVGTLVLWLETHDPDLGLSGQVRYSLTDGDDGNFQVDKMSGAVYVSQTLDFETRQIYNLTAKAKDRGRPNPLSSSCFIQVEIVAVNKNMYRPNFPFFVDWGTVLEDASVGTSVLKVAAHDEDSGRDGEVRYSIQGGSGLGVFTINEESGIITTQEILDRETKNHYWLTVYATDQGIVPLSSFVEVYIEVQDVNDNAPLTTEPVYFPSVSENSPKGVSVIQIQAFDLDSESSENLSYKISSGNPQGFFDIDFQTGLVTTTSRKLDREKQAEHLLEITVSDDGSPSKSTVVHVIVNVLDENDNSPQFLEKIFKIRLVERLEAVEWEPIYRVIAYDRDESPFSDISYAIEEGEEQGKFFIEPTTGFVFSKEAFSAGEYNIITIKASDNGKPSKSSICRLHIEWIPKPKLAKQALAFEEIPLSFSVMENDPVAHMVGVISAQPLDSPVWFTIKGDTHVKDAFHILQMSCDLNCTAGGSTDSRFDVEKASGTIIIAGALDAERQSNYNLTVEATDGTRSISTQVIVQVLDTNEHRPKFSQNQYEISIPEEIQPGMKILEINATDKDEDNKLSYTLLSSTDLFSLKKFRLDPGIGFLYTTEKLDHETMHRHILTVMVRDQGVPVKSNVVRVIINVEDSNDNPPWFTSSQYAARVFETAAIGSSVLQVTALDKDKSFNAEILYSIDSGNHGTSFIIDQSSGIITVARELDCETRDQYELIIKASDKGEPSLSAVTAVRITVTISDNTKPKFPSNSLSAEVSENVPVGSFVTLVSAFSQSTVFYQIIEGNEKGAFDINPNSGAVITRKKLDFETLSSYKLIVQGTDMAEMSSSVTVNIYLKDENDNAPVFTQSEYTGFISESAIIRSVVLNSQKAPLVVRATDADQHSNARLVYQIMEPFACNYFSIDSRTGAIQTLSNLDYEQRRIFNFRVQVHDTGNPRLFAQDTANVTIHIININDCAPKFTQDSYEATLLLPTYKGVKVITVKATDEDSLPGNKLHFEIVDGNIGNKFWLDPTFGDIFVQNTTQLRSRYRLTVQVSDGSFIGCANVKVNVKDNKSHNLKFTQDIFTAQVQENATEKKTLAVLSVVGNRVNEPLFYSILNPNSKFEIGRTSGVLFSTGIPFDREEQDLFEIIVEVIKEPGLNGPAHVLVKVQVEDVNDNAPFFVDQPYHAVVQVDQTVGSVFAKVTTVDRDIGKNAEITYYLKGHDKYFQVNPFGEISLKRPLELESIGKYVINITAQDEGEPPLFSNAEVVISVVNKATPIFERPFYKIEILENVLVGTSILQVVANQSAGPRTVYSISGGNPFSQFDIHFNSGLIKVIQPLDYEAHPAYRLSIQATDSLTGANSDVFVDIILEDVNDNAPKFEAAVYSISISESTVIGTSVLQVVAMDPDAQSNAILFYKLHERDGSTSDHFRIDAETGVIWTAGLLDHETQSQHDLIVKAVDGGAIQLSSEVQVTVYITDLNDNPPIFAQQLYNATISKISSPGQLVTCVKAFDADSHGSSNLEYAILSGNDNNIFAIDALSGEIVIANISRQSLKHFYSLILSVTDGVFCASAEANIYVMGENSHSPSFTQDEYLIELAENSPVGTLVGQVEAIDEDPGKYGQLTFFIMNDIARDKFNINEDGQIYTEESFDRENPEEKIIRISLMAKDGGGLLGFCNVIVILSDVNDNSPKFKHSEYKVTVPRDAPSSTTVIKTTAVDEDEGSNADIVYTIESDIDHFEIHSLSGAIVTKESLIGLENGLYSFFVKAKDSGSPPKQSIIPVSIRIVPPETSIPKFAEPSLWLELSEDLAVGTEMDIFQAENELSVIYSLVGGNTPESNKHDVFAIDSTTGKLILTKRLDYETIKWYHLAVQVRDVKDDMEMISTVDVSVHLKDVNDNSPQFESFRYQSCIAENLPKGTSVVQVKATDLDSWLNGQITYALHENQQPPDVLQLFSVNSETGWITTLMEIDREKTDQYRITVVATDGAQGLQMTGTTVVEVTVVDTNDNPPLFTEAVFKGAVREDESTPGTVVTILSYVDSDSDEVNRRFNCFITGGDPQGLFDVKHTDGVWVVAVSKTLDREERDFYLLNITATDGTFVAKAAVEITVLDANDNSPVCEKDVYAQAVPEDVLIGKHILQVSATDADIQSNAEITYQLSGSGAESFTIDSKTGAVKTLATLDREVTDVYNLTVRAVDKDNHFCQASLLITVEDANDNAPKFTSDPHHVSIYQNTQPGTYVARLEAFDADIGMNGKIRYSFEDSAGGLFSIEESSGIISLERSLDKQMKAMHVLRVRATDQGFPHRLSSLGSVLVTVLDANDHPPVFERREYISTVPEDVTIGTKLLKVFASSKDRQMTSQTTYSFSSGNEQGAFRIDSQTGDIFVMEPLDYEESSQHYLTVKATVGGKQSLSDMATVSIHLQDINDNSPVFSQKIYSAVVSEDTRLASTVLTVLANDLDGPLNNQIRYSIEESNQSCPFIMDAVSGELQLARQLDREMVASYMLTVMASDSGSPLKSDSAAINIAVSDVNDNPPVFSQANYSLIIQENLPSGTSVLQLNVTDNDSLHNGPPFSFILIGVEANPFSIDQQGLVKTAGPLTKGQYTLQVQVSDNGKPPQKSVTSITVLVAQASMFPPSVFPLEIFIILLEDEYSGGTLGKIHATDQDEHDKLAFSLDPQSHSLFSIIGTDGRLLAREGLDVGHYQLNVSVSDGHFSVSSIVKVNVLQVTEQMLDSSISIRFAGITTEDFIQDHWKNFQKMLRSVAGARRGAINLISLQSAGFGDGLDVLLYFERPRRGAGALEALSQKISSSRGAIKEMTGLHVVRVLNSRCLSSECPDGKCRRVLLFNQTTMGAYSTARVSYITPRHHMTAKCLCTDSKCLKQEYTCVNSTCPEGYECVSGFGQDKHSCICTGAAKVKCSGGSSMTFSESSYIKYSLMESMKGLKLTLKLKTLSTEGTIMLARGTGHSILEIAGGRLQFQFDCGWGFATVSVHSVLVNDGQWHMAELEVKGNYARLVLDQLHSASGIAPGPLHCLNLGEQVVLGGHAQHLGSRRRRNLPASNSLQGCMDSVLLNGHRLSLDSGGPLGVTIEDMVGVSPGCFGFTSPVCSSNPCLNGGSCLMRQSGGNICKCSPSFSGTRCEVKISPCDSNPCLYGGTCIQNNLDYSCKCRGKYSGQRCQIGPYCKENPCQNGGQCIDSLDGAICECEPGFKGERCMIDVDECVDRPCFNDGHCVNTRGSFTCSCMIGFSGRLCEIGTEVSNQPISSSWNSWIGELVAILAFLAVIFVVTLLFLIVWKGSCKRIKRDKDLDKVKDIDSYIQRLSFYNHGKNKSRSDTPPLVPVRPISYTPSIPGECRNNRGSVPEFSNFTADPLFGLRKSVAVCSVAPNLPHRKASYSHSENDSIQQMDWDEEYDEKILDLTSCLAMEDDYISLSRDNRGLQSTCSLQSDVMDDNSYYWDTSDWQQNIYSPGIQGFLQYEFVQMTSPIHTSPETVHMDFTTVGEDIETFLPLTTLLPNSDQLTRPEGHHAIHPTVRSNFMTSSQHPSPDSPESVQTTAEMLQDQHIRSSETVDFLESPV", "length": 4503 }, "evidence": [ { "id": "FB:FBgn0261574", "url": "https://alliancegenome.org/gene/FB:FBgn0261574#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PRG7-1", "protein_name": "Protocadherin Fat 1a isoform X1", "gene_name": "fat1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQNHMTSLLVVLLLLCGCTANQSQDNAPIPLFTQSVYNATIYENSAAKTYVESPVKMGIYITDPTWEIRYKIVSGDNENLFKAEDYHLGDFSFLRIRTKGGSSAILNREVRDHYILTVKAMEKNSNAEARTRVRIQVLDTNDLRPLFSPTAYSISLPENTAIRTSVAKVMATDADIGTNGEYYYSFREWTDMFSVHPTSGVVTLTGKLDYSETKQYELEILAVDRGMKLYGSSGFSSMAKLTVRVDQANEHAPVITAVTLAASETDKDPTYAVVTVEDNDQGANGEIASLSVVAGDPLQQFKAMRTSPGSKEYQIKAVKQVDWDSQPFGYNLTLQAKDKGNPPQFSSAKVIHVMSPHFKVGPPKFIQAIYRVNVSEFAPLHTPVVMVTAVPKYPQLKYAFRHRLDKNHFAINPDSGLITTAAPLHADSVNKYELEVVTSDKKAVTKVIIDVIDVNNNGPEFKQTSYKASLDENMPTGTSVLTVKATDLDSGENGYVTYSIANVNSQPFVIDYFSGVISSSETLDYELMPRIYTLKVRASDWGSPYRREVETQVTIMLNNLNDNKPLFENVDCDATVPRDHGVGDQITTVSAIDADELQLVRYRIKAGNDLNVFEMNPSSGVLSLKQTLSEGEAAKVSYHSLQIIASDGEHETQPMFLNITVVTAHKPVQVKCVDTGVASMLAEKLLQGSKVHTQSEPEDHFQDFHSVNRVAPQFADTFPSVIEVKEDLPVGARIVHLSASDSDSGFNGKLVYVISGGDAESRFIIDMDSGWLKVFAPLDRETTDHYTLNITVYDLGIPQKSSSRLLDVKILDANDNSPQFLKETYSVEISESSTVGTEVIQVEAKDKDLGDNGVVRYSILADTDQFAIDTETGIVTVKKPLDREVQPVFVLKIAARDQATAEPQLVSTVLLKITLEDVNDNPPKFIPPNYHVRVREDLPIGTVIMWLEAHDPDVGPSSQVRYSLIDSGDGKFEVDKLSGAVRIVQNLDYEKKQVYSLTAKAKDKGKPISLSSSCHIEVEVVDVNENLYRPLFPSFVDKGFIKEDVPIGTSVMKITAQDEDKGRDGEIRYSIRDGSGLGIFTIDEDTGVIRTQELLDHETVPHYWLTVYATDRGVVPLSSFVEVYIEVQDVNDNAPQTSEPVYYPSVMESSPKDVSIIQIEAFDPDTKSSEKLSYKITSGNPQGFFSINQKTGLVTTTSRKLDREQQDEHILEITVSDQGVPAKSTTVRVIVKVLDENDNSPQFMEKVYKIKLPVREKPEKERALKRDPVYRVIASDKDEGPNAEISYSIEEGDEQGKFFIEPKTGMVYSKKLSSAVDYDILTIKAVDNGRPQKSATCRLHIEWIPKPEPSTVPLVFDEPFYTFSVMESDTVSHMLGVISLEPVDTPVWFEITEDIAAKELFYIVQMACDLNCTAEGGNSDSRFEVGKASGTMIVAQALDAEQKSHYNLTVNATDGTRSVSTQVLIKVIDTNNHRPQFSKPKYEVDVSEDTPPETEVLRITATDQDEKNKLTYTLLSSTDPFSLRKFRLDPGTGVLYTAERLDHETMHQHTLTVMVRDQDIPVKRNLVRVIVNVQDTNDNAPWFSGAPYVGRVFESAATGSAVLQVSALDKDKGQNAEIIYSIESGNVANSFAIDPVLGTITVAKELDRNNKNRFELTVKASDKGTPPLSGTAAVDITVTISDNAIPKFAEKEFSAEVSETVLPGAFVSLVTANSQSSVFYQIKDGNVNGAFDINPNSGVVVTHSVLDYETIPSYKLTIQGTNMAGLASNTTLLIHLKDENDNAPVFIQDQFAGMVSESSPVNSVVLTKDNTPLVIRALDTDRDANSRLVYQIVEPFAHNYFAIDSSTGAIRTISELDYEQRSVFRFSVQVHDMGIPRHFAEKAANVTIEILDVNDCPPQFSQDLYETTVLVPTYKGVEVITVNASDADSGPNSRLFYSIVEGNIGEKFKMDPVTGVITIQNVTQLRSRYELRVRVSDGRFSKTSLVKINVRENKESTLRFTQESYKAFVPENSSEKKTLAVIAAVGNQVNEPLFYTILNPDKRFTISRTSGVLSSTGTPFDREEQGVFDIVVEVTRDDKSPDVAHVLVTVIIEDVNDNPPVFVNLPYQALVQVDADVDHIITKVTAVDADINENAEINYHLQELNEFVQISTDGEISLTKKLDKDSVNTEFIITVVARDGGEPALSSSVEVPILVVNKAMPVFEKAFYSLEIPENIQLLTPIVHIQANDSEGPRIVYTITEGDPLNQFTINFNTGVIQVVKTLDFETHPAYKLSVRATDSLTGAKAEVFVDIILEDVNDNPPVFHTKLYNASLSEASVIGTSVLEVSATDADTGNNKVLFYQIVEDKDKSFDYFSIDRDTGTIWTTRMLDHEEKPSHRLLIRAVDGGVPALSSEVMVLIDVMDLNDNTPVFSQNVYEATVSELAPRGHFVTQVQASDADISDSGKLEFSILSGNEGQNFAMDPNTGALVISNHRKPHMESLYNINVSVSDGVFRSSAIVKVNVISANFHNPTFNQVDYVVELLENSPVGTLVAEAQATDDDSGTYGRLTYHIVNDIAKDKFSISENGEIFTLESLDRENALEKVIPISLIAKDGGGKVGFCTVNVILTDINDNAPQFRAADYRVNVASDVSRGTTILKIAASDMDEGSNADITYSIETDADNVEENFEIHQFSGVIVTKESLIGLENQMYTFLVRAKDGGNPTKSSVVPVYVKILAPEVPVPKFIESHYRFAIEEDLSLGSEIDVIQAESDQPVFYSLVKGNTPESNQDEVFVVDPSSGSLKLDKKLDHESTKWYQLTLQAQSEYEGSKVVSAVDISIQVKDVNDNRPLFESNPYEAFVVENLPGGTSVIQVKATDLDSGTNGHVVYNLDPNQETRDIVELFAINSESGWITTLKELDRETRNKYTVSVLATDRGDKVQLMASTRVDVTVVDVNDNPPKFTAEIYKGTVSEDDPPGGVIAILSTTDLDTEENNKQISYFITGGDPLGQFAIEHTQGEWKVSVRKPLDREEKDNYLLNITATDGTFTAKAVVEVKVLDANDNSPICEKSFYMESVPEDSPAGRLILQVSATDADIRSNAQISYELLGPGSEHFSIDSETGELKTLLPLDREEEEVHKMKVRALDGGGRFCEAEVEITVEDVNDNPPQFTTDPYTFTVFENTEINTPVARLYASDLDTGANAEILYSLLDSADGVFSIEEETGVVRLDRPLDRELQSLYTLRAQATDRGSPRHLSSHTTVSVSILDINDNPPVFERREYTATVAEDIPVGTQVLRIHAASRDTEAGTEITYAIINGNERGAFRVDPQTGGVFVIEPLDYETAHEFYLTVEATDGGTPSLSDLATVNINLTDVNDNSPVFNQDIYSAVISEDAELGKTVLTVMADDADGPSSNQVRFSIIDGNQGSPFTIDPVRGEVKVARLLDREKTSGYTLTVLASDNGSPARSSSATINVDVSDINDNPPIFSQANYSIIIQENQPIGASVLQLTVSDRDASHNGPPFTFSIIRGNEGDFFRITPQGVLVSAATLSRQTQEFYLLQAQVTDSGRPPLVSTAFVSVRLIEESIYPPSILPLDIFITTATDEYSGGVLGKIHATDQDVYDTLTYSLAPDSSSTSENSGLFSVSPADGKLVARGNLDAGQYVLNITVTDGRFTAAARVNIHVRQATAQALDNSIAVRFSAIAPEEFIGDYWRNFLRALRNIAGVRRGDVQLVSLQPAADASGDLEVLLALERSGSPFQPQEVLYRKLNASVGVIEEMTGVRIVRVMKKLCAGLDCPLSFCQETIALETGAVSAYSTARISFVTPRHMRTAKCLCEGAECSILSKLCEGSPCPDGMECVEDPTHSKYRCICPEGKQEECSERQSLTFSGNGYARYRLMENENKEEMKLSLRLRTFSTHATVMYAKGTDYSILEIVNGRLQYKFDCGSGPGVVSVHSTQVSDGQWHTVSLEVDGNYARLVLDQVHAASGTAPGTLRTLNLDTSMYFGGHVRPASGSGRLVMNGLRGCLEGIVFNGRELPLSQVRGAHSVLEELVEAAPGCSLAPPIQGCTSNPCTNGGTCLALPNGGYFCKCTAAFMGTHCEVTISPCASNPCLYGGTCIPRGGDFYCQCRGQYSGQRCQLGPYCTDNPCKNSGKCIDSLDGPVCECEPGFQGERCLSDVDECLKNPCGNGGHCQNTYGSFSCNCSNGYSGQHCELRSEIRNEFVSTSWNIGLEEVIGIVVFVASIFFLVLLFVVVRKRICRRSKSKSDDDDKIGISTGTQNSFLHRPYFDAKLNRNIYSDIPPQVPVRPISYTPSIPSDSRNNLDRNSFEGSAIPEHPEFSTFNPDSVHGHRKTVAVCSVAPNLPPPPPSNSVSDSDSIQKPSWDYDYDAKVVDLDSCLSKKPVEDSACHPYNTRGSMSEVHSLSSFQSESCDDNASLVTVIHLVSSVVDSVEKEESFSAHEHKNPRGYHWDTSDWMPSVQLPGIQEFPQYEVVEAPPTLYSDPALLDTDYYPGGYDIESDFPPPPDDFPSHDDLPPPPPVPEYGDRYDTLQPASRGLNSTPSSPGGSSIRHRPPLPQLYSLTQFLPHHHYSSDPEPQTNPTSTSTSSSTEGYRHGGFSLGYRRDFDPPAADNMSLSLYTSTASCSDMSACCEESEVMMSDYESGGEEGAQFQRLIIPPLDSQHQQHTEV", "length": 4666 }, "evidence": [ { "id": "FB:FBgn0261574", "url": "https://alliancegenome.org/gene/FB:FBgn0261574#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0XZB0-1", "protein_name": "Protocadherin Fat 3", "gene_name": "FAT3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEMNMGHWSGTRPPPPCLALLLAELLASLFQVAHGATPLGFHFTHSTYNATVYENSAARTYVNSQTRMGITLSDLSWDIKYRIVSGDDEGFFKAEEVVIADFCFLRIRTKGGNSAILNREIQDNYLLVVKGSVRGEDLEAWTKVNIQVLDMNDLRPLFSPTTYSVTIAESTPLRTSIAQVTATDADIGSNGEFYYYFKSKVDLFSVHPTSGVISLSGRLNYDEKNRYDLEILAVDRGMKLYGNNGVSSTAKLYVHIERINEHAPTISVVTHIPFPSDKEPTYAVVNIDDLDEGANGEIESVSIVAGDPLEQFFLIKEGKWMNEYKIKERKPIDWDSFPYGYNLTLQAKDKGSPQKFSAVKLVHIASPKKESIPLKFEKEAYDVSVSEFSPPGVVVAVVKLMPEPLGVEYRISPSEGAENFKINPITGLITTARSLKIIEKDLYELEVYTNKGDDLKAQVTIRLEDANDHTPEFQQTSYSSFVNESVPVGFSVLAVSAVDKDRGENGYITYSIASLNSLPFIINQFTGVISTSEELDFESSPESYRFIVRASDWGSPYRHESEVNVTIYIGNVNDNKPLFEKVACQGVISSDFPVGGHITAVSAIDIDELELVKYKIISGNELGIFYLNPDSGVLQLKKSLINSGIKNSNFGLKITATDGENFADAMFVNISVVHGKVSSKTFSCRETRVAQRLAEKLLKKAKANVKLNLEDGFLDYYSVNRQAPHFDKTFPTDVMVSEDLPVGATILRIKAYDADSGFNGKVVYTISDGNADSCFNIDIETGVLKVLMPLDREKTDLYILNITIYDLGNPQKSAWRLLTVTVGDANDNKPIFLQDSYSVNILESTSLGTEIIQVEARDKDLGSNGEVTYSVLTDTQQFAINSSTGVVYVADQLDRETKANYTLKIEARDKAESGHQQFSVVPLKVFLDDVNDCSPAFIPSSYNVKVLEDLPVGTVIAWLETHDPDLGLGGQVRYSLVNDYNGRFEIDKASGAIRLSKELDYEKQQFYNLTVRAKDKGRPVSLSSVSFVEVEVVDVNENLYTPYFPDFAVIGSVKENSRIGTSVLQVVARDEDSGRDGEIQYSIRDGSGLGRFSIDEETGVIYTADVLDRETTKSYWLTVYATDHGVVPLYATIEVYIEVEDVNDNAPLTSEPIYYPSVMENSPKDVSVIQIQAQDPDSSTNEKLAYRITSGNPQNFFVINPKTGLITTTSRKLDREQQAEHFLEVTVSDGGTSPKQSSVWVVVQVLDENDNKPQFPEKVYQIKLPERDRKKRGEPIYRAFAFDKDEGPNAEISYSIVDGNDDGKFFIDPKTGMVSSRKQFTAGSYDILTIKAVDNGRPQKSSTARLHIEWIKKPTPSPVPLTFDEPFYNFTVMESDKVTEIVGVVSVQPSNIPLWFDIVGGKHAREMFYILQTACGQNCSTEGGNYDSSFDAEKGVGTIVIAKPLDAEQRSIYNMTVEVTDGTNVATTQVFIKVLDNNDNGPEFSQPSYDVTISEDILPDTEILQIEAIDRDEKHKLSYTIHSSIDAISMRKFRIDPSAGVLYTAERLDHEAQDKHILNVMVRDQEFPYRRNLARVIINVEDSNDHSPYFTSPLYEASVYESAAVGSAVLQVTALDKDKGENAELVYTIEAGNTGNTFKIEPVLGIITLLKEPDLTTMGQFVLSVKVADQGSPPLSATAIVRISVTMADNSHPKFTLKEYQAEVNENVDIGTSVISLSAISQSTLVYEIKDGNVDGLFTINPYSGVITSQKALDYEHASFYQLTVQATNMAGMASNATVNIQIVDENDNPPVFLFSQYSGSISEAAPINSIVRSTNNSPLVIRATDADSNQNALLVYQIVESTAKKYFTVDSSTGAIRTIANLDHETIAHFHFHVHVRDSGNPQLTAESPVEVTIEVTDVNDNPPVFSQAVFETVLLLPTYVGVEVLKVKATDPDSEIPPELTYSLIEGNMDHFLIDSNTGVLTIKNNSLSKDHYMLIVRVSDGKFYSTAMVTIMVKEAMDSGLHFTQNFYSTSISENTTNITKIAVVNAVGNRLNEPLKYSILNPGNKFKIKSTSGVIQTTGISFDREEQELYELVVEASRELDHLRVARVVVRVYIEDINDNAPVFVGLPYYAAVQVDAEPGTLIYRVTAIDKDKDENGDVSYLLKEDYGHFEIDRGTGSVTLKEAFNSDLSNIEYLVVILAKDGGNPSLSASVELPITIVNKAMPVFDKPFYTASVNEDVEIHTPILSINATSPEGQGIIYIIVEGDPHNQFNIDFDTGVLSVISPLDYEINSLFKLMVRASDALTGARAEVTVDLVINDVNDNPPVFDQSAYNATLSEASLIGTPVLQVVATDADSDNNKIVQYQIVQDTFNSTDYFHIDSTSGLILTARMLDHELIQQCSLKVRATDNGFPPLSSEVLVSISITDMNDNPPVFNQLIYESYVSELAPRGHFVTCVQASDADSSDFDRLEYSILSGNDRTSFIMDSKSGVITLSNHRKQRMEPMYSLNVSVSDGLFTSTAQVHIQILGANLYSPVFSQSVYVAEVRENAAPGTKVLHVKATDGDSGVYGQISYSIINDFAKDRFLIDSNGQILTTERLDRENLLESDIGIFLRALDGGGRTTFCTVRVIVVDENDNAPQFMTVEYRASVKADVGKGYLVTQVQAVDPDDGANSRITYSLYSEASVSVADLLEIDPDNGWMVTKGSFNQLKNTVLSFFVKAVDGGIPVKHSLIPVYIHVLPPETILPSFSQPQYSFTLAEDTLIGSTIDIVHIVPNQGALYSTVNGELTENNKDGIFIIEQDTGLIKLDKRLDHETNSAFHFKVAATIQLDKVDIVLTVDVEVKVLDVNDNKPMFETASYDAIIMEGMPIGTKLMQVKAVDADSSANGQVTYTLAVESELEKITEAFTIDSNSGWISTLKDLDHEKDPTFTFAVVASDLGETLSLSSTTLVSVAVTDINDNAPVFEHEVYRGSVKESDPPGEVVAVLSTWDEDTSDVNRQVSYHITGGNPKGKFALGLVQNEWKVYVKRPLDREEQDVYYLNITATDGLFVTQAAVEVTVTDVNDNSPVCEQVAYTALFPEDIPSNKVILKISAKDADIGSNGDIRYSLYGPGNNKFFLDPENGELKSLAPLDREKIPVYNLVARATDGGGRFCQSEIHLILEDVNDNPPVFSSDHYTACVYENTATKALLTRVQATDPDVGVNRKVTYSLADSADGYFSVDRSSGIIILEHPLDRELQSSYNISVKASDQSIVLTLSSFATVTITVLDINDNPPVFERRDYLVTVPEDTSPGTEVLSVFATSQDIGTNAEITYLIRSGNEKGKFNINSKTGAISISESLDYESCKDFYLVVEAKDGGTPALSAVTTVNINVTDVNDNAPKFSQVVYSAVISEDAAIGDSVIMLIAEDLDSPSNGQIHFSIVSGDQDNEFSVDPGSGLVKVKKKLDRERISGYSLVIQARDSGTPPLSSSVTVNVDISDVNDNSPVFTPANYTAVIQENKPVGTSILQLVVTDKDSFHNGPPFTFTILTGNEEEEFTLDPNGVLRSAVIFKHMVATEYVLCVQAKDSGKPQQVSHTYIQVRVIEESIHKPTAIPLEIFIVTMEDDFPGGVIGKIHATDQDVYDVLTYTLKSEQKSLFKVNNHDGKIIALGGLDNGKYILNVSVSDGRFQVPIDVVVQVEQLLQEMLQNTVTIRFDNVSPEDFVGLHMHGFRRTLRNAVLSQKQDSLHIISIQPVAGSNQLDMLFAVQMHSGGFYKPAFLIQKLTNARRHLENVIRISAILEKNCSGLDCQEQHCEQSLSIDSHSLMTYSTARISFVCPRFYRNVRCMCNGGLCPGSNDPCLEKPCPGDMQCVGYEANRRPFICQCPPGKLGECSGHTSLSFAGNSYIKYRVSENSKKEEFKLALRLRTLQSNGIIMYTRANPCIILKIVDGKLWFQLDCGTGPGILGISGRAVNDGSWHSVFLELNRNFTSLSLDDSYVERRKAPLYFQTLSTDSSVYFGAQVQVDNVRSLTDKRTTQVLSGFQGCLDSVVLNNNELPLQNKRSSFAEVVGLTELKLGCVLYPDACERHPCQNGGTCTSVPSGGYQCNCLSQFTGRNCESEITACFPNPCRNGGSCDPIGNAFICNCKNGLTGVTCEEDINECEREECENGGSCVNVFGSFLCNCTPGYVGQYCGLRPVVVPNIQAGHSYVGKEELIGIAVVLFVIFVLIVLFIIFRKKVFRKNYSRNNITLVQDPATAALLNKSNGIQFKNIRNSGDSRNIYQEVGPPQVPVRPMAYTPCFQSDSRNNLDKIVDGLGVEHQEMTTFHPESPRILTARRGVVVCSVAPNLPAVSPCRSDCDSIRKSTWDAGTESKGVDDAEEVTCFAGSNKGSNSEVQSLSSFQSDSGDDNASIVTVIQLVNNVVDTIENEVSVMDQGQNYNRAYHWDTSDWMPSARLSDIEEVPNFEAADGGSAHHGSTRELETDYYLGGYDIDSDYPPPHEEEFLSQDQLPPPLPEDYPDQYETLPPSQPVSMANTLSPDCRRRPHFHPSQYLPPHQFPHETDTTGAQTGNEFSTFAVGPSQNTENVSAGKMPLTLHNSLDASSSDVSASCGFDDSEVAMSDFESVEELKLENVHIPFVETQHQTQV", "length": 4612 }, "evidence": [ { "id": "Q8TDW7", "url": "https://omabrowser.org/oma/group/Q8TDW7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1MC84-1", "protein_name": "Protocadherin Fat 