[ { "uniprot_canonical_ac": "Q8NF91-1", "uniprot_ac": "Q8NF91", "uniprot_id": "SYNE1_HUMAN", "mass": { "chemical_mass": 1011086.0, "monoisotopic_mass": 1011086.0 }, "refseq": { "ac": "NP_892006", "name": "nesprin-1 isoform 1 (nesprin-1 giant or enaptin)", "summary": "This gene encodes a spectrin repeat containing protein expressed in skeletal and smooth muscle, and peripheral blood lymphocytes, that localizes to the nuclear membrane. Mutations in this gene have been associated with autosomal recessive spinocerebellar ataxia 8, also referred to as autosomal recessive cerebellar ataxia type 1 or recessive ataxia of Beauce. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_892006" }, "gene_names": [ { "name": "SYNE1", "type": "recommended", "evidence": [ { "id": "Q8NF91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ] }, { "name": "8B", "type": "synonym", "evidence": [ { "id": "NP_892006", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_892006" } ] }, { "name": "AMC3", "type": "synonym", "evidence": [ { "id": "NP_892006", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_892006" } ] }, { "name": "AMCM", "type": "synonym", "evidence": [ { "id": "NP_892006", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_892006" } ] }, { "name": "ARCA1", "type": "synonym", "evidence": [ { "id": "NP_892006", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_892006" } ] }, { "name": "C6orf98", "type": "synonym", "evidence": [ { "id": "NP_892006", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_892006" }, { "id": "Q8NF91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ] }, { "name": "CPG2", "type": "synonym", "evidence": [ { "id": "NP_892006", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_892006" } ] }, { "name": "EDMD4", "type": "synonym", "evidence": [ { "id": "NP_892006", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_892006" } ] }, { "name": "KASH1", "type": "synonym", "evidence": [ { "id": "NP_892006", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_892006" } ] }, { "name": "KIAA0796", "type": "synonym", "evidence": [ { "id": "Q8NF91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ] }, { "name": "KIAA1262", "type": "synonym", "evidence": [ { "id": "Q8NF91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ] }, { "name": "KIAA1756", "type": "synonym", "evidence": [ { "id": "Q8NF91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ] }, { "name": "MYNE1", "type": "synonym", "evidence": [ { "id": "NP_892006", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_892006" }, { "id": "Q8NF91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ] }, { "name": "Nesp1", "type": "synonym", "evidence": [ { "id": "NP_892006", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_892006" } ] }, { "name": "SCAR8", "type": "synonym", "evidence": [ { "id": "NP_892006", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_892006" } ] }, { "name": "SYNE1", "type": "synonym", "evidence": [ { "id": "NP_892006", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_892006" } ] }, { "name": "dJ45H2.2", "type": "synonym", "evidence": [ { "id": "NP_892006", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_892006" } ] } ], "protein_names": [ { "name": "Nesprin-1", "type": "recommended", "evidence": [ { "id": "Q8NF91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#names_and_taxonomy" } ] }, { "name": "CPG2 full length", "type": "synonym", "evidence": [ { "id": "NP_892006", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_892006" } ] }, { "name": "Enaptin", "type": "synonym", "evidence": [ { "id": "Q8NF91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#names_and_taxonomy" } ] }, { "name": "KASH domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_892006", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_892006" }, { "id": "Q8NF91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#names_and_taxonomy" } ] }, { "name": "KASH1", "type": "synonym", "evidence": [ { "id": "Q8NF91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#names_and_taxonomy" } ] }, { "name": "Myne-1", "type": "synonym", "evidence": [ { "id": "Q8NF91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#names_and_taxonomy" } ] }, { "name": "Myocyte nuclear envelope protein 1", "type": "synonym", "evidence": [ { "id": "Q8NF91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#names_and_taxonomy" } ] }, { "name": "Nuclear envelope spectrin repeat protein 1", "type": "synonym", "evidence": [ { "id": "Q8NF91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#names_and_taxonomy" } ] }, { "name": "Synaptic nuclear envelope protein 1", "type": "synonym", "evidence": [ { "id": "Q8NF91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#names_and_taxonomy" } ] }, { "name": "Syne-1", "type": "synonym", "evidence": [ { "id": "Q8NF91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#names_and_taxonomy" } ] }, { "name": "enaptin", "type": "synonym", "evidence": [ { "id": "NP_892006", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_892006" } ] }, { "name": "myocyte nuclear envelope protein 1", "type": "synonym", "evidence": [ { "id": "NP_892006", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_892006" } ] }, { "name": "nesprin 1", "type": "synonym", "evidence": [ { "id": "NP_892006", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_892006" } ] }, { "name": "nesprin-1 isoform 1 (nesprin-1 giant or enaptin)", "type": "synonym", "evidence": [ { "id": "NP_892006", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_892006" } ] }, { "name": "spectrin repeat containing, nuclear envelope 1", "type": "synonym", "evidence": [ { "id": "NP_892006", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_892006" } ] }, { "name": "synaptic nuclear envelope protein 1", "type": "synonym", "evidence": [ { "id": "NP_892006", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_892006" } ] }, { "name": "synaptic nuclei expressed gene 1", "type": "synonym", "evidence": [ { "id": "NP_892006", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_892006" } ] } ], "function": [ { "annotation": "Exome sequencing implicates ancestry-related Mendelian variation at SYNE1 in childhood-onset essential hypertension. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_892006", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_892006" }, { "database": "PubMed", "id": "38716726", "url": "https://glygen.org/publication/PubMed/38716726" } ] }, { "annotation": "Multi-isomeric modular protein which forms a linking network between organelles and the actin cytoskeleton to maintain the subcellular spatial organization. As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. May be involved in nucleus-centrosome attachment and nuclear migration in neural progenitors implicating LINC complex association with SUN1/2 and probably association with cytoplasmic dynein-dynactin motor complexes; SYNE1 and SYNE2 may act redundantly. Required for centrosome migration to the apical cell surface during early ciliogenesis. May be involved in nuclear remodeling during sperm head formation in spermatogenesis; a probable SUN3:SYNE1/KASH1 LINC complex may tether spermatid nuclei to posterior cytoskeletal structures such as the manchette.", "evidence": [ { "database": "UniProtKB", "id": "Q8NF91", "url": "https://www.uniprot.org/uniprotkb/Q8NF91#function" }, { "database": "PubMed", "id": "18396275", "url": "https://glygen.org/publication/PubMed/18396275" }, { "database": "UniProtKB", "id": "Q6ZWR6", "url": "https://www.uniprot.org/uniprotkb/Q6ZWR6#function" }, { "database": "PubMed", "id": "11792814", "url": "https://glygen.org/publication/PubMed/11792814" } ] }, { "annotation": "This gene encodes a spectrin repeat containing protein expressed in skeletal and smooth muscle, and peripheral blood lymphocytes, that localizes to the nuclear membrane. Mutations in this gene have been associated with autosomal recessive spinocerebellar ataxia 8, also referred to as autosomal recessive cerebellar ataxia type 1 or recessive ataxia of Beauce. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].", "evidence": [ { "database": "RefSeq", "id": "NP_892006", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_892006" } ] }, { "annotation": "[Rare forms of autosomal recessive spinocerebellar ataxia associated with mutations in the ANO10 (ATX-ANO10) and SYNE1 (ATX-SYNE1) genes].", "evidence": [ { "database": "RefSeq", "id": "NP_892006", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_892006" }, { "database": "PubMed", "id": "39269294", "url": "https://glygen.org/publication/PubMed/39269294" } ] } ], "disease": [ { "disease_id": "DOID:0050753", "recommended_name": { "id": "DOID:0050753", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050753", "name": "cerebellar ataxia", "description": "A hereditary ataxia that is characterized by ataxia originating in the cerebellum." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "0050753", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050753" } ] }, { "disease_id": "DOID:0070249", "recommended_name": { "id": "DOID:0070249", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070249", "name": "autosomal dominant Emery-Dreifuss muscular dystrophy 4", "description": "An Emery-Dreifuss muscular dystrophy that has_material_basis_in an autosomal dominant mutation of the SYNE1 gene on chromosome 6q25.2." }, "synonyms": [ { "id": "DOID:0070249", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070249", "name": "Emery-Dreifuss muscular dystrophy 4, autosomal dominant", "description": "" }, { "id": "DOID:0070249", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070249", "name": "EDMD4", "description": "" }, { "id": "DOID:0070249", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070249", "name": "Emery-Dreifuss muscular dystrophy 4 with variable features", "description": "" }, { "id": "MONDO:0013071", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013071", "name": "Emery-Dreifuss muscular dystrophy 4, autosomal dominant", "description": "Any autosomal dominant Emery-Dreifuss muscular dystrophy in which the cause of the disease is a mutation in the SYNE1 gene." }, { "id": "MONDO:0013071", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013071", "name": "Emery-Dreifuss muscular dystrophy 4, autosomal dominant", "description": "" }, { "id": "MONDO:0013071", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013071", "name": "SYNE1 autosomal dominant Emery-Dreifuss muscular dystrophy", "description": "" }, { "id": "MONDO:0013071", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013071", "name": "autosomal dominant Emery-Dreifuss muscular dystrophy caused by mutation in SYNE1", "description": "" }, { "id": "MONDO:0013071", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013071", "name": "EDMD4", "description": "" }, { "id": "MIM:612998", "resource": "MIM", "url": "https://www.omim.org/entry/612998", "name": "Emery-Dreifuss muscular dystrophy 4, autosomal dominant", "description": "Emery-Dreifuss muscular dystrophy 4, autosomal dominant" } ], "unlinked_id_list": [], "evidence": [ { "id": "612998", "database": "MIM", "url": "https://www.omim.org/entry/612998" }, { "id": "0070249", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070249" } ] }, { "disease_id": "DOID:0080954", "recommended_name": { "id": "DOID:0080954", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080954", "name": "arthrogryposis multiplex congenita", "description": "A nervous system disease that is characterized by development of multiple joint contractures affecting two or more areas of the body prior to birth." }, "synonyms": [ { "id": "MONDO:0060486", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0060486", "name": "arthrogryposis multiplex congenita 1, neurogenic, with myelin defect", "description": "" }, { "id": "MONDO:0060486", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0060486", "name": "arthrogryposis multiplex congenita, neurogenic, with myelin defect", "description": "" }, { "id": "MONDO:0060486", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0060486", "name": "AMCNMY", "description": "" }, { "id": "MIM:617468", "resource": "MIM", "url": "https://www.omim.org/entry/617468", "name": "Arthrogryposis multiplex congenita 1, neurogenic, with myelin defect", "description": "Arthrogryposis multiplex congenita 1, neurogenic, with myelin defect" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080954", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080954" } ] }, { "disease_id": "DOID:0080979", "recommended_name": { "id": "DOID:0080979", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080979", "name": "arthrogryposis multiplex congenita-3", "description": "An arthrogryposis multiplex congenita that is characterized by decreased fetal movements, hypotonia, variable skeletal defects, including clubfoot and scoliosis, and delayed motor milestones with difficulty walking and that has_material_basis_in homozygous or compound heterozygous mutation in the SYNE1 gene on chromosome 6q25." }, "synonyms": [ { "id": "MONDO:0032778", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0032778", "name": "arthrogryposis multiplex congenita 3, myogenic type", "description": "" }, { "id": "MONDO:0032778", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0032778", "name": "AMCM", "description": "" }, { "id": "MONDO:0032778", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0032778", "name": "arthrogryposis multiplex congenita, myogenic type", "description": "" }, { "id": "MIM:618484", "resource": "MIM", "url": "https://www.omim.org/entry/618484", "name": "Arthrogryposis multiplex congenita 3, myogenic type", "description": "Arthrogryposis multiplex congenita 3, myogenic type" } ], "unlinked_id_list": [], "evidence": [ { "id": "618484", "database": "MIM", "url": "https://www.omim.org/entry/618484" }, { "id": "0080979", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080979" } ] }, { "disease_id": "DOID:0111618", "recommended_name": { "id": "DOID:0111618", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111618", "name": "autosomal recessive spinocerebellar ataxia 8", "description": "An autosomal recessive cerebellar ataxia characterized by slowly progressive neurodegeneration resulting in gait ataxia and other cerebellar signs, spasticity, secondary musculoskeletal abnormalities, and ocular movement anomalies that has_material_basis_in homozygous or compound heterozygous mutation in SYNE1 on chromosome 6q25.2." }, "synonyms": [ { "id": "DOID:0111618", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111618", "name": "ARCA1", "description": "" }, { "id": "DOID:0111618", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111618", "name": "Autosomal recessive cerebellar ataxia type 1", "description": "" }, { "id": "DOID:0111618", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111618", "name": "SCAR8", "description": "" }, { "id": "DOID:0111618", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111618", "name": "autosomal recessive ataxia, Beauce type", "description": "" }, { "id": "DOID:0111618", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111618", "name": "SYNE1-related autosomal recessive cerebellar ataxia", "description": "" }, { "id": "DOID:0111618", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111618", "name": "recessive ataxia of Beauce", "description": "" }, { "id": "MONDO:0012549", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012549", "name": "autosomal recessive ataxia, Beauce type", "description": "A rare disorder characterized by a slowly progressive pure cerebellar ataxia associated with dysarthria. It has been described in 53 individuals from 26 families of Canadian origin. The mode of transmission is autosomal recessive. Positional cloning has led to the identification of several gene mutations." }, { "id": "MONDO:0012549", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012549", "name": "ARCA1", "description": "" }, { "id": "MONDO:0012549", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012549", "name": "SCAR8", "description": "" }, { "id": "MONDO:0012549", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012549", "name": "autosomal recessive cerebellar ataxia type 1", "description": "" }, { "id": "MONDO:0012549", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012549", "name": "spinocerebellar ataxia, autosomal recessive type 8", "description": "" }, { "id": "MONDO:0012549", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012549", "name": "SYNE1-related autosomal recessive cerebellar ataxia", "description": "" }, { "id": "MONDO:0012549", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012549", "name": "autosomal recessive ataxia Beauce type", "description": "" }, { "id": "MONDO:0012549", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012549", "name": "autosomal recessive spinocerebellar ataxia 8", "description": "" }, { "id": "MONDO:0012549", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012549", "name": "recessive ataxia of Beauce", "description": "" }, { "id": "MONDO:0012549", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012549", "name": "spinocerebellar ataxia autosomal recessive 8", "description": "" }, { "id": "MONDO:0012549", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012549", "name": "spinocerebellar ataxia, autosomal recessive 8", "description": "" }, { "id": "MIM:610743", "resource": "MIM", "url": "https://www.omim.org/entry/610743", "name": "Spinocerebellar ataxia, autosomal recessive, 8", "description": "Spinocerebellar ataxia, autosomal recessive, 8" } ], "unlinked_id_list": [], "evidence": [ { "id": "610743", "database": "MIM", "url": "https://www.omim.org/entry/610743" }, { "id": "0111618", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111618" } ] }, { "disease_id": "DOID:11726", "recommended_name": { "id": "DOID:11726", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11726", "name": "Emery-Dreifuss muscular dystrophy", "description": "A muscular dystrophy that chiefly affects muscles used for movement (skeletal) and heart (cardiac) muscle." }, "synonyms": [ { "id": "DOID:11726", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11726", "name": "EDMD", "description": "" }, { "id": "MONDO:0100531", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100531", "name": "Emery-Dreifuss muscular dystrophy 1, X-linked", "description": "" }, { "id": "MONDO:0100531", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100531", "name": "EDMD1", "description": "" }, { "id": "MONDO:0100531", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100531", "name": "EMD1", "description": "" }, { "id": "MONDO:0100531", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100531", "name": "Emery-Dreifuss muscular dystrophy 1, X-linked", "description": "" }, { "id": "MONDO:0100531", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100531", "name": "Humeroperoneal neuromuscular disease", "description": "" }, { "id": "MIM:310300", "resource": "MIM", "url": "https://www.omim.org/entry/310300", "name": "Emery-Dreifuss muscular dystrophy 1, X-linked", "description": "Emery-Dreifuss muscular dystrophy 1, X-linked" } ], "unlinked_id_list": [], "evidence": [ { "id": "11726", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11726" } ] }, { "disease_id": "DOID:3312", "recommended_name": { "id": "DOID:3312", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3312", "name": "bipolar disorder", "description": "A mood disorder that involves alternating periods of mania and depression." }, "synonyms": [ { "id": "DOID:3312", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3312", "name": "Manic Bipolar Affective disorder", "description": "" }, { "id": "DOID:3312", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3312", "name": "Manic Depressive disorder", "description": "" }, { "id": "DOID:3312", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3312", "name": "Manic bipolar I disorder", "description": "" }, { "id": "DOID:3312", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3312", "name": "bipolar depression", "description": "" }, { "id": "DOID:3312", "resource": "Disease Ontology", "url": 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"https://monarchinitiative.org/disease/MONDO:0012758", "name": "HPC13", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "HPC11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "HPC14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "HPC15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0700275", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0700275", "name": "prostate cancer, hereditary", "description": "An instance of prostate cancer that is caused by an inherited genomic modification in an individual. Familial prostate cancer (FPC) is a malignant tumor of the prostate with an early onset. FPC is either asymptomatic or causes mictionary symptoms, erectile dysfunction, bone pain, venous compression and infectious or inflammatory syndrome (for the metastatic forms). It is also characterized by familial antecedents." }, { "id": "MIM:601518", "resource": "MIM", "url": "https://www.omim.org/entry/601518", "name": "Prostate cancer, hereditary, 1", "description": "Prostate cancer, hereditary, 1" }, { "id": "MIM:610997", "resource": "MIM", "url": "https://www.omim.org/entry/610997", "name": "Prostate cancer, hereditary, 9", "description": "Prostate cancer, hereditary, 9" }, { "id": "MIM:611868", "resource": "MIM", "url": "https://www.omim.org/entry/611868", "name": "Prostate cancer, hereditary, 12", "description": "Prostate cancer, hereditary, 12" }, { "id": "MIM:611928", "resource": "MIM", "url": "https://www.omim.org/entry/611928", "name": "Prostate cancer, hereditary, 13", "description": "Prostate cancer, hereditary, 13" }, { "id": "MIM:611955", "resource": "MIM", "url": "https://www.omim.org/entry/611955", "name": "Prostate cancer, hereditary, 11", "description": "Prostate cancer, hereditary, 11" }, { "id": "MIM:176807", "resource": "MIM", "url": "https://www.omim.org/entry/176807", "name": "Prostate cancer", "description": "Prostate cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ] } ] }, { "significant": "Yes", "trend": "down", "name": "Stomach cancer [DO disease name]", "url": "https://disease-ontology.org/term/DOID:10534", "evidence": [ { "database": "BioXpress", "id": "Q8NF91", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/Q8NF91" } ], "disease": [ { "disease_id": "DOID:10534", "recommended_name": { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach." }, "synonyms": [ { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "gastric cancer", "description": "" }, { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "A primary or metastatic malignant neoplasm involving the stomach." }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca lesser curvature - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "GC", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "cancer of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer risk after h. pylori infection", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer, somatic", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumor", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumour", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant stomach neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "stomach cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca body - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "ca greater curvature of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of body of stomach", "description": "" }, { "id": "MIM:613659", "resource": "MIM", "url": "https://www.omim.org/entry/613659", "name": "Gastric cancer", "description": "Gastric cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" }, { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ] } ] }, { "significant": "Yes", "trend": "down", "name": "Urinary bladder cancer [DO disease name]", "url": "https://disease-ontology.org/term/DOID:11054", "evidence": [ { "database": "BioXpress", "id": "Q8NF91", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/Q8NF91" } ], "disease": [ { "disease_id": "DOID:11054", "recommended_name": { "id": "DOID:11054", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11054", "name": "urinary bladder cancer", "description": "An urinary system cancer that results_in malignant growth located_in the urinary bladder." }, "synonyms": [ { "id": "DOID:11054", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11054", "name": "bladder cancer", "description": "" }, { "id": "DOID:11054", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11054", "name": "tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder cancer", "description": "A primary or metastatic malignant neoplasm involving the bladder." }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "tumour of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "bladder cancer, somatic", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "cancer of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant bladder tumour", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm, bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant neoplasm, urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumor, urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of the bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of the urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant tumour of urinary bladder", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "malignant urinary bladder tumour", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder cancer", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder malignant neoplasm", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder malignant tumor", "description": "" }, { "id": "MONDO:0001187", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001187", "name": "urinary bladder malignant tumour", "description": "" }, { "id": "MIM:109800", "resource": "MIM", "url": "https://www.omim.org/entry/109800", "name": "Bladder cancer", "description": "Bladder cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "11054", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11054" } ] } ] }, { "significant": "Yes", "trend": "down", "name": "Head and neck cancer [DO disease name]", "url": "https://disease-ontology.org/term/DOID:11934", "evidence": [ { "database": "BioXpress", "id": "Q8NF91", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/Q8NF91" } ], "disease": [ { "disease_id": "DOID:11934", "recommended_name": { "id": "DOID:11934", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11934", "name": "head and neck cancer", "description": "An organ system cancer that arises in the head or neck region. This region includes the nasal cavity, sinuses, lips, mouth, salivary glands, throat, or larynx." }, "synonyms": [ { "id": "DOID:11934", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11934", "name": "head and neck neoplasm", "description": "" }, { "id": "DOID:11934", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11934", "name": "head and neck tumours", "description": "" }, { "id": "DOID:11934", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11934", "name": "head/neck neoplasm", "description": "" }, { "id": "DOID:11934", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11934", "name": "tumor of head and neck", "description": "" } ], "unlinked_id_list": [ "DOID:1542" ], "evidence": [ { "id": "11934", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11934" } ] } ] }, { "significant": "Yes", "trend": "down", "name": "Lung cancer [DO disease name]", "url": "https://disease-ontology.org/term/DOID:1324", "evidence": [ { "database": "BioXpress", "id": "Q8NF91", "url": "https://hive.biochemistry.gwu.edu/bioxpress/transcriptview/Q8NF91" } ], "disease": [ { "disease_id": "DOID:1324", "recommended_name": { "id": "DOID:1324", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung." }, "synonyms": [ { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer", "description": "A malignant neoplasm involving the lung." }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "adenocarcinoma of lung, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "adenocarcinoma of lung, somatic", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "cancer of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, protection against, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, resistance to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, somatic", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung neoplasm", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung tumor", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung tumour", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant neoplasm of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant neoplasm of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumor of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumor of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumour of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumour of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "nonsmall cell lung cancer, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": 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"description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "lung cancer susceptibility 3", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "LNCR3", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "lung cancer susceptibility 3", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "lung cancer susceptibility 4", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "LNCR4", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "lung cancer susceptibility 4", "description": "" }, { "id": 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"Other", "Protein Classification" ] }, { "id": "PF27015", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27015", "database": "Pfam", "categories": [ "Other", "Protein Classification" ] }, { "id": "Q8NF91", "url": "https://pharos.nih.gov/targets/Q8NF91", "database": "PHAROS", "categories": [ "Organism-specific" ] }, { "id": "PR:Q8NF91", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q8NF91", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-HSA-1221632", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1221632", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_892006", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_892006", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A0C4DG40", "url": "https://www.uniprot.org/uniprotkb/A0A0C4DG40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0C4DG40-1", "url": "https://www.uniprot.org/uniprotkb/A0A0C4DG40-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0C4DH48", "url": "https://www.uniprot.org/uniprotkb/A0A0C4DH48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0C4DH48-1", "url": "https://www.uniprot.org/uniprotkb/A0A0C4DH48-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5F9ZH00", "url": "https://www.uniprot.org/uniprotkb/A0A5F9ZH00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5F9ZH00-1", "url": "https://www.uniprot.org/uniprotkb/A0A5F9ZH00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5F9ZH86", "url": "https://www.uniprot.org/uniprotkb/A0A5F9ZH86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5F9ZH86-1", "url": "https://www.uniprot.org/uniprotkb/A0A5F9ZH86-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5F9ZH87", "url": "https://www.uniprot.org/uniprotkb/A0A5F9ZH87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5F9ZH87-1", "url": "https://www.uniprot.org/uniprotkb/A0A5F9ZH87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5F9ZHB2", "url": "https://www.uniprot.org/uniprotkb/A0A5F9ZHB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5F9ZHB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A5F9ZHB2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5F9ZHD7", "url": "https://www.uniprot.org/uniprotkb/A0A5F9ZHD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5F9ZHD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A5F9ZHD7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5F9ZHE1", "url": "https://www.uniprot.org/uniprotkb/A0A5F9ZHE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5F9ZHE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A5F9ZHE1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5F9ZHI3", "url": "https://www.uniprot.org/uniprotkb/A0A5F9ZHI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5F9ZHI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5F9ZHI3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5F9ZHR3", "url": "https://www.uniprot.org/uniprotkb/A0A5F9ZHR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5F9ZHR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A5F9ZHR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5F9ZI52", "url": "https://www.uniprot.org/uniprotkb/A0A5F9ZI52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A5F9ZI52-1", "url": "https://www.uniprot.org/uniprotkb/A0A5F9ZI52-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F5GXQ8", "url": "https://www.uniprot.org/uniprotkb/F5GXQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F5GXQ8-1", "url": "https://www.uniprot.org/uniprotkb/F5GXQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F5GYQ7", "url": "https://www.uniprot.org/uniprotkb/F5GYQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F5GYQ7-1", "url": "https://www.uniprot.org/uniprotkb/F5GYQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F5GZ83", "url": "https://www.uniprot.org/uniprotkb/F5GZ83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F5GZ83-1", "url": "https://www.uniprot.org/uniprotkb/F5GZ83-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F5H422", "url": "https://www.uniprot.org/uniprotkb/F5H422", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F5H422-1", "url": "https://www.uniprot.org/uniprotkb/F5H422-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F5H4Q0", "url": "https://www.uniprot.org/uniprotkb/F5H4Q0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F5H4Q0-1", "url": "https://www.uniprot.org/uniprotkb/F5H4Q0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F5H6R8", "url": "https://www.uniprot.org/uniprotkb/F5H6R8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F5H6R8-1", "url": "https://www.uniprot.org/uniprotkb/F5H6R8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F8WAI0", "url": "https://www.uniprot.org/uniprotkb/F8WAI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F8WAI0-1", "url": "https://www.uniprot.org/uniprotkb/F8WAI0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H0Y325", "url": "https://www.uniprot.org/uniprotkb/H0Y325", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H0Y325-1", "url": "https://www.uniprot.org/uniprotkb/H0Y325-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H0Y326", "url": "https://www.uniprot.org/uniprotkb/H0Y326", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H0Y326-1", "url": "https://www.uniprot.org/uniprotkb/H0Y326-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H0YFT4", "url": "https://www.uniprot.org/uniprotkb/H0YFT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H0YFT4-1", "url": "https://www.uniprot.org/uniprotkb/H0YFT4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H0YGD3", "url": "https://www.uniprot.org/uniprotkb/H0YGD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "H0YGD3-1", "url": "https://www.uniprot.org/uniprotkb/H0YGD3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5JV20", "url": "https://www.uniprot.org/uniprotkb/Q5JV20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5JV20-1", "url": "https://www.uniprot.org/uniprotkb/Q5JV20-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8NF91", "url": "https://www.uniprot.org/uniprotkb/Q8NF91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8NF91-1", "url": "https://www.uniprot.org/uniprotkb/Q8NF91-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8NF91-10", "url": "https://www.uniprot.org/uniprotkb/Q8NF91-10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8NF91-11", "url": "https://www.uniprot.org/uniprotkb/Q8NF91-11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8NF91-12", "url": "https://www.uniprot.org/uniprotkb/Q8NF91-12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8NF91-2", "url": "https://www.uniprot.org/uniprotkb/Q8NF91-2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8NF91-3", "url": "https://www.uniprot.org/uniprotkb/Q8NF91-3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8NF91-4", "url": "https://www.uniprot.org/uniprotkb/Q8NF91-4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8NF91-5", "url": "https://www.uniprot.org/uniprotkb/Q8NF91-5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8NF91-6", "url": "https://www.uniprot.org/uniprotkb/Q8NF91-6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8NF91-7", "url": "https://www.uniprot.org/uniprotkb/Q8NF91-7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8NF91-8", "url": "https://www.uniprot.org/uniprotkb/Q8NF91-8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8NF91-9", "url": "https://www.uniprot.org/uniprotkb/Q8NF91-9", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATSRGASRCPRDIANVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGVKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRKIKLVNINSTDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSIVSSETPSPPSKRKVTTKIQGNAKKALLKWVQYTAGKQTGIEVKDFGKSWRSGVAFHSVIHAIRPELVDLETVKGRSNRENLEDAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDIHNASTDGQEDDEILPGFPSFANSVQNFKREDRVIFKEMKVWIEQFERDLTRAQMVESNLQDKYQSFKHFRVQYEMKRKQIEHLIQPLHRDGKLSLDQALVKQSWDRVTSRLFDWHIQLDKSLPAPLGTIGAWLYRAEVALREEITVQQVHEETANTIQRKLEQHKDLLQNTDAHKRAFHEIYRTRSVNGIPVPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVEQLLQNYVSFIENSKFFEQYEVTYQILKQTAEMYVKADGSVEEAENVMKFMNETTAQWRNLSVEVRSVRSMLEEVISNWDRYGNTVASLQAWLEDAEKMLNQSENAKKDFFRNLPHWIQQHTAMNDAGNFLIETCDEMVSRDLKQQLLLLNGRWRELFMEVKQYAQADEMDRMKKEYTDCVVTLSAFATEAHKKLSEPLEVSFMNVKLLIQDLEDIEQRVPVMDAQYKIITKTAHLITKESPQEEGKEMFATMSKLKEQLTKVKECYSPLLYESQQLLIPLEELEKQMTSFYDSLGKINEIITVLEREAQSSALFKQKHQELLACQENCKKTLTLIEKGSQSVQKFVTLSNVLKHFDQTRLQRQIADIHVAFQSMVKKTGDWKKHVETNSRLMKKFEESRAELEKVLRIAQEGLEEKGDPEELLRRHTEFFSQLDQRVLNAFLKACDELTDILPEQEQQGLQEAVRKLHKQWKDLQGEAPYHLLHLKIDVEKNRFLASVEECRTELDRETKLMPQEGSEKIIKEHRVFFSDKGPHHLCEKRLQLIEELCVKLPVRDPVRDTPGTCHVTLKELRAAIDSTYRKLMEDPDKWKDYTSRFSEFSSWISTNETQLKGIKGEAIDTANHGEVKRAVEEIRNGVTKRGETLSWLKSRLKVLTEVSSENEAQKQGDELAKLSSSFKALVTLLSEVEKMLSNFGDCVQYKEIVKNSLEELISGSKEVQEQAEKILDTENLFEAQQLLLHHQQKTKRISAKKRDVQQQIAQAQQGEGGLPDRGHEELRKLESTLDGLERSRERQERRIQVTLRKWERFETNKETVVRYLFQTGSSHERFLSFSSLESLSSELEQTKEFSKRTESIAVQAENLVKEASEIPLGPQNKQLLQQQAKSIKEQVKKLEDTLEEDIKTMEMVKTKWDHFGSNFETLSVWITEKEKELNALETSSSAMDMQISQIKVTIQEIESKLSSIVGLEEEAQSFAQFVTTGESARIKAKLTQIRRYGEELREHAQCLEGTILGHLSQQQKFEENLRKIQQSVSEFEDKLAVPIKICSSATETYKVLQEHMDLCQALESLSSAITAFSASARKVVNRDSCVQEAAALQQQYEDILRRAKERQTALENLLAHWQRLEKELSSFLTWLERGEAKASSPEMDISADRVKVEGELQLIQALQNEVVSQASFYSKLLQLKESLFSVASKDDVKMMKLHLEQLDERWRDLPQIINKRINFLQSVVAEHQQFDELLLSFSVWIKLFLSELQTTSEISIMDHQVALTRHKDHAAEVESKKGELQSLQGHLAKLGSLGRAEDLHLLQGKAEDCFQLFEEASQVVERRQLALSHLAEFLQSHASLSGILRQLRQTVEATNSMNKNESDLIEKDLNDALQNAKALESAAVSLDGILSKAQYHLKIGSSEQRTSCRATADQLCGEVERIQNLLGTKQSEADALAVLKKAFQDQKEELLKSIEDIEERTDKERLKEPTRQALQQRLRVFNQLEDELNSHEHELCWLKDKAKQIAQKDVAFAPEVDREINRLEVTWDDTKRLIHENQGQCCGLIDLMREYQNLKSAVSKVLENASSVIVTRTTIKDQEDLKWAFSKHETAKNKMNYKQKDLDNFTSKGKHLLSELKKIHSSDFSLVKTDMESTVDKWLDVSEKLEENMDRLRVSLSIWDDVLSTRDEIEGWSNNCVPQMAENISNLDNHLRAEELLKEFESEVKNKALRLEELHSKVNDLKELTKNLETPPDLQFIEADLMQKLEHAKEITEVAKGTLKDFTAQSTQVEKFINDITTWFTKVEESLMNCAQNETCEALKKVKDIQKELQSQQSNISSTQENLNSLCRKYHSAELESLGRAMTGLIKKHEAVSQLCSKTQASLQESLEKHFSESMQEFQEWFLGAKAAAKESSDRTGDSKVLEAKLHDLQNILDSVSDGQSKLDAVTQEGQTLYAHLSKQIVSSIQEQITKANEEFQAFLKQCLKDKQALQDCASELGSFEDQHRKLNLWIHEMEERFNTENLGESKQHIPEKKNEVHKVEMFLGELLAARESLDKLSQRGQLLSEEGHGAGQEGRLCSQLLTSHQNLLRMTKEKLRSCQVALQEHEALEEALQSMWFWVKAIQDRLACAESTLGSKDTLEKRLSQIQDILLMKGEGEVKLNMAIGKGEQALRSSNKEGQRVIQTQLETLKEVWADIMSSSVHAQSTLESVISQWNDYVERKNQLEQWMESVDQKIEHPLQPQPGLKEKFVLLDHLQSILSEAEDHTRALHRLIAKSRELYEKTEDESFKDTAQEELKTQFNDIMTVAKEKMRKVEEIVKDHLMYLDAVHEFTDWLHSAKEELHRWSDMSGDSSATQKKLSKIKELIDSREIGASRLSRVESLAPEVKQNTTASGCELMHTEMQALRADWKQWEDSVFQTQSCLENLVSQMALSEQEFSGQVAQLEQALEQFSALLKTWAQQLTLLEGKNTDEEIVECWHKGQEILDALQKAEPRTEDLKSQLNELCRFSRDLSTYSGKVSGLIKEYNCLCLQASKGCQNKEQILQQRFRKAFRDFQQWLVNAKITTAKCFDIPQNISEVSTSLQKIQEFLSESENGQHKLNMMLSKGELLSTLLTKEKAKGIQAKVTAAKEDWKNFHSNLHQKESALENLKIQMKDFEVSAEPIQDWLSKTEKMVHESSNRLYDLPAKRREQQKLQSVLEEIHCYEPQLNRLKEKAQQLWEGQAASKSFRHRVSQLSSQYLALSNLTKEKVSRLDRIVAEHNQFSLGIKELQDWMTDAIHMLDSYCHPTSDKSVLDSRTLKLEALLSVKQEKEIQMKMIVTRGESVLQNTSPEGIPTIQQQLQSVKDMWASLLSAGIRCKSQLEGALSKWTSYQDGVRQFSGWMDSMEANLNESERQHAELRDKTTMLGKAKLLNEEVLSYSSLLETIEVKGAGMTEHYVTQLELQDLQERYRAIQERAKEAVTKSEKLVRLHQEYQRDLKAFEVWLGQEQEKLDQYSVLEGDAHTHETTLRDLQELQVHCAEGQALLNSVLHTREDVIPSGIPQAEDRALESLRQDWQAYQHRLSETRTQFNNVVNKLRLMEQKFQQVDEWLKTAEEKVSPRTRRQSNRATKEIQLHQMKKWHEEVTAYRDEVEEVGARAQEILDESHVNSRMGCQATQLTSRYQALLLQVLEQIKFLEEEIQSLEESESSLSSYSDWYGSTHKNFKNVATKIDKVDTVMMGKKLKTLEVLLKDMEKGHSLLKSAREKGERAVKYLEEGEAERLRKEIHDHMEQLKELTSTVRKEHMTLEKGLHLAKEFSDKCKALTQWIAEYQEILHVPEEPKMELYEKKAQLSKYKSLQQTVLSHEPSVKSVREKGEALLELVQDVTLKDKIDQLQSDYQDLCSIGKEHVFSLEAKVKDHEDYNSELQEVEKWLLQMSGRLVAPDLLETSSLETITQQLAHHKAMMEEIAGFEDRLNNLQMKGDTLIGQCADHLQAKLKQNVHAHLQGTKDSYSAICSTAQRMYQSLEHELQKHVSRQDTLQQCQAWLSAVQPDLEPSPQPPLSRAEAIKQVKHFRALQEQARTYLDLLCSMCDLSNASVKTTAKDIQQTEQTIEQKLVQAQNLTQGWEEIKHLKSELWIYLQDADQQLQNMKRRHSELELNIAQNMVSQVKDFVKKLQSKQASVNTIIEKVNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNVVEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNLDDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIAEALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALSDAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDDVSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQKCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESSELHTQLAKYQNILEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQEAILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGEAVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQQLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDPLAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELSGPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLAELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQELLQLAGNGLDVESAEENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRDSGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKALVSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILEDAVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSALGMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMVETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGLYTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKLKAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELHQQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYILHQTLLEESKEIDSELEAMTEKLQYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQDAAKDMKKFEAELKKLQAALEQAQATLTSPEVGRLSLKEQLSHRQHLLSEMESLKPKVQAVQLCQSALRIPEDVVASLPLCHAALRLQEEASRLQHTAIQQCNIMQEAVVQYEQYEQEMKHLQQLIEGAHREIEDKPVATSNIQELQAQISRHEELAQKIKGYQEQIASLNSKCKMLTMKAKHATMLLTVTEVEGLAEGTEDLDGELLPTPSAHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEISSPPACRSPSPVANTDASVNQDIAYYQALSAERLQTDAAKIHPSTSASQEFYEPGLEPSATAKLGDLQRSWETLKNVISEKQRTLYEALERQQKYQDSLQSISTKMEAIELKLSESPEPGRSPESQMAEHQALMDEILMLQDEINELQSSLAEELVSESCEADPAEQLALQSTLTVLAERMSTIRMKASGKRQLLEEKLNDQLEEQRQEQALQRYRCEADELDSWLLSTKATLDTALSPPKEPMDMEAQLMDCQNMLVEIEQKVVALSELSVHNENLLLEGKAHTKDEAEQLAGKLRRLKGSLLELQRALHDKQLNMQGTAQEKEESDVDLTATQSPGVQEWLAQARTTWTQQRQSSLQQQKELEQELAEQKSLLRSVASRGEEILIQHSAAETSGDAGEKPDVLSQELGMEGEKSSAEDQMRMKWESLHQEFSTKQKLLQNVLEQEQEQVLYSRPNRLLSGVPLYKGDVPTQDKSAVTSLLDGLNQAFEEVSSQSGGAKRQSIHLEQKLYDGVSATSTWLDDVEERLFVATALLPEETETCLFNQEILAKDIKEMSEEMDKNKNLFSQAFPENGDNRDVIEDTLGCLLGRLSLLDSVVNQRCHQMKERLQQILNFQNDLKVLFTSLADNKYIILQKLANVFEQPVAEQIEAIQQAEDGLKEFDAGIIELKRRGDKLQVEQPSMQELSKLQDMYDELMMIIGSRRSGLNQNLTLKSQYERALQDLADLLETGQEKMAGDQKIIVSSKEEIQQLLDKHKEYFQGLESHMILTETLFRKIISFAVQKETQFHTELMAQASAVLKRAHKRGVELEYILETWSHLDEDQQELSRQLEVVESSIPSVGLVEENEDRLIDRITLYQHLKSSLNEYQPKLYQVLDDGKRLLISISCSDLESQLNQLGECWLSNTNKMSKELHRLETILKHWTRYQSESADLIHWLQSAKDRLEFWTQQSVTVPQELEMVRDHLNAFLEFSKEVDAQSSLKSSVLSTGNQLLRLKKVDTATLRSELSRIDSQWTDLLTNIPAVQEKLHQLQMDKLPSRHAISEVMSWISLMENVIQKDEDNIKNSIGYKAIHEYLQKYKGFKIDINCKQLTVDFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNKSWQILQGLVTEKIQLLEGLLESWSEYENNVQCLKTWFETQEKRLKQQHRIGDQASVQNALKDCQDLEDLIKAKEKEVEKIEQNGLALIQNKKEDVSSIVMSTLRELGQTWANLDHMVGQLKILLKSVLDQWSSHKVAFDKINSYLMEARYSLSRFRLLTGSLEAVQVQVDNLQNLQDDLEKQERSLQKFGSITNQLLKECHPPVTETLTNTLKEVNMRWNNLLEEIAEQLQSSKALLQLWQRYKDYSKQCASTVQQQEDRTNELLKAATNKDIADDEVATWIQDCNDLLKGLGTVKDSLFFLHELGEQLKQQVDASAASAIQSDQLSLSQHLCALEQALCKQQTSLQAGVLDYETFAKSLEALEAWIVEAEEILQGQDPSHSSDLSTIQERMEELKGQMLKFSSMAPDLDRLNELGYRLPLNDKEIKRMQNLNRHWSLISSQTTERFSKLQSFLLQHQTFLEKCETWMEFLVQTEQKLAVEISGNYQHLLEQQRAHELFQAEMFSRQQILHSIIIDGQRLLEQGQVDDRDEFNLKLTLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYREMAEKLRKWLVEVSYLPMSGLGSVPIPLQQARTLFDEVQFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELAEIQEKWKSASMRLEEQKKKLAFLLKDWEKCEKGIADSLEKLRTFKKKLSQSLPDHHEELHAEQMRCKELENAVGSWTDDLTQLSLLKDTLSAYISADDISILNERVELLQRQWEELCHQLSLRRQQIGERLNEWAVFSEKNKELCEWLTQMESKVSQNGDILIEEMIEKLKKDYQEEIAIAQENKIQLQQMGERLAKASHESKASEIEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVYDSCNSEEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTVAKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELRRYCQEVFGRVERYHKKLIRLPLPDDEHDLSDRELELEDSAALSDLHWHDRSADSLLSPQPSSNLSLSLAQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESAMSRALPSEDEEGQDDKDFYLRGAVGLSGDHSALESQIRQLGKALDDSRFQIQQTENIIRSKTPTGPELDTSYKGYMKLLGECSSSIDSVKRLEHKLKEEEESLPGFVNLHSTETQTAGVIDRWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIELQIKKLKELQKAVDHRKAIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLLEEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEILQDHHKQLMQIKHELLESQLRVASLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKELEKLLDVSSSQQDLSSWSSADELDTSGSVSPTSGRSTPNRQKTPRGKCSLSQPGPSVSSPHSRSTKGGSDSSLSEPGPGRSGRGFLFRVLRAALPLQLLLLLLIGLACLVPMSEEDYSCALSNNFARSFHPMLRYTNGPPPL", "length": 8797, "header": "sp|Q8NF91-1|SYNE1_HUMAN Isoform 1 of Nesprin-1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=4 CANONICAL=Q8NF91-1" }, "isoforms": [ { "isoform_ac": "A0A0C4DG40-1", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#A0A0C4DG40-1", "sequence": { "sequence": "MATSRGASRCPRDIANVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGVKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRKSMHRGSPIKLVNINSTDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSIVSSETPSPPSKRKVTTKIQGNAKKALLKWVQYTAGKQTGIEVKDFGKSWRSGVAFHSVIHAIRPELVDLETVKGRSNRENLEDAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDIHNASTDGQEDDEILPGFPSFANSVQNFKREDRVIFKEMKVWIEQFERDLTRAQMVESNLQDKYQSFKHFRVQYEMKRKQIEHLIQPLHRDGKLSLDQALVKQSWDRVTSRLFDWHIQLDKSLPAPLGTIGAWLYRAEVALREEITVQQVHEETANTIQRKLEQHKDLLQNTDAHKRAFHEIYRTRSVNGIPVPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVEQLLQNYVSFIENSKFFEQYEVTYQILKQTAEMYVKADGSVEEAENVMKFMNETTAQWRNLSVEVRSVRSMLEEVISNWDRYGNTVASLQAWLEDAEKMLNQSENAKKDFFRNLPHWIQQHTAMNDAGNFLIETCDEMVSRDLKQQLLLLNGRWRELFMEVKQYAQADEMDRMKKEYTDCVVTLSAFATEAHKKLSEPLEVSFMNVKLLIQDLEDIEQRVPVMDAQYKIITKTAHLITKESPQEEGKEMFATMSKLKEQLTKVKECYSPLLYESQQLLIPLEELEKQMTSFYDSLGKINEIITVLEREAQSSALFKQKHQELLACQENCKKTLTLIEKGSQSVQKFVTLSNVLKHFDQTRLQRQIADIHVAFQSMVKKTGDWKKHVETNSRLMKKFEESRAELEKVLRIAQEGLEEKGDPEELLRRHTEFFSQLDQRVLNAFLKACDELTDILPEQEQQGLQEAVRKLHKQWKDLQGEAPYHLLHLKIDVEKNRFLASVEECRTELDRETKLMPQEGSEKIIKEHRVFFSDKGPHHLCEKRLQLIEELCVKLPVRDPVRDTPGTCHVTLKELRAAIDSTYRKLMEDPDKWKDYTSRFSEFSSWISTNETQLKGIKGEAIDTANHGEVKRAVEEIRNGVTKRGETLSWLKSRLKVLTEVSSENEAQKQGDELAKLSSSFKALVTLLSEVEKMLSNFGDCVQYKEIVKNSLEELISGSKEVQEQAEKILDTENLFEAQQLLLHHQQKTKRISAKKRDVQQQIAQAQQGEGGLPDRGHEELRKLESTLDGLERSRERQERRIQVTLRKWERFETNKETVVRYLFQTGSSHERFLSFSSLESLSSELEQTKEFSKRTESIAVQAENLVKEASEIPLGPQNKQLLQQQAKSIKEQVKKLEDTLEEDIKTMEMVKTKWDHFGSNFETLSVWITEKEKELNALETSSSAMDMQISQIKVTIQEIESKLSSIVGLEEEAQSFAQFVTTGESARIKAKLTQIRRYGEELREHAQCLEGTILGHLSQQQKFEENLRKIQQSVSEFEDKLAVPIKICSSATETYKVLQEHMDLCQALESLSSAITAFSASARKVVNRDSCVQEAAALQQQYEDILRRAKERQTALENLLAHWQRLEKELSSFLTWLERGEAKASSPEMDISADRVKVEGELQLIQALQNEVVSQASFYSKLLQLKESLFSVASKDDVKMMKLHLEQLDERWRDLPQIINKRINFLQSVVAEHQQFDELLLSFSVWIKLFLSELQTTSEISIMDHQVALTRHKDHAAEVESKKGELQSLQGHLAKLGSLGRAEDLHLLQGKAEDCFQLFEEASQVVERRQLALSHLAEFLQSHASLSGILRQLRQTVEATNSMNKNESDLIEKDLNDALQNAKALESAAVSLDGILSKAQYHLKIGSSEQRTSCRATADQLCGEVERIQNLLGTKQSEADALAVLKKAFQDQKEELLKSIEDIEERTDKERLKEPTRQALQQRLRVFNQLEDELNSHEHELCWLKDKAKQIAQKDVAFAPEVDREINRLEVTWDDTKRLIHENQGQCCGLIDLMREYQNLKSAVSKVLENASSVIVTRTTIKDQEDLKWAFSKHETAKNKMNYKQKDLDNFTSKGKHLLSELKKIHSSDFSLVKTDMESTVDKWLDVSEKLEENMDRLRVSLSIWDDVLSTRDEIEGWSNNCVPQMAENISNLDNHLRAEELLKEFESEVKNKALRLEELHSKVNDLKELTKNLETPPDLQFIEADLMQKLEHAKEITEVAKGTLKDFTAQSTQVEKFINDITTWFTKVEESLMNCAQNETCEALKKVKDIQKELQSQQSNISSTQENLNSLCRKYHSAELESLGRAMTGLIKKHEAVSQLCSKTQASLQESLEKHFSESMQEFQEWFLGAKAAAKESSDRTGDSKVLEAKLHDLQNILDSVSDGQSKLDAVTQEGQTLYAHLSKQIVSSIQEQITKANEEFQAFLKQCLKDKQALQDCASELGSFEDQHRKLNLWIHEMEERFNTENLGESKQHIPEKKNEVHKVEMFLGELLAARESLDKLSQRGQLLSEEGHGAGQEGRLCSQLLTSHQNLLRMTKEKLRSCQVALQEHEALEEALQSMWFWVKAIQDRLACAESTLGSKDTLEKRLSQIQDILLMKGEGEVKLNMAIGKGEQALRSSNKEGQRVIQTQLETLKEVWADIMSSSVHAQSTLESVISQWNDYVERKNQLEQWMESVDQKIEHPLQPQPGLKEKFVLLDHLQSILSEAEDHTRALHRLIAKSRELYEKTEDESFKDTAQEELKTQFNDIMTVAKEKMRKVEEIVKDHLMYLDAVHEFTDWLHSAKEELHRWSDMSGDSSATQKKLSKIKELIDSREIGASRLSRVESLAPEVKQNTTASGCELMHTEMQALRADWKQWEDSVFQTQSCLENLVSQMALSEQEFSGQVAQLEQALEQFSALLKTWAQQLTLLEGKNTDEEIVECWHKGQEILDALQKAEPRTEDLKSQLNELCRFSRDLSTYSGKVSGLIKEYNCLCLQASKGCQNKEQILQQRFRKAFRDFQQWLVNAKITTAKCFDIPQNISEVSTSLQKIQEFLSESENGQHKLNMMLSKGELLSTLLTKEKAKGIQAKVTAAKEDWKNFHSNLHQKESALENLKIQMKDFEVSAEPIQDWLSKTEKMVHESSNRLYDLPAKRREQQKLQSVLEEIHCYEPQLNRLKEKAQQLWEGQAASKSFRHRVSQLSSQYLALSNLTKEKVSRLDRIVAEHNQFSLGIKELQDWMTDAIHMLDSYCHPTSDKSVLDSRTLKLEALLSVKQEKEIQMKMIVTRGESVLQNTSPEGIPTIQQQLQSVKDMWASLLSAGIRCKSQLEGALSKWTSYQDGVRQFSGWMDSMEANLNESERQHAELRDKTTMLGKAKLLNEEVLSYSSLLETIEVKGAGMTEHYVTQLELQDLQERYRAIQERAKEAVTKSEKLVRLHQEYQRDLKAFEVWLGQEQEKLDQYSVLEGDAHTHETTLRDLQELQVHCAEGQALLNSVLHTREDVIPSGIPQAEDRALESLRQDWQAYQHRLSETRTQFNNVVNKLRLMEQKFQQVDEWLKTAEEKKWHEEVTAYRDEVEEVGARAQEILDESHVNSRMGCQATQLTSRYQALLLQVLEQIKFLEEEIQSLEESESSLSSYSDWYGSTHKNFKNVATKIDKVDTVMMGKKLKTLEVLLKDMEKGHSLLKSAREKGERAVKYLEEGEAERLRKEIHDHMEQLKELTSTVRKEHMTLEKGLHLAKEFSDKCKALTQWIAEYQEILHVPEEPKMELYEKKAQLSKYKSLQQTVLSHEPSVKSVREKGEALLELVQDVTLKDKIDQLQSDYQDLCSIGKAMMEEIAGFEDRLNNLQMKGDTLIGQCADHLQAKLKQNVHAHLQGTKDSYSAICSTAQRMYQSLEHELQKHVSRQDTLQQCQAWLSAVQPDLEPSPQPPLSRAEAIKQVKHFRALQEQARTYLDLLCSMCDLSNASVKTTAKDIQQTEQTIEQKLVQAQNLTQGWEEIKHLKSELWIYLQDADQQLQNMKRRHSELELNIAQNMVSQVKDFVKKLQSKQASVNTIIEKVNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNVVEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNLDDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIAEALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALSDAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDDVSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQKCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESSELHTQLAKYQNILEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQEAILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGEAVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQQLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDPLAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELSGPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLAELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQELLQLAGNGLDVESAEENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRDSGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKALVSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILEDAVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSALGMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMVETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGLYTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKLKAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELHQQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYILHQTLLEESKEIDSELEAMTEKLQYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQDAAKDMKKFEAELKKLQAALEQAQATLTSPEVGRLSLKEQLSHRQHLLSEMESLKPKVQAVQLCQSALRIPEDVVASLPLCHAALRLQEEASRLQHTAIQQCNIMQAAVVQYEQYEQEMKHLQQLIEGAHREIEDKPVATSNIQELQAQISRHEELAQKIKGYQEQIASLNSKCKMLTMKAKHATMLLTVTEVEGLAEGTEDLDGELLPTPSAHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEISSPPACRSPSPVANTDASVNQDIAYYQALSAERLQTDAAKIHPSTSASQEFYEPGLEPSATAKLGDLQRSWETLKNVISEKQRTLYEALERQQKYQDSLQSISTKMEAIELKLSESPEPGRSPESQMAEHQALMDEILMLQDEINELQSSLAEELVSESCEADPAEQLALQSTLTVLAERMSTIRMKASGKRQLLEEKLNDQLEEQRQEQALQRYRCEADELDSWLLSTKATLDTALSPPKEPMDMEAQLMDCQNMLVEIEQKVVALSELSVHNENLLLEGKAHTKDEAEQLAGKLRRLKGSLLELQRALHDKQLNMQGTAQEKEESDVDLTATQSPGVQEWLAQARTTWTQQRQSSLQQQKELEQELAEQKSLLRSVASRGEEILIQHSAAETSGDAGEKPDVLSQELGMEGEKSSAEDQMRMKWESLHQEFSTKQKLLQNVLEQEQEQVLYSRPNRLLSGVPLYKGDVPTQDKSAVTSLLDGLNQAFEEVSSQSGGAKRQSIHLEQKLYDGVSATSTWLDDVEERLFVATALLPEETETCLFNQEILAKDIKEMSEEMDKNKNLFSQAFPENGDNRDVIEDTLGCLLGRLSLLDSVVNQRCHQMKERLQQILNFQNDLKVLFTSLADNKYIILQKLANVFEQPVAEQIEAIQQAEDGLKEFDAGIIELKRRGDKLQVEQPSMQELSKLQDMYDELMMIIGSRRSGLNQNLTLKSQYERALQDLADLLETGQEKMAGDQKIIVSSKEEIQQLLDKHKEYFQGLESHMILTETLFRKIISFAVQKETQFHTELMAQASAVLKRAHKRGVELEYILETWSHLDEDQQELSRQLEVVESSIPSVGLVEENEDRLIDRITLYQHLKSSLNEYQPKLYQVLDDGKRLLISISCSDLESQLNQLGECWLSNTNKMSKELHRLETILKHWTRYQSESADLIHWLQSAKDRLEFWTQQSVTVPQELEMVRDHLNAFLEFSKEVDAQSSLKSSVLSTGNQLLRLKKVDTATLRSELSRIDSQWTDLLTNIPAVQEKLHQLQMDKLPSRHAISEVMSWISLMENVIQKDEDNIKNSIGYKAIHEYLQKYKGFKIDINCKQLTVDFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNKSWQILQGLVTEKIQLLEGLLESWSEYENNVQCLKTWFETQEKRLKQQHRIGDQASVQNALKDCQDLEDLIKAKEKEVEKIEQNGLALIQNKKEDVSSIVMSTLRELGQTWANLDHMVGQLKILLKSVLDQWSSHKVAFDKINSYLMEARYSLSRFRLLTGSLEAVQVQVDNLQNLQDDLEKQERSLQKFGSITNQLLKECHPPVTETLTNTLKEVNMRWNNLLEEIAEQLQSSKALLQLWQRYKDYSKQCASTVQQQEDRTNELLKAATNKDIADDEVATWIQDCNDLLKGLGTVKDSLFFLHELGEQLKQQVDASAASAIQSDQLSLSQHLCALEQALCKQQTSLQAGVLDYETFAKSLEALEAWIVEAEEILQGQDPSHSSDLSTIQERMEELKGQMLKFSSMAPDLDRLNELGYRLPLNDKEIKRMQNLNRHWSLISSQTTERFSKLQSFLLQHQTFLEKCETWMEFLVQTEQKLAVEISGNYQHLLEQQRAHELFQAEMFSRQQILHSIIIDGQRLLEQGQVDDRDEFNLKLTLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYREMAEKLRKWLVEVSYLPMSGLGSVPIPLQQARTLFDEVQFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELAEIQEKWKSASMRLEEQKKKLAFLLKDWEKCEKGIADSLEKLRTFKKKLSQSLPDHHEELHAEQMRCKELENAVGSWTDDLTQLSLLKDTLSAYISADDISILNERVELLQRQWEELCHQLSLRRQQIGERLNEWAVFSEKNKELCEWLTQMESKVSQNGDILIEEMIEKLKKDYQEEIAIAQENKIQLQQMGERLAKASHESKASEIEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVYDSCNSEEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTVAKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELRRYCQEVFGRVERYHKKLIRLPLPDDEHDLSDRELELEDSAALSDLHWHDRSADSLLSPQPSSNLSLSLAQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESAMSRALPSEDEEGQDDKDFYLRGAVGLSDVMIPESPEAYVKLTENAIKNTSGDHSALESQIRQLGKALDDSRFQIQQTENIIRSKTPTGPELDTSYKGYMKLLGECSSSIDSVKRLEHKLKEEEESLPGFVNLHSTETQTAGVIDRWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIELQIKKLKELQKAVDHRKAIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLLEEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEILQDHHKQLMQIKHELLESQLRVASLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKELEKLLDVSSSQQDLSSWSSADELDTSGSVSPTSGRSTPNRQKTPRGKCSLSQPGPSVSSPHSRSTKGGSDSSLSEPGPGRSGRGFLFRVLRAALPLQLLLLLLIGLACLVPMSEEDYSCALSNNFARSFHPMLRYTNGPPPL", "length": 8749, "header": "tr|A0A0C4DG40-1|A0A0C4DG40_HUMAN Computationally mapped isoform of Nesprin-1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=1 CANONICAL=Q8NF91-1" }, "locus": { "chromosome": "6", "start_pos": 152628331, "end_pos": 152122439, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000423061.6", "url": "https://www.ensembl.org/id/ENST00000423061.6" }, { "database": "Ensembl Peptide", "id": "ENSP00000396024.1", "url": "https://www.ensembl.org/id/ENSP00000396024.1" } ] } }, { "isoform_ac": "A0A0C4DH48-1", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#A0A0C4DH48-1", "sequence": { "sequence": "KELIDSREIGASRLSRVESLAPEVKQNTTASGCELMHTEMQALRADWKQWEDSVFQTQSCLENLVSQMALSEQEFSGQVAQLEQALEQFSALLKTWAQQLTLLEGKNTDEEIVECWHKGQEILDALQKAEPRTEDLKSQLNELCRFSRDLSTYSGKVSGLIKEYNCLCLQASKGCQNKEQILQQRFRKAFRDFQQWLVNAKITTAKCFDIPQNISEVSTSLQKIQEFLSESENGQHKLNMMLSKGELLSTLLTKEKAKGIQAKVTAAKEDWKNFHSNLHQKESALENLKIQMKDFEVSAEPIQDWLSKTEKMVHESSNRLYDLPAKRREQQKLQSVLEEIHCYEPQLNRLKEKAQQLWEGQAASKSFRHRVSQLSSQYLALSNLTKEKVSRLDRIVAEHNQFSLGIKELQDWMTDAIHMLDSYCHPTSDKSVLDSRTLKLEVCIFTQKYLQPTEFVFLKISRLHPPGVMMSHSLHDKSQMLCECNAVCLGCTCQRIPESSDPGCFPKNKIK", "length": 511, "header": "tr|A0A0C4DH48-1|SYNE1_HUMAN Computationally mapped isoform of Nesprin-1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=2 CANONICAL=Q8NF91-1" }, "locus": { "chromosome": "6", "start_pos": 152385676, "end_pos": 152367008, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000454018.7", "url": "https://www.ensembl.org/id/ENST00000454018.7" }, { "database": "Ensembl Peptide", "id": "ENSP00000390858.4", "url": "https://www.ensembl.org/id/ENSP00000390858.4" } ] } }, { "isoform_ac": "A0A5F9ZH00-1", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#A0A5F9ZH00-1", "sequence": { "sequence": "MATSRGASRCPRDIANVMQRLQGIGNQVAVLLGFTF", "length": 36, "header": "tr|A0A5F9ZH00-1|A0A5F9ZH00_HUMAN Computationally mapped isoform of Spectrin repeat containing nuclear envelope protein 1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=4 SV=1 CANONICAL=Q8NF91-1" }, "locus": { "chromosome": "6", "start_pos": 152628331, "end_pos": 152542200, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000673163.1", "url": "https://www.ensembl.org/id/ENST00000673163.1" }, { "database": "Ensembl Peptide", "id": "ENSP00000499934.1", "url": "https://www.ensembl.org/id/ENSP00000499934.1" } ] } }, { "isoform_ac": "A0A5F9ZH86-1", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#A0A5F9ZH86-1", "sequence": { "sequence": "XIEQIIAQGEQLIEKSEPLDAAIIEEELDELRRYCQEVFGRVERYHKKLIRLPPSSNLSLSLAQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESAMSRALPSEDEEGQDDKDFYLRGAVGLSGDHSALESQIRQLGKALDDSRFQIQQTENIIRSKTPTGPELDTSYKGYMKLLGECSSSIDSVKRLEHKLKEEEESLPGFVNLHSTETQTAGVIDRWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIELQIKKLKELQKAVDHRKAIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLLEEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEILQDHHKQLMQIKHELLESQLRVASLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKELEKLLDVSSSQQDLSSWSSADELDTSGSVSPTSGRSTPNRQKTVHKRWLRFLPF", "length": 510, "header": "tr|A0A5F9ZH86-1|A0A5F9ZH86_HUMAN Computationally mapped isoform of Spectrin repeat containing nuclear envelope protein 1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=1 CANONICAL=Q8NF91-1" }, "locus": { "chromosome": "6", "start_pos": 152149634, "end_pos": 152122643, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000672154.1", "url": "https://www.ensembl.org/id/ENST00000672154.1" }, { "database": "Ensembl