3", "gene_name": "FAT3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDLTMGYCVGTRPPSCLILLLLKLLATLSQGLPGTGPLGFHFTHSIYNATVYENSAARTYVNSQSRMGITLIDLSWDIKYRIVSGDEEGFFKAEEVIIADFCFLRIRTKGGNSAILNREIQDNYLLIVKGSVRGEDLEAWTKVSIQVLDMNDLRPLFSPTTYSVTIAENTALRTSVAQVTATDADIGSNGEFYYYFKNKVELFSVHPTSGVISLSGRLNYDEKSRYDLEILAVDRGMKLYGNNGVSSTAKLYVHVERVNEHAPALHVVTHIPFSLDTEPVYAVVTADDLDEGANGEIESVSIVAGDPLDQFFLAKEGKWVNEYRVKEKKPVDWESFPYGYNLTLQAKDKGSPQKFSAVKIVHIANPKRDTVPIRFEKDAYEVSISEFSPPGVVVAIVKLSPEPLDVEYRLSPGEDAQYFKINPQSGLIVTAQPLNTIKKEVYRLGVTNKEGDLKTQVTISIEDANDHTPEFQQLLYEAFVNESVPVGTSVLTVSASDKDKGENGYITYSIASLNVLPFAINQFTGVISTTEDLDFESSPETYRFIVRASDWGSPYRHESEVNVTIRVGNVNDNSPLFEKVACQGVISYDFPVGGHITAVSAIDIDELELVKYKIISGNELGFFYLNPDSGVLQLKKSLMNSGIKNGNFALRITATDGENLADPMSVNISVLHGKVSSKSFSCRETRVAQKLAEKLLIKAKANGKLNLEDGFLDFYSVNRQGPHFDKSFPSDVAVKENLPVGANILKIKAYDADSGFNGKVLFTISDGNMDSCFNIDMETGQLQVLMPMDREHRDLYLLNITIYDLGNPQKSSWRLLTINVEDANDNSPIFLQDSYSVNILESSSIGTEIIQVEARDKDLGSNGEVTYSVLTDTQQFAINSSTGIVYIADQLDRESKANYSLKIEARDKAESGQQLFSVVTLKVFLDDVNDCSPAFIPSSYSVKVLEDLPVGTVIAWLETHDPDLGLGGQVRYSLVNDYNGRFEIDKASGAIRLSRELDYEKQQFYNLTVRAKDKGRPVSLSSVSFVEVEVVDVNENLHTPYFPDFAVVGSVKENSRIGTSVLQVTAHDEDSGRDGEIQYSIRDGSGLGRFNIDDESGVISTADILDRETTGSYWLTVYATDRGVVPLYSTIEVYIEIEDVNDNAPLTSEPIYYPVVMENSPKDVSVIQIQAEDPDSSSSEKLTYRITSGNPQNFFAINVKTGLITTTSRKLDREQQAEHFLEVTVTDGGFSPKQSTIWVVVQVLDENDNKPQFPEKVYQIKLPERDRKKRGEPIYRAFAFDRDEGPNAEISYSIVDGNDDGRFFIDPKTGMVSSRKQFTAGSYDILTIKAVDNGRPQKSSTARLHIEWIKKPPPSPVPLTFDEPFYNFTVMENDRVTEIVGVVSVQPANTLLWFDIVGGNFDSSFDAEKGVGTIVIAKPLDAEQRSIYNMSVEVTDGTNVAVTQVFIKVLDNNDNGPEFSQPNYDVTISEDVLPDTEILQIEATDRDEKHKLSYTVHSSIDSISMRKFRIDPSTGVLYTAERLDHEAQDKHILHIMVRDQEFPYRRNLARVIVNVEDANDHSPYFTNPLYEASVFESAALGSAVLQVTALDKDKGENAELMYTIEAGNTGNTFKIEPVLGIITVSKEPDMTTMGQFVLSVKVTDQGSPPMSATAIVRISVTMSDNSNPRFTHKDYQAEVNENVDVGTSVILISAISQSTLIYEVKDGNVDGIFTINPYSGVITTRKALDYERTSSYQLIVQATNMAGMASNVTVNIQIVDENDNAPVFLFSQYSGSLSEAAPINSIVRSLDNSPLVIRATDADSNRNALLVYQIVESTAKKFFTVDSSTGAIRTIASLDHEAIAHFHFHVHVRDSGSPQLTAESPVEVNIEVTDVNDNPPVFTQAVFETILLLPTYVGVEVLKVSAVDPDSEIPPELTYSLMEGSLDHFLIDSNSGVLTVKNNNLSKDHYMLIVKVSDGKFYSTSMVTILVKEAMDSGLHFTQNFYSTSISENNTNITKVAIVNAVGNRLNEPLKYSILNPGNKFKIKSTSGVIQTTGVPFDREEQELYELVVEASRELDHLRVARVVVRVSIEDINDNSPVFVGLPYYAAVQVDAEPGTLIYRVTAIDKDKGANGEVTYVLQDDYGHFEINPNSGNVILKEAFNSDLSNIEYGVTILARDGGKPSLSTSVELPITIVNKAMPVFDKPFYTASVNEDIAMDTPILSINATSPEGQGIIYIIIDGDLYKQFNIDFDTGVLKVISPLDYEMTSVYKLTVRASDALTGARAEVTIDLLVNDVNDNPPIFGQPTYNTTLSEASLIGTPVLQVVSTDADSGNNKMVHYQIVQDTYNSTDYFHIDSASGLILTARMLDHESVQHCTLKVRATDNGFPSLSSEVLVHIYISDVNDNPPVFNQLIYESYVSELAPRGHFVTCVQASDADSSDFDRLEYSILSGNDRTSFLMDSKSGIITLSNHRKQRMEPLYSLNVSVSDGLFTSTAQVHIRVLGANLYSPAFSQSTYVAEVRENAAAGTKVIHVRATDGDPGMYGQISYAIINDFAKDRFLIDGNGQVTTTERLDRENPLEGDISIFLRALDGGGRTTFCTVRVIVVDENDNAPQFLTVEYRASVRADVGRGHLVTQVQAMDPDDGANARITYSLYSEASVSVADLLEIDPDNGWMVTKGHFNQLKNTVLSFFVKAVDGGIPVKHSLIPVYIHVLPPETSVPSFTQSQYSFTVSEDTAIGSTVDTLRILPTQKVTFSTVNGERLENNKGNVFIIEQETGTIKLDKRLDHEVSPAFHFKVAATMPLDKVDAVFTVDVDVKVLDLNDNKPVFETSNYETIIMEGMPVGTKLTQVRAMDVDWGANGQVTYSLHSDSQPEKVMEAFSIDSNTGWISTLKDLDHETDPMFTFSVVASDLGEAFSLSSTALVSVRVTDINDNTPVFAHEVYRGNVKESDPPGEVVAVLSTWDRDTSDINRQVSYHITGGNPRGRFALGLVQSEWKVYVKRHLDREEQDIYFLNITATDGLFVTQAMVEVTVSDVNDNSPVCDQVAYTALLPEDIPSNKIILKVSAKDADIGPNGDIRYSLYGPGNNEFFLDPESGELKTLAPLDRERVPAYSLVARATDGGGRFCQSDLRLTLEDVNDNPPVFSSDHYNACVYENTATKALLTRVQAVDPDVGVNRKVVYSLADSANGFFSVDSSSGIVVLERPLDREQQSSYTLRVQATDQSPGRALSSLATISITVLDVNDNPPVFERRDYLVSVPEDTSPGTQVLAVFATSKDIGTNAEITYLIRSGNEQGKFRINPKTGGISVSEALDYELCRKFYLMVEAKDGGTPALSAVTTVGINLTDVNDNPPEFSQDVYSAVISEDALVGDSVILLIAEDADSQPNGQIRFSIVNGDRDNEFAVDPVLGLVKVKKKLDRERVSGYSLLVQAVDSGMPAMSSTATVNIDISDVNDNSPVFTPANATAVIQENKPVGTSVLQLMVTDKDSFHNGPPFSFSILSGNEEEAFVLDSDGILRSAVVFQHTESPEYVLCVQAKDSGKPQQVSHSYVRVRVIEESIHKPTAIPLEIFIVTMEDDFPGGVIGKIHATDQDMYDVLTFALKSEQKSLFKVNSHDGKIIALGGLDSGKYVLNVSVSDGRFQVPIDVVVHVEQLVQEMLQNTVTIRFENVSPEDFVGLHMHGFRRTLRNAVLTQKQDSLHIISIQPVAGTSELDMLFAVETHSSEFYKPAYLIQKLSNARRHLENAMRISAILEKNCSGLDCQEQHCEQGLSLDSHALMTYSTARISFVCPRFYRNVRCTCDGGLCPGANDPCVEKPCPGDMQCVGYEASRRPFLCQCPPGKLGECSGHTSLSFAGNSYIKYRLSENSKEEDFKLALRLRTLQSNGIIMYTRANPCIILKIVDGRLWFQLDCGSGPGILGISGRAVNDGSWHSVFLELNRNFTSLALDDSYVERRRAPLYFQTLGTDSAIYFGALVQADSIRSLTDARVTQVLSGFQGCLDSVVLNNNELPLQNKRSSFAEVVGLTELKLGCVLYPDACERGPCQHGGSCAGLASGGYQCTCLSQFTGRNCESEITACFPNPCRNGGSCDPIGNTFICSCKAGLTGVTCEEDVNECEREECENGGACVNVFGSFVCNCTPGYVGQYCGLRPVVVPNIQAGHAYVGREELIGIAAVLLVIVALIVLFVVFRKKVFRKSYSRNNITLVQDPATAALLRKSNGVPFRSLRAGDGRHAYQEAGPPQVPVRPMAYTPCFQGDSRSNLDKIGDGLGGEPQEMTTFHPESPRILTARRGVVVCSVAPNLPAVSPCRSDCDSIRKNGWDAGTENKGVDDPGEVTCFAGSNKGSNSEVQSLSSFQSDSGDDNAYHWDTSDWMPGARLSDIEEVPTYESQEGAAPPGSARGLESDYYLGGYDVDSEYPPPHDDDFLGQDPLPPPLPEDFADQYDGLPPARPGSLAGTLSPGCRRRPQFHPSQYLPPHPFPHETDVGGPPAAGEFSTFAVSVNPGAEAAAGPADGVALSLHNSRGPSSSDVSASCGFDDSEVAVSDYESVGELSLASLHIPFLETQQQTQV", "length": 4555 }, "evidence": [ { "id": "Q8TDW7", "url": "https://omabrowser.org/oma/group/Q8TDW7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O88277-1", "protein_name": "Protocadherin Fat 2", "gene_name": "Fat2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLVLLGLAILLLHRAACEKSLEETIPPLSWRFTHSLYNATIYENSAPKTYVESPVKMGMYLAEPHWVVKYRIISGDAAGVFKTEEHVVGNFCFLRIRTKSSNTALLNREVRDSYTLIVQASDKSLEFEALTQVVVHILDQNDLKPLFSPPSYRVTISEDRPLKSPICKVTATDADLGQNAEFYYAFNARSEVFAIHPTSGVVTVAGKLNVTRRGKYELQVLAVDRMRKISEGNGFGNLASLVIRVEPVHRKPPAINLVVLNPPEGDEGDIYAIVTVDTNGSGAEVDSLEVVGGDPGKYFKVLRSYAQGNEFNLVAVRDINWAEHPHGFNISLQTHSWSRFPPHSIIRAFHLPSWKLANLRFEKAVYRVKLSEFSPPGSRVALVKVTTALPNLRYSLKPSSRNTAFKLNARTGLITTTKLVDFHEQNQYQLHVKTSLGQATTTVIIDIVDCNNHAPVFNRSSYEGTLDENIPPGTSVLTVTATDQDHGDNGHITYSIAGPKAVPFSIDPLLGVISTTKPMDYELMKRIYTFRVRASDWGSPFRQEKEVSVSLRLKNLNDNQPMFEEVNCTVSLRQDVPVGKSIMAVSAIDMDELQNLKYEIVSGNEQDYFHLNHFSGVISLKRSFMNLTAVRPTIYSLKITASDGKNYASPTTLKVTVVKDPHSEVPVQCDKTGVLTHITKTILQSAGLQSQELGEEEFTSLSNYQINHHSPQFEDHFPQSIDILEQVPINTPLARLAATDPDTGFHGKLVYVISDGNEEGCFDIELETGLLMVAAALDYETTSFYVLNVTVYDLGTPPKSSWKLLTVTVKDWNDNPPRFPPGGYQLTISEDTEVGTTIAELKTEDADSEDNRRVRYTLLTPTEKFSLHPFTGELVVTGHLDRESESQYILKAEARDQPTKGHQLFSVTDLIVTLEDINDNPPQCITEHRRLKVPEDMPLGTVLTFLDASDPDLGPAGEVKYILVEDAHGTFQVHPMTGALSLEKELDFERRAGYNLSFWASDSGKPLSRRTLCHVEVLVMDVNENLHSPHFSSFVYQGQVQENSPAGTPVMVVTAQDDDSGLDGELQYFLRAGTGLETFSINQDTGMLETLAPLDREFTPYYWLTVLAVDRGSVPLSAVTEVYIEVTDINDNIPSMSRPVFYPSVLEDAPLGTSVLQLEAWDPDSSSQGKLTFNLTSGNHLGHFIVHPFTGLLTTAKQLDRENKDEYVLEVTVQDNGDPSLRSTSRVVVCILDVNDNPPMFSHKLFNVRLSERLSPLSPEPVYRLVASDPDEGLNGSVTYSIEESDEESFRIDPVTGVVSSSSTFAAGEYNILTIKATDSGQPALSTSVRLHIEWIPQPRPSSIPLSFDESYYSFTVMETDPVNHMVGVISVEGRPGLFWFHISDGDKDMDFDIEKTTGSIVIARPLDTRRKSSYNLTVEVTDGFHTIATQVHIFMIANINHHRPQFLQDHYEIRVPQDTLPGVELLRVQATDQDHGKGLIYTILSSQDPGSANLFQLDPSSGVLVTVGTLELHSGPSQHILTVMVRDQEMPIKRNFVWVTIHVEDGNLHSPHFTQLRYEANVPDTTAPGTELLQVRAVDADRGANAEIHYSFLKGNSDGFFNIDSLLGIITVAQRLYHVHLTRHALTVKAEDQGSPRRHDLALVVIHVHPSDSSAPVFSKDEYFIEIPESVPIGSPILLLSAGSSSEVTYELREGNKDSVFSMNSYSGLISTQKRLDHEKVPSYRLRIRGSNMAGVFTEVVALVYIIDENDNPPAFGKPTFLGHISEAAPLHSLILGEDNSPLVVRASDSDREANSLLVYKILEPEALKFFKIDPSMGTLTTTSELDFEDTPLFQFNIYVHDQGTPILFAPRSAKVIIHVRDVNDSPPRFSEQIYEVAVVEPIHPGMGLLTVQAEDNDSRVTYSIKTSNADEAVTIHPTTGQISVVNPATLRLFQKFSIRASDGLYHDTAVVKISLTQVLDKSLQFDQDVYRARVTENTPHRKALVILGVHGNHLNDTLSYFLLNGTDLFHMIESAGVLQTRGGTFDREQQDTHEVAVEVRDNRVPQRVAQALVRVSVEDVNDNIPEFQHLPYYTVIQDGTEPGDVLFQVSATDKDLGANGSVTYGFAEDYAYFRIDPYVGDISLKKPFDYQALNKYHLRVIARDSGIPPLQTEVEVHVTVRNKSNPLFQSPYYKVKVPENITLYTPILHTQARSPEGLRLIYNIVEEEPLMLFTTDFKTGVLTVTGPLDYESKNKHVFTVRATDTALGSFSEATVEVLVEDINDNPPTFSQLVYTTSVSEGSPAQTPVIQLLASDQDSGQNQDVSYQIVEDGSDVSKFFRINGSTGEIFTIQELDYETHQHFRVKVRAMDKGDPPLTGETLVVVNVSDINDNPPKFREPQYEANVSELATCGHLVLKVQALDPDIGDTSRLEYLILSGNQDRHFSINSTSGIISMFNLCKKQLDSSYNLRVGASDGVFRATVPVYINTTNANKYSPEFQQNVYEAELAENAKVGTKVIELLAIDKDSGPYGTVDYTIINKLAGERFFINPRGQITTLQKLDRENSTERVIAIKVMARDGGGKVAFCTVKIILTDENDNAPQFKASGYTVSIPSNVSRDSPIIQVLAYDADEGRNADVTYSVDSTEDLAEEIIEVNPTTGVVKVKESLVGLENRAVDFNIKAQDGGPPHWDSLVPVRLQVVPNEIPLPKFSEPLYTFSAPEDLPEGSEIGSVKAVAAQDPIIYSLVQGTTPESNSDDVFSLDQDTGVLKVRKAMDHESTKWYQIDLMAHCPHEDTDLVSLVSVSIQVEDVNDNRPVFEADPYKAFLTENMPGGTTVIQVTANDQDTGSDGQVSYRLSVEPGSNIHELFAVDSESGWITTLQELDCETQQTYRFYVVAFDHGQTIQLSSQALVEVSITDENDNPPRFASEDYRGSVVENNEPGELVATLKTLDADVSDQNRQVTCYITEGDPLGQFSISQVGDEWRISSRKTLDREHIAKYLLRVTASDGKFQASVPVEVFVVDINDNSPQCSQLLYTGKVREDVTPGHFILKVSAIDVDMDTNAQITYSLHGPGAQEFKLDPHTGELTTLTVLDRERKDVYNLVAKATDGGGQSCQAEVTLHIEDVNDNAPRFFPSHCDVAVFDNTTVKTPVAVVFARDPDQGANAQVVYSLTDSADGQFSIDATSGVIRLEKPLQVRASSAVELTVRASDLGTPIPLSTLGTVTVSVVGLEDYLPIFLNAEHSTQVPEDAPIDMEVLHLATLTRPGSEKTGYHITGGNEQGKFRLDAHTGILYVNGSLDFETNPKYFLSIECSRKSSSSLSDVTTIVINVTDVNEHHPRFTHDLYTVRVLENAVVGDVILTVSASDDDGPVNSAITYSLVGGNQLGHFTINPKKGKLQVAKALDWEQTPSYSLRLRATDSGQPPLHEDTEVAVEVVDVNDNPPRFFQLNYSTSVQENSPIGIKVLQLILDDPDSPQNGPPYFFRITEGNTGSVFRVTPDGWLVTAASLSKKAREWYQLHIEVSDSGLPPLSSSTLVRVQVTEQSRYPPSTLPLEISITKGEEEFQGGMIGKIHATDRDPQDTLTYSLEQEGGLDRYFTVGASDGKIIASQGLPHGRYSFNVTVSDGTFTTTTGVHVHVWHMEPEVPQQAVWLGFHQLTPEELVSDHWRNLQRFLSNLLDVKRANIHLASLQPAEVTAGVDVLLVFERHSGTSYDLQELASAIAHSVREIEHSVGIRMRSALPVVPCQGQSCQDQTCQETVSLEPRVGPSYSTARLSILTPRHHLGRNCSCNGTTLRFSGQSYVQYRPLEAQNWQIHFYLKTLQPWALLMFTNETASISLKLANGFSHLEYHCPGGFYGNLSSRYPVNDGQWHSMLLEERDTSVHLLVDITDNASLVIPEECQGLRTERQLLLGGLVPSNPSSNVSLGFEGCLDAVVVNGERLELLGREKKMEGRLETWALSQCCWPGTACSQSPCLNGGSCSPALGSGYLCRCPPPFSGRNCELGRENCTSAPCQEGGTCVSSPEGTSCNCPHPYTGDRCEMEARGCSGGHCLITPEIKRGDWGQQEFLVITVALPLVIIATVGLLLYCRRRKSHKPVTMEDPDLLARSIGVDTQASPAIELDPLNTSSCNNLNQPEPSKTSVPNELVTFGPSSKQRPMVCSVPPRLPPAAVSSHPGHEPIIKRTWSGEELVYPSGAAVWPPTYSRKKHWEYPHPETMQGTLPPSPRRHVGPAVMPDPTGLYGGFPFPLELENKRAPLPPRYSNQNLEDLMPPRPPSPREHLLAPCLNEYTAISYYHSQFRQGGGGPCLAEGGYKGVSMRLSRAGPSYADCEVNGGPATGRSQPRAPPNYEGSDMVESDYGSCEEVMF", "length": 4351 }, "evidence": [ { "id": "FB:FBgn0261574", "url": "https://alliancegenome.org/gene/FB:FBgn0261574#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q14517-1", "protein_name": "Protocadherin Fat 1", "gene_name": "FAT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGRHLALLLLLLLLFQHFGDSDGSQRLEQTPLQFTHLEYNVTVQENSAAKTYVGHPVKMGVYITHPAWEVRYKIVSGDSENLFKAEEYILGDFCFLRIRTKGGNTAILNREVKDHYTLIVKALEKNTNVEARTKVRVQVLDTNDLRPLFSPTSYSVSLPENTAIRTSIARVSATDADIGTNGEFYYSFKDRTDMFAIHPTSGVIVLTGRLDYLETKLYEMEILAADRGMKLYGSSGISSMAKLTVHIEQANECAPVITAVTLSPSELDRDPAYAIVTVDDCDQGANGDIASLSIVAGDLLQQFRTVRSFPGSKEYKVKAIGGIDWDSHPFGYNLTLQAKDKGTPPQFSSVKVIHVTSPQFKAGPVKFEKDVYRAEISEFAPPNTPVVMVKAIPAYSHLRYVFKSTPGKAKFSLNYNTGLISILEPVKRQQAAHFELEVTTSDRKASTKVLVKVLGANSNPPEFTQTAYKAAFDENVPIGTTVMSLSAVDPDEGENGYVTYSIANLNHVPFAIDHFTGAVSTSENLDYELMPRVYTLRIRASDWGLPYRREVEVLATITLNNLNDNTPLFEKINCEGTIPRDLGVGEQITTVSAIDADELQLVQYQIEAGNELDFFSLNPNSGVLSLKRSLMDGLGAKVSFHSLRITATDGENFATPLYINITVAASHKLVNLQCEETGVAKMLAEKLLQANKLHNQGEVEDIFFDSHSVNAHIPQFRSTLPTGIQVKENQPVGSSVIFMNSTDLDTGFNGKLVYAVSGGNEDSCFMIDMETGMLKILSPLDRETTDKYTLNITVYDLGIPQKAAWRLLHVVVVDANDNPPEFLQESYFVEVSEDKEVHSEIIQVEATDKDLGPNGHVTYSIVTDTDTFSIDSVTGVVNIARPLDRELQHEHSLKIEARDQAREEPQLFSTVVVKVSLEDVNDNPPTFIPPNYRVKVREDLPEGTVIMWLEAHDPDLGQSGQVRYSLLDHGEGNFDVDKLSGAVRIVQQLDFEKKQVYNLTVRAKDKGKPVSLSSTCYVEVEVVDVNENLHPPVFSSFVEKGTVKEDAPVGSLVMTVSAHDEDARRDGEIRYSIRDGSGVGVFKIGEETGVIETSDRLDRESTSHYWLTVFATDQGVVPLSSFIEIYIEVEDVNDNAPQTSEPVYYPEIMENSPKDVSVVQIEAFDPDSSSNDKLMYKITSGNPQGFFSIHPKTGLITTTSRKLDREQQDEHILEVTVTDNGSPPKSTIARVIVKILDENDNKPQFLQKFYKIRLPEREKPDRERNARREPLYHVIATDKDEGPNAEISYSIEDGNEHGKFFIEPKTGVVSSKRFSAAGEYDILSIKAVDNGRPQKSSTTRLHIEWISKPKPSLEPISFEESFFTFTVMESDPVAHMIGVISVEPPGIPLWFDITGGNYDSHFDVDKGTGTIIVAKPLDAEQKSNYNLTVEATDGTTTILTQVFIKVIDTNDHRPQFSTSKYEVVIPEDTAPETEILQISAVDQDEKNKLIYTLQSSRDPLSLKKFRLDPATGSLYTSEKLDHEAVHQHTLTVMVRDQDVPVKRNFARIVVNVSDTNDHAPWFTASSYKGRVYESAAVGSVVLQVTALDKDKGKNAEVLYSIESGNIGNSFMIDPVLGSIKTAKELDRSNQAEYDLMVKATDKGSPPMSEITSVRIFVTIADNASPKFTSKEYSVELSETVSIGSFVGMVTAHSQSSVVYEIKDGNTGDAFDINPHSGTIITQKALDFETLPIYTLIIQGTNMAGLSTNTTVLVHLQDENDNAPVFMQAEYTGLISESASINSVVLTDRNVPLVIRAADADKDSNALLVYHIVEPSVHTYFAIDSSTGAIHTVLSLDYEETSIFHFTVQVHDMGTPRLFAEYAANVTVHVIDINDCPPVFAKPLYEASLLLPTYKGVKVITVNATDADSSAFSQLIYSITEGNIGEKFSMDYKTGALTVQNTTQLRSRYELTVRASDGRFAGLTSVKINVKESKESHLKFTQDVYSAVVKENSTEAETLAVITAIGNPINEPLFYHILNPDRRFKISRTSGVLSTTGTPFDREQQEAFDVVVEVTEEHKPSAVAHVVVKVIVEDQNDNAPVFVNLPYYAVVKVDTEVGHVIRYVTAVDRDSGRNGEVHYYLKEHHEHFQIGPLGEISLKKQFELDTLNKEYLVTVVAKDGGNPAFSAEVIVPITVMNKAMPVFEKPFYSAEIAESIQVHSPVVHVQANSPEGLKVFYSITDGDPFSQFTINFNTGVINVIAPLDFEAHPAYKLSIRATDSLTGAHAEVFVDIIVDDINDNPPVFAQQSYAVTLSEASVIGTSVVQVRATDSDSEPNRGISYQMFGNHSKSHDHFHVDSSTGLISLLRTLDYEQSRQHTIFVRAVDGGMPTLSSDVIVTVDVTDLNDNPPLFEQQIYEARISEHAPHGHFVTCVKAYDADSSDIDKLQYSILSGNDHKHFVIDSATGIITLSNLHRHALKPFYSLNLSVSDGVFRSSTQVHVTVIGGNLHSPAFLQNEYEVELAENAPLHTLVMEVKTTDGDSGIYGHVTYHIVNDFAKDRFYINERGQIFTLEKLDRETPAEKVISVRLMAKDAGGKVAFCTVNVILTDDNDNAPQFRATKYEVNIGSSAAKGTSVVKVLASDADEGSNADITYAIEADSESVKENLEINKLSGVITTKESLIGLENEFFTFFVRAVDNGSPSKESVVLVYVKILPPEMQLPKFSEPFYTFTVSEDVPIGTEIDLIRAEHSGTVLYSLVKGNTPESNRDESFVIDRQSGRLKLEKSLDHETTKWYQFSILARCTQDDHEMVASVDVSIQVKDANDNSPVFESSPYEAFIVENLPGGSRVIQIRASDADSGTNGQVMYSLDQSQSVEVIESFAINMETGWITTLKELDHEKRDNYQIKVVASDHGEKIQLSSTAIVDVTVTDVNDSPPRFTAEIYKGTVSEDDPQGGVIAILSTTDADSEEINRQVTYFITGGDPLGQFAVETIQNEWKVYVKKPLDREKRDNYLLTITATDGTFSSKAIVEVKVLDANDNSPVCEKTLYSDTIPEDVLPGKLIMQISATDADIRSNAEITYTLLGSGAEKFKLNPDTGELKTSTPLDREEQAVYHLLVRATDGGGRFCQASIVLTLEDVNDNAPEFSADPYAITVFENTEPGTLLTRVQATDADAGLNRKILYSLIDSADGQFSINELSGIIQLEKPLDRELQAVYTLSLKAVDQGLPRRLTATGTVIVSVLDINDNPPVFEYREYGATVSEDILVGTEVLQVYAASRDIEANAEITYSIISGNEHGKFSIDSKTGAVFIIENLDYESSHEYYLTVEATDGGTPSLSDVATVNVNVTDINDNTPVFSQDTYTTVISEDAVLEQSVITVMADDADGPSNSHIHYSIIDGNQGSSFTIDPVRGEVKVTKLLDRETISGYTLTVQASDNGSPPRVNTTTVNIDVSDVNDNAPVFSRGNYSVIIQENKPVGFSVLQLVVTDEDSSHNGPPFFFTIVTGNDEKAFEVNPQGVLLTSSAIKRKEKDHYLLQVKVADNGKPQLSSLTYIDIRVIEESIYPPAILPLEIFITSSGEEYSGGVIGKIHATDQDVYDTLTYSLDPQMDNLFSVSSTGGKLIAHKKLDIGQYLLNVSVTDGKFTTVADITVHIRQVTQEMLNHTIAIRFANLTPEEFVGDYWRNFQRALRNILGVRRNDIQIVSLQSSEPHPHLDVLLFVEKPGSAQISTKQLLHKINSSVTDIEEIIGVRILNVFQKLCAGLDCPWKFCDEKVSVDESVMSTHSTARLSFVTPRHHRAAVCLCKEGRCPPVHHGCEDDPCPEGSECVSDPWEEKHTCVCPSGRFGQCPGSSSMTLTGNSYVKYRLTENENKLEMKLTMRLRTYSTHAVVMYARGTDYSILEIHHGRLQYKFDCGSGPGIVSVQSIQVNDGQWHAVALEVNGNYARLVLDQVHTASGTAPGTLKTLNLDNYVFFGGHIRQQGTRHGRSPQVGNGFRGCMDSIYLNGQELPLNSKPRSYAHIEESVDVSPGCFLTATEDCASNPCQNGGVCNPSPAGGYYCKCSALYIGTHCEISVNPCSSKPCLYGGTCVVDNGGFVCQCRGLYTGQRCQLSPYCKDEPCKNGGTCFDSLDGAVCQCDSGFRGERCQSDIDECSGNPCLHGALCENTHGSYHCNCSHEYRGRHCEDAAPNQYVSTPWNIGLAEGIGIVVFVAGIFLLVVVFVLCRKMISRKKKHQAEPKDKHLGPATAFLQRPYFDSKLNKNIYSDIPPQVPVRPISYTPSIPSDSRNNLDRNSFEGSAIPEHPEFSTFNPESVHGHRKAVAVCSVAPNLPPPPPSNSPSDSDSIQKPSWDFDYDTKVVDLDPCLSKKPLEEKPSQPYSARESLSEVQSLSSFQSESCDDNGYHWDTSDWMPSVPLPDIQEFPNYEVIDEQTPLYSADPNAIDTDYYPGGYDIESDFPPPPEDFPAADELPPLPPEFSNQFESIHPPRDMPAAGSLGSSSRNRQRFNLNQYLPNFYPLDMSEPQTKGTGENSTCREPHAPYPPGYQRHFEAPAVESMPMSVYASTASCSDVSACCEVESEVMMSDYESGDDGHFEEVTIPPLDSQQHTEV", "length": 4588 }, "evidence": [ { "id": "FB:FBgn0261574", "url": "https://alliancegenome.org/gene/FB:FBgn0261574#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5F226-1", "protein_name": "Protocadherin Fat 