Peptide", "id": "ENSP00000500128.1", "url": "https://www.ensembl.org/id/ENSP00000500128.1" } ] } }, { "isoform_ac": "A0A5F9ZH87-1", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#A0A5F9ZH87-1", "sequence": { "sequence": "SLKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELRRYCQEVFGRVERYHKKLIRLPLPDDEHDLSDRELELEDSAALSDLHWHDRSADSLLSPQPSSNLSLSLAQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESAMSRALPSEDEEGQDDKDFYLRGAVGLSGDHSALESQIRQLGKALDDSRFQIQQTENIIRSKTPTGPELDTSYKGYMKLLGECSSSIDSVKRLEHKLKEEEESLPGFVNLHSTETQTAGVIDRWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIELQIKKLKELQKAVDHRKAIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLLEEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEILQDHHKQLMVRCVNSGSLQLFLAGLHFIYRK", "length": 542, "header": "tr|A0A5F9ZH87-1|A0A5F9ZH87_HUMAN Computationally mapped isoform of Spectrin repeat containing nuclear envelope protein 1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=1 CANONICAL=Q8NF91-1" }, "locus": { "chromosome": "6", "start_pos": 152152042, "end_pos": 152135038, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000673451.1", "url": "https://www.ensembl.org/id/ENST00000673451.1" }, { "database": "Ensembl Peptide", "id": "ENSP00000500189.1", "url": "https://www.ensembl.org/id/ENSP00000500189.1" } ] } }, { "isoform_ac": "A0A5F9ZHB2-1", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#A0A5F9ZHB2-1", "sequence": { "sequence": "XVIYTVAKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELRRYCQEVFGRVERYHKKLIRLPLPDDEHDLSDRELELEDSAALSDLHWHDRSADSLLSPQPSSNLSLSLAQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESAMSRALPSEDEEGQDDKDFYLRGAVGLSGVIDRWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIELQIKKLKELQKAVDHRKAIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLLEEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEILQDHHKQLMQIKHELLESQLRVASLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKELEKLLDVSSSQQDLSSWSSADELDTSGSVSPTSGRSTPNRQKTVHKRWLRFLPF", "length": 591, "header": "tr|A0A5F9ZHB2-1|A0A5F9ZHB2_HUMAN Computationally mapped isoform of Spectrin repeat containing nuclear envelope protein 1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=3 CANONICAL=Q8NF91-1" }, "locus": { "chromosome": "6", "start_pos": 152154934, "end_pos": 152122642, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000673173.1", "url": "https://www.ensembl.org/id/ENST00000673173.1" }, { "database": "Ensembl Peptide", "id": "ENSP00000500180.1", "url": "https://www.ensembl.org/id/ENSP00000500180.1" } ] } }, { "isoform_ac": "A0A5F9ZHD7-1", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#A0A5F9ZHD7-1", "sequence": { "sequence": "MIKTIYKTPGMIKDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGVKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRKSMHRGSPIKLVNINSTDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSIVSSETPSPPSKRKVTTKIQGNAKKALLKWVQYTAGKQTGIEVKDFGKSWRSGVAFHSVIHAIRPELVDLETVKGRSNRENLEDAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDIHNASTDGQEDDEILPGFPSFANSVQNFKREDRVIFKEMKVWIEQFERDLTRAQMVESNLQDKYQSFKHFRVQYEMKRKQIEHLIQPLHRDGKLSLDQALVKQSWDRVTSRLFDWHIQLDKSLPAPLGTIGAWLYRAEVALREEITVQQVHEETANTIQRKLEQHKDLLQNTDAHKRAFHEIYRTRSVNGIPVPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVEQLLQNYVSFIENSKFFEQYEVTYQILKQTAEMYVKADGSVEEAENVMKFMNETTAQWRNLSVEVRSVRSMLEEVISNWDRYGNTVASLQAWLEDAEKMLNQSENAKKDFFRNLPHWIQQHTAMNDAGNFLIETCDEMVSRDLKQQLLLLNGRWRELFMEVKQYAQADEMDRMKKEYTDCVVTLSAFATEAHKKLSEPLEVSFMNVKLLIQDLEVRGF", "length": 752, "header": "tr|A0A5F9ZHD7-1|A0A5F9ZHD7_HUMAN Computationally mapped isoform of Spectrin repeat containing nuclear envelope protein 1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=1 CANONICAL=Q8NF91-1" }, "locus": { "chromosome": "6", "start_pos": 152563170, "end_pos": 152462726, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000535896.7", "url": "https://www.ensembl.org/id/ENST00000535896.7" }, { "database": "Ensembl Peptide", "id": "ENSP00000500235.1", "url": "https://www.ensembl.org/id/ENSP00000500235.1" } ] } }, { "isoform_ac": "A0A5F9ZHE1-1", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#A0A5F9ZHE1-1", "sequence": { "sequence": "XDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELRRYCQEVFGRVERYHKKLIRLPLPDDEHDLSDRELELEDSAALSDLHWHDRSADSLLSPQPSSNLSLSLAQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESAMSRALPSEDEEGQDDKDFYLRGAVGLSGDHSALESQIRQLGKALDDSRFQIQQTENIIRSKTPTGPELDTSYKGYMKLLGECSSSIDSVKRLEHKLKEEEESLPGFVNLHSTETQTAGVIDRWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIELQIKKLKELQKAVDHRKAIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLLEEWRGLLQDALMQCQIFTGQVGRPFLNIKGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEILQDHHKQLMQIKHELLESQLRVASLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKELEKLLDVSSSQQDLSSWSSADELDTSGSVSPTSGRSTPNRQKTVHKRWLRFLPF", "length": 635, "header": "tr|A0A5F9ZHE1-1|A0A5F9ZHE1_HUMAN Computationally mapped isoform of Spectrin repeat containing nuclear envelope protein 1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=1 CANONICAL=Q8NF91-1" }, "locus": { "chromosome": "6", "start_pos": 152152005, "end_pos": 152122643, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000672169.1", "url": "https://www.ensembl.org/id/ENST00000672169.1" }, { "database": "Ensembl Peptide", "id": "ENSP00000500287.1", "url": "https://www.ensembl.org/id/ENSP00000500287.1" } ] } }, { "isoform_ac": "A0A5F9ZHI3-1", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#A0A5F9ZHI3-1", "sequence": { "sequence": "ALFKQKHQSMVKKTGDWKKHVETNSRLMKKFEESRAELEKVLRIAQEGLEEKGDPEELLRRHTEFFSQLDQRVLNAFLKACDELTDILPEQEQQGLQEAVRKLHKQWKDLQGEAPYHLLHLKIDVEKNRFLASVEECRTELDRETKLMPQEGSEKIIKEHRVFFSDKGPHHLCEKRLQLIEELCVKLPVRDPVRDTPGTCHVTLKELRAAIDSTYRKLMEDPDKWKDYTSRFSEFSSWISTNETQLKGIKGEAIDTANHGEVKRAVEEIRNGVTKRGETLSWLKSRLKVLTEVSSENEAQKQGDELAKLSSSFKALVTLLSEVEKMLSNFGDCVQYKEIVKNSLEELISGSKEVQEQAEKILDTENLFEAQQLLLHHQQKTKRISAKKRDVQQQIAQAQQGEGGLPDRGHEELRKLESTLDGLERSRERQERRIQVTLRKWERFETNKETVVRYLFQTGSSHERFLSFSSLESLSSELEQTKEFSKRTESIAVQAENLVKEASEIPLGPQNKQLLQQQAKSIKEQVKKLEDTLEEEYVIDKS", "length": 542, "header": "tr|A0A5F9ZHI3-1|A0A5F9ZHI3_HUMAN Computationally mapped isoform of Spectrin repeat containing nuclear envelope protein 1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=1 CANONICAL=Q8NF91-1" }, "locus": { "chromosome": "6", "start_pos": 152458780, "end_pos": 152435922, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000671915.1", "url": "https://www.ensembl.org/id/ENST00000671915.1" }, { "database": "Ensembl Peptide", "id": "ENSP00000500319.1", "url": "https://www.ensembl.org/id/ENSP00000500319.1" } ] } }, { "isoform_ac": "A0A5F9ZHR3-1", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#A0A5F9ZHR3-1", "sequence": { "sequence": "MIKTIYKTPGMIKDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGVKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRKSMHRGSPIKLVNINSTDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSIVSSETPSPPSKRKVTTKIQGNAKKALLKWVQYTAGKQTGIEVKDFGKSWRSGVAFHSVIHAIRPELVDLETVKGRSNRENLEDAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDIHNASTDGQEDDREDRVIFKEMKVWIEQFERDLTRAQMVESNLQDKYQSFKHFRVQYEMKRKQIEHLIQPLHRDGKLSLDQALVKQSWDRVTSRLFDWHIQLDKSLPAPLGTIGAWLYRAEVALREEITVQQVHEETANTIQRKLEQHKDLLQNTDAHKRAFHEIYRTRSVNGIPVPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVEQLLQNYVSFIENSKFFEQYEVTYQILKQTAEMYVKADGSVEEAENVMKFMNETTAQWRNLSVEVRSVRSMLEEVISNWDRYGNTVASLQAWLEDAEKMLNQSENAKKDFFRNLPHWIQQHTAMNDAGNFLIETCDEMVSRDLKQQLLLLNGRWRELFMEVKQYAQADEMDRMKKEYTDCVVTLSAFATEAHKKLSEPLEVSFMNVKLLIQDLEDIEQRVPVMDAQYKIITKTAHLITKESPQEEGKEMFATMSKLKEQLTKVKECYSPLLYESQQLLIPLEELEKQMTSFYDSLGKINEIITVLEREAQSSALFKQKHQELLACQENCKKTLTLIEKGSQSVQKFVTLSNVLKHFDQTRLQRQIADIHVAFQSMVKKTGDWKKHVETNSRLMKKFEESRAELEKVLRIAQEGLEEKGDPEELLRRHTEFFSQLDQRVLNAFLKACDELTDILPEQEQQGLQEAVRKLHKQWKDLQGEAPYHLLHLKIDVEKNRFLASVEECRTELDRETKLMPQEGSEKIIKEHRVFFSDKGPHHLCEKRLQLIEELCVKLPVRDPVRDTPGTCHVTLKELRAAIDSTYRKLMEDPDKWKDYTSRFSEFSSWISTNETQLKGIKGEAIDTANHGEVKRAVEEIRNGVTKRGETLSWLKSRLKVLTEVSSENEAQKQGDELAKLSSSFKALVTLLSEVEKMLSNFGDCVQYKEIVKNSLEELISGSKEVQEQAEKILDTENLFEAQQLLLHHQQKTKRISAKKRDVQQQIAQAQQGEGGLPDRGHEELRKLESTLDGLERSRERQERRIQVTLRKWERFETNKETVVRYLFQTGSSHERFLSFSSLESLSSELEQTKEFSKRTESIAVQAENLVKEASEIPLGPQNKQLLQQQAKSIKEQVKKLEDTLEEEYVIDKS", "length": 1424, "header": "tr|A0A5F9ZHR3-1|A0A5F9ZHR3_HUMAN Computationally mapped isoform of Spectrin repeat containing nuclear envelope protein 1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=1 CANONICAL=Q8NF91-1" }, "locus": { "chromosome": "6", "start_pos": 152563170, "end_pos": 152435922, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000672122.1", "url": "https://www.ensembl.org/id/ENST00000672122.1" }, { "database": "Ensembl Peptide", "id": "ENSP00000500559.1", "url": "https://www.ensembl.org/id/ENSP00000500559.1" } ] } }, { "isoform_ac": "A0A5F9ZI52-1", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#A0A5F9ZI52-1", "sequence": { "sequence": "MIKTIYKTPGMIKDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGVKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRKSMHRGSPIKLVNINSTDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSIVSSETPSPPSKRKVTTKIQGNAKKALLKWVQYTAGKQTGIEVKDFGKSWRSGVAFHSVIHAIRPELVDLETVKGRSNRENLEDAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDIHNASTDGQEDDEILPGFPSFANSVQNFKREDRVIFKEMKVWIEQFERDLTRAQMVESNLQDKYQSFKHFRVQYEMKRKQIEHLIQPLHRDGKLSLDQALVKQSWDRVTSRLFDWHIQLDKSLPAPLGTIGAWLYRAEVALREEITVQQVHEETANTIQRKLEQHKDLLQNTDAHKRAFHEIYRTRSVNGIPVPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVEQLLQNYVSFIENSKFFEQYEVTYQILKQTAEMYVKADGSVEEAENVMKFMNETTAQWRNLSVEVRSVRSMLEEVISNWDRYGNTVASLQAWLEDAEKMLNQSENAKKDFFRNLPHWIQQHTAMNDAGNFLIETCDEMVSRDLKQQLLLLNGRWRELFMEVKQYAQADEMDRMKKEYTDCVVTLSAFATEAHKKLSEPLEVSFMNVKLLIQDLEDIEQRVPVMDAQYKIITKTAHLITKESPQEEGKEMFATMSKLKEQLTKVKECYSPLLYESQQLLIPLEELEKQMTSFYDSLGKINEIITVLEREAQSSALFKQKHQELLACQENCKKTLTLIEKGSQSVQKFVTLSNVLKHFDQTRLQRQIADIHVAFQSMVKKTGDWKKHVETNSRLMKKFEESRAELEKVLRIAQEGLEEKGDPEELLRRHTEFFSQLDQRVLNAFLKACDELTDILPEQEQQGLQEAVRKLHKQWKDLQGEAPYHLLHLKIDVEKNRFLASVEECRTELDRETKLMPQEGSEKIIKEHRVFFSDKGPHHLCEKRLQLIEELCVKLPVRDPVRDTPGTCHVTLKELRAAIDSTYRKLMEDPDKWKDYTSRFSEFSSWISTNETQLKGIKGEAIDTANHGEVKRAVEEIRNGVTKRGETLSWLKSRLKVLTEVSSENEAQKQGDELAKLSSSFKALVTLLSEVEKMLSNFGDCVQYKEIVKNSLEELISGSKEVQEQAEKILDTENLFEAQQLLLHHQQKTKRISAKKRDVQQQIAQAQQGEGGLPDRGHEELRKLESTLDGLERSRERQERRIQVTLRKWERFETNKETVVRYLFQTGSSHERFLSFSSLESLSSELEQTKEFSKRTESIAVQAENLVKEASEIPLGPQNKQLLQQQAKSIKEQVKKLEDTLEEDIKTMEMVKTKWDHFGSNFETLSVWITEKEKELNALETSSSAMDMQISQIKVTIQEIESKLSSIVGLEEEAQSFAQFVTTGESARIKAKLTQIR", "length": 1528, "header": "tr|A0A5F9ZI52-1|A0A5F9ZI52_HUMAN Computationally mapped isoform of Spectrin repeat containing nuclear envelope protein 1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=1 CANONICAL=Q8NF91-1" }, "locus": { "chromosome": "6", "start_pos": 152563170, "end_pos": 152430581, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000673281.1", "url": "https://www.ensembl.org/id/ENST00000673281.1" }, { "database": "Ensembl Peptide", "id": "ENSP00000500893.1", "url": "https://www.ensembl.org/id/ENSP00000500893.1" } ] } }, { "isoform_ac": "F5GXQ8-1", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#F5GXQ8-1", "sequence": { "sequence": "MATSRGASRCPRDIANVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGVKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRKSMHRGSPIKLVNINSTDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSIVSSETPSPPSKRKVTTKIQGNAKKALLKWVQYTAGKQTGIEVKDFGKSWRSGVAFHSVIHAIRPELVDLETVKGRSNRENLEDAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDIHNASTDGQEDDREDRVIFKEMKVWIEQFERDLTRAQMVESNLQDKYQSFKHFRVQYEMKRKQIEHLIQPLHRDGKLSLDQALVKQSWDRVTSRLFDWHIQLDKSLPAPLGTIGAWLYRAEVALREEITVQQVHEETANTIQRKLEQHKDLLQNTDAHKRAFHEIYRTRSVNGIPVPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVEQLLQNYVSFIENSKFFEQYEVTYQILKQTAEMYVKADGSVEEAENVMKFMNETTAQWRNLSVEVRSVRSMLEEVISNWDRYGNTVASLQAWLEDAEKMLNQSENAKKDFFRNLPHWIQQHTAMNDAGNFLIETCDEMVSRDLKQQLLLLNGRWRELFMEVKQYAQADEMDRMKKEYTDCVVTLSAFATEAHKKLSEPLEVSFMNVKLLIQDLEDIEQRVPVMDAQYKIITKTAHLITKESPQEEGKEMFATMSKLKEQLTKVKECYSPLLYESQQLLIPLEELEKQMTSFYDSLGKINEIITVLEREAQSSALFKQKHQELLACQENCKKTLTLIEKGSQSVQKFVTLSNVLKHFDQTRLQRQIADIHVAFQSMVKKTGDWKKHVETNSRLMKKFEESRAELEKVLRIAQEGLEEKGDPEELLRRHTEFFSQLDQRVLNAFLKACDELTDILPEQEQQGLQEAVRKLHKQWKDLQGEAPYHLLHLKIDVEKNRFLASVEECRTELDRETKLMPQEGSEKIIKEHRVFFSDKGPHHLCEKRLQLIEELCVKLPVRDPVRDTPGTCHVTLKELRAAIDSTYRKLMEDPDKWKDYTSRFSEFSSWISTNETQLKGIKGEAIDTANHGEVKRAVEEIRNGVTKRGETLSWLKSRLKVLTEVSSENEAQKQGDELAKLSSSFKALVTLLSEVEKMLSNFGDCVQYKEIVKNSLEELISGSKEVQEQAEKILDTENLFEAQQLLLHHQQKTKRISAKKRDVQQQIAQAQQGEGGLPDRGHEELRKLESTLDGLERSRERQERRIQVTLRKWERFETNKETVVRYLFQTGSSHERFLSFSSLESLSSELEQTKEFSKRTESIAVQAENLVKEASEIPLGPQNKQLLQQQAKSIKEQVKKLEDTLEEEYVIDKS", "length": 1433, "header": "tr|F5GXQ8-1|F5GXQ8_HUMAN Computationally mapped isoform of Spectrin repeat containing nuclear envelope protein 1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=1 CANONICAL=Q8NF91-1" }, "locus": { "chromosome": "6", "start_pos": 152628331, "end_pos": 152435922, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000367248.7", "url": "https://www.ensembl.org/id/ENST00000367248.7" }, { "database": "Ensembl Peptide", "id": "ENSP00000356217.3", "url": "https://www.ensembl.org/id/ENSP00000356217.3" } ] } }, { "isoform_ac": "F5GYQ7-1", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#F5GYQ7-1", "sequence": { "sequence": "MATSRGASRCPRDIANVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGVKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRKIKLVNINSTDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSIVSSETPSPPSKRKVTTKIQGNAKKALLKWVQYTAGKQTGIEVKDFGKSWRSGVAFHSVIHAIRPELVDLETVKGRSNRENLEDAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDIHNASTDGQEDDREDRVIFKEMKVWIEQFERDLTRAQMVESNLQDKYQSFKHFRVQYEMKRKQIEHLIQPLHRDGKLSLDQALVKQSWDRVTSRLFDWHIQLDKSLPAPLGTIGAWLYRAEVALREEITVQQVHEETANTIQRKLEQHKDLLQNTDAHKRAFHEIYRTRSVNGIPVPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVEQLLQNYVSFIENSKFFEQYEVTYQILKQTAEMYVKADGSVEEAENVMKFMNETTAQWRNLSVEVRSVRSMLEEVISNWDRYGNTVASLQAWLEDA", "length": 615, "header": "tr|F5GYQ7-1|SYNE1_HUMAN Computationally mapped isoform of Nesprin-1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=1 CANONICAL=Q8NF91-1" }, "locus": { "chromosome": "6", "start_pos": 152628331, "end_pos": 152465294, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000537750.5", "url": "https://www.ensembl.org/id/ENST00000537750.5" }, { "database": "Ensembl Peptide", "id": "ENSP00000441264.1", "url": "https://www.ensembl.org/id/ENSP00000441264.1" } ] } }, { "isoform_ac": "F5GZ83-1", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#F5GZ83-1", "sequence": { "sequence": "MFPQELAQKIKGYQEQIASLNSKCKMLTMKAKHATMLLTVTEVEGLAEGTEDLDGELLPTPSAHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEISSPPACRSPSPVANTDASVNQDIAYYQALSAERLQTDAAKIHPSTSASQEFYEPGLEPSATAKLGDLQRSWETLKNVISEKQRTLYEALERQQKYQDSLQ", "length": 195, "header": "tr|F5GZ83-1|SYNE1_HUMAN Computationally mapped isoform of Nesprin-1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=1 CANONICAL=Q8NF91-1" }, "locus": { "chromosome": "6", "start_pos": 152302075, "end_pos": 152293681, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000537033.1", "url": "https://www.ensembl.org/id/ENST00000537033.1" }, { "database": "Ensembl Peptide", "id": "ENSP00000443879.1", "url": "https://www.ensembl.org/id/ENSP00000443879.1" } ] } }, { "isoform_ac": "F5H422-1", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#F5H422-1", "sequence": { "sequence": "MQFQHSVLSTSTQLLFKDLLQNTDAHKRAFHEIYRTRSVNGIPVPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVEQLLQNYVSFIENSKFFEQYEVTYQILKQTAEMYVKADGSVEEAENVMKFMNETTAQWRNLSVEVRSVRSMLEEVISNWDRYGNTVASLQAWLEDAEKMLNQSENAKKDFFRNLPHWIQQHTAMNDAGNFLIETCDEMVSRDLKQQLLLLNGRWRELFMEVKQYAQADEMDRMKKEYTDCVVTLSAFATEAHKKLSEPLEVSFMNVKLLIQDLEDIEQRVPVMDAQYKIITKTAHLITKESPQEEGKEMFATMSKLKEQLTKVKECYSPLLYESQQLLIPLEELEKQMTSFYDSLGKINEIITVLEREAQSSALFKQKHQELLACQENCKKTLTLIEKGSQSVQKFVTLSNVLKHFDQTRLQRQIADIHVAFQSMVKKTGDWKKHVETNSRLMKKFEESRAELEKVLRIAQEGLEEKGDPEELLRRHTEFFSQLDQRVLNAFLKACDELTDILPEQEQQGLQEAVRKLHKQWKVSQDRTETPCILNEGRSLSVLRSKCKRNLEIPGKSL", "length": 612, "header": "tr|F5H422-1|SYNE1_HUMAN Computationally mapped isoform of Nesprin-1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=1 CANONICAL=Q8NF91-1" }, "locus": { "chromosome": "6", "start_pos": 152472621, "end_pos": 152453478, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000495090.6", "url": "https://www.ensembl.org/id/ENST00000495090.6" }, { "database": "Ensembl Peptide", "id": "ENSP00000438508.1", "url": "https://www.ensembl.org/id/ENSP00000438508.1" } ] } }, { "isoform_ac": "F5H4Q0-1", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#F5H4Q0-1", "sequence": { "sequence": "MATSRGASRCPRDIANVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGVKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRKIKLVNINSTDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSIVSSETPSPPSKRKVTTKIQGNAKKALLKWVQYTAGKQTGIEVKDFGKSWRSGVAFHSVIHAIRPELVDLETVKGRSNRENLEDAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDIHNASTDGQEDDEILPGFPSFANSVQNFKREDRVIFKEMKVWIEQFERDLTRAQMVESNLQDKYQSFKHFRVQYEMKRKQIEHLIQPLHRDGKLSLDQALVKQSWDRVTSRLFDWHIQLDKSLPAPLGTIGAWLYRAEVALREEITVQQVHEETANTIQRKLEQHKDLLQNTDAHKRAFHEIYRTRSVNGIPVPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVEQLLQNYVSFIENSKFFEQYEVTYQILKQTAEMYVKADGSVEEAENVMKFMNETTAQWRNLSVEVRSVRSMLEEVISNWDRYGNTVASLQAWLEDAEKMLNQSENAKKDFFRNLPHWIQQHTAMNDAGNFLIETCDEMVSRDLKQQLLLLNGRWRELFMEVKQYAQADEMDRMKKEYTDCVVTLSAFATEAHKKLSEPLEVSFMNVKLLIQDLEVRGF", "length": 754, "header": "tr|F5H4Q0-1|SYNE1_HUMAN Computationally mapped isoform of Nesprin-1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=1 CANONICAL=Q8NF91-1" }, "locus": { "chromosome": "6", "start_pos": 152628331, "end_pos": 152462726, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000466159.6", "url": "https://www.ensembl.org/id/ENST00000466159.6" }, { "database": "Ensembl Peptide", "id": "ENSP00000446021.1", "url": "https://www.ensembl.org/id/ENSP00000446021.1" } ] } }, { "isoform_ac": "F5H6R8-1", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#F5H6R8-1", "sequence": { "sequence": "MFPQELAQKIKGYQEQIASLNSKCKMLTMKAKHATMLLTVTEVEGLAEGTEDLDGELLPTPSAHPSVVMDIAYYQALSAERLQTDAAKIHPSTSASQEFYEPGLEPSATAKLGDLQRSWETLKNVISEKQRTLYEALERQQKYQDSLQSISTKMEAIELKLSESPEPGRSPESQMAEHQALMDEILMLQDEINELQSSLAEELVSESCEADPAEQLALQSTLTVLAERMSTIRMKASGKRQL", "length": 242, "header": "tr|F5H6R8-1|F5H6R8_HUMAN Computationally mapped isoform of Spectrin repeat containing nuclear envelope protein 1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=1 CANONICAL=Q8NF91-1" }, "locus": { "chromosome": "6", "start_pos": 152302075, "end_pos": 152283984, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000540663.5", "url": "https://www.ensembl.org/id/ENST00000540663.5" }, { "database": "Ensembl Peptide", "id": "ENSP00000437411.1", "url": "https://www.ensembl.org/id/ENSP00000437411.1" } ] } }, { "isoform_ac": "F8WAI0-1", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#F8WAI0-1", "sequence": { "sequence": "MVVAEDLSALRMAEDSCVDADLPDCNCDVTRVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVYDSCNSEEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTVAKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELRRYCQEVFGRVERYHKKLIRLPLPDDEHDLSDRELELEDSAALSDLHWHDRSADSLLSPQPSSNLSLSLAQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESAMSRALPSEDEEGQDDKDFYLRGAVGLSDVMIPESPEAYVKLTENAIKNTSGDHSALESQIRQLGKALDDSRFQIQQTENIIRSKTPTGPELDTSYKGYMKLLGECSSSIDSVKRLEHKLKEEEESLPGFVNLHSTETQTAGVIDRWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIELQIKKLKELQKAVDHRKAIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLLEEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEILQDHHKQLMQIKHELLESQLRVASLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKELEKLLDVSSSQQDLSSWSSADELDTSGSVSPTSGRSTPNRQKTPRGKCSLSQPGPSVSSPHSRSTKGGSDSSLSEPGPGRSGRGFLFRVLRAALPLQLLLLLLIGLACLVPMSEEDYSCALSNNFARSFHPMLRYTNGPPPL", "length": 975, "header": "tr|F8WAI0-1|F8WAI0_HUMAN Computationally mapped isoform of Spectrin repeat containing nuclear envelope protein 1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=1 CANONICAL=Q8NF91-1" }, "locus": { "chromosome": "6", "start_pos": 152168204, "end_pos": 152122439, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000354674.5", "url": "https://www.ensembl.org/id/ENST00000354674.5" }, { "database": "Ensembl Peptide", "id": "ENSP00000346701.4", "url": "https://www.ensembl.org/id/ENSP00000346701.4" } ] } }, { "isoform_ac": "H0Y325-1", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#H0Y325-1", "sequence": { "sequence": "EKIEQNGLALIQNKKEDVSSIVMSTLRELGQTWANLDHMVGQLKILLKSVLDQWSSHKVAFDKINSYLMEARYSLSRFRLLTGSLEAVQVQVDNLQNLQDDLEKQERSLQKFGSITNQLLKECHPPVTETLTNTLKEVNMRWNNLLEEIAEQLQSSKALLQLWQRYKDYSKQCASTVQQQEDRTNELLKAATNKDIADDEVATWIQDCNDLLKGLGTVKDSLFFLHELGEQLKQQVDASAASAIQSDQLSLSQHLCALEQALCKQQTSLQAGVLDYETFAKSLEALEAWIVEAEEILQGQDPSHSSDLSTIQERMEELKGQMLKFSSMAPDLDRLNELGYRLPLNDKEIKRMQNLNRHWSLISSQTTERFSKLQSFLLQHQTFLEKCETWMEFLVQTEQKLAVEISGNYQHLLEQQRAHELFQAEMFSRQQILHSIIIDGQRLLEQGQVDDRDEFNLKLTLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYREMAEKLRKWLVEVSYLPMSGLGSVPIPLQQARTLFDEVQFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELAEIQEKWKSASMRLEEQKKKLAFLLKDWEKCEKGIADSLEKLRTFKKKLSQSLPDHHEELHAEQMRCKELENAVGSWTDDLTQLSLLKDTLSAYISADDISILNERVELLQRQWEELCHQLSLRRQQIGERLNEWAVFSEKNKELCEWLTQMESKVSQNGDILIEEMIEKLKKDYQEEIAIAQENKIQLQQMGERLAKASHESKASEIEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVYDSCNSEEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTVAKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELRRYCQEVFGRVERYHKKLIRLPLPDDEHDLSDRELELEDSAALSDLHWHDRSADSLLSPQPSSNLSLSLAQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESAMSRALPSEDEEGQDDKDFYLRGAVGLSDVMIPESPEAYVKLTENAIKNTSGDHSALESQIRQLGKALDDSRFQIQQTENIIRSKTPTGPELDTSYKGYMKLLGECSSSIDSVKRLEHKLKEEEESLPGFVNLHSTETQTAGVIDRWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIELQIKKLKELQKAVDHRKAIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLLEEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEILQDHHKQLMQIKHELLESQLRVASLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKELEKLLDVSSSQQDLSSWSSADELDTSGSVSPTSGRSTPNRQKTVHKRWLRFLPF", "length": 1654, "header": "tr|H0Y325-1|H0Y325_HUMAN Computationally mapped isoform of Spectrin repeat containing nuclear envelope protein 1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=1 CANONICAL=Q8NF91-1" }, "locus": { "chromosome": "6", "start_pos": 152225837, "end_pos": 152122644, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000367251.7", "url": "https://www.ensembl.org/id/ENST00000367251.7" }, { "database": "Ensembl Peptide", "id": "ENSP00000356220.3", "url": "https://www.ensembl.org/id/ENSP00000356220.3" } ] } }, { "isoform_ac": "H0Y326-1", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#H0Y326-1", "sequence": { "sequence": "ETFAKSLEALEAWIVEAEEILQGQDPSHSSDLSTIQERMEELKGQMLKFSSMAPDLDRLNELGYRLPLNDKEIKRMQNLNRHWSLISSQTTERFSKLQSFLLQHQTFLEKCETWMEFLVQTEQKLAVEISGNYQHLLEQQRAHELFQAEMFSRQQILHSIIIDGQRLLEQGQVDDRDEFNLKLTLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYREMAEKLRKWLVEVSYLPMSGLGSVPIPLQQARTLFDEVQFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELAEIQEKWKSASMRLEEQKKKLAFLLKDWEKCEKGIADSLEKLRTFKKKLSQSLPDHHEELHAEQMRCKELENAVGSWTDDLTQLSLLKDTLSAYISADDISILNERVELLQRQWEELCHQLSLRRQQIGERLNEWAVFSEKNKELCEWLTQMESKVSQNGDILIEEMIEKLKKDYQEEIAIAQENKIQLQQMGERLAKASHESKASEIEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVYDSCNSEEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTVAKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELRRYCQEVFGRVERYHKKLIRLPLPDDEHDLSDRELELEDSAALSDLHWHDRSADSLLSPQPSSNLSLSLAQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESAMSRALPSEDEEGQDDKDFYLRGAVGLSGDHSALESQIRQLGKALDDSRFQIQQTENIIRSKTPTGPELDTSYKGYMKLLGECSSSIDSVKRLEHKLKEEEESLPGFVNLHSTETQTAGVIDRWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIELQIKKLKELQKAVDHRKAIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLLEEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEILQDHHKQLMQIKHELLESQLRVASLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKELEKLLDVSSSQQDLSSWSSADELDTSGSVSPTSGRSTPNRQKTVHKRWLRFLPF", "length": 1355, "header": "tr|H0Y326-1|SYNE1_HUMAN Computationally mapped isoform of Nesprin-1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=1 CANONICAL=Q8NF91-1" }, "locus": { "chromosome": "6", "start_pos": 152218385, "end_pos": 152122644, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000367257.8", "url": "https://www.ensembl.org/id/ENST00000367257.8" }, { "database": "Ensembl Peptide", "id": "ENSP00000356226.4", "url": "https://www.ensembl.org/id/ENSP00000356226.4" } ] } }, { "isoform_ac": "H0YFT4-1", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#H0YFT4-1", "sequence": { "sequence": "XFQHSVLSTSTQLLFKDLLQNTDAHKRAFHEIYRTRSVNGIPVPPDQLEDMAERVKAEVLDH", "length": 62, "header": "tr|H0YFT4-1|SYNE1_HUMAN Computationally mapped isoform of Nesprin-1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=1 CANONICAL=Q8NF91-1" }, "locus": { "chromosome": "6", "start_pos": 152472617, "end_pos": 152471645, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000474655.6", "url": "https://www.ensembl.org/id/ENST00000474655.6" }, { "database": "Ensembl Peptide", "id": "ENSP00000440193.1", "url": "https://www.ensembl.org/id/ENSP00000440193.1" } ] } }, { "isoform_ac": "H0YGD3-1", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#H0YGD3-1", "sequence": { "sequence": "XKEKAKGIQAKVTAAKEDWKNFHSNLHQKESALENLKIQMKDFEVSAEPIQDWLSKTEKMVHESSNRLYDLPAKRREQQKLQEKVSRLDRIVAEHNQFSLGIKELQDWMTDAIHMLDSYCHPTSDKSVLDSRTLKLEVCIFTQKYLQPTEFVFLKISRLHPPGVMMSHSLHDKSQMLCECNAVCLGCTCQRIPESSDPGCFPKNKIK", "length": 207, "header": "tr|H0YGD3-1|H0YGD3_HUMAN Computationally mapped isoform of Spectrin repeat containing nuclear envelope protein 1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=1 CANONICAL=Q8NF91-1" }, "locus": { "chromosome": "6", "start_pos": 152373136, "end_pos": 152367006, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000469439.1", "url": "https://www.ensembl.org/id/ENST00000469439.1" }, { "database": "Ensembl Peptide", "id": "ENSP00000442805.1", "url": "https://www.ensembl.org/id/ENSP00000442805.1" } ] } }, { "isoform_ac": "Q5JV20-1", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#Q5JV20-1", "sequence": { "sequence": "MVVAEDLSALRMAEDSCVDADLPDCNCDVTRVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVYDSCNSEEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTVAKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELRRYCQEVFGRVERYHKKLIRLPLPDDEHDLSDRELELEDSAALSDLHWHDRSADSLLSPQPSSNLSLSLAQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESAMSRALPSEDEEGQDDKDFYLRGAVGLSGDHSALESQIRQLGKALDDSRFQIQQTENIIRSKTPTGPELDTSYKGYMKLLGECSSSIDSVKRLEHKLKEEEESLPGFVNLHSTETQTAGVIDRWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIELQIKKLKELQKAVDHRKAIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLLEEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEILQDHHKQLMQIKHELLESQLRVASLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKELEKLLDVSSSQQDLSSWSSADELDTSGSVSPTSGRSTPNRQKTPRGKCSLSQPGPSVSSPHSRSTKGGSDSSLSEPGPGRSGRGFLFRVLRAALPLQLLLLLLIGLACLVPMSEEDYSCALSNNFARSFHPMLRYTNGPPPL", "length": 952, "header": "tr|Q5JV20-1|Q5JV20_HUMAN Computationally mapped isoform of Spectrin repeat containing nuclear envelope protein 1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=1 CANONICAL=Q8NF91-1" }, "locus": { "chromosome": "6", "start_pos": 152168204, "end_pos": 152122439, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000539504.5", "url": "https://www.ensembl.org/id/ENST00000539504.5" }, { "database": "Ensembl Peptide", "id": "ENSP00000441052.1", "url": "https://www.ensembl.org/id/ENSP00000441052.1" } ] } }, { "isoform_ac": "Q8NF91-1", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#Q8NF91-1", "sequence": { "sequence": "MATSRGASRCPRDIANVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGVKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRKIKLVNINSTDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSIVSSETPSPPSKRKVTTKIQGNAKKALLKWVQYTAGKQTGIEVKDFGKSWRSGVAFHSVIHAIRPELVDLETVKGRSNRENLEDAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDIHNASTDGQEDDEILPGFPSFANSVQNFKREDRVIFKEMKVWIEQFERDLTRAQMVESNLQDKYQSFKHFRVQYEMKRKQIEHLIQPLHRDGKLSLDQALVKQSWDRVTSRLFDWHIQLDKSLPAPLGTIGAWLYRAEVALREEITVQQVHEETANTIQRKLEQHKDLLQNTDAHKRAFHEIYRTRSVNGIPVPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVEQLLQNYVSFIENSKFFEQYEVTYQILKQTAEMYVKADGSVEEAENVMKFMNETTAQWRNLSVEVRSVRSMLEEVISNWDRYGNTVASLQAWLEDAEKMLNQSENAKKDFFRNLPHWIQQHTAMNDAGNFLIETCDEMVSRDLKQQLLLLNGRWRELFMEVKQYAQADEMDRMKKEYTDCVVTLSAFATEAHKKLSEPLEVSFMNVKLLIQDLEDIEQRVPVMDAQYKIITKTAHLITKESPQEEGKEMFATMSKLKEQLTKVKECYSPLLYESQQLLIPLEELEKQMTSFYDSLGKINEIITVLEREAQSSALFKQKHQELLACQENCKKTLTLIEKGSQSVQKFVTLSNVLKHFDQTRLQRQIADIHVAFQSMVKKTGDWKKHVETNSRLMKKFEESRAELEKVLRIAQEGLEEKGDPEELLRRHTEFFSQLDQRVLNAFLKACDELTDILPEQEQQGLQEAVRKLHKQWKDLQGEAPYHLLHLKIDVEKNRFLASVEECRTELDRETKLMPQEGSEKIIKEHRVFFSDKGPHHLCEKRLQLIEELCVKLPVRDPVRDTPGTCHVTLKELRAAIDSTYRKLMEDPDKWKDYTSRFSEFSSWISTNETQLKGIKGEAIDTANHGEVKRAVEEIRNGVTKRGETLSWLKSRLKVLTEVSSENEAQKQGDELAKLSSSFKALVTLLSEVEKMLSNFGDCVQYKEIVKNSLEELISGSKEVQEQAEKILDTENLFEAQQLLLHHQQKTKRISAKKRDVQQQIAQAQQGEGGLPDRGHEELRKLESTLDGLERSRERQERRIQVTLRKWERFETNKETVVRYLFQTGSSHERFLSFSSLESLSSELEQTKEFSKRTESIAVQAENLVKEASEIPLGPQNKQLLQQQAKSIKEQVKKLEDTLEEDIKTMEMVKTKWDHFGSNFETLSVWITEKEKELNALETSSSAMDMQISQIKVTIQEIESKLSSIVGLEEEAQSFAQFVTTGESARIKAKLTQIRRYGEELREHAQCLEGTILGHLSQQQKFEENLRKIQQSVSEFEDKLAVPIKICSSATETYKVLQEHMDLCQALESLSSAITAFSASARKVVNRDSCVQEAAALQQQYEDILRRAKERQTALENLLAHWQRLEKELSSFLTWLERGEAKASSPEMDISADRVKVEGELQLIQALQNEVVSQASFYSKLLQLKESLFSVASKDDVKMMKLHLEQLDERWRDLPQIINKRINFLQSVVAEHQQFDELLLSFSVWIKLFLSELQTTSEISIMDHQVALTRHKDHAAEVESKKGELQSLQGHLAKLGSLGRAEDLHLLQGKAEDCFQLFEEASQVVERRQLALSHLAEFLQSHASLSGILRQLRQTVEATNSMNKNESDLIEKDLNDALQNAKALESAAVSLDGILSKAQYHLKIGSSEQRTSCRATADQLCGEVERIQNLLGTKQSEADALAVLKKAFQDQKEELLKSIEDIEERTDKERLKEPTRQALQQRLRVFNQLEDELNSHEHELCWLKDKAKQIAQKDVAFAPEVDREINRLEVTWDDTKRLIHENQGQCCGLIDLMREYQNLKSAVSKVLENASSVIVTRTTIKDQEDLKWAFSKHETAKNKMNYKQKDLDNFTSKGKHLLSELKKIHSSDFSLVKTDMESTVDKWLDVSEKLEENMDRLRVSLSIWDDVLSTRDEIEGWSNNCVPQMAENISNLDNHLRAEELLKEFESEVKNKALRLEELHSKVNDLKELTKNLETPPDLQFIEADLMQKLEHAKEITEVAKGTLKDFTAQSTQVEKFINDITTWFTKVEESLMNCAQNETCEALKKVKDIQKELQSQQSNISSTQENLNSLCRKYHSAELESLGRAMTGLIKKHEAVSQLCSKTQASLQESLEKHFSESMQEFQEWFLGAKAAAKESSDRTGDSKVLEAKLHDLQNILDSVSDGQSKLDAVTQEGQTLYAHLSKQIVSSIQEQITKANEEFQAFLKQCLKDKQALQDCASELGSFEDQHRKLNLWIHEMEERFNTENLGESKQHIPEKKNEVHKVEMFLGELLAARESLDKLSQRGQLLSEEGHGAGQEGRLCSQLLTSHQNLLRMTKEKLRSCQVALQEHEALEEALQSMWFWVKAIQDRLACAESTLGSKDTLEKRLSQIQDILLMKGEGEVKLNMAIGKGEQALRSSNKEGQRVIQTQLETLKEVWADIMSSSVHAQSTLESVISQWNDYVERKNQLEQWMESVDQKIEHPLQPQPGLKEKFVLLDHLQSILSEAEDHTRALHRLIAKSRELYEKTEDESFKDTAQEELKTQFNDIMTVAKEKMRKVEEIVKDHLMYLDAVHEFTDWLHSAKEELHRWSDMSGDSSATQKKLSKIKELIDSREIGASRLSRVESLAPEVKQNTTASGCELMHTEMQALRADWKQWEDSVFQTQSCLENLVSQMALSEQEFSGQVAQLEQALEQFSALLKTWAQQLTLLEGKNTDEEIVECWHKGQEILDALQKAEPRTEDLKSQLNELCRFSRDLSTYSGKVSGLIKEYNCLCLQASKGCQNKEQILQQRFRKAFRDFQQWLVNAKITTAKCFDIPQNISEVSTSLQKIQEFLSESENGQHKLNMMLSKGELLSTLLTKEKAKGIQAKVTAAKEDWKNFHSNLHQKESALENLKIQMKDFEVSAEPIQDWLSKTEKMVHESSNRLYDLPAKRREQQKLQSVLEEIHCYEPQLNRLKEKAQQLWEGQAASKSFRHRVSQLSSQYLALSNLTKEKVSRLDRIVAEHNQFSLGIKELQDWMTDAIHMLDSYCHPTSDKSVLDSRTLKLEALLSVKQEKEIQMKMIVTRGESVLQNTSPEGIPTIQQQLQSVKDMWASLLSAGIRCKSQLEGALSKWTSYQDGVRQFSGWMDSMEANLNESERQHAELRDKTTMLGKAKLLNEEVLSYSSLLETIEVKGAGMTEHYVTQLELQDLQERYRAIQERAKEAVTKSEKLVRLHQEYQRDLKAFEVWLGQEQEKLDQYSVLEGDAHTHETTLRDLQELQVHCAEGQALLNSVLHTREDVIPSGIPQAEDRALESLRQDWQAYQHRLSETRTQFNNVVNKLRLMEQKFQQVDEWLKTAEEKVSPRTRRQSNRATKEIQLHQMKKWHEEVTAYRDEVEEVGARAQEILDESHVNSRMGCQATQLTSRYQALLLQVLEQIKFLEEEIQSLEESESSLSSYSDWYGSTHKNFKNVATKIDKVDTVMMGKKLKTLEVLLKDMEKGHSLLKSAREKGERAVKYLEEGEAERLRKEIHDHMEQLKELTSTVRKEHMTLEKGLHLAKEFSDKCKALTQWIAEYQEILHVPEEPKMELYEKKAQLSKYKSLQQTVLSHEPSVKSVREKGEALLELVQDVTLKDKIDQLQSDYQDLCSIGKEHVFSLEAKVKDHEDYNSELQEVEKWLLQMSGRLVAPDLLETSSLETITQQLAHHKAMMEEIAGFEDRLNNLQMKGDTLIGQCADHLQAKLKQNVHAHLQGTKDSYSAICSTAQRMYQSLEHELQKHVSRQDTLQQCQAWLSAVQPDLEPSPQPPLSRAEAIKQVKHFRALQEQARTYLDLLCSMCDLSNASVKTTAKDIQQTEQTIEQKLVQAQNLTQGWEEIKHLKSELWIYLQDADQQLQNMKRRHSELELNIAQNMVSQVKDFVKKLQSKQASVNTIIEKVNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNVVEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNLDDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIAEALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALSDAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDDVSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQKCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESSELHTQLAKYQNILEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQEAILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGEAVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQQLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDPLAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELSGPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLAELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQELLQLAGNGLDVESAEENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRDSGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKALVSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILEDAVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSALGMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMVETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGLYTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKLKAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELHQQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYILHQTLLEESKEIDSELEAMTEKLQYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQDAAKDMKKFEAELKKLQAALEQAQATLTSPEVGRLSLKEQLSHRQHLLSEMESLKPKVQAVQLCQSALRIPEDVVASLPLCHAALRLQEEASRLQHTAIQQCNIMQEAVVQYEQYEQEMKHLQQLIEGAHREIEDKPVATSNIQELQAQISRHEELAQKIKGYQEQIASLNSKCKMLTMKAKHATMLLTVTEVEGLAEGTEDLDGELLPTPSAHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEISSPPACRSPSPVANTDASVNQDIAYYQALSAERLQTDAAKIHPSTSASQEFYEPGLEPSATAKLGDLQRSWETLKNVISEKQRTLYEALERQQKYQDSLQSISTKMEAIELKLSESPEPGRSPESQMAEHQALMDEILMLQDEINELQSSLAEELVSESCEADPAEQLALQSTLTVLAERMSTIRMKASGKRQLLEEKLNDQLEEQRQEQALQRYRCEADELDSWLLSTKATLDTALSPPKEPMDMEAQLMDCQNMLVEIEQKVVALSELSVHNENLLLEGKAHTKDEAEQLAGKLRRLKGSLLELQRALHDKQLNMQGTAQEKEESDVDLTATQSPGVQEWLAQARTTWTQQRQSSLQQQKELEQELAEQKSLLRSVASRGEEILIQHSAAETSGDAGEKPDVLSQELGMEGEKSSAEDQMRMKWESLHQEFSTKQKLLQNVLEQEQEQVLYSRPNRLLSGVPLYKGDVPTQDKSAVTSLLDGLNQAFEEVSSQSGGAKRQSIHLEQKLYDGVSATSTWLDDVEERLFVATALLPEETETCLFNQEILAKDIKEMSEEMDKNKNLFSQAFPENGDNRDVIEDTLGCLLGRLSLLDSVVNQRCHQMKERLQQILNFQNDLKVLFTSLADNKYIILQKLANVFEQPVAEQIEAIQQAEDGLKEFDAGIIELKRRGDKLQVEQPSMQELSKLQDMYDELMMIIGSRRSGLNQNLTLKSQYERALQDLADLLETGQEKMAGDQKIIVSSKEEIQQLLDKHKEYFQGLESHMILTETLFRKIISFAVQKETQFHTELMAQASAVLKRAHKRGVELEYILETWSHLDEDQQELSRQLEVVESSIPSVGLVEENEDRLIDRITLYQHLKSSLNEYQPKLYQVLDDGKRLLISISCSDLESQLNQLGECWLSNTNKMSKELHRLETILKHWTRYQSESADLIHWLQSAKDRLEFWTQQSVTVPQELEMVRDHLNAFLEFSKEVDAQSSLKSSVLSTGNQLLRLKKVDTATLRSELSRIDSQWTDLLTNIPAVQEKLHQLQMDKLPSRHAISEVMSWISLMENVIQKDEDNIKNSIGYKAIHEYLQKYKGFKIDINCKQLTVDFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNKSWQILQGLVTEKIQLLEGLLESWSEYENNVQCLKTWFETQEKRLKQQHRIGDQASVQNALKDCQDLEDLIKAKEKEVEKIEQNGLALIQNKKEDVSSIVMSTLRELGQTWANLDHMVGQLKILLKSVLDQWSSHKVAFDKINSYLMEARYSLSRFRLLTGSLEAVQVQVDNLQNLQDDLEKQERSLQKFGSITNQLLKECHPPVTETLTNTLKEVNMRWNNLLEEIAEQLQSSKALLQLWQRYKDYSKQCASTVQQQEDRTNELLKAATNKDIADDEVATWIQDCNDLLKGLGTVKDSLFFLHELGEQLKQQVDASAASAIQSDQLSLSQHLCALEQALCKQQTSLQAGVLDYETFAKSLEALEAWIVEAEEILQGQDPSHSSDLSTIQERMEELKGQMLKFSSMAPDLDRLNELGYRLPLNDKEIKRMQNLNRHWSLISSQTTERFSKLQSFLLQHQTFLEKCETWMEFLVQTEQKLAVEISGNYQHLLEQQRAHELFQAEMFSRQQILHSIIIDGQRLLEQGQVDDRDEFNLKLTLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYREMAEKLRKWLVEVSYLPMSGLGSVPIPLQQARTLFDEVQFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELAEIQEKWKSASMRLEEQKKKLAFLLKDWEKCEKGIADSLEKLRTFKKKLSQSLPDHHEELHAEQMRCKELENAVGSWTDDLTQLSLLKDTLSAYISADDISILNERVELLQRQWEELCHQLSLRRQQIGERLNEWAVFSEKNKELCEWLTQMESKVSQNGDILIEEMIEKLKKDYQEEIAIAQENKIQLQQMGERLAKASHESKASEIEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVYDSCNSEEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTVAKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELRRYCQEVFGRVERYHKKLIRLPLPDDEHDLSDRELELEDSAALSDLHWHDRSADSLLSPQPSSNLSLSLAQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESAMSRALPSEDEEGQDDKDFYLRGAVGLSGDHSALESQIRQLGKALDDSRFQIQQTENIIRSKTPTGPELDTSYKGYMKLLGECSSSIDSVKRLEHKLKEEEESLPGFVNLHSTETQTAGVIDRWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIELQIKKLKELQKAVDHRKAIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLLEEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEILQDHHKQLMQIKHELLESQLRVASLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKELEKLLDVSSSQQDLSSWSSADELDTSGSVSPTSGRSTPNRQKTPRGKCSLSQPGPSVSSPHSRSTKGGSDSSLSEPGPGRSGRGFLFRVLRAALPLQLLLLLLIGLACLVPMSEEDYSCALSNNFARSFHPMLRYTNGPPPL", "length": 8797, "header": "sp|Q8NF91-1|SYNE1_HUMAN Isoform 1 of Nesprin-1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=4 CANONICAL=Q8NF91-1" }, "locus": { "chromosome": "6", "start_pos": 152628331, "end_pos": 152122439, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000367255.10", "url": "https://www.ensembl.org/id/ENST00000367255.10" }, { "database": "Ensembl Peptide", "id": "ENSP00000356224.5", "url": "https://www.ensembl.org/id/ENSP00000356224.5" } ] } }, { "isoform_ac": "Q8NF91-10", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#Q8NF91-10", "sequence": { "sequence": "MATSRGASRCPRDIANVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGVKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRKIKLVNINSTDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSIVSSETPSPPSKRKVTTKIQGNAKKALLKWVQYTAGKQTGIEVKDFGKSWRSGVAFHSVIHAIRPELVDLETVKGRSNRENLEDAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDIHNASTDGQEDDREDRVIFKEMKVWIEQFERDLTRAQMVESNLQDKYQSFKHFRVQYEMKRKQIEHLIQPLHRDGKLSLDQALVKQSWDRVTSRLFDWHIQLDKSLPAPLGTIGAWLYRAEVALREEITVQQVHEETANTIQRKLEQHKDLLQNTDAHKRAFHEIYRTRSVNGIPVPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVEQLLQNYVSFIENSKFFEQYEVTYQILKQTAEMYVKADGSVEEAENVMKFMNETTAQWRNLSVEVRSVRSMLEEVISNWDRYGNTVASLQAWLEDAEKMLNQSENAKKDFFRNLPHWIQQHTAMNDAGNFLIETCDEMVSRDLKQQLLLLNGRWRELFMEVKQYAQADEMDRMKKEYTDCVVTLSAFATEAHKKLSEPLEVSFMNVKLLIQDLEDIEQRVPVMDAQYKIITKTAHLITKESPQEEGKEMFATMSKLKEQLTKVKECYSPLLYESQQLLIPLEELEKQMTSFYDSLGKINEIITVLEREAQSSALFKQKHQELLACQENCKKTLTLIEKGSQSVQKFVTLSNVLKHFDQTRLQRQIADIHVAFQSMVKKTGDWKKHVETNSRLMKKFEESRAELEKVLRIAQEGLEEKGDPEELLRRHTEFFSQLDQRVLNAFLKACDELTDILPEQEQQGLQEAVRKLHKQWKDLQGEAPYHLLHLKIDVEKNRFLASVEECRTELDRETKLMPQEGSEKIIKEHRVFFSDKGPHHLCEKRLQLIEELCVKLPVRDPVRDTPGTCHVTLKELRAAIDSTYRKLMEDPDKWKDYTSRFSEFSSWISTNETQLKGIKGEAIDTANHGEVKRAVEEIRNGVTKRGETLSWLKSRLKVLTEVSSENEAQKQGDELAKLSSSFKALVTLLSEVEKMLSNFGDCVQYKEIVKNSLEELISGSKEVQEQAEKILDTENLFEAQQLLLHHQQKTKRISAKKRDVQQQIAQAQQGEGGLPDRGHEELRKLESTLDGLERSRERQERRIQVTLRKWERFETNKETVVRYLFQTGSSHERFLSFSSLESLSSELEQTKEFSKRTESIAVQAENLVKEASEIPLGPQNKQLLQQQAKSIKEQVKKLEDTLEEDIKTMEMVKTKWDHFGSNFETLSVWITEKEKELNALETSSSAMDMQISQIKVTIQEIESKLSSIVGLEEEAQSFAQFVTTGESARIKAKLTQIRRYGEELREHAQCLEGTILGHLSQQQKFEENLRKIQQSVSEFEDKLAVPIKICSSATETYKVLQEHMDLCQALESLSSAITAFSASARKVVNRDSCVQEAAALQQQYEDILRRAKERQTALENLLAHWQRLEKELSSFLTWLERGEAKASSPEMDISADRVKVEGELQLIQALQNEVVSQASFYSKLLQLKESLFSVASKDDVKMMKLHLEQLDERWRDLPQIINKRINFLQSVVAEHQQFDELLLSFSVWIKLFLSELQTTSEISIMDHQVALTRHKDHAAEVESKKGELQSLQGHLAKLGSLGRAEDLHLLQGKAEDCFQLFEEASQVVERRQLALSHLAEFLQSHASLSGILRQLRQTVEATNSMNKNESDLIEKDLNDALQNAKALESAAVSLDGILSKAQYHLKIGSSEQRTSCRATADQLCGEVERIQNLLGTKQSEADALAVLKKAFQDQKEELLKSIEDIEERTDKERLKEPTRQALQQRLRVFNQLEDELNSHEHELCWLKDKAKQIAQKDVAFAPEVDREINRLEVTWDDTKRLIHENQGQCCGLIDLMREYQNLKSAVSKVLENASSVIVTRTTIKDQEDLKWAFSKHETAKNKMNYKQKDLDNFTSKGKHLLSELKKIHSSDFSLVKTDMESTVDKWLDVSEKLEENMDRLRVSLSIWDDVLSTRDEIEGWSNNCVPQMAENISNLDNHLRAEELLKEFESEVKNKALRLEELHSKVNDLKELTKNLETPPDLQFIEADLMQKLEHAKEITEVAKGTLKDFTAQSTQVEKFINDITTWFTKVEESLMNCAQNETCEALKKVKDIQKELQSQQSNISSTQENLNSLCRKYHSAELESLGRAMTGLIKKHEAVSQLCSKTQASLQESLEKHFSESMQEFQEWFLGAKAAAKESSDRTGDSKVLEAKLHDLQNILDSVSDGQSKLDAVTQEGQTLYAHLSKQIVSSIQEQITKANEEFQAFLKQCLKDKQALQDCASELGSFEDQHRKLNLWIHEMEERFNTENLGESKQHIPEKKNEVHKVEMFLGELLAARESLDKLSQRGQLLSEEGHGAGQEGRLCSQLLTSHQNLLRMTKEKLRSCQVALQEHEALEEALQSMWFWVKAIQDRLACAESTLGSKDTLEKRLSQIQDILLMKGEGEVKLNMAIGKGEQALRSSNKEGQRVIQTQLETLKEVWADIMSSSVHAQSTLESVISQWNDYVERKNQLEQWMESVDQKIEHPLQPQPGLKEKFVLLDHLQSILSEAEDHTRALHRLIAKSRELYEKTEDESFKDTAQEELKTQFNDIMTVAKEKMRKVEEIVKDHLMYLDAVHEFTDWLHSAKEELHRWSDMSGDSSATQKKLSKIKELIDSREIGASRLSRVESLAPEVKQNTTASGCELMHTEMQALRADWKQWEDSVFQTQSCLENLVSQMALSEQEFSGQVAQLEQALEQFSALLKTWAQQLTLLEGKNTDEEIVECWHKGQEILDALQKAEPRTEDLKSQLNELCRFSRDLSTYSGKVSGLIKEYNW", "length": 3032, "header": "sp|Q8NF91-10|SYNE1_HUMAN Isoform 10 of Nesprin-1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=4 CANONICAL=Q8NF91-1" }, "locus": {} }, { "isoform_ac": "Q8NF91-11", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#Q8NF91-11", "sequence": { "sequence": "MRLEEQKKKLAFLLKDWEKCEKGIADSLEKLRTFKKKLSQSLPDHHEELHAEQMRCKELENAVGSWTDDLTQLSLLKDTLSAYISADDISILNERVELLQRQWEELCHQLSLRRQQIGERLNEWAVFSEKNKELCEWLTQMESKVSQNGDILIEEMIEKLKKDYQEEIAIAQENKIQLQQMGERLAKASHESKASEIEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVYDSCNSEEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTVAKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELRRYCQEVFGRVERYHKKLIRLPLPDDEHDLSDRELELEDSAALSDLHWHDRSADSLLSPQPSSNLSLSLAQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESAMSRALPSEDEEGQDDKDFYLRGAVGLSGDHSALESQIRQLGKALDDSRFQIQQTENIIRSKTPTGPELDTSYKGYMKLLGECSSSIDSVKRLEHKLKEEEESLPGFVNLHSTETQTAGVIDRWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIELQIKKLKELQKAVDHRKAIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLLEEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEILQDHHKQLMQIKHELLESQLRVASLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKELEKLLDVSSSQQDLSSWSSADELDTSGSVSPTSGRSTPNRQKTPRGKCSLSQPGPSVSSPHSRSTKGGSDSSLSEPGPGRSGRGFLFRVLRAALPLQLLLLLLIGLACLVPMSEEDYSCALSNNFARSFHPMLRYTNGPPPL", "length": 1139, "header": "sp|Q8NF91-11|SYNE1_HUMAN Isoform 11 of Nesprin-1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=4 CANONICAL=Q8NF91-1" }, "locus": {} }, { "isoform_ac": "Q8NF91-12", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#Q8NF91-12", "sequence": { "sequence": "MHTEMQALRADWKQWEDSVFQTQSCLENLVSQMALSEQEFSGQVAQLEQALEQFSALLKTWAQQLTLLEGKNTDEEIVECWHKGQEILDALQKAEPRTEDLKSQLNELCRFSRDLSTYSGKVSGLIKEYNCLCLQASKGCQNKEQILQQRFRKAFRDFQQWLVNAKITTAKCFDIPQNISEVSTSLQKIQEFLSESENGQHKLNMMLSKGELLSTLLTKEKAKGIQAKVTAAKEDWKNFHSNLHQKESALENLKIQMKDFEVSAEPIQDWLSKTEKMVHESSNRLYDLPAKRREQQKLQSVLEEIHCYEPQLNRLKEKAQQLWEGQAASKSFRHRVSQLSSQYLALSNLTKEKVSRLDRIVAEHNQFSLGIKELQDWMTDAIHMLDSYCHPTSDKSVLDSRTLKLEVCIFTQKYLQPTEFVFLKISRLHPPGVMMSHSLHDKSQMLCECNAVCLGCTCQRIPESSDPGCFPKNKIK", "length": 476, "header": "sp|Q8NF91-12|SYNE1_HUMAN Isoform 12 of Nesprin-1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=4 CANONICAL=Q8NF91-1" }, "locus": {} }, { "isoform_ac": "Q8NF91-2", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#Q8NF91-2", "sequence": { "sequence": "MELDAAVQKFLEQNGQLGKPLAKKIGKLTELHQQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYILHQTLLEESKEIDSELEAMTEKLQYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQDAAKDMKKFEAELKKLQAALEQAQATLTSPEVGRLSLKEQLSHRQHLLSEMESLKPKVQAVQLCQSALRIPEDVVASLPLCHAALRLQEEASRLQHTAIQQCNIMQEAVVQYEQYEQEMKHLQQLIEGAHREIEDKPVATSNIQELQAQISRHEELAQKIKGYQEQIASLNSKCKMLTMKAKHATMLLTVTEVEGLAEGTEDLDGELLPTPSAHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEISSPPACRSPSPVANTDASVNQDIAYYQALSAERLQTDAAKIHPSTSASQEFYEPGLEPSATAKLGDLQRSWETLKNVISEKQRTLYEALERQQKYQDSLQSISTKMEAIELKLSESPEPGRSPESQMAEHQALMDEILMLQDEINELQSSLAEELVSESCEADPAEQLALQSTLTVLAERMSTIRMKASGKRQLLEEKLNDQLEEQRQEQALQRYRCEADELDSWLLSTKATLDTALSPPKEPMDMEAQLMDCQNMLVEIEQKVVALSELSVHNENLLLEGKAHTKDEAEQLAGKLRRLKGSLLELQRALHDKQLNMQGTAQEKEESDVDLTATQSPGVQEWLAQARTTWTQQRQSSLQQQKELEQELAEQKSLLRSVASRGEEILIQHSAAETSGDAGEKPDVLSQELGMEGEKSSAEDQMRMKWESLHQEFSTKQKLLQNVLEQEQEQVLYSRPNRLLSGVPLYKGDVPTQDKSAVTSLLDGLNQAFEEVSSQSGGAKRQSIHLEQKLYDGVSATSTWLDDVEERLFVATALLPEETETCLFNQEILAKDIKEMSEEMDKNKNLFSQAFPENGDNRDVIEDTLGCLLGRLSLLDSVVNQRCHQMKERLQQILNFQNDLKVLFTSLADNKYIILQKLANVFEQPVAEQIEAIQQAEDGLKEFDAGIIELKRRGDKLQVEQPSMQELSKLQDMYDELMMIIGSRRSGLNQNLTLKSQYERALQDLADLLETGQEKMAGDQKIIVSSKEEIQQLLDKHKEYFQGLESHMILTETLFRKIISFAVQKETQFHTELMAQASAVLKRAHKRGVELEYILETWSHLDEDQQELSRQLEVVESSIPSVGLVEENEDRLIDRITLYQHLKSSLNEYQPKLYQVLDDGKRLLISISCSDLESQLNQLGECWLSNTNKMSKELHRLETILKHWTRYQSESADLIHWLQSAKDRLEFWTQQSVTVPQELEMVRDHLNAFLEFSKEVDAQSSLKSSVLSTGNQLLRLKKVDTATLRSELSRIDSQWTDLLTNIPAVQEKLHQLQMDKLPSRHAISEVMSWISLMENVIQKDEDNIKNSIGYKAIHEYLQKYKGFKIDINCKQLTVDFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNKSWQILQGLVTEKIQLLEGLLESWSEYENNVQCLKTWFETQEKRLKQQHRIGDQASVQNALKDCQDLEDLIKAKEKEVEKIEQNGLALIQNKKEDVSSIVMSTLRELGQTWANLDHMVGQLKILLKSVLDQWSSHKVAFDKINSYLMEARYSLSRFRLLTGSLEAVQVQVDNLQNLQDDLEKQERSLQKFGSITNQLLKECHPPVTETLTNTLKEVNMRWNNLLEEIAEQLQSSKALLQLWQRYKDYSKQCASTVQQQEDRTNELLKAATNKDIADDEVATWIQDCNDLLKGLGTVKDSLFFLHELGEQLKQQVDASAASAIQSDQLSLSQHLCALEQALCKQQTSLQAGVLDYETFAKSLEALEAWIVEAEEILQGQDPSHSSDLSTIQERMEELKGQMLKFSSMAPDLDRLNELGYRLPLNDKEIKRMQNLNRHWSLISSQTTERFSKLQSFLLQHQTFLEKCETWMEFLVQTEQKLAVEISGNYQHLLEQQRAHELFQAEMFSRQQILHSIIIDGQRLLEQGQVDDRDEFNLKLTLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYREMAEKLRKWLVEVSYLPMSGLGSVPIPLQQARTLFDEVQFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELAEIQEKWKSASMRLEEQKKKLAFLLKDWEKCEKGIADSLEKLRTFKKKLSQSLPDHHEELHAEQMRCKELENAVGSWTDDLTQLSLLKDTLSAYISADDISILNERVELLQRQWEELCHQLSLRRQQIGERLNEWAVFSEKNKELCEWLTQMESKVSQNGDILIEEMIEKLKKDYQEEIAIAQENKIQLQQMGERLAKASHESKASEIEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVYDSCNSEEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTVAKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELRRYCQEVFGRVERYHKKLIRLPLPDDEHDLSDRELELEDSAALSDLHWHDRSADSLLSPQPSSNLSLSLAQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESAMSRALPSEDEEGQDDKDFYLRGAVGLSGDHSALESQIRQLGKALDDSRFQIQQTENIIRSKTPTGPELDTSYKGYMKLLGECSSSIDSVKRLEHKLKEEEESLPGFVNLHSTETQTAGVIDRWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIELQIKKLKELQKAVDHRKAIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLLEEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEILQDHHKQLMQIKHELLESQLRVASLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKELEKLLDVSSSQQDLSSWSSADELDTSGSVSPTSGRSTPNRQKTPRGKCSLSQPGPSVSSPHSRSTKGGSDSSLSEPGPGRSGRGFLFRVLRAALPLQLLLLLLIGLACLVPMSEEDYSCALSNNFARSFHPMLRYTNGPPPL", "length": 3321, "header": "sp|Q8NF91-2|SYNE1_HUMAN Isoform 2 of Nesprin-1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=4 CANONICAL=Q8NF91-1" }, "locus": {} }, { "isoform_ac": "Q8NF91-3", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#Q8NF91-3", "sequence": { "sequence": "MGERLAKASHESKASEIEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVYDSCNSEEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTVAKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELRRYCQEVFGRVERYHKKLIRLPLPDDEHDLSDRELELEDSAALSDLHWHDRSADSLLSPQPSSNLSLSLAQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESAMSRALPSEDEEGQDDKDFYLRGAVGLSDVMIPESPEAYVKLTENAIKNTSGDHSALESQIRQLGKALDDSRFQIQQTENIIRSKTPTGPELDTSYKGYMKLLGECSSSIDSVKRLEHKLKEEEESLPGFVNLHSTETQTAGVIDRWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIELQIKKLKELQKAVDHRKAIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLLEEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEILQDHHKQLMQIKHELLESQLRVASLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKELEKLLDVSSSQQDLSSWSSADELDTSGSVSPTSGRSTPNRQKTPRGKCSLSQPGPSVSSPHSRSTKGGSDSSLSEPGPGRSGRGFLFRVLRAALPLQLLLLLLIGLACLVPMSEEDYSCALSNNFARSFHPMLRYTNGPPPL", "length": 982, "header": "sp|Q8NF91-3|SYNE1_HUMAN Isoform 3 of Nesprin-1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=4 CANONICAL=Q8NF91-1" }, "locus": {} }, { "isoform_ac": "Q8NF91-4", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#Q8NF91-4", "sequence": { "sequence": "MATSRGASRCPRDIANVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGVKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRKSMHRGSPIKLVNINSTDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSIVSSETPSPPSKRKVTTKIQGNAKKALLKWVQYTAGKQTGIEVKDFGKSWRSGVAFHSVIHAIRPELVDLETVKGRSNRENLEDAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDIHNASTDGQEDDEILPGFPSFANSVQNFKREDRVIFKEMKVWIEQFERDLTRAQMVESNLQDKYQSFKHFRVQYEMKRKQIEHLIQPLHRDGKLSLDQALVKQSWDRVTSRLFDWHIQLDKSLPAPLGTIGAWLYRAEVALREEITVQQVHEETANTIQRKLEQHKDLLQNTDAHKRAFHEIYRTRSVNGIPVPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVEQLLQNYVSFIENSKFFEQYEVTYQILKQTAEMYVKADGSVEEAENVMKFMNETTAQWRNLSVEVRSVRSMLEEVISNWDRYGNTVASLQAWLEDAEKMLNQSENAKKDFFRNLPHWIQQHTAMNDAGNFLIETCDEMVSRDLKQQLLLLNGRWRELFMEVKQYAQADEMDRMKKEYTDCVVTLSAFATEAHKKLSEPLEVSFMNVKLLIQDLEDIEQRVPVMDAQYKIITKTAHLITKESPQEEGKEMFATMSKLKEQLTKVKECYSPLLYESQQLLIPLEELEKQMTSFYDSLGKINEIITVLEREAQSSALFKQKHQELLACQENCKKTLTLIEKGSQSVQKFVTLSNVLKHFDQTRLQRQIADIHVAFQSMVKKTGDWKKHVETNSRLMKKFEESRAELEKVLRIAQEGLEEKGDPEELLRRHTEFFSQLDQRVLNAFLKACDELTDILPEQEQQGLQEAVRKLHKQWKDLQGEAPYHLLHLKIDVEKNRFLASVEECRTELDRETKLMPQEGSEKIIKEHRVFFSDKGPHHLCEKRLQLIEELCVKLPVRDPVRDTPGTCHVTLKELRAAIDSTYRKLMEDPDKWKDYTSRFSEFSSWISTNETQLKGIKGEAIDTANHGEVKRAVEEIRNGVTKRGETLSWLKSRLKVLTEVSSENEAQKQGDELAKLSSSFKALVTLLSEVEKMLSNFGDCVQYKEIVKNSLEELISGSKEVQEQAEKILDTENLFEAQQLLLHHQQKTKRISAKKRDVQQQIAQAQQGEGGLPDRGHEELRKLESTLDGLERSRERQERRIQVTLRKWERFETNKETVVRYLFQTGSSHERFLSFSSLESLSSELEQTKEFSKRTESIAVQAENLVKEASEIPLGPQNKQLLQQQAKSIKEQVKKLEDTLEEDIKTMEMVKTKWDHFGSNFETLSVWITEKEKELNALETSSSAMDMQISQIKVTIQEIESKLSSIVGLEEEAQSFAQFVTTGESARIKAKLTQIRRYGEELREHAQCLEGTILGHLSQQQKFEENLRKIQQSVSEFEDKLAVPIKICSSATETYKVLQEHMDLCQALESLSSAITAFSASARKVVNRDSCVQEAAALQQQYEDILRRAKERQTALENLLAHWQRLEKELSSFLTWLERGEAKASSPEMDISADRVKVEGELQLIQALQNEVVSQASFYSKLLQLKESLFSVASKDDVKMMKLHLEQLDERWRDLPQIINKRINFLQSVVAEHQQFDELLLSFSVWIKLFLSELQTTSEISIMDHQVALTRHKDHAAEVESKKGELQSLQGHLAKLGSLGRAEDLHLLQGKAEDCFQLFEEASQVVERRQLALSHLAEFLQSHASLSGILRQLRQTVEATNSMNKNESDLIEKDLNDALQNAKALESAAVSLDGILSKAQYHLKIGSSEQRTSCRATADQLCGEVERIQNLLGTKQSEADALAVLKKAFQDQKEELLKSIEDIEERTDKERLKEPTRQALQQRLRVFNQLEDELNSHEHELCWLKDKAKQIAQKDVAFAPEVDREINRLEVTWDDTKRLIHENQGQCCGLIDLMREYQNLKSAVSKVLENASSVIVTRTTIKDQEDLKWAFSKHETAKNKMNYKQKDLDNFTSKGKHLLSELKKIHSSDFSLVKTDMESTVDKWLDVSEKLEENMDRLRVSLSIWDDVLSTRDEIEGWSNNCVPQMAENISNLDNHLRAEELLKEFESEVKNKALRLEELHSKVNDLKELTKNLETPPDLQFIEADLMQKLEHAKEITEVAKGTLKDFTAQSTQVEKFINDITTWFTKVEESLMNCAQNETCEALKKVKDIQKELQSQQSNISSTQENLNSLCRKYHSAELESLGRAMTGLIKKHEAVSQLCSKTQASLQESLEKHFSESMQEFQEWFLGAKAAAKESSDRTGDSKVLEAKLHDLQNILDSVSDGQSKLDAVTQEGQTLYAHLSKQIVSSIQEQITKANEEFQAFLKQCLKDKQALQDCASELGSFEDQHRKLNLWIHEMEERFNTENLGESKQHIPEKKNEVHKVEMFLGELLAARESLDKLSQRGQLLSEEGHGAGQEGRLCSQLLTSHQNLLRMTKEKLRSCQVALQEHEALEEALQSMWFWVKAIQDRLACAESTLGSKDTLEKRLSQIQDILLMKGEGEVKLNMAIGKGEQALRSSNKEGQRVIQTQLETLKEVWADIMSSSVHAQSTLESVISQWNDYVERKNQLEQWMESVDQKIEHPLQPQPGLKEKFVLLDHLQSILSEAEDHTRALHRLIAKSRELYEKTEDESFKDTAQEELKTQFNDIMTVAKEKMRKVEEIVKDHLMYLDAVHEFTDWLHSAKEELHRWSDMSGDSSATQKKLSKIKELIDSREIGASRLSRVESLAPEVKQNTTASGCELMHTEMQALRADWKQWEDSVFQTQSCLENLVSQMALSEQEFSGQVAQLEQALEQFSALLKTWAQQLTLLEGKNTDEEIVECWHKGQEILDALQKAEPRTEDLKSQLNELCRFSRDLSTYSGKVSGLIKEYNCLCLQASKGCQNKEQILQQRFRKAFRDFQQWLVNAKITTAKCFDIPQNISEVSTSLQKIQEFLSESENGQHKLNMMLSKGELLSTLLTKEKAKGIQAKVTAAKEDWKNFHSNLHQKESALENLKIQMKDFEVSAEPIQDWLSKTEKMVHESSNRLYDLPAKRREQQKLQSVLEEIHCYEPQLNRLKEKAQQLWEGQAASKSFRHRVSQLSSQYLALSNLTKEKVSRLDRIVAEHNQFSLGIKELQDWMTDAIHMLDSYCHPTSDKSVLDSRTLKLEALLSVKQEKEIQMKMIVTRGESVLQNTSPEGIPTIQQQLQSVKDMWASLLSAGIRCKSQLEGALSKWTSYQDGVRQFSGWMDSMEANLNESERQHAELRDKTTMLGKAKLLNEEVLSYSSLLETIEVKGAGMTEHYVTQLELQDLQERYRAIQERAKEAVTKSEKLVRLHQEYQRDLKAFEVWLGQEQEKLDQYSVLEGDAHTHETTLRDLQELQVHCAEGQALLNSVLHTREDVIPSGIPQAEDRALESLRQDWQAYQHRLSETRTQFNNVVNKLRLMEQKFQQVDEWLKTAEEKKWHEEVTAYRDEVEEVGARAQEILDESHVNSRMGCQATQLTSRYQALLLQVLEQIKFLEEEIQSLEESESSLSSYSDWYGSTHKNFKNVATKIDKVDTVMMGKKLKTLEVLLKDMEKGHSLLKSAREKGERAVKYLEEGEAERLRKEIHDHMEQLKELTSTVRKEHMTLEKGLHLAKEFSDKCKALTQWIAEYQEILHVPEEPKMELYEKKAQLSKYKSLQQTVLSHEPSVKSVREKGEALLELVQDVTLKDKIDQLQSDYQDLCSIGKAMMEEIAGFEDRLNNLQMKGDTLIGQCADHLQAKLKQNVHAHLQGTKDSYSAICSTAQRMYQSLEHELQKHVSRQDTLQQCQAWLSAVQPDLEPSPQPPLSRAEAIKQVKHFRALQEQARTYLDLLCSMCDLSNASVKTTAKDIQQTEQTIEQKLVQAQNLTQGWEEIKHLKSELWIYLQDADQQLQNMKRRHSELELNIAQNMVSQVKDFVKKLQSKQASVNTIIEKVNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNVVEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNLDDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIAEALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALSDAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDDVSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQKCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESSELHTQLAKYQNILEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQEAILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGEAVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQQLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDPLAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELSGPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLAELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQELLQLAGNGLDVESAEENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRDSGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKALVSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILEDAVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSALGMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMVETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGLYTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKLKAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELHQQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYILHQTLLEESKEIDSELEAMTEKLQYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQDAAKDMKKFEAELKKLQAALEQAQATLTSPEVGRLSLKEQLSHRQHLLSEMESLKPKVQAVQLCQSALRIPEDVVASLPLCHAALRLQEEASRLQHTAIQQCNIMQEAVVQYEQYEQEMKHLQQLIEGAHREIEDKPVATSNIQELQAQISRHEELAQKIKGYQEQIASLNSKCKMLTMKAKHATMLLTVTEVEGLAEGTEDLDGELLPTPSAHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEISSPPACRSPSPVANTDASVNQDIAYYQALSAERLQTDAAKIHPSTSASQEFYEPGLEPSATAKLGDLQRSWETLKNVISEKQRTLYEALERQQKYQDSLQSISTKMEAIELKLSESPEPGRSPESQMAEHQALMDEILMLQDEINELQSSLAEELVSESCEADPAEQLALQSTLTVLAERMSTIRMKASGKRQLLEEKLNDQLEEQRQEQALQRYRCEADELDSWLLSTKATLDTALSPPKEPMDMEAQLMDCQNMLVEIEQKVVALSELSVHNENLLLEGKAHTKDEAEQLAGKLRRLKGSLLELQRALHDKQLNMQGTAQEKEESDVDLTATQSPGVQEWLAQARTTWTQQRQSSLQQQKELEQELAEQKSLLRSVASRGEEILIQHSAAETSGDAGEKPDVLSQELGMEGEKSSAEDQMRMKWESLHQEFSTKQKLLQNVLEQEQEQVLYSRPNRLLSGVPLYKGDVPTQDKSAVTSLLDGLNQAFEEVSSQSGGAKRQSIHLEQKLYDGVSATSTWLDDVEERLFVATALLPEETETCLFNQEILAKDIKEMSEEMDKNKNLFSQAFPENGDNRDVIEDTLGCLLGRLSLLDSVVNQRCHQMKERLQQILNFQNDLKVLFTSLADNKYIILQKLANVFEQPVAEQIEAIQQAEDGLKEFDAGIIELKRRGDKLQVEQPSMQELSKLQDMYDELMMIIGSRRSGLNQNLTLKSQYERALQDLADLLETGQEKMAGDQKIIVSSKEEIQQLLDKHKEYFQGLESHMILTETLFRKIISFAVQKETQFHTELMAQASAVLKRAHKRGVELEYILETWSHLDEDQQELSRQLEVVESSIPSVGLVEENEDRLIDRITLYQHLKSSLNEYQPKLYQVLDDGKRLLISISCSDLESQLNQLGECWLSNTNKMSKELHRLETILKHWTRYQSESADLIHWLQSAKDRLEFWTQQSVTVPQELEMVRDHLNAFLEFSKEVDAQSSLKSSVLSTGNQLLRLKKVDTATLRSELSRIDSQWTDLLTNIPAVQEKLHQLQMDKLPSRHAISEVMSWISLMENVIQKDEDNIKNSIGYKAIHEYLQKYKGFKIDINCKQLTVDFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNKSWQILQGLVTEKIQLLEGLLESWSEYENNVQCLKTWFETQEKRLKQQHRIGDQASVQNALKDCQDLEDLIKAKEKEVEKIEQNGLALIQNKKEDVSSIVMSTLRELGQTWANLDHMVGQLKILLKSVLDQWSSHKVAFDKINSYLMEARYSLSRFRLLTGSLEAVQVQVDNLQNLQDDLEKQERSLQKFGSITNQLLKECHPPVTETLTNTLKEVNMRWNNLLEEIAEQLQSSKALLQLWQRYKDYSKQCASTVQQQEDRTNELLKAATNKDIADDEVATWIQDCNDLLKGLGTVKDSLFFLHELGEQLKQQVDASAASAIQSDQLSLSQHLCALEQALCKQQTSLQAGVLDYETFAKSLEALEAWIVEAEEILQGQDPSHSSDLSTIQERMEELKGQMLKFSSMAPDLDRLNELGYRLPLNDKEIKRMQNLNRHWSLISSQTTERFSKLQSFLLQHQTFLEKCETWMEFLVQTEQKLAVEISGNYQHLLEQQRAHELFQAEMFSRQQILHSIIIDGQRLLEQGQVDDRDEFNLKLTLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYREMAEKLRKWLVEVSYLPMSGLGSVPIPLQQARTLFDEVQFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELAEIQEKWKSASMRLEEQKKKLAFLLKDWEKCEKGIADSLEKLRTFKKKLSQSLPDHHEELHAEQMRCKELENAVGSWTDDLTQLSLLKDTLSAYISADDISILNERVELLQRQWEELCHQLSLRRQQIGERLNEWAVFSEKNKELCEWLTQMESKVSQNGDILIEEMIEKLKKDYQEEIAIAQENKIQLQQMGERLAKASHESKASEIEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVYDSCNSEEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTVAKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELRRYCQEVFGRVERYHKKLIRLPLPDDEHDLSDRELELEDSAALSDLHWHDRSADSLLSPQPSSNLSLSLAQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESAMSRALPSEDEEGQDDKDFYLRGAVGLSDVMIPESPEAYVKLTENAIKNTSGDHSALESQIRQLGKALDDSRFQIQQTENIIRSKTPTGPELDTSYKGYMKLLGECSSSIDSVKRLEHKLKEEEESLPGFVNLHSTETQTAGVIDRWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIELQIKKLKELQKAVDHRKAIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLLEEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEILQDHHKQLMQIKHELLESQLRVASLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKELEKLLDVSSSQQDLSSWSSADELDTSGSVSPTSGRSTPNRQKTPRGKCSLSQPGPSVSSPHSRSTKGGSDSSLSEPGPGRSGRGFLFRVLRAALPLQLLLLLLIGLACLVPMSEEDYSCALSNNFARSFHPMLRYTNGPPPL", "length": 8749, "header": "sp|Q8NF91-4|SYNE1_HUMAN Isoform 4 of Nesprin-1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=4 CANONICAL=Q8NF91-1" }, "locus": {} }, { "isoform_ac": "Q8NF91-5", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#Q8NF91-5", "sequence": { "sequence": "MATSRGASRCPRDIANVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGVKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRKIKLVNINSTDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSIVSSETPSPPSKRKVTTKIQGNAKKALLKWVQYTAGKQTGIEVKDFGKSWRSGVAFHSVIHAIRPELVDLETVKGRSNRENLEDAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDIHNASTDGQEDDEILPGFPSFANSVQNFKREDRVIFKEMKVWIEQFERDLTRAQMVESNLQDKYQSFKHFRVQYEMKRKQIEHLIQPLHRDGKLSLDQALVKQSWDRVTSRLFDWHIQLDKSLPAPLGTIGAWLYRAEVALREEITVQQVHEETANTIQRKLEQHKDLLQNTDAHKRAFHEIYRTRSVNGIPVPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVEQLLQNYVSFIENSKFFEQYEVTYQILKQTAEMYVKADGSVEEAENVMKFMNETTAQWRNLSVEVRSVRSMLEEVISNWDRYGNTVASLQAWLEDAEKMLNQSENAKKDFFRNLPHWIQQHTAMNDAGNFLIETCDEMVSRDLKQQLLLLNGRWRELFMEVKQYAQADEMDRMKKEYTDCVVTLSAFATEAHKKLSEPLEVSFMNVKLLIQDLEDIEQRVPVMDAQYKIITKTAHLITKESPQEEGKEMFATMSKLKEQLTKVKECYSPLLYESQQLLIPLEELEKQMTSFYDSLGKINEIITVLEREAQSSALFKQKHQELLACQENCKKTLTLIEKGSQSVQKFVTLSNVLKHFDQTRLQRQIADIHVAFQSMVKKTGDWKKHVETNSRLMKKFEESRAELEKVLRIAQEGLEEKGDPEELLRRHTEFFSQLDQRVLNAFLKACDELTDILPEQEQQGLQEAVRKLHKQWKDLQGEAPYHLLHLKIDVEKNRFLASVEECRTELDRETKLMPQEGSEKIIKEHRVFFSDKGPHHLCEKRLQLIEELCVKLPVRDPVRDTPGTCHVTLKELRAAIDSTYRKLMEDPDKWKDYTSRFSEFSSWISTNETQLKGIKGEAIDTANHGEVKRAVEEIRNGVTKRGETLSWLKSRLKVLTEVSSENEAQKQGDELAKLSSSFKALVTLLSEVEKMLSNFGDCVQYKEIVKNSLEELISGSKEVQEQAEKILDTENLFEAQQLLLHHQQKTKRISAKKRDVQQQIAQAQQGEGGLPDRGHEELRKLESTLDGLERSRERQERRIQVTLRKWERFETNKETVVRYLFQTGSSHERFLSFSSLESLSSELEQTKEFSKRTESIAVQAENLVKEASEIPLGPQNKQLLQQQAKSIKEQVKKLEDTLEEEYVIDKS", "length": 1443, "header": "sp|Q8NF91-5|SYNE1_HUMAN Isoform 5 of Nesprin-1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=4 CANONICAL=Q8NF91-1" }, "locus": { "chromosome": "6", "start_pos": 152628331, "end_pos": 152435922, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000413186.6", "url": "https://www.ensembl.org/id/ENST00000413186.6" }, { "database": "Ensembl