2", "gene_name": "Fat2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTLVLLGVAMVLLHRAACEKPLEETITPLTWRFTHSLYNATIYENSAPKTYVESPVKMGMYLAEPHWVVKYRIISGDAAGVFKTEEHVVGNFCFLRIRTKSSNTALLNREVRDSYTLVVQASDKSLEFEALTQVVVHILDQNDLKPLFSPPSYRFTISEDRPLKSPICKVTATDADLGQNAEFYYAFNARSEVFAIHPTSGVVTVAGKLNVTWRGKYELQVLAVDRMRKISEGNGFGNLAPLVIYVEPVHRKPPVITLVVLNPPEGDEGDIYATVTVDTNGSGAEVDSLEVVGGDPGKYFKVLKSYAQGNEFNLVAVRDINWAEHLHGFNISLQTHSRSRFPSRSIIRAFHLPPYTLANLRFEKAVYRVKLSEFSPPGSRVALVRVTTALPTLRYALKPSSGSTVFKLNARTGLITTTKPVDFHEQNQYQLHVKTSLGQATTTVIIDIVDCNNHAPVFNRSSYEGTLDENIPPGTSVLTVTATDQDHGDNGHITYSIAGPKAVPFSIDPYLGVISTTKSMDYELMKRIYTFRVRASDWGSPFRQEKEVSVSLRLKNLNDNQPMFEEVNCTVSLRQDAPVGKSIMAVSAIDMDELQNLKYEIVSGNEQDYFHLNHFSGVISLKRSFMNLTAVRPTVYSLKITASDGKNYASPTTLKVTVVKDPRSEVPVQCDKTGVLTHITKTILQSAGLQGQEMGEEDFTSLGNYQINHHAPQFEDHFPQSIDILEQVPVNTPLAHLAATDPDPGFHGRLVYVIADGNEEGCFDIELETGLLTVAAALDYETTSFYVLNVTVYDLGTPPKSSWKLLTVTVKDWNDKPPRFPPGGYQLTISEDTEVGTTVAELKTRDTDSEDNGRVRYTLLTPTEKFSLHPLTGELVVTGQLDRESEPQYILKAEARDQPTKGHQLFSVTDVIVTLEDINDNPPQCITEHSSLKVPEDMPLGTVLTFLDASDPDLGPAGEVKYILVDDVHGTFRVDPMTGALSLEKELDFERRAGYNLSFWASDSGRPLARRTLCHVEVLVMDVNENLHSPHFSSFVYQGQVQENSPAGTQVMVVTAQDDDSGLDGELQYFLRAGTGLEAFSINQDTGMLETLAPLDREFTPYYWLTVLAVDRGSVPLSAVTEVYIEVTDINDNIPSMSRPVFYPSVKEDAPLGTSVLQLEAWDPDFSSQGKLTFNLTSGNHMGHFIVHPFTGLLSTAKQLDRENKDEYVLEVTVQDNGDPPLRSTSRVVVCVLDVNDNSPMFSHKLFNVRLSERLSPLSPEPVYRLVASDPDEGLNGSITYSIEESDEESFRIDPVTGVVSSSSTFAAGEYNILTIKATDSGQPALSTSVRLHIEWIPQPRPSSIPLSFDESHYSFAVMETDPVNHMLGVISVEGRPGLFWFHISDGDKDMDFDIEKTTGSIVIARPLDTRRKSSYNLTVEVTDGFHTIATQVHILMIANINHHRPQFLQDHYDIRVPQDTLPGVELLRVQATDQDHGKGLIYTIHSSRDPGSANLFQLDPSSGVLVTVGTLDLHSGPSQHILTVMVRDQEMPIKRNFVWVTIHVEDGNLHSPHFTQPRYEANVPDTTTPGTELLQVRAVDADRGANAEVHYSFLKGNSEGFFNIDSLLGIITVAQRLDHVHLNRHALTVKAEDQGSPQRHDLAMVVVHVHPSDSSAPIFSKDEYFIEIPESVPIGSPILLISAASSSDVTYELREGNKNSVFSMNSYSGLISTQKRLDHEKVSSYQLKIRGSNMAGVFTEVVALVYIIDENDNAPAFLKSTFVGHISEAAPLHSLILGEDNSPLVIRASDSDQEANSLLVYKILEPEALKFFKIDPSMGTLTITSELDYETTPLFQFSIYVHDQGTPILFAPRSARVIIHVRDVNDSPPRFSEQIYEVAVVEPIHPGMELLTVQAEDNDSKVTYSIKTSNTDEAVTIHPITGQISVVNPAALRLFPKLNIRAFDGLYQDTAVVKISLTQALDKSLQFDQDIYRARVTENTPHSNVLVILGVHGNHLNDTLSYFLLNGTDLFHMVKSAGVLQTRGVTFDREQQDTHEVAVEVRDNRVPRRVAQALVRVSVEDVNDNIPEFQHLPYYTVIQDGTEPGDVLFQVSATDKDLGANGTVTYGFAEDYAYFRIDPYVGDISLKKPFDYQALNKYHLRVTARDAGTPPLQTEVEVHVTVRNKSNPLFQSPYYKVKVPENITLYTPILHTQARSPEGLRLIYNIVEEEPLMLFTTDFKTGVLTVTGPLDYESKNKHVFTVRATDTALGSFSEATVEVLVEDINDNPPTFSQLVYSTSVSEGSPAQTPVIQLLASDQDSGQNQDVSYQIVEDGSDVSKFFRINGSTGEMFTIQELDYEAHQHFRVKVRATDRGDPPLTGETLVVVNVSDINDNPPEFREPQYEANVSELATCGHLVLKVQALDPDIGDTSRLEYLILSGNQDRHFSINSTSGIISMFNLCKKQLDSSYNLRVGASDGVFQATVPVYINTTNANKYSPEFQQNVYEAELAENAKVGTKVIELLAIDKDSGPYGTVDYTIINKLAGERFFINPSGQITTLQKLDRENSTERVIAIKIMARDGGGKVAFCTVKIILTDENDNAPQFKASGYTVSIPSNVSRDSPIIQVLAYDADEGRNADVTYSVDSTEDLAEEIIEVNPTTGVVKVKESLVGLENKAVDFNIKAQDGGPPHWDSLVPVRLQVVPNEIPLPKFSEPLYTFSASEDLPEGSEIGSVKAVAAQDPIIYSLVQGTTPESNSDDVFSLDQDTGVLKVKKAMDHESTKWYQIDLMAHCPHEDTDLVSLVSVNIQVEDVNDNRPVFEADPYKAFLTENMPGGTTVIQVTANDQDTGSDGQVSYRLSVEPGSNIHQLFAVDSESGWITTLQELDCETQQTYRFYVVAFDHGQTIQLSSQALVEVSITDENDNPPRFASEDYRGSVVENNEPGELVATLKTLDADISEQNRQVTCYITEGDPLGQFSISQVGDEWRITSRKTLDREHIAKYLLRITASDGKFQASVPVEVFVLDINDNSPQCSQLLYTGKVREDVTPGHFILKVSAIDVDMDTNAQITYSLHGPGAQEFKLDPHTGELTTLSVLDRERKDVYNLVAKATDGGGQSCQAEVTLHIEDVNDNAPRFFPSHCAVAVFDNTTVKTPVAVVFARDPDQGVNAQVVYSLTDSADGQFSIDATSGVIRLEKPLQVRSSSAVELTVRASDLGTPIPLSTLGTVTVSIVGLEDYLPIFLNSEHSTQVPEDALIDMEVLYLATLTRPGSEKTGYHITGGNEQGKFRLDAHTGILYVNGSLDFETNPKYFLSIECSRKSSSSLSDVTTIVINVTDVNEHHPRFTHDLYTVRVLENAIVGDVILTVSASDDDGPVNSVITYSLVGGNQLGHFTIDPKKGKLQVAKALDWEQTPSYSLRIRATDSGQPPLHEDTEVAVEVVDVNDNPPRFFQLNYSTAVQENSPIGIKVLQLILDDPDSPQNGPPYFFRITEGNTGSVFRVTPDGWLVTAGSLSRRAQEWYQLHIEVSDSGLPPLSSSTLVRVHITEQSRYPPSTLPLEIFITKGEEEFQGGMVGKIHATDRDPQDTLTYSLDREGSLGKYFTVGASDGKIIASQGLPRGRYLFNVTVSDGTFTTTTGVHVHVWHMGQEAPQQAVWLGFHQLTPEELVSDHWRNLQRFLSNILDIKRANIHLASLQPAEVTAGVDVLLAFEGHSGTSYDLQELASAIAHSAKEMEHSVGIQMRSALPVVPCQGPSCQDQTCQETVSLEPRVGPSYSTARLSILTPRHHLGKNCSCNGTTWRFSGQSYMRYRPLEAQNWQIHFYLKTLQPWALLMFTNETASISLKLANGFLHLEYRCPGGFYGNLSSHRPVNDGQWHSMLLEERDTSVHLLVDITDNTSLVIPEECQGLRTERHLLLGGLVPSNPSSNVSLGFEGCLDAVVVNSERLELLGHRKKMAGYLETWALSQCCWPGTTCSQNPCLNGGSCSPALGSGYLCRCPPLFSGRNCELGRENCTSAPCQEGGTCVSSPEGTSCSCPHPYTGDRCEMEARGCSGGHCLITPEIKRGDWGQQEFLVIIVALPLLIIATVGLLLYCRRCKSHKPVAMEDPDLLARSIGVDTQASPAIELDPLNAGSCNDLNQLEPSKTSVPNELVTFGPSSKQRPMVCSVPPRLPPAVVSSHPGHEPIIKRTWSGEELVYPSGAAVWPPTYSRKEHWEYPHPEAMQGPLPPSPRRHVSPAVMPDPAGLYGGFPFPLELENKRAPLPPRYSNQNLEDLIPPRPPSPREHLLAPCLNEYTAISYYHSQFRQGGGGPCLAEGGYKGVSMRLSRAGPSYADCEVNGGPAPGRSQPRAPPNYEGSDMVESDYGSCEEVMF", "length": 4351 }, "evidence": [ { "id": "FB:FBgn0261574", "url": "https://alliancegenome.org/gene/FB:FBgn0261574#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BNA6-1", "protein_name": "Protocadherin Fat 3", "gene_name": "Fat3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVTMGHCMGTKPPSCIILLLLKLFATVSQGLPGTGPLGFHFTHSTYNATVYENSAARTYVNSQSRMGITLIDLSWDIKYRIVSGDEEGFFKAEEVIIADFCFLRIRTKGGNSAILNREIQDNYLLIIKGSVRGEDLEAWTKVNIQVLDMNDLRPLFSPTTYSVTIAESTPLRTSVAQVTATDADIGSNGEFYYYFKNKVDLFSVHPTSGVISLSGRLNYDEKNRYDLEILAVDRGMKLYGNNGVSSTAKLYVHIERINEHAPIIHVVSHTPFSLDKEPTYAVVTVDDLDEGANGEIESLSIVDGDPLEQFFLAKEGKWLNEYKVKERRQVDWESFSYGYNLTIQAKDKGSPQKFSELKTVHIANPRRDNTPVRFEKDVYEVSISEFSPPGVLVAIVKVSPEPLDVEYKLLPGKDSDYFKINPRSGLIVTAQPLNTVKKEVYKLEVSDKEGDAKAQVTIGIEDANDHTPEFQEALYETFVNESVRVGTNVLTVSASDKDKGENGYITYSIASLNLLPFAINQFTGVISTTEELDFESSPETYRFIVRASDWGSPYRHESEVNVTIRVGNVNDNSPLFEKVACQGVISYDFPVGGHITAISAIDIDELELVKYKIISGNELGFFYLNPDSGVLQLKKSLMNSGIKNGNFALRITATDGENFADPMAINISVLHGKVSSKSFSCRETRVAQKLAEKLLIKAKANGKLNLEDGFLDFYSINRQGPHFDKSFPSDVAVKEDMLVGTNILKIKAYDADSGFNGKVLFTISDGNTDSCFNIDMETGQLKVLMPMDREHTDLYVLNITIYDLGKPQKSSWRLLTVNVEDANDNNPVFLQDSYSVSILESSSIGTEIIQVEARDKDLGSNGEVMYSVLTDTHQFIINSSTGIVYIADQLDRESKANYSLKIEARDKAESGQQLFSVVTLKIFLDDVNDCSPAFIPSSYSVKVLEDLPVGTVIAWLETQDPDLGLGGQVRYSLVNDYNGRFEVDKASGAIRLSKELDYEKQQFYNLTVRAKDKGRPVSLSSVSFVEVEVVDVNENLHTPYFPDFAVVGSVKENSRIGTSVLQVTAHDEDSGRDGEIQYSIRDGSGLGRFNIDDESGVITAADSLDRETTASYWLTVYATDRGVVPLYSTIEVYIEVEDVNDNAPLTSEPIYYPVVMENSPKDVSVIQIQAEDPDSGSNEKLTYRITSGNPQNFFAINIKTGLITTTSRKLDREQQAEHFLEVTVTDGGSSPKQSTIWVVVQVLDENDNRPQFPEKVYQIKLPERDRKKRGEPIYRAFAFDKDEGPNAEISYSIVDGNDDGKFFIDPKTGMVSSRKQFTAGSYDILTIKAVDNGRPQKSSTARLHIEWIKKPPPSPIPLTFDEPFYNFTVMESDKVTEIVGVVSVQPANTPLWFDIVGGNFDSSFDAEKGVGTIVIAKPLDAEQRSVYNMSVEVTDGTNIAVTQVFIKVLDNNDNGPEFSQPHYDVTISEDVLPDTEILQIEATDRDEKHKLSYTIHSSIDAVSMRKFRMDPSTGVLYTAERLDHEAQDKHILNIMVRDQEFPYRRNLARVIVNVEDANDHSPYFTNPLYEASVFESAALGSVVLQVTALDKDKGENAELIYSIEAGNTGNTFKIEPVLGIITISKEPDMAAMGQFVLSVKVTDQGSPPMSATAIVRISISMSDNSHPKFTHKDYQAEVNENVDIGTSVILISAISQSTLIYEVKDGNINGVFTINPYSGVITTRRALDYEHTSSYQLIIQATNMAGMASNATISVQIVDENDNPPVFLFSQYSGSLSEAAPINSIVRSLDNSPLVIRATDADSNQNALLVYQIVESTAKKFFTVDSSTGAIRTIANLDHEAIAHFHFHVHVRDSGNPQLTAESPVEVNIEVTDVNDNPPVFTQAVFETVLLLPTYIGVEVLKVSATDPDSEVPPELTYSLMEGSVDNFLMDPNTGVLTIKNNNLSKDHYMLIVRVSDGKFYSTAMVTVMVKEAMDSGLHFTQSFYSTSISENSTNITKVAIVNAVGNRLNEPLKYSILNPGNKFKIKSTSGVIQTTGVPFDREEQELYELVVEASRELDHLRVARVVVRVNIEDVNDNSPVFVGLPYYAAVQVDAEPGTLIYRVTAIDKDKGANGEVTYVLQDDYGHFEINPNSGNVILREAFNSDLSNIDYGVTILAKDGGNPSLSTFVELPITIVNKAMPVFDKPFYTASINEDITMNTPILSINATSPEGQGIIYLIIDGDPFQQFNIDFDTGVLKVISPLDYEVTSVYKLTVRASDALTGARAEVTVDLLVDDINDNPPVFDQPTYNTTLSESSLIGTPVLQLVSTDADSGNNKLVRYQIVQDTYNSTDYFHIDSSSGLILTARMLDHELVQHCTLKVTATDNGFPSLSSEVLVQIYISDVNDNPPVFNQLIYESYVSELAPRGHFVTCVQASDADSSDLDRLEYSILSGNDRASFLMDSKSGVLTLSSHRKQRMEPLYSLNVSVSDGLFTSTAQVHIRVLGANLYSPAFSQSTYVAEVRENAASGTKVIHVRATDGDPGTYGQVSYSIINDFAKDRFLIDSNGQIITTERLDRENPLEGDISIYLRALDGGGRTTFCTVRVIVVDENDNAPQFMTVEYRASVRADVGRGHLVTQVQALDPDDGANSRITYSLYSEASVSVADLLEIDPDNGWMVTKGNFNQLRNTVLSFFVKAVDGGIPVRHSLIPVYIHVLPPETFLPSFTQSQYSFTITEDTSIGSTVDTLRILPNQSVRFSMVNGERPENNKEGVFIIEQETGAIKLDKRLDHEVSPAFHFKVAATIPLDKVDIVFTVDVDVKVLDLNDNKPVFETSTYETIIMEGMPVGTKLAQVRAIDMDWGANGQVTYSLHSDSHLEKVIEAFNIDSNTGWISTLKDLDHETDPAFSFFVVASDLGEAFSLSSMALVSVKVTDINDNAPVFAHEVYRGNVKESDPPGEVVAVLSTLDKDTSNINRQVSYHITGGNPRGQFALGMVQSEWKVYVKRPLDREEQDIYFLNITASDGLFVTQAMVEVTVSDVNDNSPVCDQVAYSASLPEDIPSNKIILKVSAKDADIGSNGDIRYSLYGSGNNEFFLDPESGELKTLAVLDRERVPVYNLIARATDGGGRFCSSSVLLLLEDVNDNPPVFSSNHYTACVYENTATKALLTRVQAMDPDVGINRKVVYSLEDSASGVFSIDSSSGVIVLEQPLDREQQSSYNISVRATDQSPGQSLSSLASVTITVLDINDNPPVFERRDYLVTVPEDTSLGTQVLSVFATSKDIGTNAEITYLIRSGNEQGKFSINPKTGGISVLEALDYETCRRFYLVVEAKDGGTPALSTAATVSIDLTDVNDNPPRFSQDVYSAVISEDALEGDSVILLIAEDVDSKPNGQIRFSIVGGDRDNEFAVDPILGLVKVKKKLDRERVSGYSLLIQAVDSGIPAMSSTTTVNIDISDVNDNSPVFTPANYTAVIQENKPVGTSILQLVVTDRDSFHNGPPFSFSILSGNEDEEFMLDSHGILRSAVVFRHMESPEYLLCIQAKDSGKPQQVSHTYIRVRVIEESTHKPTAIPLEIFIVTMEDDFPGGVIGKIHATDQDMYDVLTFALKSEQKSLFKVNSHDGKIIALGGLDSGKYVLNVSVSDGRFQVPIDVVVHVEQLVHEMLQNTVTIRFEDVSPEDFVGLHMHGFRRILRNAVLTQKQDSLRIISIQPVVGTNQLDMLFAVEMHSSEFYKPAYLIQKLSNARRHLENVMHIAAILEKNCSGLDCQEQHCEQGLSLDSHALMTYSTARISFVCPRFYRNVRCTCNGGVCPGSNDPCVEKPCPEDMQCVGYEASRRPFLCQCPPGKLGECSGHTSLSFAGNSYIKYRLSENSKEEDFKLALRLRTLQSNGIIMYTRANPCMILKIVEGKLWFQLDCGSGPGILGISSRAVNDGSWHSVFLELNRNFTSLALDDSYVERRRAPLYFQTLSTDSAIFFGALVQADNVRSLTDTRVTQVLGGFQGCLDSVVLNHYELPLQNKRSSFAEVVGLTELKLGCVLYPDACQRSPCLHGGSCSSLPSGGYQCSCLSQFTGTNCESEITACFPNPCRNGGSCDPIGNTFVCSCKAGLTGVTCEDDVDECEREECENGGSCVNLFGSFFCNCTPGYVGQYCGLRPVVVPNIQAGHSYVGKEELIGIAVVLFVIFTLIVLFIVFRKKVFRKNYSRNNITLVQDPATAALLHKSNGIPFRSLRAGDGRNVYQEVGPPQVPVRPMAYTPCFQSDSRSNLDKGLDVLGGEPQEMSTFHPESPRILTARRGVVVCSVAPNLPAVSPCRSDCDSIRKNGWDTGSENKGTEDTGEVTCFTNSNKGSNSEVQSLSSFQSDSGDDNAYHWDTSDWMPGARLSDIEEMPNYESQDGGAAHQGSTRELESDYYLGGYDIDSEYPPPHEEEFLSRDQLPPPLPEDFPDQYEALPPSQPTSLTSTMSPDCRRRPRFHPSQYLPPHPLPGETDLGGPSSSCDFSTFAVNMNQGTEVMAPTDSVSLSLHNSRGTSSSEMSARCGFDDSEVAMSDYESAGELSLTNLHIPFVETQQQTQV", "length": 4555 }, "evidence": [ { "id": "HGNC:23112", "url": "https://alliancegenome.org/gene/HGNC:23112#orthology", "database": "AGR" }, { "id": "MGI:2444314", "url": "https://alliancegenome.org/gene/MGI:2444314#orthology", "database": "AGR" }, { "id": "RGD:620657", "url": "https://alliancegenome.org/gene/RGD:620657#orthology", "database": "AGR" }, { "id": "FB:FBgn0261574", "url": "https://alliancegenome.org/gene/FB:FBgn0261574#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-1254", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-1254#orthology", "database": "AGR" }, { "id": "Q8TDW7", "url": "https://omabrowser.org/oma/group/Q8TDW7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R508-1", "protein_name": "Protocadherin Fat 3", "gene_name": "Fat3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGVTMRHCIDTRPPSCLIFLLLKLCATVSQGLPGTGPLGFHFTHALYNATVYENSAARTYVNSQSRMGITLIDLSWDIKYRIVSGDEEGFFKAEEVIIADFCFLRIRTKGGNSAILNREIQDNYLLIIKGSVRGEDLEAWTKVNIQVLDMNDLRPLFSPTTYSVTIAESTPLRTSVAQVTATDADIGSNGEFYYYFKNKVDLFSVHPTSGVISLSGRLNYDEKNRYDLEILAVDRGMKLYGNNGVSSTAKLYVHIERINEHAPIIHVVTHTPFSLDKEPTYAVVTVDDLDEGANGEIESVSIVDGDPLEQFFLAKEGKWMNEYKVKERRQVDWESFSYGYNLTIQAKDKGSPQKFSELKTVHIANPRRDSTPIKFEKDVYDISISEFSPPGVMVAIVKVNPEPLDVEYKLLPGKDAEYFKINPRSGLIVTAQPLNTVKKEVYKLEVSDKEGDAKAQVTIGIEDANDHTPEFQETLYETFVNESVPVGTNVLTVSASDKDKGENGYITYSIASLNLLPFAINQFTGVISTTEELDFESSPETYRFIVRASDWGSPYRHESEVNVTIRVGNVNDNSPLFEKVACQGVISYDFPVGGHITAISAIDIDELELVKYKIISGNELGFFYLNPDSGVLQLKKSLMNSGIKNGNFALRITATDGENFADPMAINISVLHGKVSSKSFSCRETRVAQKLAEKLLIKAKANGKLNQEDGFLDFYSINRQGPHFDKSFPSDVAVKENMPVGTNILKIKAYDADSGFNGKVLFTISDGNTDSCFNIDMETGQLKVLMPMDREHTDLYVLNITIYDLGKPQKSSWRLLTVNVEDANDNSPVFLQDSYSVSILESSSIGTEIIQVEARDKDLGSNGEVTYSVLTDTHQFVINSSTGIVYIADQLDRESKANYSLKIEARDKAESGQQLFSVVTLKIFLDDVNDCSPAFIPSSYSVKVLEDLPVGTVIAWLETQDPDLGLGGQVRYSLVNDYNGRFEIDKASGAIRLSKELDYEKQQFYNLTVRAKDKGRPVSLSSISFVEVEVVDVNENLHTPYFPDFAVVGSVKENSRIGTSVLQVTAHDEDSGRDGEIQYSIRDGSGLGRFNIDDESGVITAADILDRETTASYWLTVYATDRGVVPLYSTIEVYIEVEDVNDNAPLTSEPIYYPVVMENSPKDVSVIQIQAEDPDSGSNEKLTYRITSGNPQNFFAINIKTGLITTTSRKLDREQQAEHFLEVTVTDGGSSPKQSTIWVVVQVLDENDNKPQFPEKVYQIKLPERDRKKRGEPIYRAFAFDRDEGPNAEISYSIVDGNDDGKFFIDPKTGMVSSRKQFTAGSYDILTIKAVDNGRPQKSSTARLHIEWIKKPPPSPIPLTFDEPFYNFTIMESDKVTEIVGVVSVQPANTPLWFDIIGGNFDSSFDAEKGVGTIVIAKPLDAEQRSVYNMSVEVTDGTNVAVTQVFITVLDNNDNGPEFSQPHYDVTISEDVPPDTEILQIEATDRDEKHKLSYTIHSSIDAISMRKFRIDPSTGVLYTAERLDHEAQDKHILNIMVRDQEFPYRRNLARVIVNVEDANDHSPYFTNPLYEASVFESAALGSVVLQVTALDKDKGENAELIYSIEAGNTGNTFKIEPVLGIITISKEPDMTAMGQFVLSVKVTDQGSPPMSATAIVRISISMSDNSHPKFTHKDYQAEVNENVDIGTSVILISAISQSTLIYEVKDGNINGVFTINPYSGVITTRRALDYEHTSSYQLIIQATNMAGMASNATVSVQVVDENDNPPVFLFSQYSGSLSEAAPINSLVRSLDNSPLVIRATDADSNQNALLVYQIVESTAKKFFTVDSSTGAIRTIANLDHEVIAHFHFHVHVRDSGNPQLTAESPVEVNIEVTDVNDNPPVFTQAVFETVLLLPTYVGVEVLKVSATDPDSEVPPELTYSLMEGSVDHFLMDPNTGVLTIKNNNLSKDHYMLIVRVSDGKFYSTAMVTIMVKEAMDSGLHFTQSFYSTSISENSTNITKVAIVNAVGNRLNEPLKYSILNPGNKFKIKSTSGVIQTTGVPFDREEQELYELVVEASRELDHLRVARVVVRVNIEDVNDNSPVFVGLPYYAAVQVDAEPGTLIYRVTAIDKDKGANGEVTYVLQDDYGHFEINPNSGNVILKEAFNSDLSNIDYGVTILAKDGGTPSLSTFVELPITIVNKAMPVFDKPFYTASINEDISINTPILSINATSPEGQGIIYLIIDGDPFQQFNIDFDTGVLKVISPLDYEVMSVYKLTVRASDALTGARAEVTVDLLVDDVNDNPPVFDQPTYNTTLSESSLIGTPVLQLVSTDADSGNNNLVHYQIVQDTYNSTDYFHIDSSSGLILTARMLDHELVQHCTLKVTATDNGFPSLSSEVLVQIYISDVNDNPPVFNQLIYESYVSELAPRGHFVTCVQASDADSSDFDRLEYSILSGNDRTSFLMDSKSGVLTLSSHRKQRMEPLYSLNVSVSDGLFTSTAQVHIRVLGANLYSPAFSQSTYVAEVRENAASGTKVIHVRATDGDPGTYGQVSYSIINDFAKDRFLIDSNGQIITTERLDRENPLEGDISIYLRALDGGGRTTFCTVRVIVVDENDNAPQFMTLEYRASVRADVGRGHLVTQVQALDPDDGANSRITYSLYSEASVSVADLLEIDPDNGWMVTKGNFNQLRNTVLSFFVKAVDGGIPVRHSLIPVYIHVLPPETFLPSFTQSQYSFTIAEDTSIGSTIDTLRILPNQSVRFSTVNGERPENNKENVFIIEQETGAIKLDKRLDHEVSPAFHFKVAATIPLDKVDIVFTVDVDVKVLDLNDNKPVFETSSYETIIMEGMPVGTKLAQVRAIDTDWGANGQVTYSLHSDSHLEKVMEAFNIDSNTGWISTLKDLDHETDPTFSFFVVASDLGEAFSLSSMALVSVKVTDINDNAPVFAHEVYRGNVKESDPPGEVVAVLSTLDKDTSNINRQVSYHITGGNPRGRFALGMVQSEWKVYVKRPLDREEQDIYFLNITASDGLFVTQAMVEVTVSDVNDNSPVCDQVAYSASLPEDIPSNKIILKVSAKDADIGSNGDIRYSLYGSGNSDFFLDPESGELKTLALLDRERVPVYNLIARATDGGGRFCSSTVLLLLEDVNDNPPVFSSNHYTACVYENTATKALLTRVQAVDPDVGINRKVVYSLEDSASGVFSIDSSSGVIVLEQPLDREQQSSYNISVRATDQSPGQSLSSLTSVTITVLDINDNPPVFERRDYLVTVPEDTSLGTQVLSVFATSKDIGTNAEITYLIRSGNEQGKFRINPKTGGISVLEALDYEMCKRFYLVVEAKDGGTPALSTAATVSIDLTDVNDNPPRFSQDVYSAVISEDALEGDSVILLIAEDVDSKPNGQIRFSIVGGDRDNEFAVDPILGLVKVKKKLDRERVSGYSLLIQAVDSGIPAMSSTTTVNIDISDVNDNSPVFTPANYTAVIQENKPVGTSILQLVVTDRDSFHNGPPFSFSILSGNEDEEFMLDSHGILRSAVVFRHMESPEYLLCIQAKDSGKPQQVSHTYIRVRVIEESTHKPTAIPLEIFIVTMEDDFPGGVIGKIHATDQDMYDVLTFALKSEQKSLFKVNSHDGKIIALGGLDSGKYVLNVSVSDGRFQVPIDVVVHVEQLVHEMLQNTVTIRFENVSPEDFVGLHMHGFRRILRNAVLTQKQDSLRIISIQPVVGTNQLDMLFAVEMHSSEFYKPAYLIQKLSNARRHLENVMHIAAILEKNCSGLDCQEQHCEQGLSLDSHALMTYSTARISFVCPRFYRNVRCTCNGGVCPGSNDPCVEKPCPEDMQCVGYEASRRPFLCQCPPGKLGECSGHTSLSFAGNSYIKYRLSENSREEDFKLALRLRTLQSNGIIMYTRANPCMILKIVEGKLWFQLDCGSGPGILGISSRAVNDGSWHSVFLELNRNFTSLSLDDSYVERRRAPLYFQTLSTDSAIFFGALVQADNIRSLTDTRVTQVLGGFQGCLDSVVLNHNELPLQNKRSSFAEVVGLTELKLGCVLYPDACQRSPCLHGGSCSGLPSGGYQCSCLSQFTGTNCESEITACFPNPCRNGGSCDPIGNTFICSCKAGLTGVTCEDDVDECEREECENGGSCVNLFGSFFCNCTPGYVGQYCGLRPVVVPNIQAGHSYVGKEELIGIAVVLFVIFTLIVLFIVFRKKVFRKNYSRNNITLVQDPATAALLHKSNGIPFRSLRAGDGRNVYQEVGPPQVPVRPMAYTPCFQSDSRSNLDKGLDALGGEPQELSTFHPESPRILTARRGVVVCSVAPNLPAVSPCRSDCDSIRKNGWDTGSENKGAEDTGEVTCFANSNKGSNSEVQSLNSFQSDSGDDNAYHWDTSDWMPGARLSDIEEMPNYESQDGGAVHQGSTRELESDYYLGGYDIDSEYPPPHEEEFLSQDQLPPPLPEDFPEQYEALPPSQPTSLTGTMSPDCRRRPRFHPSQYLPPHPLPGETDLGGPPSSCDFSTFAVSMNQGTEVMAPTDSVSLSLHNSRGTSSSDMSARCGFDDSEVAMSDYESAGELSLTNLHIPFVETQHQTQV", "length": 4555 }, "evidence": [ { "id": "HGNC:23112", "url": "https://alliancegenome.org/gene/HGNC:23112#orthology", "database": "AGR" }, { "id": "MGI:2444314", "url": "https://alliancegenome.org/gene/MGI:2444314#orthology", "database": "AGR" }, { "id": "RGD:620657", "url": "https://alliancegenome.org/gene/RGD:620657#orthology", "database": "AGR" }, { "id": "FB:FBgn0261574", "url": "https://alliancegenome.org/gene/FB:FBgn0261574#orthology", "database": "AGR" }, { "id": "Q8TDW7", "url": "https://omabrowser.org/oma/group/Q8TDW7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9NYQ8-1", "protein_name": "Protocadherin Fat 2", "gene_name": "FAT2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTIALLGFAIFLLHCATCEKPLEGILSSSAWHFTHSHYNATIYENSSPKTYVESFEKMGIYLAEPQWAVRYRIISGDVANVFKTEEYVVGNFCFLRIRTKSSNTALLNREVRDSYTLIIQATEKTLELEALTRVVVHILDQNDLKPLFSPPSYRVTISEDMPLKSPICKVTATDADLGQNAEFYYAFNTRSEMFAIHPTSGVVTVAGKLNVTWRGKHELQVLAVDRMRKISEGNGFGSLAALVVHVEPALRKPPAIASVVVTPPDSNDGTTYATVLVDANSSGAEVESVEVVGGDPGKHFKAIKSYARSNEFSLVSVKDINWMEYLHGFNLSLQARSGSGPYFYSQIRGFHLPPSKLSSLKFEKAVYRVQLSEFSPPGSRVVMVRVTPAFPNLQYVLKPSSENVGFKLNARTGLITTTKLMDFHDRAHYQLHIRTSPGQASTVVVIDIVDCNNHAPLFNRSSYDGTLDENIPPGTSVLAVTATDRDHGENGYVTYSIAGPKALPFSIDPYLGIISTSKPMDYELMKRIYTFRVRASDWGSPFRREKEVSIFLQLRNLNDNQPMFEEVNCTGSIRQDWPVGKSIMTMSAIDVDELQNLKYEIVSGNELEYFDLNHFSGVISLKRPFINLTAGQPTSYSLKITASDGKNYASPTTLNITVVKDPHFEVPVTCDKTGVLTQFTKTILHFIGLQNQESSDEEFTSLSTYQINHYTPQFEDHFPQSIDVLESVPINTPLARLAATDPDAGFNGKLVYVIADGNEEGCFDIELETGLLTVAAPLDYEATNFYILNVTVYDLGTPQKSSWKLLTVNVKDWNDNAPRFPPGGYQLTISEDTEVGTTIAELTTKDADSEDNGRVRYTLLSPTEKFSLHPLTGELVVTGHLDRESEPRYILKVEARDQPSKGHQLFSVTDLIITLEDVNDNSPQCITEHNRLKVPEDLPPGTVLTFLDASDPDLGPAGEVRYVLMDGAHGTFRVDLMTGALILERELDFERRAGYNLSLWASDGGRPLARRTLCHVEVIVLDVNENLHPPHFASFVHQGQVQENSPSGTQVIVVAAQDDDSGLDGELQYFLRAGTGLAAFSINQDTGMIQTLAPLDREFASYYWLTVLAVDRGSVPLSSVTEVYIEVTDANDNPPQMSQAVFYPSIQEDAPVGTSVLQLDAWDPDSSSKGKLTFNITSGNYMGFFMIHPVTGLLSTAQQLDRENKDEHILEVTVLDNGEPSLKSTSRVVVGILDVNDNPPIFSHKLFNVRLPERLSPVSPGPVYRLVASDLDEGLNGRVTYSIEDSDEEAFSIDLVTGVVSSSSTFTAGEYNILTIKATDSGQPPLSASVRLHIEWIPWPRPSSIPLAFDETYYSFTVMETDPVNHMVGVISVEGRPGLFWFNISGGDKDMDFDIEKTTGSIVIARPLDTRRRSNYNLTVEVTDGSRTIATQVHIFMIANINHHRPQFLETRYEVRVPQDTVPGVELLRVQAIDQDKGKSLIYTIHGSQDPGSASLFQLDPSSGVLVTVGKLDLGSGPSQHTLTVMVRDQEIPIKRNFVWVTIHVEDGNLHPPRFTQLHYEASVPDTIAPGTELLQVRAMDADRGVNAEVHYSLLKGNSEGFFNINALLGIITLAQKLDQANHAPHTLTVKAEDQGSPQWHDLATVIIHVYPSDRSAPIFSKSEYFVEIPESIPVGSPILLVSAMSPSEVTYELREGNKDGVFSMNSYSGLISTQKKLDHEKISSYQLKIRGSNMAGAFTDVMVVVDIIDENDNAPMFLKSTFVGQISEAAPLYSMIMDKNNNPFVIHASDSDKEANSLLVYKILEPEALKFFKIDPSMGTLTIVSEMDYESMPSFQFCVYVHDQGSPVLFAPRPAQVIIHVRDVNDSPPRFSEQIYEVAIVGPIHPGMELLMVRASDEDSEVNYSIKTGNADEAVTIHPVTGSISVLNPAFLGLSRKLTIRASDGLYQDTALVKISLTQVLDKSLQFDQDVYWAAVKENLQDRKALVILGAQGNHLNDTLSYFLLNGTDMFHMVQSAGVLQTRGVAFDREQQDTHELAVEVRDNRTPQRVAQGLVRVSIEDVNDNPPKFKHLPYYTIIQDGTEPGDVLFQVSATDEDLGTNGAVTYEFAEDYTYFRIDPYLGDISLKKPFDYQALNKYHLKVIARDGGTPSLQSEEEVLVTVRNKSNPLFQSPYYKVRVPENITLYTPILHTQARSPEGLRLIYNIVEEEPLMLFTTDFKTGVLTVTGPLDYESKTKHVFTVRATDTALGSFSEATVEVLVEDVNDNPPTFSQLVYTTSISEGLPAQTPVIQLLASDQDSGRNRDVSYQIVEDGSDVSKFFQINGSTGEMSTVQELDYEAQQHFHVKVRAMDKGDPPLTGETLVVVNVSDINDNPPEFRQPQYEANVSELATCGHLVLKVQAIDPDSRDTSRLEYLILSGNQDRHFFINSSSGIISMFNLCKKHLDSSYNLRVGASDGVFRATVPVYINTTNANKYSPEFQQHLYEAELAENAMVGTKVIDLLAIDKDSGPYGTIDYTIINKLASEKFSINPNGQIATLQKLDRENSTERVIAIKVMARDGGGRVAFCTVKIILTDENDNPPQFKASEYTVSIQSNVSKDSPVIQVLAYDADEGQNADVTYSVNPEDLVKDVIEINPVTGVVKVKDSLVGLENQTLDFFIKAQDGGPPHWNSLVPVRLQVVPKKVSLPKFSEPLYTFSAPEDLPEGSEIGIVKAVAAQDPVIYSLVRGTTPESNKDGVFSLDPDTGVIKVRKPMDHESTKLYQIDVMAHCLQNTDVVSLVSVNIQVGDVNDNRPVFEADPYKAVLTENMPVGTSVIQVTAIDKDTGRDGQVSYRLSADPGSNVHELFAIDSESGWITTLQELDCETCQTYHFHVVAYDHGQTIQLSSQALVQVSITDENDNAPRFASEEYRGSVVENSEPGELVATLKTLDADISEQNRQVTCYITEGDPLGQFGISQVGDEWRISSRKTLDREHTAKYLLRVTASDGKFQASVTVEIFVLDVNDNSPQCSQLLYTGKVHEDVFPGHFILKVSATDLDTDTNAQITYSLHGPGAHEFKLDPHTGELTTLTALDRERKDVFNLVAKATDGGGRSCQADITLHVEDVNDNAPRFFPSHCAVAVFDNTTVKTPVAVVFARDPDQGANAQVVYSLPDSAEGHFSIDATTGVIRLEKPLQVRPQAPLELTVRASDLGTPIPLSTLGTVTVSVVGLEDYLPVFLNTEHSVQVPEDAPPGTEVLQLATLTRPGAEKTGYRVVSGNEQGRFRLDARTGILYVNASLDFETSPKYFLSIECSRKSSSSLSDVTTVMVNITDVNEHRPQFPQDPYSTRVLENALVGDVILTVSATDEDGPLNSDITYSLIGGNQLGHFTIHPKKGELQVAKALDREQASSYSLKLRATDSGQPPLHEDTDIAIQVADVNDNPPRFFQLNYSTTVQENSPIGSKVLQLILSDPDSPENGPPYSFRITKGNNGSAFRVTPDGWLVTAEGLSRRAQEWYQLQIQASDSGIPPLSSLTSVRVHVTEQSHYAPSALPLEIFITVGEDEFQGGMVGKIHATDRDPQDTLTYSLAEEETLGRHFSVGAPDGKIIAAQGLPRGHYSFNVTVSDGTFTTTAGVHVYVWHVGQEALQQAMWMGFYQLTPEELVSDHWRNLQRFLSHKLDIKRANIHLASLQPAEAVAGVDVLLVFEGHSGTFYEFQELASIITHSAKEMEHSVGVQMRSAMPMVPCQGPTCQGQICHNTVHLDPKVGPTYSTARLSILTPRHHLQRSCSCNGTATRFSGQSYVRYRAPAARNWHIHFYLKTLQPQAILLFTNETASVSLKLASGVPQLEYHCLGGFYGNLSSQRHVNDHEWHSILVEEMDASIRLMVDSMGNTSLVVPENCRGLRPERHLLLGGLILLHSSSNVSQGFEGCLDAVVVNEEALDLLAPGKTVAGLLETQALTQCCLHSDYCSQNTCLNGGKCSWTHGAGYVCKCPPQFSGKHCEQGRENCTFAPCLEGGTCILSPKGASCNCPHPYTGDRCEMEARGCSEGHCLVTPEIQRGDWGQQELLIITVAVAFIIISTVGLLFYCRRCKSHKPVAMEDPDLLARSVGVDTQAMPAIELNPLSASSCNNLNQPEPSKASVPNELVTFGPNSKQRPVVCSVPPRLPPAAVPSHSDNEPVIKRTWSSEEMVYPGGAMVWPPTYSRNERWEYPHSEVTQGPLPPSAHRHSTPVVMPEPNGLYGGFPFPLEMENKRAPLPPRYSNQNLEDLMPSRPPSPRERLVAPCLNEYTAISYYHSQFRQGGGGPCLADGGYKGVGMRLSRAGPSYAVCEVEGAPLAGQGQPRVPPNYEGSDMVESDYGSCEEVMF", "length": 4349 }, "evidence": [ { "id": "FB:FBgn0261574", "url": "https://alliancegenome.org/gene/FB:FBgn0261574#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VW71-1", "protein_name": "Fat-like cadherin-related tumor suppressor homolog", "gene_name": "kug", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFTMKIKKYVTPVKRKAFTILQWISLLCSLWLIPTVQSKADEKHTATLEYRLENQLQDLYRFSHSVYNVTIPENSLGKTYAKGVLHERLAGLRVGLNAEVKYRIISGDKEKLFKAEEKLVGDFAFLAIRTRTNNVVLNREKTEEYVIRVKAHVHLHDRNVSSYETEANIHIKVLDRNDLSPLFYPTQYTVVIPEDTPKYQSILKVTADDADLGINGEIYYSLLMDSEYFAIHPTTGEITLLQQLQYAENSHFELTVVAYDRGSWVNHQNHQASKTKVSISVKQVNFYAPEIFTKTFSSVTPTSNPLIYGIVRVNDKDTGINGNIGRLEIVDGNPDGTFLLKAAETKDEYYIELNQFAHLNQQHFIYNLTLLAEDLGTPRRFAYKSVPIQIKPESKNIPIFTQEIYEVSIPETAPINMPVIRLKVSDPDLGKNALVYLEIVGGNEGDEFRINPDSGMLYTAKQLDAEKKSSYTLTVSAIDQANVGSRKQSSAKVKISVQDMNDNDPIFENVNKVISINENNLAGSFVVKLTAKDRDSGENSYISYSIANLNAVPFEIDHFSGIVKTTSLLDFETMKRNYELIIRASDWGLPYRRQTEIKLSIVVKDINDNRPQFERVNCYGKVTKSAPMGTEVFVTSAIDFDAGDIISYRLSDGNEDGCFNLDPTSGSLSISCDLKKTTLTNRILKVSATDGTHFSDDLIINVHLMPEDLGGDSSILHGFGSFECRETGVARRLAETLSLAEKNNVKSASPSVFSDLSLTPSRYGQNVHRPEFVNFPQELSINESVQLGETVAWIEAKDRDLGYNGKLVFAISDGDYDSVFRIDPDRGELQIIGYLDRERQNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVIQKTLATFRLTESARIGTVVHCLHATDADSGINAQVTYALSVECSDFTVNATTGCLRLNKPLDREKQDNYALHITAKDGGSPVLSSEALVYVLVDDVNDNAPVFGVQEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEIQFSLKEETQDEELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDPSLTSDMSIVIMIIDVNENRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLGIFAVNDQGSITSLSQLDAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPLTDKPVYYVNVTEASVENVEIITLKAFDPDIDPTQTITYNIVSGNLVGYFEIDSKTGVIKTTERKLDRENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEFDQRVYKVQVPSSATVNQSIFQVHAIDSDSGENGRITYSIKSGKGKNKFRIDSQRGHIHIAKPLDSDNEFEIHIKAEDNGIPKKSQTARVNIVVVPVNPNSQNAPLIVRKTSENVVDLTENDKPGFLVTQILAVDDDNDQLWYNISNGNDDNTFYIGQDNGNILLSKYLDYETQQSYNLTISVTDGTFTAFTNLLVQVIDINDNPPQFAKDVYHVNISENIEEESVIMQLHATDRDEDKKLFYHLHATQDPSSLALFRIDSISGNVIVTQRLDFEKTAQHILIVFVKDQGAPGKRNYAKIIVNVHDHNDHHPEFTAKIIQSKVPESAAIGSKLAEVRAIDRDSGHNAEIQYSIITGNVGSVFEIDPTFGIITLAGNLNINKIQEYMLQVKAVDLGNPPLSSQIPVHIIVTMSENDPPKFPTNNIAIEIFENLPIGTFVTQVTARSSSSIFFNIISGNINESFRINPSTGVIVINGNIDYESIKVFNLTVKGTNMAAESSCQNIIIHILDANDNIPYFVQNEYVGALPESAAIGSYVLKVHDSSKDHLTLQVKDADVGVNGMVEYHIVDDLAKNFFKIDSTTGAIELLRQLDYETNAGYTFDVTVSDMGKPKLHSTTTAHVTIRVINVNDCPPVFNERELNVTLFLPTFENVFVRQVSAKDADNDTLRFDIVDGNTNECFQIEKYTGIITTRNFEILNNENDRDYALHVRASDGIFSAILIVKIKVLSAIDSNFAFQRESYRFSAFENNTKVATIGLVNVIGNTLDENVEYRILNPTQLFDIGISSGALKTTGVIFDREVKDLYRLFVEAKSMLYDGMNSNVRRAVTSIDISVLDVNDNCPLFVNMPYYATVSIDDPKGTIIMQVKAIDLDSAENGEVRYELKKGNGELFKLDRKSGELSIKQHVEGHNRNYELTVAAYDGAITPCSSEAPLQVKVIDRSMPVFEKQFYTVSVKEDVEMYSALSVSIEAESPLGRSLIYTISSESQSFEIDYNTGSIFVVNELDYEKISSHDVSIRATDSLSGVYAEVVLSVSIMDVNDCYPEIESDIYNLTIPENASFGTQILKINATDNDSGANAKLSYYIESINGQNNSELFYIDVTDGNLYLKTPLDYEQIKYHHIVVNVKDHGSPSLSSRSNVFITVKDLNDNAPCFVEPSYFTKVSVAAVRGQFVALPKAYDKDISDTDSLEYKIVYGNELQTYSIDKLTGVISLQNMLNFTDKSSTVLNISVSDGVHTAYARLKISLLPENVYSPLFDQSTYEAQVPENLLHGHNIITVKASDGDFGTYANLYYEIVSEEMKKIFLIDQTTGVITSKVTFDREKKDEYVVLLKVSDGGGKFGFASLKVIVVDVNDNVPYFLLKEYKMVVSTTVEANQTILTVKAKDDDIVDNGSVHFQIVQKSNDKAVKDVIEINEKTGDIVFKSKAESYGVNSYQFFVRASDRGEPQFHSEVPVSIEIIETDANIPTFEKSSVLLKIIESTPPGTVLTKLHMIGNYTFKFSIAADQDHFMISDSGELILQQTLDREQQESHNLIVVAETSTVPVFFAYADVLIDVRDENDNYPKFDNTFYSASVAENSEKVISLVKVSATDADTGPNGDIRYYLESDTENIQNIFDIDIYSGWITLLTSLDREVQSEYNFKVIAADNGHPKHDAKVPVTIKIVDYNDNAPVFKLPIEGLSVFENALPGTVLINLLLIDPDIEKQEMDFFIVSGDKQAQFQIGKSGELFIAKPLDREQLMFYNLSIIATDGKFTAKANVEIDVKDINDNTPYCLKPRYHISTNESISIGTTLVEVKAIDFDFQSKLRFYLSGKGADDFSIGKESGILKVASALDRETTPKYKLVAHVQDGKDFTQECFSEIIITVNDINDNMPIFSMAQYRVSVPEDAQLNTLITKVHAMDKDFGVNRQIKYSLMGENHDYFKISKSTGIIRLHKSLDRETISLFNLTVKAEDCGVPKLHSIATVAVNILDINDNPPEFSMRQYSCKILENATHGTEVCKVYATSIDIGVNADIHYFIMSGNEQGKFKMDSTTGDLVLNATLDYEMSKFYFLTIQAIDGGTPPLSNNAYVNISILDINDNSPTFLQNLYRINVNEDIFVGSKILDVKATDEDSDVNGLVTYNIERGDNIGQFSIDPKNGTISVSRPLDRETISHYTLEIQACDQGDPQRCNSVPININILDTNDNAPIFSSSNYSVVLQENRLLGYVFLTFKISDADETPNTTPYTFDIRSGNEGGLFRLEQDGSLRTASRFNHNLQDEFVIQVRVFDNGTPPLYSDAWVVVKIIEESQYPPIVTPLEVTINSFEDDFSGAFIGKVHASDQDKYDELNFSLVSGPDDMYQSSKLFNISNNTGKIYAISNLDIGLYKLNVSVSDGKFHVFSIVKINVELVTNDMLKESVVIRFRRISASEFLLSHRKTFMRSIRNIMRCRQKDVILITLQSDYQKASQHAVGNRRARSIDSDLNVVFAVRKQQIIPDSDEFFTSDEIRQTLIDKKNEIENETNLVVEDVLPSTCQSNKNDCVHGECKQILQILKNNVTTTFTDVISFAAPSYIPVNTCVCRPGFDGKHCKETVNACSTDPCSPQRICMPSGSALGYQCVCPKGFSGTYCERKSSKCSNESCDMGLFTAVSFGGKSYAHYKINKVKAKFTLENGFSYSLQIRTVQQTGTLLYASGKVDYNILEIINGAVQYRFDLGSGEGVISVSSINISDGEWHQISLERSLNSAKVMVDNKHVSHGSAPGVNGILNIQSNDIFVGAEVRPHPSIIGYEDIQRGFIGCMANIKIAKESLPLYISGGSTIAALKRFTNVEFKCDPSNVLVRLGICGSQPCANSGICKELDTDVFECACQPRYSGKHCEIDLDPCSSGPCLFGGRCDYHGPNNYSCTCPIHLSGKRCEYGKFCTPNPCKNGGICEEGDGISHCMCRGYTGPTCEIDVDECENQPCGNGATCINEPGSFRCICPSYLTGASCGDPLYSNSISTKLKNFSIEHISGIISGVAVVLVIISCVLCCVVLKRSSSSKRRNRLEKDKNKSSYKEANLNSLVDKDNYCKPNVKLSNLEVNQRPISYTAVPNDNLVLSNRNFVNNLDILRSYGSAGDELENVPFEYQKVNRNKQHVNINSCHSTDADNAYKQEWCEQMHLRTFSENKLNNELKRDFGPSVSRFSTGKLIQVEMPNVCHSSSANFVDYSALANGQYHWDCSDWVRKSHNPLPDITEVPGAEIADSSSLHSNDSNESKSKKAFFVHREDGDVDPTRDIAALNEDIGSEYLDSEAESCLEPFMLPRSSNQPLSRLSSFNNIENEDYKSNTVPLPSKVSHSCKVYLRHPDSYLPTMHFPSETDGESSMTEGPISRMEIKTRRTISENSEEAYLFPCTVGEIGSNSNISVRLCEIEDSELEEFLPQQQTNN", "length": 4699 }, "evidence": [ { "id": "HGNC:23112", "url": "https://alliancegenome.org/gene/HGNC:23112#orthology", "database": "AGR" }, { "id": "MGI:2444314", "url": "https://alliancegenome.org/gene/MGI:2444314#orthology", "database": "AGR" }, { "id": "RGD:620657", "url": "https://alliancegenome.org/gene/RGD:620657#orthology", "database": "AGR" }, { "id": "FB:FBgn0261574", "url": "https://alliancegenome.org/gene/FB:FBgn0261574#orthology", "database": "AGR" }, { "id": "Q8TDW7", "url": "https://omabrowser.org/oma/group/Q8TDW7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q8TDW7", "url": "https://www.uniprot.org/uniprotkb/Q8TDW7" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "Q8TDW7", "url": "https://www.uniprot.org/uniprotkb/Q8TDW7" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "Q8TDW7", "url": "https://www.uniprot.org/uniprotkb/Q8TDW7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "dendrite development", "id": "GO:0016358", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016358", "evidence": [ { "database": "UniProtKB", "id": "Q8TDW7", "url": "https://www.uniprot.org/uniprotkb/Q8TDW7" } ], "pmid": "" }, { "name": "neuron migration", "id": "GO:0001764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001764", "evidence": [ { "database": "UniProtKB", "id": "Q8TDW7", "url": "https://www.uniprot.org/uniprotkb/Q8TDW7" } ], "pmid": "" }, { "name": "animal organ morphogenesis", "id": "GO:0009887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009887", "evidence": [ { "database": "UniProtKB", "id": "Q8TDW7", "url": "https://www.uniprot.org/uniprotkb/Q8TDW7" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "Q8TDW7", "url": "https://www.uniprot.org/uniprotkb/Q8TDW7" } ], "pmid": "" }, { "name": "anatomical structure formation involved in morphogenesis", "id": "GO:0048646", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048646", "evidence": [ { "database": "UniProtKB", "id": "Q8TDW7", "url": "https://www.uniprot.org/uniprotkb/Q8TDW7" } ], "pmid": "" }, { "name": "cell morphogenesis involved in neuron differentiation", "id": "GO:0048667", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048667", "evidence": [ { "database": "UniProtKB", "id": "Q8TDW7", "url": "https://www.uniprot.org/uniprotkb/Q8TDW7" } ], "pmid": "" }, { "name": "cell-cell adhesion mediated by cadherin", "id": "GO:0044331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044331", "evidence": [ { "database": "UniProtKB", "id": "Q8TDW7", "url": "https://www.uniprot.org/uniprotkb/Q8TDW7" } ], "pmid": "" }, { "name": "regulation of plasma membrane bounded cell projection organization", "id": "GO:0120035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0120035", "evidence": [ { "database": "UniProtKB", "id": "Q8TDW7", "url": "https://www.uniprot.org/uniprotkb/Q8TDW7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "Q8TDW7", "url": "https://www.uniprot.org/uniprotkb/Q8TDW7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1007, "end_pos": 1009, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1368, "end_pos": 1370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1430, "end_pos": 1432, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1752, "end_pos": 1754, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1945, "end_pos": 1947, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1994, "end_pos": 1996, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1997, "end_pos": 1999, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2209, "end_pos": 2211, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2293, "end_pos": 2295, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2332, "end_pos": 2334, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2468, "end_pos": 2470, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3001, "end_pos": 3003, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3202, "end_pos": 3204, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3330, "end_pos": 3332, "annotation": "n_glycosylation_sequon" 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