Peptide", "id": "ENSP00000414510.2", "url": "https://www.ensembl.org/id/ENSP00000414510.2" } ] } }, { "isoform_ac": "Q8NF91-6", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#Q8NF91-6", "sequence": { "sequence": "MATSRGASRCPRDIANVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGVKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRKIKLVNINSTDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSIVSSETPSPPSKRKVTTKIQGNAKKALLKWVQYTAGKQTGIEVKDFGKSWRSGVAFHSVIHAIRPELVDLETVKGRSNRENLEDAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDIHNASTDGQEDDEILPGFPSFANSVQNFKREDRVIFKEMKVWIEQFERDLTRAQMVESNLQDKYQSFKHFRVQYEMKRKQIEHLIQPLHRDGKLSLDQALVKQSWDRVTSRLFDWHIQLDKSLPAPLGTIGAWLYRAEVALREEITVQQVHEETANTIQRKLEQHKDLLQNTDAHKRAFHEIYRTRSVNGIPVPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVEQLLQNYVSFIENSKFFEQYEVTYQILKQTAEMYVKADGSVEEAENVMKFMNETTAQWRNLSVEVRSVRSMLEEVISNWDRYGNTVASLQAWLEDAEKMLNQSENAKKDFFRNLPHWIQQHTAMNDAGNFLIETCDEMVSRDLKQQLLLLNGRWRELFMEVKQYAQADEMDRMKKEYTDCVVTLSAFATEAHKKLSEPLEVSFMNVKLLIQDLEDIEQRVPVMDAQYKIITKTAHLITKESPQEEGKEMFATMSKLKEQLTKVKECYSPLLYESQQLLIPLEELEKQMTSFYDSLGKINEIITVLEREAQSSALFKQKHQELLACQENCKKTLTLIEKGSQSVQKFVTLSNVLKHFDQTRLQRQIADIHVAFQSMVKKTGDWKKHVETNSRLMKKFEESRAELEKVLRIAQEGLEEKGDPEELLRRHTEFFSQLDQRVLNAFLKACDELTDILPEQEQQGLQEAVRKLHKQWKDLQGEAPYHLLHLKIDVEKNRFLASVEECRTELDRETKLMPQEGSEKIIKEHRVFFSDKGPHHLCEKRLQLIEELCVKLPVRDPVRDTPGTCHVTLKELRAAIDSTYRKLMEDPDKWKDYTSRFSEFSSWISTNETQLKGIKGEAIDTANHGEVKRAVEEIRNGVTKRGETLSWLKSRLKVLTEVSSENEAQKQGDELAKLSSSFKALVTLLSEVEKMLSNFGDCVQYKEIVKNSLEELISGSKEVQEQAEKILDTENLFEAQQLLLHHQQKTKRISAKKRDVQQQIAQAQQGEGGLPDRGHEELRKLESTLDGLERSRERQERRIQVTLRKWERFETNKETVVRYLFQTGSSHERFLSFSSLESLSSELEQTKEFSKRTESIAVQAENLVKEASEIPLGPQNKQLLQQQAKSIKEQVKKLEDTLEEDIKTMEMVKTKWDHFGSNFETLSVWITEKEKELNALETSSSAMDMQISQIKVTIQEIESKLSSIVGLEEEAQSFAQFVTTGESARIKAKLTQIRRYGEELREHAQCLEGTILGHLSQQQKFEENLRKIQQSVSEFEDKLAVPIKICSSATETYKVLQEHMDLCQALESLSSAITAFSASARKVVNRDSCVQEAAALQQQYEDILRRAKERQTALENLLAHWQRLEKELSSFLTWLERGEAKASSPEMDISADRVKVEGELQLIQASSRKCEEGKNKMLFVTVTLFKIIK", "length": 1725, "header": "sp|Q8NF91-6|SYNE1_HUMAN Isoform 6 of Nesprin-1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=4 CANONICAL=Q8NF91-1" }, "locus": { "chromosome": "6", "start_pos": 152628331, "end_pos": 152427618, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENST00000367253.8", "url": "https://www.ensembl.org/id/ENST00000367253.8" }, { "database": "Ensembl Peptide", "id": "ENSP00000356222.4", "url": "https://www.ensembl.org/id/ENSP00000356222.4" } ] } }, { "isoform_ac": "Q8NF91-7", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#Q8NF91-7", "sequence": { "sequence": "MATSRGASRCPRDIANVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGVKLLALLEVLSGQKLPCEQGRRMKRIHAVANIGTALKFLEGRKIKLVNINSTDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSIVSSETPSPPSKRKVTTKIQGNAKKALLKWVQYTAGKQTGIEVKDFGKSWRSGVAFHSVIHAIRPELVDLETVKGRSNRENLEDAFTIAETELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDIHNASTDGQEDDEILPGFPSFANSVQNFKREDRVIFKEMKVWIEQFERDLTRAQMVESNLQDKYQSFKHFRVQYEMKRKQIEHLIQPLHRDGKLSLDQALVKQSWDRVTSRLFDWHIQLDKSLPAPLGTIGAWLYRAEVALREEITVQQVHEETANTIQRKLEQHKDLLQNTDAHKRAFHEIYRTRSVNGIPVPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVEQLLQNYVSFIENSKFFEQYEVTYQILKQTAEMYVKADGSVEEAENVMKFMNETTAQWRNLSVEVRSVRSMLEEVISNWDRYGNTVASLQAWLEDAEKMLNQSENAKKDFFRNLPHWIQQHTAMNDAGNFLIETCDEMVSRDLKQQLLLLNGRWRELFMEVKQYAQADEMDRMKKEYTDCVVTLSAFATEAHKKLSEPLEVSFMNVKLLIQDLEDIEQRVPVMDAQYKIITKTAHLITKESPQEEGKEMFATMSKLKEQLTKVKECYSPLLYESQQLLIPLEELEKQMTSFYDSLGKINEIITVLEREAQSSALFKQKHQELLACQENCKKTLTLIEKGSQSVQKFVTLSNVLKHFDQTRLQRQIADIHVAFQSMVKKTGDWKKHVETNSRLMKKFEESRAELEKVLRIAQEGLEEKGDPEELLRRHTEFFSQLDQRVLNAFLKACDELTDILPEQEQQGLQEAVRKLHKQWKDLQGEAPYHLLHLKIDVEKNRFLASVEECRTELDRETKLMPQEGSEKIIKEHRVFFSDKGPHHLCEKRLQLIEELCVKLPVRDPVRDTPGTCHVTLKELRAAIDSTYRKLMEDPDKWKDYTSRFSEFSSWISTNETQLKGIKGEAIDTANHGEVKRAVEEIRNGVTKRGETLSWLKSRLKVLTEVSSENEAQKQGDELAKLSSSFKALVTLLSEVEKMLSNFGDCVQYKEIVKNSLEELISGSKEVQEQAEKILDTENLFEAQQLLLHHQQKTKRISAKKRDVQQQIAQAQQGEGGLPDRGHEELRKLESTLDGLERSRERQERRIQVTLRKWERFETNKETVVRYLFQTGSSHERFLSFSSLESLSSELEQTKEFSKRTESIAVQAENLVKEASEIPLGPQNKQLLQQQAKSIKEQVKKLEDTLEEDIKTMEMVKTKWDHFGSNFETLSVWITEKEKELNALETSSSAMDMQISQIKVTIQEIESKLSSIVGLEEEAQSFAQFVTTGESARIKAKLTQIRRYGEELREHAQCLEGTILGHLSQQQKFEENLRKIQQSVSEFEDKLAVPIKICSSATETYKVLQEHMDLCQALESLSSAITAFSASARKVVNRDSCVQEAAALQQQYEDILRRAKERQTALENLLAHWQRLEKELSSFLTWLERGEAKASSPEMDISADRVKVEGELQLIQALQNEVVSQASFYSKLLQLKESLFSVASKDDVKMMKLHLEQLDERWRDLPQIINKRINFLQSVVAEHQQFDELLLSFSVWIKLFLSELQTTSEISIMDHQVALTRHKDHAAEVESKKGELQSLQGHLAKLGSLGRAEDLHLLQGKAEDCFQLFEEASQVVERRQLALSHLAEFLQSHASLSGILRQLRQTVEATNSMNKNESDLIEKDLNDALQNAKALESAAVSLDGILSKAQYHLKIGSSEQRTSCRATADQLCGEVERIQNLLGTKQSEADALAVLKKAFQDQKEELLKSIEDIEERTDKERLKEPTRQALQQRLRVFNQLEDELNSHEHELCWLKDKAKQIAQKDVAFAPEVDREINRLEVTWDDTKRLIHENQGQCCGLIDLMREYQNLKSAVSKVLENASSVIVTRTTIKDQEDLKWAFSKHETAKNKMNYKQKDLDNFTSKGKHLLSELKKIHSSDFSLVKTDMESTVDKWLDVSEKLEENMDRLRVSLSIWDDVLSTRDEIEGWSNNCVPQMAENISNLDNHLRAEELLKEFESEVKNKALRLEELHSKVNDLKELTKNLETPPDLQFIEADLMQKLEHAKEITEVAKGTLKDFTAQSTQVEKFINDITTWFTKVEESLMNCAQNETCEALKKVKDIQKELQSQQSNISSTQENLNSLCRKYHSAELESLGRAMTGLIKKHEAVSQLCSKTQASLQESLEKHFSESMQEFQEWFLGAKAAAKESSDRTGDSKVLEAKLHDLQNILDSVSDGQSKLDAVTQEGQTLYAHLSKQIVSSIQEQITKANEEFQAFLKQCLKDKQALQDCASELGSFEDQHRKLNLWIHEMEERFNTENLGESKQHIPEKKNEVHKVEMFLGELLAARESLDKLSQRGQLLSEEGHGAGQEGRLCSQLLTSHQNLLRMTKEKLRSCQVALQEHEALEEALQSMWFWVKAIQDRLACAESTLGSKDTLEKRLSQIQDILLMKGEGEVKLNMAIGKGEQALRSSNKEGQRVIQTQLETLKEVWADIMSSSVHAQSTLESVISQWNDYVERKNQLEQWMESVDQKIEHPLQPQPGLKEKFVLLDHLQSILSEAEDHTRALHRLIAKSRELYEKTEDESFKDTAQEELKTQFNDIMTVAKEKMRKVEEIVKDHLMYLDAVHEFTDWLHSAKEELHRWSDMSGDSSATQKKLSKIKELIDSREIGASRLSRVESLAPEVKQNTTASGCELMHTEMQALRADWKQWEDSVFQTQSCLENLVSQMALSEQEFSGQVAQLEQALEQFSALLKTWAQQLTLLEGKNTDEEIVECWHKGQEILDALQKAEPRTEDLKSQLNELCRFSRDLSTYSGKVSGLIKEYNCLCLQASKGCQNKEQILQQRFRKAFRDFQQWLVNAKITTAKCFDIPQNISEVSTSLQKIQEFLSESENGQHKLNMMLSKGELLSTLLTKEKAKGIQAKVTAAKEDWKNFHSNLHQKESALENLKIQMKDFEVSAEPIQDWLSKTEKMVHESSNRLYDLPAKRREQQKLQSVLEEIHCYEPQLNRLKEKAQQLWEGQAASKSFRHRVSQLSSQYLALSNLTKEKVSRLDRIVAEHNQFSLGIKELQDWMTDAIHMLDSYCHPTSDKSVLDSRTLKLEALLSVKQEKEIQMKMIVTRGESVLQNTSPEGIPTIQQQLQSVKDMWASLLSAGIRCKSQLEGALSKWTSYQDGVRQFSGWMDSMEANLNESERQHAELRDKTTMLGKAKLLNEEVLSYSSLLETIEVKGAGMTEHYVTQLELQDLQERYRAIQERAKEAVTKSEKLVRLHQEYQRDLKAFEVWLGQEQEKLDQYSVLEGDAHTHETTLRDLQELQVHCAEGQALLNSVLHTREDVIPSGIPQAEDRALESLRQDWQAYQHRLSETRTQFNNVVNKLRLMEQKFQQVDEWLKTAEEKVSPRTRRQSNRATKEIQLHQMKKWHEEVTAYRDEVEEVGARAQEILDESHVNSRMGCQATQLTSRYQALLLQVLEQIKFLEEEIQSLEESESSLSSYSDWYGSTHKNFKNVATKIDKVDTVMMGKKLKTLEVLLKDMEKGHSLLKSAREKGERAVKYLEEGEAERLRKEIHDHMEQLKELTSTVRKEHMTLEKGLHLAKEFSDKCKALTQWIAEYQEILHVPEEPKMELYEKKAQLSKYKSLQQTVLSHEPSVKSVREKGEALLELVQDVTLKDKIDQLQSDYQDLCSIGKEHVFSLEAKVKDHEDYNSELQEVEKWLLQMSGRLVAPDLLETSSLETITQQLAHHKAMMEEIAGFEDRLNNLQMKGDTLIGQCADHLQAKLKQNVHAHLQGTKDSYSAICSTAQRMYQSLEHELQKHVSRQDTLQQCQAWLSAVQPDLEPSPQPPLSRAEAIKQVKHFRALQEQARTYLDLLCSMCDLSNASVKTTAKDIQQTEQTIEQKLVQAQNLTQGWEEIKHLKSELWIYLQDADQQLQNMKRRHSELELNIAQNMVSQVKDFVKKLQSKQASVNTIIEKVNKLTKKEESPEHKEINHLNDQWLDLCRQSNNLCLQREEDLQRTRDYHDCMNVVEVFLEKFTTEWDNLARSDAESTAVHLEALKKLALALQERKYAIEDLKDQKQKMIEHLNLDDKELVKEQTSHLEQRWFQLEDLIKRKIQVSVTNLEELNVVQSRFQELMEWAEEQQPNIAEALKQSPPPDMAQNLLMDHLAICSELEAKQMLLKSLIKDADRVMADLGLNERQVIQKALSDAQSHVNCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREHICLLPDDVSKQVKTCKSAQASLKTYQNEVTGLWAQGRELMKEVTEQEKSEVLGKLQELQSVYDSVLQKCSHRLQELEKNLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNESSELHTQLAKYQNILEQSPEYENLLLTLQRTGQTILPSLNEVDHSYLSEKLNALPRQFNVIVALAKDKFYKVQEAILARKEYASLIELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGEAVDELNQKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQEHEKMCQQLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLEDLAPHLDPLAYEKARHQIQSWQGELKLLTSAIGETVTECESRMVQSIDFQTEMSRSLDWLRRVKAELSGPVYLDLNLQDIQEEIRKIQIHQEEVQSSLRIMNALSHKEKEKFTKAKELISADLEHSLAELSELDGDIQEALRTRQATLTEIYSQCQRYYQVFQAANDWLEDAQELLQLAGNGLDVESAEENLKSHMEFFSTEDQFHSNLEELHSLVATLDPLIKPTGKEDLEQKVASLELRSQRMSRDSGAQVDLLQRCTAQWHDYQKAREEVIELMNDTEKKLSEFSLLKTSSSHEAEEKLSEHKALVSVVNSFHEKIVALEEKASQLEKTGNDASKATLSRSMTTVWQRWTRLRAVAQDQEKILEDAVDEWTGFNNKVKKATEMIDQLQDKLPGSSAEKASKAELLTLLEYHDTFVLELEQQQSALGMLRQQTLSMLQDGAAPTPGEEPPLMQEITAMQDRCLNMQEKVKTNGKLVKQELKDREMVETQINSVKCWVQETKEYLGNPTIEIDAQLEELQILLTEATNHRQNIEKMAEEQKEKYLGLYTILPSELSLQLAEVALDLKIRDQIQDKIKEVEQSKATSQELSRQIQKLAKDLTTILTKLKAKTDNVVQAKTDQKVLGEELDGCNSKLMELDAAVQKFLEQNGQLGKPLAKKIGKLTELHQQTIRQAENRLSKLNQAASHLEEYNEMLELILKWIEKAKVLAHGTIAWNSASQLREQYILHQVTLGKIIFKK", "length": 5580, "header": "sp|Q8NF91-7|SYNE1_HUMAN Isoform 7 of Nesprin-1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=4 CANONICAL=Q8NF91-1" }, "locus": {} }, { "isoform_ac": "Q8NF91-8", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#Q8NF91-8", "sequence": { "sequence": "MTEKLQYLTSVYCTEKMSQQVAELGRETEELRQMIKIRLQNLQDAAKDMKKFEAELKKLQAALEQAQATLTSPEVGRLSLKEQLSHRQHLLSEMESLKPKVQAVQLCQSALRIPEDVVASLPLCHAALRLQEEASRLQHTAIQQCNIMQEAVVQYEQYEQEMKHLQQLIEGAHREIEDKPVATSNIQELQAQISRHEELAQKIKGYQEQIASLNSKCKMLTMKAKHATMLLTVTEVEGLAEGTEDLDGELLPTPSAHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEISSPPACRSPSPVANTDASVNQDIAYYQALSAERLQTDAAKIHPSTSASQEFYEPGLEPSATAKLGDLQRSWETLKNVISEKQRTLYEALERQQKYQDSLQSISTKMEAIELKLSESPEPGRSPESQMAEHQALMDEILMLQDEINELQSSLAEELVSESCEADPAEQLALQSTLTVLAERMSTIRMKASGKRQLLEEKLNDQLEEQRQEQALQRYRCEADELDSWLLSTKATLDTALSPPKEPMDMEAQLMDCQNMLVEIEQKVVALSELSVHNENLLLEGKAHTKDEAEQLAGKLRRLKGSLLELQRALHDKQLNMQGTAQEKEESDVDLTATQSPGVQEWLAQARTTWTQQRQSSLQQQKELEQELAEQKSLLRSVASRGEEILIQHSAAETSGDAGEKPDVLSQELGMEGEKSSAEDQMRMKWESLHQEFSTKQKLLQNVLEQEQEQVLYSRPNRLLSGVPLYKGDVPTQDKSAVTSLLDGLNQAFEEVSSQSGGAKRQSIHLEQKLYDGVSATSTWLDDVEERLFVATALLPEETETCLFNQEILAKDIKEMSEEMDKNKNLFSQAFPENGDNRDVIEDTLGCLLGRLSLLDSVVNQRCHQMKERLQQILNFQNDLKVLFTSLADNKYIILQKLANVFEQPVAEQIEAIQQAEDGLKEFDAGIIELKRRGDKLQVEQPSMQELSKLQDMYDELMMIIGSRRSGLNQNLTLKSQYERALQDLADLLETGQEKMAGDQKIIVSSKEEIQQLLDKHKEYFQGLESHMILTETLFRKIISFAVQKETQFHTELMAQASAVLKRAHKRGVELEYILETWSHLDEDQQELSRQLEVVESSIPSVGLVEENEDRLIDRITLYQHLKSSLNEYQPKLYQVLDDGKRLLISISCSDLESQLNQLGECWLSNTNKMSKELHRLETILKHWTRYQSESADLIHWLQSAKDRLEFWTQQSVTVPQELEMVRDHLNAFLEFSKEVDAQSSLKSSVLSTGNQLLRLKKVDTATLRSELSRIDSQWTDLLTNIPAVQEKLHQLQMDKLPSRHAISEVMSWISLMENVIQKDEDNIKNSIGYKAIHEYLQKYKGFKIDINCKQLTVDFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNKSWQILQGLVTEKIQLLEGLLESWSEYENNVQCLKTWFETQEKRLKQQHRIGDQASVQNALKDCQDLEDLIKAKEKEVEKIEQNGLALIQNKKEDVSSIVMSTLRELGQTWANLDHMVGQLKILLKSVLDQWSSHKVAFDKINSYLMEARYSLSRFRLLTGSLEAVQVQVDNLQNLQDDLEKQERSLQKFGSITNQLLKECHPPVTETLTNTLKEVNMRWNNLLEEIAEQLQSSKALLQLWQRYKDYSKQCASTVQQQEDRTNELLKAATNKDIADDEVATWIQDCNDLLKGLGTVKDSLFFLHELGEQLKQQVDASAASAIQSDQLSLSQHLCALEQALCKQQTSLQAGVLDYETFAKSLEALEAWIVEAEEILQGQDPSHSSDLSTIQERMEELKGQMLKFSSMAPDLDRLNELGYRLPLNDKEIKRMQNLNRHWSLISSQTTERFSKLQSFLLQHQTFLEKCETWMEFLVQTEQKLAVEISGNYQHLLEQQRAHELFQAEMFSRQQILHSIIIDGQRLLEQGQVDDRDEFNLKLTLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYREMAEKLRKWLVEVSYLPMSGLGSVPIPLQQARTLFDEVQFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELAEIQEKWKSASMRLEEQKKKLAFLLKDWEKCEKGIADSLEKLRTFKKKLSQSLPDHHEELHAEQMRCKELENAVGSWTDDLTQLSLLKDTLSAYISADDISILNERVELLQRQWEELCHQLSLRRQQIGERLNEWAVFSEKNKELCEWLTQMESKVSQNGDILIEEMIEKLKKDYQEEIAIAQENKIQLQQMGERLAKASHESKASEIEYKLGKVNDRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVYDSCNSEEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTVAKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELRRYCQEVFGRVERYHKKLIRLPLPDDEHDLSDRELELEDSAALSDLHWHDRSADSLLSPQPSSNLSLSLAQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESAMSRALPSEDEEGQDDKDFYLRGAVGLSGDHSALESQIRQLGKALDDSRFQIQQTENIIRSKTPTGPELDTSYKGYMKLLGECSSSIDSVKRLEHKLKEEEESLPGFVNLHSTETQTAGVIDRWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIELQIKKLKELQKAVDHRKAIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLLEEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEILQDHHKQLMQIKHELLESQLRVASLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKELEKLLDVSSSQQDLSSWSSADELDTSGSVSPTSGRSTPNRQKTPRGKCSLSQPGPSVSSPHSRSTKGGSDSSLSEPGPGRSGRGFLFRVLRAALPLQLLLLLLIGLACLVPMSEEDYSCALSNNFARSFHPMLRYTNGPPPL", "length": 3212, "header": "sp|Q8NF91-8|SYNE1_HUMAN Isoform 8 of Nesprin-1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=4 CANONICAL=Q8NF91-1" }, "locus": {} }, { "isoform_ac": "Q8NF91-9", "url": "https://www.uniprot.org/uniprotkb/Q8NF91/entry#Q8NF91-9", "sequence": { "sequence": "MVVAEDLSALRMAEDGCVDADLPDCNCDVTRARVKKLKETLVAVQQLDKNMSSLRTWLAHIESELAKPIVYDSCNSEEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKSSERTAAFPSSSGVIYTVAKEELKKFEAFQRQVHECLTQLELINKQYRRLARENRTDSACSLKQMVHEGNQRWDNLQKRVTSILRRLKHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAIIEEELDELRRYCQEVFGRVERYHKKLIRLPLPDDEHDLSDRELELEDSAALSDLHWHDRSADSLLSPQPSSNLSLSLAQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESAMSRALPSEDEEGQDDKDFYLRGAVGLSDVMIPESPEAYVKLTENAIKNTSGDHSALESQIRQLGKALDDSRFQIQQTENIIRSKTPTGPELDTSYKGYMKLLGECSSSIDSVKRLEHKLKEEEESLPGFVNLHSTETQTAGVIDRWELLQAQALSKELRMKQNLQKWQQFNSDLNSIWAWLGDTEEELEQLQRLELSTDIQTIELQIKKLKELQKAVDHRKAIILSINLCSPEFTQADSKESRDLQDRLSQMNGRWDRVCSLLEEWRGLLQDALMQCQGFHEMSHGLLLMLENIDRRKNEIVPIDSNLDAEILQDHHKQLMQIKHELLESQLRVASLQDMSCQLLVNAEGTDCLEAKEKVHVIGNRLKLLLKEVSRHIKELEKLLDVSSSQQDLSSWSSADELDTSGSVSPTSGRSTPNRQKTPRGKCSLSQPGPSVSSPHSRSTKGGSDSSLSEPGPGRSGRGFLFRVLRAALPLQLLLLLLIGLACLVPMSEEDYSCALSNNFARSFHPMLRYTNGPPPL", "length": 977, "header": "sp|Q8NF91-9|SYNE1_HUMAN Isoform 9 of Nesprin-1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=4 CANONICAL=Q8NF91-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "start_pos": 1131, "start_aa": "Ser", "end_pos": 1131, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser1131", "evidence": [ { "id": "37541260", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/37541260" }, { "id": "Q8NF91", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/Q8NF91" } ], "filter_code": "00000000000000010000.0000000.00000001000000.1000000.0100000000.110100100001111011.10000.01001" }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", 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Humphray S, Hunt A, Jones M, Lloyd C, McMurray A, Matthews L, Mercer S, Milne S, Mullikin JC, Mungall A, Plumb R, Ross M, Shownkeen R, Sims S, Waterston RH, Wilson RK, Hillier LW, McPherson JD, Marra MA, Mardis ER, Fulton LA, Chinwalla AT, Pepin KH, Gish WR, Chissoe SL, Wendl MC, Delehaunty KD, Miner TL, Delehaunty A, Kramer JB, Cook LL, Fulton RS, Johnson DL, Minx PJ, Clifton SW, Hawkins T, Branscomb E, Predki P, Richardson P, Wenning S, Slezak T, Doggett N, Cheng JF, Olsen A, Lucas S, Elkin C, Uberbacher E, Frazier M, Gibbs RA, Muzny DM, Scherer SE, Bouck JB, Sodergren EJ, Worley KC, Rives CM, Gorrell JH, Metzker ML, Naylor SL, Kucherlapati RS, Nelson DL, Weinstock GM, Sakaki Y, Fujiyama A, Hattori M, Yada T, Toyoda A, Itoh T, Kawagoe C, Watanabe H, Totoki Y, Taylor T, Weissenbach J, Heilig R, Saurin W, Artiguenave F, Brottier P, Bruls T, Pelletier E, Robert C, Wincker P, Smith DR, Doucette-Stamm L, Rubenfield M, Weinstock K, Lee HM, Dubois J, Rosenthal A, Platzer M, Nyakatura G, Taudien S, Rump A, Yang H, Yu J, Wang J, Huang G, Gu J, Hood L, Rowen L, Madan A, Qin S, Davis RW, Federspiel NA, Abola AP, Proctor MJ, Myers RM, Schmutz J, Dickson M, Grimwood J, Cox DR, Olson MV, Kaul R, Raymond C, Shimizu N, Kawasaki K, Minoshima S, Evans GA, Athanasiou M, Schultz R, Roe BA, Chen F, Pan H, Ramser J, Lehrach H, Reinhardt R, McCombie WR, de la Bastide M, Dedhia N, Blocker H, Hornischer K, Nordsiek G, Agarwala R, Aravind L, Bailey JA, Bateman A, Batzoglou S, Birney E, Bork P, Brown DG, Burge CB, Cerutti L, Chen HC, Church D, Clamp M, Copley RR, Doerks T, Eddy SR, Eichler EE, Furey TS, Galagan J, Gilbert JG, Harmon C, Hayashizaki Y, Haussler D, Hermjakob H, Hokamp K, Jang W, Johnson LS, Jones TA, Kasif S, Kaspryzk A, Kennedy S, Kent WJ, Kitts P, Koonin EV, Korf I, Kulp D, Lancet D, Lowe TM, McLysaght A, Mikkelsen T, Moran JV, Mulder N, Pollara VJ, Ponting CP, Schuler G, Schultz J, Slater G, Smit AF, Stupka E, Szustakowki J, Thierry-Mieg D, Thierry-Mieg J, Wagner L, Wallis J, Wheeler R, Williams A, Wolf YI, Wolfe KH, Yang SP, Yeh RF, Collins F, Guyer MS, Peterson J, Felsenfeld A, Wetterstrand KA, Patrinos A, Morgan MJ, de Jong P, Catanese JJ, Osoegawa K, Shizuya H, Choi S, Chen YJ, Szustakowki J", "evidence": [ { "database": "UniProtKB", "id": "F5GZ83", "url": "https://www.uniprot.org/uniprotkb/F5GZ83" } ], "reference": [ { "type": "PubMed", "id": "11237011", "url": "https://glygen.org/publication/PubMed/11237011" } ] }, { "title": "Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress.", "journal": "The Journal of biological chemistry", "date": "2001", "authors": "Ward IM, Chen J", "evidence": [ { "database": "Reactome", "id": "R-HSA-1221632", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1221632" } ], "reference": [ { "type": "PubMed", "id": "11673449", "url": "https://glygen.org/publication/PubMed/11673449" } ] }, { "title": "Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.", "journal": "Journal of cell science", "date": "2001", "authors": "Zhang Q, Skepper JN, Yang F, Davies JD, Hegyi L, Roberts RG, Weissberg PL, Ellis JA, Shanahan CM", "evidence": [ { "database": "UniProtKB", "id": "Q8NF91", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ], "reference": [ { "type": "PubMed", "id": "11792814", "url": "https://glygen.org/publication/PubMed/11792814" } ] }, { "title": "Myne-1, a spectrin repeat transmembrane protein of the myocyte inner nuclear membrane, interacts with lamin A/C.", "journal": "J. Cell Sci.", "date": "2002", "authors": "Mislow John M K, Kim Marian S, Davis Dawn Belt, McNally Elizabeth M", "evidence": [ { "database": "UniProtKB", "id": "Q8NF91", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ], "reference": [ { "type": "PubMed", "id": "11801724", "url": "https://glygen.org/publication/PubMed/11801724" } ] }, { "title": "Nesprin-1alpha self-associates and binds directly to emerin and lamin A in vitro.", "journal": "FEBS Lett.", "date": "2002", "authors": "Mislow John M K, Holaska James M, Kim Marian S, Lee Kenneth K, Segura-Totten Miriam, Wilson Katherine L, McNally Elizabeth M", "evidence": [ { "database": "UniProtKB", "id": "Q8NF91", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ], "reference": [ { "type": "PubMed", "id": "12163176", "url": "https://glygen.org/publication/PubMed/12163176" } ] }, { "title": "The nesprins are giant actin-binding proteins, orthologous to Drosophila melanogaster muscle protein MSP-300.", "journal": "Genomics", "date": "2002", "authors": "Zhang Q, Ragnauth C, Greener MJ, Shanahan CM, Roberts RG", "evidence": [ { "database": "UniProtKB", "id": "Q8NF91", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ], "reference": [ { "type": "PubMed", "id": "12408964", "url": "https://glygen.org/publication/PubMed/12408964" } ] }, { "title": "Golgi localization of Syne-1.", "journal": "Mol. Biol. Cell", "date": "2003", "authors": "Gough Lisa Lucio, Fan Jun, Chu Stephen, Winnick Shawn, Beck Kenneth A", "evidence": [ { "database": "UniProtKB", "id": "Q8NF91", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ], "reference": [ { "type": "PubMed", "id": "12808039", "url": "https://glygen.org/publication/PubMed/12808039" } ] }, { "title": "Enaptin, a giant actin-binding protein, is an element of the nuclear membrane and the actin cytoskeleton.", "journal": "Exp. Cell Res.", "date": "2004", "authors": "Padmakumar V C, Abraham Sabu, Braune Stephan, Noegel Angelika A, Tunggal Budi, Karakesisoglou Iakowos, Korenbaum Elena", "evidence": [ { "database": "UniProtKB", "id": "Q8NF91", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ], "reference": [ { "type": "PubMed", "id": "15093733", "url": "https://glygen.org/publication/PubMed/15093733" } ] }, { "title": "Cohesin component dynamics during meiotic prophase I in mammalian oocytes.", "journal": "Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology", "date": "2004", "authors": "Prieto I, Tease C, Pezzi N, Buesa JM, Ortega S, Kremer L, Martinez A, Martinez-A C, Hulten MA, Barbero JL", "evidence": [ { "database": "Reactome", "id": "R-HSA-1221632", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1221632" } ], "reference": [ { "type": "PubMed", "id": "15125634", "url": "https://glygen.org/publication/PubMed/15125634" } ] }, { "title": "Female-specific features of recombinational double-stranded DNA repair in relation to synapsis and telomere dynamics in human oocytes.", "journal": "Chromosoma", "date": "2004", "authors": "Roig I, Liebe B, Egozcue J, Cabero L, Garcia M, Scherthan H", "evidence": [ { "database": "Reactome", "id": "R-HSA-1221632", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1221632" } ], "reference": [ { "type": "PubMed", "id": "15235794", "url": "https://glygen.org/publication/PubMed/15235794" } ] }, { "title": "Identification and characterization of GSRP-56, a novel Golgi-localized spectrin repeat-containing protein.", "journal": "Exp. Cell Res.", "date": "2006", "authors": "Kobayashi Yuko, Katanosaka Yuki, Iwata Yuko, Matsuoka Masayuki, Shigekawa Munekazu, Wakabayashi Shigeo", "evidence": [ { "database": "UniProtKB", "id": "Q8NF91", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ], "reference": [ { "type": "PubMed", "id": "16875688", "url": "https://glygen.org/publication/PubMed/16875688" } ] }, { "title": "The consensus coding sequences of human breast and colorectal cancers.", "journal": "Science (New York, N.Y.)", "date": "2006", "authors": "Sjoblom T, Jones S, Wood LD, Parsons DW, Lin J, Barber TD, Mandelker D, Leary RJ, Ptak J, Silliman N, Szabo S, Buckhaults P, Farrell C, Meeh P, Markowitz SD, Willis J, Dawson D, Willson JK, Gazdar AF, Hartigan J, Wu L, Liu C, Parmigiani G, Park BH, Bachman KE, Papadopoulos N, Vogelstein B, Kinzler KW, Velculescu VE", "evidence": [ { "database": "UniProtKB", "id": "Q8NF91", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ], "reference": [ { "type": "PubMed", "id": "16959974", "url": "https://glygen.org/publication/PubMed/16959974" } ] }, { "title": "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.", "journal": "Cell", "date": "2006", "authors": "Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M", "evidence": [ { "database": "UniProtKB", "id": "Q8NF91", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" }, { "database": "iPTMnet", "id": "Q8NF91", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8NF91" } ], "reference": [ { "type": "PubMed", "id": "17081983", "url": "https://glygen.org/publication/PubMed/17081983" } ] }, { "title": "Mutations in SYNE1 lead to a newly discovered form of autosomal recessive cerebellar ataxia.", "journal": "Nat. Genet.", "date": "2007", "authors": "Gros-Louis Fran\u00e7ois, Dupr\u00e9 Nicolas, Dion Patrick, Fox Michael A, Laurent Sandra, Verreault Steve, Sanes Joshua R, Bouchard Jean-Pierre, Rouleau Guy A", "evidence": [ { "database": "UniProtKB", "id": "Q8NF91", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ], "reference": [ { "type": "PubMed", "id": "17159980", "url": "https://glygen.org/publication/PubMed/17159980" } ] }, { "title": "Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.", "journal": "Human molecular genetics", "date": "2007", "authors": "Zhang Q, Bethmann C, Worth NF, Davies JD, Wasner C, Feuer A, Ragnauth CD, Yi Q, Mellad JA, Warren DT, Wheeler MA, Ellis JA, Skepper JN, Vorgerd M, Schlotter-Weigel B, Weissberg PL, Roberts RG, Wehnert M, Shanahan CM", "evidence": [ { "database": "UniProtKB", "id": "Q8NF91", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ], "reference": [ { "type": "PubMed", "id": "17761684", "url": "https://glygen.org/publication/PubMed/17761684" } ] }, { "title": "Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness.", "journal": "Experimental cell research", "date": "2008", "authors": "Stewart-Hutchinson PJ, Hale CM, Wirtz D, Hodzic D", "evidence": [ { "database": "UniProtKB", "id": "Q8NF91", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ], "reference": [ { "type": "PubMed", "id": "18396275", "url": "https://glygen.org/publication/PubMed/18396275" } ] }, { "title": "Loss of Drop1 expression already at early tumor stages in a wide range of human carcinomas.", "journal": "Int. J. Cancer", "date": "2008", "authors": "Marm\u00e9 Alexander, Zimmermann Hans-Peter, Moldenhauer Gerhard, Schorpp-Kistner Marina, M\u00fcller Claudia, Keberlein Olga, Giersch Antje, Kretschmer J\u00fcrgen, Seib Brigitte, Spiess Eberhard, Hunziker Andreas, Merch\u00e1n Faustino, M\u00f6ller Peter, Hahn Uwe, Kurek Raffael, Marm\u00e9 Frederik, Bastert Gunther, Wallwiener Diethelm, Ponstingl Herwig", "evidence": [ { "database": "UniProtKB", "id": "Q8NF91", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ], "reference": [ { "type": "PubMed", "id": "18709643", "url": "https://glygen.org/publication/PubMed/18709643" } ] }, { "title": "ATR, BRCA1 and gammaH2AX localize to unsynapsed chromosomes at the pachytene stage in human oocytes.", "journal": "Reproductive biomedicine online", "date": "2009", "authors": "Garcia-Cruz R, Roig I, Robles P, Scherthan H, Garcia Caldes M", "evidence": [ { "database": "Reactome", "id": "R-HSA-1221632", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1221632" } ], "reference": [ { "type": "PubMed", "id": "19146767", "url": "https://glygen.org/publication/PubMed/19146767" } ] }, { "title": "Mutation of SYNE-1, encoding an essential component of the nuclear lamina, is responsible for autosomal recessive arthrogryposis.", "journal": "Hum. Mol. Genet.", "date": "2009", "authors": "Attali Ruben, Warwar Nasim, Israel Ariel, Gurt Irina, McNally Elizabeth, Puckelwartz Megan, Glick Benjamin, Nevo Yoram, Ben-Neriah Ziva, Melki Judith", "evidence": [ { "database": "UniProtKB", "id": "Q8NF91", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ], "reference": [ { "type": "PubMed", "id": "19542096", "url": "https://glygen.org/publication/PubMed/19542096" } ] }, { "title": "Dynamics of cohesin proteins REC8, STAG3, SMC1 beta and SMC3 are consistent with a role in sister chromatid cohesion during meiosis in human oocytes.", "journal": "Human reproduction (Oxford, England)", "date": "2010", "authors": "Garcia-Cruz R, Brieno MA, Roig I, Grossmann M, Velilla E, Pujol A, Cabero L, Pessarrodona A, Barbero JL, Garcia Caldes M", "evidence": [ { "database": "Reactome", "id": "R-HSA-1221632", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1221632" } ], "reference": [ { "type": "PubMed", "id": "20634189", "url": "https://glygen.org/publication/PubMed/20634189" } ] }, { "title": "Cytoskeletal interactions at the nuclear envelope mediated by nesprins.", "journal": "Int. J. Cell Biol.", "date": "2012", "authors": "Taranum Surayya, Sur Ilknur, M\u00fcller Rolf, Lu Wenshu, Rashmi R N, Munck Martina, Neumann Sascha, Karakesisoglou Iakowos, Noegel Angelika A", "evidence": [ { "database": "UniProtKB", "id": "Q8NF91", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ], "reference": [ { "type": "PubMed", "id": "22518138", "url": "https://glygen.org/publication/PubMed/22518138" } ] }, { "title": "LINC complexes form by binding of three KASH peptides to domain interfaces of trimeric SUN proteins.", "journal": "Cell", "date": "2012", "authors": "Sosa BA, Rothballer A, Kutay U, Schwartz TU", "evidence": [ { "database": "UniProtKB", "id": "Q8NF91", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ], "reference": [ { "type": "PubMed", "id": "22632968", "url": "https://glygen.org/publication/PubMed/22632968" } ] }, { "title": "The human leukocyte antigen-presented ligandome of B lymphocytes.", "journal": "Molecular & cellular proteomics : MCP", "date": "2013-07", "authors": "Hassan Chopie, Kester Michel G D, de Ru Arnoud H, Hombrink Pleun, Drijfhout Jan Wouter, Nijveen Harm, Leunissen Jack A M, Heemskerk Mirjam H M, Falkenburg J H Frederik, van Veelen Peter A", "evidence": [ { "database": "IEDB", "id": "193793", "url": "https://www.iedb.org/epitope/193793" }, { "database": "IEDB", "id": "458809", "url": "https://www.iedb.org/epitope/458809" }, { "database": "IEDB", "id": "458871", "url": "https://www.iedb.org/epitope/458871" }, { "database": "IEDB", "id": "459144", "url": "https://www.iedb.org/epitope/459144" } ], "reference": [ { "type": "PubMed", "id": "23481700", "url": "https://glygen.org/publication/PubMed/23481700" } ] }, { "title": "Large-scale modelling of the divergent spectrin repeats in nesprins: giant modular proteins.", "journal": "PLoS ONE", "date": "2013", "authors": "Autore Flavia, Pfuhl Mark, Quan Xueping, Williams Aisling, Roberts Roland G, Shanahan Catherine M, Fraternali Franca", "evidence": [ { "database": "UniProtKB", "id": "Q8NF91", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ], "reference": [ { "type": "PubMed", "id": "23671687", "url": "https://glygen.org/publication/PubMed/23671687" } ] }, { "title": "Identification of pathogenic gene variants in small families with intellectually disabled siblings by exome sequencing.", "journal": "Journal of medical genetics", "date": "2013", "authors": "Schuurs-Hoeijmakers JH, Vulto-van Silfhout AT, Vissers LE, van de Vondervoort II, van Bon BW, de Ligt J, Gilissen C, Hehir-Kwa JY, Neveling K, del Rosario M, Hira G, Reitano S, Vitello A, Failla P, Greco D, Fichera M, Galesi O, Kleefstra T, Greally MT, Ockeloen CW, Willemsen MH, Bongers EM, Janssen IM, Pfundt R, Veltman JA, Romano C, Willemsen MA, van Bokhoven H, Brunner HG, de Vries BB, de Brouwer AP", "evidence": [ { "database": "UniProtKB", "id": "Q8NF91", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ], "reference": [ { "type": "PubMed", "id": "24123876", "url": "https://glygen.org/publication/PubMed/24123876" } ] }, { "title": "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.", "journal": "Journal of proteomics", "date": "2014", "authors": "Bian Y, Song C, Cheng K, Dong M, Wang F, Huang J, Sun D, Wang L, Ye M, Zou H", "evidence": [ { "database": "UniProtKB", "id": "Q8NF91", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" }, { "database": "iPTMnet", "id": "Q8NF91", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8NF91" } ], "reference": [ { "type": "PubMed", "id": "24275569", "url": "https://glygen.org/publication/PubMed/24275569" } ] }, { "title": "Mutations in CNTNAP1 and ADCY6 are responsible for severe arthrogryposis multiplex congenita with axoglial defects.", "journal": "Human molecular genetics", "date": "2014", "authors": "Laquerriere A, Maluenda J, Camus A, Fontenas L, Dieterich K, Nolent F, Zhou J, Monnier N, Latour P, Gentil D, Heron D, Desguerres I, Landrieu P, Beneteau C, Delaporte B, Bellesme C, Baumann C, Capri Y, Goldenberg A, Lyonnet S, Bonneau D, Estournet B, Quijano-Roy S, Francannet C, Odent S, Saint-Frison MH, Sigaudy S, Figarella-Branger D, Gelot A, Mussini JM, Lacroix C, Drouin-Garraud V, Malinge MC, Attie-Bitach T, Bessieres B, Bonniere M, Encha-Razavi F, Beaufrere AM, Khung-Savatovsky S, Perez MJ, Vasiljevic A, Mercier S, Roume J, Trestard L, Saugier-Veber P, Cordier MP, Layet V, Legendre M, Vigouroux-Castera A, Lunardi J, Bayes M, Jouk PS, Rigonnot L, Granier M, Sternberg D, Warszawski J, Gut I, Gonzales M, Tawk M, Melki J", "evidence": [ { "database": "UniProtKB", "id": "Q8NF91", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ], "reference": [ { "type": "PubMed", "id": "24319099", "url": "https://glygen.org/publication/PubMed/24319099" } ] }, { "title": "Impact of genomic polymorphisms on the repertoire of human MHC class I-associated peptides.", "journal": "Nature communications", "date": "2014-04-09", "authors": "Granados Diana Paola, Sriranganadane Dev, Daouda Tariq, Zieger Antoine, Laumont C\u00e9line M, Caron-Lizotte Olivier, Boucher Genevi\u00e8ve, Hardy Marie-Pierre, Gendron Patrick, C\u00f4t\u00e9 Caroline, Lemieux S\u00e9bastien, Thibault Pierre, Perreault Claude", "evidence": [ { "database": "IEDB", "id": "213532", "url": "https://www.iedb.org/epitope/213532" } ], "reference": [ { "type": "PubMed", "id": "24714562", "url": "https://glygen.org/publication/PubMed/24714562" } ] }, { "title": "The nature and extent of contributions by defective ribosome products to the HLA peptidome.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2014-04-22", "authors": "Bourdetsky Dmitry, Schmelzer Christian E H, Admon Arie", "evidence": [ { "database": "IEDB", "id": "507011", "url": "https://www.iedb.org/epitope/507011" }, { "database": "IEDB", "id": "507176", "url": "https://www.iedb.org/epitope/507176" }, { "database": "IEDB", "id": "507325", "url": 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MCP", "date": "2015-03", "authors": "Bassani-Sternberg Michal, Pletscher-Frankild Sune, Jensen Lars Juhl, Mann Matthias", "evidence": [ { "database": "IEDB", "id": "449014", "url": "https://www.iedb.org/epitope/449014" }, { "database": "IEDB", "id": "484416", "url": "https://www.iedb.org/epitope/484416" } ], "reference": [ { "type": "PubMed", "id": "25576301", "url": "https://glygen.org/publication/PubMed/25576301" } ] }, { "title": "Exploration of peptides bound to MHC class I molecules in melanoma.", "journal": "Pigment cell & melanoma research", "date": "2015-05", "authors": "Pritchard Antonia L, Hastie Marcus L, Neller Michelle, Gorman Jeffrey J, Schmidt Chris W, Hayward Nicholas K", "evidence": [ { "database": "IEDB", "id": "449014", "url": "https://www.iedb.org/epitope/449014" }, { "database": "IEDB", "id": "484416", "url": "https://www.iedb.org/epitope/484416" }, { "database": "IEDB", "id": "545368", "url": "https://www.iedb.org/epitope/545368" }, { "database": "IEDB", "id": 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Natl. Acad. Sci. U.S.A.", "date": "2015", "authors": "Cromer MK, Choi M, Nelson-Williams C, Fonseca AL, Kunstman JW, Korah RM, Overton JD, Mane S, Kenney B, Malchoff CD, Stalberg P, Akerstrom G, Westin G, Hellman P, Carling T, Bjorklund P, Lifton RP", "evidence": [ { "database": "UniProtKB", "id": "Q8NF91", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ], "reference": [ { "type": "PubMed", "id": "25787250", "url": "https://glygen.org/publication/PubMed/25787250" } ] }, { "title": "A comprehensive analysis of peptides presented by HLA-A1.", "journal": "Tissue antigens", "date": "2015-06", "authors": "Giam K, Ayala-Perez R, Illing P T, Schittenhelm R B, Croft N P, Purcell A W, Dudek N L", "evidence": [ { "database": "IEDB", "id": "431586", "url": "https://www.iedb.org/epitope/431586" } ], "reference": [ { "type": "PubMed", "id": "25880248", "url": "https://glygen.org/publication/PubMed/25880248" } ] }, { "title": "An open-source computational and data resource to analyze digital maps of immunopeptidomes.", "journal": "eLife", "date": "2015-07-08", "authors": "Caron Etienne, Espona Lucia, Kowalewski Daniel J, Schuster Heiko, Ternette Nicola, Alp\u00edzar Ad\u00e1n, Schittenhelm Ralf B, Ramarathinam Sri H, Lindestam Arlehamn Cecilia S, Chiek Koh Ching, Gillet Ludovic C, Rabsteyn Armin, Navarro Pedro, Kim Sangtae, Lam Henry, Sturm Theo, Marcilla Miguel, Sette Alessandro, Campbell David S, Deutsch Eric W, Moritz Robert L, Purcell Anthony W, Rammensee Hans-Georg, Stevanovic Stefan, Aebersold Ruedi", "evidence": [ { "database": "IEDB", "id": "444264", "url": "https://www.iedb.org/epitope/444264" }, { "database": "IEDB", "id": "445982", "url": "https://www.iedb.org/epitope/445982" }, { "database": "IEDB", "id": "448250", "url": "https://www.iedb.org/epitope/448250" }, { "database": "IEDB", "id": "448953", "url": "https://www.iedb.org/epitope/448953" }, { "database": "IEDB", "id": "449014", "url": "https://www.iedb.org/epitope/449014" } ], "reference": [ { "type": "PubMed", 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Carcamo Ya\u00f1ez Viviana A, Mohr Christopher, Sturm Marc, Nguyen Huu-Phuc, Riess Olaf, Bauer Peter, Nahnsen Sven, Nadalin Silvio, Zieker Derek, Glatzle J\u00f6rg, Thiel Karolin, Schneiderhan-Marra Nicole, Clasen Stephan, B\u00f6sm\u00fcller Hans, Fend Falko, Kohlbacher Oliver, Gouttefangeas C\u00e9cile, Stevanovi\u0107 Stefan, K\u00f6nigsrainer Alfred, Rammensee Hans-Georg", "evidence": [ { "database": "IEDB", "id": "449014", "url": "https://www.iedb.org/epitope/449014" }, { "database": "IEDB", "id": "484416", "url": "https://www.iedb.org/epitope/484416" } ], "reference": [ { "type": "PubMed", "id": "27397612", "url": "https://glygen.org/publication/PubMed/27397612" } ] }, { "title": "Diverse HLA-I Peptide Repertoires of the APC Lines MUTZ3-Derived Immature and Mature Dendritic Cells and THP1-Derived Macrophages.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "2016-09-15", "authors": "Nyambura Lydon Wainaina, Jarmalavicius Saulius, Baleeiro Renato Brito, Walden Peter", "evidence": [ { "database": "IEDB", "id": "549485", "url": "https://www.iedb.org/epitope/549485" } ], "reference": [ { "type": "PubMed", "id": "27543614", "url": "https://glygen.org/publication/PubMed/27543614" } ] }, { "title": "Mass spectrometric analysis of the HLA class I peptidome of melanoma cell lines as a promising tool for the identification of putative tumor-associated HLA epitopes.", "journal": "Cancer immunology, immunotherapy : CII", "date": "2016-11", "authors": "Gloger Andreas, Ritz Danilo, Fugmann Tim, Neri Dario", "evidence": [ { "database": "IEDB", "id": "563790", "url": "https://www.iedb.org/epitope/563790" } ], "reference": [ { "type": "PubMed", "id": "27600516", "url": "https://glygen.org/publication/PubMed/27600516" } ] }, { "title": "Homozygous SYNE1 mutation causes congenital onset of muscular weakness with distal arthrogryposis: a genotype-phenotype correlation.", "journal": "European journal of human genetics : EJHG", "date": "2017", "authors": "Baumann M, Steichen-Gersdorf E, Krabichler B, Petersen BS, Weber U, Schmidt WM, Zschocke J, Muller T, Bittner RE, Janecke AR", "evidence": [ { "database": "UniProtKB", "id": "Q8NF91", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ], "reference": [ { "type": "PubMed", "id": "27782104", "url": "https://glygen.org/publication/PubMed/27782104" } ] }, { "title": "A large fraction of HLA class I ligands are proteasome-generated spliced peptides.", "journal": "Science (New York, N.Y.)", "date": "2016-10-21", "authors": "Liepe Juliane, Marino Fabio, Sidney John, Jeko Anita, Bunting Daniel E, Sette Alessandro, Kloetzel Peter M, Stumpf Michael P H, Heck Albert J R, Mishto Michele", "evidence": [ { "database": "IEDB", "id": "484416", "url": "https://www.iedb.org/epitope/484416" }, { "database": "IEDB", "id": "583292", "url": "https://www.iedb.org/epitope/583292" }, { "database": "IEDB", "id": "584495", "url": "https://www.iedb.org/epitope/584495" }, { "database": "IEDB", "id": "589353", 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Ramos-Fern\u00e1ndez Antonio, Lombard\u00eda Manuel, Jeko Anita, Pazos Florencio, Paradela Alberto, Santiago C\u00e9sar, Heck Albert J R, Marcilla Miguel", "evidence": [ { "database": "IEDB", "id": "584495", "url": "https://www.iedb.org/epitope/584495" }, { "database": "IEDB", "id": "608832", "url": "https://www.iedb.org/epitope/608832" }, { "database": "IEDB", "id": "612274", "url": "https://www.iedb.org/epitope/612274" }, { "database": "IEDB", "id": "612867", "url": "https://www.iedb.org/epitope/612867" } ], "reference": [ { "type": "PubMed", "id": "27920218", "url": "https://glygen.org/publication/PubMed/27920218" } ] }, { "title": "Separate effects of the ankylosing spondylitis associated ERAP1 and ERAP2 aminopeptidases determine the influence of their combined phenotype on the HLA-B*27 peptidome.", "journal": "Journal of autoimmunity", "date": "2017-05", "authors": "Mart\u00edn-Esteban Adrian, Sanz-Bravo Alejandro, Guasp Pablo, Barnea Eilon, Admon Arie, L\u00f3pez de Castro 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"title": "The Intergenic Recombinant HLA-B *46:01 Has a Distinctive Peptidome that Includes KIR2DL3 Ligands.", "journal": "Cell reports", "date": "2017", "authors": "Hilton HG, McMurtrey CP, Han AS, Djaoud Z, Guethlein LA, Blokhuis JH, Pugh JL, Goyos A, Horowitz A, Buchli R, Jackson KW, Bardet W, Bushnell DA, Robinson PJ, Mendoza JL, Birnbaum ME, Nielsen M, Garcia KC, Hildebrand WH, Parham P", "evidence": [ { "database": "IEDB", "id": "645456", "url": "https://www.iedb.org/epitope/645456" }, { "database": "IEDB", "id": "646060", "url": "https://www.iedb.org/epitope/646060" }, { "database": "IEDB", "id": "649089", "url": "https://www.iedb.org/epitope/649089" } ], "reference": [ { "type": "PubMed", "id": "28514659", "url": "https://glygen.org/publication/PubMed/28514659" } ] }, { "title": "Outer nuclear membrane protein Kuduk modulates the LINC complex and nuclear envelope architecture.", "journal": "J. 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"authors": "Wu Ci, Shi Song, Hou Chunyan, Luo Yang, Byers Stephen, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8NF91", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8NF91" }, { "database": "O-GlcNAc Atlas", "id": "Q8NF91", "url": "https://oglcnac.org/atlas/detail/Q8NF91" } ], "reference": [ { "type": "PubMed", "id": "36240223", "url": "https://glygen.org/publication/PubMed/36240223" } ] }, { "title": "Immunopeptidomics-based design of mRNA vaccine formulations against Listeria monocytogenes.", "journal": "Nature communications", "date": "2022-10-14", "authors": "Mayer Rupert L, Verbeke Rein, Asselman Caroline, Aernout Ilke, Gul Adillah, Eggermont Denzel, Boucher Katie, Thery Fabien, Maia Teresa M, Demol Hans, Gabriels Ralf, Martens Lennart, B\u00e9cavin Christophe, De Smedt Stefaan C, Vandekerckhove Bart, Lentacker Ine, Impens Francis", "evidence": [ { "database": "IEDB", "id": "615585", "url": "https://www.iedb.org/epitope/615585" }, { "database": "IEDB", "id": "941931", "url": "https://www.iedb.org/epitope/941931" }, { "database": "IEDB", "id": "2065391", "url": "https://www.iedb.org/epitope/2065391" }, { "database": "IEDB", "id": "2245900", "url": "https://www.iedb.org/epitope/2245900" }, { "database": "IEDB", "id": "2247819", "url": "https://www.iedb.org/epitope/2247819" } ], "reference": [ { "type": "PubMed", "id": "36241641", "url": "https://glygen.org/publication/PubMed/36241641" } ] }, { "title": "Direct identification of HLA class I and class II-restricted T cell epitopes in pancreatic cancer tissues by mass spectrometry.", "journal": "Journal of hematology & oncology", "date": "2022-10-25", "authors": "Fujiwara Kenji, Shao Yingkuan, Niu Nan, Zhang Tengyi, Herbst Brian, Henderson Mackenzie, Muth Stephen, Zhang Pingbo, Zheng Lei", "evidence": [ { "database": "IEDB", "id": "444264", "url": "https://www.iedb.org/epitope/444264" }, { "database": "IEDB", "id": "449014", "url": "https://www.iedb.org/epitope/449014" }, { "database": "IEDB", "id": "484416", "url": "https://www.iedb.org/epitope/484416" }, { "database": "IEDB", "id": "545558", "url": "https://www.iedb.org/epitope/545558" }, { "database": "IEDB", "id": "986529", "url": "https://www.iedb.org/epitope/986529" }, { "database": "IEDB", "id": "2229166", "url": "https://www.iedb.org/epitope/2229166" } ], "reference": [ { "type": "PubMed", "id": "36284347", "url": "https://glygen.org/publication/PubMed/36284347" } ] }, { "title": "`Two Birds One Stone` Strategy for the Site-Specific Analysis of Core Fucosylation and O-GlcNAcylation.", "journal": "Journal of the American Chemical Society", "date": "2023-07-26", "authors": "Luo Yawen, Wang Yuqiu, Tian Yinping, Zhou Hu, Wen Liuqing", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8NF91", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8NF91" } ], "reference": [ { "type": "PubMed", "id": "37340703", "url": "https://glygen.org/publication/PubMed/37340703" } ] }, { "title": "O-GlcNAcylation of Raptor transduces glucose signals to mTORC1.", "journal": "Molecular cell", "date": "2023-08-17", "authors": "Xu Chenchen, Pan Xiaoqing, Wang Dong, Guan Yuanyuan, Yang Wenyu, Chen Xing, Liu Ying", "evidence": [ { "database": "O-GlcNAc Atlas", "id": "Q8NF91", "url": "https://oglcnac.org/atlas/detail/Q8NF91" } ], "reference": [ { "type": "PubMed", "id": "37541260", "url": "https://glygen.org/publication/PubMed/37541260" } ] }, { "title": "Targeting of intracellular oncoproteins with peptide-centric CARs.", "journal": "Nature", "date": "2023-11", "authors": "Yarmarkovich Mark, Marshall Quinlen F, Warrington John M, Premaratne Rasika, Farrel Alvin, Groff David, Li Wei, di Marco Moreno, Runbeck Erin, Truong Hau, Toor Jugmohit S, Tripathi Sarvind, Nguyen Son, Shen Helena, Noel Tiffany, Church Nicole L, Weiner Amber, Kendsersky Nathan, Martinez Dan, Weisberg Rebecca, Christie Molly, Eisenlohr Laurence, Bosse Kristopher R, Dimitrov Dimiter S, Stevanovic Stefan, Sgourakis Nikolaos G, Kiefel Ben R, Maris John M", "evidence": [ { "database": "IEDB", "id": "191554", "url": "https://www.iedb.org/epitope/191554" }, { "database": "IEDB", "id": "193793", "url": "https://www.iedb.org/epitope/193793" }, { "database": "IEDB", "id": "449014", "url": "https://www.iedb.org/epitope/449014" }, { "database": "IEDB", "id": "459144", "url": "https://www.iedb.org/epitope/459144" }, { "database": "IEDB", "id": "545558", "url": "https://www.iedb.org/epitope/545558" }, { "database": "IEDB", "id": "734405", "url": "https://www.iedb.org/epitope/734405" }, { "database": "IEDB", "id": "770216", "url": "https://www.iedb.org/epitope/770216" } ], "reference": [ { "type": "PubMed", "id": "37938771", "url": "https://glygen.org/publication/PubMed/37938771" } ] }, { "title": "Exome sequencing implicates ancestry-related Mendelian variation at SYNE1 in childhood-onset essential hypertension.", "journal": "JCI insight", "date": "2024-05-08", "authors": "Copeland Ian, Wonkam-Tingang Edmond, Gupta-Malhotra Monesha, Hashmi S Shahrukh, Han Yixing, Jajoo Aarti, Hall Nancy J, Hernandez Paula P, Lie Natasha, Liu Dan, Xu Jun, Rosenfeld Jill, Haldipur Aparna, Desire Zelene, Coban-Akdemir Zeynep H, Scott Daryl A, Li Qing, Chao Hsiao-Tuan, Zaske Ana M, Lupski James R, Milewicz Dianna M, Shete Sanjay, Posey Jennifer E, Hanchard Neil A", "evidence": [ { "database": "RefSeq", "id": "NP_892006", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_892006" } ], "reference": [ { "type": "PubMed", "id": "38716726", "url": "https://glygen.org/publication/PubMed/38716726" } ] }, { "title": "[Rare forms of autosomal recessive spinocerebellar ataxia associated with mutations in the ANO10 (ATX-ANO10) and SYNE1 (ATX-SYNE1) genes].", "journal": "Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova", "date": "2024", "authors": "Nuzhnyi E P, Protopopova A O, Abramycheva N Yu, Protsenko A R, Illarioshkin S N", "evidence": [ { "database": "RefSeq", "id": "NP_892006", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_892006" } ], "reference": [ { "type": "PubMed", "id": "39269294", "url": "https://glygen.org/publication/PubMed/39269294" } ] }, { "title": "Systematic Evaluation of Affinity Enrichment Methods for O-GlcNAc Proteomics.", "journal": "Journal of proteome research", "date": "2024-10-04", "authors": "Hou Chunyan, Wu Ci, Wu Zichun, Cheng Yifan, Li Weiyu, Sun Hui, Ma Junfeng", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q8NF91", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q8NF91" } ], "reference": [ { "type": "PubMed", "id": "39302247", "url": "https://glygen.org/publication/PubMed/39302247" } ] }, { "title": "Centromere and telomere movements during early meiotic prophase of mouse and man are associated with the onset of chromosome pairing.", "journal": "The Journal of cell biology", "date": "1996", "authors": "Scherthan H, Weich S, Schwegler H, Heyting C, Harle M, Cremer T", "evidence": [ { "database": "Reactome", "id": "R-HSA-1221632", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1221632" } ], "reference": [ { "type": "PubMed", "id": "8794855", "url": "https://glygen.org/publication/PubMed/8794855" } ] }, { "title": "Association of BRCA1 with Rad51 in mitotic and meiotic cells.", "journal": "Cell", "date": "1997", "authors": "Scully R, Chen J, Plug A, Xiao Y, Weaver D, Feunteun J, Ashley T, Livingston DM", "evidence": [ { "database": "Reactome", "id": "R-HSA-1221632", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1221632" } ], "reference": [ { "type": "PubMed", "id": "9008167", "url": "https://glygen.org/publication/PubMed/9008167" } ] }, { "title": "Protein-protein interactions in the synaptonemal complex.", "journal": "Molecular biology of the cell", "date": "1997", "authors": "Tarsounas M, Pearlman RE, Gasser PJ, Park MS, Moens PB", "evidence": [ { "database": "Reactome", "id": "R-HSA-1221632", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1221632" } ], "reference": [ { "type": "PubMed", "id": "9285814", "url": "https://glygen.org/publication/PubMed/9285814" } ] } ], "pathway": [ { "id": "hsa:23345", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?hsa:23345", "resource": "KEGG Pathway" }, { "id": "R-HSA-1221632", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-HSA-1221632", "resource": "Reactome", "description": "Meiotic synapsis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M6Z1N5-1", "protein_name": "Nesprin-1", "gene_name": "syne1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASLSPFGRSSKDIMNLMQKLQDEQESVQKRTFTKWINSHLAKHKPPFEVNDLFEDIKDGVKLLALLEVLSGQRLPCEQGRQLKRIHWVSNIGTALKFLEGRKIKLVNINATDIADGRPSIVLGLMWTIILYFQIEELTSNLPALQALSSSASSVDSMASSETGSPPMKRKVVTKFQGNAKRALLRWVQNTATKRLGIEVKDFGASWRSGVAFHSVIHAIRPELVDMDVVRKRSNRENLEEAFSVAENELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHYPDPHQSETDGQQEELVRSIPTFALSIPALQYDPQDIELMLEREERKVLREVKIWLDQLERDVLRAQGSEESLTDKYQAFKSFRVQYEMRKKQIESLLQPVHRDGKLSVDQAVVKQSWDHVSVRLLDWHIHLDKSLPGPLGVIGAWLHRAELSLREDVPIQQAHEETANIIHRKLEQHKEVLKNLEGHRQTFQQIHRDRSVNGVPVPPEQLQDMAERFNFVTTSSHVHLIKFEFWEMKYRLMAFLMLAESKLKSWIIKYGRRDSVELLLQNYIVFIEGHKFFEQYETTFRTLKQAADTYLKSGTSDGKITKRAEEVEGVNKFLSDATAQWKNLSVEVRSVRSMLEEVICNWEKYSSTVASLQAWLEDAEKMLNQSESDKREFFRNLPHWIQQHMDMNDAGNFLIETCDETVSRELKQQLLLLNGRWRELFVKVKHYARADEVDKLRKDYDDGIEALKAFIDTANERMNTPVQVSFLNIRTYLQDVEDIKHKVPSMEAAYKTATRNAQQLTKDLSEDEIAHMLNNMTNIKDELSKIRERALPLLRDSQAMLPPLEEMEKNITGFYQSLEKASRITSSRDSEAPGDFTQKCQELVTYQQSCKKCLSVIDKNHQVILKSLDTSKNLKHLDTSLLERRITELQASSQGMVKETTEWKQHVEANSSLMKRFEESRVELEKVLKIARSSMTERGNPEDLLKKHTEFFGQLDQRVLNAFLKACDELTDILPEQEQQNLQETVRKLHKQWKDVQTEFPYHLLHLKVDLEKSRLMTSLQECQAELARENRSLPSVGSERLIKEHRMFFKEKGPQALCEKRLQHMDELCLKLPESQQAQQTLVIARTAFAEVKEEIDSTHQRLMQHPDKWKEFNTRFSELSAWVTSKESQLRLLRNRAGDPSKFGQVKSTIESLRNDAELQEGNVSWLKNRLAALIEICTESDAQRQGAALSKLSNDFKGLLISLSESEKVVLAVSDCVQFREEVKTTLEELTQGQKELQSDNSKILDSESVREAQQLLLLHQQQLKRLRLKRKDMQEQINRGKQLQIEEGLEESLQDDLQKLESTLKKMDENTESQEKNLEVTLSAWQEFDAQQASVREFVGKVRSVTEREMNFSSPESLSSELEQTKDLLKQCETEVRQVNTLLKRATEIQLGPKNQSLLQDQARALSEQVDKVEKGLKRDVKTLEGMKSQWDLFGSEFEAFSSWIMEREREMDALKSSSIPLDQQICTVQTIRDGLQERSEVLSNLEEKSQSLVQFVSSGESARIKARLTQIGRYWEELKESVDHLSGQLEESSSHQTKFNSNLQQVQSEVEEIQKKLDNPVTSCISSSETYKTLQSHMDVFQSLEKLKATLLSLSAGARRLSEREKAERAVAALQQNYEQCLKQAKEKQNQTESLLSHWQKYEKDWSALKSCLERCEAACGPDSQSLPVDKLKLDGELLELKHLQTELESLEVVYNRLGAQTPSLYTTASDERVKTLKEDHQQLEKRWMCQTTAIPHRIQVLQQHLSQVDQFDQALQKFFKWGESFLSSLHSSSHTDITDLQPSTNDIKEKREALLKQSIVRQNLQQQTKTLCDVCEPAEVQHLQGRWESSLQPYLEAHQLVELRGESLEKLEAFLHTHSVAAGVLQGLRQTVESAGSWDKSRVEELQRELEAIVPDISRLETLAVNLDGNLCKSHLHLMSGKETRSSCRSLADSLSAELDAVRNLLGSKQSEAEALGALWSSFRQRKEQLLKTVEDIEEKADQQGLKEPNVLTLQQRLRFFNQLEDELQSHQHEEQWLRDKGQQLAHRDAELGSEVLREINLLQTTWEDTKKLITERQEQSSALVDLMKDYQTLKSSINSILESADAIADIKSVLKDQEDTRRSLLKHEAVKADMASHQDVLDRFSSKGKKLLSELNKIPDCDTQIVKTEIDATVDQWLDVSEKIEDNLESLKRSSALWVEIYDINGEIESWSNSSVMDLTDGLNNFNDSQKTAHKLSEVKVDVGLKEKKIDALQEKVSEMKQLCGGQDVPAKLQVMETDLRRKLNSIEELCDQAKNNLQDFCCQKKQLEDFLSQMSEWLMSVERSLVDSPCGTAPEEICRVKEIQKELQNQQASIDSARESLNTLCRKYPSEELAGLGSSLTDLIKKYETVNQICVKRLGSMQHGLQQHFNDLVKEFHTWLSGQKDIVRECADHSGDMSVVERKLQKLKGALERVEDGDDRLTLVCTEGEKLLLHLPKASAGQVQQSLSSIQQDWDSYVEQCRQNQQNLEDSASLLSGFDGRLQRLSRWLERMDVKMSTELPEGRHGDQERVTLERVEEFQHEVLKERDSFEGLCQEAQALSEGGHGSGSEVRASAQLQHQHQSLLKAARERLRVCQLSMQEQQNFQETLQSTWLWLSSAQERLTALNSTGGNKETLEKRLALVQDILLMKGEGEVKLNMTVGKGEQVLKNCSRDKQEVIRSQLKSLKDSWANILMTAMSCHSRLEWTVAQWSSFQESKAQLQQWLEMVEQEAGVALPQQPGLKEKAALLERLRVIQADVEVHSTALSRLNEKATELYEKTGDQAFAERPKSDFNTQFTNITAVIKSKVQQMEEIVKEHEQYMESVRDLNDWLTSAKEELQRWSDMSGDAASVQRKLSKVRGLLDSRKQGRERLTRVQSCGAATRDHTSTVGCEVLEREEAGLLSAWEQWERGAKHVCSGLEGVLAQMANSEQEFNSLAAQLEQDLQEFSSKLQEWRIKLQQVEEMSAGEEAVQGWQIAKDTLEALQNVEPMSDNLKCQLNDLCRFSRDLGAQSERVSALIKEYNSLSLQASRECQGKEKLLEQRFRAAFRDFQQWLVNAKINTAKCFDVPQNLAEASSSLQKIQEFLSDREQGQGKLNTVAASGELLMSIAAKDRVESVRAKINSAREDWKTLMTNLHQRENALQNLQAQMRDFETSVEPLQDWLNDTEEAVQESSSRLQDLTAKKQELHRLQSLLEELASKEPQLLRLREKAQQLWDGHTAGKGFVHRVSQLSAQYLALSNLTKEKASRIERVVSEHQLFSQGLKELQNWVSDTSHMLQTYCTPTADKNVLDSRMIKLEALLTARQEKEIQLKMLLTRGESVQRNTSADGVPLVRQQIEDLKDSWDGLLSASIQCKSQLEGALSQWTSYQEDVRQFVSWMETVEETLSSADKQCSEMRDKTTNLGKAKLLLEDVLSHNSVLDVISMKGSNMAEHYVTQLEIQDLQERYNIVKDKAQCAVAKAEELVSAHQEYQHSLHEFKDWLDQQQERLSCYTQLEGDTETLEDTLRKLQELQVHCTEGQALLNTLLVSREQVIPWGVPQLEDRCLEGVQQEWSSYQSRLTDTRSQLNSALAKLRQIEQKFQRLDNWLKGMESKGQLRTGRRSDRATKEAQLQLLKGWHEEVLVYQEEIEGLSVLAQQVLEETPISSRVSTRATQLTSRYHALLLHLLDTIKQLKEEVSCIEESQSVFCTFSDWLSTAQKNFSSVTTTNIDVVDRAAMEKKMKKLEALQGDMELGHTFLKTMREKTDRAMMFLEEPEAEQLKEEVDSRLSQLETLIRALRSEISATEKSIQLSKDFLDKYKTQTQWLSETKSLLASPVEPKAELYQKKAQLAKYKTIQQTIQSHESAVKSVIEKGDALLETIRDPSISENIGKLKTDYQDLCADAKVHVQSLTESVREHEDYNSELQEVEKWLLQMSGRLVTSDSMQSGNLEMATQQLARHKAIMEEIAGFEERLSSLKDKGDHLVSSCTEQVQAKISQQIQAHQQGTRDSYSAICSTAQRVYQSLDRELQKHVSHQDTLQQCQTWLSSVKEEIQMQPQTPYGLQEALKQVKHFRALQEQASTYLDLVCSVCDLSDESVRATAAKIQQTKTMIEERMSTSQELSDSWREIKEQKQELSTLFQDMEQQLQSLSRRPAELETKIAQNMLDQAREFGQQLQNRQSTLTKMTELVSKLTEGKESPEHTEIGRLSHAWLELCHQANKLQTQREEDLQRTKEYHDCISAMEALFEQVSKEWDNLARTDAESSSDHLEALRKLSVVLKDKKSTLEDLKEQKQKVMYHLNLDDKELVKEQIGHFEQRWAHLESLIERKIQDSILTLEDMGQVEACLREAREWAEEQQPTLSEAMKMSPPPELAQSFLFDHLSICSELEAKQLLLAQAMGDADRVLAHLGLNERQRLQQLISETQAEVECLSVKVAQRRKHLSKAFTERTQFLLAVNQAITWVQQNEKKAQAEEYIALLPDDLSKQVRTCRNIQSSLRAYQSELTSLWSQGRDLMKDASEEEKTEMLHKLQELQSIFEVALQKCSQRLQDLEKVLVTRKYFKADLEKICQWLKQADIVTFPEINLMNGDAELCSQLTKYQQILDQAMEFENLLLTVQRTGQEILPTLNEVDHCYLDEKLIALPQQYNNILGLAKEKQEKIQQAILARQEYASFIDVTHKALKELEEQFHSLGTQPIGLKTEEVVSLQADYKALLEELTNLGQAVGELNQKKEGFRSTGQPWMPEEMTQLVSLYNGLKRLIEQRVEHLDDTLESFEDHQAMAMQVDSELKATKEQLVKVNAETQSAEERLKNYHALAASLQGASSHLTRLMEQMDNLVSHMDTAAHEVSKQRVTSWQEELRSLQSSVGELIVECENRFVQSKDFETEVNRTLTWLQQIKDELGSEVVVDVKVEKVQEEIRKQQIMQEEVQSRLRIVAALSTREKQKYTSANELVPAHVDSSLQEMAKLEADVQRALSSKQITLEQALVLCQKYHSRMQAACEWLEDAVGFLQQASLGVDVENYEECLRQQEDIMATEQEFLGVLEELESLPPQLENLVNPTAKEQLRLSVESAQQRGVEVRDQLQCHQDVLNSCVAQWNSYQEARQTVIDLMNEVEKKLTEFSTAKAATNQEAEEKLRSHKSLVSMVNSFQEKLTGLEEQASQLEQIGSDASKATISRSMTTVWQRWTRLRSVARGQERVLEDTAHEWRTFREKMMKVRSLTEEVKGRVPDCTAEKASKATLQSHLDQYELVSQDLERELSSLTLLRQYALSLLHDVEVSVPTADHEQLPSLKEIKAVQDQLESLLQKARAGKSRVQQELSDREGVERGLSLVKSWIQDSRELLLNPTSDLDILSQELEVMHGELITHRQNVDKLAEQQQSKYLDLYTILPSEISMQLAEVSLALGSIEDQVQARERDIQKSRVIKEEFNSRIHDVSEKMKAVSTALKEKATDIDQAKDEARRLCDELDCCGRTLAELEAAVQDFGRRNPLIARQLADAIAKLREIHHHTLRLADYKTIWLKKADAHLDEYNEMFEFIVKWTDRARSLVKANIIWNSSSHLQEQIRMYQAVLRESRELHGDLDSMQEKVEILSETLQVEAMGQQVSELSRHTEELEQSIRSRLQSLQDAAKDMEKFESEVKVLHVSLDQVQATLTSPELARLSLKEQLAQRQRLLADMESFKQQVEAVQECQSALRVPEEVVTSLSICRTALNLQQEASQLQHTAIQQCNILQEAVVQYEQYEQEVKNLQVMIEDAHRVIQDQPVNTSNIQELQAQINHHEELAQKIKGYQEQIASLNSKCKMLTVKAKHATTLLTVSEAEGLTESLEELDGELIKRKSQAQVSMSAGRSQSLLSPVTEESGEEGASEICSPAFCPSPSSTNTEAVISKMSMGRSSLTRAPVQELYNPALESVASLDDLQRSWETLKNVISEKQKTLYEALEKQQRYQGSLQSISSKMESIETRLNEPPMHDLSPDRQMILHQNQMEEIIRLQDDIHELQSSFTEELYNPDSVDSDSADQLAMQSSLTVLAERMATIHMKASGKRQILEERQSERVEKQQQAQALQHYLNQADQLDQWLKSTHGYITSCSQDSDAEEQLTDCQNMLLEMEEKVLALSELSRHSESLLLEGRPENREDAEQLARKLRTLKGSLLELQRMLQDKQINLQATLIWEELKGPQRASDSLQEASDSSESDSTLSQSPNMQDWLAQARTTRSLQHQDTLQKQKELEEQLAEQKKLLKSVASRGEEILTQQASPVRASATETLSPDVELEGDSEAVKKQRRKRWESLKKDMTTKLQLLMNTLEQDSKQPFYSRTACVKTAAPVYKRETHVQDKSNLMSLHNGFSQTIQEMTPQATEREVILMEQQLYSAVTATSSWVDDVENTLFSGPALLTENADTQLSNHETLGKEVTEVTQEVGHTQGLIKGSVGLSEDEQSLMKDTLDCLTRRLGALDSALDRRCDSMRSRMRELSAFQTELQRLFTALSESKFQIIQKMAGVLDHTTTKQIETIAEAEETLKDFEHRITELKARGAELQPDQFSTNELLKLQDAYEELVMTVGSRRSGLNQNMALKNQYERVLQDLIDLVDTAQDKMTADQKMIAASVEDVHNLLDKHKEFFQGLEWHMVLTETFYKKSSAFVLPRERQTLEETLARAQDVLKQAHKKGVELECVSETWSRLVLDYQTLYRLLEVVEGSLPSVGLVEETEERLNERIQLYQALRSSLTEHQHKLHQVLEEGKHLLSYVSCSSLENQLTVLGEHWLNNTTKVNKELQNLQSMLKHLTRYKSESGELSRWLLEALERLEFWNTQFVAGPQELETVKGQLSAFLEFSKEVEARSNLKASVLNEGNQLLRLKKMDTASLRAELACLDSQWSELLSRIPIVQEKLHQSQMDKLASRHAITELVNWISLMERVIEEDEENLKGAVGSKVIQEYLQRYKGFRVDVNCKQLTVDFVNQSVLQISGADVESKRSDKTDFAEKLGAMNCHWQILQTRITERVQYLEGLLTSWVEYEGKVQGLQAWLDAQEERLKRKHRIENLSSVQNALKDCQEMEVMVKEKERELERVEEQACALVQNKTDEACAVVMESLRALNNTWANLDHLIGQLKISLKSVQDKWNQYKQASEEINGYLTEGRYSVSRYRLLTGSLEASRLQVESLQNLQEELEKQESSMRKFGSVTLQLLEECHPSVSDTLNNTLKDINARWSSLQEEIVERLKSSKALLQLWQSYKDLYGQSDSSVQTLEEKANQMLKTASHKDITEEEVSAWIQDCAELLRSQAPVQASLQVLMELGEQLKQQVDTSAVASIQSDHLSLTQRLSVVEQSLSRQQVALQAGVRDYETFNEQLDSLSRWIVEAEEVLKGQDPNGSSDQSLIQDRMEDLKKQMLKFSSMAPDLERLNELGYRLPLNDSEIKRMQNLNRSWSTTSAQTTERFCKLQALLLQQQTFLEKCETWMEFLVQTEEKLAVEISGNFQSLMEQQRAHELFQAEMFSRQQILHSIISDGQHMLEQGQVDDRDEFKLKLALLSNQWQGVVRRAQQRRGIIDSLLRQWQRYREMVEKLRKWLLEVNHQTQSLQAGTPVPLQQARAMLDAVQLREKVLLRQQGSYILTVEAGRQLLLSADSRAEAVLQEELLNIQERWRNANIRLDEQKKELAVLLRDWERCEKGIGGSLEKLRAFKRQLSQPLPDRHEELQAEQMRCKDLDSMFDGWKEDLTHLTVLRESLSSYISLDDLRVLQERIELLHRQWEEICHQLSLRRQQVSEKMNEWAIFNNKYKELCEWLTQMESKVSHNGDVSIEEMIEKLRKDYQEEVSAAQENKLELQHLGERLARASHETKASDIEHKLSKVNERWQHLLDLIGARVKKLRETLVAVQQLDKNMNSLRSWLAHIETELSRPIVYDTCDYQEIQRKLDLQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRSLDRRWRSICAMSMERRIRIEETWRLWQKFLDDYSHFEEWLMLSEKTAALPNSSGVLYTIAKEELKKFETFQRHVHESLTQLELINKQYQRLARENRTDAACSLREMAHNANQRWDNLQRRVSSVLRRLKHFISQREEFETARDCILVWLTEMDLQLTNIEHFSECDVQAKIKQLRAFQQEITLNTGKIDHIFLQGEALLEKSEPIDAAVIEEELEELQRYCQEVFGRVERYYKKLIRLPLTDDEHDVSFSDREFDLDEAADVSSFPWSERLGDGFLSPLPSSSRSAPLRAERSGRDTPASVDSIPLEWDHDYDLSRGLESASRALSSSETGDQAEDDGYLQGSASALSDVVIPESPEAFLKLTEQTLRSSAGDAGSLETHIRQLDKALNTSCFHLQQTENIIRSRTPTGPELDATYMGYMRLLEECRGSIDAVKRVGFELKDEDDKISGFVNPNSSESQTSGVIERWELLQAQALSKEMRMKQNMQQWQQFNSDLSSICSWLDQTEEELQQERGLDLGTDIQTIELRIKKLKELQKALDKRKAIVLSINLCSAEFVQSDSEEARELQRRLKEMNNRWEKLSSSLDEWRTALQHALMQCQDFHEMSHGLLLWLENIDRRRNEIVPIDHTQDSDTLQEHHKTLLQIRRELLDTQVKVASLQDMSLQLLVHSEGSDCLEAKEKVHVIGNRLKLLLKGVTRDIRELQKTLDISSSQQDLSSWSSADDLDTSGSLSPVSGRSTPSRQRPPRGKSSVSEPGACVSSLLHSRSLNAAGSAFSHSEDEERPSWCRSFLKRVFWAALPLQIILLLVLIVACLVPTSEDGYSCAQLNNFARSFHPMLSYTNGPPPI", "length": 8827 }, "evidence": [ { "id": "RGD:620546", "url": "https://alliancegenome.org/gene/RGD:620546#orthology", "database": "AGR" }, { "id": "HGNC:17089", "url": "https://alliancegenome.org/gene/HGNC:17089#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-071218-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-071218-4#orthology", "database": "AGR" }, { "id": "MGI:1927152", "url": "https://alliancegenome.org/gene/MGI:1927152#orthology", "database": "AGR" }, { "id": "FB:FBgn0261836", "url": "https://alliancegenome.org/gene/FB:FBgn0261836#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PC75-1", "protein_name": "Nesprin-1 isoform X1", "gene_name": "syne1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEVKGKVARRWEDVAAKKKSGNSLNLVQGVSQHLRDEQEAVQKRTFTKWINSHLAKRNPPLVVSDLFEDVKDGVMLLALLEVLSGHKLPCEQGRKLRRIHWVANVGRALKFLEGRRSAYRGSPIKLVNINTTDVVDGRPSIVLGLIWTIILYFQIEELTSHLPALQPQSSSNSSVESSNSTETSSPPVKRKPRLSFQGGAKRALLKWVQNTATKRMGLDVKDFGPSWRTGVAFHAVIFALRPHLVNMERVWRRGNRENLEEAFSLAERELGIPRLLDPEDVDVDKPDEKSIMTYVAQFLKHHPDRQHTETGQQQEEFYLAPRAIEEMLEKEQRKTLRELKAWADQMERDCAQAQRDGGSLTVRYQTFKRFRVQFEVQRRQVETCVQSTQKDGKLTADQALVKQAWERLCKRLLDWHLQLDSGLPHPLGEVGVWLHQAEEILREELIPQQAHDETAKAIHKKRLRDQEILRLLERHKQTLQLIHRDRCVNNMPIPTEQLQDMAERLHYISTSSHIHLSKLEFWESKYSMLAFLTLAESKLKSWIIKYGRLESMELLLQSYGTFVEGQQFFEKYESSHQSLLQAAELYIKADSSVEGVVKLFLREVCDQWRSLSVEVRSVRSMLEEVQCNWLRYNSCVASLQAWLEDAQGALRQPENTKREFFRNLPHWMDQHAAMNDAGNFLIETCDETVTRDVKHQLLLLNGRWRELFLKVKQYARLPETHNVRIHQDIQEFLDASINKLTSPLQVSLLDVKAFMQDVEEIKHKLPAVEAQYKAAARSAQLLAKVHGGGNKARSTIPTTEAHLHQLKEKCPLTLKECQALFPLLEELEKQISAFYQTAEDAGHIITQQHNQEMCQELQTQQQTCKRCVCAIERSYLALQRALCCAKSLHNFDTSLLQNRVTEIQTTAQALMQEALEWRQVAETNGSLMRRFEESRADLEKALRVGQACLKERGDPDELFRKHNEFFGRLDQHILSAYLKACDDLTDIISEEDQKSLRDTVRRLHKQWKDIQAEAPAHLLRLRVETERRFVMATLQDCRVELKREDKALPAAGSEKIIKEHRAYFRQKTPLSACEKRLKTMKHFCQELPENDRGYQMLEGAKDHLLEVKGLVDQTHLRLQQHPDKWREWHVRFSKLSEWLISTQNGAENSSVQMQRRAIKAQSETLDWLKARLAVLEEISPESEAHMQRDALEKLSQQFFAALLSLSEAAGVANEASVKTEEELKEEVNDDDLIQIQEHRQILNAESATEAKQLLLIHQQNLKTQQGKDMDVRCQGNFFKEDRAAQEKHLQVTVSSWQEFEAEREAIWQFICHVSPVLQRELIFSSLDNLKSERNNIQELHEQGYMFAVRAESLVKKAADIKLGPQNQSMLQDQAQSTKERLQEIQDSLRKIVTDLEMTHRWWQSFNRESEAFFSWVCDSKSDLEASAQTSATLDEQIHSVQMLKEGLEEKMDIFSQLETEFKTFINFITPNETGRIQARLMQIGRYQEEFKNNMDQRETELQSSLKHTKQFAQDLAEVESLLKGLLEKLNVSITSCTSASTTYKTLHEHMDAAQRLQQLGPRLMSLSLGWRRLPDAGQLEETVAELQKSHKLHTQQATEKQSKLENLLTLWQRYERDLSLLQSWSNRCESLCNSDSPYLTTDHVKLHSQLEMLQDMQSEVPSQESLLESLETRAESLYSSATEERTAELRDLHCNLEERWCSLSTNIPLRIQELQSHLAQLEQFSEVSLALTQWSENFLRHIQTTCKVSISDLQSADSKTKEDKTSLQTQGRSLEALQPHLDALSPSLAPKDLQHLQTRKEDCIQLFNEAQSLVEHRDQALLKLKDFYESYNKAKDSLQTIQQAVQERGSWDDSKVRDINQELAELAEELASLEVQAISLDIILNKAHFHLQGSEEERVSCRGLVDDVAMSVQVLQRSIGTKQSEAEALASMWSSFRGRKELLIESLAKLEDRANISWPTETNSQAFQQRLWLLKQLEEELEALQHSQLWLRERGTQLALRDPELAEEAQRDVTLVQSAWERIRRIVAEDHDLCANLLELCRDYQTLKTRIISVVERAHAITVSQSDPHNPDDIQRALSRLEAVRPELAATKEDLNKLIGSGRCLTDVLKKLPEESIQSENVSAEMDAIVDQWLDISEKMDADINLYTHSLELWNDINKMANEIECWTAVSVSELSEGSVGLLSSLDMQERLSDFKLELDNKEDELKILQAKMTELQELLKTQHTHTELQVMATDLRKQISHAAEVYEQTRGMCEDFSSQRQQLQDLISQISEQLKTSEDSLAEFSTSSDPENFAKIKEVERSQKQLEVSLDLAGESLRALCRTYPTQHLTLIGDAISNLVKRSEEVTQRRSQILGLLQEALLQRFNEKAHAFHGWLSELRAEAEVCFEQTGDAVAIFSKQEKLKTVLEEVAEGEKRLACVCVDGERLLLHLSKGGTGGVQEQLDSCQNALDMFVLECRQRLQSLEESAGLLNAYEARVVELSDWLQQLELRLKTDAPLWGESEPAAPDCSEELTRVEEIHRELLMRRASLERLCQSSVTVRERETRAENSAAEEMLLNHEALLQEARTRLRSLQDYQAFEEALRAVETWLKDVEIKLEKLESTEGNKKEVEEKLEQAQDILLMKGEGEVKLNMAAGKAELVIKTNGEVERGVICSKLQEAEDAWAALLLGAMSCHSRLEWTVSQWDLFVESRAQLQRWLEGVGLEVKGPLEPQLGLREKRKQLERLRLLSSDVEDHQGALCYLEESAAELYKRTGDPVFKEEEMVLLRAHFEDVKAAAEERVRLSEDVVHEHKTYMETTRELTDWLMVVGEELQQCSDPSGDSPTLSRKLTDVRELLERGACEGRERLRRVRLSAERAGRHTAAAGCELMDGEVAALARALHQWEGASLRARDALETAVAAATGAEREQTRLTAQLEGEMEKLEGQLKEWSDGLSCAERRNSGAAAVEGWTLAKGVLEGLQTAEVMEEKLKAQLNELCGFSSDLGPQSDRVSALIKLHNSLSLRASRECQNKEKLLEQRFRSSLHDFRQWLVNANISTAKCFDSPHSIQDASIALQRIQEFMSDKEQGQTRLSAVLTYGEQLSSVLAAERVEAIRTKANTAKDDWKSLMDSLQRRETALQVLQSQMQDFEASIEPLQDWLNRTEISVQESSARLHDLPAKRLELSKLQTLLEEMRSRESELAGLRGRAHGLWDGQGAGKSFVHRVCQLAACYLALSNLIKEKVSRVERVVGEHQLFSQGLQELQNWVSESQQVLKTCRCPTSDKTVLITRMGQLEALLAACQGKEIQLKMLITRGESVQRNTSAEGVPVVRKQIQDLKDSWESLLSTSIQCKSQLEGALSHWTSYQEDVSQFECWMERVEESLGNSDKHYAEMRDKTANLGRAKLLYEEVLSHSSPLETIATKGSNMTEHTATQQEIQKLSERYTTIKDKAKAAVSKAEELVLLHQEYQRGLHMFEDWLEQEQSNLAVLSPLDEDVNALEDTLKELQMLQSHCPKGHNLLSSVLSSRERVIPWGAPQIEDRALETAKTEWQGYQDRLAETKVQVEQALARVQQLEGLFQSLDQWLVDMELKVKVRSHRRSDVTAKETQLQHLKRWQTEAACRQAEVEGLSTLAQQVVEDAHVSGRISTRVTQLTARYHALLLQIQETLKQLQEEMQKITEAQNALRTFSDWLSTASKNFKIITERTEALDRITMEKKMKRLESLQGEMDQAHSLLKTLRESAELAVSFLDDPGASRLEREVQTGRSQLEELILGLREEHVTLERSIVLYKDFQERYKGQMQWLRETRALLSSTVEPKVELYQRKAQLAKYKAVEQTLLSRDSAVSFVVEKGETLLTLLHSPSITDNMSRLQADYQELRGTARTHVQRLEAQVKKQEAYHKDLQEIERWLLQMSSRMVTPEPSSSGGLEAATQQLARHKAIMEEIAGFEERLATLKEKGEELLSGCSERLQPRLRQQIQNHQQGAKDSYSAICSTAQRVYQSLDRELQKHVSVRDTLQQCQTWLSNVQEEVQLPEHAPQCLQEALTQMKQDRTLQEQASTYLQLVCSTCDLSDEKVQETAAEIQQVKLQIEERMLESQELTDNWREIKDLRSNLECHLLEAEQLLQNMLRRPAELEPKVAQNQLDQAQDFIQEMRARQVDLTHLRERINRLTAGQESPELMEVGRLRCSWLDLGRQAAQLLEQKEEDLQRSGDYHDCICMVEELFDQLSKKWDQLARGDIESTAECLDALKKLSTDLQDQRCVLDDLRNNRHGILPRLSLEDRDLVKEQVGYLEQRWTQVESLVQQKIQDSALTLEELSQIEDRLREAQEWAELQQPSLSEALKTSPPPDLAQSFLFDHLSFCAELEAKEKLLAEAMTDASSLSSRLGLNERRKLQTLVEEAQVEVASLGTKAAQYRKSLSKVFTERTQFLQALDRAAEWIKKQEQRALADDHVALLPNVLHKQVAACKNFTSSLRAYQVELTSLWVQGRDLVKDSTEEEKKETLHKLEELQVIFEASLQKSAEHLHHLEKALVIRKYFQMDLDRICEWLKQAEEATFPVIDLSGNDVNLQNQLAQYQQLLDHASEYENLLLIVQRAGQEILPTLNEVDHCYLDEKLNGLPQQYNDMLLLIREKRDWIQQVLLERREFESLIDITRKALKELQEKSDGLEMQSANQSLEEGERLHRSYEDLLKGLGNLFQGMKDLRCKTQDFLSMGQPYAHEVTGQLVYLHSSLNKQIECKIKVLRKTLKVLNDHRAAIEKMDCKITRLKEQLDRLESDIEADAMERLSTLYDLSKCLKEASTHSEGLKAQNDDLNQHFDLETLKTQVIFREEQLITLKQRINKHREKCERDLKGCKDFQIEGFFDWLKSLRDQLRRPLMFDEANVEIVQQEASSLSALQEEMKSRFRVLEDISNEEKQKYIHDQKSFPKLFETTLMDIPKLKEDLQQAFNTKQVALQSALSLFQRYHHSLQCIQQWFDDAGALLEQVLLEPDLEKISDHLKDLEDTTGREHAVRLMIDEMQDLIPQMGDHLSPTVIKHICQHCDESHHKATEVFEQLKQHQDNLQRSITQWRSFQDETDDVIRQMNDIEKRMKELTTAKANSEQEAEDNLHLYQRIMPQVQGLEDALNCLKEKAAQFDQPAIKDVTSQSVRSVSHRWSRMNSVARAQVKTLQDSAHNWRCIREKLEKMRAVCEDLHSRVPDSMVEKASSMAALHSLLEYHDSFSREVERESSALTLLRHHVLNLFLHPHTTAPTILNSEKPSLLEIQSIQDKYDILLQQVCASRQQVQMELLEREEVVRELGLLKGWIQDTQGLLLSPTADLDNLLTDLEAAHGGMLSHRQNLEQIVDRQQMKYQDLHTILPSEINTQLAEVTLALSSAEDQVQAREREVQHSRGIKEDFNSRLKDMSKKVKLISLKLKQKAVDVEEAKEETETLFEELEECARALSELDVAVQEFGEQNPLLAKQLSFSLSKLTELHAQTSRLAEERTTCLQKAERNFEEFNEMLTLTLNWTEKAETVVSTNLMWSPLSQMQEQIRTHQALLQEWQDLQGEFEGLVERVALLGEVVQTEMLHQQVSELSRHAEELQQGAKTRLLTLQDAAKDLTRLENDVKSLHQSIERVQETLASPDLARLSLREQLAQRQLLLSEMEGLKQQVQAMQMCQSALRLPEDVMAALPLCVTAQSLQHESSQLQHNTIQQCNILQEALVQYEQYEQEVKNLQRLIEEAHRVIQDRPVATGNIQELQTQIQHHEELALKIKGYQEQISALNSKCKMLTVKAKHATMLLTVSEVDGLSDGLEELEDEEDEMPKHPPTHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEVSSPPACRSPSPGPNADTSQGSGRAPLSRAPLQELYDPSMESAASANLDDLQRSWETLKNVISEKQKSLYEALERQQHYQETLQSVSTKMESIETALNEGLEPSKSPESQMAAHQALMDEILMLQDEISALQACFSQELQLDEDSLEADAGDQLALQSTLTVLGERMATIHMKASGKRQLLEERLNEQLEEQRQEQALQRYHSEAEELDNWLLSTRATLSSTLQPHPQDMDMEEQLIDCQNMLLEIEQKVLCLSELSVHSESLLLEGKAGTRGDAEQLSLKLHSLKSSLLELQRILQDKQTHIQGSLQEQEDTESDSSLSQSPNMMDWLSQARSTRNQQHQDTVQRQRELEEQLGEQKKLLQSVASRGEEILSQRTTPNGENCPAEFPNGEDGQWPACMSTKDQMRVRWENLSKDLKNKLQLSLNTMEQTPCNALYQPVSSPCGVFRGEQLSQDIPSPRSLFEGFNQDLEDLPQTGGTDSKRSRDLQKALYQAVSSASTWLDNAENELASGPVLLSDDSEAHLVHLEGLNKEVKNVNEEVCKCRDVLGGRERLWVEGRESDVVEEVFDGLEGRLKLLDTVLEQQCDGMKDKLQELTVFQTELRLLLTALNDSKYQLLQKMNAAMDRPASKQLEILAEAEDSLREFEQKVSEIRSRGETLQPNQICTQELLKLQDAYEELVEMVGSKRSGLNQSLVLKAQYERALQDLVDLVDTAQDKMAADQKMKVGSVIEVQILLDKHKEFFQGLETHVVLTQAFFRQISGLVVQREVQSLEETVAQAQAVLKQAHKRGVELEGILEWWSRLVGDYQALYRQLETVESSIPSVGLVEETEDRLSDRIALYQRLKASLSERQQQLYKLLEDGKRLVLHVSCSELESQLTQLGDHWLSTTTKINKELHRLDSTLKHWIRYQSESAELSQWLSSALDRLEFWSTQSVTVPQELETVRDHLHAFLEFSKEVDAKTSLRASVQSQGNQLLRLKKVDTAALRANLAKVDTQWADLLTRIPVVQEKLHQLQMEKLPSRHAITELMSWISLMENVIQEDQQKIMGAVGSVVVQMYLQKYKGFQIDLSCKQLTVDFVNQSVLQISNQDVEGKRSDKTDFAERLGAMNRRWQILQGLVTEKIQVLEGLLESWLEYENMVQTLKTWFSVQEEKVKKKHRIEDVSSAQNALKDCQEMEVLVKEKEKELEKAEEKGCLLIQDKKGEAGSFIMDTLKNLNQSWANLDHMIGQQTVSLRSVLEQWSLYKQAYEEIQGYLMEGRYTISCLHLLTGSPEAVQVQVENLQSLQDELEKQESSLRKLGSITQQLLKECHQSVSDSLNTALGDVNLRWNTLLEQISDQLRRSKSLLQLWQHYKALHAQCSADIHKLEEQVEHLLKSATHRDITQQEVKGLMATEGSVESVLQQLDEFSEQLRQQVDPSAMTTFHTEHLSLTQRLAAVGHALQRQQSLIEVSTRDYERFSKELNSLSRWAEEAEKVLKEQDPVGSPEISFVQDHMDKLKTQLLKLSSLSPDLERLNELGYQLPLNDNEIKRLQNLNRSWSSNSARTIERFSKLQALVLQRQTFLEKCDAWMSFLTQTEEKLAAEISGNYQSLLDQQREHELFQAEMFSRQQVLNSIVNDGHELLNQGQVKDRDDFGLKLALLSNQWQGVVRRAQQRRGIIDSLVRQWQRYTELIGKLRHWLHEVSLEPEDQQQGTTVALQQIRGMLDHIQLKERILQRQQGSYILTVEAGRQLLLWADARAEASLHTELTDVQERWRAINIRLDERKKELLSLLRDWDQCEKGITASHEKLRDFKQKLSVPLPDHHEELHTEQIRCKELEASIEGWADDVAGLCILRESLSSGLSADDLTVLHERLILLQRQWEETCHQLCLRRQQVSERLNEWAVFNEKNKELCEWLTHMESKVSQNGDVSIEEMIEKLTKDCQEEISVVEENKCQLEQMGERLAQASHESKAAEIQYKLCKVNERWQHLLDLIAARVKKLRETLVAVQQLDKNMSSLRSWLAHIETELSRPIVYETCDSHEIQRKLNQQQDLQRDIEKHSTGVASVLNLCEVLLHDCDACATETECESIQQATRGLDRRWRNICAIAMERRLKIEETWRLWQKFLDDYSRFEEWLKVSERTAALPNSSGVLYIVAKEELKKFEAFQRQVQEFLTQLELINKQYRRLARENRTDSSCHLRQMVHDGNRRWDILQRRVAAILRRLKHFIGQREEFETARDVILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFKQEISLNNTKVESVFGQGEVLMEKTEPLDAAVIEEELDELQRYCREVFGRVDRYYRKLTRLPLTDDECEGSDHEFESDDLSDLQWGEDGAIQQASSRPSSAANAPARTNGSGRDTPASVDSIPLEWDHDYDLEPMSHTMSAERVRQKDEDEDLLCMATAALTDVVIPESPEAYIKLTENTLRSSSGEAVRLLDTMLDSSRYSLQQTDGSMDAHDTSYMGYMRLMDDCRGSLNMVKRVEGELEEDEENLSGLSNPDNTETQSTGVIERWELIQAQSGDLEHRQTEDLLLWQQITSDLEDMEAWLEEAEAELAELRGRDLSADIHTIEQRIRRLKDLQKAMDSHKSKVLSINLNSVTLVQSDSDESKVLKAKLKEMNSRWDQLGKSLKDWRTALQDALMQCQEFHELSHGLLLWLENIDRRRNEIIPIASGLDRHTLRAHHRALKQIQRELTETEQKVDGLQELSGQLLVQAHGNECLEAQERVHVIANRLRLLLKAVETDLEMLEKELQDSGNRQDASLWSVTDETETSGSVSPVSEVSVSTKRQSLRGKCSVSDPGSSSRLRRHRLARGSGCDSSRSGSSGSQGGVAVVRCQPFLLRVLRAALPLQLLLLLIVGLTCLVPMTEQDYSCTLANNFARSFHPMLRYTNGPPPV", "length": 8731 }, "evidence": [ { "id": "HGNC:17089", "url": "https://alliancegenome.org/gene/HGNC:17089#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-4172", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-4172#orthology", "database": "AGR" }, { "id": "MGI:1927152", "url": "https://alliancegenome.org/gene/MGI:1927152#orthology", "database": "AGR" }, { "id": "FB:FBgn0261836", "url": "https://alliancegenome.org/gene/FB:FBgn0261836#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TCB4-1", "protein_name": "Nesprin-2a isoform X1", "gene_name": "syne2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASGEESSAPPEDERGVLLDIDDVHLLLQVEQEQIQKRTFTNWINAQLSKRSPPAAVQDLFSDLRDGTRLLDLLEVMSGQRMKRERGHGVFQQRGNIETALSFLKNKSVKLVNINIPDILEGKPSIILGLIWTIILHCHIKELASTLSFGSRSSSLDSLSSLDSFSGSPASSPVPRGASPLHTRFRLSAKKALLLWVRDQCQKVGCPASVRDFKSSWRSGEVFLAILCSLRPDLVDLSQFQTSSNQQNLEKAFYLAEKELGIPRLLEPEDVDVSNPDEKSIMTYIAQFLQYSNDLPLSDDDIELQTLLFPTCFSPVNLPTHFTPAVLASPLHQASPSQKAREMKCWLQRAYQELLDSWISTEGKGYAERYQAFQNFVGTYYEQRRPVIPVLSAMKRSTKPNEEQMELRKAWDAMEERLQEYKSELDVGLPAPLNTLGQWLQHIEAVLTEDSSNTEDHALAARDARHKQEQLKVLVEDLSQHLNTLHHYCNADDDNCPQVPVEKLEEIKRRFTSARVTAKYHGIKLQYREQMHHVYDLLGRLKSKLSLWKGPYGSQESVQSLLQDWHETVDKEGLVWKLKEALHKLKDTTISYASKAALADDLPVVNRQVKEADSETRAITDAAESVKSTMERVLGAWESYKDYLYRLQVWLGQESQTQMQEKEQKRFSSSENEWSTRQAQLNEAGNFLIEMSDTSTSHSLSDELRRLNMQWADFIKRTKFAVTHQPICTVPGVQTAQGLMQESGCVLRDTLEVSSGPLRIYRKKLQGIIKKISELDLNSIYPSPDCKEETLHKLKQALLEMYNTLNRVDQVCEGLQRAASLLEGRLAELENWSTEAQEVCQHLSSRQRRGHLEPHLRAKALISRGLQLEGQVVTEGEDLQVLVTSLQKNFTLPYLSITDLQDRLKQTVSLCQEVTEMLSCHGVKREGQPESARPASKVFVHTLSQPEFQTGSIQHYQMFSRSSKLSLDSPVESQKQDFHSFQLQTPFEATGGAKHQALSQFHDKSPEDQRKAKCQIQQADLKQPLLSSVVGRKVQMKPQTKVHLISVDSSQTSCPGSSGPFQVISVESNQSSSIEPSVPLPVVSVDSSHTRGFRPSEVQVVSVNTSQTISFGHSDTLHSIPIESKQTSGFGASSPLQEISVHSSQASSFRQSEPHVFSVNSSQMSGFPPSNRLWVSSVGSNQTTGLQSSDPLQVMSVESSQSSNIGSSEHLHVTSVESQQCSEPSDPLQVVSVDLSQTSGFRQSEVQVVHVNTSPTIGFGLSDPLQIIPVESNQMGGFGPMDLQVVSTDSRQSTEPSVSSSTMSSTSTLIKSDTMTPLRMPIEQHLASPPTRQVQTLLAPSKQRQTVLVKSCSFTQPHDEQSQTQSASCQSTLGEAVTVTRLRTPIKHFFDSPPKLQSQTSVTTLHPKQRVLARSHSFPQQVQASGVPHIPVQNEVFARAQALARSRLEKAKNHLDEHIQDVITVIRTRDKSKKQGKKRQAISRFLRPTVLETFLEALKGMGDFCSDAQLRDMDLLSQSVRTQWEVCATAADCSVHLEALRRIKESLESAESVLLSTTHQRTDTQRVEDIQHLTVSSSDLAPCQNSREDSVPLRETVLLEDLSLVHSQAVVQTNIVEIKQIAERTIIHPCLAQEEKATVEKAQSRYRDAQSVLHQQLLHNSQQLESDFPISPGSSITSISSDSLRSELQHLLALKDQTEALWCDFEIQFSQSSQHMEDGCNMEQERHQLIQQWREQQICVQARVKSIETTIELLESVDIQIALISDQLKQISQKPLNVRNFAVVDARNLHEELKCVDESIKKELFLLNERESLVGDGTDLSHIELQTHLPLQQTLHNRTKCLEQQRHCVQKSESALVALEKLLSHLQQLNDELNAHRTSDQSYSSVSFQKSLEQVREDSLQLDTMLDDAGLRITLDDKAGSCVEMVSALEEGFQVRLVEGQRVSDGGRKGREKQEKKEERAFGRKRMGLLVTLREVLAALERHVLKEPTLPALQHRLRFLTDMESKLHALRSEIDDLRDANTSDTNLSELQTQWETAHRSVTESREQCASLTELLKKFQSCRNNLGGTLQRAEQTIGDQASYMGKDNLQLLISKVISIKSDLSGLGDGVEEFRSVCRQLQSLVRRVLDCTDAPFESEADTLMDRWLDVTEKTDCYLDNLQAGFSLWEKLLLLAEEVEGWSAQKLMTLAQSNPFQTEVDVSALQNELKVQEENINHFHRRSSEIQELLQSQEFPLELQVIESQLRKKVAEVKELFFETKDVFRQLETAKMQVASEIADHLSSLQTITDNLNALNTSESTHALNSIQRLSEQLEVKAEQADALLQQMDLLASIAGLENLQTLSEAGAHLQESIRIAKELNIKKGEQTMNPNKPVTSQPVEESKHTEAHIEKVEDTTELQTVWDDKADEQSQRSKAKDAALEQKYFKEDILLSEDENWRVTPKERLTYAQSLSEPEVREDDSKMTSPCGSPKPIFTIVLDSDLSKSTQNLPAQTTSACSTQWHTVSVVHDRTTEKADESLTLEAKPSVSVAEEHAVLSTSDESLYSLYANLSTSGPLNENNPTDDSEPTCSVSDQDFKPKTEKGSSTKSLEQKISHTSIYHGSSKTAKKVFTIILDADSPELSLVQSQSLSQMQRSGTEFSRTDEFSHSNVKNQQRSSSRTEKALRKVAEKDNVKSSSSKTQEALQHNISEIMKTDIEKNEKEKQYEVMDVHKGGDSELGFLVHEQDVTMSESRDKAKKIPSAVPLNKAKTLQKPQNVAKGRKKIKKSGDAKKSDGFSGTKLKTSESEYKMTADSESRQTSEITVLATRDTSLNVSSTCSQSKSTEAKLTEAVDTKTLNLHTEAKQRHFGTVGVVKCASIEATEMSLGTGDIVQSKLTEKSMATEASPVMRAECITQIPAAIVDVNSTTLLSDSHQSLLQTQHTGLKDSKTKEFAYKDAKTQQRSSAGTVEPEEQEPERLLSKKYNVKSLSSVLQEALQPNTSEIMETDIEKRDKEKQHKVTDAETSSQIGACAEDNESGIKTLKQDVTMSDKHTFAEPSNDANALQKPPNVAKGRKKIKKSVDAVKKDNISSLKLKASTSEHKTKAELESLQTSEMKVPDTTDTSLNVASTCSQSKRTEDKHTEAVGTVQEDGLNLLQTEAKHGLFGTVAVSVVGGAPIEATDIGLETADIVQSKHTEKSMAADALPVMRAEGITQIPAVVVNVKSPTFSHQPLLQTQCTDYKDTRADVFAHKDTKTQQRSSAGTEKPEEQEHERFLLEKDIVKPSRSEILEALQINTSEIMETDIEKEKQHEVIDTDTLSQMCACAEDNESGIKTLKQNVTMSDKDTFAEPSNEANTLQNPPNVGKVKKKIKKSACAEKSDNISSIETQHKVTDTETSCQMNTRAEDNESGIKALKQGVTMSDKHTSAESSNEANALQNPPNGGEDTKKIIRLADIEKSDKISRRKIKASRSKHKNTDDSDSITFSEVTVPVTTDTLLNVSSTCSQSKSTENNLTHTVQETLTAKDGQFKTVSISHCRGAPTEGTDSLVSGAVETAQSTHCEKSTATDVSSVVRIETKTQISNLILDVDSPEISSHTQCEAPESPRSDEFALTDFRIQQRSSSGTEKHKKQEPEQNLLEKDYLKSSFSVIQKALQPNISEITETIVYDNEKDEQHEDISSEISSQISVLMVEGSKCGFVVHKQDKTMSESHGEADKITFAEPSSEANTLQKLTNIAKGRKKISKSALAEKSNKTTNRNQKTSRSEHNSTADSESLQTSEIILPDTTDTSLNVSSTCSQSKTTKSVSSEDKLSETVDTETLNLLQTEAKLGQFGTVGVVECAPIEATESVVLKTEDSVQSKHAEKSMPTDASQVMRAEHITQIPAVIVDVDSPPLLLSGSHQSLLQAQCTDSKGSREDINAYKDAKTQQRSSAGTEKPEEQEPKGLLLEKYNVKSSCLVIHEAFHPNTSEIMETDIEKCEKVKQHVVTDAETSSHMDARAEDNRSGIKTLQQGVTMSEKQTSGEPSNEANAHQKSPNVAKCRKKIKKSADAEKSDSTSSVKLTSQHKRTADSESLQTSEIIVPDTTDISLNVFSRCSQLKTTESLRSENKLTKAGNTVQEETLNLLHTEAKDGHFATDMDSETADIVESKLTEKSMPAVASPVMRAERITQIPAVIVDVDSPTLLSDSLQSQLQTQCTDTEGSRADVFSHTDVKTQQRSSAGTEKPEEQEPEGLLSEKDNVKSLSFVMQEALQPNTSEIRKTDIEKVKHVVTDAETSSHIDARAEDNRLGIKTLKQEITISEIQTSAEPSNEANVHQKTQNDGKGRKKIRKSADAEKSDNISTIKLVSRSENKSTTDSKSLQTSEIILPVTTDTSLNVSSTCSQSRTTKSVISEEKLTEALNTVQEETLHLLQTEARDGYFGAVGVSVVGGAHVEATDSVVLGTRDIVQSKHTEKSAPTEASPVLRAECITQIPAVIVDVDSPTLLSESYQSLLHTQCTGPKSSKTEEFSYTDVRNQWRSSAGTEGPEKQKPERLLSENDNVNSSCSEIKEALHPKTSEIRETGIEKSEKEKHHEVTDAERSSHMDTCSEDNESGIKTLKQDVTMSEKYTSREPSNEANTLQNPQNVAEGRKKIKKLADAEKSDNISTIKLTSRSEHKSTADLESLHTFEFMVPEATDTSLNVSSTCSQSKSTEDKLTEAVDTVQEETVNLLQTEVKHEHVETISFCAVGAVGDMQSTFTEDSGSMLTDAPPVVRAECITQTPTVIPSDLQLSHAEAQKTGDSDGSSLSQSEEMQRTNANPSARNKSTQNKGSEEDGEDQTRPLEQPAGTNIWTTLINATTTVQPLLMSSQCSEESWPKANSSFQNALLSEPDSSLAWTVLHVYRCQYRPAQLNIAHMTHQLEEAETCRQCVMEQVARLSHNECSVGHPTDSEKGMDARWSAVLLATSTMAELKKAQLQHITQYHQQKQALMITLDKLEAELSTLTLGCIESSTLQAEKLNAFLKNMQKNRGMLEDLLQTCSQISAHLGEAEGHVACIEPVRTCQERWQTLEQTAFRSLWCANICTTEASALLQESRELQFEMELLVKSVSSGHLSQGQIDWQNAIRDTMRAADLAVLTERCLYLHEVSQALFSSPLGKKEIRDVEDTIQALNSQLELTKEKIGCQTPNSSDHSAVVRIIRDYVTWAKQMESRISRRRRMSLFPEEASHQVNHMKKLQSETSLKRFQLASVLKEIREEVTELDEEESKAMLSTFDSLEELYNNTAKKTESALEEMNRTLLIRDRLWKQITDSSSWLTSVLEKESGKSVASEPKTTIPELRVQLQVCTEALKDAERQENNLETLLDDSKTMNNGLSLHESFQLIDRLAALQEEVSRVVNRRFASRWVIEELLHSQESSAEEQNVIQKSLRQIGADIMRQKYPVTRDSLLALESVKHMLMELLCKVPEVPHCPEPRRKEMLNAIVDLQRKIHLLELQAKEHEEYLTLKQQLENSREVMKKSLSQIVDSSLRDDVRVGFCQDVLAKLPLVRMACQETADKIEAISKDLYPSQLTAERQKIRLVVEQLASWEVTFKQEAKILECSVAERFGSPTDLSPPIQLFNSVRQRLKKTICLRPDKKTIDAELQNHWMVIQTIESVLRMLESSRKGKENESYKTTIDLGKKTLRDCSIYMDKLLQAQEALKHYHWAVQGAESFLQQIKSSLMISSTGFKNDREELRYIQQIFSSLAEGFQARLSEIGACVPQQTCLSIPLTEQLHIEVLSCFLVQDAKLEAQAQFQLEALQRRMRDQTVHLSHHEEMSQLLKNADSQISKCFSHKPTDPESCQVHQLKVKVLQTELKKLAESLEELREHCPGSRCSAPVDLMLGHLWRCWAVMKNRVEALKASTSHKEAEWRDFMIRLNKSKEGLHRLQTDLPDSSPLTGSLVDLQGFLSLTDHLQDGIEQEHQTLASLQHHVTRLLGVTNLQQLKESPQICQDLQSLLGHCRSLRDQSNSIRRELLFEMQEFGRVQEEMSSIQQNILSLLTVLQSESAAEHLQEVKVELVSQKARLQDVMERVMKRWRSVPSEIHILQNELNASLQEAKDKLAMVMEKSGPLRKMGEQIGEVTVGLLCVQGLLKQTSPNFSEAERTQKRIWDELDQWHTRIAELEGEVQDLAEQQPERAHILMDQLTQPLQLYQTTAKQAEHRTALISKIPACLQDYEALLSSTNCWLKEAEPWLLTPRTYTTAKCIHGHANSLKMMLDESEGYRAALETFMPSLQEISPVFDISPQKQLLHLGMQNITLMQQSVLEPLSHLQHLAAEMDAIEAEVKTMEKNVTKIRTILSASDTQNISPEEHLENIQVILDNVQSMKRTIDEIESCRPGLGLPAGAEQTLTVFSRSQELLQPIQELQQLSVQHSAALTASIGQPAELILPSDQPSEVPMPQLYSEDVKQMSVDGLYTEEEDEDSRSSSSGTLTCSVPEDPDETMVDEDIKSESAPALTEYDFKEPTTEIKKDFVTIEHESQDTEYCLLESSESSEKDSKPETEETNCLSALTSQHLQEFTNNNSLKPDATKIAEKNLNEYTETEMPDTESAKPGKDSGTKMPDTESAKPGKDSGTKMPDTESSKPGINLETEMSDTESAKPGIDSKITKLQSEEDLQKMSESGDEKEEPMNGEMSTRNSIKTTVHNEGLISKTLDTDPINVTDGDQTQTEAKPPDANASLGITESVSQEDAMLDLQIDVNETAVYQSSTPSQEHTLHQTTAVSKSEDQESLVQLLSSLKETSQDISSSETRQHPLDVPVSLLNATQTQDATKLLKDFSSTKNVQGGTWMLVIDQKKTAGQNTEEIQRCCEALLKGLQGLLDLGSDRLLRSQDEVPHNYSQLHNLLAGHKKYFQDMQQNLVMVKLLFQKLPEGAVQGQAEVEDLISDLLHRAQRQGIQMQQSSEKWSQYEEVSHRLHSRLDELETDMSSLNVEPKGDLQGQLRSYEKLHKILEDTCSQVWETEDCLRSLQKQGYCCERKFQTVSKSPLLMHWKHLHNQLQQKIQSTQKIRMNYERFQRDSTELEEWMRCAHEQLQKWKSFSGSDTPESRMAFTQLMEFFKDLEVRSAQKVSAESTGTQILQLTNSEAPDLRTRLANLQEEWTKLTSVLPALQQTQQELLEGQSDSQILADLSSWLQHIERRLEDESSGVHCALDSSELSRHLQALKHVKAEITNQQPCVNFLNHRCMKGAESMNESTNRSERILLAEQLGAFNLRWLLLQAKIGCVIHDVEDQWQACGDREKLLRCIHSWISQHMEWVKNSWRPGSCSQIEQTLQECEGTEKRLQVKSIELKGLEALHLFKQQDREHPGDQAFSRQLNSAIEDCQTLSQQINALRSDLQPIKDEWVRVESKMSAAELQTTGVIYRLELCRVPVFSSEQSRSHVEQIQELKRELNQPDIWTCSTEVLSNLKEKIKPFAFKLLSDRLEKERIRRHTVTEDVCEDLLKAQNALQLWLGYEHLTEECRVLLNQHWERLGELMNSSDREENTVEMLISRMQYISALEKDLTTLQSNVGKVMEASKLLIGQMQPQSAPLIKSETRLLSRDHVHLGRVLSEIRIQVQEELEEQRHFSTELKSIEKQVKNFESIMSSSTTSMERLKMVLLDLSGLNPNLAALNQRSLRCSLSSAEEERLQTLNTQWGQVFSQATERHRKMYGELLRDQNFQQKCQCWMELLDKMETDLANPTPGNCSSVRDLLAAHQRLKVEFLIGQPLQDAIINEALHFLESSQNEDRSSLLLRLTQLKTRWQETQQRLHQHETRLEELMGQWQLYEAGTRKLSRLFRHMEELLSPAGLAPCSLQQLQHSIKDFEWTEEQLQLHEGLYRQTVKAGGQIIPIVDTQMQKSLKTQLDALKDTWEPNSDLVQKRKALAYTITQNWKLCVTGLVDSALKLDEIKARLKSPLPEKIEDLKKHEQLTKEDEDLLQIWIVGLKELSTMKADVSQYVLPTDTALLQGQVEELHCQWEELCLKVSLRKQEIADRLNAWIIFNDKNKELCDWLTQMEKKVAHRGENLSIEEMVEKLKKDCMEEINLFSENKSHLKQLGEQLLLASDKAKETEIHGALRDVNDRWQQLFDHIEGRGKKLTETLVTVQQLDKNMNNLRSWLTRIEAELSKPVHYSICHREEIQKRLAEQQDLQRDIEQHTERVASVLTLCDVLLHDEDACSSDGENDSIQQTTQRLDQRWRNICSMSLERRLRIEETWRLWCKFQEDYSCFEDWLNAAERTAAEPNSSDVSYTDAKEELHKYEVFQMRVHESLTQLEIINNQYRRLAWENRTDAASRLRAMVHQGNQRWDALQRRVAAILRRLRHFTGQREEFEGTRESLLVWLTEIELQLTDMEHFSESHHQDRMKQLKSFKKEITLNTNKIDALIVFGEGLIQRSAPLDAVVIEDELEELHTYCQEVFGRVARFHQRLTSLRPLQEHPDVYDGERSRETQSPPSSSQPSMCLLSPPQERSGRETPVSVDSIPLEWDHTGDVGGSSSHDEEEEDAAFFSALSGQNWHFQNMPERKSFQLESSSPTHTSTPFKQGYVQLMSECSGSIKSVKRVSMILDDEEQQEEQGLTGLNTADKQSGVIERWELLQAQAVSKEQCRTRDPQQLTSDLHDITSWLDCITLELDMLQRPETSASVEVLEERVKQLKEMQKTFARYKTMMLSLNLCGRELQQEASGGAPELQEGLHSMNQRWTEACAGLERWEDSLRNTLVRCQEFHEMVHSLLLWLAHAESRRYAVNMNDASVQLSTLQEHTQTLKDLAVDLQGRQKQVNSLQDIASELLPEAGGEDSTEAKEKLHVIGSKLRLLSRQVEQDLQTIQERLGSTTDASGDQKSPECSRWNGEPSPQRSFFYRVLRAAFPLHLLFLLLLVLACLVPLSEDDYSCTLSNNFARSFHPMLRYTNGPPPT", "length": 8895 }, "evidence": [ { "id": "FB:FBgn0261836", "url": "https://alliancegenome.org/gene/FB:FBgn0261836#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0LEP2-1", "protein_name": "Nesprin-1", "gene_name": "Syne1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATSRASSRSHRDITNVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGIKLLALLEVLSGQKLPCEQGHRGKRIHAVANIGTALKFLEGRKSMYRGSPIKLVNINATDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSMVSTETASPPSKRKVATKVQGNAKKTLLKWVQHTAGKQMGIEVKDFGKSWRTGLAFHSVIHAIRPELVDLEKVKNRSNRENLEDAFTIAETQLGIPRLLDPEDVDVDKPDEKSIMTYVAQFLTQYPDIRGAGYDVQENDRDDRLILKEAKVWIEQFERDLTRAQMTESNLQDKYQSFKHFRVQYELKRKQVEHIIQPLQRDGKLTLDQALVKQCWERVSSRLFDWHIQLDKSLPAPLGTIGAWLYRAEVALREEITIQQVHEETANTIQRKLEQHKDLLQNTDAHKRAFHEIYRTRSVNGIPMPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVELLLQSYISFIENSKFFEQYEVTYQVLKQTAEMYVKADGSVEEAENVMKFMNETTAQWRNLSVEVRSVRSMLEEVISNWDRYGDTVASLQAWLEDAEKMLSQSENAKKDFFRNLPHWIQQHTAMNDAGNFLIETCDEIVSRDLKQQLLLLNGRWRELFMEVKQYARADEMDRMKKEYTDGTAALSGFAAEAHRKLSEPLEVSFMNVKLLIQDLEDTEKRVPVMDAQYKMIAKKAHLIAKESPKEEANEMLTTMSRLKEQLSKVKECYSPLLYEAQQLSVPLEELETQITSFYDSLGKINEILAVLEHEAQSSALFKQKHQELLACQESCKKSLTFIEKGSQSVQKLVTSSQALKHWDHTKLQKQIADVHHAFQNMIKKTGDWKKHVEANSRLMKKFEESRAELEKVLRAAQEGLEEKGDPEELLRKHTDFFSQLDQRVLNAFLKACDELTDILPEQEQQGLQEAVRKLHKQWKDLQGEAPYHLLHLKIAVEKDRFSAAVEECRAELERETKLASQEGSEKIIKEHRVFFSDKGPHHLCEKRLRLIEELCVKLPVRDPVRDTSGACHTALKELKASIDNTYMMLMDDPDKWTDYASRFSELSSWVSAKESWLKNIKDQPIDTGNHDEVKRVADEMRNDITKKGEILSWLKSRLKHLIDVSSENEAQKRGDELAELSSSFKALVALLSEVEKMLSNFGECVQYKEIVKSSLEGLMSGSEESKDEAETILDTENLFEAQQMLLRHQQKTKMISAKKRDLQQQMEQGQQGGQAGPGQEELRKLESTLTGLEQSRERQERRIQVSLRKWERFETNKETVVRYLFQTGSSHERFLSFSSLESLSSELEQTKEFSKRTESIATQAENLVKEAAEMPLGPRNKRLLQQQAKSIKEQVKTLEDTLEEDIKTMEMVKTKWDHFGSNFETLSNWITEKENELSSLETSASAMEMQINQIKVTIQEIEGKIESVVGLEEAAQSFAQFITTGESARIKAKLTQIRRYWEELQEHARGLEGVILGQLSQQQKFEENLRKIQQSVSEFAERLAEPIKICSSAAETYKVLQEHMDLCQALESLSSTVTAFSASAQKVVNRESSTQETAALQQQYEEILHKAKERQKALEDLLAHWQRLEKGLSPFLTWLERCEAIARSPEKDIAADRVKVDSELQLIQALQNEVVSQASLYSNLLQLKEALFSAASKEDVAMMKLQLEQLDERWGDLPQIISKRMLFLQSVLAEHRQFDELLFSFSVWIKQFLSELQMTSEINLRDHQVALTRHKDHATEIEKKRGEVKHLQGHLAQLRSLGRAEDLHPLQSKADDCFQLFEEASQVVERRKLALTQLAEFLQRHASVSTLLHQLRQTVEATKSMSKKQSDSLKKDLHDAIQDVKTLESSAIGLDGTLTKAQCHLKSGSPEQRTSCRATTDQLSLEVERIQNLLGTKQSEADALLVLKEAFQEQREELLRSIEDIEERTDRERLKEPTRQALQHRLRVFNQLEDELNSHEHELCWLKDKAKQIAQKDVALAPEVDREINRLEATWDDTKRLIHENQGQCCGLIDLVREYQNLKSAVCKVLEDASHVVEMRATIKDQEDLKWAFSKHETSRNEMNSKQKELDSFTSKGKHLLSELKKIHSGDFSLVKTDMESTLDKWLDVSERIDENMDRLRVSLSTWDDVLSSRDEIEGWSNSSLPQLAENISDLNNSLRAEEFLKELESEVKNKALKLEELHSKINNLKELTKNPETPTELQFIEADLRQKLEHAKEITEEAKGTLKDFTAQSTQVERFVKDITAWLVNVEESLTRYAQTYTCEGLKKVKDIRKELQSQQNNIISTQEVLNSLCRKHHSVELESRGRAMTGLIKKHEATSQLCSQTQASIQDSLEKHFSGSMKEFQEWFLGAKAAARESSNLTGDSQVLEARLHDLQGVLDSFSDGQSKLDAVTQEGQTLYAHLPKQIVSSIQEQITKANEEFQAFLKQCLKDKQALQDCVSELGSFEDQHRKLNLWIHEMEERSNTENLGESRHHISEKKNEIHKVEMFLGELLAARESLDKLSQRGQLLSEESHGAGKGGRRSTQLLANYQNLLRVTKERLRGCQLALQEHEALEEAMQSMWSRVKDVKDRLACAESTLGDKETLEWRLSQIQDILLMKGEGEVKLNLAIGKGDQASKSSNKEGQQAIQDQLETLKKAWADAMSSAVHAQSTLESVIDQWNDYLEKKSQLEQWMESVDQKVEHPLQLQPGLKEKFSLLDHFQSIVSEAEDHTGALQQLAAKSRELYKKTQDESFKEAVQEELRTQFQDILTVAKEKMRTVEDLVKDHLMYFDAVQEFTDWLHSAKEELHRWSDTSGDSSATQKKLSKIKELMDSREIGAGRLSRVELLAPSVKQNTAASGCELLNSEMQALRADWRQWEDCLLQTQSSLENLVSEMALSEQEFSGQVARLEQALEQFSTLLKTWAQQLTLLEGKSTDEEIVECWHKEREILDALQKAEPMTEDLKSQLNELCRFSRDLSPYSGKVSGLIKEYNCLCLQASKGCQSKEQILQERFQKASKSFQQWLVNAKITTAKCFDLPQNLSEVSSSLQKIQEFLSESETGQHKLNTMLSKGELLSSLLTKEKAQAVQAKVLTAKEDWKHFHANLHQKESALENLKIQMKDFEVSAEPVQNWLSKTKRLVQESSIRLYDLPAKRREQQKLQSVLEEIQCYEPQLHRLKEKARQLWEGQAASKSFVHRVSQLSSQYLALSNVTKEKVSRLDRIVAEHNQFSLGVKELQDWMSDAVHMLDSYCLPTSDKSVLDGRMLKLEALLSVRQEKEIQIKMIMTRGEYVLQSTSPEGSHAVQQQLQALKEKWESLLSAAIRCKSQLEGALSKWTSYQDDVRQFSSWMDVVEVSLTELERQHTELREKVTTLGKAKLLNEEVLSHGSLLETIQVKRAAMTEHYVTQLELQDLQERHQVLKEKAKETVTKLEKLVRLHQEYQRDLKAFENWLGQEQEKLDRSSVLEGDTNAHETTLRDLQELQVRCAEGQALLNSVLHTREDVILSGLPQAEDRVLESLRQDWQVYQHRLAETRMQFNNVANKLRLMEQKFQEADEWLQRMEEKISVRNERQSSRSAKEIQLLQLKKWHEDLSAHRDEVEEVGSRAQEILDESRVSSRMGCQATQLTSRYQALLLQVLEQIKFLEEEIQCLEETESSLSSYSDWYGSTHKNFKNVATKIDKVDEAMMGKKLKTLEVLLKDMEKGHSLLKSAREKGERAVKFLEGSEAEALRKEIHAHMEQLKNLTSAVRKEHVSLEKGVHLAKEFSEKYKVLTRWLAEYQEILLTPEEPKMELYEKKAQLSKYKSLQQMVLSHEPSMNSVQEKSEALLELVQDQTLKDKIQKLQSDFQDLCSIGKERVFSLEAKVRDHEDYNTELQEVEKWLLQMSGRLAAPDLLETSSLETITQQLAHHKAMMEEIAGFEDRLDNLKAKGDTLIGQCPDHLQAKQKQSVQAHLQGTKDSYSAICSTAQRVYRSLEYELQKHVSRQDTLQQCQAWISAVQPDLKPSPQPPLSRAEAVKQVKHFRALQEQARTYLDLLCSMCDLSNSSVKNTAKDIQQTEQLIEQRLVQAQNLTQGWEEIKNLKAELWIYLQDADQQLQNMKRRHAELEINIAQNMVLQVKDFIKQLQCKQASVSTITEKVDKLTKNQESPEHKEISHLNDQWQDLCLQSDKLCAQREQDLQRTSSYHDHMSIVEAFLEKFTTEWDNLARSNAESTAVHLEALKKLALALQEKKFAIDDLKDHKQKLMEQLSLDDRELLREQTSHLEQRWFQLEDLVKRKIQVSVTNLEELNVVQSRFQELTEWAEEQQPNIVEALKQSPPPGTAHHLLTDHLAICSELEAKQVLLKSLMKDADRVMADLGLNERKVIQKVLSEAQKHVSCLNDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIMFREYVCLLPDDVSKQVKTCKTAQASLKTYQNEVTGLWTQGRELMKGITEQERNEVLGKLQELQSVYDTILQKCSHRLQELEKSLVSRKHFKEDFDKAQHWLKQADIVTFPEINLMNERVELHAQLDKYQSILEQSPEYENLLLTLQTTGQAMLPSLNEVDHSYLSEKLSAMPQQFNVIVALAKDKFYKIQEAILARKEYASLIELTTQSLGDLEDQFLKMRKMPSDLIVEESVSLQESCRTLLGEVVALGEAVNELNQKKESFRSTGQPWQPEKMLQLATLYHRLKRQAEQRISLLEDTTSAYREHAQMCQQLESQLEVVKREKAKVNEETLPAEEKLKVYHSLAGSLQDSEILLKRVAVHLEDLSPHLDPMAYEKGKGQVQTWQEELKQMMSEIGEMVTECESRMVQSIDFQTEMSRSLDWLRRVKAELSGPVCLDLRLQDIQEEIRKIQIHQEEILSSLRIMSALSQKEQEKFTKAKELISADLEHTLAELKELDGDVQEALRTRQATLTEIYSQCQRYYQVCQEANDWLEDAQEMLQLVGNGLDVESAEENLKSHMEFFKTEGQFHSHMEELRGLVARLDPLIKPTGKEELAQKMASLEKRSQGVIQDSHTQRDLLQRCSVQWQEYQEAREGVIKLMNDVEKKLSEFVVTKISSSHEAEEKLSEHRALVSVVDSFHEKIVALEEKASQLEQTGNEANKATLSRSMTTVWQRGTRLRAVVQDQEMILEDAVDEWKALSAKIKENTEIINQLQGRLPGTSTEKTSKAELIALLESHDTFAMDLERQQLALGVLQQRALSMLQDGALPGPKEEVPTLQEITALQDQCLNMQEKVKNHGKLLKQELQEREAVETCINSVKSWVQETKDYLGNPTLEVDTQVEELKSLLAEATSHRESIEKIAEEQKNKYLGLYTILPSEISLQLAEVALDLKIHDQIQEKVQEIEQGKAMSQEFSCQIQKVAKDLTTILTKLKAKTDNLVQAKADQKMLGEELDSCNSKLMELDTAVQTFSEQHGQLGKPLAKKIGKLTELYQQTIRQAENRLSKLNQASSHLEEYSEMLESIQKWIEKAKVLVQGNIAWNSASQLREQYILHQTLLEESEEIDSDLETMAEKVQYLANVYCTGKLSQQVTQLGRETEELRQAIRVRLQSLQDAAKDMKKFEGELRNLQVALEQAQTILTSPEVGRLSLKEQLSHRQHLLSEMESLKPKVQAVQLCQSALRIPEDVVTGLPLCHAALRLQEEASQLQHTAIQQYNIMQAGATAQRVQPAGPTLEAVVQYEQYGQEMKHLQQLIEAAHREIEDKPVATGNIQELQAQISRHEELAQKIKGYQEQIASLNSKCKMLTMKAKHATMLLTVTEVEGLAEGTEDVDPELLPTPSAHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEISSPPACRSPSPVANTEASVNQDIAYYQALSAEGLQTDAARIAPSAAASQELYEPGLEPSATAKLGDLQRSWETLKNVISEKQRTLYEALERQQKYQDSLQSVSTKMEAMEMKLSESLQPGRSPESQMAEHQALMDEVQMLQDEINGLQASLAEELVAESQESDPAEQLALQSTLTVLAERMSTIRMKAAGKRQLLEEKLNDQLEEQRQEQALQRYRCEAEELDHWLLNTKATLDFAAGIPQEPMDMDAQLVDCQNMLVEIEQKVVALSQLSVRSENLLLEGKAHTKDEAEQLASKLRMLKGSLMELQRALRDRQLNMQGVTQEKEENDVDFTATQSPGVQEWLAQARNTRTHQRQSSLQQQKEFEQELAEQKSLLRSVASRGEEILIQHSTAEGSGGLGEKPDALSQELVMEGAKSFAEDQMRAKWESLHQEFSTKQKLLQNILEQEQEQMLYSSPNRLLSGVLPLRGEAQTQDKSSVTSLLDGLSQAFGEVSSQSGGTDRQNIHLEQKLYDGVSATSTWLDDVEEHLFVATALLPEETETCLFNQEALAKDIKEMSEEMDKNKNLFSQAFPEDSDNRDVIEDTLGCLLGRLSLLDSVVGQRCHQMKERLQQVLSFQNDLKVLFTSLADNNYIILQKLANMFKQPIVEQIQAIQQAEEGLRELDGGISELKQRGDKLQVDQSALQELSKLQDMYDELLVTISSRRSNLNQNLALKSQYDKALQDLVDLLDTGQEKMAGDQKIIVSSKEEVQQLLSKHKEYFQGLESHLILTETLFRKIVDFAAMKETQLHSDRMAQASAVLKQAHKRGVELEYILEMWSHLDENLQELSRQLEVIENSIPSVGLVEESEDRLVERTSLYQHLKSSLNEYQPKLYQVLDDGKRLMMSISCSELESQLNQLGERWLGNTNKVSKELHRLETILKHWTRYQSEAADLIHWLESAKDKLAFWTQQSVTVPQELEMVRDHLNAFLEFSKEVDAKSSLKSSVTSTGNQLLRLKKVDTAALRAELSCMDSQWTDLLAGIPAVQEKLHQLQMDKLPSRHAISEVMSWISLMESVILKDEEDIRNAIGYKAIYEYLQKYKGFKIDLNCKQLTADFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNKSWQLLQGRVGEKIQMLEGLLESWSEYENSIQSLKAWFANQERKLEEHHQIGDQNSVQNALKDCQELEDLIKAKEKEVEKIEQNGLALIQNKREEVSCSVLNTLWELRQTWASLERTVGQLKIQLTLVLGQWSIHKAAFEEISNHLMEARYSLSRFRLLTGSSDAVQVQVDNLQNLHDDLEKQEGDLQKFGSLTNHLLKECHPPVAEALSSTLQEVNMRWNNLLEEIAKQLHSSKALLQLWQRYKDYSKQCASAVQRQEEQTNALLKAATSKDIADDEVAKWIQDCNDLLKGLGTVKDSLFILHELGEQLGQQVDDSAATTIQCEQLCFSQRLEALEQALCKQQAVLQAGVVDYETFAKSLEALEAWIVEAEGILQAQDPTHSSDLSTIQERMEELKGQMLKFSSMAPDLDRLNELGYRLPLNDKEIKRMQNLNRHWSLISSQTTERFSKLQSFLLQHQTFLEKCETWMEFLVQTEHKLAVEISGNYQHLLEQQRAHELFQAEMFSRQQILHSIIVDGQNLLEQGQVDDREEFSLKLTLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYREMAEKLRKWLVEVSHLPLSGLGSIPVPLQQVRTLFDEVQFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELTDIQEKWKSASTHLEEQKKKLAFLLKDWEKCEKGIADSLEKLRTFKKRLSQPLPDHHEELHAEQMRCKELENAVGRWTDDLAELVLLREALAAHLSAEDISILKERVELLQRQWEELCHQVSLRRQQVSERLNEWAVFSEKNKELCEWLTQMESKVSQNGDILIEEMIEKLKKDYQEEIAVAQENKIQLQQMGERLAKASHESKASEIQYKLSKVNDRWQHLLDLMAARVKKLKETLVAVQQLDKNMGSLRIWLAHMESELAKPIVYDSCNSEEIQKKLSEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLEISERTAAFPSSSGVLYTVAKEELKKFEAFQRQVHESLTQLELINKQYRRLARENRTDSACSLRQMAHGGNQRWDDLQKRVTSILRRLKHFISQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNHSKIEQIIAQGEQLIEKSEPLDAAVIEEELDELRRYCQEVFGRVERYHKKLIRLPLPDDHDLSDRELDLEDSMALSDLHWQDPSEDGMPSPQPSSNPSLSLPQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESASRTLPSEDEEGEEDKEFYLRGAVGLSDVVIPENPEAYVKLTENAIRNTSGDPTSLESQMRQLDKALDDSRFQIQQTANILRGKTPTGPDLGTSYKGYMKLLGECSGSIDSVRRLEHKLAEEESFPGFTNPTSTETQPAGVIDRWELLQAQAMSKELKMKQNLQKWQQFNSDLNNICAWLGETEEELDRLQHLALSTDIHTIKSHIKKLKELQKALDHRKAIILSINLCSSEFTQADSKESHDLQDRLSQMNRRWDRVCSLLEDWRGSLQDALMQCQDFHEMTHALLLLLENTDRRKNEIVPIDSTLDPETLQDHHTQLTQIKQELLKSQLRVASLQNMSRQLLVNAEGSDCLEAKEKVHVIGNRLKLLLKEVSRHIKDLEKLLGMSSSQQDLSSWSSADEVDTSGSVSPTSGRSTPNRQKSPRGKCSLSQPGPSVSSPKSRSTKGGSDSSLSETRPARAGRDFLFRVLRAALPIQLLLLLLIGLTSRVPISEEDYSCALSNNFARSFHPMLRYTNGPPPL", "length": 8820 }, "evidence": [ { "id": "RGD:620546", "url": "https://alliancegenome.org/gene/RGD:620546#orthology", "database": "AGR" }, { "id": "HGNC:17089", "url": "https://alliancegenome.org/gene/HGNC:17089#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-071218-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-071218-4#orthology", "database": "AGR" }, { "id": "MGI:1927152", "url": "https://alliancegenome.org/gene/MGI:1927152#orthology", "database": "AGR" }, { "id": "FB:FBgn0261836", "url": "https://alliancegenome.org/gene/FB:FBgn0261836#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M9MRD1-1", "protein_name": "Muscle-specific protein 300 kDa", "gene_name": "Msp300", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MADSGGPGSKHMDPTTIDAGGGGAGAAGGDDVPPVPAVRRRRAHEQKSSREQVLEEEKSQQLETSTVTRTYMKTITTSLTTSSSSNVEEFILGEHAAGAAAAPSPNQQRLRQKVAQYEKVWSDGSSPVKRPAEQSSDELRLTDDQDEYDAENPFEIDVHEIERRLRQERQRGLAEAEAAKLAFQQVQLRHTTPPRRVEVTSDQVASPFNVTLRTTSRMSPGAEHGNVEEHLAPFNVTLRTTRRTKKKEFKELENFLEGERTVREVPSADGVRTIITSSMTSDGGYAEEKIYRHGEGYVSPRDSPSWSRSSYSSERSSVTPPRSVDLTAGGRRILIKLEQESELTEENQTRDETDLSFGRQEVAMATGNIDITVGGSNPRRRLYQQTTVQVGGGNRTSPQDSTPQRPRDLDLAGTTKTMLTSTPIGTKEQPQTGPKTLVSPAATCQLRGSSTEEPRKIVSHKTITSTTTKSTSSSTSATSSSSTSRKLIETSPVVVGKIAQIRTGKSNASDNDIDIDNDSDTEGRPASSIVIVSTPTRPTTPATASVSASAVTPSASISATAAHALSGIGTFSKSLRQDYQTLATQSGRSNESPSDQEYQEFQSTMASINYARSNSQYDSHIKEKREEQERVQKKTFTNWINSYLLKRVPPLRIDDLINDLRDGTKLIALLEVLSGERLPVEKGRVLRRPHFLSNANTALQFLASKRIKLVNINPADLVDGRPPVVLGLIWTIILYFQIEENSRNLEYLGHGIGGSVSSLDSVGNQKHGDLKAEKWKQGARKTLLNWVTNALPKDSGVEVKDFGASWRDGVAFLALIDAIKANLVNLAELKKTSNRQRLETAFDVAESKLGIAKLLDAEDVDVPKPDEKSIMTYVAQFLHKYPEPKGASRDQSHVQQEADELRRFLVEKTTEYEPMVMMSSFPRDFGEYLLARSEVDAHLAAYNRLKQLIESQSGFLQVSRQSWEEINELWQRLQYQMMYWLWLLDSELPGDFGTVGKWLAEAEKLLMDNDIPNAMNEETAAVISRKLEEHKLFFADLPRILAMFDNAKRSPVAQQIPLEQLRNMERRLQEVGPKAAERRIRLKFLEHKCCLIAFLNLVENKMRGWTGKYGHEEKVAQQLEQYKNFVSRNKIFQEFQKAFVDMQQVVEEYKRDGNVPRKEINDIDRFMYETEERWKRVSMELKCCQNSLEEVVNCWRSWNQLAPTCEEWLQLAEQKVNQSEDERLDFFQDIPVWKDKFDALASSANYLIASCEEPIAQQLRQRHGALSERFERLFANTKQYMHAGDIIRSRQEYKSGIEQLSRWLRGAESVLDQRQVLGNSEQVKEYGQQLQQLASEIDDNEELFKTISRNFQSLIQDLSRDEVDKMMKLLKQEKESLVRIRAQLPAKLHLFHQLQIQQESLEAGQKEIHQWLSEAEQLLGTHNLSGGRDAINEQLHKHKTYFSRTVYYRSMLESKNKVFQNLLKAVSSDDKIDTAPASQQMQQLNERFNYVIQNAQQWEQRLDSAAGGWSNFKDNERVVSEWLTQAESMLVEKHIESKTTIETQKYFFEQVNDRWMNDLVQSAQQLLTTLPAQEQPAVVHSVEQLQSRWKNVLSQAPLHLLKLEFRLDENAFYQSLKDVEKELQLEQQALNRNEDVDSILQRNQQFLLQQDVVPRLERCLQNMQRLAQAHRQQQPGDISLDQAYDNAKSQWQLLSNKLGDMRQTLQQIPAQWQGYHLKFNDMVDWMNGVDQSLKNIVNEVNTMEEFEKEKVVFQKICQDADNKREDMKWLVKTLDSLLSYATEDEANLEQKKLEDLIARYKNLIPTIEITMVKTEVFSKCYTYRREVHEVVCLLSKVKDQTANIPAPDSLDRVNRLIEEQQYAINQLDHQRPHIMSMLQRGRDLIKDVHAPAFVNAEVKNLETGWNQAYTETSDKLQALKGTQAVWSEFVDQKNDIFSMLQTAETELRSLTPLQTDPKNVSQDLKSKRDLNVQLQQASHQLLPKLHALKSELAPLAAPDKRPILEKEVTEVEKMFFNTMEHVKDRVGYLEDYSAKWNNYKTRLAELQEWANKVAPKNIEALQSEDLTPEERVVKVQAFKRILGDRMKQLDLLAADASELAPKEGNIAEAKRLKGEITKLQEVLSAINRNVDHQAQAVQEDLVNWQQFQAGLQQIKPAVEQSEVKVNNVVSKPISLEEAVAMQQNAQQFETQCQEQLDKLHGISNISHKMLCKTNAPDELDAMHSRWTAVHENAKQASAKLEKLVANWKSFDADAAKLEDWVGQGEQQMSRRPAVLNTPHIDKLEKELVKLKSFNNEISQQQAKLVTLGQNADQISLHLAPEGAAALKDRVNQMKGKLQKLSEATRGHINEVSDAIISRQDFNAKLVNFSNWMEQLRNQVTQVEEINPERVETSLHVIHALLQEHADKKPSFNAIYDEVKQLALGATPEESNALNDAYTALVVNYQNLETNMLQKKAALEKWTELLGWKNDTESHLNYLKHQLDKPEGPAAEELSKVIDEIDNLGQGIGYWKGQAKEIDENPAIQLRDALSRRPLIATQIVNDVENKLENLKLRSQSQQQQIQQMTVRKDKFHALEHNFGQALQENRAKLDEILRQHPTLNNIDQIIADLVALNDALKYQADLKNRIHDEGSLLMREDIASMPAIQESLLIMDKNYDSLQNEIADRIQKYNLISQALREYADSKDKFSKELKKAEDLYNAIPQQPRDETELHQASEKTRKTMEQLRKSKLSLDELERRGNNVGKLFSAIGEPIPQEVPQEVTAAKQHWQDLHDKTAKNAHVYETEAVIWSQIEDAKKDLLPWLSETNQGLCDAADNSIEIEFGPMRLSKYRTELPSYQALKDSIVEKTNDLVKINKGAEIPALSALNKLLSEQFAEVNNNADRLSAITTSFNDQEQELRRRSKEAGERVSKLREQLIKCDDMSGDNNKIMERLQQCRALRGELDNSGNEIDNIKQKVDELRNLYPTFSESIIPKELNNVQKRYENVDLYAKKIESSLLQFLKKFHADKVGMLKRIIATQREKVAWCQPESSSDKYNLDVKKSSLQEVSKSIDDCKARHAETLKSLEMLKAVESPQNLAELTSDAELLRKDMQALQDSFDQIKGILDENVDLWSQYEQSNEQISNWLRDVEGRVKAETSSQVNLSEVPQKLQELSILQQDVLAHEPIINNLEQTSQQLIEKNPEARIGQFVTHLVQRYQAVSKALTSYIDKIRGAQLSNANFAKAAKDFNEWFGDAKIEFQELARMGSPGSSSATAQQLQTVKNYIKTFDNGQILLNNAVDIGEALYPVVSPDNRERIRADLRQMREKFDYLRDEANAFMQQVEGVLIQKTSIEESYTQVSHYLNESKAKVPTTDELYPTLATKKAALQNYKTQLQEITLHKNALKQLHDKAVTLCDDESERKTDESIQEYNTLSKKISDRITTVGNHVVKHEAYDQVLEKAQDWLNTIKSEAIDILNETTFEKEGAEEKLLVVENLLQHKPEGDSIFDTCHKLLETVLTQTHPSGHPALLKGFEEPKQSWEDFMTLCQDSLVKLKQLCSKWDEFDTIIEELDNWMKNVEAVVKNQNLKSTAEAKNAHLKQLQDISKDIERRGAAINELMDQGREIEGETDLNLKLSRLNTRYQTLKNLCKESIAKYVNYVKDHESFDKDFDSFKQNLQSSVDELAKTNEIVGDQSVLQDQQNKLREMSDKRILDSTLFEGLIDRGEKLYGHTSPEGREIIRQQLRALRTLWDNYTDDLNSATQKIDQCLLQFNEFSIAQDQLTKWLKDVDKAMQSHTEPKTTLQEKRAQLQNHKLLHQEITTHNVLVDNVCDKAQILVDQIKDNSLNVYLTSIKQLFQSIVQKSDEILHNLDDCVQKHNELNNALSSAKTWISNEKAKLLECDDAYGEKADIKRKIETLGQLAQNKPQAMKIISDIRDLFEKVKATTSEKGNEVLDKEIEELETTMKSHFDDIEGIEGKQKDVLAQWDKFEKALEELTKWCRSAEAVFREQQLQSTLHEKVEQLEKYKIQRELILQKEKEIDAFGDAAHALLNNCGADRLKTLTTQITNRYQLLQVLSKEVVNRWSNLVDDHQFYQDKYNEVDLWLQPIESQMAKVLLDEPTQSSNILQVLLSEKEQAESLFAALNAAGEKALPETSTQGREKIRKDLRDIRDRWDKLDEGIRNLEKRQEAQGVQLSSYQDILNQTVNWLDQVEKLIHNENPASWTSAQEIRSKLYKYKATNQDINSHKRIVEAVNEKAAALLGSAAPANADEISKAVAEVNKRYDQVGQDCAKLVADLDGAFDVYQQFSELQKAQQDYQKNLWDRLTGYSDYSGNKAALQARLQKINEIQDALPEGVAKLKSLEDHIEQQASNIPARSKEVMARDLANLHADFEKFGASLSDVKSGLENRLQQWNDYEINLDRLITWLGEAENSLKNYNLKSSFEEKEEQLNGFQSLAQNLRQNEADFDKVKDDTSELVQSSGETRIAVNVQQVSSRFQSIQATAKEILKKCEQAVQDHGHFNDKYKQCADWLANAQARYDDCCDLSTVASRDDLLKKQVVIQELLAQQPTATQLLNSTVELGEKCYGSTATEGREAIRSQLDDLTFDQLFDNIAITARKIQDKIAKWSGFDEIADSLKSWLDETENALPADIELKTTLDEKRNKLQTYRDILNDINNHQVELGNLQEIAANLPEKTELVDQIIKDISDRFGKLQKRAQNYVERYEGIVSAHQQYSKAVMDAQEFIDATLNTVHYWGDLDLEQISLHTNLDRLKNLKASLADEFPRVDQVRALGEKVIPGTVDVGQVNIKSQIDTTQQEWESLLTTISSTIEAIEARLQHWSEYEQLRDQCLAWIRDTDNNLHAIDLKEDLPKKRAQLDALKALQGDVRAKELEVDNVTEKAQTLLKGPSSNRASGPELVTKYQQIFHKVKELNNRWQQYVTSHEDFDNAISDCSSWINEIKEKLDYCSDMSSMSPKELDKKLATIQDVILLKDEGSARVLKILEQAQHVLANTAPGGH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LATLSEQIKELPTEQRILEVNEGLKDLDVAIKNGDKTVIQTTVITVIEKVSTWLETIEYRVYLIRQNSNEGPSEEKLDNYNQLNDELSTIKQNVVQLERQLSKAEPEPQLLQCVDSLKEHVDAVEQVTQQNQVQDSNDLDKWHNFEVLLYNVSSVLADLQQSYDLLINQEYPLSAKLAQLDELEQQHEAAQQQLAHLCQNARAFQRDFPGKKMPQDVHNAFETSKNIANNIQAERERVLQLQSLAEEYEQTLKEFTKITVLADKLVESPIVSSSLEQLNNEVQKQRKFFVNLSHCRAMLESLEENIDSETREKHSELHKELYNRATSLLDKASERSSKLVQAASRWTVLEKGMRDELQWLQVAQQRVPDLSAVTSADYDQYTTLYQSLSNDISHHYVKMTQLSGIANKLQLLVQAPNLVEETNEALIVLLKLREEVALYLHRLLVFKEIWVQYEQQTDKLEAFVREAEQELRNIQIPSQPTHQPIEHMRQFWEIKARFELHNNVRTDTGLSFEKSLQVIPLADEMLQRQFHAQLEDRWQAVAQAIELIQHNIVECLSSEDVPADEKLKMVERELQEIYLTMTSMKGVIKNEEELCLYIERVQVLRTRVGFIGNELGRIGLQEPAIEPEKVGELFSLSHKISTQIAEELEGASVLRDQLQAIQEGISNQRKHQAKISVILDECEAAERQGADVLEKAVADCQAAGEELVISWQEIMRIRQMLHTLPMRLKMSVSPVKLERDISQLQDDHAFLESKCTNIMAILRSRLAVWLRYERQLELVHGSVQETDFMMELIRVHGQVDYERLRKATERLEGLAGDLHNREQLIDELKGAAKPLIESCDVQIVEQIESAVQEAVVAWNDTSENLQQLRTRYQRAVELWDKYRNASAAVKNSIDQQMDAVKSLEQPLDALQHAKVCQDNLTTQNDRILELRDIVAKIAADVGLDASALMQGELDALGQRLAECKDAITTLANVAETQDKERKELDKEVTLAKAYFNNVQQDISREAPQNPKESEEQLAALRAHLQTLARTEEQLRQLKERHQNSEVAPSVASSDDDGILEVLALWQKIFQDTFQEYHRLSTRLARSQNSSEALRLWRQYLQHVQSFLSCAIPEDYSSLREQQQLCAIHQNLLISQQSVLSETPLESELSEQYKALTNLHNETLSRIMQRNGELERRVSGWNAYRQQLAALLDWLRQREAERNALQLRYIHLKRVPHLKHRLDAMIQQLDQGEQQSKALQEQQQELARHCDDALATAMRMEQASIGQRISNLRAALKTWQGFLQRVTQLSESYEQRVNQLQQEFGAAQKLLDANSESLPTQPAAIEQLLGSLRAQRVQLGAQVSALESLTVTQEELKECISPHDMKTIRQRNWLLWQQHADLDYQLANLINSIEERLSLLSNYQIRYDRISQWLQRLEQRVEKDADVTAMTNPEQAAKQLEQQVNSELQLRDKEREWLLSTSRELLTLYSEPEVRSQVQQQSDSLIDRWQRLKYLAKQKATKIGELKMTLLRLEERIALIRAWLFEVESQLDKPLNFESYTPNVIEAKLKEHEQIQRSIEHHSSNVGEVLNLVEMLLNDADSWRTQVNTSGLAASAQNLEQRWKNVCSQSAERKARILTIWNLLQQLIKLTAEHKNWLGKQESQIAGFERDQKSHSKHKLEERQMELRAKLEELESQSVNLRQLEQIYAKLAMSAGVEPENIQKLTLPTKVMVSMWRQLTPRCHALLDAIDKDAKLMREFNNAQLEATNSLNAIQKALEQLPSAENQQTSKAEPKAVLQRLESLEKKLQDAQQHVQQADNLAQEAKTRTKQQPQLKQLLELVSAYTTLWQTVQTRIVTLKTTWLTRAAQAAASLPVSEAANAAVQVNTLSQRKLRQAQQMQRETSITAKDAYIMELQTAITECQNNLDELQRTVVDKTRKPGPQKIAKLLGNAQSSTELVKHLSHLLLTECKADDQAAEVDTVAELTLRFDTLQSQWKARQQHDQNASEVGRLTCPLCTQRNWQQIDNDLWRLEQWLQFAESTQKAQSAPPSNIELLEDVTQDHREFLLDLESHKSIISSLNVVGDHLATHTLDTEKARQLRSRLEADNERWNNVCINATKWQGLLQTALMGNSEFHQTIGELVEWLQRTEQNIKASEPVDLTEERSVLETKFKKFKDLRAELERCEPRVVSLQDAADQLLRSVEGSEQQSQHTYERTLSRLTDLRLRLQSLRRLSGIYIVKLGAVLGYEGDNLGVPLHMLSSELLDNTTLSTSSMQAAAPNTENANNTDGGDAVDGDVINTTVLARGARFLGRVARASLPIQALMLLLLGVATLVPHGEDYTCMFSNTFARSLEPMLSYPHGPPPT", "length": 12345 }, "evidence": [ { "id": "RGD:620546", "url": "https://alliancegenome.org/gene/RGD:620546#orthology", "database": "AGR" }, { "id": "HGNC:17089", "url": "https://alliancegenome.org/gene/HGNC:17089#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-071218-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-071218-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-4172", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-4172#orthology", "database": "AGR" }, { "id": "MGI:1927152", "url": "https://alliancegenome.org/gene/MGI:1927152#orthology", "database": "AGR" }, { "id": "FB:FBgn0261836", "url": "https://alliancegenome.org/gene/FB:FBgn0261836#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q6ZWR6-1", "protein_name": "Nesprin-1", "gene_name": "Syne1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATSRASSRSHRDITNVMQRLQDEQEIVQKRTFTKWINSHLAKRKPPMVVDDLFEDMKDGIKLLALLEVLSGQKLPCEQGHRVKRIHAVANIGTALKFLEGRKIKLVNINATDIADGRPSIVLGLMWTIILYFQIEELTSNLPQLQSLSSSASSVDSMVSTETASPPSKRKVAAKIQGNAKKTLLKWVQHTAGKQMGIEVKDFGKSWRTGLAFHSVIHAIQPELVDLEKVKTRSNRENLEDAFTIAETQLGIPRLLDPEDVDVDKPDEKSIMTYVAQFLTQYPDIHGAGCDGQEDDVVFVGFTNNIALLLGFQRDDRLILKETKVWIEQFERDFTRAQMTESSLQDKYQAFKHFRVQYEMKRKQVEHIIQPLQRDGKLTLDQALVKQCWERVSSRLFDWHIQLDKSLPAPLGTIGAWLYRAEVALREEITIQQVHEETANTIQRKLEQHKDLLQNTDAHKRAFHEIYQTRSVNGIPMPPDQLEDMAERFHFVSSTSELHLMKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVELLLQSYISFIENSKFFEQYEVTYQILKQTADIYVKAEGSVEEAENVMKFMSEATAQWRNLSVEVRSVRSMLEEVISNWDRYGDTVASLQAWLEDAEKMLSQSEHAKKDFFRNLPHWIQQHTAMNDAGNFLIETCDEIVSRDLKQQLLLLNGRWRELFMEVKQYARADEMDRMKKEYIDVTTTLFGFATEAHRKLSEPLEVSFINVKLLIQDLEDLEKRVPVMDAQYKMIAKKAHLFAKESPQEEANEMLTTMSKLKEQLSKVKECCSPLLYEAQQLTVPLEELETQITSFYDSLGKINEILSVLEQEAQSSTLFKQKHQELLASQENCKKSLTLIEKGSQSVQKLVTSSQARKPWDHTKLQKQIADVHHAFQSMIKKTGDWKKHVEANSRLMKKFEESRAELEKVLRVAQEGLEEKGDPEELLRRHTEFFSQLDQRVLNAFLKACDELTDILPEQEQQGLQEAVRKLHKQWKDLQGEAPYHLLHLKIAVEKDRFSAAVEECRAELEQETKLAPQEGSEKIIKEHRVFFSDKGPHHLCEKRLQLIEELCGKLPVQDPVRDTCGACHTALKELKASIDNTYTMLVDDPDKWKDYTSRFSEFSSWVSAKKACLKKIKDEPIDTGNHDEVKHMVDEIRNDITKKGESLSWLKSRLKYLIDISSENEAQKRGDELAELSSSFKALVALLSEVEKLLSNFGECVQYKEIVKSSLEGLISGPQESKEEAEMILDSKNLLEAQQLLLHHQQKTKMISAKKRDLQEQMEQAQQGGQAGPGQEELRKLESTLTGLEQSRERQERRIQVSLRKWERFETNKETVVRYLFQTGSSHERFLSFSSLESLSSELEQTKEFSKRTESIATQAENLVKEAAELPLGPRNKRVLQRQAKSIKEQVTTLEDTLEEDIKTMEMVKSKWDHFGSNFETLSIWILEKENELSSLEASASAADVQISQIKVTIQEIESKIDSIVGLEEEAQSFAQFVTTGESARIKAKLTQIRRYWEELQEHARGLEGTILGHLSQQQKFEENLRKIRQSVSEFAERLADPIKICSSAAETYKVLQEHMDLCQAVESLSSTVTMFSASAQKAVNRESCTQEAAALQQQYEEILHKAKEMQTALEDLLARWQRLEKGLSPFLTWLERCEAIASSPEKDISADRGKVESELQLIQALQNEVVSQASLYSNLLQLKEALFSVASKEDVAVMKLQLEQLDERWGDLPQIISKRMHFLQSVLAEHKQFDELLFSFSVWIKQFLGELQRTSEINLRDHQVALTRHKDHAAEIEKKRGEITHLQGHLSQLRSLGRAQDLHPLQSKVDDCFQLFEEASQVVERRKLALAQLAEFLQSHACMSTLLYQLRQTVEATKSMSKKQSDSLKTDLHSAIQDVKTLESSAISLDGTLTKAQCHLKSASPEERTSCRATTDQLSLEVERIQNLLGTKQSEADALVALKEAFREQKEELLRSIEDIEERMDRERLKVPTRQALQHRLRVFNQLEDELNSHEHELCWLKDKAKQIAQKDVAFAPEVDREINGLEATWDDTRRQIHENQGQCCGLIDLVREYQSLKSTVCNVLEDASNVVVMRATIKDQGDLKWAFSKHETSRNEMNSKQKELDSFTSKGKHLLSELKKIHSGDFSLVKTDMESTLDKWLDVSERIEENMDMLRVSLSIWDDVLSRKDEIEGWSNSSLPKLAENISNLNNSLRAEELLKELESEVKIKALKLEDLHSKINNLKELTKNPETPTELQFIEADLRQKLEHAKEITEEARGTLKDFTAQRTQVERFVKDITAWLINVEESLTRCAQTETCEGLKKAKDIRKELQSQQNSITSTQEELNSLCRKHHSVELESLGRAMTGLIKKHEATSQLCSQTQARIQDSLEKHFSGSMKEFQEWFLGAKAAARESSNLTGDSQILEARLHNLQGVLDSLSDGQSKLDVVTQEGQTLYAHLPKQIVSSIQEQITKANEEFQAFLKQCLKEKQALQDCVSELGSFEDQHRKLNLWIHEMEERLKTENLGESKHHISEKKNEVRKVEMFLGELLAARESLDKLSQRGQLLSEESHSAGKGGCRSTQLLTSYQSLLRVTKEKLRSCQLALKEHEALEEATQSMWARVKDVQDRLACAESTLGNKETLEGRLSQIQDILLMKGEGEVKLNLAIGKGDQALRSSNKEGQQAIQDQLEMLKKAWAEAMNSAVHAQSTLESVIDQWNDYLEKKSQLEQWMESVDQRLEHPLQLQPGLKEKFSLLDHFQSIVSEAEDHTGALQQLAAKSRELYQKTQDESFKEAGQEELRTQFQDIMTVAKEKMRTVEDLVKDHLMYLDAVQEFADWLHSAKEELHRWSDTSGDPSATQKKLLKIKELIDSREIGAGRLSRVESLAPAVKQNTAASGCELLNSEMQALRADWRQWEDCLFQTQSSLESLVSEMALSEQEFFGQVTQLEQALEQFCTLLKTWAQQLTLLEGKNSDEEILECWHKGREILDALQKAEPMTEDLKSQLNELCRFSRDLSPYSEKVSGLIKEYNCLCLQASKGCQNKEQILQERFQKASRGFQQWLVNAKITTAKCFDLPQNLSEVSSSLQKIQEFLSESENGQHKLNTMLFKGELLSSLLTEEKAQAVQAKVLTAKEEWKSFHANLHQKESALENLKIQMKDFEVSAELVQNWLSKTERLVQESSNRLYDLPAKRREQQKLQSVLEEIQCYEPQLHRLKEKARQLWEGQAASKSFVHRVSQLSSQYLALSNVTKEKVSRLDRIIAEHNRFSQGVKELQDWMSDAVHMLDSYCLPTSDKSVLDSRMLKLEALLSVRQEKEIQMKMVVTRGEYVLQSTSLEGSAAVQQQLQAVKDMWESLLSAAIRCKSQLEGALSKWTSYQDDVRQFSSWMDSVEVSLTESEKQHTELREKITALGKAKLLNEEVLSHSSLLETIEVKRAAMTEHYVTQLELQDLQERHQALKEKAKEAVTKLEKLVRLHQEYQRDLKAFESWLEQEQEKLDRCSVHEGDTNAHETMLRDLQELQVRCAEGQALLNSVLHTREDVIPSGLPQAEDRVLESLRQDWQVYQHRLAEARMQLNNVVNKLRLMEQKFQQADEWLKRMEEKINFRSECQSSRSDKEIQLLQLKKWHEDLSAHRDEVEEVGTRAQGILDETHISSRMGCQATQLTSRYQALLLQVLEQIKFFEEELQCLEETESSLSSYSDWYGSTHKNFKNVATKIDKVDESMMGKKLKTLEVLLKDMEKGHSLLKSAREKGERAMKFLAEHEAEALRKEIHTYMEQLKNLTSTVRKECMSLEKGLHLAKEFSDKYKVLAQWMAEYQEILCTPEEPKMELYEKKAQLSKYKSLQQMVLSHEPSVTSVQEKSEALLELVQDQSLKDKIQKLQSDFQDLCSRAKERVFSLEAKVKDHEDYNTELQEVEKWLLQMSGRLVAPDLLEMSSLETITQQLAHHKAMMEEIAGFEDRLDNLKAKGDTLIGQCPEHLQAKQKQTVQAHLQGTKDSYSAICSTAQRVYRSLEYELQKHVSSQDTLQQCQAWISAVQPDLKPSPQPPLSRAEAVKQVKHFRALQEQARTYLDLLCSMCDLSNSSVKNTAKDIQQTEQLIEQRLVQAQNLTQGWEEIKSLKAELWIYLQDADQQLQNMKRRHTELEINIAQNMVMQVKDFIKQLQCKQVSVSTIVEKVDKLTKNQESPEHKEITHLNDQWQDLCLQSDKLCAQREQDLQRTSSYHDHMRVVEAFLEKFTTEWDSLARSNAESTAIHLEALKKLALALQEEMYAIDDLKDCKQKLIEQLGLDDRELVREQTSHLEQRWFQLQDLVKRKIQVSVTNLEELNVIQSRFQELMEWAEEQQPNIVEALKQSPPPGMAQHLLMDHLAICSELEAKQVLLKSLMKDADRVMADLGLNERKVIQKALSEAQKHVSCLSDLVGQRRKYLNKALSEKTQFLMAVFQATSQIQQHERKIVFREYICLLPDDVSKQVKTCKTAQASLKTYQNEVTGLCAQGRELMKGITKQEQEEVLGKLQELQTVYDTVLQKCSHRLQELEKSLVSRKHFKEDFDKACHWLKQADIVTFPEINLMNEKTELHAQLDKYQSILEQSPEYENLLLTLQTTGQAMLPSLNEVDHSYLSEKLSALPQQFNVIVALAKDKFYKTQEAILARKEYTSLIELTTQSLGDLEDQFLKMRKMPSDLIVEESVSLQQSCSALLGEVVALGEAVNELNQKKESFRSTGQPWQPEKMLQLATLYHRLKRQAEQRVSFLEDTTSVYKEHAQMCRQLESQLEVVKREQAKVNEETLPAEEKLKVYHSLAGSLQDSGILLKRVATHLEDLSPHLDPTAYEKAKSQVQSWQEELKQMTSDVGELVTECESRMVQSIDFQTEMSRSLDWLRRVKAELSGPVCLDLSLQDIQEEIRKIQIHQEEVLSSLRIMSALSHKEQEKFTKAKELISADLEHTLAELQELDGDVQEALRTRQATLTEIYSRCQRYYQVFQAANDWLDDAQEMLQLAGNGLDVESAEENLRSHMEFFKTEGQFHSNMEELRGLVARLDPLIKATGKEELAQKMASLEKRSQGIIQESHTQRDLLQRCMVQWQEYQKAREGVIELMNDAEKKLSEFAVLKTSSIHEAEEKLSKHKALVSVVDSFHEKIVALEEKASQLEQTGNDTSKATLSRSMTTVWQRWTRLRAVAQDQEKILEDAVDEWKRLSAKVKETTEVINQLQGRLPGSSTEKASKAELMTLLESHDTYLMDLESQQLTLGVLQQRALSMLQDRAFPGTEEEVPILRAITALQDQCLNMQEKVKNHGKLVKQELQEREAVETRINSVKSWVQETKDYLGNPTIEIDTQLEELKRLLAEATSHQESIEKIAEEQKNKYLGLYTVLPSEISLQLAEVALDLKIHDQIQEKVQEIEEGKAMSQEFSCKIQKVTKDLTTILTKLKAKTDDLVHAKAEHKMLGEELDGCNSKLMELDAAIQTFSERHSQLGQPLAKKIGKLTELHQQTIRQAENRLSKLNQALSHMEEYNEMLETVRKWIEKAKVLVHGNIAWNSASQLQEQYILHQTLLEESGEIDSDLEAMAEKVQHLANVYCTGKLSQQVTQFGREMEELRQAIRVRLRNLQDAAKDMKKFEGELRNLQVALEQAQTILTSPEVGRRSLKEQLCHRQHLLSEMESLKPKMQAVQLCQSALRIPEDVVASLPLCHAALRLQEEASQLQHTAIQQCNIMQAKKHSLIFPPKEAVVQYEQYKQEMKHLQQLIEEAHREIEDKPVATSNIQELQAQISLHEELAQKIKGYQEQIDSLNSKCKMLTMKAKHATMLLTVTEVEGLAEGTEDLDRELHPTPSAHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEISSPPACRSPSPVANTEAAVNQDIAYYQALSAEGLQTDAARIPPSAAVSQELYEPGLEPSATAKLGDLQRSWETLKNVISEKQRTLYEVLERQQKYQDSLQSISTKMEAMEMKLGESLEPSRSPESQMAEHQALMDEVQMLQDEINGLQVSLAEELVAESQESDPAEQLALQSTLTVLAERMSTIRMKAAGKRQLLEEKLSDQLEEQRQEQALQRYRCEADELDHWLLNTKATLDVALGTSQEPMDMDAQLVDCQNMLVEIEQKVVALSQLSVHNENLLLEGKAHTKEEAEQLAVKLRLLKGSLGELQRALHDRQLDMQGVTQEKEENDVDFTDTQSPGVQEWLAQARTTRTHQRQSSLQQQKEFEQELAEQKSLLRSVASRGEEILTQHSTAEGSGGLGEKPDVLSQELGIAEDQMRVKWESLHQEFSAKQKLLQNILEQEQEQVLYSSPNRLLSGVLPFRGEAQTQDKTSVTSLLDGLSQAFGEASSQSGGTDRQSIHLEQKLYDGVSATSTWLNDVEERLFVATAPLPEETEACLFNQEALAKDIKEMSEEMDKNKNLFSQAFPEDSDNRDVIEDTLGCLLGRLSLLDSVVDQRCHQMKERLQQILRFQNDLKVLFTSLADSKYIILQKLANVFEQPIVEQMQAIQQAEEGLRDLEGGISELKRWADKLQVEQSAVQELSKLQDMYDELLMTVSSRRSSLHQNLALKSQYDKALQDLVDLLDTGQEKMTGDQKIIVCSKEEIQQLLGKHKEYFQGLESHMILTEILFRKIVGFAAVKETQFHTDCMAQASAVLKQAHKRGVELEYILEMWSHLDENRQELSRQLEVIENSIPSVGLVEESEDRLVERTNLYQHLKSSLNEYQPKLYQALDDGKRLLMSVSCSELESQLNQLGEHWLSNTNKVSKELHRLETILKHWTRYQSEAAALNHWLQCAKDRLAFWTQQSVTVPQELEMVRDHLSAFLEFSKEVDAKSALKSSVTSTGNQLLRLKKVDTAALRAELSRMDSQWTDLLTGIPVVQEKLHQLQMDKLPSRHAISEVMSWISLMESVILKDEEDIRNAIGYKAIHEYLQKYKGFKIDLNCKQLTADFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNKSWQLLQGRVGEKIQMLEGLLESWSEYENSVQSLKAWFANQERKLKEQHLLGDRNSVENALKDCQELEDLIKAKEKEVEKIEQNGLALIQNKREEVSGSVMSTLQELRQTWISLDRTVEQLKIQLTSALGQWSNHKAACDEINGHLMEARYSLSRFRLLTGSSEAVQVQVDNLQNLHDELEKQEGGLQKFGSITNQLLKECHPPVAETLSSTLQEVNMRWNNLLEEIAEQLHSSKALLQLWQRYKDYSKQCASAIQRQEEQTSVLLKAATNKDIADDEVTKWIQDCNDLLKGLETVKDSLFILRELGEQLGQQVDVSAAAAIQCEQLCFSQRLGALEQALCKQQAVLQAGVVDYETFAKSLEALEVWMVEAEGILQGQDPTHSSDLSTIQERMEELKGQMLKFSSLAPDLDRLNELGYRLPLNDKEIKRMQNLNRHWSLTSSQTTERFSKLQSFLLQHQTFLEKCETWMEFLVQTEHKLAVEISGNYQHLLEQQRAHELFQAEMFSRQQILHSIIVDGQNLLEQGQVDDREEFSLKLTLLSNQWQGVIRRAQQRRGIIDSQIRQWQRYREMAEKLRKWLAEVSHLPLSGLGNIPVPLQQVRMLFDEVQFKEKVFLRQQGSYILTVEAGKQLLLSADSGAEAALQAELTDIQEKWKAASMHLEEQKKKLAFLLKDWEKCERGIANSLEKLRMFKKRLSQPLPDHHEELHAEQMRCKELENAVGRWTDDLTELMLVRDALAVYLSAEDISMLKERVELLQRQWEELCHQVSLRRQQVSERLNEWAVFSEKNKELCEWLTQMESKVSQNGDILIEEMIEKLKKDYQEEIAVAQENKIQLQEMGERLAKASHESKASEIQYKLSRVKDRWQHLLDLMAARVKKLKETLVAVQQLDKNMGSLRTWLAHMESELAKPIVYDSCNSEEIQRKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATDAECDSIQQATRNLDRRWRNICAMSMERRLKIEETWRLWQKFLDDYSRFEDWLEVSERTAAFPSSSGVLYTVAKEELKKFEAFQRQVHESLTQLELINKQYRRLARENRTDSACSLRQMVHGGNQRWDDLQKRVTSILRRLKHFISQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNHNKIEQIIAQGEQLIEKSEPLDAAVIEEELDELRRYCQEVFGRVERYHKKLIRLPVRLPDDHDLSDRELDLEDSTALSDLRWQDPSADGMPSPQPSSNPSLSLPQPLRSERSGRDTPASVDSIPLEWDHDYDLSRDLESASRTLPSEDEEGEEDKEFYLRGAVGLSGDPSSLESQMRQLDKALDDSRFQIQQTANILRSKTPTGPDLDTSYKGYMKLLGECSGSIDSVRRLEHKLAEEESFPGFVNLNSTETQTAGVIDRWELLQAQAMSKELRMKQNLQKWQQFNSDLNNIWAWLGETEEELDRLQHLALSTDIHTIESHIKKLKELQKAVDHRKAIILSINLCSSEFTQADSKESHDLQDRLSQMNGRWDRVCSLLEDWRGLLQDALMQCQEFHEMSHALLLMLENIDRRKNEIVPIDSTLDPETLQDHHKQLMQIKQELLKSQLRVASLQDMSRQLLVNAEGSDCLEAKEKVHVIGNRLKLLLKEVSHHIKDLEKLLDMSSSQQDLSSWSSADELDTSGSVSPTSGRSTPNRQKSPRGKCSLSQPGPSVSSPKSRSTRDGSDSSRSDPRPERVGRAFLFRILRAALPFQLLLLLLIGLTCLVPMSEKDYSCALSNNFARSFHPMLRYTNGPPPL", "length": 8799 }, "evidence": [ { "id": "RGD:620546", "url": "https://alliancegenome.org/gene/RGD:620546#orthology", "database": "AGR" }, { "id": "HGNC:17089", "url": "https://alliancegenome.org/gene/HGNC:17089#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-071218-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-071218-4#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-4172", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-4172#orthology", "database": "AGR" }, { "id": "MGI:1927152", "url": "https://alliancegenome.org/gene/MGI:1927152#orthology", "database": "AGR" }, { "id": "FB:FBgn0261836", "url": "https://alliancegenome.org/gene/FB:FBgn0261836#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 9, "go_terms": [ { "name": "nuclear matrix anchoring at nuclear membrane", "id": "GO:0090292", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090292", "evidence": [ { "database": "UniProtKB", "id": "Q8NF91", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ], "pmid": "" }, { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "Q8NF91", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ], "pmid": "" }, { "name": "Golgi organization", "id": "GO:0007030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007030", "evidence": [ { "database": "UniProtKB", "id": "Q8NF91", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ], "pmid": "" }, { "name": "muscle cell differentiation", "id": "GO:0042692", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042692", "evidence": [ { "database": "UniProtKB", "id": "Q8NF91", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ], "pmid": "" }, { "name": "regulation of cilium assembly", "id": "GO:1902017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902017", "evidence": [ { "database": "UniProtKB", "id": "Q8NF91", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ], "pmid": "" }, { "name": "centrosome localization", "id": "GO:0051642", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051642", "evidence": [ { "database": "UniProtKB", "id": "Q8NF91", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ], "pmid": "" }, { "name": "nucleus organization", "id": "GO:0006997", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006997", "evidence": [ { "database": "UniProtKB", "id": "Q8NF91", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ], "pmid": "" }, { "name": "nuclear migration", "id": "GO:0007097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007097", "evidence": [ { "database": "UniProtKB", "id": "Q8NF91", "url": "https://www.uniprot.org/uniprotkb/Q8NF91" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", 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1152, 1156, 1158, 1160, 1161, 1162, 1165, 1167, 1169, 1171, 1172, 1177, 1179, 1180, 1186, 1189, 1190, 1191, 1193, 1195, 1197, 1198, 1202, 1204, 1206, 1213, 1216, 1219, 1223, 1224, 1226, 1228, 1229, 1230, 1232, 1233, 1234, 1239, 1242, 1244, 1246, 1247, 1248, 1249, 1250, 1251, 1252, 1253, 1254, 1255, 1256, 1257, 1258, 1260, 1261, 1266, 1272, 1276, 1277, 1278, 1284, 1287, 1288, 1289, 1290, 1291, 1293, 1294, 1297, 1299, 1301, 1302, 1303, 1304, 1308, 1309, 1311, 1312, 1313, 1314, 1315, 1318, 1320, 1321, 1322, 1324, 1325, 1326, 1328, 1329, 1331, 1332, 1333, 1334, 1336, 1337, 1339, 1340, 1342, 1343, 1344, 1347, 1350, 1352, 1359, 1361, 1362, 1363, 1364, 1365, 1368, 1369, 1374, 1380, 1385, 1388, 1389, 1390, 1391, 1393, 1395, 1396, 1397, 1401, 1402, 1405, 1407, 1409, 1410, 1411, 1421, 1423, 1425, 1427, 1430, 1431, 1432, 1433, 1435, 1438, 1439, 1440, 1441, 1442, 1443, 1444, 1450, 1454, 1456, 1458, 1459, 1460, 1461, 1462, 1464, 1468, 1469, 1474, 1475, 1476, 1478, 1480, 1482, 1494, 1497, 1499, 1500, 1502, 1505, 1508, 1509, 1513, 1514, 1515, 1521, 1523, 1524, 1525, 1526, 1531, 1533, 1534, 1537, 1540, 1545, 1549, 1550, 1552, 1554, 1556, 1557, 1558, 1559, 1566, 1567, 1572, 1575, 1576, 1582, 1583, 1590, 1592, 1593, 1595, 1600, 1602, 1605, 1608, 1611, 1612, 1613, 1614, 1616, 1617, 1622, 1624, 1627, 1628, 1629, 1630, 1631, 1633, 1637, 1638, 1640, 1642, 1643, 1644, 1647, 1648, 1649, 1651, 1653, 1655, 1657, 1659, 1661, 1663, 1669, 1679, 1683, 1684, 1685, 1686, 1699, 1704, 1705, 1708, 1710, 1716, 1720, 1721, 1722, 1723, 1728, 1729, 1730, 1731, 1735, 1737, 1741, 1743, 1744, 1747, 1750, 1751, 1752, 1756, 1757, 1759, 1761, 1766, 1769, 1771, 1776, 1777, 1780, 1781, 1787, 1790, 1793, 1799, 1800, 1804, 1805, 1808, 1810, 1812, 1814, 1819, 1823, 1825, 1826, 1829, 1830, 1831, 1833, 1834, 1835, 1839, 1843, 1844, 1845, 1846, 1847, 1849, 1851, 1853, 1855, 1856, 1859, 1860, 1861, 1862, 1863, 1866, 1868, 1869, 1871, 1872, 1874, 1879, 1882, 1885, 1887, 1888, 1889, 1892, 1894, 1896, 1897, 1898, 1899, 1900, 1901, 1904, 1906, 1908, 1910, 1912, 1914, 1917, 1920, 1921, 1923, 1924, 1927, 1928, 1929, 1930, 1934, 1936, 1937, 1940, 1941, 1942, 1943, 1947, 1948, 1950, 1951, 1952, 1953, 1954, 1956, 1958, 1959, 1960, 1965, 1970, 1974, 1975, 1980, 1987, 1988, 1995, 1996, 1997, 1998, 2002, 2004, 2005, 2008, 2011, 2012, 2013, 2015, 2018, 2019, 2025, 2027, 2030, 2031, 2032, 2033, 2035, 2037, 2046, 2049, 2050, 2055, 2058, 2062, 2064, 2066, 2068, 2069, 2074, 2078, 2079, 2083, 2086, 2090, 2092, 2096, 2097, 2101, 2103, 2105, 2106, 2109, 2111, 2112, 2116, 2117, 2118, 2120, 2121, 2122, 2123, 2124, 2125, 2129, 2133, 2134, 2141, 2149, 2155, 2157, 2163, 2167, 2168, 2169, 2183, 2185, 2187, 2189, 2190, 2191, 2195, 2199, 2200, 2201, 2204, 2207, 2210, 2213, 2216, 2217, 2218, 2219, 2220, 2222, 2225, 2230, 2232, 2233, 2235, 2236, 2238, 2241, 2242, 2245, 2248, 2249, 2251, 2253, 2256, 2257, 2258, 2260, 2264, 2269, 2270, 2271, 2274, 2276, 2278, 2281, 2284, 2293, 2295, 2301, 2303, 2304, 2308, 2309, 2312, 2313, 2315, 2316, 2317, 2318, 2319, 2320, 2324, 2325, 2326, 2327, 2331, 2334, 2335, 2348, 2349, 2350, 2351, 2355, 2356, 2359, 2363, 2364, 2365, 2366, 2368, 2369, 2380, 2381, 2382, 2385, 2386, 2389, 2391, 2392, 2396, 2400, 2401, 2402, 2405, 2408, 2409, 2413, 2417, 2420, 2421, 2423, 2426, 2427, 2431, 2433, 2435, 2436, 2437, 2438, 2441, 2442, 2443, 2445, 2446, 2447, 2449, 2451, 2453, 2454, 2461, 2462, 2463, 2464, 2465, 2467, 2469, 2474, 2476, 2478, 2479, 2482, 2484, 2486, 2489, 2492, 2495, 2499, 2500, 2501, 2504, 2506, 2507, 2510, 2512, 2515, 2516, 2520, 2522, 2523, 2524, 2527, 2530, 2532, 2533, 2536, 2537, 2538, 2540, 2541, 2545, 2546, 2551, 2554, 2556, 2557, 2561, 2562, 2563, 2564, 2565, 2570, 2575, 2578, 2579, 2585, 2588, 2589, 2590, 2591, 2592, 2593, 2594, 2595, 2596, 2602, 2603, 2606, 2607, 2610, 2611, 2613, 2617, 2619, 2623, 2627, 2628, 2630, 2633, 2634, 2641, 2642, 2645, 2646, 2648, 2651, 2654, 2657, 2659, 2663, 2665, 2668, 2671, 2672, 2673, 2675, 2677, 2678, 2680, 2683, 2684, 2687, 2688, 2689, 2692, 2696, 2710, 2714, 2715, 2716, 2720, 2722, 2723, 2724, 2729, 2730, 2732, 2734, 2735, 2738, 2739, 2740, 2745, 2746, 2747, 2748, 2753, 2755, 2756, 2757, 2759, 2768, 2769, 2771, 2775, 2781, 2784, 2786, 2787, 2788, 2789, 2792, 2800, 2802, 2808, 2814, 2815, 2818, 2820, 2823, 2825, 2826, 2827, 2830, 2832, 2836, 2837, 2841, 2843, 2848, 2851, 2852, 2855, 2857, 2861, 2864, 2865, 2868, 2881, 2889, 2891, 2894, 2896, 2898, 2899, 2900, 2902, 2904, 2905, 2907, 2909, 2913, 2914, 2915, 2917, 2922, 2925, 2927, 2930, 2932, 2935, 2936, 2940, 2941, 2943, 2947, 2948, 2959, 2960, 2961, 2968, 2970, 2973, 2974, 2978, 2979, 2985, 2991, 2994, 2996, 2999, 3008, 3012, 3014, 3017, 3018, 3021, 3022, 3023, 3024, 3026, 3027, 3028, 3032, 3034, 3038, 3039, 3046, 3050, 3051, 3052, 3054, 3057, 3058, 3063, 3069, 3070, 3071, 3077, 3080, 3081, 3083, 3088, 3092, 3093, 3096, 3099, 3101, 3103, 3104, 3106, 3119, 3123, 3124, 3125, 3127, 3129, 3130, 3131, 3133, 3135, 3138, 3140, 3142, 3147, 3154, 3161, 3162, 3163, 3165, 3167, 3169, 3171, 3174, 3177, 3183, 3184, 3186, 3190, 3193, 3197, 3201, 3202, 3209, 3210, 3216, 3218, 3219, 3222, 3223, 3228, 3229, 3234, 3241, 3242, 3244, 3247, 3249, 3253, 3256, 3259, 3260, 3263, 3269, 3275, 3276, 3279, 3280, 3281, 3285, 3290, 3292, 3294, 3297, 3298, 3299, 3301, 3305, 3308, 3309, 3310, 3312, 3317, 3318, 3320, 3326, 3330, 3336, 3343, 3344, 3346, 3347, 3349, 3353, 3354, 3355, 3357, 3360, 3362, 3364, 3367, 3368, 3376, 3377, 3379, 3382, 3385, 3388, 3393, 3394, 3397, 3399, 3401, 3402, 3407, 3408, 3409, 3410, 3411, 3417, 3420, 3421, 3423, 3426, 3427, 3428, 3430, 3431, 3438, 3442, 3445, 3449, 3450, 3453, 3454, 3457, 3458, 3460, 3465, 3472, 3474, 3478, 3480, 3481, 3483, 3484, 3486, 3490, 3492, 3499, 3503, 3505, 3509, 3510, 3513, 3516, 3519, 3521, 3524, 3525, 3528, 3533, 3539, 3550, 3551, 3552, 3556, 3559, 3565, 3567, 3568, 3569, 3571, 3574, 3576, 3580, 3583, 3588, 3590, 3594, 3595, 3596, 3600, 3604, 3609, 3610, 3617, 3618, 3620, 3623, 3624, 3631, 3632, 3633, 3639, 3640, 3644, 3645, 3648, 3650, 3652, 3658, 3660, 3662, 3663, 3665, 3668, 3671, 3674, 3687, 3688, 3694, 3695, 3698, 3702, 3705, 3713, 3714, 3716, 3719, 3727, 3729, 3730, 3732, 3734, 3738, 3739, 3740, 3741, 3742, 3744, 3745, 3747, 3749, 3756, 3762, 3768, 3769, 3771, 3772, 3774, 3775, 3777, 3782, 3784, 3787, 3789, 3791, 3798, 3799, 3801, 3802, 3803, 3804, 3805, 3807, 3808, 3810, 3814, 3816, 3820, 3821, 3830, 3831, 3837, 3838, 3843, 3845, 3849, 3854, 3855, 3863, 3865, 3867, 3871, 3876, 3880, 3881, 3882, 3883, 3897, 3902, 3903, 3905, 3907, 3909, 3910, 3915, 3917, 3918, 3919, 3920, 3921, 3923, 3925, 3930, 3931, 3932, 3934, 3936, 3937, 3939, 3940, 3941, 3944, 3949, 3950, 3952, 3961, 3965, 3966, 3968, 3969, 3972, 3974, 3979, 3980, 3983, 3984, 3987, 3988, 3992, 3993, 4000, 4001, 4012, 4013, 4018, 4019, 4020, 4021, 4022, 4026, 4027, 4029, 4032, 4033, 4034, 4037, 4039, 4041, 4044, 4045, 4046, 4050, 4051, 4052, 4053, 4057, 4060, 4061, 4063, 4064, 4069, 4077, 4085, 4088, 4089, 4091, 4093, 4095, 4098, 4101, 4103, 4105, 4106, 4111, 4114, 4115, 4116, 4117, 4125, 4126, 4130, 4131, 4141, 4143, 4146, 4147, 4149, 4156, 4161, 4162, 4167, 4171, 4172, 4173, 4184, 4185, 4189, 4191, 4192, 4195, 4200, 4213, 4214, 4215, 4218, 4220, 4221, 4223, 4228, 4232, 4233, 4234, 4235, 4238, 4241, 4246, 4247, 4250, 4256, 4258, 4259, 4262, 4264, 4265, 4266, 4269, 4271, 4273, 4284, 4286, 4288, 4290, 4291, 4293, 4297, 4304, 4316, 4319, 4320, 4322, 4324, 4325, 4329, 4330, 4333, 4334, 4340, 4341, 4342, 4343, 4345, 4350, 4351, 4354, 4355, 4357, 4360, 4367, 4368, 4369, 4372, 4373, 4376, 4377, 4381, 4384, 4389, 4393, 4403, 4404, 4406, 4407, 4408, 4415, 4419, 4420, 4427, 4428, 4429, 4432, 4433, 4437, 4438, 4441, 4444, 4445, 4449, 4453, 4454, 4459, 4462, 4463, 4464, 4469, 4474, 4479, 4480, 4481, 4483, 4493, 4495, 4498, 4502, 4504, 4510, 4513, 4515, 4517, 4518, 4519, 4521, 4524, 4525, 4526, 4528, 4531, 4533, 4534, 4538, 4543, 4549, 4550, 4553, 4555, 4557, 4559, 4563, 4564, 4566, 4571, 4572, 4573, 4581, 4582, 4583, 4590, 4596, 4598, 4599, 4604, 4605, 4610, 4616, 4618, 4620, 4621, 4626, 4627, 4632, 4637, 4638, 4640, 4641, 4642, 4643, 4647, 4649, 4650, 4654, 4655, 4657, 4661, 4662, 4663, 4666, 4667, 4671, 4672, 4673, 4675, 4678, 4684, 4685, 4689, 4690, 4691, 4694, 4697, 4700, 4701, 4703, 4706, 4707, 4708, 4709, 4710, 4713, 4714, 4721, 4722, 4725, 4728, 4729, 4731, 4735, 4736, 4741, 4742, 4743, 4745, 4746, 4748, 4753, 4756, 4764, 4767, 4768, 4769, 4770, 4775, 4776, 4778, 4780, 4781, 4784, 4785, 4786, 4787, 4789, 4796, 4797, 4798, 4799, 4804, 4807, 4808, 4809, 4810, 4811, 4814, 4818, 4819, 4822, 4827, 4829, 4830, 4831, 4834, 4844, 4846, 4848, 4851, 4854, 4857, 4859, 4860, 4861, 4868, 4871, 4874, 4875, 4878, 4879, 4880, 4882, 4883, 4886, 4887, 4894, 4895, 4896, 4897, 4899, 4901, 4903, 4906, 4910, 4916, 4919, 4921, 4925, 4930, 4932, 4933, 4936, 4937, 4940, 4943, 4946, 4950, 4955, 4956, 4957, 4958, 4960, 4961, 4962, 4964, 4965, 4968, 4970, 4972, 4974, 4975, 4977, 4981, 4982, 4984, 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5453, 5454, 5456, 5459, 5461, 5466, 5467, 5470, 5472, 5478, 5479, 5481, 5484, 5486, 5487, 5488, 5493, 5498, 5499, 5500, 5501, 5503, 5504, 5505, 5507, 5509, 5516, 5518, 5519, 5523, 5524, 5534, 5540, 5542, 5557, 5558, 5559, 5562, 5563, 5569, 5570, 5574, 5575, 5578, 5580, 5581, 5590, 5591, 5592, 5594, 5595, 5596, 5601, 5604, 5605, 5607, 5611, 5617, 5618, 5619, 5623, 5624, 5627, 5628, 5632, 5637, 5638, 5639, 5640, 5642, 5645, 5647, 5652, 5653, 5654, 5656, 5657, 5658, 5661, 5662, 5664, 5670, 5672, 5677, 5679, 5681, 5684, 5687, 5695, 5697, 5698, 5700, 5705, 5712, 5714, 5720, 5726, 5727, 5728, 5738, 5750, 5751, 5757, 5758, 5760, 5761, 5762, 5767, 5769, 5779, 5780, 5781, 5789, 5793, 5794, 5797, 5800, 5803, 5811, 5812, 5814, 5817, 5820, 5823, 5826, 5833, 5834, 5837, 5839, 5840, 5841, 5842, 5852, 5859, 5861, 5862, 5864, 5865, 5866, 5868, 5869, 5872, 5874, 5876, 5877, 5879, 5880, 5883, 5889, 5894, 5895, 5902, 5905, 5909, 5910, 5917, 5922, 5924, 5927, 5930, 5931, 5933, 5935, 5936, 5938, 5941, 5942, 5943, 5945, 5949, 5950, 5951, 5954, 5956, 5958, 5961, 5964, 5966, 5972, 5974, 5977, 5978, 5982, 5986, 5988, 5989, 5992, 5996, 5997, 6011, 6016, 6019, 6024, 6026, 6029, 6031, 6032, 6034, 6035, 6036, 6037, 6038, 6039, 6040, 6042, 6045, 6053, 6055, 6056, 6057, 6059, 6062, 6065, 6068, 6069, 6072, 6074, 6078, 6081, 6083, 6088, 6089, 6095, 6096, 6106, 6109, 6110, 6113, 6114, 6115, 6120, 6122, 6125, 6135, 6140, 6148, 6156, 6159, 6160, 6163, 6170, 6171, 6173, 6174, 6178, 6186, 6190, 6191, 6192, 6194, 6196, 6198, 6202, 6205, 6206, 6207, 6209, 6210, 6211, 6214, 6220, 6228, 6230, 6232, 6235, 6236, 6237, 6247, 6248, 6249, 6252, 6255, 6257, 6261, 6263, 6265, 6266, 6267, 6271, 6273, 6275, 6284, 6286, 6289, 6291, 6292, 6294, 6296, 6298, 6299, 6303, 6305, 6310, 6315, 6317, 6318, 6322, 6327, 6329, 6331, 6336, 6337, 6338, 6341, 6342, 6343, 6347, 6349, 6353, 6355, 6356, 6363, 6364, 6367, 6370, 6376, 6380, 6384, 6386, 6389, 6390, 6397, 6398, 6399, 6400, 6405, 6406, 6408, 6409, 6417, 6420, 6422, 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